Chicken associated cyclovirus 2

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Cyclovirus

Average proteome isoelectric point is 8.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A346BLF6|A0A346BLF6_9CIRC Capsid protein OS=Chicken associated cyclovirus 2 OX=2109365 PE=4 SV=1
MM1 pKa = 7.25LRR3 pKa = 11.84ARR5 pKa = 11.84RR6 pKa = 11.84FGSIKK11 pKa = 10.25KK12 pKa = 9.55ILGHH16 pKa = 6.89RR17 pKa = 11.84IHH19 pKa = 7.42IEE21 pKa = 3.7RR22 pKa = 11.84SNGSDD27 pKa = 2.9VDD29 pKa = 3.78NQKK32 pKa = 10.39YY33 pKa = 9.66CSKK36 pKa = 11.17GGDD39 pKa = 3.49FWEE42 pKa = 5.04HH43 pKa = 6.86GSPQGQGKK51 pKa = 10.26RR52 pKa = 11.84NDD54 pKa = 4.18LISIVEE60 pKa = 4.4EE61 pKa = 4.09IKK63 pKa = 11.03SGTGLVEE70 pKa = 3.35ICEE73 pKa = 4.12NHH75 pKa = 5.68TEE77 pKa = 4.11SFIRR81 pKa = 11.84YY82 pKa = 8.64HH83 pKa = 7.82SGIEE87 pKa = 3.55KK88 pKa = 9.65AYY90 pKa = 9.66RR91 pKa = 11.84YY92 pKa = 9.45IGRR95 pKa = 11.84GCNDD99 pKa = 3.8RR100 pKa = 11.84NWKK103 pKa = 8.5TKK105 pKa = 10.06VFTPQTSWGASLMFFLHH122 pKa = 5.87VFYY125 pKa = 10.72GATGTGKK132 pKa = 10.25SRR134 pKa = 11.84LAALRR139 pKa = 11.84CSGRR143 pKa = 11.84RR144 pKa = 11.84VYY146 pKa = 10.52YY147 pKa = 10.24KK148 pKa = 10.53PHH150 pKa = 6.69DD151 pKa = 4.02KK152 pKa = 9.93WWDD155 pKa = 3.69GYY157 pKa = 11.08DD158 pKa = 3.2GHH160 pKa = 6.74EE161 pKa = 4.62CVIIDD166 pKa = 5.35DD167 pKa = 4.65FYY169 pKa = 11.58GWIPYY174 pKa = 10.23DD175 pKa = 3.5EE176 pKa = 5.12LLRR179 pKa = 11.84ITDD182 pKa = 4.37RR183 pKa = 11.84YY184 pKa = 7.42PHH186 pKa = 6.39RR187 pKa = 11.84VAIKK191 pKa = 9.53GAMIQFLAKK200 pKa = 10.3DD201 pKa = 3.61IYY203 pKa = 9.76ITSNKK208 pKa = 9.19HH209 pKa = 4.48PRR211 pKa = 11.84DD212 pKa = 3.62WYY214 pKa = 9.09NHH216 pKa = 5.8LWFQDD221 pKa = 3.36NQYY224 pKa = 11.16AALKK228 pKa = 10.32RR229 pKa = 11.84RR230 pKa = 11.84IDD232 pKa = 3.28EE233 pKa = 4.68HH234 pKa = 7.85ICMGEE239 pKa = 4.04GFNKK243 pKa = 10.11EE244 pKa = 3.89LL245 pKa = 4.27

Molecular weight: 28.68 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A346BLF6|A0A346BLF6_9CIRC Capsid protein OS=Chicken associated cyclovirus 2 OX=2109365 PE=4 SV=1
MM1 pKa = 7.59AFFPRR6 pKa = 11.84RR7 pKa = 11.84RR8 pKa = 11.84RR9 pKa = 11.84LFRR12 pKa = 11.84RR13 pKa = 11.84RR14 pKa = 11.84PRR16 pKa = 11.84YY17 pKa = 8.43NLKK20 pKa = 9.72RR21 pKa = 11.84RR22 pKa = 11.84YY23 pKa = 8.59FRR25 pKa = 11.84RR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84RR29 pKa = 11.84FMRR32 pKa = 11.84SSRR35 pKa = 11.84ATTRR39 pKa = 11.84HH40 pKa = 4.92EE41 pKa = 4.03LSRR44 pKa = 11.84GGQLFTRR51 pKa = 11.84LHH53 pKa = 5.34QSYY56 pKa = 10.16ILNSTTGRR64 pKa = 11.84TIYY67 pKa = 10.23LAPQLQSFTHH77 pKa = 5.0YY78 pKa = 10.26TNFAQFWSSIRR89 pKa = 11.84VWKK92 pKa = 9.92IAYY95 pKa = 8.9KK96 pKa = 7.88ITPVITEE103 pKa = 4.29NVPIDD108 pKa = 3.84NAGATYY114 pKa = 9.99VLSFGRR120 pKa = 11.84HH121 pKa = 4.55VGSIYY126 pKa = 10.78YY127 pKa = 10.14DD128 pKa = 3.51DD129 pKa = 4.41QFPGAANTGVAQSYY143 pKa = 10.36YY144 pKa = 11.0DD145 pKa = 4.23EE146 pKa = 4.93ISNFPNSKK154 pKa = 8.59STSITKK160 pKa = 9.39PLRR163 pKa = 11.84FSFVPKK169 pKa = 9.52TVVNAVGVNGTITGKK184 pKa = 10.4GWVARR189 pKa = 11.84RR190 pKa = 11.84KK191 pKa = 9.67LDD193 pKa = 3.52CDD195 pKa = 3.68TSVGTSLYY203 pKa = 10.52GLVYY207 pKa = 9.99CYY209 pKa = 10.04EE210 pKa = 4.29GQQPEE215 pKa = 4.33STNIQVRR222 pKa = 11.84VDD224 pKa = 3.36CYY226 pKa = 10.68IYY228 pKa = 10.17ATFYY232 pKa = 10.64EE233 pKa = 4.47YY234 pKa = 10.77RR235 pKa = 11.84QFQYY239 pKa = 11.22SPTLEE244 pKa = 4.89KK245 pKa = 9.99IDD247 pKa = 4.47LNKK250 pKa = 9.93MDD252 pKa = 4.76INKK255 pKa = 9.36IDD257 pKa = 3.85DD258 pKa = 4.08KK259 pKa = 10.74KK260 pKa = 9.68TFMM263 pKa = 5.4

Molecular weight: 30.8 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

508

245

263

254.0

29.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.724 ± 0.148

1.772 ± 0.428

5.315 ± 0.768

3.937 ± 0.865

5.512 ± 0.646

7.677 ± 1.339

3.15 ± 1.105

7.283 ± 0.814

5.906 ± 0.653

5.709 ± 0.004

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.575 ± 0.037

4.528 ± 0.282

3.346 ± 0.567

3.74 ± 0.558

9.449 ± 0.813

6.693 ± 0.619

6.299 ± 1.66

4.724 ± 0.922

2.165 ± 0.695

6.496 ± 0.494
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski