Leopards Hill virus

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Ellioviricetes; Bunyavirales; Nairoviridae; Orthonairovirus; Leopards Hill orthonairovirus

Average proteome isoelectric point is 6.62

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A0B6VMT2|A0A0B6VMT2_9VIRU Glycoprotein G2 OS=Leopards Hill virus OX=1381104 GN=GP PE=4 SV=1
MM1 pKa = 7.75SEE3 pKa = 5.54LNFKK7 pKa = 10.19DD8 pKa = 5.12LNGLNNWFEE17 pKa = 4.22EE18 pKa = 4.45FKK20 pKa = 10.86KK21 pKa = 10.61DD22 pKa = 3.66VPIYY26 pKa = 10.16TSGANSACLSSGLVDD41 pKa = 4.33LSQFKK46 pKa = 11.23LEE48 pKa = 4.26IDD50 pKa = 3.68AQSSEE55 pKa = 4.28SAKK58 pKa = 9.75NAVYY62 pKa = 10.4GRR64 pKa = 11.84AVIAATRR71 pKa = 11.84NLAPIYY77 pKa = 8.7EE78 pKa = 4.69CAWTSCEE85 pKa = 4.32GIFEE89 pKa = 5.2RR90 pKa = 11.84SMSWFNDD97 pKa = 3.16NADD100 pKa = 3.59KK101 pKa = 11.3PEE103 pKa = 3.99FKK105 pKa = 10.26VWHH108 pKa = 6.95DD109 pKa = 3.85KK110 pKa = 11.64YY111 pKa = 11.71NDD113 pKa = 3.62LKK115 pKa = 11.51SNLPEE120 pKa = 3.93VEE122 pKa = 4.63QILAYY127 pKa = 9.3QNCSSLWRR135 pKa = 11.84KK136 pKa = 10.24DD137 pKa = 2.69IGYY140 pKa = 9.09EE141 pKa = 3.84INQNTSTLKK150 pKa = 10.08GDD152 pKa = 3.19IVEE155 pKa = 4.39EE156 pKa = 4.21YY157 pKa = 10.57GVNRR161 pKa = 11.84NIVGTVKK168 pKa = 10.74NMLVDD173 pKa = 3.66MVNKK177 pKa = 10.01RR178 pKa = 11.84KK179 pKa = 9.86KK180 pKa = 9.56RR181 pKa = 11.84LGGVVITGAGTSEE194 pKa = 4.55DD195 pKa = 4.04HH196 pKa = 6.02ITWMEE201 pKa = 3.49NWLDD205 pKa = 3.69GEE207 pKa = 4.56IEE209 pKa = 4.34SFSIPGWGSWAKK221 pKa = 10.38QNSKK225 pKa = 8.16GTRR228 pKa = 11.84LAGTAIANIMQKK240 pKa = 10.23KK241 pKa = 10.53DD242 pKa = 2.96SDD244 pKa = 3.94ALEE247 pKa = 4.15KK248 pKa = 10.91AKK250 pKa = 10.91EE251 pKa = 4.13KK252 pKa = 10.66LEE254 pKa = 4.05KK255 pKa = 9.58MKK257 pKa = 9.63KK258 pKa = 7.73TADD261 pKa = 3.67DD262 pKa = 4.01PASLEE267 pKa = 4.2SEE269 pKa = 4.28GMSEE273 pKa = 4.22DD274 pKa = 3.68AAKK277 pKa = 10.59KK278 pKa = 8.56MCQEE282 pKa = 3.96VEE284 pKa = 3.9ASIEE288 pKa = 4.01EE289 pKa = 4.33AEE291 pKa = 4.41VLLGTNVAQGEE302 pKa = 4.61SKK304 pKa = 10.71YY305 pKa = 9.53QQQAAAMDD313 pKa = 4.24VPFSAHH319 pKa = 3.7YY320 pKa = 8.1WAWRR324 pKa = 11.84CKK326 pKa = 9.9VNEE329 pKa = 4.01NSFPALSQWLFEE341 pKa = 4.58LGQRR345 pKa = 11.84PIGAAKK351 pKa = 9.72INTMLGEE358 pKa = 4.77LPFIWARR365 pKa = 11.84NIRR368 pKa = 11.84GSFASSNFNGNKK380 pKa = 9.33IYY382 pKa = 8.85MHH384 pKa = 6.78PAVLTAGRR392 pKa = 11.84LSDD395 pKa = 3.39MAACFGAFPVANPQRR410 pKa = 11.84AAEE413 pKa = 4.3GTGNTRR419 pKa = 11.84YY420 pKa = 10.31LLNLKK425 pKa = 10.41RR426 pKa = 11.84EE427 pKa = 4.03GDD429 pKa = 3.88NPCASMVTSLFDD441 pKa = 3.3VFSAGFKK448 pKa = 9.06YY449 pKa = 10.58QDD451 pKa = 3.41MDD453 pKa = 3.67IVPPEE458 pKa = 4.16HH459 pKa = 6.65MLHH462 pKa = 6.36QSFLGKK468 pKa = 9.1TSPFQTANKK477 pKa = 9.66IKK479 pKa = 10.79GSFTKK484 pKa = 10.25INVVAAPNKK493 pKa = 5.83PTPYY497 pKa = 10.39VFTPASAKK505 pKa = 10.08KK506 pKa = 9.97IKK508 pKa = 9.73EE509 pKa = 3.89KK510 pKa = 10.43KK511 pKa = 9.15ARR513 pKa = 11.84KK514 pKa = 8.96

Molecular weight:
57.09 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A0B6VMT2|A0A0B6VMT2_9VIRU Glycoprotein G2 OS=Leopards Hill virus OX=1381104 GN=GP PE=4 SV=1
MM1 pKa = 6.81EE2 pKa = 5.24TYY4 pKa = 10.29HH5 pKa = 6.68GSRR8 pKa = 11.84YY9 pKa = 7.43TATSCLFFVIMLVVAITADD28 pKa = 3.58NNVTEE33 pKa = 4.43TTTAEE38 pKa = 4.36VVSNTTGSTEE48 pKa = 4.16GDD50 pKa = 3.67TTSKK54 pKa = 11.15GMDD57 pKa = 3.27TTQIPQINQTSATTRR72 pKa = 11.84SNNITTKK79 pKa = 9.21TSRR82 pKa = 11.84SEE84 pKa = 4.18SGVDD88 pKa = 3.64PSATQPLLVSSQASGTIGQQRR109 pKa = 11.84GLSPTPDD116 pKa = 3.28PGARR120 pKa = 11.84IRR122 pKa = 11.84VKK124 pKa = 10.11GGKK127 pKa = 8.98RR128 pKa = 11.84RR129 pKa = 11.84AEE131 pKa = 3.81RR132 pKa = 11.84LTARR136 pKa = 11.84LDD138 pKa = 3.6VNGNRR143 pKa = 11.84VVLKK147 pKa = 10.78RR148 pKa = 11.84EE149 pKa = 3.59ISGNLQLAKK158 pKa = 10.22EE159 pKa = 4.05QLEE162 pKa = 4.18EE163 pKa = 3.97AVLNMEE169 pKa = 4.75IDD171 pKa = 3.86SLDD174 pKa = 3.73LEE176 pKa = 4.35QLEE179 pKa = 4.57EE180 pKa = 3.97EE181 pKa = 4.29SPYY184 pKa = 11.09RR185 pKa = 11.84SMQRR189 pKa = 11.84TRR191 pKa = 11.84LMLPKK196 pKa = 10.3LEE198 pKa = 4.03SFAYY202 pKa = 10.47NEE204 pKa = 4.07EE205 pKa = 4.03QEE207 pKa = 4.25EE208 pKa = 4.36DD209 pKa = 3.92VMVTGKK215 pKa = 10.62LSRR218 pKa = 11.84FTRR221 pKa = 11.84FEE223 pKa = 4.43RR224 pKa = 11.84INIDD228 pKa = 3.15KK229 pKa = 10.84LEE231 pKa = 4.79SITVFQNLTNRR242 pKa = 11.84SVLTLCTYY250 pKa = 10.47FGHH253 pKa = 6.63YY254 pKa = 9.23YY255 pKa = 10.93NKK257 pKa = 8.65TLKK260 pKa = 9.1GTTVSIHH267 pKa = 6.1HH268 pKa = 6.64KK269 pKa = 10.52CDD271 pKa = 3.71IEE273 pKa = 4.48TQCKK277 pKa = 10.05GLTEE281 pKa = 4.23HH282 pKa = 6.75VSIDD286 pKa = 4.48RR287 pKa = 11.84ITNYY291 pKa = 11.17DD292 pKa = 3.6NIKK295 pKa = 9.9IINIMEE301 pKa = 4.29LPVIIIAYY309 pKa = 5.52FTRR312 pKa = 11.84HH313 pKa = 6.03FGFTYY318 pKa = 10.11KK319 pKa = 10.71NLVIHH324 pKa = 6.14EE325 pKa = 4.31QIEE328 pKa = 4.41NCLFFYY334 pKa = 9.82PQNPVACMEE343 pKa = 4.41NNWGGRR349 pKa = 11.84SHH351 pKa = 7.13PVVHH355 pKa = 6.57LVIEE359 pKa = 4.62RR360 pKa = 11.84KK361 pKa = 9.12YY362 pKa = 11.01LKK364 pKa = 10.07ADD366 pKa = 3.55SSITLCGLKK375 pKa = 10.18KK376 pKa = 10.78GNPTSLKK383 pKa = 9.01GTWFAEE389 pKa = 4.3KK390 pKa = 10.06TKK392 pKa = 10.04VTIDD396 pKa = 3.12LGEE399 pKa = 4.21PQTAGRR405 pKa = 11.84RR406 pKa = 11.84KK407 pKa = 9.71LLAIEE412 pKa = 4.09RR413 pKa = 11.84RR414 pKa = 11.84RR415 pKa = 11.84RR416 pKa = 11.84LPGRR420 pKa = 11.84EE421 pKa = 4.51DD422 pKa = 3.21IRR424 pKa = 11.84CHH426 pKa = 6.73SGSHH430 pKa = 5.66LVKK433 pKa = 9.49IDD435 pKa = 3.31KK436 pKa = 9.64YY437 pKa = 11.14APTNEE442 pKa = 4.08FQSFPNAKK450 pKa = 9.55IGFCNDD456 pKa = 3.44SIITHH461 pKa = 6.8LPLGQEE467 pKa = 4.5FGCYY471 pKa = 8.44RR472 pKa = 11.84VGSVKK477 pKa = 9.1THH479 pKa = 5.11VQCKK483 pKa = 8.49PYY485 pKa = 10.28HH486 pKa = 5.96HH487 pKa = 7.11AFDD490 pKa = 4.58GEE492 pKa = 4.51KK493 pKa = 8.84TCNVSSDD500 pKa = 3.37GDD502 pKa = 3.78CRR504 pKa = 11.84EE505 pKa = 4.39GEE507 pKa = 3.82LCAAVKK513 pKa = 10.82LNGQGIITARR523 pKa = 11.84THH525 pKa = 5.76LGEE528 pKa = 4.27VQVKK532 pKa = 9.81HH533 pKa = 6.47CLEE536 pKa = 4.08EE537 pKa = 4.31CQFSFTRR544 pKa = 11.84VNDD547 pKa = 3.69LEE549 pKa = 4.63VSFTCPDD556 pKa = 3.15GQQRR560 pKa = 11.84RR561 pKa = 11.84LHH563 pKa = 6.29SNAVDD568 pKa = 3.88TNCPFQNKK576 pKa = 9.62LGVYY580 pKa = 9.9ALYY583 pKa = 10.49VCRR586 pKa = 11.84ATHH589 pKa = 6.56RR590 pKa = 11.84PLVLYY595 pKa = 7.41TTFIWFVVGTIVLATSLQMISVTVKK620 pKa = 9.1LYY622 pKa = 10.79CYY624 pKa = 10.31LVVLAKK630 pKa = 10.47RR631 pKa = 11.84KK632 pKa = 9.88LDD634 pKa = 3.51TGKK637 pKa = 10.69GVCTDD642 pKa = 3.48CGEE645 pKa = 4.61SVLSTEE651 pKa = 3.72EE652 pKa = 3.98WQRR655 pKa = 11.84HH656 pKa = 3.89QACKK660 pKa = 10.13KK661 pKa = 9.93GKK663 pKa = 9.93CPYY666 pKa = 10.0CGVKK670 pKa = 10.7GSGNDD675 pKa = 3.52VQKK678 pKa = 11.06HH679 pKa = 5.39VINCLQRR686 pKa = 11.84EE687 pKa = 4.44TVLEE691 pKa = 4.16HH692 pKa = 7.1DD693 pKa = 4.94LNVLTIRR700 pKa = 11.84RR701 pKa = 11.84TPRR704 pKa = 11.84YY705 pKa = 9.55ALRR708 pKa = 11.84LGCFLNALQGRR719 pKa = 11.84PIRR722 pKa = 11.84LIWLVVLLLLFVFLIKK738 pKa = 10.06PVRR741 pKa = 11.84SLEE744 pKa = 4.35TNDD747 pKa = 3.17QTEE750 pKa = 4.4GLWEE754 pKa = 3.97EE755 pKa = 4.77GIEE758 pKa = 4.05EE759 pKa = 4.28VEE761 pKa = 4.39KK762 pKa = 10.98CGKK765 pKa = 9.29GCWYY769 pKa = 10.25NQDD772 pKa = 2.76VCTCDD777 pKa = 3.53KK778 pKa = 10.99EE779 pKa = 5.0EE780 pKa = 4.29PLHH783 pKa = 5.4TSRR786 pKa = 11.84HH787 pKa = 5.15ILSVPAKK794 pKa = 10.35DD795 pKa = 3.75DD796 pKa = 3.8TEE798 pKa = 4.23KK799 pKa = 10.62ATSKK803 pKa = 10.56DD804 pKa = 3.54RR805 pKa = 11.84QGKK808 pKa = 9.44KK809 pKa = 8.0VMRR812 pKa = 11.84SLDD815 pKa = 3.51VEE817 pKa = 4.55APWGTLHH824 pKa = 7.41IPEE827 pKa = 4.6TFSPAGSVKK836 pKa = 10.22HH837 pKa = 6.57ISLSWEE843 pKa = 3.76SSRR846 pKa = 11.84VVGKK850 pKa = 10.33RR851 pKa = 11.84VILSGKK857 pKa = 8.1STAILKK863 pKa = 9.37LNPKK867 pKa = 9.24TSTSWEE873 pKa = 4.19MTSPDD878 pKa = 3.59ANEE881 pKa = 4.15KK882 pKa = 10.61KK883 pKa = 10.38ILTLSILDD891 pKa = 3.48YY892 pKa = 9.52TQIYY896 pKa = 9.59SSRR899 pKa = 11.84FEE901 pKa = 4.2YY902 pKa = 9.88LTGDD906 pKa = 3.48RR907 pKa = 11.84KK908 pKa = 9.28VTTWSEE914 pKa = 4.65GSCTGPCPKK923 pKa = 10.45DD924 pKa = 3.65CGCNDD929 pKa = 4.06PSCHH933 pKa = 5.82TKK935 pKa = 9.79QWLNTRR941 pKa = 11.84NWRR944 pKa = 11.84CNPTWCWGIGTGCSCCSAKK963 pKa = 10.55VVDD966 pKa = 5.93LYY968 pKa = 11.7KK969 pKa = 10.87NWLVSIWQIEE979 pKa = 4.35HH980 pKa = 6.57LRR982 pKa = 11.84TPVVACLEE990 pKa = 4.12FDD992 pKa = 3.63HH993 pKa = 6.81EE994 pKa = 4.36NRR996 pKa = 11.84VCDD999 pKa = 3.71VVEE1002 pKa = 4.37AGIEE1006 pKa = 4.06IQLGPVTVAFSDD1018 pKa = 3.62PFGEE1022 pKa = 4.8QKK1024 pKa = 10.41ILPQRR1029 pKa = 11.84IAVYY1033 pKa = 9.91HH1034 pKa = 6.14KK1035 pKa = 9.8RR1036 pKa = 11.84DD1037 pKa = 3.27VDD1039 pKa = 3.8HH1040 pKa = 6.68EE1041 pKa = 4.41HH1042 pKa = 6.97VDD1044 pKa = 3.61LLHH1047 pKa = 5.83NHH1049 pKa = 7.44GIGGAEE1055 pKa = 4.37QYY1057 pKa = 10.68CKK1059 pKa = 10.55LQSCTHH1065 pKa = 5.87GTAGDD1070 pKa = 3.8YY1071 pKa = 10.87QIINPDD1077 pKa = 3.41ALVFDD1082 pKa = 6.57DD1083 pKa = 4.28ITSMNYY1089 pKa = 9.2FKK1091 pKa = 11.17KK1092 pKa = 10.57LDD1094 pKa = 3.78VYY1096 pKa = 11.36NKK1098 pKa = 10.14LWMSWEE1104 pKa = 4.09GVNLGYY1110 pKa = 10.69YY1111 pKa = 9.61CNPGDD1116 pKa = 3.74WTTCTAEE1123 pKa = 4.19NIVVRR1128 pKa = 11.84NSEE1131 pKa = 4.01AFSNRR1136 pKa = 11.84NNLEE1140 pKa = 3.75RR1141 pKa = 11.84NYY1143 pKa = 10.41SVSHH1147 pKa = 6.7FFHH1150 pKa = 7.04SSRR1153 pKa = 11.84VYY1155 pKa = 10.64GSGKK1159 pKa = 10.02SLVMDD1164 pKa = 4.22LKK1166 pKa = 10.99GRR1168 pKa = 11.84PIQSGGNINVYY1179 pKa = 8.67VTVNNLEE1186 pKa = 4.29LNSKK1190 pKa = 10.11KK1191 pKa = 10.75VVITGLKK1198 pKa = 9.57VNLRR1202 pKa = 11.84ACTGCFGCNLGAEE1215 pKa = 4.58CQISLSLTEE1224 pKa = 4.29PDD1226 pKa = 4.02EE1227 pKa = 4.22FHH1229 pKa = 6.89LHH1231 pKa = 6.06LKK1233 pKa = 10.35SVTPGVTVPDD1243 pKa = 3.5TSFLVTSSEE1252 pKa = 3.59EE1253 pKa = 3.56KK1254 pKa = 9.77MFNIRR1259 pKa = 11.84VFSILKK1265 pKa = 9.92DD1266 pKa = 3.45VNFCIEE1272 pKa = 4.03VLEE1275 pKa = 4.73SKK1277 pKa = 10.31HH1278 pKa = 7.21CPEE1281 pKa = 5.16CDD1283 pKa = 3.27KK1284 pKa = 11.41KK1285 pKa = 10.97DD1286 pKa = 3.81LQSCLQLTFEE1296 pKa = 4.71DD1297 pKa = 4.38PKK1299 pKa = 11.0PVLLEE1304 pKa = 3.86HH1305 pKa = 7.01RR1306 pKa = 11.84SVLFSKK1312 pKa = 10.84SNQTCGDD1319 pKa = 3.61STISCWSSSAGILFKK1334 pKa = 11.2GIGNFLSTHH1343 pKa = 6.52FGSIFRR1349 pKa = 11.84GILLSVLPILLIVGLIFFSPQIISLMRR1376 pKa = 11.84LCKK1379 pKa = 9.99RR1380 pKa = 11.84GRR1382 pKa = 11.84SVVGFRR1388 pKa = 11.84KK1389 pKa = 9.92RR1390 pKa = 11.84FYY1392 pKa = 11.13KK1393 pKa = 10.55PLTDD1397 pKa = 3.9GADD1400 pKa = 3.1MGLSAEE1406 pKa = 4.39EE1407 pKa = 4.24KK1408 pKa = 10.82AFLTGIFGKK1417 pKa = 10.53KK1418 pKa = 9.5KK1419 pKa = 9.51EE1420 pKa = 4.07

Molecular weight:
159.38 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

5901

514

3967

1967.0

222.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.118 ± 1.254

2.61 ± 0.596

5.05 ± 0.309

7.202 ± 0.367

4.203 ± 0.135

5.287 ± 0.895

2.135 ± 0.359

5.965 ± 0.262

7.541 ± 0.519

10.185 ± 1.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.339 ± 0.433

5.118 ± 0.479

3.474 ± 0.224

3.474 ± 0.024

4.931 ± 0.408

8.863 ± 0.678

5.626 ± 0.878

6.779 ± 0.44

1.288 ± 0.364

2.813 ± 0.109

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski