Amino acid dipepetide frequency for Trichechus manatus papillomavirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.976AlaAla: 6.976 ± 1.052
1.231AlaCys: 1.231 ± 0.692
4.514AlaAsp: 4.514 ± 1.046
2.462AlaGlu: 2.462 ± 0.56
2.872AlaPhe: 2.872 ± 1.255
3.693AlaGly: 3.693 ± 0.726
0.0AlaHis: 0.0 ± 0.0
2.872AlaIle: 2.872 ± 0.487
3.283AlaLys: 3.283 ± 1.019
3.693AlaLeu: 3.693 ± 1.09
0.41AlaMet: 0.41 ± 0.363
1.231AlaAsn: 1.231 ± 0.364
3.693AlaPro: 3.693 ± 1.521
3.693AlaGln: 3.693 ± 1.406
3.693AlaArg: 3.693 ± 1.944
6.976AlaSer: 6.976 ± 1.654
4.514AlaThr: 4.514 ± 0.712
4.514AlaVal: 4.514 ± 0.919
0.821AlaTrp: 0.821 ± 0.393
3.283AlaTyr: 3.283 ± 0.896
0.0AlaXaa: 0.0 ± 0.0
Cys
0.821CysAla: 0.821 ± 0.478
0.821CysCys: 0.821 ± 0.616
0.41CysAsp: 0.41 ± 0.47
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.231CysGly: 1.231 ± 0.999
0.0CysHis: 0.0 ± 0.0
1.231CysIle: 1.231 ± 0.924
2.052CysLys: 2.052 ± 1.203
2.872CysLeu: 2.872 ± 1.96
0.821CysMet: 0.821 ± 0.411
0.0CysAsn: 0.0 ± 0.0
1.641CysPro: 1.641 ± 0.78
0.0CysGln: 0.0 ± 0.0
3.693CysArg: 3.693 ± 0.789
1.641CysSer: 1.641 ± 0.47
2.052CysThr: 2.052 ± 1.034
0.0CysVal: 0.0 ± 0.0
0.41CysTrp: 0.41 ± 0.308
0.821CysTyr: 0.821 ± 0.411
0.0CysXaa: 0.0 ± 0.0
Asp
3.283AspAla: 3.283 ± 0.825
0.821AspCys: 0.821 ± 0.393
4.514AspAsp: 4.514 ± 1.452
2.872AspGlu: 2.872 ± 1.314
2.462AspPhe: 2.462 ± 1.026
5.334AspGly: 5.334 ± 0.968
1.641AspHis: 1.641 ± 0.572
4.924AspIle: 4.924 ± 2.107
2.052AspLys: 2.052 ± 0.985
7.796AspLeu: 7.796 ± 1.537
0.821AspMet: 0.821 ± 0.393
4.514AspAsn: 4.514 ± 1.317
5.334AspPro: 5.334 ± 1.841
2.462AspGln: 2.462 ± 0.945
4.103AspArg: 4.103 ± 1.256
6.155AspSer: 6.155 ± 1.684
4.514AspThr: 4.514 ± 0.948
2.462AspVal: 2.462 ± 1.169
1.231AspTrp: 1.231 ± 0.569
0.821AspTyr: 0.821 ± 0.47
0.0AspXaa: 0.0 ± 0.0
Glu
2.462GluAla: 2.462 ± 0.78
1.641GluCys: 1.641 ± 0.723
4.514GluAsp: 4.514 ± 1.507
2.872GluGlu: 2.872 ± 1.999
0.41GluPhe: 0.41 ± 0.308
5.334GluGly: 5.334 ± 1.453
0.41GluHis: 0.41 ± 0.362
2.462GluIle: 2.462 ± 0.943
0.821GluLys: 0.821 ± 0.477
4.103GluLeu: 4.103 ± 1.882
0.821GluMet: 0.821 ± 0.358
1.231GluAsn: 1.231 ± 0.535
3.283GluPro: 3.283 ± 0.98
4.103GluGln: 4.103 ± 1.01
4.103GluArg: 4.103 ± 1.262
2.052GluSer: 2.052 ± 0.712
4.103GluThr: 4.103 ± 1.148
3.283GluVal: 3.283 ± 0.856
0.41GluTrp: 0.41 ± 0.308
1.231GluTyr: 1.231 ± 0.863
0.0GluXaa: 0.0 ± 0.0
Phe
3.283PheAla: 3.283 ± 0.592
0.821PheCys: 0.821 ± 0.478
3.693PheAsp: 3.693 ± 1.5
2.462PheGlu: 2.462 ± 0.913
1.641PhePhe: 1.641 ± 0.6
2.462PheGly: 2.462 ± 1.034
0.41PheHis: 0.41 ± 0.363
0.821PheIle: 0.821 ± 0.393
1.641PheLys: 1.641 ± 0.96
6.155PheLeu: 6.155 ± 0.788
0.0PheMet: 0.0 ± 0.0
1.641PheAsn: 1.641 ± 1.08
1.231PhePro: 1.231 ± 0.744
0.0PheGln: 0.0 ± 0.0
1.641PheArg: 1.641 ± 0.877
1.231PheSer: 1.231 ± 0.692
3.283PheThr: 3.283 ± 1.011
0.0PheVal: 0.0 ± 0.0
1.231PheTrp: 1.231 ± 0.606
0.821PheTyr: 0.821 ± 0.53
0.0PheXaa: 0.0 ± 0.0
Gly
6.565GlyAla: 6.565 ± 2.4
1.231GlyCys: 1.231 ± 0.671
6.155GlyAsp: 6.155 ± 0.884
4.924GlyGlu: 4.924 ± 0.518
2.462GlyPhe: 2.462 ± 0.559
9.848GlyGly: 9.848 ± 3.94
1.641GlyHis: 1.641 ± 0.624
2.872GlyIle: 2.872 ± 0.733
0.821GlyLys: 0.821 ± 0.616
4.924GlyLeu: 4.924 ± 1.487
0.41GlyMet: 0.41 ± 0.395
3.283GlyAsn: 3.283 ± 0.912
3.693GlyPro: 3.693 ± 1.291
2.462GlyGln: 2.462 ± 0.78
8.207GlyArg: 8.207 ± 2.35
3.283GlySer: 3.283 ± 0.959
3.693GlyThr: 3.693 ± 1.23
5.334GlyVal: 5.334 ± 1.233
0.0GlyTrp: 0.0 ± 0.0
1.231GlyTyr: 1.231 ± 0.342
0.0GlyXaa: 0.0 ± 0.0
His
1.231HisAla: 1.231 ± 0.376
0.821HisCys: 0.821 ± 0.478
1.641HisAsp: 1.641 ± 1.146
0.821HisGlu: 0.821 ± 0.46
1.641HisPhe: 1.641 ± 0.448
1.641HisGly: 1.641 ± 0.5
0.0HisHis: 0.0 ± 0.0
2.052HisIle: 2.052 ± 1.183
0.821HisLys: 0.821 ± 0.677
0.41HisLeu: 0.41 ± 0.308
0.41HisMet: 0.41 ± 0.348
0.821HisAsn: 0.821 ± 0.393
2.052HisPro: 2.052 ± 0.672
1.641HisGln: 1.641 ± 0.641
2.462HisArg: 2.462 ± 1.385
1.231HisSer: 1.231 ± 0.657
0.821HisThr: 0.821 ± 0.46
1.641HisVal: 1.641 ± 0.797
0.41HisTrp: 0.41 ± 0.338
0.41HisTyr: 0.41 ± 0.338
0.0HisXaa: 0.0 ± 0.0
Ile
1.231IleAla: 1.231 ± 0.375
2.052IleCys: 2.052 ± 1.041
2.872IleAsp: 2.872 ± 0.977
2.052IleGlu: 2.052 ± 0.678
1.231IlePhe: 1.231 ± 0.744
2.872IleGly: 2.872 ± 1.333
2.462IleHis: 2.462 ± 0.613
1.641IleIle: 1.641 ± 1.446
0.41IleLys: 0.41 ± 0.363
3.693IleLeu: 3.693 ± 0.79
1.231IleMet: 1.231 ± 0.677
1.231IleAsn: 1.231 ± 0.342
3.283IlePro: 3.283 ± 0.959
2.052IleGln: 2.052 ± 0.434
2.052IleArg: 2.052 ± 1.005
5.334IleSer: 5.334 ± 1.841
2.462IleThr: 2.462 ± 1.157
2.872IleVal: 2.872 ± 1.102
0.41IleTrp: 0.41 ± 0.338
1.641IleTyr: 1.641 ± 0.79
0.0IleXaa: 0.0 ± 0.0
Lys
2.872LysAla: 2.872 ± 0.441
1.641LysCys: 1.641 ± 0.426
1.641LysAsp: 1.641 ± 0.752
2.462LysGlu: 2.462 ± 0.901
0.821LysPhe: 0.821 ± 0.393
1.641LysGly: 1.641 ± 0.552
2.052LysHis: 2.052 ± 1.081
0.821LysIle: 0.821 ± 0.393
1.641LysLys: 1.641 ± 0.552
2.462LysLeu: 2.462 ± 0.938
0.41LysMet: 0.41 ± 0.675
0.821LysAsn: 0.821 ± 0.411
0.821LysPro: 0.821 ± 0.393
1.641LysGln: 1.641 ± 0.635
4.103LysArg: 4.103 ± 0.659
2.052LysSer: 2.052 ± 1.065
2.052LysThr: 2.052 ± 0.77
2.052LysVal: 2.052 ± 1.034
1.641LysTrp: 1.641 ± 0.857
1.641LysTyr: 1.641 ± 0.684
0.0LysXaa: 0.0 ± 0.0
Leu
6.155LeuAla: 6.155 ± 2.208
1.231LeuCys: 1.231 ± 0.797
7.386LeuAsp: 7.386 ± 1.46
3.693LeuGlu: 3.693 ± 1.219
3.693LeuPhe: 3.693 ± 1.069
6.565LeuGly: 6.565 ± 1.451
4.103LeuHis: 4.103 ± 1.495
2.052LeuIle: 2.052 ± 0.723
4.924LeuLys: 4.924 ± 1.072
9.848LeuLeu: 9.848 ± 2.17
2.052LeuMet: 2.052 ± 0.687
2.462LeuAsn: 2.462 ± 0.795
3.693LeuPro: 3.693 ± 0.692
7.796LeuGln: 7.796 ± 2.055
4.103LeuArg: 4.103 ± 1.307
7.386LeuSer: 7.386 ± 1.241
6.155LeuThr: 6.155 ± 1.804
5.334LeuVal: 5.334 ± 0.814
0.41LeuTrp: 0.41 ± 0.338
4.924LeuTyr: 4.924 ± 0.495
0.0LeuXaa: 0.0 ± 0.0
Met
0.821MetAla: 0.821 ± 0.393
0.41MetCys: 0.41 ± 0.338
2.052MetAsp: 2.052 ± 0.61
0.821MetGlu: 0.821 ± 0.395
0.41MetPhe: 0.41 ± 0.362
0.821MetGly: 0.821 ± 0.727
0.821MetHis: 0.821 ± 0.608
0.821MetIle: 0.821 ± 0.477
0.0MetLys: 0.0 ± 0.0
0.821MetLeu: 0.821 ± 0.411
0.41MetMet: 0.41 ± 0.338
0.821MetAsn: 0.821 ± 0.393
0.821MetPro: 0.821 ± 0.364
1.231MetGln: 1.231 ± 0.924
0.41MetArg: 0.41 ± 0.338
0.821MetSer: 0.821 ± 0.616
0.821MetThr: 0.821 ± 0.727
1.231MetVal: 1.231 ± 0.606
0.0MetTrp: 0.0 ± 0.0
0.821MetTyr: 0.821 ± 0.388
0.0MetXaa: 0.0 ± 0.0
Asn
1.641AsnAla: 1.641 ± 0.51
0.41AsnCys: 0.41 ± 0.308
1.231AsnAsp: 1.231 ± 0.469
1.641AsnGlu: 1.641 ± 1.232
2.052AsnPhe: 2.052 ± 1.065
0.821AsnGly: 0.821 ± 0.393
0.0AsnHis: 0.0 ± 0.0
2.052AsnIle: 2.052 ± 0.755
0.0AsnLys: 0.0 ± 0.0
3.283AsnLeu: 3.283 ± 0.766
1.231AsnMet: 1.231 ± 0.631
2.462AsnAsn: 2.462 ± 0.461
3.693AsnPro: 3.693 ± 0.583
1.231AsnGln: 1.231 ± 1.015
2.462AsnArg: 2.462 ± 1.323
2.872AsnSer: 2.872 ± 0.762
3.693AsnThr: 3.693 ± 0.948
1.641AsnVal: 1.641 ± 0.552
0.821AsnTrp: 0.821 ± 0.477
1.641AsnTyr: 1.641 ± 0.678
0.0AsnXaa: 0.0 ± 0.0
Pro
6.976ProAla: 6.976 ± 1.797
0.41ProCys: 0.41 ± 0.395
4.514ProAsp: 4.514 ± 1.944
5.334ProGlu: 5.334 ± 0.784
0.821ProPhe: 0.821 ± 0.395
2.872ProGly: 2.872 ± 1.035
2.052ProHis: 2.052 ± 0.672
2.462ProIle: 2.462 ± 0.477
2.872ProLys: 2.872 ± 0.798
6.155ProLeu: 6.155 ± 1.94
0.0ProMet: 0.0 ± 0.0
2.872ProAsn: 2.872 ± 0.692
7.386ProPro: 7.386 ± 1.796
1.641ProGln: 1.641 ± 0.624
6.565ProArg: 6.565 ± 1.559
6.155ProSer: 6.155 ± 2.332
5.334ProThr: 5.334 ± 2.066
4.924ProVal: 4.924 ± 1.485
0.41ProTrp: 0.41 ± 0.338
2.052ProTyr: 2.052 ± 1.205
0.0ProXaa: 0.0 ± 0.0
Gln
2.462GlnAla: 2.462 ± 0.685
0.0GlnCys: 0.0 ± 0.0
4.103GlnAsp: 4.103 ± 0.805
2.462GlnGlu: 2.462 ± 1.512
2.052GlnPhe: 2.052 ± 0.679
2.872GlnGly: 2.872 ± 1.4
0.821GlnHis: 0.821 ± 0.388
2.052GlnIle: 2.052 ± 0.269
0.0GlnLys: 0.0 ± 0.0
4.924GlnLeu: 4.924 ± 1.248
0.821GlnMet: 0.821 ± 0.393
2.872GlnAsn: 2.872 ± 0.762
3.283GlnPro: 3.283 ± 1.436
2.052GlnGln: 2.052 ± 1.167
2.462GlnArg: 2.462 ± 0.461
2.052GlnSer: 2.052 ± 0.454
2.462GlnThr: 2.462 ± 0.559
1.641GlnVal: 1.641 ± 0.583
0.41GlnTrp: 0.41 ± 0.308
2.462GlnTyr: 2.462 ± 0.924
0.0GlnXaa: 0.0 ± 0.0
Arg
2.462ArgAla: 2.462 ± 0.417
2.872ArgCys: 2.872 ± 1.351
2.872ArgAsp: 2.872 ± 0.888
0.821ArgGlu: 0.821 ± 0.592
3.283ArgPhe: 3.283 ± 0.895
7.386ArgGly: 7.386 ± 3.168
1.641ArgHis: 1.641 ± 0.6
2.462ArgIle: 2.462 ± 0.763
4.103ArgLys: 4.103 ± 0.768
7.796ArgLeu: 7.796 ± 0.95
0.41ArgMet: 0.41 ± 0.288
1.641ArgAsn: 1.641 ± 0.921
9.438ArgPro: 9.438 ± 2.782
2.052ArgGln: 2.052 ± 0.755
4.924ArgArg: 4.924 ± 0.906
4.924ArgSer: 4.924 ± 1.41
4.924ArgThr: 4.924 ± 1.008
3.693ArgVal: 3.693 ± 0.601
1.231ArgTrp: 1.231 ± 0.687
3.283ArgTyr: 3.283 ± 1.113
0.0ArgXaa: 0.0 ± 0.0
Ser
4.103SerAla: 4.103 ± 0.525
1.641SerCys: 1.641 ± 0.726
5.334SerAsp: 5.334 ± 1.571
3.283SerGlu: 3.283 ± 0.857
4.924SerPhe: 4.924 ± 1.614
5.745SerGly: 5.745 ± 1.201
2.052SerHis: 2.052 ± 0.998
3.283SerIle: 3.283 ± 0.708
3.283SerLys: 3.283 ± 1.565
5.745SerLeu: 5.745 ± 1.276
1.641SerMet: 1.641 ± 0.877
2.052SerAsn: 2.052 ± 0.78
6.565SerPro: 6.565 ± 0.72
2.052SerGln: 2.052 ± 0.875
3.283SerArg: 3.283 ± 0.786
6.155SerSer: 6.155 ± 2.467
8.617SerThr: 8.617 ± 2.609
5.334SerVal: 5.334 ± 0.774
1.641SerTrp: 1.641 ± 0.702
0.821SerTyr: 0.821 ± 0.477
0.0SerXaa: 0.0 ± 0.0
Thr
3.693ThrAla: 3.693 ± 1.076
1.231ThrCys: 1.231 ± 0.503
4.924ThrAsp: 4.924 ± 1.622
4.103ThrGlu: 4.103 ± 1.289
2.052ThrPhe: 2.052 ± 0.269
6.155ThrGly: 6.155 ± 1.273
0.821ThrHis: 0.821 ± 0.46
2.872ThrIle: 2.872 ± 2.07
2.462ThrLys: 2.462 ± 0.866
6.565ThrLeu: 6.565 ± 0.807
1.231ThrMet: 1.231 ± 0.692
2.462ThrAsn: 2.462 ± 0.417
5.745ThrPro: 5.745 ± 1.494
2.462ThrGln: 2.462 ± 0.78
3.693ThrArg: 3.693 ± 0.925
9.027ThrSer: 9.027 ± 1.37
4.514ThrThr: 4.514 ± 2.664
6.155ThrVal: 6.155 ± 0.761
1.231ThrTrp: 1.231 ± 0.687
1.641ThrTyr: 1.641 ± 0.702
0.0ThrXaa: 0.0 ± 0.0
Val
3.283ValAla: 3.283 ± 1.063
0.41ValCys: 0.41 ± 0.47
4.103ValAsp: 4.103 ± 1.147
4.103ValGlu: 4.103 ± 0.601
0.41ValPhe: 0.41 ± 0.363
2.872ValGly: 2.872 ± 0.896
0.821ValHis: 0.821 ± 0.723
2.462ValIle: 2.462 ± 0.466
2.872ValLys: 2.872 ± 0.881
7.386ValLeu: 7.386 ± 1.575
0.0ValMet: 0.0 ± 0.0
1.641ValAsn: 1.641 ± 0.448
4.514ValPro: 4.514 ± 1.075
1.231ValGln: 1.231 ± 0.643
5.334ValArg: 5.334 ± 1.338
5.334ValSer: 5.334 ± 1.444
4.924ValThr: 4.924 ± 1.285
3.693ValVal: 3.693 ± 1.242
0.41ValTrp: 0.41 ± 0.363
1.641ValTyr: 1.641 ± 1.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.641TrpAla: 1.641 ± 0.552
0.41TrpCys: 0.41 ± 0.395
0.821TrpAsp: 0.821 ± 0.393
0.41TrpGlu: 0.41 ± 0.338
0.0TrpPhe: 0.0 ± 0.0
0.41TrpGly: 0.41 ± 0.338
0.41TrpHis: 0.41 ± 0.363
0.821TrpIle: 0.821 ± 0.364
0.41TrpLys: 0.41 ± 0.395
2.872TrpLeu: 2.872 ± 0.875
0.0TrpMet: 0.0 ± 0.0
0.41TrpAsn: 0.41 ± 0.363
0.0TrpPro: 0.0 ± 0.0
1.231TrpGln: 1.231 ± 0.631
1.641TrpArg: 1.641 ± 0.702
0.41TrpSer: 0.41 ± 0.395
2.052TrpThr: 2.052 ± 0.88
0.821TrpVal: 0.821 ± 0.616
0.41TrpTrp: 0.41 ± 0.338
0.41TrpTyr: 0.41 ± 0.308
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.462TyrAla: 2.462 ± 0.847
0.41TyrCys: 0.41 ± 0.308
0.821TyrAsp: 0.821 ± 0.411
2.052TyrGlu: 2.052 ± 0.65
1.231TyrPhe: 1.231 ± 0.375
2.462TyrGly: 2.462 ± 0.662
0.821TyrHis: 0.821 ± 0.477
2.052TyrIle: 2.052 ± 0.59
1.231TyrLys: 1.231 ± 0.687
2.462TyrLeu: 2.462 ± 0.794
1.641TyrMet: 1.641 ± 0.822
0.41TyrAsn: 0.41 ± 0.363
1.641TyrPro: 1.641 ± 0.837
1.231TyrGln: 1.231 ± 0.479
3.283TyrArg: 3.283 ± 0.873
2.462TyrSer: 2.462 ± 0.766
2.052TyrThr: 2.052 ± 1.009
0.821TyrVal: 0.821 ± 0.727
2.052TyrTrp: 2.052 ± 0.59
2.872TyrTyr: 2.872 ± 1.249
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2438 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski