Hepatitis B virus subtype adr (HBV)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Blubervirales; Hepadnaviridae; Orthohepadnavirus; Hepatitis B virus

Average proteome isoelectric point is 8.3

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q60GL5|Q60GL5_HBVDR Small S protein OS=Hepatitis B virus subtype adr OX=106820 GN=small S PE=4 SV=1
MM1 pKa = 7.75AARR4 pKa = 11.84XCCQLDD10 pKa = 3.39PARR13 pKa = 11.84DD14 pKa = 3.92VLCLRR19 pKa = 11.84PVGAEE24 pKa = 3.62SRR26 pKa = 11.84GRR28 pKa = 11.84PVSGPFGPLPSPSXSAVPADD48 pKa = 4.03HH49 pKa = 6.84GAHH52 pKa = 6.43LSLRR56 pKa = 11.84GLPVCAFSSAGPCALRR72 pKa = 11.84FTSARR77 pKa = 11.84RR78 pKa = 11.84MEE80 pKa = 4.46TTVNAHH86 pKa = 4.75QVLPKK91 pKa = 10.12VLHH94 pKa = 6.14KK95 pKa = 10.13RR96 pKa = 11.84TLGLSAMSTTDD107 pKa = 3.32LEE109 pKa = 5.55AYY111 pKa = 10.39FKK113 pKa = 11.19DD114 pKa = 4.14CLFKK118 pKa = 10.77DD119 pKa = 3.51WEE121 pKa = 4.29EE122 pKa = 4.03LGEE125 pKa = 4.19EE126 pKa = 3.99NRR128 pKa = 11.84LMIFVLGGCRR138 pKa = 11.84HH139 pKa = 6.36KK140 pKa = 10.73LVCSPAPCNFFTSAA154 pKa = 3.82

Molecular weight: 16.4 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q60GL4|Q60GL4_HBVDR Protein X OS=Hepatitis B virus subtype adr OX=106820 GN=X PE=3 SV=1
MM1 pKa = 8.03DD2 pKa = 5.37IDD4 pKa = 4.01PYY6 pKa = 11.31KK7 pKa = 10.77EE8 pKa = 4.0FGASVEE14 pKa = 4.32LLSFLPSDD22 pKa = 4.48FFPSARR28 pKa = 11.84DD29 pKa = 3.66LLDD32 pKa = 3.62TASALYY38 pKa = 10.4RR39 pKa = 11.84EE40 pKa = 4.55ALEE43 pKa = 4.62SPEE46 pKa = 4.18HH47 pKa = 6.65CSPHH51 pKa = 5.33HH52 pKa = 4.77TAIRR56 pKa = 11.84QAILCWGEE64 pKa = 4.13LMNLATWVGSNLXDD78 pKa = 4.03PASRR82 pKa = 11.84EE83 pKa = 4.09LVVGYY88 pKa = 10.73VNVNMGLKK96 pKa = 10.05FRR98 pKa = 11.84QLLWFHH104 pKa = 6.79ISCLTFGRR112 pKa = 11.84EE113 pKa = 3.77TVLEE117 pKa = 4.1YY118 pKa = 10.79LVSFGVWIRR127 pKa = 11.84TPAPYY132 pKa = 9.94RR133 pKa = 11.84PPNAPILSTLPEE145 pKa = 4.25TTVVRR150 pKa = 11.84QRR152 pKa = 11.84GRR154 pKa = 11.84SLRR157 pKa = 11.84RR158 pKa = 11.84RR159 pKa = 11.84TPSPRR164 pKa = 11.84RR165 pKa = 11.84RR166 pKa = 11.84RR167 pKa = 11.84SQSPRR172 pKa = 11.84RR173 pKa = 11.84RR174 pKa = 11.84RR175 pKa = 11.84SKK177 pKa = 10.98SRR179 pKa = 11.84DD180 pKa = 3.48SQCC183 pKa = 4.02

Molecular weight: 20.9 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

563

154

226

187.7

20.84

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.039 ± 1.747

4.796 ± 1.084

2.842 ± 0.773

3.552 ± 1.161

5.684 ± 0.741

5.506 ± 0.604

1.776 ± 0.711

3.73 ± 1.363

1.954 ± 0.464

13.321 ± 1.334

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.309 ± 0.277

2.309 ± 0.178

9.236 ± 0.71

2.487 ± 0.432

7.282 ± 2.612

9.947 ± 0.533

6.039 ± 0.776

5.329 ± 0.692

3.197 ± 1.335

1.776 ± 0.45
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski