Amino acid dipepetide frequency for Chrysochromulina tobinii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.848AlaAla: 21.848 ± 0.146	1.87AlaCys: 1.87 ± 0.017	6.336AlaAsp: 6.336 ± 0.032	9.209AlaGlu: 9.209 ± 0.073	3.701AlaPhe: 3.701 ± 0.022	8.311AlaGly: 8.311 ± 0.051	2.845AlaHis: 2.845 ± 0.029	4.515AlaIle: 4.515 ± 0.03	5.42AlaLys: 5.42 ± 0.042	13.501AlaLeu: 13.501 ± 0.063	2.988AlaMet: 2.988 ± 0.024	2.833AlaAsn: 2.833 ± 0.018	7.017AlaPro: 7.017 ± 0.05	4.57AlaGln: 4.57 ± 0.037	8.455AlaArg: 8.455 ± 0.053	9.304AlaSer: 9.304 ± 0.042	6.814AlaThr: 6.814 ± 0.034	8.181AlaVal: 8.181 ± 0.039	1.456AlaTrp: 1.456 ± 0.018	2.167AlaTyr: 2.167 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.849CysAla: 1.849 ± 0.02	0.393CysCys: 0.393 ± 0.009	0.889CysAsp: 0.889 ± 0.013	0.951CysGlu: 0.951 ± 0.012	0.577CysPhe: 0.577 ± 0.009	1.292CysGly: 1.292 ± 0.015	0.352CysHis: 0.352 ± 0.007	0.631CysIle: 0.631 ± 0.01	0.603CysLys: 0.603 ± 0.011	1.377CysLeu: 1.377 ± 0.017	0.371CysMet: 0.371 ± 0.008	0.442CysAsn: 0.442 ± 0.007	0.724CysPro: 0.724 ± 0.013	0.416CysGln: 0.416 ± 0.008	0.945CysArg: 0.945 ± 0.013	1.149CysSer: 1.149 ± 0.016	0.964CysThr: 0.964 ± 0.015	1.207CysVal: 1.207 ± 0.014	0.242CysTrp: 0.242 ± 0.006	0.359CysTyr: 0.359 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.328AspAla: 7.328 ± 0.035	0.734AspCys: 0.734 ± 0.012	3.613AspAsp: 3.613 ± 0.032	4.87AspGlu: 4.87 ± 0.031	1.629AspPhe: 1.629 ± 0.015	5.355AspGly: 5.355 ± 0.042	0.921AspHis: 0.921 ± 0.013	1.504AspIle: 1.504 ± 0.017	2.045AspLys: 2.045 ± 0.021	4.543AspLeu: 4.543 ± 0.031	1.079AspMet: 1.079 ± 0.014	1.042AspAsn: 1.042 ± 0.013	2.698AspPro: 2.698 ± 0.021	1.358AspGln: 1.358 ± 0.015	2.631AspArg: 2.631 ± 0.023	2.726AspSer: 2.726 ± 0.022	2.186AspThr: 2.186 ± 0.019	3.911AspVal: 3.911 ± 0.025	0.699AspTrp: 0.699 ± 0.011	1.023AspTyr: 1.023 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	9.869GluAla: 9.869 ± 0.073	0.893GluCys: 0.893 ± 0.014	3.099GluAsp: 3.099 ± 0.026	5.071GluGlu: 5.071 ± 0.042	1.693GluPhe: 1.693 ± 0.018	4.558GluGly: 4.558 ± 0.032	1.637GluHis: 1.637 ± 0.016	2.198GluIle: 2.198 ± 0.018	2.881GluLys: 2.881 ± 0.033	7.779GluLeu: 7.779 ± 0.049	1.777GluMet: 1.777 ± 0.016	1.249GluAsn: 1.249 ± 0.015	3.029GluPro: 3.029 ± 0.021	2.829GluGln: 2.829 ± 0.026	5.419GluArg: 5.419 ± 0.046	3.287GluSer: 3.287 ± 0.022	2.834GluThr: 2.834 ± 0.022	4.254GluVal: 4.254 ± 0.031	0.926GluTrp: 0.926 ± 0.012	1.368GluTyr: 1.368 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.354PheAla: 3.354 ± 0.024	0.552PheCys: 0.552 ± 0.009	2.196PheAsp: 2.196 ± 0.022	2.196PheGlu: 2.196 ± 0.017	1.224PhePhe: 1.224 ± 0.015	2.878PheGly: 2.878 ± 0.027	0.667PheHis: 0.667 ± 0.009	1.083PheIle: 1.083 ± 0.015	1.22PheLys: 1.22 ± 0.018	2.58PheLeu: 2.58 ± 0.026	0.671PheMet: 0.671 ± 0.01	0.978PheAsn: 0.978 ± 0.013	1.216PhePro: 1.216 ± 0.015	0.889PheGln: 0.889 ± 0.011	1.622PheArg: 1.622 ± 0.016	2.139PheSer: 2.139 ± 0.02	1.644PheThr: 1.644 ± 0.018	2.481PheVal: 2.481 ± 0.021	0.448PheTrp: 0.448 ± 0.009	0.778PheTyr: 0.778 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	9.734GlyAla: 9.734 ± 0.056	1.34GlyCys: 1.34 ± 0.018	4.077GlyAsp: 4.077 ± 0.034	4.36GlyGlu: 4.36 ± 0.032	2.545GlyPhe: 2.545 ± 0.026	7.958GlyGly: 7.958 ± 0.067	1.614GlyHis: 1.614 ± 0.018	2.547GlyIle: 2.547 ± 0.023	3.238GlyLys: 3.238 ± 0.027	6.431GlyLeu: 6.431 ± 0.036	1.792GlyMet: 1.792 ± 0.025	1.936GlyAsn: 1.936 ± 0.024	3.056GlyPro: 3.056 ± 0.025	2.208GlyGln: 2.208 ± 0.022	4.567GlyArg: 4.567 ± 0.028	5.87GlySer: 5.87 ± 0.038	4.305GlyThr: 4.305 ± 0.029	5.262GlyVal: 5.262 ± 0.033	1.191GlyTrp: 1.191 ± 0.017	1.718GlyTyr: 1.718 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	3.096HisAla: 3.096 ± 0.028	0.389HisCys: 0.389 ± 0.007	1.152HisAsp: 1.152 ± 0.015	1.597HisGlu: 1.597 ± 0.016	0.774HisPhe: 0.774 ± 0.01	1.935HisGly: 1.935 ± 0.02	0.605HisHis: 0.605 ± 0.009	0.688HisIle: 0.688 ± 0.01	0.802HisLys: 0.802 ± 0.011	2.171HisLeu: 2.171 ± 0.021	0.513HisMet: 0.513 ± 0.009	0.528HisAsn: 0.528 ± 0.009	1.226HisPro: 1.226 ± 0.013	0.697HisGln: 0.697 ± 0.01	1.471HisArg: 1.471 ± 0.017	1.445HisSer: 1.445 ± 0.014	1.137HisThr: 1.137 ± 0.012	1.798HisVal: 1.798 ± 0.015	0.34HisTrp: 0.34 ± 0.006	0.541HisTyr: 0.541 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.317IleAla: 4.317 ± 0.033	0.552IleCys: 0.552 ± 0.009	2.326IleAsp: 2.326 ± 0.02	2.727IleGlu: 2.727 ± 0.02	1.317IlePhe: 1.317 ± 0.017	2.734IleGly: 2.734 ± 0.021	0.645IleHis: 0.645 ± 0.011	1.312IleIle: 1.312 ± 0.017	1.618IleLys: 1.618 ± 0.02	2.702IleLeu: 2.702 ± 0.024	0.736IleMet: 0.736 ± 0.012	1.062IleAsn: 1.062 ± 0.011	1.409IlePro: 1.409 ± 0.014	0.989IleGln: 0.989 ± 0.012	1.874IleArg: 1.874 ± 0.017	2.48IleSer: 2.48 ± 0.02	1.842IleThr: 1.842 ± 0.023	2.632IleVal: 2.632 ± 0.019	0.392IleTrp: 0.392 ± 0.007	0.713IleTyr: 0.713 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	5.431LysAla: 5.431 ± 0.052	0.508LysCys: 0.508 ± 0.009	1.979LysAsp: 1.979 ± 0.023	3.019LysGlu: 3.019 ± 0.03	1.007LysPhe: 1.007 ± 0.014	2.933LysGly: 2.933 ± 0.024	0.937LysHis: 0.937 ± 0.012	1.369LysIle: 1.369 ± 0.018	2.437LysLys: 2.437 ± 0.033	4.492LysLeu: 4.492 ± 0.039	1.089LysMet: 1.089 ± 0.013	0.963LysAsn: 0.963 ± 0.013	2.162LysPro: 2.162 ± 0.02	1.686LysGln: 1.686 ± 0.017	2.955LysArg: 2.955 ± 0.025	2.25LysSer: 2.25 ± 0.023	1.946LysThr: 1.946 ± 0.02	2.654LysVal: 2.654 ± 0.023	0.518LysTrp: 0.518 ± 0.009	0.916LysTyr: 0.916 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	11.965LeuAla: 11.965 ± 0.056	1.728LeuCys: 1.728 ± 0.016	5.368LeuAsp: 5.368 ± 0.034	6.734LeuGlu: 6.734 ± 0.039	3.025LeuPhe: 3.025 ± 0.024	7.19LeuGly: 7.19 ± 0.044	2.632LeuHis: 2.632 ± 0.021	3.39LeuIle: 3.39 ± 0.028	4.294LeuLys: 4.294 ± 0.035	10.791LeuLeu: 10.791 ± 0.06	2.143LeuMet: 2.143 ± 0.017	2.561LeuAsn: 2.561 ± 0.021	5.775LeuPro: 5.775 ± 0.032	4.087LeuGln: 4.087 ± 0.031	7.825LeuArg: 7.825 ± 0.047	7.12LeuSer: 7.12 ± 0.04	5.272LeuThr: 5.272 ± 0.035	6.575LeuVal: 6.575 ± 0.035	1.209LeuTrp: 1.209 ± 0.014	2.003LeuTyr: 2.003 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.777MetAla: 2.777 ± 0.024	0.354MetCys: 0.354 ± 0.007	1.054MetAsp: 1.054 ± 0.013	1.31MetGlu: 1.31 ± 0.014	0.576MetPhe: 0.576 ± 0.01	1.666MetGly: 1.666 ± 0.022	0.668MetHis: 0.668 ± 0.011	0.793MetIle: 0.793 ± 0.011	0.886MetLys: 0.886 ± 0.011	2.823MetLeu: 2.823 ± 0.024	0.68MetMet: 0.68 ± 0.012	0.575MetAsn: 0.575 ± 0.009	1.515MetPro: 1.515 ± 0.017	1.071MetGln: 1.071 ± 0.013	1.904MetArg: 1.904 ± 0.018	1.587MetSer: 1.587 ± 0.017	1.181MetThr: 1.181 ± 0.015	1.402MetVal: 1.402 ± 0.015	0.273MetTrp: 0.273 ± 0.006	0.471MetTyr: 0.471 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.02AsnAla: 3.02 ± 0.021	0.369AsnCys: 0.369 ± 0.008	1.233AsnAsp: 1.233 ± 0.015	1.596AsnGlu: 1.596 ± 0.016	0.829AsnPhe: 0.829 ± 0.012	2.231AsnGly: 2.231 ± 0.025	0.496AsnHis: 0.496 ± 0.008	0.878AsnIle: 0.878 ± 0.012	1.043AsnLys: 1.043 ± 0.015	2.411AsnLeu: 2.411 ± 0.02	0.581AsnMet: 0.581 ± 0.009	0.694AsnAsn: 0.694 ± 0.012	1.38AsnPro: 1.38 ± 0.013	0.806AsnGln: 0.806 ± 0.012	1.324AsnArg: 1.324 ± 0.015	1.421AsnSer: 1.421 ± 0.015	1.203AsnThr: 1.203 ± 0.013	1.803AsnVal: 1.803 ± 0.016	0.329AsnTrp: 0.329 ± 0.007	0.582AsnTyr: 0.582 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	6.401ProAla: 6.401 ± 0.042	0.686ProCys: 0.686 ± 0.013	2.621ProAsp: 2.621 ± 0.021	3.369ProGlu: 3.369 ± 0.023	1.611ProPhe: 1.611 ± 0.016	3.666ProGly: 3.666 ± 0.029	1.141ProHis: 1.141 ± 0.013	1.74ProIle: 1.74 ± 0.016	2.182ProLys: 2.182 ± 0.021	5.246ProLeu: 5.246 ± 0.034	1.251ProMet: 1.251 ± 0.015	1.406ProAsn: 1.406 ± 0.015	5.44ProPro: 5.44 ± 0.043	1.632ProGln: 1.632 ± 0.017	3.201ProArg: 3.201 ± 0.025	4.788ProSer: 4.788 ± 0.038	3.402ProThr: 3.402 ± 0.026	3.201ProVal: 3.201 ± 0.023	0.696ProTrp: 0.696 ± 0.011	1.025ProTyr: 1.025 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	4.358GlnAla: 4.358 ± 0.036	0.528GlnCys: 0.528 ± 0.009	1.181GlnAsp: 1.181 ± 0.014	1.911GlnGlu: 1.911 ± 0.018	0.921GlnPhe: 0.921 ± 0.012	2.078GlnGly: 2.078 ± 0.019	0.983GlnHis: 0.983 ± 0.013	1.232GlnIle: 1.232 ± 0.014	1.414GlnLys: 1.414 ± 0.018	4.68GlnLeu: 4.68 ± 0.032	0.999GlnMet: 0.999 ± 0.015	0.714GlnAsn: 0.714 ± 0.01	2.068GlnPro: 2.068 ± 0.019	2.124GlnGln: 2.124 ± 0.023	3.119GlnArg: 3.119 ± 0.031	2.003GlnSer: 2.003 ± 0.017	1.613GlnThr: 1.613 ± 0.015	2.081GlnVal: 2.081 ± 0.017	0.506GlnTrp: 0.506 ± 0.008	0.777GlnTyr: 0.777 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	8.607ArgAla: 8.607 ± 0.048	1.138ArgCys: 1.138 ± 0.014	3.22ArgAsp: 3.22 ± 0.024	4.713ArgGlu: 4.713 ± 0.043	2.037ArgPhe: 2.037 ± 0.02	4.425ArgGly: 4.425 ± 0.031	1.656ArgHis: 1.656 ± 0.019	2.264ArgIle: 2.264 ± 0.019	2.666ArgLys: 2.666 ± 0.023	7.232ArgLeu: 7.232 ± 0.047	1.623ArgMet: 1.623 ± 0.016	1.502ArgAsn: 1.502 ± 0.016	3.307ArgPro: 3.307 ± 0.029	2.661ArgGln: 2.661 ± 0.025	5.762ArgArg: 5.762 ± 0.045	4.476ArgSer: 4.476 ± 0.026	3.343ArgThr: 3.343 ± 0.024	4.508ArgVal: 4.508 ± 0.029	1.018ArgTrp: 1.018 ± 0.014	1.376ArgTyr: 1.376 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	8.896SerAla: 8.896 ± 0.043	1.047SerCys: 1.047 ± 0.015	3.277SerAsp: 3.277 ± 0.024	3.818SerGlu: 3.818 ± 0.024	2.295SerPhe: 2.295 ± 0.02	5.599SerGly: 5.599 ± 0.036	1.406SerHis: 1.406 ± 0.014	2.659SerIle: 2.659 ± 0.026	2.687SerLys: 2.687 ± 0.025	6.579SerLeu: 6.579 ± 0.037	1.752SerMet: 1.752 ± 0.018	1.646SerAsn: 1.646 ± 0.017	3.942SerPro: 3.942 ± 0.031	2.001SerGln: 2.001 ± 0.017	4.198SerArg: 4.198 ± 0.026	6.334SerSer: 6.334 ± 0.04	4.071SerThr: 4.071 ± 0.028	4.418SerVal: 4.418 ± 0.025	0.948SerTrp: 0.948 ± 0.013	1.346SerTyr: 1.346 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	6.605ThrAla: 6.605 ± 0.039	0.867ThrCys: 0.867 ± 0.015	2.443ThrAsp: 2.443 ± 0.02	2.79ThrGlu: 2.79 ± 0.019	1.906ThrPhe: 1.906 ± 0.021	3.728ThrGly: 3.728 ± 0.027	1.13ThrHis: 1.13 ± 0.013	2.153ThrIle: 2.153 ± 0.021	2.042ThrLys: 2.042 ± 0.021	5.639ThrLeu: 5.639 ± 0.034	1.214ThrMet: 1.214 ± 0.013	1.323ThrAsn: 1.323 ± 0.015	3.367ThrPro: 3.367 ± 0.028	1.56ThrGln: 1.56 ± 0.015	3.071ThrArg: 3.071 ± 0.021	4.021ThrSer: 4.021 ± 0.031	3.031ThrThr: 3.031 ± 0.024	3.473ThrVal: 3.473 ± 0.025	0.733ThrTrp: 0.733 ± 0.011	1.177ThrTyr: 1.177 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	8.256ValAla: 8.256 ± 0.038	1.143ValCys: 1.143 ± 0.014	3.785ValAsp: 3.785 ± 0.023	4.249ValGlu: 4.249 ± 0.026	1.96ValPhe: 1.96 ± 0.017	4.703ValGly: 4.703 ± 0.03	1.717ValHis: 1.717 ± 0.015	2.277ValIle: 2.277 ± 0.022	2.387ValLys: 2.387 ± 0.019	7.251ValLeu: 7.251 ± 0.042	1.449ValMet: 1.449 ± 0.014	1.681ValAsn: 1.681 ± 0.016	3.908ValPro: 3.908 ± 0.025	2.509ValGln: 2.509 ± 0.021	4.794ValArg: 4.794 ± 0.025	4.282ValSer: 4.282 ± 0.026	3.555ValThr: 3.555 ± 0.026	4.857ValVal: 4.857 ± 0.03	0.892ValTrp: 0.892 ± 0.013	1.407ValTyr: 1.407 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	1.363TrpAla: 1.363 ± 0.014	0.264TrpCys: 0.264 ± 0.006	0.726TrpAsp: 0.726 ± 0.01	0.738TrpGlu: 0.738 ± 0.011	0.395TrpPhe: 0.395 ± 0.009	0.798TrpGly: 0.798 ± 0.011	0.394TrpHis: 0.394 ± 0.009	0.431TrpIle: 0.431 ± 0.007	0.569TrpLys: 0.569 ± 0.011	1.515TrpLeu: 1.515 ± 0.016	0.366TrpMet: 0.366 ± 0.007	0.421TrpAsn: 0.421 ± 0.009	0.611TrpPro: 0.611 ± 0.01	0.573TrpGln: 0.573 ± 0.008	1.171TrpArg: 1.171 ± 0.014	0.913TrpSer: 0.913 ± 0.012	0.742TrpThr: 0.742 ± 0.01	0.803TrpVal: 0.803 ± 0.012	0.238TrpTrp: 0.238 ± 0.005	0.328TrpTyr: 0.328 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.267TyrAla: 2.267 ± 0.021	0.378TyrCys: 0.378 ± 0.008	1.319TyrAsp: 1.319 ± 0.016	1.424TyrGlu: 1.424 ± 0.014	0.794TyrPhe: 0.794 ± 0.013	1.712TyrGly: 1.712 ± 0.021	0.455TyrHis: 0.455 ± 0.008	0.715TyrIle: 0.715 ± 0.012	0.818TyrLys: 0.818 ± 0.011	1.944TyrLeu: 1.944 ± 0.018	0.495TyrMet: 0.495 ± 0.009	0.673TyrAsn: 0.673 ± 0.01	0.855TyrPro: 0.855 ± 0.013	0.623TyrGln: 0.623 ± 0.009	1.227TyrArg: 1.227 ± 0.012	1.323TyrSer: 1.323 ± 0.015	1.186TyrThr: 1.186 ± 0.016	1.561TyrVal: 1.561 ± 0.015	0.305TyrTrp: 0.305 ± 0.006	0.581TyrTyr: 0.581 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16679 proteins (7768616 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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