Amino acid dipepetide frequency for Lynx pardinus (Iberian lynx) (Felis pardina)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.698AlaAla: 6.698 ± 0.037	1.388AlaCys: 1.388 ± 0.011	2.943AlaAsp: 2.943 ± 0.013	4.74AlaGlu: 4.74 ± 0.022	2.6AlaPhe: 2.6 ± 0.015	4.859AlaGly: 4.859 ± 0.029	1.559AlaHis: 1.559 ± 0.011	2.711AlaIle: 2.711 ± 0.015	3.453AlaLys: 3.453 ± 0.02	7.099AlaLeu: 7.099 ± 0.028	1.446AlaMet: 1.446 ± 0.01	2.005AlaAsn: 2.005 ± 0.011	4.381AlaPro: 4.381 ± 0.026	3.241AlaGln: 3.241 ± 0.018	3.789AlaArg: 3.789 ± 0.019	5.869AlaSer: 5.869 ± 0.026	3.579AlaThr: 3.579 ± 0.021	4.699AlaVal: 4.699 ± 0.02	0.786AlaTrp: 0.786 ± 0.008	1.483AlaTyr: 1.483 ± 0.012	0.01AlaXaa: 0.01 ± 0.001
Cys	1.264CysAla: 1.264 ± 0.012	0.586CysCys: 0.586 ± 0.011	0.987CysAsp: 0.987 ± 0.011	1.257CysGlu: 1.257 ± 0.016	0.819CysPhe: 0.819 ± 0.009	1.776CysGly: 1.776 ± 0.021	0.663CysHis: 0.663 ± 0.008	0.895CysIle: 0.895 ± 0.008	1.115CysLys: 1.115 ± 0.011	2.098CysLeu: 2.098 ± 0.015	0.393CysMet: 0.393 ± 0.005	0.77CysAsn: 0.77 ± 0.009	1.373CysPro: 1.373 ± 0.015	1.026CysGln: 1.026 ± 0.012	1.285CysArg: 1.285 ± 0.011	1.961CysSer: 1.961 ± 0.016	1.047CysThr: 1.047 ± 0.01	1.296CysVal: 1.296 ± 0.011	0.283CysTrp: 0.283 ± 0.005	0.555CysTyr: 0.555 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	2.862AspAla: 2.862 ± 0.015	1.008AspCys: 1.008 ± 0.008	2.615AspAsp: 2.615 ± 0.019	3.378AspGlu: 3.378 ± 0.017	2.068AspPhe: 2.068 ± 0.014	3.258AspGly: 3.258 ± 0.022	1.131AspHis: 1.131 ± 0.008	2.528AspIle: 2.528 ± 0.016	2.517AspLys: 2.517 ± 0.016	4.982AspLeu: 4.982 ± 0.021	1.092AspMet: 1.092 ± 0.009	1.624AspAsn: 1.624 ± 0.012	2.943AspPro: 2.943 ± 0.016	1.823AspGln: 1.823 ± 0.012	2.469AspArg: 2.469 ± 0.014	4.19AspSer: 4.19 ± 0.021	2.458AspThr: 2.458 ± 0.014	3.079AspVal: 3.079 ± 0.022	0.6AspTrp: 0.6 ± 0.007	1.397AspTyr: 1.397 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	5.253GluAla: 5.253 ± 0.029	1.445GluCys: 1.445 ± 0.022	4.404GluAsp: 4.404 ± 0.02	8.071GluGlu: 8.071 ± 0.046	1.999GluPhe: 1.999 ± 0.012	4.308GluGly: 4.308 ± 0.024	1.495GluHis: 1.495 ± 0.009	3.109GluIle: 3.109 ± 0.018	5.525GluLys: 5.525 ± 0.03	6.389GluLeu: 6.389 ± 0.032	1.625GluMet: 1.625 ± 0.011	3.117GluAsn: 3.117 ± 0.017	3.347GluPro: 3.347 ± 0.019	3.166GluGln: 3.166 ± 0.021	4.101GluArg: 4.101 ± 0.023	4.468GluSer: 4.468 ± 0.019	3.456GluThr: 3.456 ± 0.02	4.175GluVal: 4.175 ± 0.022	0.679GluTrp: 0.679 ± 0.006	1.508GluTyr: 1.508 ± 0.012	0.002GluXaa: 0.002 ± 0.0
Phe	1.927PheAla: 1.927 ± 0.011	0.936PheCys: 0.936 ± 0.008	1.611PheAsp: 1.611 ± 0.01	1.956PheGlu: 1.956 ± 0.012	1.566PhePhe: 1.566 ± 0.013	2.175PheGly: 2.175 ± 0.016	1.021PheHis: 1.021 ± 0.009	1.762PheIle: 1.762 ± 0.015	1.726PheLys: 1.726 ± 0.013	4.008PheLeu: 4.008 ± 0.024	0.753PheMet: 0.753 ± 0.007	1.283PheAsn: 1.283 ± 0.01	2.019PhePro: 2.019 ± 0.013	1.748PheGln: 1.748 ± 0.01	1.938PheArg: 1.938 ± 0.013	3.412PheSer: 3.412 ± 0.018	1.973PheThr: 1.973 ± 0.014	2.073PheVal: 2.073 ± 0.014	0.47PheTrp: 0.47 ± 0.006	1.137PheTyr: 1.137 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	4.61GlyAla: 4.61 ± 0.024	1.257GlyCys: 1.257 ± 0.012	3.123GlyAsp: 3.123 ± 0.019	4.223GlyGlu: 4.223 ± 0.026	2.36GlyPhe: 2.36 ± 0.017	5.118GlyGly: 5.118 ± 0.039	1.745GlyHis: 1.745 ± 0.014	2.685GlyIle: 2.685 ± 0.017	3.811GlyLys: 3.811 ± 0.023	5.878GlyLeu: 5.878 ± 0.027	1.269GlyMet: 1.269 ± 0.01	2.347GlyAsn: 2.347 ± 0.014	4.47GlyPro: 4.47 ± 0.047	2.843GlyGln: 2.843 ± 0.017	3.905GlyArg: 3.905 ± 0.022	5.827GlySer: 5.827 ± 0.024	3.625GlyThr: 3.625 ± 0.02	3.532GlyVal: 3.532 ± 0.022	0.76GlyTrp: 0.76 ± 0.008	1.645GlyTyr: 1.645 ± 0.014	0.008GlyXaa: 0.008 ± 0.001
His	1.343HisAla: 1.343 ± 0.01	0.69HisCys: 0.69 ± 0.007	0.875HisAsp: 0.875 ± 0.007	1.328HisGlu: 1.328 ± 0.009	1.091HisPhe: 1.091 ± 0.01	1.57HisGly: 1.57 ± 0.012	0.879HisHis: 0.879 ± 0.012	1.229HisIle: 1.229 ± 0.01	1.256HisLys: 1.256 ± 0.009	2.955HisLeu: 2.955 ± 0.016	0.585HisMet: 0.585 ± 0.006	0.839HisAsn: 0.839 ± 0.008	1.682HisPro: 1.682 ± 0.011	1.394HisGln: 1.394 ± 0.015	1.626HisArg: 1.626 ± 0.012	2.276HisSer: 2.276 ± 0.014	1.602HisThr: 1.602 ± 0.017	1.526HisVal: 1.526 ± 0.011	0.352HisTrp: 0.352 ± 0.005	0.789HisTyr: 0.789 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.476IleAla: 2.476 ± 0.015	1.054IleCys: 1.054 ± 0.01	1.925IleAsp: 1.925 ± 0.013	2.527IleGlu: 2.527 ± 0.016	1.797IlePhe: 1.797 ± 0.013	2.1IleGly: 2.1 ± 0.013	1.356IleHis: 1.356 ± 0.013	2.319IleIle: 2.319 ± 0.02	2.57IleLys: 2.57 ± 0.017	4.476IleLeu: 4.476 ± 0.024	0.989IleMet: 0.989 ± 0.009	1.747IleAsn: 1.747 ± 0.012	2.57IlePro: 2.57 ± 0.014	2.26IleGln: 2.26 ± 0.014	2.344IleArg: 2.344 ± 0.014	3.629IleSer: 3.629 ± 0.018	2.513IleThr: 2.513 ± 0.021	2.408IleVal: 2.408 ± 0.015	0.496IleTrp: 0.496 ± 0.006	1.333IleTyr: 1.333 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	4.083LysAla: 4.083 ± 0.022	1.094LysCys: 1.094 ± 0.011	3.162LysAsp: 3.162 ± 0.02	5.206LysGlu: 5.206 ± 0.033	1.668LysPhe: 1.668 ± 0.013	3.254LysGly: 3.254 ± 0.025	1.404LysHis: 1.404 ± 0.011	2.703LysIle: 2.703 ± 0.015	4.741LysLys: 4.741 ± 0.031	5.131LysLeu: 5.131 ± 0.025	1.439LysMet: 1.439 ± 0.012	2.369LysAsn: 2.369 ± 0.015	3.184LysPro: 3.184 ± 0.022	2.625LysGln: 2.625 ± 0.016	3.301LysArg: 3.301 ± 0.016	4.01LysSer: 4.01 ± 0.022	3.148LysThr: 3.148 ± 0.015	3.446LysVal: 3.446 ± 0.021	0.584LysTrp: 0.584 ± 0.007	1.51LysTyr: 1.51 ± 0.013	0.001LysXaa: 0.001 ± 0.0
Leu	6.762LeuAla: 6.762 ± 0.031	2.152LeuCys: 2.152 ± 0.017	4.668LeuAsp: 4.668 ± 0.019	7.183LeuGlu: 7.183 ± 0.036	3.284LeuPhe: 3.284 ± 0.02	5.844LeuGly: 5.844 ± 0.023	2.739LeuHis: 2.739 ± 0.015	3.77LeuIle: 3.77 ± 0.021	5.747LeuLys: 5.747 ± 0.027	10.565LeuLeu: 10.565 ± 0.048	1.99LeuMet: 1.99 ± 0.013	3.447LeuAsn: 3.447 ± 0.018	6.084LeuPro: 6.084 ± 0.028	5.74LeuGln: 5.74 ± 0.025	5.986LeuArg: 5.986 ± 0.027	8.053LeuSer: 8.053 ± 0.033	5.068LeuThr: 5.068 ± 0.022	5.435LeuVal: 5.435 ± 0.023	1.112LeuTrp: 1.112 ± 0.01	2.453LeuTyr: 2.453 ± 0.016	0.004LeuXaa: 0.004 ± 0.0
Met	1.86MetAla: 1.86 ± 0.011	0.388MetCys: 0.388 ± 0.006	1.219MetAsp: 1.219 ± 0.009	1.841MetGlu: 1.841 ± 0.011	0.714MetPhe: 0.714 ± 0.007	1.259MetGly: 1.259 ± 0.01	0.458MetHis: 0.458 ± 0.006	0.812MetIle: 0.812 ± 0.007	1.426MetLys: 1.426 ± 0.009	1.941MetLeu: 1.941 ± 0.011	0.576MetMet: 0.576 ± 0.01	0.884MetAsn: 0.884 ± 0.009	1.074MetPro: 1.074 ± 0.014	0.918MetGln: 0.918 ± 0.008	1.038MetArg: 1.038 ± 0.008	1.546MetSer: 1.546 ± 0.009	1.104MetThr: 1.104 ± 0.009	1.377MetVal: 1.377 ± 0.011	0.23MetTrp: 0.23 ± 0.004	0.586MetTyr: 0.586 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.022AsnAla: 2.022 ± 0.012	0.78AsnCys: 0.78 ± 0.009	1.468AsnAsp: 1.468 ± 0.01	2.187AsnGlu: 2.187 ± 0.013	1.427AsnPhe: 1.427 ± 0.012	2.338AsnGly: 2.338 ± 0.018	0.934AsnHis: 0.934 ± 0.008	2.035AsnIle: 2.035 ± 0.014	2.208AsnLys: 2.208 ± 0.014	3.631AsnLeu: 3.631 ± 0.017	0.88AsnMet: 0.88 ± 0.007	1.461AsnAsn: 1.461 ± 0.011	2.18AsnPro: 2.18 ± 0.013	1.661AsnGln: 1.661 ± 0.013	1.8AsnArg: 1.8 ± 0.012	3.099AsnSer: 3.099 ± 0.016	1.95AsnThr: 1.95 ± 0.014	2.158AsnVal: 2.158 ± 0.014	0.429AsnTrp: 0.429 ± 0.005	1.058AsnTyr: 1.058 ± 0.01	0.001AsnXaa: 0.001 ± 0.0
Pro	5.105ProAla: 5.105 ± 0.029	1.136ProCys: 1.136 ± 0.013	2.793ProAsp: 2.793 ± 0.018	4.556ProGlu: 4.556 ± 0.023	1.933ProPhe: 1.933 ± 0.011	5.541ProGly: 5.541 ± 0.06	1.506ProHis: 1.506 ± 0.011	1.844ProIle: 1.844 ± 0.012	2.851ProLys: 2.851 ± 0.025	5.388ProLeu: 5.388 ± 0.023	1.095ProMet: 1.095 ± 0.009	1.796ProAsn: 1.796 ± 0.013	6.465ProPro: 6.465 ± 0.06	2.92ProGln: 2.92 ± 0.018	3.546ProArg: 3.546 ± 0.021	5.893ProSer: 5.893 ± 0.03	3.155ProThr: 3.155 ± 0.016	3.95ProVal: 3.95 ± 0.021	0.675ProTrp: 0.675 ± 0.008	1.511ProTyr: 1.511 ± 0.015	0.009ProXaa: 0.009 ± 0.001
Gln	3.516GlnAla: 3.516 ± 0.019	0.915GlnCys: 0.915 ± 0.01	2.335GlnAsp: 2.335 ± 0.012	3.947GlnGlu: 3.947 ± 0.023	1.325GlnPhe: 1.325 ± 0.009	2.864GlnGly: 2.864 ± 0.017	1.329GlnHis: 1.329 ± 0.01	1.993GlnIle: 1.993 ± 0.013	2.993GlnLys: 2.993 ± 0.019	4.726GlnLeu: 4.726 ± 0.024	1.123GlnMet: 1.123 ± 0.01	1.831GlnAsn: 1.831 ± 0.013	2.878GlnPro: 2.878 ± 0.02	3.077GlnGln: 3.077 ± 0.034	3.045GlnArg: 3.045 ± 0.02	3.218GlnSer: 3.218 ± 0.017	2.325GlnThr: 2.325 ± 0.014	2.77GlnVal: 2.77 ± 0.015	0.529GlnTrp: 0.529 ± 0.006	1.099GlnTyr: 1.099 ± 0.009	0.001GlnXaa: 0.001 ± 0.0
Arg	3.987ArgAla: 3.987 ± 0.021	1.197ArgCys: 1.197 ± 0.013	2.745ArgAsp: 2.745 ± 0.015	4.1ArgGlu: 4.1 ± 0.024	1.801ArgPhe: 1.801 ± 0.012	3.779ArgGly: 3.779 ± 0.025	1.574ArgHis: 1.574 ± 0.011	2.386ArgIle: 2.386 ± 0.015	3.769ArgLys: 3.769 ± 0.017	5.41ArgLeu: 5.41 ± 0.025	1.163ArgMet: 1.163 ± 0.009	2.085ArgAsn: 2.085 ± 0.013	3.451ArgPro: 3.451 ± 0.022	2.653ArgGln: 2.653 ± 0.014	4.45ArgArg: 4.45 ± 0.029	4.396ArgSer: 4.396 ± 0.031	2.89ArgThr: 2.89 ± 0.016	3.192ArgVal: 3.192 ± 0.017	0.696ArgTrp: 0.696 ± 0.007	1.434ArgTyr: 1.434 ± 0.012	0.006ArgXaa: 0.006 ± 0.001
Ser	5.381SerAla: 5.381 ± 0.021	1.805SerCys: 1.805 ± 0.017	3.915SerAsp: 3.915 ± 0.021	5.276SerGlu: 5.276 ± 0.025	3.016SerPhe: 3.016 ± 0.015	5.703SerGly: 5.703 ± 0.028	2.152SerHis: 2.152 ± 0.013	3.153SerIle: 3.153 ± 0.016	4.113SerLys: 4.113 ± 0.021	8.228SerLeu: 8.228 ± 0.032	1.568SerMet: 1.568 ± 0.01	2.628SerAsn: 2.628 ± 0.014	6.313SerPro: 6.313 ± 0.039	3.968SerGln: 3.968 ± 0.023	4.703SerArg: 4.703 ± 0.027	9.502SerSer: 9.502 ± 0.051	4.503SerThr: 4.503 ± 0.021	5.008SerVal: 5.008 ± 0.019	1.044SerTrp: 1.044 ± 0.009	2.01SerTyr: 2.01 ± 0.013	0.003SerXaa: 0.003 ± 0.0
Thr	3.761ThrAla: 3.761 ± 0.019	1.288ThrCys: 1.288 ± 0.015	2.465ThrAsp: 2.465 ± 0.014	3.604ThrGlu: 3.604 ± 0.02	2.073ThrPhe: 2.073 ± 0.013	3.554ThrGly: 3.554 ± 0.019	1.33ThrHis: 1.33 ± 0.011	2.319ThrIle: 2.319 ± 0.02	2.648ThrLys: 2.648 ± 0.016	5.268ThrLeu: 5.268 ± 0.022	1.076ThrMet: 1.076 ± 0.009	1.704ThrAsn: 1.704 ± 0.012	3.716ThrPro: 3.716 ± 0.023	2.312ThrGln: 2.312 ± 0.014	2.512ThrArg: 2.512 ± 0.015	4.695ThrSer: 4.695 ± 0.026	2.98ThrThr: 2.98 ± 0.027	3.9ThrVal: 3.9 ± 0.022	0.675ThrTrp: 0.675 ± 0.007	1.373ThrTyr: 1.373 ± 0.009	0.002ThrXaa: 0.002 ± 0.0
Val	4.269ValAla: 4.269 ± 0.019	1.434ValCys: 1.434 ± 0.012	2.91ValAsp: 2.91 ± 0.019	3.813ValGlu: 3.813 ± 0.02	2.344ValPhe: 2.344 ± 0.015	3.388ValGly: 3.388 ± 0.02	1.583ValHis: 1.583 ± 0.011	2.825ValIle: 2.825 ± 0.018	3.36ValLys: 3.36 ± 0.021	6.179ValLeu: 6.179 ± 0.025	1.332ValMet: 1.332 ± 0.012	2.21ValAsn: 2.21 ± 0.014	3.754ValPro: 3.754 ± 0.02	2.738ValGln: 2.738 ± 0.016	3.068ValArg: 3.068 ± 0.015	4.968ValSer: 4.968 ± 0.022	3.785ValThr: 3.785 ± 0.024	3.962ValVal: 3.962 ± 0.024	0.696ValTrp: 0.696 ± 0.007	1.57ValTyr: 1.57 ± 0.011	0.002ValXaa: 0.002 ± 0.0
Trp	0.778TrpAla: 0.778 ± 0.009	0.241TrpCys: 0.241 ± 0.004	0.631TrpAsp: 0.631 ± 0.007	0.791TrpGlu: 0.791 ± 0.006	0.435TrpPhe: 0.435 ± 0.006	0.728TrpGly: 0.728 ± 0.008	0.299TrpHis: 0.299 ± 0.004	0.512TrpIle: 0.512 ± 0.006	0.79TrpLys: 0.79 ± 0.008	1.166TrpLeu: 1.166 ± 0.011	0.301TrpMet: 0.301 ± 0.005	0.515TrpAsn: 0.515 ± 0.006	0.526TrpPro: 0.526 ± 0.007	0.515TrpGln: 0.515 ± 0.006	0.717TrpArg: 0.717 ± 0.007	0.842TrpSer: 0.842 ± 0.007	0.651TrpThr: 0.651 ± 0.007	0.673TrpVal: 0.673 ± 0.007	0.181TrpTrp: 0.181 ± 0.004	0.315TrpTyr: 0.315 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.368TyrAla: 1.368 ± 0.01	0.654TyrCys: 0.654 ± 0.008	1.229TyrAsp: 1.229 ± 0.01	1.657TyrGlu: 1.657 ± 0.014	1.174TyrPhe: 1.174 ± 0.009	1.616TyrGly: 1.616 ± 0.014	0.73TyrHis: 0.73 ± 0.007	1.299TyrIle: 1.299 ± 0.011	1.444TyrLys: 1.444 ± 0.019	2.566TyrLeu: 2.566 ± 0.016	0.557TyrMet: 0.557 ± 0.006	1.044TyrAsn: 1.044 ± 0.009	1.249TyrPro: 1.249 ± 0.01	1.212TyrGln: 1.212 ± 0.008	1.535TyrArg: 1.535 ± 0.011	2.133TyrSer: 2.133 ± 0.011	1.439TyrThr: 1.439 ± 0.012	1.532TyrVal: 1.532 ± 0.011	0.331TyrTrp: 0.331 ± 0.006	0.891TyrTyr: 0.891 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.012XaaAla: 0.012 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.009XaaGly: 0.009 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.003XaaLeu: 0.003 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.01XaaPro: 0.01 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.005XaaArg: 0.005 ± 0.001	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	3.702XaaXaa: 3.702 ± 0.272

Statistics based on 30929 proteins (17819806 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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