Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1)

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes; Amarillovirales; Flaviviridae; Flavivirus; Dengue virus; Dengue virus 1

Average proteome isoelectric point is 7.34

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|P17763|POLG_DEN1W Genome polyprotein OS=Dengue virus type 1 (strain Nauru/West Pac/1974) OX=11059 PE=1 SV=2
MM1 pKa = 7.38NNQRR5 pKa = 11.84KK6 pKa = 7.83KK7 pKa = 8.92TGRR10 pKa = 11.84PSFNMLKK17 pKa = 10.18RR18 pKa = 11.84ARR20 pKa = 11.84NRR22 pKa = 11.84VSTVSQLAKK31 pKa = 10.25RR32 pKa = 11.84FSKK35 pKa = 10.85GLLSGQGPMKK45 pKa = 10.59LVMAFIAFLRR55 pKa = 11.84FLAIPPTAGILARR68 pKa = 11.84WGSFKK73 pKa = 11.04KK74 pKa = 10.57NGAIKK79 pKa = 10.3VLRR82 pKa = 11.84GFKK85 pKa = 10.5KK86 pKa = 10.41EE87 pKa = 3.64ISNMLNIMNRR97 pKa = 11.84RR98 pKa = 11.84KK99 pKa = 10.18RR100 pKa = 11.84SVTMLLMLLPTALAFHH116 pKa = 6.92LTTRR120 pKa = 11.84GGEE123 pKa = 3.66PHH125 pKa = 6.74MIVSKK130 pKa = 8.28QEE132 pKa = 3.76RR133 pKa = 11.84GKK135 pKa = 10.85SLLFKK140 pKa = 10.42TSAGVNMCTLIAMDD154 pKa = 5.01LGEE157 pKa = 4.53LCEE160 pKa = 4.23DD161 pKa = 3.5TMTYY165 pKa = 9.35KK166 pKa = 10.65CPRR169 pKa = 11.84ITEE172 pKa = 4.26TEE174 pKa = 4.12PDD176 pKa = 6.07DD177 pKa = 4.27VDD179 pKa = 3.64CWCNATEE186 pKa = 4.01TWVTYY191 pKa = 7.35GTCSQTGEE199 pKa = 3.75HH200 pKa = 6.46RR201 pKa = 11.84RR202 pKa = 11.84DD203 pKa = 3.38KK204 pKa = 10.95RR205 pKa = 11.84SVALAPHH212 pKa = 6.3VGLGLEE218 pKa = 4.45TRR220 pKa = 11.84TEE222 pKa = 3.81TWMSSEE228 pKa = 4.24GAWKK232 pKa = 10.05QIQKK236 pKa = 9.99VEE238 pKa = 4.0TWALRR243 pKa = 11.84HH244 pKa = 6.23PGFTVIALFLAHH256 pKa = 7.64AIGTSITQKK265 pKa = 10.92GIIFILLMLVTPSMAMRR282 pKa = 11.84CVGIGNRR289 pKa = 11.84DD290 pKa = 3.44FVEE293 pKa = 4.55GLSGATWVDD302 pKa = 3.42VVLEE306 pKa = 4.39HH307 pKa = 6.6GSCVTTMAKK316 pKa = 10.26DD317 pKa = 3.36KK318 pKa = 8.44PTLDD322 pKa = 3.19IEE324 pKa = 4.32LLKK327 pKa = 10.49TEE329 pKa = 4.21VTNPAVLRR337 pKa = 11.84KK338 pKa = 9.89LCIEE342 pKa = 4.17AKK344 pKa = 10.1ISNTTTDD351 pKa = 3.5SRR353 pKa = 11.84CPTQGEE359 pKa = 4.1ATLVEE364 pKa = 4.24EE365 pKa = 3.99QDD367 pKa = 3.68TNFVCRR373 pKa = 11.84RR374 pKa = 11.84TFVDD378 pKa = 3.54RR379 pKa = 11.84GWGNGCGLFGKK390 pKa = 10.7GSLITCAKK398 pKa = 8.56FKK400 pKa = 10.84CVTKK404 pKa = 11.04LEE406 pKa = 4.34GKK408 pKa = 9.57IVQYY412 pKa = 11.26EE413 pKa = 3.93NLKK416 pKa = 9.73YY417 pKa = 10.19SVIVTVHH424 pKa = 6.31TGDD427 pKa = 3.11QHH429 pKa = 6.63QVGNEE434 pKa = 4.04TTEE437 pKa = 4.05HH438 pKa = 6.03GTTATITPQAPTSEE452 pKa = 4.26IQLTDD457 pKa = 3.56YY458 pKa = 11.24GALTLDD464 pKa = 3.9CSPRR468 pKa = 11.84TGLDD472 pKa = 3.3FNEE475 pKa = 4.28MVLLTMEE482 pKa = 4.33KK483 pKa = 10.38KK484 pKa = 9.7SWLVHH489 pKa = 5.22KK490 pKa = 10.27QWFLDD495 pKa = 4.68LPLPWTSGASTSQEE509 pKa = 3.26TWNRR513 pKa = 11.84QDD515 pKa = 4.38LLVTFKK521 pKa = 10.04TAHH524 pKa = 6.18AKK526 pKa = 8.85KK527 pKa = 10.34QEE529 pKa = 4.03VVVLGSQEE537 pKa = 4.23GAMHH541 pKa = 6.57TALTGATEE549 pKa = 4.19IQTSGTTTIFAGHH562 pKa = 6.79LKK564 pKa = 10.4CRR566 pKa = 11.84LKK568 pKa = 10.03MDD570 pKa = 3.68KK571 pKa = 9.94LTLKK575 pKa = 10.46GMSYY579 pKa = 10.82VMCTGSFKK587 pKa = 10.99LEE589 pKa = 3.96KK590 pKa = 10.14EE591 pKa = 4.38VAEE594 pKa = 4.43TQHH597 pKa = 5.63GTVLVQVKK605 pKa = 10.01YY606 pKa = 10.26EE607 pKa = 4.17GTDD610 pKa = 3.59APCKK614 pKa = 10.24IPFSSQDD621 pKa = 3.42EE622 pKa = 4.43KK623 pKa = 11.59GVTQNGRR630 pKa = 11.84LITANPIVTDD640 pKa = 3.34KK641 pKa = 10.59EE642 pKa = 4.19KK643 pKa = 10.61PVNIEE648 pKa = 3.65AEE650 pKa = 4.26PPFGEE655 pKa = 4.4SYY657 pKa = 10.55IVVGAGEE664 pKa = 4.29KK665 pKa = 10.22ALKK668 pKa = 10.56LSWFKK673 pKa = 10.84KK674 pKa = 9.44GSSIGKK680 pKa = 8.45MFEE683 pKa = 3.59ATARR687 pKa = 11.84GARR690 pKa = 11.84RR691 pKa = 11.84MAILGDD697 pKa = 3.83TAWDD701 pKa = 3.93FGSIGGVFTSVGKK714 pKa = 10.4LIHH717 pKa = 6.32QIFGTAYY724 pKa = 7.96GVLFSGVSWTMKK736 pKa = 9.93IGIGILLTWLGLNSRR751 pKa = 11.84STSLSMTCIAVGMVTLYY768 pKa = 10.85LGVMVQADD776 pKa = 4.31SGCVINWKK784 pKa = 10.03GRR786 pKa = 11.84EE787 pKa = 4.12LKK789 pKa = 10.31CGSGIFVTNEE799 pKa = 3.11VHH801 pKa = 6.28TWTEE805 pKa = 3.82QYY807 pKa = 10.86KK808 pKa = 9.78FQADD812 pKa = 3.64SPKK815 pKa = 10.31RR816 pKa = 11.84LSAAIGKK823 pKa = 8.88AWEE826 pKa = 4.27EE827 pKa = 4.47GVCGIRR833 pKa = 11.84SATRR837 pKa = 11.84LEE839 pKa = 4.17NIMWKK844 pKa = 10.26QISNEE849 pKa = 3.92LNHH852 pKa = 6.9ILLEE856 pKa = 4.14NDD858 pKa = 3.13MKK860 pKa = 10.51FTVVVGDD867 pKa = 3.21VSGILAQGKK876 pKa = 10.14KK877 pKa = 9.36MIRR880 pKa = 11.84PQPMEE885 pKa = 4.55HH886 pKa = 6.71KK887 pKa = 10.44YY888 pKa = 10.29SWKK891 pKa = 9.89SWGKK895 pKa = 10.54AKK897 pKa = 10.46IIGADD902 pKa = 3.48VQNTTFIIDD911 pKa = 3.81GPNTPEE917 pKa = 4.54CPDD920 pKa = 3.39NQRR923 pKa = 11.84AWNIWEE929 pKa = 3.99VEE931 pKa = 4.23DD932 pKa = 3.7YY933 pKa = 11.4GFGIFTTNIWLKK945 pKa = 10.9LRR947 pKa = 11.84DD948 pKa = 4.27SYY950 pKa = 11.22TQVCDD955 pKa = 3.5HH956 pKa = 7.11RR957 pKa = 11.84LMSAAIKK964 pKa = 10.21DD965 pKa = 4.11SKK967 pKa = 10.97AVHH970 pKa = 6.87ADD972 pKa = 2.79MGYY975 pKa = 9.92WIEE978 pKa = 4.18SEE980 pKa = 5.22KK981 pKa = 11.42NEE983 pKa = 4.0TWKK986 pKa = 10.58LARR989 pKa = 11.84ASFIEE994 pKa = 4.48VKK996 pKa = 9.62TCIWPKK1002 pKa = 10.89SHH1004 pKa = 6.34TLWSNGVLEE1013 pKa = 4.74SEE1015 pKa = 4.42MIIPKK1020 pKa = 9.94IYY1022 pKa = 10.32GGPISQHH1029 pKa = 5.65NYY1031 pKa = 7.73RR1032 pKa = 11.84PGYY1035 pKa = 7.79FTQTAGPWHH1044 pKa = 6.7LGKK1047 pKa = 10.78LEE1049 pKa = 4.9LDD1051 pKa = 3.49FDD1053 pKa = 4.42LCEE1056 pKa = 4.3GTTVVVDD1063 pKa = 4.03EE1064 pKa = 4.69HH1065 pKa = 6.96CGNRR1069 pKa = 11.84GPSLRR1074 pKa = 11.84TTTVTGKK1081 pKa = 8.73TIHH1084 pKa = 5.87EE1085 pKa = 4.36WCCRR1089 pKa = 11.84SCTLPPLRR1097 pKa = 11.84FKK1099 pKa = 11.55GEE1101 pKa = 4.0DD1102 pKa = 3.57GCWYY1106 pKa = 10.41GMEE1109 pKa = 3.79IRR1111 pKa = 11.84PVKK1114 pKa = 10.26EE1115 pKa = 3.7KK1116 pKa = 11.14EE1117 pKa = 3.95EE1118 pKa = 4.02NLVKK1122 pKa = 11.04SMVSAGSGEE1131 pKa = 3.98VDD1133 pKa = 3.54SFSLGLLCISIMIEE1147 pKa = 3.51EE1148 pKa = 4.47VMRR1151 pKa = 11.84SRR1153 pKa = 11.84WSRR1156 pKa = 11.84KK1157 pKa = 6.9MLMTGTLAVFLLLTMGQLTWNDD1179 pKa = 4.68LIRR1182 pKa = 11.84LCIMVGANASDD1193 pKa = 3.29KK1194 pKa = 10.5MGMGTTYY1201 pKa = 10.5LALMATFRR1209 pKa = 11.84MRR1211 pKa = 11.84PMFAVGLLFRR1221 pKa = 11.84RR1222 pKa = 11.84LTSRR1226 pKa = 11.84EE1227 pKa = 3.9VLLLTVGLSLVASVEE1242 pKa = 4.26LPNSLEE1248 pKa = 3.9EE1249 pKa = 4.67LGDD1252 pKa = 3.87GLAMGIMMLKK1262 pKa = 10.53LLTDD1266 pKa = 4.53FQSHH1270 pKa = 5.2QLWATLLSLTFVKK1283 pKa = 8.49TTFSLHH1289 pKa = 5.33YY1290 pKa = 9.25AWKK1293 pKa = 7.62TMAMILSIVSLFPLCLSTTSQKK1315 pKa = 7.27TTWLPVLLGSLGCKK1329 pKa = 8.97PLTMFLITEE1338 pKa = 3.97NKK1340 pKa = 8.13IWGRR1344 pKa = 11.84KK1345 pKa = 6.75SWPLNEE1351 pKa = 5.26GIMAVGIVSILLSSLLKK1368 pKa = 10.6NDD1370 pKa = 3.31VPLAGPLIAGGMLIACYY1387 pKa = 10.15VISGSSADD1395 pKa = 3.94LSLEE1399 pKa = 3.89KK1400 pKa = 10.33AAEE1403 pKa = 4.17VSWEE1407 pKa = 3.94EE1408 pKa = 4.03EE1409 pKa = 4.33AEE1411 pKa = 4.17HH1412 pKa = 6.88SGASHH1417 pKa = 6.97NILVEE1422 pKa = 4.1VQDD1425 pKa = 4.78DD1426 pKa = 3.94GTMKK1430 pKa = 10.51IKK1432 pKa = 10.75DD1433 pKa = 3.82EE1434 pKa = 4.24EE1435 pKa = 4.85RR1436 pKa = 11.84DD1437 pKa = 3.59DD1438 pKa = 3.86TLTILLKK1445 pKa = 10.18ATLLAISGVYY1455 pKa = 9.83PMSIPATLFVWYY1467 pKa = 8.75FWQKK1471 pKa = 9.31KK1472 pKa = 5.95KK1473 pKa = 10.45QRR1475 pKa = 11.84SGVLWDD1481 pKa = 3.93TPSPPEE1487 pKa = 3.79VEE1489 pKa = 4.37RR1490 pKa = 11.84AVLDD1494 pKa = 3.98DD1495 pKa = 4.63GIYY1498 pKa = 10.39RR1499 pKa = 11.84ILQRR1503 pKa = 11.84GLLGRR1508 pKa = 11.84SQVGVGVFQEE1518 pKa = 5.15GVFHH1522 pKa = 6.02TMWHH1526 pKa = 4.42VTRR1529 pKa = 11.84GAVLMYY1535 pKa = 9.65QGKK1538 pKa = 9.43RR1539 pKa = 11.84LEE1541 pKa = 4.36PSWASVKK1548 pKa = 10.34KK1549 pKa = 10.68DD1550 pKa = 3.64LISYY1554 pKa = 8.63GGGWRR1559 pKa = 11.84FQGSWNAGEE1568 pKa = 4.24EE1569 pKa = 4.34VQVIAVEE1576 pKa = 4.09PGKK1579 pKa = 10.35NPKK1582 pKa = 9.42NVQTAPGTFKK1592 pKa = 10.63TPEE1595 pKa = 4.28GEE1597 pKa = 4.21VGAIALDD1604 pKa = 4.22FKK1606 pKa = 10.64PGTSGSPIVNRR1617 pKa = 11.84EE1618 pKa = 3.57GKK1620 pKa = 9.91IVGLYY1625 pKa = 10.43GNGVVTTSGTYY1636 pKa = 10.13VSAIAQAKK1644 pKa = 9.63ASQEE1648 pKa = 4.02GPLPEE1653 pKa = 6.06IEE1655 pKa = 5.06DD1656 pKa = 3.5EE1657 pKa = 4.52VFRR1660 pKa = 11.84KK1661 pKa = 10.12RR1662 pKa = 11.84NLTIMDD1668 pKa = 4.22LHH1670 pKa = 6.68PGSGKK1675 pKa = 7.11TRR1677 pKa = 11.84RR1678 pKa = 11.84YY1679 pKa = 9.3LPAIVRR1685 pKa = 11.84EE1686 pKa = 4.34AIRR1689 pKa = 11.84RR1690 pKa = 11.84NVRR1693 pKa = 11.84TLVLAPTRR1701 pKa = 11.84VVASEE1706 pKa = 3.69MAEE1709 pKa = 4.01ALKK1712 pKa = 10.75GMPIRR1717 pKa = 11.84YY1718 pKa = 6.77QTTAVKK1724 pKa = 10.43SEE1726 pKa = 4.02HH1727 pKa = 5.71TGKK1730 pKa = 10.83EE1731 pKa = 4.07IVDD1734 pKa = 4.09LMCHH1738 pKa = 5.31ATFTMRR1744 pKa = 11.84LLSPVRR1750 pKa = 11.84VPNYY1754 pKa = 10.79NMIIMDD1760 pKa = 4.22EE1761 pKa = 4.12AHH1763 pKa = 6.01FTDD1766 pKa = 4.51PASIAARR1773 pKa = 11.84GYY1775 pKa = 8.52ISTRR1779 pKa = 11.84VGMGEE1784 pKa = 3.54AAAIFMTATPPGSVEE1799 pKa = 5.35AFPQSNAVIQDD1810 pKa = 3.52EE1811 pKa = 4.29EE1812 pKa = 4.85RR1813 pKa = 11.84DD1814 pKa = 3.5IPEE1817 pKa = 4.2RR1818 pKa = 11.84SWNSGYY1824 pKa = 11.2DD1825 pKa = 3.34WITDD1829 pKa = 3.96FPGKK1833 pKa = 7.84TVWFVPSIKK1842 pKa = 10.33SGNDD1846 pKa = 2.71IANCLRR1852 pKa = 11.84KK1853 pKa = 9.55NGKK1856 pKa = 9.33RR1857 pKa = 11.84VVQLSRR1863 pKa = 11.84KK1864 pKa = 7.57TFDD1867 pKa = 2.99TEE1869 pKa = 4.1YY1870 pKa = 11.09QKK1872 pKa = 9.79TKK1874 pKa = 10.86NNDD1877 pKa = 2.44WDD1879 pKa = 4.24YY1880 pKa = 12.01VVTTDD1885 pKa = 4.45ISEE1888 pKa = 3.91MGANFRR1894 pKa = 11.84ADD1896 pKa = 3.41RR1897 pKa = 11.84VIDD1900 pKa = 3.66PRR1902 pKa = 11.84RR1903 pKa = 11.84CLKK1906 pKa = 10.44PVILKK1911 pKa = 10.18DD1912 pKa = 3.38GPEE1915 pKa = 3.91RR1916 pKa = 11.84VILAGPMPVTVASAAQRR1933 pKa = 11.84RR1934 pKa = 11.84GRR1936 pKa = 11.84IGRR1939 pKa = 11.84NQNKK1943 pKa = 10.16EE1944 pKa = 3.51GDD1946 pKa = 3.43QYY1948 pKa = 11.59IYY1950 pKa = 10.15MGQPLNNDD1958 pKa = 3.21EE1959 pKa = 5.49DD1960 pKa = 4.12HH1961 pKa = 6.89AHH1963 pKa = 5.06WTEE1966 pKa = 4.43AKK1968 pKa = 9.72MLLDD1972 pKa = 5.03NINTPEE1978 pKa = 4.5GIIPALFEE1986 pKa = 4.23PEE1988 pKa = 4.14RR1989 pKa = 11.84EE1990 pKa = 3.79KK1991 pKa = 11.15SAAIDD1996 pKa = 3.31GEE1998 pKa = 4.15YY1999 pKa = 10.51RR2000 pKa = 11.84LRR2002 pKa = 11.84GEE2004 pKa = 3.83ARR2006 pKa = 11.84KK2007 pKa = 7.94TFVEE2011 pKa = 3.99LMRR2014 pKa = 11.84RR2015 pKa = 11.84GDD2017 pKa = 3.69LPVWLSYY2024 pKa = 10.64KK2025 pKa = 9.95VASEE2029 pKa = 4.24GFQYY2033 pKa = 11.02SDD2035 pKa = 4.56RR2036 pKa = 11.84RR2037 pKa = 11.84WCFDD2041 pKa = 3.23GEE2043 pKa = 4.36RR2044 pKa = 11.84NNQVLEE2050 pKa = 4.08EE2051 pKa = 4.15NMDD2054 pKa = 3.47VEE2056 pKa = 4.4IWTKK2060 pKa = 9.93EE2061 pKa = 3.93GEE2063 pKa = 4.39RR2064 pKa = 11.84KK2065 pKa = 9.68KK2066 pKa = 10.87LRR2068 pKa = 11.84PRR2070 pKa = 11.84WLDD2073 pKa = 2.83ARR2075 pKa = 11.84TYY2077 pKa = 10.93SDD2079 pKa = 3.77PLALRR2084 pKa = 11.84EE2085 pKa = 4.21FKK2087 pKa = 10.68EE2088 pKa = 4.26FAAGRR2093 pKa = 11.84RR2094 pKa = 11.84SVSGDD2099 pKa = 3.72LILEE2103 pKa = 4.24IGKK2106 pKa = 9.51LPQHH2110 pKa = 6.06LTQRR2114 pKa = 11.84AQNALDD2120 pKa = 3.8NLVMLHH2126 pKa = 6.37NSEE2129 pKa = 4.42QGGKK2133 pKa = 9.83AYY2135 pKa = 10.2RR2136 pKa = 11.84HH2137 pKa = 5.8AMEE2140 pKa = 5.09EE2141 pKa = 4.15LPDD2144 pKa = 4.28TIEE2147 pKa = 3.97TLMLLALIAVLTGGVTLFFLSGRR2170 pKa = 11.84GLGKK2174 pKa = 9.19TSIGLLCVIASSALLWMASVEE2195 pKa = 4.2PHH2197 pKa = 6.88WIAASIILEE2206 pKa = 4.12FFLMVLLIPEE2216 pKa = 5.06PDD2218 pKa = 3.44RR2219 pKa = 11.84QRR2221 pKa = 11.84TPQDD2225 pKa = 2.98NQLAYY2230 pKa = 10.77VVIGLLFMILTAAANEE2246 pKa = 4.06MGLLEE2251 pKa = 4.31TTKK2254 pKa = 10.59KK2255 pKa = 10.79DD2256 pKa = 3.54LGIGHH2261 pKa = 7.65AAAEE2265 pKa = 4.37NHH2267 pKa = 5.7HH2268 pKa = 6.71HH2269 pKa = 7.0AAMLDD2274 pKa = 3.67VDD2276 pKa = 4.71LHH2278 pKa = 6.34PASAWTLYY2286 pKa = 10.76AVATTIITPMMRR2298 pKa = 11.84HH2299 pKa = 5.58TIEE2302 pKa = 3.87NTTANISLTAIANQAAILMGLDD2324 pKa = 3.48KK2325 pKa = 10.85GWPISKK2331 pKa = 9.37MDD2333 pKa = 3.33IGVPLLALGCYY2344 pKa = 9.67SQVNPLTLTAAVFMLVAHH2362 pKa = 6.12YY2363 pKa = 10.42AIIGPGLQAKK2373 pKa = 7.77ATRR2376 pKa = 11.84EE2377 pKa = 4.13AQKK2380 pKa = 9.55RR2381 pKa = 11.84TAAGIMKK2388 pKa = 9.99NPTVDD2393 pKa = 4.06GIVAIDD2399 pKa = 4.75LDD2401 pKa = 4.16PVVYY2405 pKa = 9.93DD2406 pKa = 4.7AKK2408 pKa = 10.89FEE2410 pKa = 4.13KK2411 pKa = 10.53QLGQIMLLILCTSQILLMRR2430 pKa = 11.84TTWALCEE2437 pKa = 4.51SITLATGPLTTLWEE2451 pKa = 4.47GSPGKK2456 pKa = 10.02FWNTTIAVSMANIFRR2471 pKa = 11.84GSYY2474 pKa = 9.71LAGAGLAFSLMKK2486 pKa = 10.64SLGGGRR2492 pKa = 11.84RR2493 pKa = 11.84GTGAQGEE2500 pKa = 4.56TLGEE2504 pKa = 3.74KK2505 pKa = 9.33WKK2507 pKa = 10.64RR2508 pKa = 11.84QLNQLSKK2515 pKa = 11.28SEE2517 pKa = 3.91FNTYY2521 pKa = 9.24KK2522 pKa = 10.2RR2523 pKa = 11.84SGIIEE2528 pKa = 4.01VDD2530 pKa = 2.94RR2531 pKa = 11.84SEE2533 pKa = 4.56AKK2535 pKa = 10.18EE2536 pKa = 3.73GLKK2539 pKa = 10.45RR2540 pKa = 11.84GEE2542 pKa = 4.16PTKK2545 pKa = 10.51HH2546 pKa = 5.05AVSRR2550 pKa = 11.84GTAKK2554 pKa = 10.44LRR2556 pKa = 11.84WFVEE2560 pKa = 4.14RR2561 pKa = 11.84NLVKK2565 pKa = 10.73PEE2567 pKa = 3.92GKK2569 pKa = 10.64VIDD2572 pKa = 4.49LGCGRR2577 pKa = 11.84GGWSYY2582 pKa = 11.91YY2583 pKa = 10.16CAGLKK2588 pKa = 10.18KK2589 pKa = 8.7VTEE2592 pKa = 4.19VKK2594 pKa = 10.61GYY2596 pKa = 8.05TKK2598 pKa = 10.49GGPGHH2603 pKa = 6.42EE2604 pKa = 4.59EE2605 pKa = 4.67PIPMATYY2612 pKa = 9.68GWNLVKK2618 pKa = 10.47LYY2620 pKa = 10.43SGKK2623 pKa = 10.33DD2624 pKa = 3.3VFFTPPEE2631 pKa = 4.11KK2632 pKa = 10.45CDD2634 pKa = 3.7TLLCDD2639 pKa = 4.45IGEE2642 pKa = 4.31SSPNPTIEE2650 pKa = 3.73EE2651 pKa = 4.22GRR2653 pKa = 11.84TLRR2656 pKa = 11.84VLKK2659 pKa = 10.05MVEE2662 pKa = 3.2PWLRR2666 pKa = 11.84GNQFCIKK2673 pKa = 9.83ILNPYY2678 pKa = 8.29MPSVVEE2684 pKa = 4.26TLEE2687 pKa = 3.79QMQRR2691 pKa = 11.84KK2692 pKa = 8.22HH2693 pKa = 7.41GGMLVRR2699 pKa = 11.84NPLSRR2704 pKa = 11.84NSTHH2708 pKa = 4.89EE2709 pKa = 4.41MYY2711 pKa = 9.64WVSCGTGNIVSAVNMTSRR2729 pKa = 11.84MLLNRR2734 pKa = 11.84FTMAHH2739 pKa = 6.78RR2740 pKa = 11.84KK2741 pKa = 6.35PTYY2744 pKa = 10.1EE2745 pKa = 4.03RR2746 pKa = 11.84DD2747 pKa = 3.15VDD2749 pKa = 4.17LGAGTRR2755 pKa = 11.84HH2756 pKa = 5.3VAVEE2760 pKa = 4.15PEE2762 pKa = 4.22VANLDD2767 pKa = 3.79IIGQRR2772 pKa = 11.84IEE2774 pKa = 4.15NIKK2777 pKa = 10.58NGHH2780 pKa = 6.27KK2781 pKa = 9.46STWHH2785 pKa = 5.69YY2786 pKa = 11.74DD2787 pKa = 3.03EE2788 pKa = 6.14DD2789 pKa = 4.07NPYY2792 pKa = 8.4KK2793 pKa = 9.24TWAYY2797 pKa = 9.37HH2798 pKa = 5.42GSYY2801 pKa = 9.2EE2802 pKa = 4.27VKK2804 pKa = 10.27PSGSASSMVNGVVRR2818 pKa = 11.84LLTKK2822 pKa = 9.75PWDD2825 pKa = 4.11VIPMVTQIAMTDD2837 pKa = 3.36TTPFGQQRR2845 pKa = 11.84VFKK2848 pKa = 9.7EE2849 pKa = 4.16KK2850 pKa = 10.85VDD2852 pKa = 3.51TRR2854 pKa = 11.84TPKK2857 pKa = 10.56AKK2859 pKa = 10.27RR2860 pKa = 11.84GTAQIMEE2867 pKa = 4.41VTARR2871 pKa = 11.84WLWGFLSRR2879 pKa = 11.84NKK2881 pKa = 10.08KK2882 pKa = 9.69PRR2884 pKa = 11.84ICTRR2888 pKa = 11.84EE2889 pKa = 3.52EE2890 pKa = 3.56FTRR2893 pKa = 11.84KK2894 pKa = 9.1VRR2896 pKa = 11.84SNAAIGAVFVDD2907 pKa = 3.83EE2908 pKa = 4.62NQWNSAKK2915 pKa = 10.46EE2916 pKa = 3.83AVEE2919 pKa = 5.68DD2920 pKa = 3.66EE2921 pKa = 4.54RR2922 pKa = 11.84FWDD2925 pKa = 3.74LVHH2928 pKa = 7.7RR2929 pKa = 11.84EE2930 pKa = 4.11RR2931 pKa = 11.84EE2932 pKa = 3.85LHH2934 pKa = 5.9KK2935 pKa = 10.5QGKK2938 pKa = 8.89CATCVYY2944 pKa = 11.26NMMGKK2949 pKa = 9.2RR2950 pKa = 11.84EE2951 pKa = 4.01KK2952 pKa = 10.78KK2953 pKa = 10.17LGEE2956 pKa = 3.75FGKK2959 pKa = 10.75AKK2961 pKa = 10.05GSRR2964 pKa = 11.84AIWYY2968 pKa = 7.23MWLGARR2974 pKa = 11.84FLEE2977 pKa = 4.92FEE2979 pKa = 4.47ALGFMNEE2986 pKa = 4.06DD2987 pKa = 2.72HH2988 pKa = 6.43WFSRR2992 pKa = 11.84EE2993 pKa = 3.69NSLSGVEE3000 pKa = 4.56GEE3002 pKa = 4.68GLHH3005 pKa = 5.91KK3006 pKa = 10.51LGYY3009 pKa = 9.24ILRR3012 pKa = 11.84DD3013 pKa = 3.12ISKK3016 pKa = 10.14IPGGNMYY3023 pKa = 10.95ADD3025 pKa = 4.59DD3026 pKa = 3.74TAGWDD3031 pKa = 3.53TRR3033 pKa = 11.84ITEE3036 pKa = 5.16DD3037 pKa = 5.0DD3038 pKa = 4.04LQNEE3042 pKa = 4.31AKK3044 pKa = 8.93ITDD3047 pKa = 3.3IMEE3050 pKa = 4.53PEE3052 pKa = 4.12HH3053 pKa = 6.91ALLATSIFKK3062 pKa = 8.87LTYY3065 pKa = 7.31QNKK3068 pKa = 7.62VVRR3071 pKa = 11.84VQRR3074 pKa = 11.84PAKK3077 pKa = 9.71NGTVMDD3083 pKa = 4.68VISRR3087 pKa = 11.84RR3088 pKa = 11.84DD3089 pKa = 3.28QRR3091 pKa = 11.84GSGQVGTYY3099 pKa = 10.37GLNTFTNMEE3108 pKa = 4.08AQLIRR3113 pKa = 11.84QMEE3116 pKa = 4.39SEE3118 pKa = 5.04GIFSPSEE3125 pKa = 3.93LEE3127 pKa = 4.24TPNLAEE3133 pKa = 5.96RR3134 pKa = 11.84VLDD3137 pKa = 3.47WLKK3140 pKa = 10.93KK3141 pKa = 10.07HH3142 pKa = 4.62GTEE3145 pKa = 3.65RR3146 pKa = 11.84LKK3148 pKa = 11.21RR3149 pKa = 11.84MAISGDD3155 pKa = 3.62DD3156 pKa = 3.78CVVKK3160 pKa = 10.53PIDD3163 pKa = 4.51DD3164 pKa = 4.05RR3165 pKa = 11.84FATALTALNDD3175 pKa = 3.51MGKK3178 pKa = 9.4VRR3180 pKa = 11.84KK3181 pKa = 9.54DD3182 pKa = 3.03IPQWEE3187 pKa = 4.28PSKK3190 pKa = 11.09GWNDD3194 pKa = 3.14WQQVPFCSHH3203 pKa = 7.0HH3204 pKa = 4.87FHH3206 pKa = 6.36QLIMKK3211 pKa = 9.27DD3212 pKa = 2.94GRR3214 pKa = 11.84EE3215 pKa = 3.84IVVPCRR3221 pKa = 11.84NQDD3224 pKa = 3.56EE3225 pKa = 4.67LVGRR3229 pKa = 11.84ARR3231 pKa = 11.84VSQGAGWSLRR3241 pKa = 11.84EE3242 pKa = 3.93TACLGKK3248 pKa = 10.26SYY3250 pKa = 11.13AQMWQLMYY3258 pKa = 9.12FHH3260 pKa = 7.15RR3261 pKa = 11.84RR3262 pKa = 11.84DD3263 pKa = 3.23LRR3265 pKa = 11.84LAANAICSAVPVDD3278 pKa = 3.81WVPTSRR3284 pKa = 11.84TTWSIHH3290 pKa = 5.75AHH3292 pKa = 5.0HH3293 pKa = 6.22QWMTTEE3299 pKa = 4.99DD3300 pKa = 4.28MLSVWNRR3307 pKa = 11.84VWIEE3311 pKa = 3.77EE3312 pKa = 4.24NPWMEE3317 pKa = 4.8DD3318 pKa = 3.06KK3319 pKa = 10.48THH3321 pKa = 5.48VSSWEE3326 pKa = 3.82DD3327 pKa = 3.19VPYY3330 pKa = 10.56LGKK3333 pKa = 10.38RR3334 pKa = 11.84EE3335 pKa = 4.05DD3336 pKa = 3.46RR3337 pKa = 11.84WCGSLIGLTARR3348 pKa = 11.84ATWATNIQVAINQVRR3363 pKa = 11.84RR3364 pKa = 11.84LIGNEE3369 pKa = 3.58NYY3371 pKa = 10.61LDD3373 pKa = 3.95FMTSMKK3379 pKa = 10.28RR3380 pKa = 11.84FKK3382 pKa = 11.01NEE3384 pKa = 3.71SDD3386 pKa = 3.59PEE3388 pKa = 4.2GALWW3392 pKa = 3.93

Molecular weight:
378.7 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|P17763|POLG_DEN1W Genome polyprotein OS=Dengue virus type 1 (strain Nauru/West Pac/1974) OX=11059 PE=1 SV=2
MM1 pKa = 7.38NNQRR5 pKa = 11.84KK6 pKa = 7.83KK7 pKa = 8.92TGRR10 pKa = 11.84PSFNMLKK17 pKa = 10.18RR18 pKa = 11.84ARR20 pKa = 11.84NRR22 pKa = 11.84VSTVSQLAKK31 pKa = 10.25RR32 pKa = 11.84FSKK35 pKa = 10.85GLLSGQGPMKK45 pKa = 10.59LVMAFIAFLRR55 pKa = 11.84FLAIPPTAGILARR68 pKa = 11.84WGSFKK73 pKa = 11.04KK74 pKa = 10.57NGAIKK79 pKa = 10.3VLRR82 pKa = 11.84GFKK85 pKa = 10.5KK86 pKa = 10.41EE87 pKa = 3.64ISNMLNIMNRR97 pKa = 11.84RR98 pKa = 11.84KK99 pKa = 10.18RR100 pKa = 11.84SVTMLLMLLPTALAFHH116 pKa = 6.92LTTRR120 pKa = 11.84GGEE123 pKa = 3.66PHH125 pKa = 6.74MIVSKK130 pKa = 8.28QEE132 pKa = 3.76RR133 pKa = 11.84GKK135 pKa = 10.85SLLFKK140 pKa = 10.42TSAGVNMCTLIAMDD154 pKa = 5.01LGEE157 pKa = 4.53LCEE160 pKa = 4.23DD161 pKa = 3.5TMTYY165 pKa = 9.35KK166 pKa = 10.65CPRR169 pKa = 11.84ITEE172 pKa = 4.26TEE174 pKa = 4.12PDD176 pKa = 6.07DD177 pKa = 4.27VDD179 pKa = 3.64CWCNATEE186 pKa = 4.01TWVTYY191 pKa = 7.35GTCSQTGEE199 pKa = 3.75HH200 pKa = 6.46RR201 pKa = 11.84RR202 pKa = 11.84DD203 pKa = 3.38KK204 pKa = 10.95RR205 pKa = 11.84SVALAPHH212 pKa = 6.3VGLGLEE218 pKa = 4.45TRR220 pKa = 11.84TEE222 pKa = 3.81TWMSSEE228 pKa = 4.24GAWKK232 pKa = 10.05QIQKK236 pKa = 9.99VEE238 pKa = 4.0TWALRR243 pKa = 11.84HH244 pKa = 6.23PGFTVIALFLAHH256 pKa = 7.64AIGTSITQKK265 pKa = 10.92GIIFILLMLVTPSMAMRR282 pKa = 11.84CVGIGNRR289 pKa = 11.84DD290 pKa = 3.44FVEE293 pKa = 4.55GLSGATWVDD302 pKa = 3.42VVLEE306 pKa = 4.39HH307 pKa = 6.6GSCVTTMAKK316 pKa = 10.26DD317 pKa = 3.36KK318 pKa = 8.44PTLDD322 pKa = 3.19IEE324 pKa = 4.32LLKK327 pKa = 10.49TEE329 pKa = 4.21VTNPAVLRR337 pKa = 11.84KK338 pKa = 9.89LCIEE342 pKa = 4.17AKK344 pKa = 10.1ISNTTTDD351 pKa = 3.5SRR353 pKa = 11.84CPTQGEE359 pKa = 4.1ATLVEE364 pKa = 4.24EE365 pKa = 3.99QDD367 pKa = 3.68TNFVCRR373 pKa = 11.84RR374 pKa = 11.84TFVDD378 pKa = 3.54RR379 pKa = 11.84GWGNGCGLFGKK390 pKa = 10.7GSLITCAKK398 pKa = 8.56FKK400 pKa = 10.84CVTKK404 pKa = 11.04LEE406 pKa = 4.34GKK408 pKa = 9.57IVQYY412 pKa = 11.26EE413 pKa = 3.93NLKK416 pKa = 9.73YY417 pKa = 10.19SVIVTVHH424 pKa = 6.31TGDD427 pKa = 3.11QHH429 pKa = 6.63QVGNEE434 pKa = 4.04TTEE437 pKa = 4.05HH438 pKa = 6.03GTTATITPQAPTSEE452 pKa = 4.26IQLTDD457 pKa = 3.56YY458 pKa = 11.24GALTLDD464 pKa = 3.9CSPRR468 pKa = 11.84TGLDD472 pKa = 3.3FNEE475 pKa = 4.28MVLLTMEE482 pKa = 4.33KK483 pKa = 10.38KK484 pKa = 9.7SWLVHH489 pKa = 5.22KK490 pKa = 10.27QWFLDD495 pKa = 4.68LPLPWTSGASTSQEE509 pKa = 3.26TWNRR513 pKa = 11.84QDD515 pKa = 4.38LLVTFKK521 pKa = 10.04TAHH524 pKa = 6.18AKK526 pKa = 8.85KK527 pKa = 10.34QEE529 pKa = 4.03VVVLGSQEE537 pKa = 4.23GAMHH541 pKa = 6.57TALTGATEE549 pKa = 4.19IQTSGTTTIFAGHH562 pKa = 6.79LKK564 pKa = 10.4CRR566 pKa = 11.84LKK568 pKa = 10.03MDD570 pKa = 3.68KK571 pKa = 9.94LTLKK575 pKa = 10.46GMSYY579 pKa = 10.82VMCTGSFKK587 pKa = 10.99LEE589 pKa = 3.96KK590 pKa = 10.14EE591 pKa = 4.38VAEE594 pKa = 4.43TQHH597 pKa = 5.63GTVLVQVKK605 pKa = 10.01YY606 pKa = 10.26EE607 pKa = 4.17GTDD610 pKa = 3.59APCKK614 pKa = 10.24IPFSSQDD621 pKa = 3.42EE622 pKa = 4.43KK623 pKa = 11.59GVTQNGRR630 pKa = 11.84LITANPIVTDD640 pKa = 3.34KK641 pKa = 10.59EE642 pKa = 4.19KK643 pKa = 10.61PVNIEE648 pKa = 3.65AEE650 pKa = 4.26PPFGEE655 pKa = 4.4SYY657 pKa = 10.55IVVGAGEE664 pKa = 4.29KK665 pKa = 10.22ALKK668 pKa = 10.56LSWFKK673 pKa = 10.84KK674 pKa = 9.44GSSIGKK680 pKa = 8.45MFEE683 pKa = 3.59ATARR687 pKa = 11.84GARR690 pKa = 11.84RR691 pKa = 11.84MAILGDD697 pKa = 3.83TAWDD701 pKa = 3.93FGSIGGVFTSVGKK714 pKa = 10.4LIHH717 pKa = 6.32QIFGTAYY724 pKa = 7.96GVLFSGVSWTMKK736 pKa = 9.93IGIGILLTWLGLNSRR751 pKa = 11.84STSLSMTCIAVGMVTLYY768 pKa = 10.85LGVMVQADD776 pKa = 4.31SGCVINWKK784 pKa = 10.03GRR786 pKa = 11.84EE787 pKa = 4.12LKK789 pKa = 10.31CGSGIFVTNEE799 pKa = 3.11VHH801 pKa = 6.28TWTEE805 pKa = 3.82QYY807 pKa = 10.86KK808 pKa = 9.78FQADD812 pKa = 3.64SPKK815 pKa = 10.31RR816 pKa = 11.84LSAAIGKK823 pKa = 8.88AWEE826 pKa = 4.27EE827 pKa = 4.47GVCGIRR833 pKa = 11.84SATRR837 pKa = 11.84LEE839 pKa = 4.17NIMWKK844 pKa = 10.26QISNEE849 pKa = 3.92LNHH852 pKa = 6.9ILLEE856 pKa = 4.14NDD858 pKa = 3.13MKK860 pKa = 10.51FTVVVGDD867 pKa = 3.21VSGILAQGKK876 pKa = 10.14KK877 pKa = 9.36MIRR880 pKa = 11.84PQPMEE885 pKa = 4.55HH886 pKa = 6.71KK887 pKa = 10.44YY888 pKa = 10.29SWKK891 pKa = 9.89SWGKK895 pKa = 10.54AKK897 pKa = 10.46IIGADD902 pKa = 3.48VQNTTFIIDD911 pKa = 3.81GPNTPEE917 pKa = 4.54CPDD920 pKa = 3.39NQRR923 pKa = 11.84AWNIWEE929 pKa = 3.99VEE931 pKa = 4.23DD932 pKa = 3.7YY933 pKa = 11.4GFGIFTTNIWLKK945 pKa = 10.9LRR947 pKa = 11.84DD948 pKa = 4.27SYY950 pKa = 11.22TQVCDD955 pKa = 3.5HH956 pKa = 7.11RR957 pKa = 11.84LMSAAIKK964 pKa = 10.21DD965 pKa = 4.11SKK967 pKa = 10.97AVHH970 pKa = 6.87ADD972 pKa = 2.79MGYY975 pKa = 9.92WIEE978 pKa = 4.18SEE980 pKa = 5.22KK981 pKa = 11.42NEE983 pKa = 4.0TWKK986 pKa = 10.58LARR989 pKa = 11.84ASFIEE994 pKa = 4.48VKK996 pKa = 9.62TCIWPKK1002 pKa = 10.89SHH1004 pKa = 6.34TLWSNGVLEE1013 pKa = 4.74SEE1015 pKa = 4.42MIIPKK1020 pKa = 9.94IYY1022 pKa = 10.32GGPISQHH1029 pKa = 5.65NYY1031 pKa = 7.73RR1032 pKa = 11.84PGYY1035 pKa = 7.79FTQTAGPWHH1044 pKa = 6.7LGKK1047 pKa = 10.78LEE1049 pKa = 4.9LDD1051 pKa = 3.49FDD1053 pKa = 4.42LCEE1056 pKa = 4.3GTTVVVDD1063 pKa = 4.03EE1064 pKa = 4.69HH1065 pKa = 6.96CGNRR1069 pKa = 11.84GPSLRR1074 pKa = 11.84TTTVTGKK1081 pKa = 8.73TIHH1084 pKa = 5.87EE1085 pKa = 4.36WCCRR1089 pKa = 11.84SCTLPPLRR1097 pKa = 11.84FKK1099 pKa = 11.55GEE1101 pKa = 4.0DD1102 pKa = 3.57GCWYY1106 pKa = 10.41GMEE1109 pKa = 3.79IRR1111 pKa = 11.84PVKK1114 pKa = 10.26EE1115 pKa = 3.7KK1116 pKa = 11.14EE1117 pKa = 3.95EE1118 pKa = 4.02NLVKK1122 pKa = 11.04SMVSAGSGEE1131 pKa = 3.98VDD1133 pKa = 3.54SFSLGLLCISIMIEE1147 pKa = 3.51EE1148 pKa = 4.47VMRR1151 pKa = 11.84SRR1153 pKa = 11.84WSRR1156 pKa = 11.84KK1157 pKa = 6.9MLMTGTLAVFLLLTMGQLTWNDD1179 pKa = 4.68LIRR1182 pKa = 11.84LCIMVGANASDD1193 pKa = 3.29KK1194 pKa = 10.5MGMGTTYY1201 pKa = 10.5LALMATFRR1209 pKa = 11.84MRR1211 pKa = 11.84PMFAVGLLFRR1221 pKa = 11.84RR1222 pKa = 11.84LTSRR1226 pKa = 11.84EE1227 pKa = 3.9VLLLTVGLSLVASVEE1242 pKa = 4.26LPNSLEE1248 pKa = 3.9EE1249 pKa = 4.67LGDD1252 pKa = 3.87GLAMGIMMLKK1262 pKa = 10.53LLTDD1266 pKa = 4.53FQSHH1270 pKa = 5.2QLWATLLSLTFVKK1283 pKa = 8.49TTFSLHH1289 pKa = 5.33YY1290 pKa = 9.25AWKK1293 pKa = 7.62TMAMILSIVSLFPLCLSTTSQKK1315 pKa = 7.27TTWLPVLLGSLGCKK1329 pKa = 8.97PLTMFLITEE1338 pKa = 3.97NKK1340 pKa = 8.13IWGRR1344 pKa = 11.84KK1345 pKa = 6.75SWPLNEE1351 pKa = 5.26GIMAVGIVSILLSSLLKK1368 pKa = 10.6NDD1370 pKa = 3.31VPLAGPLIAGGMLIACYY1387 pKa = 10.15VISGSSADD1395 pKa = 3.94LSLEE1399 pKa = 3.89KK1400 pKa = 10.33AAEE1403 pKa = 4.17VSWEE1407 pKa = 3.94EE1408 pKa = 4.03EE1409 pKa = 4.33AEE1411 pKa = 4.17HH1412 pKa = 6.88SGASHH1417 pKa = 6.97NILVEE1422 pKa = 4.1VQDD1425 pKa = 4.78DD1426 pKa = 3.94GTMKK1430 pKa = 10.51IKK1432 pKa = 10.75DD1433 pKa = 3.82EE1434 pKa = 4.24EE1435 pKa = 4.85RR1436 pKa = 11.84DD1437 pKa = 3.59DD1438 pKa = 3.86TLTILLKK1445 pKa = 10.18ATLLAISGVYY1455 pKa = 9.83PMSIPATLFVWYY1467 pKa = 8.75FWQKK1471 pKa = 9.31KK1472 pKa = 5.95KK1473 pKa = 10.45QRR1475 pKa = 11.84SGVLWDD1481 pKa = 3.93TPSPPEE1487 pKa = 3.79VEE1489 pKa = 4.37RR1490 pKa = 11.84AVLDD1494 pKa = 3.98DD1495 pKa = 4.63GIYY1498 pKa = 10.39RR1499 pKa = 11.84ILQRR1503 pKa = 11.84GLLGRR1508 pKa = 11.84SQVGVGVFQEE1518 pKa = 5.15GVFHH1522 pKa = 6.02TMWHH1526 pKa = 4.42VTRR1529 pKa = 11.84GAVLMYY1535 pKa = 9.65QGKK1538 pKa = 9.43RR1539 pKa = 11.84LEE1541 pKa = 4.36PSWASVKK1548 pKa = 10.34KK1549 pKa = 10.68DD1550 pKa = 3.64LISYY1554 pKa = 8.63GGGWRR1559 pKa = 11.84FQGSWNAGEE1568 pKa = 4.24EE1569 pKa = 4.34VQVIAVEE1576 pKa = 4.09PGKK1579 pKa = 10.35NPKK1582 pKa = 9.42NVQTAPGTFKK1592 pKa = 10.63TPEE1595 pKa = 4.28GEE1597 pKa = 4.21VGAIALDD1604 pKa = 4.22FKK1606 pKa = 10.64PGTSGSPIVNRR1617 pKa = 11.84EE1618 pKa = 3.57GKK1620 pKa = 9.91IVGLYY1625 pKa = 10.43GNGVVTTSGTYY1636 pKa = 10.13VSAIAQAKK1644 pKa = 9.63ASQEE1648 pKa = 4.02GPLPEE1653 pKa = 6.06IEE1655 pKa = 5.06DD1656 pKa = 3.5EE1657 pKa = 4.52VFRR1660 pKa = 11.84KK1661 pKa = 10.12RR1662 pKa = 11.84NLTIMDD1668 pKa = 4.22LHH1670 pKa = 6.68PGSGKK1675 pKa = 7.11TRR1677 pKa = 11.84RR1678 pKa = 11.84YY1679 pKa = 9.3LPAIVRR1685 pKa = 11.84EE1686 pKa = 4.34AIRR1689 pKa = 11.84RR1690 pKa = 11.84NVRR1693 pKa = 11.84TLVLAPTRR1701 pKa = 11.84VVASEE1706 pKa = 3.69MAEE1709 pKa = 4.01ALKK1712 pKa = 10.75GMPIRR1717 pKa = 11.84YY1718 pKa = 6.77QTTAVKK1724 pKa = 10.43SEE1726 pKa = 4.02HH1727 pKa = 5.71TGKK1730 pKa = 10.83EE1731 pKa = 4.07IVDD1734 pKa = 4.09LMCHH1738 pKa = 5.31ATFTMRR1744 pKa = 11.84LLSPVRR1750 pKa = 11.84VPNYY1754 pKa = 10.79NMIIMDD1760 pKa = 4.22EE1761 pKa = 4.12AHH1763 pKa = 6.01FTDD1766 pKa = 4.51PASIAARR1773 pKa = 11.84GYY1775 pKa = 8.52ISTRR1779 pKa = 11.84VGMGEE1784 pKa = 3.54AAAIFMTATPPGSVEE1799 pKa = 5.35AFPQSNAVIQDD1810 pKa = 3.52EE1811 pKa = 4.29EE1812 pKa = 4.85RR1813 pKa = 11.84DD1814 pKa = 3.5IPEE1817 pKa = 4.2RR1818 pKa = 11.84SWNSGYY1824 pKa = 11.2DD1825 pKa = 3.34WITDD1829 pKa = 3.96FPGKK1833 pKa = 7.84TVWFVPSIKK1842 pKa = 10.33SGNDD1846 pKa = 2.71IANCLRR1852 pKa = 11.84KK1853 pKa = 9.55NGKK1856 pKa = 9.33RR1857 pKa = 11.84VVQLSRR1863 pKa = 11.84KK1864 pKa = 7.57TFDD1867 pKa = 2.99TEE1869 pKa = 4.1YY1870 pKa = 11.09QKK1872 pKa = 9.79TKK1874 pKa = 10.86NNDD1877 pKa = 2.44WDD1879 pKa = 4.24YY1880 pKa = 12.01VVTTDD1885 pKa = 4.45ISEE1888 pKa = 3.91MGANFRR1894 pKa = 11.84ADD1896 pKa = 3.41RR1897 pKa = 11.84VIDD1900 pKa = 3.66PRR1902 pKa = 11.84RR1903 pKa = 11.84CLKK1906 pKa = 10.44PVILKK1911 pKa = 10.18DD1912 pKa = 3.38GPEE1915 pKa = 3.91RR1916 pKa = 11.84VILAGPMPVTVASAAQRR1933 pKa = 11.84RR1934 pKa = 11.84GRR1936 pKa = 11.84IGRR1939 pKa = 11.84NQNKK1943 pKa = 10.16EE1944 pKa = 3.51GDD1946 pKa = 3.43QYY1948 pKa = 11.59IYY1950 pKa = 10.15MGQPLNNDD1958 pKa = 3.21EE1959 pKa = 5.49DD1960 pKa = 4.12HH1961 pKa = 6.89AHH1963 pKa = 5.06WTEE1966 pKa = 4.43AKK1968 pKa = 9.72MLLDD1972 pKa = 5.03NINTPEE1978 pKa = 4.5GIIPALFEE1986 pKa = 4.23PEE1988 pKa = 4.14RR1989 pKa = 11.84EE1990 pKa = 3.79KK1991 pKa = 11.15SAAIDD1996 pKa = 3.31GEE1998 pKa = 4.15YY1999 pKa = 10.51RR2000 pKa = 11.84LRR2002 pKa = 11.84GEE2004 pKa = 3.83ARR2006 pKa = 11.84KK2007 pKa = 7.94TFVEE2011 pKa = 3.99LMRR2014 pKa = 11.84RR2015 pKa = 11.84GDD2017 pKa = 3.69LPVWLSYY2024 pKa = 10.64KK2025 pKa = 9.95VASEE2029 pKa = 4.24GFQYY2033 pKa = 11.02SDD2035 pKa = 4.56RR2036 pKa = 11.84RR2037 pKa = 11.84WCFDD2041 pKa = 3.23GEE2043 pKa = 4.36RR2044 pKa = 11.84NNQVLEE2050 pKa = 4.08EE2051 pKa = 4.15NMDD2054 pKa = 3.47VEE2056 pKa = 4.4IWTKK2060 pKa = 9.93EE2061 pKa = 3.93GEE2063 pKa = 4.39RR2064 pKa = 11.84KK2065 pKa = 9.68KK2066 pKa = 10.87LRR2068 pKa = 11.84PRR2070 pKa = 11.84WLDD2073 pKa = 2.83ARR2075 pKa = 11.84TYY2077 pKa = 10.93SDD2079 pKa = 3.77PLALRR2084 pKa = 11.84EE2085 pKa = 4.21FKK2087 pKa = 10.68EE2088 pKa = 4.26FAAGRR2093 pKa = 11.84RR2094 pKa = 11.84SVSGDD2099 pKa = 3.72LILEE2103 pKa = 4.24IGKK2106 pKa = 9.51LPQHH2110 pKa = 6.06LTQRR2114 pKa = 11.84AQNALDD2120 pKa = 3.8NLVMLHH2126 pKa = 6.37NSEE2129 pKa = 4.42QGGKK2133 pKa = 9.83AYY2135 pKa = 10.2RR2136 pKa = 11.84HH2137 pKa = 5.8AMEE2140 pKa = 5.09EE2141 pKa = 4.15LPDD2144 pKa = 4.28TIEE2147 pKa = 3.97TLMLLALIAVLTGGVTLFFLSGRR2170 pKa = 11.84GLGKK2174 pKa = 9.19TSIGLLCVIASSALLWMASVEE2195 pKa = 4.2PHH2197 pKa = 6.88WIAASIILEE2206 pKa = 4.12FFLMVLLIPEE2216 pKa = 5.06PDD2218 pKa = 3.44RR2219 pKa = 11.84QRR2221 pKa = 11.84TPQDD2225 pKa = 2.98NQLAYY2230 pKa = 10.77VVIGLLFMILTAAANEE2246 pKa = 4.06MGLLEE2251 pKa = 4.31TTKK2254 pKa = 10.59KK2255 pKa = 10.79DD2256 pKa = 3.54LGIGHH2261 pKa = 7.65AAAEE2265 pKa = 4.37NHH2267 pKa = 5.7HH2268 pKa = 6.71HH2269 pKa = 7.0AAMLDD2274 pKa = 3.67VDD2276 pKa = 4.71LHH2278 pKa = 6.34PASAWTLYY2286 pKa = 10.76AVATTIITPMMRR2298 pKa = 11.84HH2299 pKa = 5.58TIEE2302 pKa = 3.87NTTANISLTAIANQAAILMGLDD2324 pKa = 3.48KK2325 pKa = 10.85GWPISKK2331 pKa = 9.37MDD2333 pKa = 3.33IGVPLLALGCYY2344 pKa = 9.67SQVNPLTLTAAVFMLVAHH2362 pKa = 6.12YY2363 pKa = 10.42AIIGPGLQAKK2373 pKa = 7.77ATRR2376 pKa = 11.84EE2377 pKa = 4.13AQKK2380 pKa = 9.55RR2381 pKa = 11.84TAAGIMKK2388 pKa = 9.99NPTVDD2393 pKa = 4.06GIVAIDD2399 pKa = 4.75LDD2401 pKa = 4.16PVVYY2405 pKa = 9.93DD2406 pKa = 4.7AKK2408 pKa = 10.89FEE2410 pKa = 4.13KK2411 pKa = 10.53QLGQIMLLILCTSQILLMRR2430 pKa = 11.84TTWALCEE2437 pKa = 4.51SITLATGPLTTLWEE2451 pKa = 4.47GSPGKK2456 pKa = 10.02FWNTTIAVSMANIFRR2471 pKa = 11.84GSYY2474 pKa = 9.71LAGAGLAFSLMKK2486 pKa = 10.64SLGGGRR2492 pKa = 11.84RR2493 pKa = 11.84GTGAQGEE2500 pKa = 4.56TLGEE2504 pKa = 3.74KK2505 pKa = 9.33WKK2507 pKa = 10.64RR2508 pKa = 11.84QLNQLSKK2515 pKa = 11.28SEE2517 pKa = 3.91FNTYY2521 pKa = 9.24KK2522 pKa = 10.2RR2523 pKa = 11.84SGIIEE2528 pKa = 4.01VDD2530 pKa = 2.94RR2531 pKa = 11.84SEE2533 pKa = 4.56AKK2535 pKa = 10.18EE2536 pKa = 3.73GLKK2539 pKa = 10.45RR2540 pKa = 11.84GEE2542 pKa = 4.16PTKK2545 pKa = 10.51HH2546 pKa = 5.05AVSRR2550 pKa = 11.84GTAKK2554 pKa = 10.44LRR2556 pKa = 11.84WFVEE2560 pKa = 4.14RR2561 pKa = 11.84NLVKK2565 pKa = 10.73PEE2567 pKa = 3.92GKK2569 pKa = 10.64VIDD2572 pKa = 4.49LGCGRR2577 pKa = 11.84GGWSYY2582 pKa = 11.91YY2583 pKa = 10.16CAGLKK2588 pKa = 10.18KK2589 pKa = 8.7VTEE2592 pKa = 4.19VKK2594 pKa = 10.61GYY2596 pKa = 8.05TKK2598 pKa = 10.49GGPGHH2603 pKa = 6.42EE2604 pKa = 4.59EE2605 pKa = 4.67PIPMATYY2612 pKa = 9.68GWNLVKK2618 pKa = 10.47LYY2620 pKa = 10.43SGKK2623 pKa = 10.33DD2624 pKa = 3.3VFFTPPEE2631 pKa = 4.11KK2632 pKa = 10.45CDD2634 pKa = 3.7TLLCDD2639 pKa = 4.45IGEE2642 pKa = 4.31SSPNPTIEE2650 pKa = 3.73EE2651 pKa = 4.22GRR2653 pKa = 11.84TLRR2656 pKa = 11.84VLKK2659 pKa = 10.05MVEE2662 pKa = 3.2PWLRR2666 pKa = 11.84GNQFCIKK2673 pKa = 9.83ILNPYY2678 pKa = 8.29MPSVVEE2684 pKa = 4.26TLEE2687 pKa = 3.79QMQRR2691 pKa = 11.84KK2692 pKa = 8.22HH2693 pKa = 7.41GGMLVRR2699 pKa = 11.84NPLSRR2704 pKa = 11.84NSTHH2708 pKa = 4.89EE2709 pKa = 4.41MYY2711 pKa = 9.64WVSCGTGNIVSAVNMTSRR2729 pKa = 11.84MLLNRR2734 pKa = 11.84FTMAHH2739 pKa = 6.78RR2740 pKa = 11.84KK2741 pKa = 6.35PTYY2744 pKa = 10.1EE2745 pKa = 4.03RR2746 pKa = 11.84DD2747 pKa = 3.15VDD2749 pKa = 4.17LGAGTRR2755 pKa = 11.84HH2756 pKa = 5.3VAVEE2760 pKa = 4.15PEE2762 pKa = 4.22VANLDD2767 pKa = 3.79IIGQRR2772 pKa = 11.84IEE2774 pKa = 4.15NIKK2777 pKa = 10.58NGHH2780 pKa = 6.27KK2781 pKa = 9.46STWHH2785 pKa = 5.69YY2786 pKa = 11.74DD2787 pKa = 3.03EE2788 pKa = 6.14DD2789 pKa = 4.07NPYY2792 pKa = 8.4KK2793 pKa = 9.24TWAYY2797 pKa = 9.37HH2798 pKa = 5.42GSYY2801 pKa = 9.2EE2802 pKa = 4.27VKK2804 pKa = 10.27PSGSASSMVNGVVRR2818 pKa = 11.84LLTKK2822 pKa = 9.75PWDD2825 pKa = 4.11VIPMVTQIAMTDD2837 pKa = 3.36TTPFGQQRR2845 pKa = 11.84VFKK2848 pKa = 9.7EE2849 pKa = 4.16KK2850 pKa = 10.85VDD2852 pKa = 3.51TRR2854 pKa = 11.84TPKK2857 pKa = 10.56AKK2859 pKa = 10.27RR2860 pKa = 11.84GTAQIMEE2867 pKa = 4.41VTARR2871 pKa = 11.84WLWGFLSRR2879 pKa = 11.84NKK2881 pKa = 10.08KK2882 pKa = 9.69PRR2884 pKa = 11.84ICTRR2888 pKa = 11.84EE2889 pKa = 3.52EE2890 pKa = 3.56FTRR2893 pKa = 11.84KK2894 pKa = 9.1VRR2896 pKa = 11.84SNAAIGAVFVDD2907 pKa = 3.83EE2908 pKa = 4.62NQWNSAKK2915 pKa = 10.46EE2916 pKa = 3.83AVEE2919 pKa = 5.68DD2920 pKa = 3.66EE2921 pKa = 4.54RR2922 pKa = 11.84FWDD2925 pKa = 3.74LVHH2928 pKa = 7.7RR2929 pKa = 11.84EE2930 pKa = 4.11RR2931 pKa = 11.84EE2932 pKa = 3.85LHH2934 pKa = 5.9KK2935 pKa = 10.5QGKK2938 pKa = 8.89CATCVYY2944 pKa = 11.26NMMGKK2949 pKa = 9.2RR2950 pKa = 11.84EE2951 pKa = 4.01KK2952 pKa = 10.78KK2953 pKa = 10.17LGEE2956 pKa = 3.75FGKK2959 pKa = 10.75AKK2961 pKa = 10.05GSRR2964 pKa = 11.84AIWYY2968 pKa = 7.23MWLGARR2974 pKa = 11.84FLEE2977 pKa = 4.92FEE2979 pKa = 4.47ALGFMNEE2986 pKa = 4.06DD2987 pKa = 2.72HH2988 pKa = 6.43WFSRR2992 pKa = 11.84EE2993 pKa = 3.69NSLSGVEE3000 pKa = 4.56GEE3002 pKa = 4.68GLHH3005 pKa = 5.91KK3006 pKa = 10.51LGYY3009 pKa = 9.24ILRR3012 pKa = 11.84DD3013 pKa = 3.12ISKK3016 pKa = 10.14IPGGNMYY3023 pKa = 10.95ADD3025 pKa = 4.59DD3026 pKa = 3.74TAGWDD3031 pKa = 3.53TRR3033 pKa = 11.84ITEE3036 pKa = 5.16DD3037 pKa = 5.0DD3038 pKa = 4.04LQNEE3042 pKa = 4.31AKK3044 pKa = 8.93ITDD3047 pKa = 3.3IMEE3050 pKa = 4.53PEE3052 pKa = 4.12HH3053 pKa = 6.91ALLATSIFKK3062 pKa = 8.87LTYY3065 pKa = 7.31QNKK3068 pKa = 7.62VVRR3071 pKa = 11.84VQRR3074 pKa = 11.84PAKK3077 pKa = 9.71NGTVMDD3083 pKa = 4.68VISRR3087 pKa = 11.84RR3088 pKa = 11.84DD3089 pKa = 3.28QRR3091 pKa = 11.84GSGQVGTYY3099 pKa = 10.37GLNTFTNMEE3108 pKa = 4.08AQLIRR3113 pKa = 11.84QMEE3116 pKa = 4.39SEE3118 pKa = 5.04GIFSPSEE3125 pKa = 3.93LEE3127 pKa = 4.24TPNLAEE3133 pKa = 5.96RR3134 pKa = 11.84VLDD3137 pKa = 3.47WLKK3140 pKa = 10.93KK3141 pKa = 10.07HH3142 pKa = 4.62GTEE3145 pKa = 3.65RR3146 pKa = 11.84LKK3148 pKa = 11.21RR3149 pKa = 11.84MAISGDD3155 pKa = 3.62DD3156 pKa = 3.78CVVKK3160 pKa = 10.53PIDD3163 pKa = 4.51DD3164 pKa = 4.05RR3165 pKa = 11.84FATALTALNDD3175 pKa = 3.51MGKK3178 pKa = 9.4VRR3180 pKa = 11.84KK3181 pKa = 9.54DD3182 pKa = 3.03IPQWEE3187 pKa = 4.28PSKK3190 pKa = 11.09GWNDD3194 pKa = 3.14WQQVPFCSHH3203 pKa = 7.0HH3204 pKa = 4.87FHH3206 pKa = 6.36QLIMKK3211 pKa = 9.27DD3212 pKa = 2.94GRR3214 pKa = 11.84EE3215 pKa = 3.84IVVPCRR3221 pKa = 11.84NQDD3224 pKa = 3.56EE3225 pKa = 4.67LVGRR3229 pKa = 11.84ARR3231 pKa = 11.84VSQGAGWSLRR3241 pKa = 11.84EE3242 pKa = 3.93TACLGKK3248 pKa = 10.26SYY3250 pKa = 11.13AQMWQLMYY3258 pKa = 9.12FHH3260 pKa = 7.15RR3261 pKa = 11.84RR3262 pKa = 11.84DD3263 pKa = 3.23LRR3265 pKa = 11.84LAANAICSAVPVDD3278 pKa = 3.81WVPTSRR3284 pKa = 11.84TTWSIHH3290 pKa = 5.75AHH3292 pKa = 5.0HH3293 pKa = 6.22QWMTTEE3299 pKa = 4.99DD3300 pKa = 4.28MLSVWNRR3307 pKa = 11.84VWIEE3311 pKa = 3.77EE3312 pKa = 4.24NPWMEE3317 pKa = 4.8DD3318 pKa = 3.06KK3319 pKa = 10.48THH3321 pKa = 5.48VSSWEE3326 pKa = 3.82DD3327 pKa = 3.19VPYY3330 pKa = 10.56LGKK3333 pKa = 10.38RR3334 pKa = 11.84EE3335 pKa = 4.05DD3336 pKa = 3.46RR3337 pKa = 11.84WCGSLIGLTARR3348 pKa = 11.84ATWATNIQVAINQVRR3363 pKa = 11.84RR3364 pKa = 11.84LIGNEE3369 pKa = 3.58NYY3371 pKa = 10.61LDD3373 pKa = 3.95FMTSMKK3379 pKa = 10.28RR3380 pKa = 11.84FKK3382 pKa = 11.01NEE3384 pKa = 3.71SDD3386 pKa = 3.59PEE3388 pKa = 4.2GALWW3392 pKa = 3.93

Molecular weight:
378.7 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

3392

3392

3392

3392.0

378.7

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.075 ± 0.0

1.739 ± 0.0

4.245 ± 0.0

6.456 ± 0.0

3.184 ± 0.0

8.284 ± 0.0

2.123 ± 0.0

5.778 ± 0.0

6.044 ± 0.0

9.346 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.715 ± 0.0

3.744 ± 0.0

4.127 ± 0.0

3.213 ± 0.0

5.66 ± 0.0

5.985 ± 0.0

7.636 ± 0.0

6.692 ± 0.0

2.83 ± 0.0

2.123 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski