Amino acid dipepetide frequency for Tortoise microvirus 76

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.955AlaAla: 6.955 ± 3.828
0.994AlaCys: 0.994 ± 0.794
3.477AlaAsp: 3.477 ± 0.931
5.961AlaGlu: 5.961 ± 1.82
1.987AlaPhe: 1.987 ± 0.786
6.955AlaGly: 6.955 ± 1.518
3.477AlaHis: 3.477 ± 2.291
3.974AlaIle: 3.974 ± 2.032
5.464AlaLys: 5.464 ± 1.696
5.961AlaLeu: 5.961 ± 2.44
0.0AlaMet: 0.0 ± 0.515
3.974AlaAsn: 3.974 ± 1.588
5.464AlaPro: 5.464 ± 1.034
3.477AlaGln: 3.477 ± 0.996
6.458AlaArg: 6.458 ± 1.263
4.471AlaSer: 4.471 ± 1.551
6.458AlaThr: 6.458 ± 3.132
9.439AlaVal: 9.439 ± 2.867
2.981AlaTrp: 2.981 ± 0.922
3.974AlaTyr: 3.974 ± 1.517
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.497CysHis: 0.497 ± 0.397
0.497CysIle: 0.497 ± 0.397
1.987CysLys: 1.987 ± 0.816
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.497CysGln: 0.497 ± 0.574
0.0CysArg: 0.0 ± 0.0
0.497CysSer: 0.497 ± 0.578
0.0CysThr: 0.0 ± 0.0
1.49CysVal: 1.49 ± 0.814
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.471AspAla: 4.471 ± 1.438
0.0AspCys: 0.0 ± 0.0
4.471AspAsp: 4.471 ± 1.13
4.968AspGlu: 4.968 ± 1.597
0.994AspPhe: 0.994 ± 0.563
4.968AspGly: 4.968 ± 1.991
0.497AspHis: 0.497 ± 0.397
1.987AspIle: 1.987 ± 0.707
4.471AspLys: 4.471 ± 1.344
2.484AspLeu: 2.484 ± 1.031
0.994AspMet: 0.994 ± 0.49
1.49AspAsn: 1.49 ± 1.258
5.464AspPro: 5.464 ± 2.417
2.981AspGln: 2.981 ± 1.157
5.464AspArg: 5.464 ± 1.902
0.497AspSer: 0.497 ± 0.505
1.987AspThr: 1.987 ± 1.187
6.955AspVal: 6.955 ± 1.023
1.49AspTrp: 1.49 ± 1.514
1.49AspTyr: 1.49 ± 0.615
0.0AspXaa: 0.0 ± 0.0
Glu
4.968GluAla: 4.968 ± 1.306
0.0GluCys: 0.0 ± 0.0
4.471GluAsp: 4.471 ± 2.42
1.987GluGlu: 1.987 ± 0.952
1.49GluPhe: 1.49 ± 0.947
3.477GluGly: 3.477 ± 0.822
0.497GluHis: 0.497 ± 0.349
3.974GluIle: 3.974 ± 3.481
2.981GluLys: 2.981 ± 1.221
3.477GluLeu: 3.477 ± 1.195
1.49GluMet: 1.49 ± 0.72
1.987GluAsn: 1.987 ± 1.286
0.994GluPro: 0.994 ± 0.581
3.974GluGln: 3.974 ± 1.614
7.452GluArg: 7.452 ± 2.35
2.484GluSer: 2.484 ± 0.835
3.974GluThr: 3.974 ± 0.958
1.49GluVal: 1.49 ± 0.72
2.484GluTrp: 2.484 ± 1.135
1.49GluTyr: 1.49 ± 0.785
0.0GluXaa: 0.0 ± 0.0
Phe
2.484PheAla: 2.484 ± 1.114
0.0PheCys: 0.0 ± 0.0
1.49PheAsp: 1.49 ± 0.786
2.981PheGlu: 2.981 ± 0.991
1.49PhePhe: 1.49 ± 0.72
3.974PheGly: 3.974 ± 0.949
0.0PheHis: 0.0 ± 0.0
0.994PheIle: 0.994 ± 0.465
0.497PheLys: 0.497 ± 0.397
3.477PheLeu: 3.477 ± 1.475
0.0PheMet: 0.0 ± 0.0
1.49PheAsn: 1.49 ± 0.613
1.49PhePro: 1.49 ± 0.51
1.987PheGln: 1.987 ± 0.991
1.49PheArg: 1.49 ± 0.814
2.484PheSer: 2.484 ± 0.965
0.497PheThr: 0.497 ± 0.349
2.484PheVal: 2.484 ± 1.085
1.49PheTrp: 1.49 ± 0.51
0.994PheTyr: 0.994 ± 0.593
0.0PheXaa: 0.0 ± 0.0
Gly
8.942GlyAla: 8.942 ± 3.222
0.0GlyCys: 0.0 ± 0.0
3.477GlyAsp: 3.477 ± 1.777
3.974GlyGlu: 3.974 ± 2.153
2.981GlyPhe: 2.981 ± 0.77
15.897GlyGly: 15.897 ± 7.803
0.497GlyHis: 0.497 ± 0.507
5.464GlyIle: 5.464 ± 1.656
8.942GlyLys: 8.942 ± 3.03
6.955GlyLeu: 6.955 ± 1.566
1.49GlyMet: 1.49 ± 0.615
5.464GlyAsn: 5.464 ± 1.782
7.948GlyPro: 7.948 ± 3.785
3.974GlyGln: 3.974 ± 0.696
5.961GlyArg: 5.961 ± 2.202
6.458GlySer: 6.458 ± 2.38
5.961GlyThr: 5.961 ± 3.13
4.968GlyVal: 4.968 ± 2.304
0.994GlyTrp: 0.994 ± 0.754
2.981GlyTyr: 2.981 ± 1.472
0.0GlyXaa: 0.0 ± 0.0
His
0.994HisAla: 0.994 ± 0.714
0.994HisCys: 0.994 ± 0.55
0.497HisAsp: 0.497 ± 0.505
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
3.477HisGly: 3.477 ± 1.013
0.0HisHis: 0.0 ± 0.0
0.497HisIle: 0.497 ± 0.349
0.497HisLys: 0.497 ± 0.397
0.994HisLeu: 0.994 ± 0.675
0.497HisMet: 0.497 ± 0.507
1.49HisAsn: 1.49 ± 0.882
0.994HisPro: 0.994 ± 0.55
0.497HisGln: 0.497 ± 0.681
0.497HisArg: 0.497 ± 0.578
2.484HisSer: 2.484 ± 0.707
0.497HisThr: 0.497 ± 0.681
0.0HisVal: 0.0 ± 0.0
1.49HisTrp: 1.49 ± 0.615
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.968IleAla: 4.968 ± 1.575
0.0IleCys: 0.0 ± 0.0
2.484IleAsp: 2.484 ± 1.031
2.981IleGlu: 2.981 ± 1.405
0.0IlePhe: 0.0 ± 0.0
4.471IleGly: 4.471 ± 1.936
1.987IleHis: 1.987 ± 0.913
1.987IleIle: 1.987 ± 0.913
1.49IleLys: 1.49 ± 0.791
2.484IleLeu: 2.484 ± 1.409
0.497IleMet: 0.497 ± 0.349
1.987IleAsn: 1.987 ± 0.475
0.994IlePro: 0.994 ± 0.593
0.994IleGln: 0.994 ± 0.593
1.49IleArg: 1.49 ± 0.814
2.484IleSer: 2.484 ± 0.95
0.994IleThr: 0.994 ± 0.794
4.471IleVal: 4.471 ± 1.584
1.49IleTrp: 1.49 ± 0.786
0.497IleTyr: 0.497 ± 0.397
0.0IleXaa: 0.0 ± 0.0
Lys
5.464LysAla: 5.464 ± 1.656
0.994LysCys: 0.994 ± 0.563
2.981LysAsp: 2.981 ± 0.527
1.987LysGlu: 1.987 ± 0.687
3.974LysPhe: 3.974 ± 1.437
6.955LysGly: 6.955 ± 1.972
0.497LysHis: 0.497 ± 0.507
1.987LysIle: 1.987 ± 0.87
2.981LysLys: 2.981 ± 1.167
2.981LysLeu: 2.981 ± 1.168
1.987LysMet: 1.987 ± 0.935
1.987LysAsn: 1.987 ± 0.894
7.452LysPro: 7.452 ± 4.475
1.987LysGln: 1.987 ± 1.267
3.477LysArg: 3.477 ± 1.949
0.0LysSer: 0.0 ± 0.0
3.477LysThr: 3.477 ± 0.79
3.477LysVal: 3.477 ± 0.933
0.497LysTrp: 0.497 ± 0.397
2.981LysTyr: 2.981 ± 1.489
0.0LysXaa: 0.0 ± 0.0
Leu
5.464LeuAla: 5.464 ± 1.599
0.0LeuCys: 0.0 ± 0.0
4.471LeuAsp: 4.471 ± 1.803
3.477LeuGlu: 3.477 ± 1.713
1.49LeuPhe: 1.49 ± 0.615
4.968LeuGly: 4.968 ± 1.527
0.497LeuHis: 0.497 ± 0.681
1.987LeuIle: 1.987 ± 1.185
4.471LeuLys: 4.471 ± 1.737
4.968LeuLeu: 4.968 ± 2.726
2.484LeuMet: 2.484 ± 1.036
5.961LeuAsn: 5.961 ± 1.524
3.477LeuPro: 3.477 ± 0.6
1.987LeuGln: 1.987 ± 0.603
4.968LeuArg: 4.968 ± 1.344
4.471LeuSer: 4.471 ± 1.692
3.974LeuThr: 3.974 ± 1.878
3.974LeuVal: 3.974 ± 1.107
0.994LeuTrp: 0.994 ± 0.675
0.497LeuTyr: 0.497 ± 0.349
0.0LeuXaa: 0.0 ± 0.0
Met
3.477MetAla: 3.477 ± 1.42
0.497MetCys: 0.497 ± 0.397
0.994MetAsp: 0.994 ± 0.697
0.994MetGlu: 0.994 ± 0.49
0.0MetPhe: 0.0 ± 0.0
1.49MetGly: 1.49 ± 0.681
0.994MetHis: 0.994 ± 0.465
0.994MetIle: 0.994 ± 0.581
0.0MetLys: 0.0 ± 0.0
0.497MetLeu: 0.497 ± 0.349
0.994MetMet: 0.994 ± 0.697
2.484MetAsn: 2.484 ± 0.656
0.994MetPro: 0.994 ± 0.49
1.987MetGln: 1.987 ± 1.181
0.994MetArg: 0.994 ± 0.675
1.49MetSer: 1.49 ± 0.737
0.0MetThr: 0.0 ± 0.0
1.987MetVal: 1.987 ± 1.193
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.974AsnAla: 3.974 ± 1.084
0.0AsnCys: 0.0 ± 0.0
2.981AsnAsp: 2.981 ± 0.865
0.994AsnGlu: 0.994 ± 0.593
1.49AsnPhe: 1.49 ± 0.882
3.477AsnGly: 3.477 ± 0.7
1.987AsnHis: 1.987 ± 1.09
2.981AsnIle: 2.981 ± 0.86
1.987AsnLys: 1.987 ± 0.603
4.471AsnLeu: 4.471 ± 1.454
0.497AsnMet: 0.497 ± 0.574
1.987AsnAsn: 1.987 ± 0.816
5.961AsnPro: 5.961 ± 0.943
0.994AsnGln: 0.994 ± 0.49
5.464AsnArg: 5.464 ± 1.241
3.477AsnSer: 3.477 ± 1.059
1.49AsnThr: 1.49 ± 0.613
1.987AsnVal: 1.987 ± 0.652
0.994AsnTrp: 0.994 ± 0.754
1.49AsnTyr: 1.49 ± 1.217
0.0AsnXaa: 0.0 ± 0.0
Pro
7.452ProAla: 7.452 ± 2.468
0.497ProCys: 0.497 ± 0.505
2.484ProAsp: 2.484 ± 0.937
3.477ProGlu: 3.477 ± 0.919
2.981ProPhe: 2.981 ± 1.274
6.458ProGly: 6.458 ± 5.4
0.497ProHis: 0.497 ± 0.578
1.987ProIle: 1.987 ± 0.93
1.987ProLys: 1.987 ± 0.475
4.968ProLeu: 4.968 ± 1.25
2.484ProMet: 2.484 ± 1.336
2.981ProAsn: 2.981 ± 1.907
3.974ProPro: 3.974 ± 1.573
1.987ProGln: 1.987 ± 1.163
4.968ProArg: 4.968 ± 1.774
6.458ProSer: 6.458 ± 3.697
4.968ProThr: 4.968 ± 1.005
3.477ProVal: 3.477 ± 1.291
1.49ProTrp: 1.49 ± 0.796
1.987ProTyr: 1.987 ± 1.102
0.0ProXaa: 0.0 ± 0.0
Gln
6.955GlnAla: 6.955 ± 1.902
0.497GlnCys: 0.497 ± 0.397
3.477GlnAsp: 3.477 ± 1.478
3.974GlnGlu: 3.974 ± 1.353
2.484GlnPhe: 2.484 ± 1.076
3.974GlnGly: 3.974 ± 1.635
0.497GlnHis: 0.497 ± 0.397
1.987GlnIle: 1.987 ± 1.061
1.987GlnLys: 1.987 ± 0.822
3.477GlnLeu: 3.477 ± 1.476
0.497GlnMet: 0.497 ± 0.681
0.994GlnAsn: 0.994 ± 0.563
3.974GlnPro: 3.974 ± 1.752
2.484GlnGln: 2.484 ± 1.053
3.974GlnArg: 3.974 ± 0.696
0.994GlnSer: 0.994 ± 0.63
2.484GlnThr: 2.484 ± 1.116
1.49GlnVal: 1.49 ± 0.51
0.497GlnTrp: 0.497 ± 0.505
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.974ArgAla: 3.974 ± 0.889
0.497ArgCys: 0.497 ± 0.574
5.464ArgAsp: 5.464 ± 1.894
5.961ArgGlu: 5.961 ± 2.282
2.484ArgPhe: 2.484 ± 0.966
4.471ArgGly: 4.471 ± 1.936
0.497ArgHis: 0.497 ± 0.681
1.987ArgIle: 1.987 ± 0.652
4.471ArgLys: 4.471 ± 1.617
4.968ArgLeu: 4.968 ± 1.326
1.49ArgMet: 1.49 ± 0.791
1.987ArgAsn: 1.987 ± 1.102
5.961ArgPro: 5.961 ± 2.859
4.471ArgGln: 4.471 ± 1.254
3.974ArgArg: 3.974 ± 1.739
4.968ArgSer: 4.968 ± 1.277
2.981ArgThr: 2.981 ± 0.92
5.464ArgVal: 5.464 ± 1.499
1.987ArgTrp: 1.987 ± 0.705
1.987ArgTyr: 1.987 ± 0.93
0.0ArgXaa: 0.0 ± 0.0
Ser
7.452SerAla: 7.452 ± 1.583
0.0SerCys: 0.0 ± 0.0
3.974SerAsp: 3.974 ± 0.547
1.987SerGlu: 1.987 ± 1.441
0.994SerPhe: 0.994 ± 0.581
10.432SerGly: 10.432 ± 3.843
0.0SerHis: 0.0 ± 0.0
0.994SerIle: 0.994 ± 0.731
2.981SerLys: 2.981 ± 0.912
1.987SerLeu: 1.987 ± 1.031
1.49SerMet: 1.49 ± 0.737
1.49SerAsn: 1.49 ± 0.617
3.477SerPro: 3.477 ± 1.856
3.477SerGln: 3.477 ± 1.068
2.484SerArg: 2.484 ± 0.747
0.994SerSer: 0.994 ± 0.731
3.974SerThr: 3.974 ± 2.181
3.477SerVal: 3.477 ± 0.98
0.0SerTrp: 0.0 ± 0.0
1.987SerTyr: 1.987 ± 0.901
0.0SerXaa: 0.0 ± 0.0
Thr
4.968ThrAla: 4.968 ± 1.407
0.0ThrCys: 0.0 ± 0.0
1.987ThrAsp: 1.987 ± 1.187
2.981ThrGlu: 2.981 ± 0.631
1.49ThrPhe: 1.49 ± 0.716
5.961ThrGly: 5.961 ± 2.545
1.987ThrHis: 1.987 ± 0.816
0.994ThrIle: 0.994 ± 0.593
2.981ThrLys: 2.981 ± 0.929
2.981ThrLeu: 2.981 ± 1.268
0.0ThrMet: 0.0 ± 0.0
2.981ThrAsn: 2.981 ± 1.206
3.477ThrPro: 3.477 ± 0.921
4.471ThrGln: 4.471 ± 1.663
4.471ThrArg: 4.471 ± 1.995
1.987ThrSer: 1.987 ± 0.799
4.471ThrThr: 4.471 ± 1.1
2.981ThrVal: 2.981 ± 1.361
0.0ThrTrp: 0.0 ± 0.0
1.49ThrTyr: 1.49 ± 0.814
0.0ThrXaa: 0.0 ± 0.0
Val
3.974ValAla: 3.974 ± 1.09
0.0ValCys: 0.0 ± 0.0
5.961ValAsp: 5.961 ± 1.31
4.968ValGlu: 4.968 ± 1.541
3.974ValPhe: 3.974 ± 0.88
7.452ValGly: 7.452 ± 2.277
0.0ValHis: 0.0 ± 0.0
2.484ValIle: 2.484 ± 1.116
4.968ValLys: 4.968 ± 1.738
3.477ValLeu: 3.477 ± 1.692
0.994ValMet: 0.994 ± 0.697
4.968ValAsn: 4.968 ± 1.765
4.471ValPro: 4.471 ± 2.059
1.49ValGln: 1.49 ± 0.588
5.464ValArg: 5.464 ± 1.241
2.981ValSer: 2.981 ± 0.996
4.471ValThr: 4.471 ± 1.137
2.981ValVal: 2.981 ± 0.92
1.49ValTrp: 1.49 ± 1.115
0.994ValTyr: 0.994 ± 0.697
0.0ValXaa: 0.0 ± 0.0
Trp
2.484TrpAla: 2.484 ± 0.835
0.497TrpCys: 0.497 ± 0.578
1.49TrpAsp: 1.49 ± 0.814
1.49TrpGlu: 1.49 ± 0.981
0.994TrpPhe: 0.994 ± 0.465
2.484TrpGly: 2.484 ± 1.513
0.994TrpHis: 0.994 ± 0.675
0.0TrpIle: 0.0 ± 0.0
0.497TrpLys: 0.497 ± 0.507
1.987TrpLeu: 1.987 ± 0.771
0.994TrpMet: 0.994 ± 0.736
0.994TrpAsn: 0.994 ± 0.697
0.497TrpPro: 0.497 ± 0.349
0.497TrpGln: 0.497 ± 0.507
0.994TrpArg: 0.994 ± 1.009
1.987TrpSer: 1.987 ± 1.102
0.0TrpThr: 0.0 ± 0.0
1.49TrpVal: 1.49 ± 1.077
1.49TrpTrp: 1.49 ± 0.51
0.994TrpTyr: 0.994 ± 0.581
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.981TyrAla: 2.981 ± 1.021
0.0TyrCys: 0.0 ± 0.0
1.49TyrAsp: 1.49 ± 1.217
0.0TyrGlu: 0.0 ± 0.0
0.497TyrPhe: 0.497 ± 0.397
1.987TyrGly: 1.987 ± 1.031
0.497TyrHis: 0.497 ± 0.397
0.994TyrIle: 0.994 ± 0.465
2.484TyrLys: 2.484 ± 0.974
1.987TyrLeu: 1.987 ± 0.901
1.49TyrMet: 1.49 ± 0.685
1.987TyrAsn: 1.987 ± 0.686
0.497TyrPro: 0.497 ± 0.507
2.484TyrGln: 2.484 ± 1.466
0.0TyrArg: 0.0 ± 0.0
1.987TyrSer: 1.987 ± 1.204
0.0TyrThr: 0.0 ± 0.0
3.477TyrVal: 3.477 ± 1.147
0.994TyrTrp: 0.994 ± 0.794
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2014 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski