Amino acid dipepetide frequency for Schizopora paradoxa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.005AlaAla: 7.005 ± 0.046
1.156AlaCys: 1.156 ± 0.014
3.731AlaAsp: 3.731 ± 0.026
4.339AlaGlu: 4.339 ± 0.03
3.399AlaPhe: 3.399 ± 0.024
4.832AlaGly: 4.832 ± 0.027
1.869AlaHis: 1.869 ± 0.018
4.143AlaIle: 4.143 ± 0.026
3.787AlaLys: 3.787 ± 0.028
8.093AlaLeu: 8.093 ± 0.039
1.806AlaMet: 1.806 ± 0.015
2.908AlaAsn: 2.908 ± 0.022
4.432AlaPro: 4.432 ± 0.031
2.941AlaGln: 2.941 ± 0.022
4.866AlaArg: 4.866 ± 0.029
7.774AlaSer: 7.774 ± 0.043
4.63AlaThr: 4.63 ± 0.032
5.05AlaVal: 5.05 ± 0.028
1.004AlaTrp: 1.004 ± 0.013
1.985AlaTyr: 1.985 ± 0.018
0.0AlaXaa: 0.0 ± 0.0
Cys
1.093CysAla: 1.093 ± 0.014
0.304CysCys: 0.304 ± 0.008
0.772CysAsp: 0.772 ± 0.011
0.744CysGlu: 0.744 ± 0.01
0.637CysPhe: 0.637 ± 0.009
0.921CysGly: 0.921 ± 0.012
0.336CysHis: 0.336 ± 0.007
0.793CysIle: 0.793 ± 0.011
0.655CysLys: 0.655 ± 0.01
1.419CysLeu: 1.419 ± 0.015
0.316CysMet: 0.316 ± 0.007
0.497CysAsn: 0.497 ± 0.009
0.78CysPro: 0.78 ± 0.012
0.468CysGln: 0.468 ± 0.009
0.944CysArg: 0.944 ± 0.012
1.216CysSer: 1.216 ± 0.015
0.822CysThr: 0.822 ± 0.012
0.913CysVal: 0.913 ± 0.011
0.234CysTrp: 0.234 ± 0.006
0.344CysTyr: 0.344 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
4.9AspAla: 4.9 ± 0.023
0.73AspCys: 0.73 ± 0.011
4.438AspAsp: 4.438 ± 0.038
4.677AspGlu: 4.677 ± 0.034
2.437AspPhe: 2.437 ± 0.02
4.119AspGly: 4.119 ± 0.025
1.137AspHis: 1.137 ± 0.013
3.138AspIle: 3.138 ± 0.022
2.197AspLys: 2.197 ± 0.019
5.048AspLeu: 5.048 ± 0.028
1.242AspMet: 1.242 ± 0.014
1.809AspAsn: 1.809 ± 0.016
2.981AspPro: 2.981 ± 0.021
1.427AspGln: 1.427 ± 0.014
2.886AspArg: 2.886 ± 0.023
4.36AspSer: 4.36 ± 0.03
2.744AspThr: 2.744 ± 0.021
4.28AspVal: 4.28 ± 0.028
0.817AspTrp: 0.817 ± 0.01
1.388AspTyr: 1.388 ± 0.015
0.0AspXaa: 0.0 ± 0.0
Glu
4.593GluAla: 4.593 ± 0.03
0.745GluCys: 0.745 ± 0.011
4.368GluAsp: 4.368 ± 0.03
5.396GluGlu: 5.396 ± 0.044
2.143GluPhe: 2.143 ± 0.018
3.829GluGly: 3.829 ± 0.03
1.456GluHis: 1.456 ± 0.017
3.13GluIle: 3.13 ± 0.022
3.426GluLys: 3.426 ± 0.026
5.502GluLeu: 5.502 ± 0.031
1.499GluMet: 1.499 ± 0.015
2.246GluAsn: 2.246 ± 0.019
2.449GluPro: 2.449 ± 0.021
2.011GluGln: 2.011 ± 0.02
4.2GluArg: 4.2 ± 0.028
4.443GluSer: 4.443 ± 0.028
3.18GluThr: 3.18 ± 0.024
3.782GluVal: 3.782 ± 0.025
0.883GluTrp: 0.883 ± 0.011
1.535GluTyr: 1.535 ± 0.015
0.0GluXaa: 0.0 ± 0.0
Phe
3.36PheAla: 3.36 ± 0.023
0.65PheCys: 0.65 ± 0.01
2.568PheAsp: 2.568 ± 0.02
2.494PheGlu: 2.494 ± 0.022
1.828PhePhe: 1.828 ± 0.017
2.804PheGly: 2.804 ± 0.026
0.982PheHis: 0.982 ± 0.013
2.081PheIle: 2.081 ± 0.019
1.754PheLys: 1.754 ± 0.016
3.905PheLeu: 3.905 ± 0.024
0.849PheMet: 0.849 ± 0.011
1.538PheAsn: 1.538 ± 0.017
2.241PhePro: 2.241 ± 0.021
1.335PheGln: 1.335 ± 0.014
2.327PheArg: 2.327 ± 0.018
3.59PheSer: 3.59 ± 0.026
2.258PheThr: 2.258 ± 0.018
2.921PheVal: 2.921 ± 0.021
0.608PheTrp: 0.608 ± 0.01
1.111PheTyr: 1.111 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
4.671GlyAla: 4.671 ± 0.031
0.907GlyCys: 0.907 ± 0.013
3.438GlyAsp: 3.438 ± 0.022
3.545GlyGlu: 3.545 ± 0.026
2.589GlyPhe: 2.589 ± 0.022
5.075GlyGly: 5.075 ± 0.046
1.542GlyHis: 1.542 ± 0.018
3.171GlyIle: 3.171 ± 0.022
3.236GlyLys: 3.236 ± 0.022
5.322GlyLeu: 5.322 ± 0.029
1.466GlyMet: 1.466 ± 0.018
2.38GlyAsn: 2.38 ± 0.021
2.876GlyPro: 2.876 ± 0.024
2.05GlyGln: 2.05 ± 0.018
3.982GlyArg: 3.982 ± 0.027
5.601GlySer: 5.601 ± 0.035
3.649GlyThr: 3.649 ± 0.023
4.158GlyVal: 4.158 ± 0.025
0.951GlyTrp: 0.951 ± 0.013
1.699GlyTyr: 1.699 ± 0.017
0.0GlyXaa: 0.0 ± 0.0
His
1.873HisAla: 1.873 ± 0.018
0.38HisCys: 0.38 ± 0.009
1.323HisAsp: 1.323 ± 0.016
1.302HisGlu: 1.302 ± 0.016
1.121HisPhe: 1.121 ± 0.013
1.524HisGly: 1.524 ± 0.017
0.814HisHis: 0.814 ± 0.014
1.314HisIle: 1.314 ± 0.014
0.909HisLys: 0.909 ± 0.013
2.587HisLeu: 2.587 ± 0.021
0.444HisMet: 0.444 ± 0.009
0.773HisAsn: 0.773 ± 0.01
1.707HisPro: 1.707 ± 0.018
0.829HisGln: 0.829 ± 0.013
1.623HisArg: 1.623 ± 0.016
2.121HisSer: 2.121 ± 0.018
1.239HisThr: 1.239 ± 0.013
1.546HisVal: 1.546 ± 0.014
0.357HisTrp: 0.357 ± 0.007
0.66HisTyr: 0.66 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.175IleAla: 4.175 ± 0.026
0.853IleCys: 0.853 ± 0.012
2.85IleAsp: 2.85 ± 0.018
2.851IleGlu: 2.851 ± 0.022
2.23IlePhe: 2.23 ± 0.019
2.969IleGly: 2.969 ± 0.021
1.271IleHis: 1.271 ± 0.013
2.566IleIle: 2.566 ± 0.022
2.053IleLys: 2.053 ± 0.016
4.909IleLeu: 4.909 ± 0.029
0.998IleMet: 0.998 ± 0.012
1.693IleAsn: 1.693 ± 0.019
3.176IlePro: 3.176 ± 0.024
1.783IleGln: 1.783 ± 0.018
3.018IleArg: 3.018 ± 0.021
4.382IleSer: 4.382 ± 0.028
2.664IleThr: 2.664 ± 0.021
3.383IleVal: 3.383 ± 0.026
0.752IleTrp: 0.752 ± 0.012
1.328IleTyr: 1.328 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
3.971LysAla: 3.971 ± 0.03
0.598LysCys: 0.598 ± 0.01
2.756LysAsp: 2.756 ± 0.022
3.397LysGlu: 3.397 ± 0.031
1.688LysPhe: 1.688 ± 0.017
2.89LysGly: 2.89 ± 0.02
1.162LysHis: 1.162 ± 0.015
2.224LysIle: 2.224 ± 0.017
3.127LysLys: 3.127 ± 0.033
4.334LysLeu: 4.334 ± 0.029
1.007LysMet: 1.007 ± 0.011
1.69LysAsn: 1.69 ± 0.016
2.42LysPro: 2.42 ± 0.022
1.631LysGln: 1.631 ± 0.015
3.517LysArg: 3.517 ± 0.025
3.726LysSer: 3.726 ± 0.024
2.663LysThr: 2.663 ± 0.02
2.697LysVal: 2.697 ± 0.022
0.632LysTrp: 0.632 ± 0.009
1.328LysTyr: 1.328 ± 0.013
0.0LysXaa: 0.0 ± 0.0
Leu
7.7LeuAla: 7.7 ± 0.037
1.433LeuCys: 1.433 ± 0.016
5.314LeuAsp: 5.314 ± 0.03
5.889LeuGlu: 5.889 ± 0.029
3.684LeuPhe: 3.684 ± 0.027
5.303LeuGly: 5.303 ± 0.03
2.564LeuHis: 2.564 ± 0.02
3.908LeuIle: 3.908 ± 0.026
4.591LeuLys: 4.591 ± 0.029
8.94LeuLeu: 8.94 ± 0.058
1.72LeuMet: 1.72 ± 0.017
3.309LeuAsn: 3.309 ± 0.023
6.04LeuPro: 6.04 ± 0.033
3.764LeuGln: 3.764 ± 0.024
6.594LeuArg: 6.594 ± 0.037
8.636LeuSer: 8.636 ± 0.045
5.055LeuThr: 5.055 ± 0.032
5.749LeuVal: 5.749 ± 0.036
1.241LeuTrp: 1.241 ± 0.013
2.389LeuTyr: 2.389 ± 0.024
0.0LeuXaa: 0.0 ± 0.0
Met
1.771MetAla: 1.771 ± 0.016
0.277MetCys: 0.277 ± 0.007
1.319MetAsp: 1.319 ± 0.013
1.264MetGlu: 1.264 ± 0.015
0.815MetPhe: 0.815 ± 0.012
1.249MetGly: 1.249 ± 0.015
0.561MetHis: 0.561 ± 0.01
0.935MetIle: 0.935 ± 0.012
1.147MetLys: 1.147 ± 0.014
1.903MetLeu: 1.903 ± 0.015
0.522MetMet: 0.522 ± 0.008
0.858MetAsn: 0.858 ± 0.012
1.275MetPro: 1.275 ± 0.017
0.859MetGln: 0.859 ± 0.011
1.34MetArg: 1.34 ± 0.013
2.034MetSer: 2.034 ± 0.017
1.273MetThr: 1.273 ± 0.014
1.151MetVal: 1.151 ± 0.014
0.258MetTrp: 0.258 ± 0.006
0.512MetTyr: 0.512 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.319AsnAla: 3.319 ± 0.024
0.495AsnCys: 0.495 ± 0.009
2.047AsnAsp: 2.047 ± 0.017
2.087AsnGlu: 2.087 ± 0.019
1.573AsnPhe: 1.573 ± 0.016
2.726AsnGly: 2.726 ± 0.024
0.78AsnHis: 0.78 ± 0.009
2.097AsnIle: 2.097 ± 0.017
1.379AsnLys: 1.379 ± 0.015
3.554AsnLeu: 3.554 ± 0.025
0.798AsnMet: 0.798 ± 0.011
1.402AsnAsn: 1.402 ± 0.015
2.265AsnPro: 2.265 ± 0.021
1.108AsnGln: 1.108 ± 0.014
1.9AsnArg: 1.9 ± 0.018
3.075AsnSer: 3.075 ± 0.023
2.064AsnThr: 2.064 ± 0.018
2.681AsnVal: 2.681 ± 0.019
0.496AsnTrp: 0.496 ± 0.009
0.942AsnTyr: 0.942 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
4.382ProAla: 4.382 ± 0.029
0.585ProCys: 0.585 ± 0.012
2.939ProAsp: 2.939 ± 0.02
3.368ProGlu: 3.368 ± 0.023
2.358ProPhe: 2.358 ± 0.019
3.375ProGly: 3.375 ± 0.029
1.395ProHis: 1.395 ± 0.017
2.625ProIle: 2.625 ± 0.019
2.408ProLys: 2.408 ± 0.021
5.04ProLeu: 5.04 ± 0.032
1.075ProMet: 1.075 ± 0.013
2.282ProAsn: 2.282 ± 0.019
5.412ProPro: 5.412 ± 0.067
2.098ProGln: 2.098 ± 0.02
3.305ProArg: 3.305 ± 0.027
6.994ProSer: 6.994 ± 0.049
3.82ProThr: 3.82 ± 0.03
3.338ProVal: 3.338 ± 0.026
0.613ProTrp: 0.613 ± 0.01
1.445ProTyr: 1.445 ± 0.015
0.0ProXaa: 0.0 ± 0.0
Gln
2.908GlnAla: 2.908 ± 0.021
0.471GlnCys: 0.471 ± 0.008
1.732GlnAsp: 1.732 ± 0.016
2.007GlnGlu: 2.007 ± 0.02
1.317GlnPhe: 1.317 ± 0.015
1.906GlnGly: 1.906 ± 0.017
1.003GlnHis: 1.003 ± 0.014
1.777GlnIle: 1.777 ± 0.015
1.632GlnLys: 1.632 ± 0.015
3.234GlnLeu: 3.234 ± 0.023
0.821GlnMet: 0.821 ± 0.012
1.438GlnAsn: 1.438 ± 0.013
1.922GlnPro: 1.922 ± 0.019
1.869GlnGln: 1.869 ± 0.037
2.428GlnArg: 2.428 ± 0.022
2.987GlnSer: 2.987 ± 0.02
2.158GlnThr: 2.158 ± 0.019
2.001GlnVal: 2.001 ± 0.016
0.455GlnTrp: 0.455 ± 0.009
0.945GlnTyr: 0.945 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
4.76ArgAla: 4.76 ± 0.034
0.985ArgCys: 0.985 ± 0.012
3.353ArgAsp: 3.353 ± 0.025
3.84ArgGlu: 3.84 ± 0.031
2.461ArgPhe: 2.461 ± 0.017
3.562ArgGly: 3.562 ± 0.031
1.608ArgHis: 1.608 ± 0.016
3.235ArgIle: 3.235 ± 0.022
3.552ArgLys: 3.552 ± 0.023
5.828ArgLeu: 5.828 ± 0.034
1.418ArgMet: 1.418 ± 0.014
2.406ArgAsn: 2.406 ± 0.02
3.323ArgPro: 3.323 ± 0.025
2.239ArgGln: 2.239 ± 0.022
5.758ArgArg: 5.758 ± 0.036
5.615ArgSer: 5.615 ± 0.036
3.691ArgThr: 3.691 ± 0.024
3.708ArgVal: 3.708 ± 0.023
1.019ArgTrp: 1.019 ± 0.013
1.647ArgTyr: 1.647 ± 0.015
0.0ArgXaa: 0.0 ± 0.0
Ser
6.74SerAla: 6.74 ± 0.04
1.185SerCys: 1.185 ± 0.014
4.685SerAsp: 4.685 ± 0.032
4.547SerGlu: 4.547 ± 0.029
3.83SerPhe: 3.83 ± 0.026
5.559SerGly: 5.559 ± 0.033
1.998SerHis: 1.998 ± 0.019
4.488SerIle: 4.488 ± 0.026
4.168SerLys: 4.168 ± 0.029
8.651SerLeu: 8.651 ± 0.039
1.913SerMet: 1.913 ± 0.017
3.498SerAsn: 3.498 ± 0.023
5.916SerPro: 5.916 ± 0.046
3.115SerGln: 3.115 ± 0.024
5.712SerArg: 5.712 ± 0.034
11.6SerSer: 11.6 ± 0.09
6.313SerThr: 6.313 ± 0.048
5.315SerVal: 5.315 ± 0.029
1.12SerTrp: 1.12 ± 0.014
2.108SerTyr: 2.108 ± 0.02
0.0SerXaa: 0.0 ± 0.0
Thr
4.403ThrAla: 4.403 ± 0.026
0.823ThrCys: 0.823 ± 0.012
2.682ThrAsp: 2.682 ± 0.023
2.764ThrGlu: 2.764 ± 0.021
2.64ThrPhe: 2.64 ± 0.023
3.428ThrGly: 3.428 ± 0.025
1.332ThrHis: 1.332 ± 0.014
3.133ThrIle: 3.133 ± 0.022
2.486ThrLys: 2.486 ± 0.02
5.645ThrLeu: 5.645 ± 0.032
1.181ThrMet: 1.181 ± 0.013
2.166ThrAsn: 2.166 ± 0.018
4.045ThrPro: 4.045 ± 0.031
1.904ThrGln: 1.904 ± 0.018
3.324ThrArg: 3.324 ± 0.025
6.094ThrSer: 6.094 ± 0.045
4.033ThrThr: 4.033 ± 0.032
3.664ThrVal: 3.664 ± 0.025
0.747ThrTrp: 0.747 ± 0.011
1.499ThrTyr: 1.499 ± 0.014
0.0ThrXaa: 0.0 ± 0.0
Val
5.063ValAla: 5.063 ± 0.032
0.972ValCys: 0.972 ± 0.013
3.978ValAsp: 3.978 ± 0.023
4.015ValGlu: 4.015 ± 0.025
2.69ValPhe: 2.69 ± 0.023
3.751ValGly: 3.751 ± 0.023
1.663ValHis: 1.663 ± 0.016
3.068ValIle: 3.068 ± 0.022
3.063ValLys: 3.063 ± 0.023
6.139ValLeu: 6.139 ± 0.028
1.285ValMet: 1.285 ± 0.014
2.287ValAsn: 2.287 ± 0.019
3.664ValPro: 3.664 ± 0.024
2.357ValGln: 2.357 ± 0.017
3.711ValArg: 3.711 ± 0.025
5.025ValSer: 5.025 ± 0.028
3.421ValThr: 3.421 ± 0.026
4.646ValVal: 4.646 ± 0.032
0.896ValTrp: 0.896 ± 0.012
1.711ValTyr: 1.711 ± 0.016
0.0ValXaa: 0.0 ± 0.0
Trp
0.964TrpAla: 0.964 ± 0.012
0.223TrpCys: 0.223 ± 0.006
0.845TrpAsp: 0.845 ± 0.013
0.784TrpGlu: 0.784 ± 0.011
0.531TrpPhe: 0.531 ± 0.009
0.746TrpGly: 0.746 ± 0.01
0.317TrpHis: 0.317 ± 0.007
0.745TrpIle: 0.745 ± 0.01
0.843TrpLys: 0.843 ± 0.011
1.223TrpLeu: 1.223 ± 0.013
0.406TrpMet: 0.406 ± 0.008
0.639TrpAsn: 0.639 ± 0.009
0.565TrpPro: 0.565 ± 0.008
0.423TrpGln: 0.423 ± 0.008
1.03TrpArg: 1.03 ± 0.014
1.138TrpSer: 1.138 ± 0.014
0.902TrpThr: 0.902 ± 0.013
0.777TrpVal: 0.777 ± 0.011
0.231TrpTrp: 0.231 ± 0.006
0.355TrpTyr: 0.355 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.097TyrAla: 2.097 ± 0.018
0.435TyrCys: 0.435 ± 0.008
1.616TyrAsp: 1.616 ± 0.016
1.507TyrGlu: 1.507 ± 0.013
1.234TyrPhe: 1.234 ± 0.013
1.738TyrGly: 1.738 ± 0.018
0.657TyrHis: 0.657 ± 0.01
1.334TyrIle: 1.334 ± 0.014
1.044TyrLys: 1.044 ± 0.014
2.55TyrLeu: 2.55 ± 0.023
0.56TyrMet: 0.56 ± 0.008
0.967TyrAsn: 0.967 ± 0.011
1.368TyrPro: 1.368 ± 0.015
0.799TyrGln: 0.799 ± 0.011
1.542TyrArg: 1.542 ± 0.016
2.051TyrSer: 2.051 ± 0.019
1.412TyrThr: 1.412 ± 0.013
1.645TyrVal: 1.645 ± 0.017
0.375TyrTrp: 0.375 ± 0.008
0.851TyrTyr: 0.851 ± 0.012
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 17051 proteins (7036197 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski