Amino acid dipepetide frequency for Colletotrichum fioriniae PJ7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.546AlaAla: 10.546 ± 0.067	1.112AlaCys: 1.112 ± 0.015	4.575AlaAsp: 4.575 ± 0.034	5.297AlaGlu: 5.297 ± 0.044	3.279AlaPhe: 3.279 ± 0.027	6.356AlaGly: 6.356 ± 0.034	1.75AlaHis: 1.75 ± 0.017	4.354AlaIle: 4.354 ± 0.03	4.276AlaLys: 4.276 ± 0.031	7.75AlaLeu: 7.75 ± 0.042	2.112AlaMet: 2.112 ± 0.02	3.148AlaAsn: 3.148 ± 0.023	5.215AlaPro: 5.215 ± 0.045	3.458AlaGln: 3.458 ± 0.027	4.825AlaArg: 4.825 ± 0.025	7.575AlaSer: 7.575 ± 0.04	5.722AlaThr: 5.722 ± 0.041	5.841AlaVal: 5.841 ± 0.03	1.308AlaTrp: 1.308 ± 0.016	2.232AlaTyr: 2.232 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.951CysAla: 0.951 ± 0.013	0.244CysCys: 0.244 ± 0.007	0.662CysAsp: 0.662 ± 0.012	0.578CysGlu: 0.578 ± 0.009	0.544CysPhe: 0.544 ± 0.01	0.964CysGly: 0.964 ± 0.014	0.312CysHis: 0.312 ± 0.007	0.683CysIle: 0.683 ± 0.01	0.518CysLys: 0.518 ± 0.01	1.223CysLeu: 1.223 ± 0.016	0.267CysMet: 0.267 ± 0.006	0.445CysAsn: 0.445 ± 0.01	0.665CysPro: 0.665 ± 0.014	0.446CysGln: 0.446 ± 0.008	0.727CysArg: 0.727 ± 0.011	0.896CysSer: 0.896 ± 0.013	0.692CysThr: 0.692 ± 0.011	0.795CysVal: 0.795 ± 0.011	0.214CysTrp: 0.214 ± 0.006	0.345CysTyr: 0.345 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.002AspAla: 5.002 ± 0.028	0.634AspCys: 0.634 ± 0.01	4.417AspAsp: 4.417 ± 0.042	4.433AspGlu: 4.433 ± 0.036	2.347AspPhe: 2.347 ± 0.018	4.301AspGly: 4.301 ± 0.028	1.223AspHis: 1.223 ± 0.014	2.939AspIle: 2.939 ± 0.021	2.461AspLys: 2.461 ± 0.021	4.976AspLeu: 4.976 ± 0.033	1.277AspMet: 1.277 ± 0.015	1.892AspAsn: 1.892 ± 0.018	3.253AspPro: 3.253 ± 0.024	1.805AspGln: 1.805 ± 0.018	2.955AspArg: 2.955 ± 0.027	3.951AspSer: 3.951 ± 0.03	2.923AspThr: 2.923 ± 0.024	3.823AspVal: 3.823 ± 0.028	0.947AspTrp: 0.947 ± 0.013	1.579AspTyr: 1.579 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.62GluAla: 5.62 ± 0.038	0.598GluCys: 0.598 ± 0.01	4.147GluAsp: 4.147 ± 0.036	5.332GluGlu: 5.332 ± 0.047	1.908GluPhe: 1.908 ± 0.019	3.777GluGly: 3.777 ± 0.026	1.32GluHis: 1.32 ± 0.015	2.891GluIle: 2.891 ± 0.023	3.667GluLys: 3.667 ± 0.031	4.869GluLeu: 4.869 ± 0.032	1.449GluMet: 1.449 ± 0.015	2.19GluAsn: 2.19 ± 0.016	2.845GluPro: 2.845 ± 0.036	2.229GluGln: 2.229 ± 0.019	3.683GluArg: 3.683 ± 0.032	4.101GluSer: 4.101 ± 0.03	3.519GluThr: 3.519 ± 0.027	3.678GluVal: 3.678 ± 0.027	0.892GluTrp: 0.892 ± 0.013	1.583GluTyr: 1.583 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	3.217PheAla: 3.217 ± 0.025	0.578PheCys: 0.578 ± 0.01	2.366PheAsp: 2.366 ± 0.019	2.164PheGlu: 2.164 ± 0.021	1.701PhePhe: 1.701 ± 0.018	3.026PheGly: 3.026 ± 0.028	0.902PheHis: 0.902 ± 0.012	1.815PheIle: 1.815 ± 0.018	1.55PheLys: 1.55 ± 0.017	3.426PheLeu: 3.426 ± 0.025	0.82PheMet: 0.82 ± 0.012	1.5PheAsn: 1.5 ± 0.015	1.98PhePro: 1.98 ± 0.017	1.384PheGln: 1.384 ± 0.015	1.924PheArg: 1.924 ± 0.017	3.038PheSer: 3.038 ± 0.023	2.223PheThr: 2.223 ± 0.022	2.466PheVal: 2.466 ± 0.021	0.679PheTrp: 0.679 ± 0.013	1.139PheTyr: 1.139 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.884GlyAla: 5.884 ± 0.037	0.929GlyCys: 0.929 ± 0.013	3.759GlyAsp: 3.759 ± 0.027	3.619GlyGlu: 3.619 ± 0.025	2.962GlyPhe: 2.962 ± 0.023	6.652GlyGly: 6.652 ± 0.06	1.709GlyHis: 1.709 ± 0.018	3.608GlyIle: 3.608 ± 0.027	3.481GlyLys: 3.481 ± 0.022	6.241GlyLeu: 6.241 ± 0.031	1.663GlyMet: 1.663 ± 0.02	2.714GlyAsn: 2.714 ± 0.026	3.546GlyPro: 3.546 ± 0.035	2.575GlyGln: 2.575 ± 0.021	4.097GlyArg: 4.097 ± 0.031	5.876GlySer: 5.876 ± 0.041	4.259GlyThr: 4.259 ± 0.041	4.569GlyVal: 4.569 ± 0.029	1.227GlyTrp: 1.227 ± 0.015	2.152GlyTyr: 2.152 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.822HisAla: 1.822 ± 0.017	0.335HisCys: 0.335 ± 0.008	1.284HisAsp: 1.284 ± 0.015	1.27HisGlu: 1.27 ± 0.014	0.919HisPhe: 0.919 ± 0.012	1.715HisGly: 1.715 ± 0.017	0.874HisHis: 0.874 ± 0.015	1.127HisIle: 1.127 ± 0.013	0.882HisLys: 0.882 ± 0.011	2.16HisLeu: 2.16 ± 0.018	0.515HisMet: 0.515 ± 0.009	0.837HisAsn: 0.837 ± 0.012	1.579HisPro: 1.579 ± 0.017	1.0HisGln: 1.0 ± 0.013	1.465HisArg: 1.465 ± 0.016	1.673HisSer: 1.673 ± 0.02	1.203HisThr: 1.203 ± 0.015	1.437HisVal: 1.437 ± 0.015	0.354HisTrp: 0.354 ± 0.006	0.667HisTyr: 0.667 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.281IleAla: 4.281 ± 0.029	0.705IleCys: 0.705 ± 0.012	2.816IleAsp: 2.816 ± 0.022	2.749IleGlu: 2.749 ± 0.024	1.991IlePhe: 1.991 ± 0.02	3.253IleGly: 3.253 ± 0.026	1.145IleHis: 1.145 ± 0.016	2.511IleIle: 2.511 ± 0.024	2.141IleLys: 2.141 ± 0.022	4.36IleLeu: 4.36 ± 0.032	1.053IleMet: 1.053 ± 0.013	1.758IleAsn: 1.758 ± 0.015	2.968IlePro: 2.968 ± 0.025	1.793IleGln: 1.793 ± 0.017	2.653IleArg: 2.653 ± 0.022	3.63IleSer: 3.63 ± 0.027	2.851IleThr: 2.851 ± 0.024	3.23IleVal: 3.23 ± 0.024	0.747IleTrp: 0.747 ± 0.011	1.31IleTyr: 1.31 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.442LysAla: 4.442 ± 0.034	0.503LysCys: 0.503 ± 0.009	2.826LysAsp: 2.826 ± 0.023	3.291LysGlu: 3.291 ± 0.031	1.51LysPhe: 1.51 ± 0.016	3.015LysGly: 3.015 ± 0.023	1.081LysHis: 1.081 ± 0.012	2.202LysIle: 2.202 ± 0.02	3.339LysLys: 3.339 ± 0.046	3.984LysLeu: 3.984 ± 0.024	1.049LysMet: 1.049 ± 0.013	1.729LysAsn: 1.729 ± 0.017	2.736LysPro: 2.736 ± 0.026	1.769LysGln: 1.769 ± 0.017	3.168LysArg: 3.168 ± 0.023	3.501LysSer: 3.501 ± 0.027	2.985LysThr: 2.985 ± 0.024	2.855LysVal: 2.855 ± 0.021	0.709LysTrp: 0.709 ± 0.009	1.341LysTyr: 1.341 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.03LeuAla: 8.03 ± 0.036	1.154LeuCys: 1.154 ± 0.015	4.966LeuAsp: 4.966 ± 0.031	5.245LeuGlu: 5.245 ± 0.038	3.283LeuPhe: 3.283 ± 0.024	6.074LeuGly: 6.074 ± 0.034	2.09LeuHis: 2.09 ± 0.019	3.785LeuIle: 3.785 ± 0.03	4.059LeuLys: 4.059 ± 0.027	7.996LeuLeu: 7.996 ± 0.054	1.803LeuMet: 1.803 ± 0.015	3.066LeuAsn: 3.066 ± 0.022	5.474LeuPro: 5.474 ± 0.049	3.556LeuGln: 3.556 ± 0.03	5.468LeuArg: 5.468 ± 0.034	6.932LeuSer: 6.932 ± 0.037	4.882LeuThr: 4.882 ± 0.039	5.421LeuVal: 5.421 ± 0.031	1.238LeuTrp: 1.238 ± 0.015	2.263LeuTyr: 2.263 ± 0.021	0.001LeuXaa: 0.001 ± 0.0
Met	2.391MetAla: 2.391 ± 0.019	0.249MetCys: 0.249 ± 0.006	1.233MetAsp: 1.233 ± 0.014	1.248MetGlu: 1.248 ± 0.012	0.794MetPhe: 0.794 ± 0.012	1.544MetGly: 1.544 ± 0.016	0.452MetHis: 0.452 ± 0.009	0.992MetIle: 0.992 ± 0.013	1.044MetLys: 1.044 ± 0.012	1.836MetLeu: 1.836 ± 0.017	0.623MetMet: 0.623 ± 0.01	0.815MetAsn: 0.815 ± 0.011	1.33MetPro: 1.33 ± 0.013	0.828MetGln: 0.828 ± 0.013	1.306MetArg: 1.306 ± 0.015	1.906MetSer: 1.906 ± 0.017	1.363MetThr: 1.363 ± 0.013	1.337MetVal: 1.337 ± 0.014	0.282MetTrp: 0.282 ± 0.007	0.528MetTyr: 0.528 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.199AsnAla: 3.199 ± 0.025	0.453AsnCys: 0.453 ± 0.009	1.99AsnAsp: 1.99 ± 0.017	1.942AsnGlu: 1.942 ± 0.016	1.447AsnPhe: 1.447 ± 0.015	3.163AsnGly: 3.163 ± 0.025	0.838AsnHis: 0.838 ± 0.011	1.974AsnIle: 1.974 ± 0.017	1.559AsnLys: 1.559 ± 0.016	3.234AsnLeu: 3.234 ± 0.023	0.86AsnMet: 0.86 ± 0.012	1.578AsnAsn: 1.578 ± 0.022	2.44AsnPro: 2.44 ± 0.022	1.305AsnGln: 1.305 ± 0.018	1.823AsnArg: 1.823 ± 0.017	2.663AsnSer: 2.663 ± 0.024	2.24AsnThr: 2.24 ± 0.02	2.341AsnVal: 2.341 ± 0.021	0.591AsnTrp: 0.591 ± 0.011	1.076AsnTyr: 1.076 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.706ProAla: 5.706 ± 0.052	0.511ProCys: 0.511 ± 0.01	3.206ProAsp: 3.206 ± 0.022	3.887ProGlu: 3.887 ± 0.033	2.088ProPhe: 2.088 ± 0.019	4.117ProGly: 4.117 ± 0.037	1.276ProHis: 1.276 ± 0.014	2.532ProIle: 2.532 ± 0.02	2.72ProLys: 2.72 ± 0.026	4.628ProLeu: 4.628 ± 0.027	1.138ProMet: 1.138 ± 0.016	2.187ProAsn: 2.187 ± 0.02	5.311ProPro: 5.311 ± 0.065	2.448ProGln: 2.448 ± 0.029	3.419ProArg: 3.419 ± 0.032	5.756ProSer: 5.756 ± 0.045	4.112ProThr: 4.112 ± 0.034	3.669ProVal: 3.669 ± 0.026	0.813ProTrp: 0.813 ± 0.012	1.491ProTyr: 1.491 ± 0.016	0.002ProXaa: 0.002 ± 0.0
Gln	3.486GlnAla: 3.486 ± 0.028	0.435GlnCys: 0.435 ± 0.008	2.026GlnAsp: 2.026 ± 0.017	2.244GlnGlu: 2.244 ± 0.019	1.244GlnPhe: 1.244 ± 0.014	2.397GlnGly: 2.397 ± 0.021	1.068GlnHis: 1.068 ± 0.013	1.783GlnIle: 1.783 ± 0.018	1.86GlnLys: 1.86 ± 0.018	3.269GlnLeu: 3.269 ± 0.026	0.891GlnMet: 0.891 ± 0.013	1.475GlnAsn: 1.475 ± 0.018	2.53GlnPro: 2.53 ± 0.03	2.569GlnGln: 2.569 ± 0.047	2.496GlnArg: 2.496 ± 0.022	2.944GlnSer: 2.944 ± 0.026	2.337GlnThr: 2.337 ± 0.028	2.152GlnVal: 2.152 ± 0.019	0.583GlnTrp: 0.583 ± 0.009	1.101GlnTyr: 1.101 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.572ArgAla: 4.572 ± 0.033	0.682ArgCys: 0.682 ± 0.012	3.369ArgAsp: 3.369 ± 0.031	3.612ArgGlu: 3.612 ± 0.03	2.087ArgPhe: 2.087 ± 0.017	3.756ArgGly: 3.756 ± 0.029	1.528ArgHis: 1.528 ± 0.019	2.716ArgIle: 2.716 ± 0.022	3.257ArgLys: 3.257 ± 0.024	5.177ArgLeu: 5.177 ± 0.038	1.272ArgMet: 1.272 ± 0.015	2.174ArgAsn: 2.174 ± 0.018	3.51ArgPro: 3.51 ± 0.027	2.527ArgGln: 2.527 ± 0.023	4.899ArgArg: 4.899 ± 0.037	4.505ArgSer: 4.505 ± 0.034	3.17ArgThr: 3.17 ± 0.025	3.293ArgVal: 3.293 ± 0.024	0.956ArgTrp: 0.956 ± 0.013	1.583ArgTyr: 1.583 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.838SerAla: 6.838 ± 0.04	0.857SerCys: 0.857 ± 0.014	4.14SerAsp: 4.14 ± 0.027	3.952SerGlu: 3.952 ± 0.03	3.045SerPhe: 3.045 ± 0.023	5.683SerGly: 5.683 ± 0.037	1.859SerHis: 1.859 ± 0.018	3.822SerIle: 3.822 ± 0.027	3.661SerLys: 3.661 ± 0.028	6.931SerLeu: 6.931 ± 0.035	1.739SerMet: 1.739 ± 0.017	2.9SerAsn: 2.9 ± 0.025	5.361SerPro: 5.361 ± 0.043	3.173SerGln: 3.173 ± 0.025	4.795SerArg: 4.795 ± 0.033	8.548SerSer: 8.548 ± 0.068	5.537SerThr: 5.537 ± 0.045	4.631SerVal: 4.631 ± 0.031	1.166SerTrp: 1.166 ± 0.014	2.032SerTyr: 2.032 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.613ThrAla: 5.613 ± 0.034	0.759ThrCys: 0.759 ± 0.012	2.913ThrAsp: 2.913 ± 0.021	3.177ThrGlu: 3.177 ± 0.024	2.355ThrPhe: 2.355 ± 0.019	4.376ThrGly: 4.376 ± 0.047	1.227ThrHis: 1.227 ± 0.016	3.143ThrIle: 3.143 ± 0.031	2.691ThrLys: 2.691 ± 0.023	5.181ThrLeu: 5.181 ± 0.043	1.234ThrMet: 1.234 ± 0.015	2.227ThrAsn: 2.227 ± 0.021	4.408ThrPro: 4.408 ± 0.035	2.109ThrGln: 2.109 ± 0.02	3.045ThrArg: 3.045 ± 0.021	5.415ThrSer: 5.415 ± 0.044	4.713ThrThr: 4.713 ± 0.06	3.882ThrVal: 3.882 ± 0.045	0.943ThrTrp: 0.943 ± 0.011	1.69ThrTyr: 1.69 ± 0.021	0.001ThrXaa: 0.001 ± 0.0
Val	5.706ValAla: 5.706 ± 0.03	0.819ValCys: 0.819 ± 0.012	3.799ValAsp: 3.799 ± 0.023	3.894ValGlu: 3.894 ± 0.027	2.601ValPhe: 2.601 ± 0.024	4.189ValGly: 4.189 ± 0.032	1.346ValHis: 1.346 ± 0.015	2.985ValIle: 2.985 ± 0.026	2.935ValLys: 2.935 ± 0.026	5.591ValLeu: 5.591 ± 0.04	1.332ValMet: 1.332 ± 0.015	2.283ValAsn: 2.283 ± 0.018	3.726ValPro: 3.726 ± 0.032	2.267ValGln: 2.267 ± 0.019	3.373ValArg: 3.373 ± 0.025	4.685ValSer: 4.685 ± 0.027	3.763ValThr: 3.763 ± 0.045	4.534ValVal: 4.534 ± 0.032	0.955ValTrp: 0.955 ± 0.012	1.762ValTyr: 1.762 ± 0.017	0.001ValXaa: 0.001 ± 0.0
Trp	1.249TrpAla: 1.249 ± 0.015	0.205TrpCys: 0.205 ± 0.006	0.959TrpAsp: 0.959 ± 0.013	0.868TrpGlu: 0.868 ± 0.012	0.588TrpPhe: 0.588 ± 0.011	1.006TrpGly: 1.006 ± 0.013	0.378TrpHis: 0.378 ± 0.009	0.779TrpIle: 0.779 ± 0.011	0.819TrpLys: 0.819 ± 0.01	1.38TrpLeu: 1.38 ± 0.015	0.394TrpMet: 0.394 ± 0.008	0.677TrpAsn: 0.677 ± 0.012	0.687TrpPro: 0.687 ± 0.01	0.604TrpGln: 0.604 ± 0.011	0.962TrpArg: 0.962 ± 0.012	1.109TrpSer: 1.109 ± 0.016	1.004TrpThr: 1.004 ± 0.012	0.941TrpVal: 0.941 ± 0.014	0.303TrpTrp: 0.303 ± 0.007	0.47TrpTyr: 0.47 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.178TyrAla: 2.178 ± 0.016	0.41TyrCys: 0.41 ± 0.008	1.688TyrAsp: 1.688 ± 0.018	1.496TyrGlu: 1.496 ± 0.015	1.207TyrPhe: 1.207 ± 0.015	2.155TyrGly: 2.155 ± 0.021	0.741TyrHis: 0.741 ± 0.01	1.305TyrIle: 1.305 ± 0.012	1.113TyrLys: 1.113 ± 0.013	2.573TyrLeu: 2.573 ± 0.02	0.612TyrMet: 0.612 ± 0.01	1.118TyrAsn: 1.118 ± 0.015	1.452TyrPro: 1.452 ± 0.015	1.046TyrGln: 1.046 ± 0.015	1.56TyrArg: 1.56 ± 0.014	1.964TyrSer: 1.964 ± 0.018	1.602TyrThr: 1.602 ± 0.02	1.651TyrVal: 1.651 ± 0.016	0.474TyrTrp: 0.474 ± 0.009	0.909TyrTyr: 0.909 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.028XaaXaa: 0.028 ± 0.005

Statistics based on 13759 proteins (6816730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---