Streptococcus mutans serotype c (strain ATCC 700610 / UA159)

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus mutans

Average proteome isoelectric point is 6.72

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1953 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q8DWL2|Q8DWL2_STRMU Uncharacterized protein OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=SMU_33 PE=4 SV=1
MM1 pKa = 7.28MEE3 pKa = 4.11EE4 pKa = 3.92FDD6 pKa = 6.37DD7 pKa = 4.73VFEE10 pKa = 6.59DD11 pKa = 6.17DD12 pKa = 3.44ITTLTFTYY20 pKa = 10.17ADD22 pKa = 3.22EE23 pKa = 4.38VVIPEE28 pKa = 4.2IPDD31 pKa = 3.24AEE33 pKa = 4.89GIHH36 pKa = 6.64IVEE39 pKa = 4.09ITNNRR44 pKa = 11.84LVIEE48 pKa = 4.26HH49 pKa = 6.45TRR51 pKa = 11.84DD52 pKa = 3.28DD53 pKa = 4.37DD54 pKa = 3.74EE55 pKa = 4.99VYY57 pKa = 10.51EE58 pKa = 4.21YY59 pKa = 10.56IEE61 pKa = 4.48SCGLTSRR68 pKa = 11.84PIKK71 pKa = 10.5LSIEE75 pKa = 3.96FCVYY79 pKa = 10.59EE80 pKa = 4.89DD81 pKa = 3.97PEE83 pKa = 4.3EE84 pKa = 4.19EE85 pKa = 4.2NFF87 pKa = 4.05

Molecular weight: 10.2 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q8DVX9|SYE_STRMU Glutamate--tRNA ligase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gltX PE=3 SV=1
MM1 pKa = 7.45KK2 pKa = 9.59RR3 pKa = 11.84TFQPSKK9 pKa = 9.73IRR11 pKa = 11.84RR12 pKa = 11.84QRR14 pKa = 11.84KK15 pKa = 7.52HH16 pKa = 5.2GFRR19 pKa = 11.84HH20 pKa = 6.39RR21 pKa = 11.84MSTKK25 pKa = 9.02NGRR28 pKa = 11.84RR29 pKa = 11.84VLAARR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84KK37 pKa = 8.81GRR39 pKa = 11.84KK40 pKa = 8.75VLSAA44 pKa = 4.05

Molecular weight: 5.35 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1953

0

1953

578564

25

2724

296.2

33.3

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.474 ± 0.063

0.572 ± 0.014

5.662 ± 0.046

6.387 ± 0.058

4.759 ± 0.047

6.268 ± 0.049

1.957 ± 0.022

7.744 ± 0.053

7.407 ± 0.049

10.129 ± 0.07

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.425 ± 0.025

4.852 ± 0.048

3.156 ± 0.027

4.076 ± 0.04

3.909 ± 0.037

6.283 ± 0.044

5.624 ± 0.041

6.599 ± 0.047

0.872 ± 0.018

3.846 ± 0.039
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski