Human papillomavirus 107

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 2

Average proteome isoelectric point is 5.92

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A3RKL8|A3RKL8_9PAPI Replication protein E1 OS=Human papillomavirus 107 OX=427343 GN=E1 PE=3 SV=1
MM1 pKa = 7.43IGKK4 pKa = 8.97EE5 pKa = 3.83VTIPDD10 pKa = 3.41IVLEE14 pKa = 4.05EE15 pKa = 4.22LQEE18 pKa = 3.99LAQPIDD24 pKa = 3.28LHH26 pKa = 8.37CYY28 pKa = 9.94EE29 pKa = 5.38EE30 pKa = 5.35LPEE33 pKa = 5.28LPDD36 pKa = 3.51ATSEE40 pKa = 4.13EE41 pKa = 4.65SEE43 pKa = 4.45EE44 pKa = 4.04EE45 pKa = 4.34PEE47 pKa = 4.39RR48 pKa = 11.84IPYY51 pKa = 9.63KK52 pKa = 10.4IVVPCSGCPVKK63 pKa = 10.75LRR65 pKa = 11.84LYY67 pKa = 10.77VFATHH72 pKa = 6.68FGIRR76 pKa = 11.84ALQDD80 pKa = 3.52LLLQEE85 pKa = 4.41VQLICPQCRR94 pKa = 11.84EE95 pKa = 4.38AIRR98 pKa = 11.84HH99 pKa = 5.56GGQQ102 pKa = 2.81

Molecular weight: 11.58 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A3RKM0|A3RKM0_9PAPI E4 protein OS=Human papillomavirus 107 OX=427343 GN=E4 PE=4 SV=1
MM1 pKa = 7.02EE2 pKa = 4.6TLSEE6 pKa = 4.42RR7 pKa = 11.84FTALQDD13 pKa = 3.42KK14 pKa = 10.91LMDD17 pKa = 3.74IYY19 pKa = 11.21EE20 pKa = 4.7SGLEE24 pKa = 3.92TLEE27 pKa = 3.88VQIEE31 pKa = 4.05HH32 pKa = 6.09WQLLRR37 pKa = 11.84QEE39 pKa = 4.14QVLLNFARR47 pKa = 11.84RR48 pKa = 11.84NGILRR53 pKa = 11.84LGYY56 pKa = 10.28QPVPSLATSEE66 pKa = 4.44TKK68 pKa = 10.75AKK70 pKa = 10.47DD71 pKa = 3.72AIGMVLMLQSLQNSKK86 pKa = 10.51YY87 pKa = 10.76AEE89 pKa = 4.29EE90 pKa = 4.14TWSLVQTSLEE100 pKa = 4.44TVRR103 pKa = 11.84SPPEE107 pKa = 3.54NCFKK111 pKa = 10.96KK112 pKa = 10.33EE113 pKa = 3.83PQTIEE118 pKa = 3.98VVFDD122 pKa = 3.78GDD124 pKa = 3.59PEE126 pKa = 3.88NRR128 pKa = 11.84MIYY131 pKa = 7.92TVWNWIYY138 pKa = 10.13FQNTEE143 pKa = 5.24DD144 pKa = 2.7IWQKK148 pKa = 10.8VKK150 pKa = 10.8GHH152 pKa = 5.92VDD154 pKa = 3.43YY155 pKa = 11.43EE156 pKa = 4.44GAFYY160 pKa = 10.51MEE162 pKa = 4.83GTHH165 pKa = 4.8KK166 pKa = 10.13HH167 pKa = 5.31YY168 pKa = 10.84YY169 pKa = 9.67IKK171 pKa = 10.76FEE173 pKa = 4.05NDD175 pKa = 2.66ANRR178 pKa = 11.84FSATGLWEE186 pKa = 3.8VHH188 pKa = 5.52VNQDD192 pKa = 3.28TVFTPVTSSTSQAGSRR208 pKa = 11.84LSPLPSDD215 pKa = 3.55PTSRR219 pKa = 11.84RR220 pKa = 11.84PSPSISTVTTKK231 pKa = 9.18QRR233 pKa = 11.84RR234 pKa = 11.84YY235 pKa = 8.53GRR237 pKa = 11.84KK238 pKa = 8.92RR239 pKa = 11.84SSPTATTTGRR249 pKa = 11.84QRR251 pKa = 11.84QRR253 pKa = 11.84TRR255 pKa = 11.84EE256 pKa = 4.05TQQKK260 pKa = 6.95TKK262 pKa = 9.38RR263 pKa = 11.84TRR265 pKa = 11.84SRR267 pKa = 11.84SRR269 pKa = 11.84TKK271 pKa = 10.55SSTRR275 pKa = 11.84SRR277 pKa = 11.84NRR279 pKa = 11.84SRR281 pKa = 11.84SRR283 pKa = 11.84SRR285 pKa = 11.84SSGRR289 pKa = 11.84QDD291 pKa = 2.64TDD293 pKa = 2.9ATKK296 pKa = 10.86GRR298 pKa = 11.84GQGGRR303 pKa = 11.84GRR305 pKa = 11.84EE306 pKa = 3.73RR307 pKa = 11.84EE308 pKa = 3.86RR309 pKa = 11.84EE310 pKa = 3.82RR311 pKa = 11.84EE312 pKa = 4.01RR313 pKa = 11.84EE314 pKa = 3.87RR315 pKa = 11.84EE316 pKa = 3.88RR317 pKa = 11.84ADD319 pKa = 3.21TSNRR323 pKa = 11.84TSRR326 pKa = 11.84GGGRR330 pKa = 11.84SGRR333 pKa = 11.84RR334 pKa = 11.84PQTRR338 pKa = 11.84SRR340 pKa = 11.84SRR342 pKa = 11.84SGGSPDD348 pKa = 3.23RR349 pKa = 11.84VGIAPSEE356 pKa = 4.27VGRR359 pKa = 11.84TLQSVGTTGHH369 pKa = 5.88GRR371 pKa = 11.84LGRR374 pKa = 11.84LLDD377 pKa = 3.81EE378 pKa = 5.48AKK380 pKa = 10.56DD381 pKa = 3.64PPVILLRR388 pKa = 11.84GEE390 pKa = 4.13ANQLKK395 pKa = 9.98CYY397 pKa = 10.28RR398 pKa = 11.84FRR400 pKa = 11.84ARR402 pKa = 11.84KK403 pKa = 8.23KK404 pKa = 9.45HH405 pKa = 5.36KK406 pKa = 10.6GNYY409 pKa = 9.43KK410 pKa = 9.98YY411 pKa = 10.7FSSTWSWIGEE421 pKa = 4.06HH422 pKa = 6.4SNDD425 pKa = 3.59RR426 pKa = 11.84IGRR429 pKa = 11.84ARR431 pKa = 11.84MLVSFTSTHH440 pKa = 4.27QRR442 pKa = 11.84EE443 pKa = 4.28MFLDD447 pKa = 3.92TMKK450 pKa = 10.78LPQGVDD456 pKa = 2.63WSYY459 pKa = 12.19GNFDD463 pKa = 3.58SLL465 pKa = 4.67

Molecular weight: 53.48 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2550

102

607

364.3

41.15

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.451 ± 0.433

1.804 ± 0.652

5.725 ± 0.527

7.176 ± 0.915

4.353 ± 0.73

6.627 ± 0.871

2.0 ± 0.214

4.706 ± 0.895

4.902 ± 0.76

8.667 ± 0.914

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.843 ± 0.527

4.275 ± 0.842

6.196 ± 1.239

5.373 ± 0.275

6.863 ± 1.25

7.49 ± 0.931

6.431 ± 0.812

5.882 ± 0.906

1.255 ± 0.369

2.98 ± 0.271
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski