Amino acid dipepetide frequency for Jeotgalibacillus sp. R-1-5s-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.169AlaAla: 7.169 ± 0.121	0.545AlaCys: 0.545 ± 0.027	4.251AlaAsp: 4.251 ± 0.07	5.773AlaGlu: 5.773 ± 0.091	3.684AlaPhe: 3.684 ± 0.07	6.481AlaGly: 6.481 ± 0.09	1.383AlaHis: 1.383 ± 0.045	5.507AlaIle: 5.507 ± 0.088	4.065AlaLys: 4.065 ± 0.077	7.542AlaLeu: 7.542 ± 0.092	2.214AlaMet: 2.214 ± 0.054	2.315AlaAsn: 2.315 ± 0.053	2.161AlaPro: 2.161 ± 0.05	2.278AlaGln: 2.278 ± 0.057	2.91AlaArg: 2.91 ± 0.054	4.403AlaSer: 4.403 ± 0.076	3.272AlaThr: 3.272 ± 0.061	6.407AlaVal: 6.407 ± 0.086	0.674AlaTrp: 0.674 ± 0.029	2.381AlaTyr: 2.381 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.376CysAla: 0.376 ± 0.02	0.078CysCys: 0.078 ± 0.009	0.366CysAsp: 0.366 ± 0.018	0.414CysGlu: 0.414 ± 0.02	0.243CysPhe: 0.243 ± 0.014	0.597CysGly: 0.597 ± 0.028	0.199CysHis: 0.199 ± 0.014	0.417CysIle: 0.417 ± 0.022	0.295CysLys: 0.295 ± 0.019	0.578CysLeu: 0.578 ± 0.023	0.155CysMet: 0.155 ± 0.014	0.214CysAsn: 0.214 ± 0.015	0.343CysPro: 0.343 ± 0.017	0.222CysGln: 0.222 ± 0.015	0.286CysArg: 0.286 ± 0.016	0.459CysSer: 0.459 ± 0.022	0.35CysThr: 0.35 ± 0.018	0.385CysVal: 0.385 ± 0.021	0.057CysTrp: 0.057 ± 0.007	0.222CysTyr: 0.222 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.603AspAla: 3.603 ± 0.075	0.35AspCys: 0.35 ± 0.02	2.682AspAsp: 2.682 ± 0.059	4.985AspGlu: 4.985 ± 0.092	2.52AspPhe: 2.52 ± 0.053	3.696AspGly: 3.696 ± 0.057	1.473AspHis: 1.473 ± 0.041	3.726AspIle: 3.726 ± 0.067	2.51AspLys: 2.51 ± 0.045	5.476AspLeu: 5.476 ± 0.074	1.392AspMet: 1.392 ± 0.038	1.455AspAsn: 1.455 ± 0.041	2.258AspPro: 2.258 ± 0.052	3.041AspGln: 3.041 ± 0.055	2.853AspArg: 2.853 ± 0.058	2.83AspSer: 2.83 ± 0.05	2.377AspThr: 2.377 ± 0.045	3.884AspVal: 3.884 ± 0.069	0.673AspTrp: 0.673 ± 0.029	2.312AspTyr: 2.312 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	6.198GluAla: 6.198 ± 0.099	0.355GluCys: 0.355 ± 0.02	4.214GluAsp: 4.214 ± 0.069	7.936GluGlu: 7.936 ± 0.124	2.575GluPhe: 2.575 ± 0.06	4.873GluGly: 4.873 ± 0.08	1.673GluHis: 1.673 ± 0.037	5.37GluIle: 5.37 ± 0.075	6.184GluLys: 6.184 ± 0.085	7.589GluLeu: 7.589 ± 0.107	2.465GluMet: 2.465 ± 0.057	3.347GluAsn: 3.347 ± 0.064	2.273GluPro: 2.273 ± 0.052	3.695GluGln: 3.695 ± 0.064	3.94GluArg: 3.94 ± 0.072	4.07GluSer: 4.07 ± 0.073	4.321GluThr: 4.321 ± 0.074	5.277GluVal: 5.277 ± 0.075	1.021GluTrp: 1.021 ± 0.031	2.171GluTyr: 2.171 ± 0.054	0.0GluXaa: 0.0 ± 0.0
Phe	3.114PheAla: 3.114 ± 0.067	0.335PheCys: 0.335 ± 0.019	2.577PheAsp: 2.577 ± 0.052	3.025PheGlu: 3.025 ± 0.063	2.288PhePhe: 2.288 ± 0.06	3.271PheGly: 3.271 ± 0.063	0.99PheHis: 0.99 ± 0.034	3.622PheIle: 3.622 ± 0.065	2.231PheLys: 2.231 ± 0.048	4.368PheLeu: 4.368 ± 0.077	1.216PheMet: 1.216 ± 0.03	1.873PheAsn: 1.873 ± 0.044	1.644PhePro: 1.644 ± 0.043	1.529PheGln: 1.529 ± 0.038	1.736PheArg: 1.736 ± 0.04	3.364PheSer: 3.364 ± 0.07	2.76PheThr: 2.76 ± 0.056	3.059PheVal: 3.059 ± 0.067	0.454PheTrp: 0.454 ± 0.023	1.761PheTyr: 1.761 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	5.207GlyAla: 5.207 ± 0.08	0.534GlyCys: 0.534 ± 0.024	3.567GlyAsp: 3.567 ± 0.069	5.023GlyGlu: 5.023 ± 0.081	3.517GlyPhe: 3.517 ± 0.069	4.964GlyGly: 4.964 ± 0.077	1.458GlyHis: 1.458 ± 0.041	5.496GlyIle: 5.496 ± 0.079	4.436GlyLys: 4.436 ± 0.079	6.895GlyLeu: 6.895 ± 0.096	2.195GlyMet: 2.195 ± 0.049	2.473GlyAsn: 2.473 ± 0.052	1.761GlyPro: 1.761 ± 0.043	2.39GlyGln: 2.39 ± 0.053	2.92GlyArg: 2.92 ± 0.061	4.27GlySer: 4.27 ± 0.063	4.147GlyThr: 4.147 ± 0.071	5.153GlyVal: 5.153 ± 0.083	0.885GlyTrp: 0.885 ± 0.032	2.782GlyTyr: 2.782 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.458HisAla: 1.458 ± 0.047	0.188HisCys: 0.188 ± 0.014	1.228HisAsp: 1.228 ± 0.036	1.603HisGlu: 1.603 ± 0.044	1.083HisPhe: 1.083 ± 0.032	1.475HisGly: 1.475 ± 0.044	0.753HisHis: 0.753 ± 0.028	1.375HisIle: 1.375 ± 0.045	0.981HisLys: 0.981 ± 0.031	2.252HisLeu: 2.252 ± 0.052	0.503HisMet: 0.503 ± 0.021	0.751HisAsn: 0.751 ± 0.029	1.203HisPro: 1.203 ± 0.039	1.002HisGln: 1.002 ± 0.037	0.937HisArg: 0.937 ± 0.035	1.25HisSer: 1.25 ± 0.034	1.085HisThr: 1.085 ± 0.035	1.497HisVal: 1.497 ± 0.041	0.23HisTrp: 0.23 ± 0.018	0.903HisTyr: 0.903 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.849IleAla: 5.849 ± 0.089	0.5IleCys: 0.5 ± 0.019	4.05IleAsp: 4.05 ± 0.067	5.695IleGlu: 5.695 ± 0.068	2.925IlePhe: 2.925 ± 0.068	5.426IleGly: 5.426 ± 0.087	1.722IleHis: 1.722 ± 0.045	4.878IleIle: 4.878 ± 0.097	3.868IleLys: 3.868 ± 0.064	6.598IleLeu: 6.598 ± 0.102	1.682IleMet: 1.682 ± 0.047	2.67IleAsn: 2.67 ± 0.051	3.083IlePro: 3.083 ± 0.055	2.973IleGln: 2.973 ± 0.057	3.4IleArg: 3.4 ± 0.056	4.666IleSer: 4.666 ± 0.075	4.166IleThr: 4.166 ± 0.07	5.0IleVal: 5.0 ± 0.071	0.647IleTrp: 0.647 ± 0.029	2.228IleTyr: 2.228 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	4.534LysAla: 4.534 ± 0.07	0.256LysCys: 0.256 ± 0.017	3.323LysAsp: 3.323 ± 0.058	6.088LysGlu: 6.088 ± 0.102	1.515LysPhe: 1.515 ± 0.038	4.145LysGly: 4.145 ± 0.063	1.196LysHis: 1.196 ± 0.039	3.688LysIle: 3.688 ± 0.075	5.405LysLys: 5.405 ± 0.091	5.082LysLeu: 5.082 ± 0.081	2.111LysMet: 2.111 ± 0.048	2.675LysAsn: 2.675 ± 0.059	2.125LysPro: 2.125 ± 0.052	2.631LysGln: 2.631 ± 0.059	3.176LysArg: 3.176 ± 0.053	3.242LysSer: 3.242 ± 0.056	3.391LysThr: 3.391 ± 0.066	4.02LysVal: 4.02 ± 0.064	0.817LysTrp: 0.817 ± 0.029	1.612LysTyr: 1.612 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	7.474LeuAla: 7.474 ± 0.107	0.59LeuCys: 0.59 ± 0.024	4.941LeuAsp: 4.941 ± 0.08	6.683LeuGlu: 6.683 ± 0.088	4.825LeuPhe: 4.825 ± 0.088	6.031LeuGly: 6.031 ± 0.093	2.04LeuHis: 2.04 ± 0.045	7.458LeuIle: 7.458 ± 0.1	6.235LeuLys: 6.235 ± 0.088	10.031LeuLeu: 10.031 ± 0.135	2.653LeuMet: 2.653 ± 0.05	4.288LeuAsn: 4.288 ± 0.076	3.904LeuPro: 3.904 ± 0.068	3.492LeuGln: 3.492 ± 0.074	3.697LeuArg: 3.697 ± 0.067	7.035LeuSer: 7.035 ± 0.09	6.018LeuThr: 6.018 ± 0.07	6.16LeuVal: 6.16 ± 0.083	0.807LeuTrp: 0.807 ± 0.028	3.164LeuTyr: 3.164 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.103MetAla: 2.103 ± 0.045	0.141MetCys: 0.141 ± 0.013	1.6MetAsp: 1.6 ± 0.045	2.066MetGlu: 2.066 ± 0.043	1.057MetPhe: 1.057 ± 0.038	1.724MetGly: 1.724 ± 0.041	0.483MetHis: 0.483 ± 0.02	2.459MetIle: 2.459 ± 0.045	2.479MetLys: 2.479 ± 0.047	2.578MetLeu: 2.578 ± 0.053	1.021MetMet: 1.021 ± 0.039	1.639MetAsn: 1.639 ± 0.039	1.01MetPro: 1.01 ± 0.035	0.925MetGln: 0.925 ± 0.031	1.208MetArg: 1.208 ± 0.037	1.768MetSer: 1.768 ± 0.037	1.955MetThr: 1.955 ± 0.044	1.784MetVal: 1.784 ± 0.046	0.194MetTrp: 0.194 ± 0.013	0.668MetTyr: 0.668 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.726AsnAla: 2.726 ± 0.051	0.226AsnCys: 0.226 ± 0.016	2.199AsnAsp: 2.199 ± 0.043	3.554AsnGlu: 3.554 ± 0.06	1.343AsnPhe: 1.343 ± 0.041	3.159AsnGly: 3.159 ± 0.067	0.917AsnHis: 0.917 ± 0.03	2.612AsnIle: 2.612 ± 0.051	2.1AsnLys: 2.1 ± 0.048	3.367AsnLeu: 3.367 ± 0.053	1.043AsnMet: 1.043 ± 0.034	1.465AsnAsn: 1.465 ± 0.046	1.967AsnPro: 1.967 ± 0.049	1.776AsnGln: 1.776 ± 0.043	2.135AsnArg: 2.135 ± 0.041	1.843AsnSer: 1.843 ± 0.042	1.898AsnThr: 1.898 ± 0.04	2.691AsnVal: 2.691 ± 0.058	0.441AsnTrp: 0.441 ± 0.019	1.11AsnTyr: 1.11 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.87ProAla: 2.87 ± 0.062	0.202ProCys: 0.202 ± 0.015	2.541ProAsp: 2.541 ± 0.056	3.534ProGlu: 3.534 ± 0.066	2.062ProPhe: 2.062 ± 0.05	2.548ProGly: 2.548 ± 0.051	0.81ProHis: 0.81 ± 0.029	2.234ProIle: 2.234 ± 0.05	1.703ProLys: 1.703 ± 0.043	3.552ProLeu: 3.552 ± 0.068	0.851ProMet: 0.851 ± 0.027	1.259ProAsn: 1.259 ± 0.029	0.996ProPro: 0.996 ± 0.038	1.026ProGln: 1.026 ± 0.036	1.092ProArg: 1.092 ± 0.034	2.377ProSer: 2.377 ± 0.053	1.562ProThr: 1.562 ± 0.04	3.449ProVal: 3.449 ± 0.067	0.382ProTrp: 0.382 ± 0.021	1.352ProTyr: 1.352 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.088GlnAla: 3.088 ± 0.058	0.174GlnCys: 0.174 ± 0.014	1.91GlnAsp: 1.91 ± 0.042	3.053GlnGlu: 3.053 ± 0.063	1.713GlnPhe: 1.713 ± 0.045	2.226GlnGly: 2.226 ± 0.045	0.877GlnHis: 0.877 ± 0.028	2.45GlnIle: 2.45 ± 0.056	2.624GlnLys: 2.624 ± 0.053	4.075GlnLeu: 4.075 ± 0.064	1.185GlnMet: 1.185 ± 0.038	1.488GlnAsn: 1.488 ± 0.04	1.365GlnPro: 1.365 ± 0.04	1.861GlnGln: 1.861 ± 0.047	1.6GlnArg: 1.6 ± 0.04	2.552GlnSer: 2.552 ± 0.056	2.207GlnThr: 2.207 ± 0.053	2.37GlnVal: 2.37 ± 0.044	0.457GlnTrp: 0.457 ± 0.02	1.314GlnTyr: 1.314 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.758ArgAla: 2.758 ± 0.058	0.25ArgCys: 0.25 ± 0.017	2.39ArgAsp: 2.39 ± 0.046	3.579ArgGlu: 3.579 ± 0.059	2.173ArgPhe: 2.173 ± 0.052	2.52ArgGly: 2.52 ± 0.049	0.969ArgHis: 0.969 ± 0.032	3.121ArgIle: 3.121 ± 0.06	3.175ArgLys: 3.175 ± 0.056	4.377ArgLeu: 4.377 ± 0.061	1.458ArgMet: 1.458 ± 0.044	1.821ArgAsn: 1.821 ± 0.045	1.432ArgPro: 1.432 ± 0.035	1.808ArgGln: 1.808 ± 0.04	2.024ArgArg: 2.024 ± 0.058	2.637ArgSer: 2.637 ± 0.048	2.218ArgThr: 2.218 ± 0.053	2.911ArgVal: 2.911 ± 0.058	0.441ArgTrp: 0.441 ± 0.022	1.571ArgTyr: 1.571 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.402SerAla: 4.402 ± 0.079	0.353SerCys: 0.353 ± 0.019	3.134SerAsp: 3.134 ± 0.063	4.326SerGlu: 4.326 ± 0.075	3.445SerPhe: 3.445 ± 0.066	4.998SerGly: 4.998 ± 0.076	1.213SerHis: 1.213 ± 0.036	4.824SerIle: 4.824 ± 0.077	3.23SerLys: 3.23 ± 0.062	6.176SerLeu: 6.176 ± 0.081	1.947SerMet: 1.947 ± 0.044	2.128SerAsn: 2.128 ± 0.048	2.193SerPro: 2.193 ± 0.049	2.046SerGln: 2.046 ± 0.045	2.604SerArg: 2.604 ± 0.047	4.069SerSer: 4.069 ± 0.073	3.07SerThr: 3.07 ± 0.059	4.743SerVal: 4.743 ± 0.065	0.64SerTrp: 0.64 ± 0.032	2.137SerTyr: 2.137 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.76ThrAla: 4.76 ± 0.062	0.327ThrCys: 0.327 ± 0.02	3.043ThrAsp: 3.043 ± 0.053	3.968ThrGlu: 3.968 ± 0.078	2.604ThrPhe: 2.604 ± 0.052	4.681ThrGly: 4.681 ± 0.074	1.063ThrHis: 1.063 ± 0.033	4.2ThrIle: 4.2 ± 0.077	2.637ThrLys: 2.637 ± 0.055	5.204ThrLeu: 5.204 ± 0.073	1.318ThrMet: 1.318 ± 0.034	1.996ThrAsn: 1.996 ± 0.043	2.301ThrPro: 2.301 ± 0.04	1.477ThrGln: 1.477 ± 0.039	1.931ThrArg: 1.931 ± 0.044	3.287ThrSer: 3.287 ± 0.052	2.681ThrThr: 2.681 ± 0.054	4.602ThrVal: 4.602 ± 0.076	0.465ThrTrp: 0.465 ± 0.022	1.859ThrTyr: 1.859 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.921ValAla: 4.921 ± 0.078	0.525ValCys: 0.525 ± 0.023	3.568ValAsp: 3.568 ± 0.062	5.008ValGlu: 5.008 ± 0.081	3.296ValPhe: 3.296 ± 0.068	4.203ValGly: 4.203 ± 0.072	1.477ValHis: 1.477 ± 0.04	5.618ValIle: 5.618 ± 0.086	4.552ValLys: 4.552 ± 0.07	7.234ValLeu: 7.234 ± 0.092	2.21ValMet: 2.21 ± 0.05	3.026ValAsn: 3.026 ± 0.051	2.739ValPro: 2.739 ± 0.049	2.529ValGln: 2.529 ± 0.053	2.991ValArg: 2.991 ± 0.056	4.8ValSer: 4.8 ± 0.063	4.481ValThr: 4.481 ± 0.082	4.804ValVal: 4.804 ± 0.08	0.703ValTrp: 0.703 ± 0.027	2.279ValTyr: 2.279 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.625TrpAla: 0.625 ± 0.027	0.081TrpCys: 0.081 ± 0.009	0.535TrpAsp: 0.535 ± 0.027	0.657TrpGlu: 0.657 ± 0.028	0.521TrpPhe: 0.521 ± 0.023	0.695TrpGly: 0.695 ± 0.027	0.219TrpHis: 0.219 ± 0.016	0.906TrpIle: 0.906 ± 0.034	0.647TrpLys: 0.647 ± 0.028	1.218TrpLeu: 1.218 ± 0.037	0.44TrpMet: 0.44 ± 0.019	0.491TrpAsn: 0.491 ± 0.024	0.294TrpPro: 0.294 ± 0.022	0.385TrpGln: 0.385 ± 0.019	0.434TrpArg: 0.434 ± 0.021	0.63TrpSer: 0.63 ± 0.026	0.627TrpThr: 0.627 ± 0.025	0.663TrpVal: 0.663 ± 0.026	0.15TrpTrp: 0.15 ± 0.013	0.314TrpTyr: 0.314 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.181TyrAla: 2.181 ± 0.046	0.244TyrCys: 0.244 ± 0.015	1.975TyrAsp: 1.975 ± 0.045	2.577TyrGlu: 2.577 ± 0.062	1.826TyrPhe: 1.826 ± 0.046	2.362TyrGly: 2.362 ± 0.054	0.841TyrHis: 0.841 ± 0.029	2.066TyrIle: 2.066 ± 0.051	1.675TyrLys: 1.675 ± 0.044	3.334TyrLeu: 3.334 ± 0.066	0.802TyrMet: 0.802 ± 0.027	1.2TyrAsn: 1.2 ± 0.033	1.351TyrPro: 1.351 ± 0.038	1.504TyrGln: 1.504 ± 0.04	1.76TyrArg: 1.76 ± 0.043	2.126TyrSer: 2.126 ± 0.043	1.818TyrThr: 1.818 ± 0.042	2.106TyrVal: 2.106 ± 0.044	0.394TyrTrp: 0.394 ± 0.021	1.285TyrTyr: 1.285 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3369 proteins (982630 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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