Amino acid dipepetide frequency for Narcissus common latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.315AlaAla: 8.315 ± 2.128
1.446AlaCys: 1.446 ± 0.726
3.977AlaAsp: 3.977 ± 1.526
2.531AlaGlu: 2.531 ± 0.964
2.531AlaPhe: 2.531 ± 1.092
3.615AlaGly: 3.615 ± 1.553
2.531AlaHis: 2.531 ± 0.642
3.977AlaIle: 3.977 ± 1.509
5.785AlaLys: 5.785 ± 3.189
10.484AlaLeu: 10.484 ± 1.842
1.808AlaMet: 1.808 ± 0.691
2.892AlaAsn: 2.892 ± 1.428
3.615AlaPro: 3.615 ± 0.993
4.7AlaGln: 4.7 ± 1.492
2.531AlaArg: 2.531 ± 1.226
6.146AlaSer: 6.146 ± 1.279
5.061AlaThr: 5.061 ± 1.094
5.423AlaVal: 5.423 ± 4.121
0.723AlaTrp: 0.723 ± 0.399
1.808AlaTyr: 1.808 ± 1.829
0.0AlaXaa: 0.0 ± 0.0
Cys
1.808CysAla: 1.808 ± 0.997
0.362CysCys: 0.362 ± 0.199
0.723CysAsp: 0.723 ± 1.516
1.085CysGlu: 1.085 ± 0.598
2.892CysPhe: 2.892 ± 1.129
1.808CysGly: 1.808 ± 0.957
0.362CysHis: 0.362 ± 1.254
1.446CysIle: 1.446 ± 0.797
2.169CysLys: 2.169 ± 0.912
2.169CysLeu: 2.169 ± 4.277
0.362CysMet: 0.362 ± 0.199
0.362CysAsn: 0.362 ± 0.199
0.723CysPro: 0.723 ± 0.731
1.085CysGln: 1.085 ± 0.598
1.808CysArg: 1.808 ± 0.987
1.808CysSer: 1.808 ± 0.997
2.531CysThr: 2.531 ± 1.395
2.892CysVal: 2.892 ± 1.567
0.0CysTrp: 0.0 ± 0.0
1.446CysTyr: 1.446 ± 1.277
0.0CysXaa: 0.0 ± 0.0
Asp
2.892AspAla: 2.892 ± 1.781
1.808AspCys: 1.808 ± 0.691
1.808AspAsp: 1.808 ± 1.2
3.977AspGlu: 3.977 ± 1.141
2.531AspPhe: 2.531 ± 1.046
4.338AspGly: 4.338 ± 1.26
0.723AspHis: 0.723 ± 1.033
1.808AspIle: 1.808 ± 0.691
1.446AspLys: 1.446 ± 0.609
3.615AspLeu: 3.615 ± 0.98
1.085AspMet: 1.085 ± 1.344
1.808AspAsn: 1.808 ± 1.099
2.531AspPro: 2.531 ± 1.646
0.362AspGln: 0.362 ± 0.199
2.169AspArg: 2.169 ± 1.696
2.531AspSer: 2.531 ± 1.607
2.531AspThr: 2.531 ± 1.092
2.892AspVal: 2.892 ± 1.451
1.446AspTrp: 1.446 ± 0.609
2.169AspTyr: 2.169 ± 0.624
0.0AspXaa: 0.0 ± 0.0
Glu
5.785GluAla: 5.785 ± 1.543
0.362GluCys: 0.362 ± 0.199
2.531GluAsp: 2.531 ± 1.092
5.423GluGlu: 5.423 ± 2.404
2.531GluPhe: 2.531 ± 1.171
3.615GluGly: 3.615 ± 1.77
2.169GluHis: 2.169 ± 0.915
2.169GluIle: 2.169 ± 1.401
1.808GluLys: 1.808 ± 0.691
6.508GluLeu: 6.508 ± 1.754
1.808GluMet: 1.808 ± 0.997
3.254GluAsn: 3.254 ± 0.836
2.169GluPro: 2.169 ± 0.915
1.808GluGln: 1.808 ± 1.2
4.338GluArg: 4.338 ± 1.906
3.254GluSer: 3.254 ± 1.489
1.446GluThr: 1.446 ± 0.609
5.423GluVal: 5.423 ± 2.421
0.723GluTrp: 0.723 ± 0.629
1.808GluTyr: 1.808 ± 0.801
0.0GluXaa: 0.0 ± 0.0
Phe
3.977PheAla: 3.977 ± 1.038
1.446PheCys: 1.446 ± 0.609
4.338PheAsp: 4.338 ± 1.117
6.508PheGlu: 6.508 ± 1.105
1.808PhePhe: 1.808 ± 1.147
2.892PheGly: 2.892 ± 1.523
0.362PheHis: 0.362 ± 0.199
2.892PheIle: 2.892 ± 1.058
2.169PheLys: 2.169 ± 1.196
7.231PheLeu: 7.231 ± 2.969
0.723PheMet: 0.723 ± 0.399
1.446PheAsn: 1.446 ± 0.797
0.362PhePro: 0.362 ± 0.199
1.085PheGln: 1.085 ± 1.449
2.169PheArg: 2.169 ± 1.196
3.977PheSer: 3.977 ± 1.67
2.892PheThr: 2.892 ± 1.217
4.338PheVal: 4.338 ± 1.699
0.362PheTrp: 0.362 ± 0.199
1.085PheTyr: 1.085 ± 0.598
0.0PheXaa: 0.0 ± 0.0
Gly
5.423GlyAla: 5.423 ± 1.475
1.808GlyCys: 1.808 ± 1.313
3.615GlyAsp: 3.615 ± 2.208
2.169GlyGlu: 2.169 ± 1.193
2.169GlyPhe: 2.169 ± 1.173
3.977GlyGly: 3.977 ± 2.758
1.085GlyHis: 1.085 ± 0.968
2.169GlyIle: 2.169 ± 1.51
3.977GlyLys: 3.977 ± 2.115
7.954GlyLeu: 7.954 ± 1.749
0.362GlyMet: 0.362 ± 0.199
1.808GlyAsn: 1.808 ± 1.313
1.085GlyPro: 1.085 ± 0.586
1.085GlyGln: 1.085 ± 0.598
5.061GlyArg: 5.061 ± 2.144
4.338GlySer: 4.338 ± 1.117
3.254GlyThr: 3.254 ± 1.889
3.977GlyVal: 3.977 ± 2.763
1.446GlyTrp: 1.446 ± 0.726
1.446GlyTyr: 1.446 ± 0.797
0.0GlyXaa: 0.0 ± 0.0
His
1.446HisAla: 1.446 ± 0.797
1.085HisCys: 1.085 ± 1.53
1.085HisAsp: 1.085 ± 0.586
2.169HisGlu: 2.169 ± 0.815
0.362HisPhe: 0.362 ± 0.199
1.446HisGly: 1.446 ± 0.942
1.446HisHis: 1.446 ± 1.277
1.808HisIle: 1.808 ± 2.257
1.446HisLys: 1.446 ± 0.609
4.7HisLeu: 4.7 ± 2.591
0.362HisMet: 0.362 ± 1.041
2.169HisAsn: 2.169 ± 0.912
1.446HisPro: 1.446 ± 0.797
0.0HisGln: 0.0 ± 0.0
1.808HisArg: 1.808 ± 1.191
4.338HisSer: 4.338 ± 2.372
0.723HisThr: 0.723 ± 0.399
0.723HisVal: 0.723 ± 0.399
0.362HisTrp: 0.362 ± 0.199
0.362HisTyr: 0.362 ± 0.199
0.0HisXaa: 0.0 ± 0.0
Ile
4.338IleAla: 4.338 ± 4.202
2.169IleCys: 2.169 ± 0.915
1.085IleAsp: 1.085 ± 0.598
4.338IleGlu: 4.338 ± 0.798
2.169IlePhe: 2.169 ± 1.196
2.892IleGly: 2.892 ± 1.469
1.446IleHis: 1.446 ± 0.726
1.808IleIle: 1.808 ± 1.992
2.892IleLys: 2.892 ± 0.886
3.254IleLeu: 3.254 ± 1.599
1.808IleMet: 1.808 ± 0.997
1.446IleAsn: 1.446 ± 0.797
2.169IlePro: 2.169 ± 1.147
1.446IleGln: 1.446 ± 1.583
3.254IleArg: 3.254 ± 1.418
2.169IleSer: 2.169 ± 1.937
2.169IleThr: 2.169 ± 1.261
4.338IleVal: 4.338 ± 1.465
0.362IleTrp: 0.362 ± 1.13
2.892IleTyr: 2.892 ± 1.214
0.0IleXaa: 0.0 ± 0.0
Lys
3.977LysAla: 3.977 ± 0.738
0.362LysCys: 0.362 ± 0.199
1.808LysAsp: 1.808 ± 1.97
2.531LysGlu: 2.531 ± 1.395
2.892LysPhe: 2.892 ± 1.129
2.531LysGly: 2.531 ± 1.395
0.362LysHis: 0.362 ± 0.199
3.254LysIle: 3.254 ± 1.304
2.531LysLys: 2.531 ± 1.179
7.592LysLeu: 7.592 ± 1.35
0.723LysMet: 0.723 ± 0.399
2.531LysAsn: 2.531 ± 0.984
2.892LysPro: 2.892 ± 1.178
2.892LysGln: 2.892 ± 1.129
2.531LysArg: 2.531 ± 1.395
3.615LysSer: 3.615 ± 1.241
3.254LysThr: 3.254 ± 1.378
3.254LysVal: 3.254 ± 1.447
0.723LysTrp: 0.723 ± 0.731
2.892LysTyr: 2.892 ± 1.058
0.0LysXaa: 0.0 ± 0.0
Leu
8.677LeuAla: 8.677 ± 0.942
2.892LeuCys: 2.892 ± 1.21
5.423LeuAsp: 5.423 ± 0.858
6.146LeuGlu: 6.146 ± 1.743
5.061LeuPhe: 5.061 ± 1.674
6.508LeuGly: 6.508 ± 2.17
1.808LeuHis: 1.808 ± 0.801
4.7LeuIle: 4.7 ± 1.86
7.231LeuLys: 7.231 ± 1.781
10.123LeuLeu: 10.123 ± 4.323
0.723LeuMet: 0.723 ± 0.951
5.061LeuAsn: 5.061 ± 0.81
5.061LeuPro: 5.061 ± 1.938
2.169LeuGln: 2.169 ± 1.196
7.231LeuArg: 7.231 ± 2.458
7.592LeuSer: 7.592 ± 2.718
8.677LeuThr: 8.677 ± 2.665
6.146LeuVal: 6.146 ± 4.237
1.085LeuTrp: 1.085 ± 1.11
2.169LeuTyr: 2.169 ± 0.912
0.0LeuXaa: 0.0 ± 0.0
Met
2.531MetAla: 2.531 ± 0.964
0.723MetCys: 0.723 ± 0.399
1.446MetAsp: 1.446 ± 0.726
0.723MetGlu: 0.723 ± 0.399
0.362MetPhe: 0.362 ± 0.199
0.723MetGly: 0.723 ± 0.629
1.085MetHis: 1.085 ± 2.414
0.362MetIle: 0.362 ± 0.199
0.362MetLys: 0.362 ± 0.199
1.808MetLeu: 1.808 ± 1.255
0.362MetMet: 0.362 ± 0.726
1.085MetAsn: 1.085 ± 0.598
2.531MetPro: 2.531 ± 1.101
0.362MetGln: 0.362 ± 0.199
2.169MetArg: 2.169 ± 1.173
1.085MetSer: 1.085 ± 0.586
0.0MetThr: 0.0 ± 0.0
0.362MetVal: 0.362 ± 0.199
0.0MetTrp: 0.0 ± 0.0
0.723MetTyr: 0.723 ± 1.167
0.0MetXaa: 0.0 ± 0.0
Asn
3.615AsnAla: 3.615 ± 0.993
1.808AsnCys: 1.808 ± 0.997
1.446AsnAsp: 1.446 ± 0.726
1.808AsnGlu: 1.808 ± 1.099
3.615AsnPhe: 3.615 ± 1.198
0.723AsnGly: 0.723 ± 0.629
0.723AsnHis: 0.723 ± 0.399
1.808AsnIle: 1.808 ± 2.441
2.892AsnLys: 2.892 ± 0.718
3.615AsnLeu: 3.615 ± 1.313
1.446AsnMet: 1.446 ± 0.609
1.808AsnAsn: 1.808 ± 0.691
0.362AsnPro: 0.362 ± 0.726
2.169AsnGln: 2.169 ± 1.454
3.254AsnArg: 3.254 ± 1.734
4.7AsnSer: 4.7 ± 1.716
1.085AsnThr: 1.085 ± 1.337
1.808AsnVal: 1.808 ± 0.997
0.723AsnTrp: 0.723 ± 0.399
2.531AsnTyr: 2.531 ± 1.179
0.0AsnXaa: 0.0 ± 0.0
Pro
3.615ProAla: 3.615 ± 1.511
1.085ProCys: 1.085 ± 0.968
3.254ProAsp: 3.254 ± 1.304
2.892ProGlu: 2.892 ± 1.54
0.362ProPhe: 0.362 ± 0.199
2.892ProGly: 2.892 ± 1.567
1.808ProHis: 1.808 ± 0.957
2.892ProIle: 2.892 ± 1.451
0.723ProLys: 0.723 ± 0.399
2.531ProLeu: 2.531 ± 1.932
1.085ProMet: 1.085 ± 1.328
1.085ProAsn: 1.085 ± 0.7
3.615ProPro: 3.615 ± 1.288
1.808ProGln: 1.808 ± 0.997
3.977ProArg: 3.977 ± 1.688
2.169ProSer: 2.169 ± 2.947
3.977ProThr: 3.977 ± 1.526
2.892ProVal: 2.892 ± 0.983
1.085ProTrp: 1.085 ± 0.968
2.892ProTyr: 2.892 ± 1.129
0.0ProXaa: 0.0 ± 0.0
Gln
1.446GlnAla: 1.446 ± 0.609
1.446GlnCys: 1.446 ± 0.726
0.362GlnAsp: 0.362 ± 0.199
1.446GlnGlu: 1.446 ± 0.797
2.169GlnPhe: 2.169 ± 1.196
1.085GlnGly: 1.085 ± 1.493
0.723GlnHis: 0.723 ± 0.629
1.808GlnIle: 1.808 ± 0.801
1.808GlnLys: 1.808 ± 1.2
4.338GlnLeu: 4.338 ± 2.392
0.0GlnMet: 0.0 ± 0.0
0.723GlnAsn: 0.723 ± 0.399
2.531GlnPro: 2.531 ± 2.14
1.446GlnGln: 1.446 ± 0.797
1.446GlnArg: 1.446 ± 1.453
2.892GlnSer: 2.892 ± 1.595
1.085GlnThr: 1.085 ± 0.586
2.892GlnVal: 2.892 ± 1.022
0.723GlnTrp: 0.723 ± 0.399
1.085GlnTyr: 1.085 ± 1.11
0.0GlnXaa: 0.0 ± 0.0
Arg
6.146ArgAla: 6.146 ± 1.895
2.531ArgCys: 2.531 ± 4.378
2.169ArgAsp: 2.169 ± 3.099
4.338ArgGlu: 4.338 ± 1.893
5.061ArgPhe: 5.061 ± 1.403
2.531ArgGly: 2.531 ± 1.523
2.169ArgHis: 2.169 ± 0.915
1.446ArgIle: 1.446 ± 1.257
2.531ArgLys: 2.531 ± 0.964
5.423ArgLeu: 5.423 ± 1.332
2.169ArgMet: 2.169 ± 0.824
2.892ArgAsn: 2.892 ± 1.781
2.531ArgPro: 2.531 ± 2.992
1.085ArgGln: 1.085 ± 0.598
5.423ArgArg: 5.423 ± 3.527
3.254ArgSer: 3.254 ± 1.794
2.531ArgThr: 2.531 ± 1.109
3.615ArgVal: 3.615 ± 1.613
1.085ArgTrp: 1.085 ± 0.7
2.169ArgTyr: 2.169 ± 1.196
0.0ArgXaa: 0.0 ± 0.0
Ser
5.061SerAla: 5.061 ± 1.351
2.169SerCys: 2.169 ± 1.193
3.977SerAsp: 3.977 ± 1.783
2.892SerGlu: 2.892 ± 0.718
4.338SerPhe: 4.338 ± 1.313
6.146SerGly: 6.146 ± 1.361
2.892SerHis: 2.892 ± 1.595
3.615SerIle: 3.615 ± 1.028
5.061SerLys: 5.061 ± 1.839
5.785SerLeu: 5.785 ± 1.738
1.085SerMet: 1.085 ± 0.932
2.531SerAsn: 2.531 ± 1.342
3.254SerPro: 3.254 ± 1.107
1.808SerGln: 1.808 ± 0.997
2.531SerArg: 2.531 ± 3.954
6.869SerSer: 6.869 ± 1.99
6.508SerThr: 6.508 ± 1.902
3.977SerVal: 3.977 ± 2.435
0.0SerTrp: 0.0 ± 0.0
2.169SerTyr: 2.169 ± 2.602
0.0SerXaa: 0.0 ± 0.0
Thr
5.423ThrAla: 5.423 ± 2.385
0.362ThrCys: 0.362 ± 1.254
1.085ThrAsp: 1.085 ± 0.586
4.338ThrGlu: 4.338 ± 1.376
5.423ThrPhe: 5.423 ± 2.261
4.7ThrGly: 4.7 ± 2.527
3.254ThrHis: 3.254 ± 1.189
2.531ThrIle: 2.531 ± 0.964
3.615ThrLys: 3.615 ± 3.469
7.231ThrLeu: 7.231 ± 1.91
0.362ThrMet: 0.362 ± 0.19
1.085ThrAsn: 1.085 ± 0.586
2.531ThrPro: 2.531 ± 1.665
1.085ThrGln: 1.085 ± 0.598
2.169ThrArg: 2.169 ± 1.224
4.7ThrSer: 4.7 ± 2.933
3.254ThrThr: 3.254 ± 3.476
3.254ThrVal: 3.254 ± 0.988
1.085ThrTrp: 1.085 ± 1.223
1.446ThrTyr: 1.446 ± 0.726
0.0ThrXaa: 0.0 ± 0.0
Val
3.615ValAla: 3.615 ± 1.503
2.531ValCys: 2.531 ± 0.877
1.808ValAsp: 1.808 ± 1.165
2.531ValGlu: 2.531 ± 0.642
3.615ValPhe: 3.615 ± 1.77
3.615ValGly: 3.615 ± 2.23
3.254ValHis: 3.254 ± 1.378
3.977ValIle: 3.977 ± 1.67
1.808ValLys: 1.808 ± 0.801
6.869ValLeu: 6.869 ± 1.494
0.362ValMet: 0.362 ± 1.254
2.892ValAsn: 2.892 ± 1.451
3.615ValPro: 3.615 ± 1.337
2.892ValGln: 2.892 ± 1.022
4.7ValArg: 4.7 ± 1.697
5.061ValSer: 5.061 ± 1.929
4.7ValThr: 4.7 ± 4.139
3.615ValVal: 3.615 ± 4.019
0.362ValTrp: 0.362 ± 0.199
2.169ValTyr: 2.169 ± 1.51
0.0ValXaa: 0.0 ± 0.0
Trp
0.723TrpAla: 0.723 ± 1.37
0.723TrpCys: 0.723 ± 0.399
0.0TrpAsp: 0.0 ± 0.0
0.362TrpGlu: 0.362 ± 0.199
0.723TrpPhe: 0.723 ± 0.399
0.0TrpGly: 0.0 ± 0.0
0.723TrpHis: 0.723 ± 0.399
0.723TrpIle: 0.723 ± 1.044
0.362TrpLys: 0.362 ± 0.199
1.808TrpLeu: 1.808 ± 0.957
0.0TrpMet: 0.0 ± 0.0
1.446TrpAsn: 1.446 ± 1.093
1.446TrpPro: 1.446 ± 1.277
0.362TrpGln: 0.362 ± 0.81
0.723TrpArg: 0.723 ± 0.399
0.362TrpSer: 0.362 ± 0.199
0.0TrpThr: 0.0 ± 0.0
1.446TrpVal: 1.446 ± 0.797
0.0TrpTrp: 0.0 ± 0.0
0.723TrpTyr: 0.723 ± 0.399
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.085TyrAla: 1.085 ± 1.371
0.723TyrCys: 0.723 ± 0.399
2.531TyrAsp: 2.531 ± 1.109
0.723TyrGlu: 0.723 ± 0.399
1.446TyrPhe: 1.446 ± 0.726
2.169TyrGly: 2.169 ± 0.624
0.362TyrHis: 0.362 ± 0.199
3.254TyrIle: 3.254 ± 1.895
2.531TyrLys: 2.531 ± 1.395
1.808TyrLeu: 1.808 ± 0.997
1.808TyrMet: 1.808 ± 0.691
3.615TyrAsn: 3.615 ± 3.746
2.169TyrPro: 2.169 ± 1.196
1.808TyrGln: 1.808 ± 0.801
1.808TyrArg: 1.808 ± 1.581
1.808TyrSer: 1.808 ± 0.801
3.254TyrThr: 3.254 ± 2.829
0.723TyrVal: 0.723 ± 0.629
0.362TyrTrp: 0.362 ± 0.199
1.085TyrTyr: 1.085 ± 0.598
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2767 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski