Amino acid dipepetide frequency for Peltaster fructicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.16AlaAla: 10.16 ± 0.074	1.039AlaCys: 1.039 ± 0.018	4.861AlaAsp: 4.861 ± 0.038	5.576AlaGlu: 5.576 ± 0.05	3.248AlaPhe: 3.248 ± 0.031	6.126AlaGly: 6.126 ± 0.05	1.974AlaHis: 1.974 ± 0.025	4.525AlaIle: 4.525 ± 0.037	4.407AlaLys: 4.407 ± 0.04	8.358AlaLeu: 8.358 ± 0.056	2.095AlaMet: 2.095 ± 0.022	3.001AlaAsn: 3.001 ± 0.027	4.8AlaPro: 4.8 ± 0.049	4.24AlaGln: 4.24 ± 0.04	5.454AlaArg: 5.454 ± 0.041	7.714AlaSer: 7.714 ± 0.061	5.837AlaThr: 5.837 ± 0.043	5.847AlaVal: 5.847 ± 0.045	1.207AlaTrp: 1.207 ± 0.018	2.391AlaTyr: 2.391 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.907CysAla: 0.907 ± 0.016	0.222CysCys: 0.222 ± 0.009	0.613CysAsp: 0.613 ± 0.013	0.557CysGlu: 0.557 ± 0.014	0.485CysPhe: 0.485 ± 0.012	0.825CysGly: 0.825 ± 0.016	0.291CysHis: 0.291 ± 0.009	0.673CysIle: 0.673 ± 0.013	0.489CysLys: 0.489 ± 0.011	1.119CysLeu: 1.119 ± 0.02	0.257CysMet: 0.257 ± 0.007	0.413CysAsn: 0.413 ± 0.011	0.568CysPro: 0.568 ± 0.013	0.452CysGln: 0.452 ± 0.012	0.657CysArg: 0.657 ± 0.013	0.811CysSer: 0.811 ± 0.016	0.677CysThr: 0.677 ± 0.013	0.723CysVal: 0.723 ± 0.013	0.186CysTrp: 0.186 ± 0.007	0.348CysTyr: 0.348 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	5.379AspAla: 5.379 ± 0.039	0.614AspCys: 0.614 ± 0.013	4.807AspAsp: 4.807 ± 0.061	4.721AspGlu: 4.721 ± 0.057	2.237AspPhe: 2.237 ± 0.026	4.018AspGly: 4.018 ± 0.036	1.353AspHis: 1.353 ± 0.021	3.127AspIle: 3.127 ± 0.028	2.556AspLys: 2.556 ± 0.029	5.192AspLeu: 5.192 ± 0.036	1.329AspMet: 1.329 ± 0.019	2.072AspAsn: 2.072 ± 0.023	2.985AspPro: 2.985 ± 0.03	2.057AspGln: 2.057 ± 0.025	3.24AspArg: 3.24 ± 0.039	4.128AspSer: 4.128 ± 0.038	3.387AspThr: 3.387 ± 0.03	3.926AspVal: 3.926 ± 0.034	0.9AspTrp: 0.9 ± 0.014	1.658AspTyr: 1.658 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	5.512GluAla: 5.512 ± 0.049	0.565GluCys: 0.565 ± 0.013	4.328GluAsp: 4.328 ± 0.044	4.881GluGlu: 4.881 ± 0.06	1.666GluPhe: 1.666 ± 0.023	3.245GluGly: 3.245 ± 0.034	1.713GluHis: 1.713 ± 0.023	2.831GluIle: 2.831 ± 0.03	3.377GluLys: 3.377 ± 0.035	5.624GluLeu: 5.624 ± 0.056	1.328GluMet: 1.328 ± 0.019	1.872GluAsn: 1.872 ± 0.023	2.676GluPro: 2.676 ± 0.033	3.061GluGln: 3.061 ± 0.032	4.004GluArg: 4.004 ± 0.038	3.988GluSer: 3.988 ± 0.034	3.338GluThr: 3.338 ± 0.033	3.559GluVal: 3.559 ± 0.029	0.781GluTrp: 0.781 ± 0.014	1.598GluTyr: 1.598 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.166PheAla: 3.166 ± 0.037	0.494PheCys: 0.494 ± 0.012	2.356PheAsp: 2.356 ± 0.025	2.104PheGlu: 2.104 ± 0.025	1.407PhePhe: 1.407 ± 0.023	2.707PheGly: 2.707 ± 0.034	0.792PheHis: 0.792 ± 0.014	1.618PheIle: 1.618 ± 0.021	1.469PheLys: 1.469 ± 0.022	3.023PheLeu: 3.023 ± 0.034	0.735PheMet: 0.735 ± 0.014	1.391PheAsn: 1.391 ± 0.021	1.592PhePro: 1.592 ± 0.024	1.242PheGln: 1.242 ± 0.016	1.763PheArg: 1.763 ± 0.023	2.689PheSer: 2.689 ± 0.025	2.151PheThr: 2.151 ± 0.025	2.335PheVal: 2.335 ± 0.027	0.561PheTrp: 0.561 ± 0.014	1.003PheTyr: 1.003 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.224GlyAla: 5.224 ± 0.048	0.759GlyCys: 0.759 ± 0.016	3.46GlyAsp: 3.46 ± 0.028	3.289GlyGlu: 3.289 ± 0.028	2.613GlyPhe: 2.613 ± 0.033	4.976GlyGly: 4.976 ± 0.052	1.676GlyHis: 1.676 ± 0.023	3.365GlyIle: 3.365 ± 0.032	3.309GlyLys: 3.309 ± 0.036	5.796GlyLeu: 5.796 ± 0.048	1.559GlyMet: 1.559 ± 0.023	2.327GlyAsn: 2.327 ± 0.028	2.901GlyPro: 2.901 ± 0.03	2.711GlyGln: 2.711 ± 0.033	3.963GlyArg: 3.963 ± 0.036	5.419GlySer: 5.419 ± 0.045	4.001GlyThr: 4.001 ± 0.041	4.086GlyVal: 4.086 ± 0.04	1.077GlyTrp: 1.077 ± 0.019	2.079GlyTyr: 2.079 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.152HisAla: 2.152 ± 0.026	0.308HisCys: 0.308 ± 0.008	1.578HisAsp: 1.578 ± 0.021	1.482HisGlu: 1.482 ± 0.021	0.914HisPhe: 0.914 ± 0.016	1.733HisGly: 1.733 ± 0.024	0.813HisHis: 0.813 ± 0.018	1.29HisIle: 1.29 ± 0.017	1.099HisLys: 1.099 ± 0.018	2.152HisLeu: 2.152 ± 0.022	0.507HisMet: 0.507 ± 0.012	0.945HisAsn: 0.945 ± 0.016	1.417HisPro: 1.417 ± 0.022	0.992HisGln: 0.992 ± 0.017	1.494HisArg: 1.494 ± 0.02	1.872HisSer: 1.872 ± 0.025	1.439HisThr: 1.439 ± 0.024	1.468HisVal: 1.468 ± 0.022	0.352HisTrp: 0.352 ± 0.008	0.684HisTyr: 0.684 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.614IleAla: 4.614 ± 0.034	0.679IleCys: 0.679 ± 0.014	3.176IleAsp: 3.176 ± 0.029	3.019IleGlu: 3.019 ± 0.031	1.816IlePhe: 1.816 ± 0.027	3.112IleGly: 3.112 ± 0.032	1.125IleHis: 1.125 ± 0.017	2.397IleIle: 2.397 ± 0.027	2.205IleLys: 2.205 ± 0.024	4.232IleLeu: 4.232 ± 0.041	1.007IleMet: 1.007 ± 0.02	1.822IleAsn: 1.822 ± 0.021	2.71IlePro: 2.71 ± 0.026	1.776IleGln: 1.776 ± 0.023	2.734IleArg: 2.734 ± 0.027	3.731IleSer: 3.731 ± 0.037	3.117IleThr: 3.117 ± 0.034	3.306IleVal: 3.306 ± 0.03	0.688IleTrp: 0.688 ± 0.015	1.331IleTyr: 1.331 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.552LysAla: 4.552 ± 0.043	0.442LysCys: 0.442 ± 0.012	3.055LysAsp: 3.055 ± 0.03	3.152LysGlu: 3.152 ± 0.036	1.259LysPhe: 1.259 ± 0.019	2.639LysGly: 2.639 ± 0.031	1.34LysHis: 1.34 ± 0.019	2.23LysIle: 2.23 ± 0.026	3.178LysLys: 3.178 ± 0.048	4.215LysLeu: 4.215 ± 0.034	0.972LysMet: 0.972 ± 0.016	1.602LysAsn: 1.602 ± 0.022	2.599LysPro: 2.599 ± 0.03	2.275LysGln: 2.275 ± 0.028	3.553LysArg: 3.553 ± 0.037	3.535LysSer: 3.535 ± 0.038	3.011LysThr: 3.011 ± 0.032	2.791LysVal: 2.791 ± 0.03	0.61LysTrp: 0.61 ± 0.012	1.286LysTyr: 1.286 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	8.373LeuAla: 8.373 ± 0.057	1.153LeuCys: 1.153 ± 0.021	5.444LeuAsp: 5.444 ± 0.043	5.406LeuGlu: 5.406 ± 0.054	3.021LeuPhe: 3.021 ± 0.034	5.523LeuGly: 5.523 ± 0.04	2.276LeuHis: 2.276 ± 0.026	3.854LeuIle: 3.854 ± 0.039	4.235LeuLys: 4.235 ± 0.04	8.363LeuLeu: 8.363 ± 0.078	1.746LeuMet: 1.746 ± 0.021	3.106LeuAsn: 3.106 ± 0.03	5.43LeuPro: 5.43 ± 0.041	4.287LeuGln: 4.287 ± 0.038	5.724LeuArg: 5.724 ± 0.042	7.151LeuSer: 7.151 ± 0.047	5.139LeuThr: 5.139 ± 0.046	5.214LeuVal: 5.214 ± 0.042	1.116LeuTrp: 1.116 ± 0.021	2.323LeuTyr: 2.323 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.206MetAla: 2.206 ± 0.023	0.219MetCys: 0.219 ± 0.007	1.241MetAsp: 1.241 ± 0.017	1.104MetGlu: 1.104 ± 0.019	0.695MetPhe: 0.695 ± 0.014	1.201MetGly: 1.201 ± 0.019	0.542MetHis: 0.542 ± 0.012	1.004MetIle: 1.004 ± 0.017	0.956MetLys: 0.956 ± 0.018	2.076MetLeu: 2.076 ± 0.025	0.535MetMet: 0.535 ± 0.013	0.784MetAsn: 0.784 ± 0.014	1.355MetPro: 1.355 ± 0.019	1.042MetGln: 1.042 ± 0.016	1.266MetArg: 1.266 ± 0.018	1.999MetSer: 1.999 ± 0.024	1.32MetThr: 1.32 ± 0.019	1.186MetVal: 1.186 ± 0.016	0.238MetTrp: 0.238 ± 0.007	0.54MetTyr: 0.54 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.487AsnAla: 3.487 ± 0.03	0.374AsnCys: 0.374 ± 0.011	2.198AsnAsp: 2.198 ± 0.023	2.006AsnGlu: 2.006 ± 0.023	1.243AsnPhe: 1.243 ± 0.015	2.953AsnGly: 2.953 ± 0.035	0.79AsnHis: 0.79 ± 0.016	1.975AsnIle: 1.975 ± 0.023	1.57AsnLys: 1.57 ± 0.02	2.967AsnLeu: 2.967 ± 0.032	0.764AsnMet: 0.764 ± 0.012	1.483AsnAsn: 1.483 ± 0.025	1.996AsnPro: 1.996 ± 0.027	1.205AsnGln: 1.205 ± 0.018	1.789AsnArg: 1.789 ± 0.022	2.483AsnSer: 2.483 ± 0.029	2.344AsnThr: 2.344 ± 0.026	2.369AsnVal: 2.369 ± 0.023	0.478AsnTrp: 0.478 ± 0.011	0.978AsnTyr: 0.978 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	5.499ProAla: 5.499 ± 0.049	0.409ProCys: 0.409 ± 0.011	3.043ProAsp: 3.043 ± 0.032	3.357ProGlu: 3.357 ± 0.034	1.85ProPhe: 1.85 ± 0.023	3.593ProGly: 3.593 ± 0.033	1.246ProHis: 1.246 ± 0.02	2.383ProIle: 2.383 ± 0.025	2.424ProLys: 2.424 ± 0.029	4.407ProLeu: 4.407 ± 0.038	1.063ProMet: 1.063 ± 0.017	1.852ProAsn: 1.852 ± 0.024	4.316ProPro: 4.316 ± 0.072	2.616ProGln: 2.616 ± 0.032	3.155ProArg: 3.155 ± 0.031	5.296ProSer: 5.296 ± 0.051	3.834ProThr: 3.834 ± 0.042	3.587ProVal: 3.587 ± 0.042	0.661ProTrp: 0.661 ± 0.013	1.516ProTyr: 1.516 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	4.252GlnAla: 4.252 ± 0.041	0.459GlnCys: 0.459 ± 0.012	2.46GlnAsp: 2.46 ± 0.029	2.596GlnGlu: 2.596 ± 0.027	1.227GlnPhe: 1.227 ± 0.018	2.568GlnGly: 2.568 ± 0.031	1.418GlnHis: 1.418 ± 0.022	1.974GlnIle: 1.974 ± 0.022	2.017GlnLys: 2.017 ± 0.026	3.881GlnLeu: 3.881 ± 0.038	0.914GlnMet: 0.914 ± 0.017	1.527GlnAsn: 1.527 ± 0.023	2.708GlnPro: 2.708 ± 0.032	3.077GlnGln: 3.077 ± 0.054	3.08GlnArg: 3.08 ± 0.033	3.595GlnSer: 3.595 ± 0.036	2.67GlnThr: 2.67 ± 0.027	2.254GlnVal: 2.254 ± 0.028	0.63GlnTrp: 0.63 ± 0.014	1.361GlnTyr: 1.361 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	5.189ArgAla: 5.189 ± 0.039	0.69ArgCys: 0.69 ± 0.014	3.348ArgAsp: 3.348 ± 0.034	3.606ArgGlu: 3.606 ± 0.034	1.987ArgPhe: 1.987 ± 0.022	3.496ArgGly: 3.496 ± 0.034	1.606ArgHis: 1.606 ± 0.023	2.777ArgIle: 2.777 ± 0.027	3.492ArgLys: 3.492 ± 0.032	5.551ArgLeu: 5.551 ± 0.041	1.368ArgMet: 1.368 ± 0.02	2.128ArgAsn: 2.128 ± 0.023	3.504ArgPro: 3.504 ± 0.036	3.027ArgGln: 3.027 ± 0.034	5.156ArgArg: 5.156 ± 0.058	5.014ArgSer: 5.014 ± 0.052	3.532ArgThr: 3.532 ± 0.033	3.229ArgVal: 3.229 ± 0.031	0.902ArgTrp: 0.902 ± 0.017	1.658ArgTyr: 1.658 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.165SerAla: 7.165 ± 0.061	0.775SerCys: 0.775 ± 0.015	4.229SerAsp: 4.229 ± 0.038	3.934SerGlu: 3.934 ± 0.031	2.852SerPhe: 2.852 ± 0.028	5.279SerGly: 5.279 ± 0.053	1.833SerHis: 1.833 ± 0.023	4.135SerIle: 4.135 ± 0.035	3.904SerLys: 3.904 ± 0.041	6.878SerLeu: 6.878 ± 0.053	1.852SerMet: 1.852 ± 0.023	2.965SerAsn: 2.965 ± 0.031	4.891SerPro: 4.891 ± 0.055	3.462SerGln: 3.462 ± 0.034	4.946SerArg: 4.946 ± 0.045	8.552SerSer: 8.552 ± 0.11	6.294SerThr: 6.294 ± 0.068	4.563SerVal: 4.563 ± 0.041	1.058SerTrp: 1.058 ± 0.017	2.06SerTyr: 2.06 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.134ThrAla: 6.134 ± 0.046	0.707ThrCys: 0.707 ± 0.015	3.083ThrAsp: 3.083 ± 0.03	3.091ThrGlu: 3.091 ± 0.032	2.248ThrPhe: 2.248 ± 0.025	4.184ThrGly: 4.184 ± 0.04	1.369ThrHis: 1.369 ± 0.017	3.43ThrIle: 3.43 ± 0.04	2.763ThrLys: 2.763 ± 0.03	5.44ThrLeu: 5.44 ± 0.042	1.263ThrMet: 1.263 ± 0.018	2.214ThrAsn: 2.214 ± 0.023	4.247ThrPro: 4.247 ± 0.044	2.571ThrGln: 2.571 ± 0.025	3.319ThrArg: 3.319 ± 0.032	5.905ThrSer: 5.905 ± 0.067	5.249ThrThr: 5.249 ± 0.065	3.909ThrVal: 3.909 ± 0.045	0.816ThrTrp: 0.816 ± 0.016	1.727ThrTyr: 1.727 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	5.471ValAla: 5.471 ± 0.039	0.767ValCys: 0.767 ± 0.015	3.797ValAsp: 3.797 ± 0.03	3.813ValGlu: 3.813 ± 0.034	2.214ValPhe: 2.214 ± 0.026	3.648ValGly: 3.648 ± 0.038	1.428ValHis: 1.428 ± 0.019	2.899ValIle: 2.899 ± 0.028	3.031ValLys: 3.031 ± 0.033	5.737ValLeu: 5.737 ± 0.041	1.279ValMet: 1.279 ± 0.019	2.194ValAsn: 2.194 ± 0.024	3.49ValPro: 3.49 ± 0.034	2.71ValGln: 2.71 ± 0.031	3.464ValArg: 3.464 ± 0.034	4.647ValSer: 4.647 ± 0.042	3.605ValThr: 3.605 ± 0.038	4.259ValVal: 4.259 ± 0.043	0.803ValTrp: 0.803 ± 0.014	1.716ValTyr: 1.716 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.038TrpAla: 1.038 ± 0.017	0.191TrpCys: 0.191 ± 0.007	0.807TrpAsp: 0.807 ± 0.016	0.702TrpGlu: 0.702 ± 0.015	0.511TrpPhe: 0.511 ± 0.011	0.698TrpGly: 0.698 ± 0.015	0.384TrpHis: 0.384 ± 0.009	0.742TrpIle: 0.742 ± 0.016	0.682TrpLys: 0.682 ± 0.013	1.364TrpLeu: 1.364 ± 0.021	0.32TrpMet: 0.32 ± 0.008	0.568TrpAsn: 0.568 ± 0.013	0.586TrpPro: 0.586 ± 0.013	0.718TrpGln: 0.718 ± 0.015	0.944TrpArg: 0.944 ± 0.016	1.115TrpSer: 1.115 ± 0.017	0.968TrpThr: 0.968 ± 0.014	0.723TrpVal: 0.723 ± 0.015	0.245TrpTrp: 0.245 ± 0.009	0.411TrpTyr: 0.411 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.38TyrAla: 2.38 ± 0.024	0.408TyrCys: 0.408 ± 0.011	1.803TyrAsp: 1.803 ± 0.023	1.55TyrGlu: 1.55 ± 0.02	1.108TyrPhe: 1.108 ± 0.018	2.064TyrGly: 2.064 ± 0.026	0.72TyrHis: 0.72 ± 0.014	1.369TyrIle: 1.369 ± 0.019	1.134TyrLys: 1.134 ± 0.019	2.511TyrLeu: 2.511 ± 0.028	0.614TyrMet: 0.614 ± 0.014	1.184TyrAsn: 1.184 ± 0.018	1.338TyrPro: 1.338 ± 0.021	1.146TyrGln: 1.146 ± 0.019	1.555TyrArg: 1.555 ± 0.022	1.983TyrSer: 1.983 ± 0.027	1.756TyrThr: 1.756 ± 0.024	1.637TyrVal: 1.637 ± 0.024	0.408TyrTrp: 0.408 ± 0.011	0.924TyrTyr: 0.924 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8072 proteins (4031696 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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