Amino acid dipepetide frequency for Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638) (Delacroixia coronata)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.356AlaAla: 3.356 ± 0.04
0.808AlaCys: 0.808 ± 0.015
2.293AlaAsp: 2.293 ± 0.029
2.856AlaGlu: 2.856 ± 0.038
2.238AlaPhe: 2.238 ± 0.025
2.804AlaGly: 2.804 ± 0.038
1.137AlaHis: 1.137 ± 0.018
3.97AlaIle: 3.97 ± 0.035
3.808AlaLys: 3.808 ± 0.038
5.096AlaLeu: 5.096 ± 0.043
1.03AlaMet: 1.03 ± 0.018
3.084AlaAsn: 3.084 ± 0.031
2.496AlaPro: 2.496 ± 0.036
2.327AlaGln: 2.327 ± 0.033
1.881AlaArg: 1.881 ± 0.028
4.336AlaSer: 4.336 ± 0.04
3.115AlaThr: 3.115 ± 0.036
2.851AlaVal: 2.851 ± 0.036
0.505AlaTrp: 0.505 ± 0.012
1.883AlaTyr: 1.883 ± 0.025
0.0AlaXaa: 0.0 ± 0.0
Cys
0.679CysAla: 0.679 ± 0.013
0.283CysCys: 0.283 ± 0.013
0.695CysAsp: 0.695 ± 0.016
0.696CysGlu: 0.696 ± 0.015
0.74CysPhe: 0.74 ± 0.015
0.824CysGly: 0.824 ± 0.019
0.345CysHis: 0.345 ± 0.011
1.135CysIle: 1.135 ± 0.018
1.057CysLys: 1.057 ± 0.021
1.513CysLeu: 1.513 ± 0.024
0.31CysMet: 0.31 ± 0.01
0.796CysAsn: 0.796 ± 0.015
0.68CysPro: 0.68 ± 0.019
0.565CysGln: 0.565 ± 0.012
0.542CysArg: 0.542 ± 0.013
1.182CysSer: 1.182 ± 0.02
0.77CysThr: 0.77 ± 0.017
0.759CysVal: 0.759 ± 0.016
0.172CysTrp: 0.172 ± 0.008
0.658CysTyr: 0.658 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
2.352AspAla: 2.352 ± 0.031
0.696AspCys: 0.696 ± 0.015
3.071AspAsp: 3.071 ± 0.041
3.577AspGlu: 3.577 ± 0.042
2.534AspPhe: 2.534 ± 0.029
2.504AspGly: 2.504 ± 0.032
1.152AspHis: 1.152 ± 0.02
3.962AspIle: 3.962 ± 0.035
3.531AspLys: 3.531 ± 0.037
5.55AspLeu: 5.55 ± 0.047
1.019AspMet: 1.019 ± 0.017
3.195AspAsn: 3.195 ± 0.031
2.599AspPro: 2.599 ± 0.027
2.213AspGln: 2.213 ± 0.03
1.994AspArg: 1.994 ± 0.026
4.45AspSer: 4.45 ± 0.047
2.559AspThr: 2.559 ± 0.026
2.431AspVal: 2.431 ± 0.026
0.668AspTrp: 0.668 ± 0.014
2.45AspTyr: 2.45 ± 0.027
0.0AspXaa: 0.0 ± 0.0
Glu
3.368GluAla: 3.368 ± 0.042
0.79GluCys: 0.79 ± 0.017
3.702GluAsp: 3.702 ± 0.04
4.966GluGlu: 4.966 ± 0.062
3.305GluPhe: 3.305 ± 0.034
2.78GluGly: 2.78 ± 0.033
1.154GluHis: 1.154 ± 0.02
4.099GluIle: 4.099 ± 0.037
4.088GluLys: 4.088 ± 0.036
6.851GluLeu: 6.851 ± 0.054
1.162GluMet: 1.162 ± 0.018
3.495GluAsn: 3.495 ± 0.031
1.921GluPro: 1.921 ± 0.028
2.107GluGln: 2.107 ± 0.026
2.201GluArg: 2.201 ± 0.025
4.435GluSer: 4.435 ± 0.044
2.949GluThr: 2.949 ± 0.034
3.371GluVal: 3.371 ± 0.036
0.651GluTrp: 0.651 ± 0.014
2.421GluTyr: 2.421 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
2.252PheAla: 2.252 ± 0.028
0.725PheCys: 0.725 ± 0.015
2.895PheAsp: 2.895 ± 0.03
2.899PheGlu: 2.899 ± 0.031
1.97PhePhe: 1.97 ± 0.027
2.838PheGly: 2.838 ± 0.037
0.992PheHis: 0.992 ± 0.018
3.568PheIle: 3.568 ± 0.035
3.414PheLys: 3.414 ± 0.034
4.115PheLeu: 4.115 ± 0.04
0.899PheMet: 0.899 ± 0.016
3.674PheAsn: 3.674 ± 0.035
1.959PhePro: 1.959 ± 0.025
1.848PheGln: 1.848 ± 0.024
1.578PheArg: 1.578 ± 0.02
3.94PheSer: 3.94 ± 0.037
2.67PheThr: 2.67 ± 0.03
2.404PheVal: 2.404 ± 0.03
0.532PheTrp: 0.532 ± 0.014
1.907PheTyr: 1.907 ± 0.023
0.001PheXaa: 0.001 ± 0.0
Gly
2.832GlyAla: 2.832 ± 0.04
0.785GlyCys: 0.785 ± 0.017
2.624GlyAsp: 2.624 ± 0.032
2.705GlyGlu: 2.705 ± 0.031
2.666GlyPhe: 2.666 ± 0.033
3.771GlyGly: 3.771 ± 0.063
1.243GlyHis: 1.243 ± 0.022
3.719GlyIle: 3.719 ± 0.042
3.407GlyLys: 3.407 ± 0.037
5.004GlyLeu: 5.004 ± 0.044
1.024GlyMet: 1.024 ± 0.02
2.837GlyAsn: 2.837 ± 0.039
1.808GlyPro: 1.808 ± 0.028
1.849GlyGln: 1.849 ± 0.031
1.907GlyArg: 1.907 ± 0.026
4.229GlySer: 4.229 ± 0.039
2.757GlyThr: 2.757 ± 0.033
3.094GlyVal: 3.094 ± 0.034
0.721GlyTrp: 0.721 ± 0.016
2.451GlyTyr: 2.451 ± 0.037
0.0GlyXaa: 0.0 ± 0.0
His
0.934HisAla: 0.934 ± 0.016
0.39HisCys: 0.39 ± 0.011
0.935HisAsp: 0.935 ± 0.019
0.97HisGlu: 0.97 ± 0.016
1.094HisPhe: 1.094 ± 0.019
1.095HisGly: 1.095 ± 0.02
0.77HisHis: 0.77 ± 0.023
1.477HisIle: 1.477 ± 0.02
1.219HisLys: 1.219 ± 0.017
2.431HisLeu: 2.431 ± 0.028
0.417HisMet: 0.417 ± 0.011
1.196HisAsn: 1.196 ± 0.019
1.336HisPro: 1.336 ± 0.022
0.934HisGln: 0.934 ± 0.017
0.996HisArg: 0.996 ± 0.018
1.883HisSer: 1.883 ± 0.03
1.071HisThr: 1.071 ± 0.02
0.958HisVal: 0.958 ± 0.018
0.277HisTrp: 0.277 ± 0.009
0.937HisTyr: 0.937 ± 0.017
0.0HisXaa: 0.0 ± 0.0
Ile
3.711IleAla: 3.711 ± 0.035
1.174IleCys: 1.174 ± 0.02
4.063IleAsp: 4.063 ± 0.034
4.406IleGlu: 4.406 ± 0.034
3.341IlePhe: 3.341 ± 0.032
3.687IleGly: 3.687 ± 0.04
1.564IleHis: 1.564 ± 0.022
5.229IleIle: 5.229 ± 0.045
5.293IleLys: 5.293 ± 0.045
7.034IleLeu: 7.034 ± 0.05
1.371IleMet: 1.371 ± 0.019
5.002IleAsn: 5.002 ± 0.046
3.572IlePro: 3.572 ± 0.032
3.13IleGln: 3.13 ± 0.033
2.646IleArg: 2.646 ± 0.025
6.072IleSer: 6.072 ± 0.051
3.962IleThr: 3.962 ± 0.035
3.851IleVal: 3.851 ± 0.041
0.783IleTrp: 0.783 ± 0.013
2.774IleTyr: 2.774 ± 0.031
0.0IleXaa: 0.0 ± 0.0
Lys
3.674LysAla: 3.674 ± 0.038
1.04LysCys: 1.04 ± 0.022
3.856LysAsp: 3.856 ± 0.035
4.519LysGlu: 4.519 ± 0.043
3.756LysPhe: 3.756 ± 0.039
2.927LysGly: 2.927 ± 0.031
1.388LysHis: 1.388 ± 0.02
4.604LysIle: 4.604 ± 0.042
5.124LysLys: 5.124 ± 0.06
8.618LysLeu: 8.618 ± 0.065
1.266LysMet: 1.266 ± 0.017
4.116LysAsn: 4.116 ± 0.04
3.08LysPro: 3.08 ± 0.039
2.59LysGln: 2.59 ± 0.028
2.78LysArg: 2.78 ± 0.032
5.817LysSer: 5.817 ± 0.048
3.541LysThr: 3.541 ± 0.034
4.107LysVal: 4.107 ± 0.037
0.778LysTrp: 0.778 ± 0.014
2.907LysTyr: 2.907 ± 0.032
0.0LysXaa: 0.0 ± 0.0
Leu
5.649LeuAla: 5.649 ± 0.043
1.329LeuCys: 1.329 ± 0.019
5.495LeuAsp: 5.495 ± 0.044
6.393LeuGlu: 6.393 ± 0.055
4.45LeuPhe: 4.45 ± 0.04
5.096LeuGly: 5.096 ± 0.047
1.882LeuHis: 1.882 ± 0.022
7.935LeuIle: 7.935 ± 0.065
8.215LeuLys: 8.215 ± 0.062
9.143LeuLeu: 9.143 ± 0.059
2.042LeuMet: 2.042 ± 0.027
7.292LeuAsn: 7.292 ± 0.054
4.886LeuPro: 4.886 ± 0.04
3.569LeuGln: 3.569 ± 0.035
3.56LeuArg: 3.56 ± 0.032
8.632LeuSer: 8.632 ± 0.051
6.281LeuThr: 6.281 ± 0.048
5.755LeuVal: 5.755 ± 0.046
0.83LeuTrp: 0.83 ± 0.015
3.346LeuTyr: 3.346 ± 0.033
0.0LeuXaa: 0.0 ± 0.0
Met
1.188MetAla: 1.188 ± 0.022
0.249MetCys: 0.249 ± 0.009
1.195MetAsp: 1.195 ± 0.019
1.266MetGlu: 1.266 ± 0.022
0.794MetPhe: 0.794 ± 0.016
1.133MetGly: 1.133 ± 0.02
0.321MetHis: 0.321 ± 0.008
1.339MetIle: 1.339 ± 0.018
1.429MetLys: 1.429 ± 0.019
1.73MetLeu: 1.73 ± 0.02
0.468MetMet: 0.468 ± 0.011
1.269MetAsn: 1.269 ± 0.022
0.777MetPro: 0.777 ± 0.015
0.601MetGln: 0.601 ± 0.013
0.729MetArg: 0.729 ± 0.015
1.729MetSer: 1.729 ± 0.022
1.141MetThr: 1.141 ± 0.017
1.221MetVal: 1.221 ± 0.02
0.158MetTrp: 0.158 ± 0.006
0.618MetTyr: 0.618 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
2.722AsnAla: 2.722 ± 0.031
0.963AsnCys: 0.963 ± 0.019
2.957AsnAsp: 2.957 ± 0.031
3.439AsnGlu: 3.439 ± 0.031
3.156AsnPhe: 3.156 ± 0.033
3.152AsnGly: 3.152 ± 0.034
1.367AsnHis: 1.367 ± 0.02
4.65AsnIle: 4.65 ± 0.04
3.729AsnLys: 3.729 ± 0.038
7.368AsnLeu: 7.368 ± 0.056
1.365AsnMet: 1.365 ± 0.018
5.069AsnAsn: 5.069 ± 0.088
3.532AsnPro: 3.532 ± 0.037
3.109AsnGln: 3.109 ± 0.039
2.394AsnArg: 2.394 ± 0.027
6.233AsnSer: 6.233 ± 0.06
3.759AsnThr: 3.759 ± 0.04
2.794AsnVal: 2.794 ± 0.026
0.909AsnTrp: 0.909 ± 0.016
2.874AsnTyr: 2.874 ± 0.03
0.0AsnXaa: 0.0 ± 0.0
Pro
2.397ProAla: 2.397 ± 0.031
0.503ProCys: 0.503 ± 0.014
2.219ProAsp: 2.219 ± 0.027
3.032ProGlu: 3.032 ± 0.033
1.899ProPhe: 1.899 ± 0.026
2.088ProGly: 2.088 ± 0.03
1.007ProHis: 1.007 ± 0.019
3.378ProIle: 3.378 ± 0.034
3.394ProLys: 3.394 ± 0.032
4.013ProLeu: 4.013 ± 0.041
0.796ProMet: 0.796 ± 0.016
3.337ProAsn: 3.337 ± 0.033
2.893ProPro: 2.893 ± 0.071
2.144ProGln: 2.144 ± 0.031
1.559ProArg: 1.559 ± 0.024
4.524ProSer: 4.524 ± 0.058
3.145ProThr: 3.145 ± 0.041
2.583ProVal: 2.583 ± 0.032
0.398ProTrp: 0.398 ± 0.011
1.667ProTyr: 1.667 ± 0.023
0.0ProXaa: 0.0 ± 0.0
Gln
2.385GlnAla: 2.385 ± 0.027
0.544GlnCys: 0.544 ± 0.014
1.824GlnAsp: 1.824 ± 0.023
2.143GlnGlu: 2.143 ± 0.025
2.126GlnPhe: 2.126 ± 0.028
1.784GlnGly: 1.784 ± 0.026
0.817GlnHis: 0.817 ± 0.018
2.846GlnIle: 2.846 ± 0.032
2.499GlnLys: 2.499 ± 0.029
4.822GlnLeu: 4.822 ± 0.04
0.818GlnMet: 0.818 ± 0.014
2.527GlnAsn: 2.527 ± 0.032
1.909GlnPro: 1.909 ± 0.032
1.982GlnGln: 1.982 ± 0.041
1.49GlnArg: 1.49 ± 0.022
3.417GlnSer: 3.417 ± 0.034
2.222GlnThr: 2.222 ± 0.026
2.442GlnVal: 2.442 ± 0.024
0.411GlnTrp: 0.411 ± 0.011
1.575GlnTyr: 1.575 ± 0.022
0.0GlnXaa: 0.0 ± 0.0
Arg
2.012ArgAla: 2.012 ± 0.028
0.55ArgCys: 0.55 ± 0.012
2.005ArgAsp: 2.005 ± 0.026
2.257ArgGlu: 2.257 ± 0.027
1.762ArgPhe: 1.762 ± 0.022
1.917ArgGly: 1.917 ± 0.025
0.82ArgHis: 0.82 ± 0.016
2.522ArgIle: 2.522 ± 0.03
2.733ArgLys: 2.733 ± 0.028
3.689ArgLeu: 3.689 ± 0.034
0.792ArgMet: 0.792 ± 0.015
2.132ArgAsn: 2.132 ± 0.024
1.574ArgPro: 1.574 ± 0.023
1.411ArgGln: 1.411 ± 0.023
1.943ArgArg: 1.943 ± 0.031
3.007ArgSer: 3.007 ± 0.04
1.826ArgThr: 1.826 ± 0.024
2.31ArgVal: 2.31 ± 0.027
0.413ArgTrp: 0.413 ± 0.01
1.496ArgTyr: 1.496 ± 0.022
0.0ArgXaa: 0.0 ± 0.0
Ser
4.268SerAla: 4.268 ± 0.038
1.083SerCys: 1.083 ± 0.019
4.191SerAsp: 4.191 ± 0.039
4.724SerGlu: 4.724 ± 0.043
3.715SerPhe: 3.715 ± 0.04
4.352SerGly: 4.352 ± 0.039
1.831SerHis: 1.831 ± 0.028
6.461SerIle: 6.461 ± 0.048
6.245SerLys: 6.245 ± 0.05
8.436SerLeu: 8.436 ± 0.055
1.501SerMet: 1.501 ± 0.018
6.138SerAsn: 6.138 ± 0.065
4.054SerPro: 4.054 ± 0.05
3.693SerGln: 3.693 ± 0.04
3.052SerArg: 3.052 ± 0.036
8.78SerSer: 8.78 ± 0.113
5.373SerThr: 5.373 ± 0.049
4.153SerVal: 4.153 ± 0.035
0.837SerTrp: 0.837 ± 0.016
3.125SerTyr: 3.125 ± 0.032
0.0SerXaa: 0.0 ± 0.0
Thr
2.866ThrAla: 2.866 ± 0.036
0.803ThrCys: 0.803 ± 0.016
2.605ThrAsp: 2.605 ± 0.033
2.973ThrGlu: 2.973 ± 0.033
2.384ThrPhe: 2.384 ± 0.026
2.947ThrGly: 2.947 ± 0.038
1.213ThrHis: 1.213 ± 0.016
4.304ThrIle: 4.304 ± 0.039
3.905ThrLys: 3.905 ± 0.036
5.972ThrLeu: 5.972 ± 0.041
0.953ThrMet: 0.953 ± 0.015
3.622ThrAsn: 3.622 ± 0.038
3.155ThrPro: 3.155 ± 0.034
2.447ThrGln: 2.447 ± 0.027
1.983ThrArg: 1.983 ± 0.028
5.002ThrSer: 5.002 ± 0.049
4.206ThrThr: 4.206 ± 0.165
3.016ThrVal: 3.016 ± 0.029
0.661ThrTrp: 0.661 ± 0.013
1.974ThrTyr: 1.974 ± 0.023
0.0ThrXaa: 0.0 ± 0.0
Val
3.043ValAla: 3.043 ± 0.034
0.776ValCys: 0.776 ± 0.017
3.119ValAsp: 3.119 ± 0.028
3.33ValGlu: 3.33 ± 0.038
2.401ValPhe: 2.401 ± 0.028
2.977ValGly: 2.977 ± 0.04
1.095ValHis: 1.095 ± 0.019
3.948ValIle: 3.948 ± 0.037
3.997ValLys: 3.997 ± 0.039
4.939ValLeu: 4.939 ± 0.041
1.071ValMet: 1.071 ± 0.018
3.487ValAsn: 3.487 ± 0.033
2.49ValPro: 2.49 ± 0.03
2.053ValGln: 2.053 ± 0.024
1.926ValArg: 1.926 ± 0.025
4.057ValSer: 4.057 ± 0.037
2.911ValThr: 2.911 ± 0.033
3.216ValVal: 3.216 ± 0.037
0.56ValTrp: 0.56 ± 0.013
2.112ValTyr: 2.112 ± 0.024
0.0ValXaa: 0.0 ± 0.0
Trp
0.573TrpAla: 0.573 ± 0.013
0.186TrpCys: 0.186 ± 0.007
0.698TrpAsp: 0.698 ± 0.017
0.633TrpGlu: 0.633 ± 0.015
0.543TrpPhe: 0.543 ± 0.011
0.68TrpGly: 0.68 ± 0.015
0.194TrpHis: 0.194 ± 0.007
0.829TrpIle: 0.829 ± 0.015
0.819TrpLys: 0.819 ± 0.015
1.022TrpLeu: 1.022 ± 0.019
0.229TrpMet: 0.229 ± 0.008
0.719TrpAsn: 0.719 ± 0.014
0.289TrpPro: 0.289 ± 0.009
0.323TrpGln: 0.323 ± 0.009
0.441TrpArg: 0.441 ± 0.012
0.923TrpSer: 0.923 ± 0.016
0.619TrpThr: 0.619 ± 0.012
0.605TrpVal: 0.605 ± 0.014
0.159TrpTrp: 0.159 ± 0.007
0.424TrpTyr: 0.424 ± 0.012
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.613TyrAla: 1.613 ± 0.022
0.722TyrCys: 0.722 ± 0.013
2.066TyrAsp: 2.066 ± 0.027
2.03TyrGlu: 2.03 ± 0.026
2.209TyrPhe: 2.209 ± 0.029
2.076TyrGly: 2.076 ± 0.034
1.025TyrHis: 1.025 ± 0.02
2.688TyrIle: 2.688 ± 0.027
2.582TyrLys: 2.582 ± 0.027
4.434TyrLeu: 4.434 ± 0.043
0.821TyrMet: 0.821 ± 0.013
2.553TyrAsn: 2.553 ± 0.032
1.967TyrPro: 1.967 ± 0.036
1.69TyrGln: 1.69 ± 0.025
1.57TyrArg: 1.57 ± 0.019
3.362TyrSer: 3.362 ± 0.035
2.111TyrThr: 2.111 ± 0.029
1.592TyrVal: 1.592 ± 0.023
0.485TyrTrp: 0.485 ± 0.011
1.983TyrTyr: 1.983 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10567 proteins (3652955 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski