Amino acid dipepetide frequency for Tessaracoccus bendigoensis DSM 12906

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.759AlaAla: 16.759 ± 0.174	0.954AlaCys: 0.954 ± 0.034	7.804AlaAsp: 7.804 ± 0.094	7.883AlaGlu: 7.883 ± 0.099	3.629AlaPhe: 3.629 ± 0.056	10.682AlaGly: 10.682 ± 0.114	2.309AlaHis: 2.309 ± 0.048	5.077AlaIle: 5.077 ± 0.065	3.002AlaLys: 3.002 ± 0.065	12.755AlaLeu: 12.755 ± 0.132	2.766AlaMet: 2.766 ± 0.054	2.564AlaAsn: 2.564 ± 0.05	5.607AlaPro: 5.607 ± 0.08	3.774AlaGln: 3.774 ± 0.056	8.38AlaArg: 8.38 ± 0.102	7.008AlaSer: 7.008 ± 0.084	7.674AlaThr: 7.674 ± 0.11	10.573AlaVal: 10.573 ± 0.109	2.01AlaTrp: 2.01 ± 0.04	2.271AlaTyr: 2.271 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.786CysAla: 0.786 ± 0.023	0.088CysCys: 0.088 ± 0.01	0.463CysAsp: 0.463 ± 0.02	0.383CysGlu: 0.383 ± 0.017	0.211CysPhe: 0.211 ± 0.014	0.787CysGly: 0.787 ± 0.032	0.17CysHis: 0.17 ± 0.014	0.248CysIle: 0.248 ± 0.015	0.096CysLys: 0.096 ± 0.008	0.69CysLeu: 0.69 ± 0.021	0.126CysMet: 0.126 ± 0.01	0.153CysAsn: 0.153 ± 0.011	0.449CysPro: 0.449 ± 0.025	0.182CysGln: 0.182 ± 0.012	0.592CysArg: 0.592 ± 0.024	0.416CysSer: 0.416 ± 0.018	0.407CysThr: 0.407 ± 0.021	0.575CysVal: 0.575 ± 0.022	0.102CysTrp: 0.102 ± 0.009	0.172CysTyr: 0.172 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.552AspAla: 7.552 ± 0.093	0.343AspCys: 0.343 ± 0.018	4.149AspAsp: 4.149 ± 0.066	4.31AspGlu: 4.31 ± 0.064	1.775AspPhe: 1.775 ± 0.04	6.38AspGly: 6.38 ± 0.087	1.229AspHis: 1.229 ± 0.034	2.246AspIle: 2.246 ± 0.043	1.234AspLys: 1.234 ± 0.028	6.71AspLeu: 6.71 ± 0.073	0.921AspMet: 0.921 ± 0.03	1.088AspAsn: 1.088 ± 0.029	4.334AspPro: 4.334 ± 0.06	1.95AspGln: 1.95 ± 0.039	4.218AspArg: 4.218 ± 0.067	2.86AspSer: 2.86 ± 0.051	2.962AspThr: 2.962 ± 0.055	5.036AspVal: 5.036 ± 0.069	1.013AspTrp: 1.013 ± 0.031	1.271AspTyr: 1.271 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.665GluAla: 7.665 ± 0.087	0.364GluCys: 0.364 ± 0.017	2.874GluAsp: 2.874 ± 0.053	3.162GluGlu: 3.162 ± 0.059	1.736GluPhe: 1.736 ± 0.04	4.293GluGly: 4.293 ± 0.058	1.325GluHis: 1.325 ± 0.033	2.511GluIle: 2.511 ± 0.043	1.356GluLys: 1.356 ± 0.037	6.694GluLeu: 6.694 ± 0.094	1.03GluMet: 1.03 ± 0.03	1.04GluAsn: 1.04 ± 0.033	3.126GluPro: 3.126 ± 0.058	2.323GluGln: 2.323 ± 0.045	4.743GluArg: 4.743 ± 0.072	3.129GluSer: 3.129 ± 0.052	2.988GluThr: 2.988 ± 0.055	5.279GluVal: 5.279 ± 0.075	0.799GluTrp: 0.799 ± 0.026	1.055GluTyr: 1.055 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.764PheAla: 3.764 ± 0.057	0.221PheCys: 0.221 ± 0.015	2.418PheAsp: 2.418 ± 0.048	1.827PheGlu: 1.827 ± 0.039	1.022PhePhe: 1.022 ± 0.032	3.193PheGly: 3.193 ± 0.056	0.63PheHis: 0.63 ± 0.022	1.196PheIle: 1.196 ± 0.037	0.654PheLys: 0.654 ± 0.024	2.863PheLeu: 2.863 ± 0.057	0.545PheMet: 0.545 ± 0.022	0.85PheAsn: 0.85 ± 0.028	1.389PhePro: 1.389 ± 0.034	0.804PheGln: 0.804 ± 0.026	1.812PheArg: 1.812 ± 0.038	1.802PheSer: 1.802 ± 0.037	2.129PheThr: 2.129 ± 0.04	2.671PheVal: 2.671 ± 0.047	0.506PheTrp: 0.506 ± 0.021	0.632PheTyr: 0.632 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.644GlyAla: 9.644 ± 0.105	0.755GlyCys: 0.755 ± 0.027	5.185GlyAsp: 5.185 ± 0.071	4.918GlyGlu: 4.918 ± 0.067	3.202GlyPhe: 3.202 ± 0.053	7.274GlyGly: 7.274 ± 0.106	1.874GlyHis: 1.874 ± 0.043	4.149GlyIle: 4.149 ± 0.071	2.261GlyLys: 2.261 ± 0.044	8.993GlyLeu: 8.993 ± 0.081	2.111GlyMet: 2.111 ± 0.047	2.063GlyAsn: 2.063 ± 0.048	3.736GlyPro: 3.736 ± 0.052	3.045GlyGln: 3.045 ± 0.048	6.713GlyArg: 6.713 ± 0.094	5.609GlySer: 5.609 ± 0.086	5.348GlyThr: 5.348 ± 0.073	7.653GlyVal: 7.653 ± 0.08	1.874GlyTrp: 1.874 ± 0.044	2.213GlyTyr: 2.213 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.17HisAla: 2.17 ± 0.042	0.138HisCys: 0.138 ± 0.009	1.296HisAsp: 1.296 ± 0.034	1.178HisGlu: 1.178 ± 0.031	0.629HisPhe: 0.629 ± 0.021	1.849HisGly: 1.849 ± 0.045	0.545HisHis: 0.545 ± 0.024	0.769HisIle: 0.769 ± 0.024	0.359HisLys: 0.359 ± 0.016	2.231HisLeu: 2.231 ± 0.038	0.327HisMet: 0.327 ± 0.015	0.445HisAsn: 0.445 ± 0.017	1.427HisPro: 1.427 ± 0.032	0.641HisGln: 0.641 ± 0.027	1.724HisArg: 1.724 ± 0.046	0.977HisSer: 0.977 ± 0.035	1.049HisThr: 1.049 ± 0.03	1.564HisVal: 1.564 ± 0.039	0.314HisTrp: 0.314 ± 0.016	0.446HisTyr: 0.446 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.959IleAla: 5.959 ± 0.074	0.323IleCys: 0.323 ± 0.018	3.268IleAsp: 3.268 ± 0.056	2.688IleGlu: 2.688 ± 0.049	1.122IlePhe: 1.122 ± 0.033	4.374IleGly: 4.374 ± 0.072	0.746IleHis: 0.746 ± 0.026	1.663IleIle: 1.663 ± 0.041	0.866IleLys: 0.866 ± 0.027	3.423IleLeu: 3.423 ± 0.06	0.672IleMet: 0.672 ± 0.026	1.048IleAsn: 1.048 ± 0.034	2.172IlePro: 2.172 ± 0.044	1.04IleGln: 1.04 ± 0.029	2.662IleArg: 2.662 ± 0.043	2.381IleSer: 2.381 ± 0.05	2.715IleThr: 2.715 ± 0.048	4.058IleVal: 4.058 ± 0.063	0.576IleTrp: 0.576 ± 0.023	0.82IleTyr: 0.82 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.937LysAla: 2.937 ± 0.053	0.117LysCys: 0.117 ± 0.009	1.12LysAsp: 1.12 ± 0.035	1.155LysGlu: 1.155 ± 0.035	0.622LysPhe: 0.622 ± 0.022	1.8LysGly: 1.8 ± 0.04	0.456LysHis: 0.456 ± 0.019	0.954LysIle: 0.954 ± 0.032	0.738LysLys: 0.738 ± 0.026	2.266LysLeu: 2.266 ± 0.049	0.457LysMet: 0.457 ± 0.019	0.458LysAsn: 0.458 ± 0.018	1.24LysPro: 1.24 ± 0.035	0.745LysGln: 0.745 ± 0.025	1.623LysArg: 1.623 ± 0.044	1.293LysSer: 1.293 ± 0.033	1.384LysThr: 1.384 ± 0.042	2.181LysVal: 2.181 ± 0.046	0.312LysTrp: 0.312 ± 0.016	0.476LysTyr: 0.476 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.842LeuAla: 13.842 ± 0.149	0.648LeuCys: 0.648 ± 0.022	6.65LeuAsp: 6.65 ± 0.086	5.098LeuGlu: 5.098 ± 0.076	2.858LeuPhe: 2.858 ± 0.064	9.341LeuGly: 9.341 ± 0.098	1.928LeuHis: 1.928 ± 0.047	4.693LeuIle: 4.693 ± 0.066	2.176LeuLys: 2.176 ± 0.046	10.57LeuLeu: 10.57 ± 0.124	1.952LeuMet: 1.952 ± 0.04	2.32LeuAsn: 2.32 ± 0.046	5.736LeuPro: 5.736 ± 0.07	2.538LeuGln: 2.538 ± 0.045	7.597LeuArg: 7.597 ± 0.092	6.09LeuSer: 6.09 ± 0.079	6.972LeuThr: 6.972 ± 0.08	8.922LeuVal: 8.922 ± 0.111	1.311LeuTrp: 1.311 ± 0.035	1.616LeuTyr: 1.616 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.452MetAla: 2.452 ± 0.048	0.153MetCys: 0.153 ± 0.012	0.863MetAsp: 0.863 ± 0.026	0.806MetGlu: 0.806 ± 0.025	0.6MetPhe: 0.6 ± 0.023	1.578MetGly: 1.578 ± 0.043	0.361MetHis: 0.361 ± 0.017	0.911MetIle: 0.911 ± 0.029	0.521MetLys: 0.521 ± 0.021	2.122MetLeu: 2.122 ± 0.042	0.404MetMet: 0.404 ± 0.019	0.567MetAsn: 0.567 ± 0.02	1.109MetPro: 1.109 ± 0.028	0.583MetGln: 0.583 ± 0.022	1.444MetArg: 1.444 ± 0.033	1.504MetSer: 1.504 ± 0.032	1.673MetThr: 1.673 ± 0.041	1.643MetVal: 1.643 ± 0.036	0.271MetTrp: 0.271 ± 0.015	0.297MetTyr: 0.297 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.43AsnAla: 2.43 ± 0.045	0.139AsnCys: 0.139 ± 0.011	1.285AsnAsp: 1.285 ± 0.037	1.13AsnGlu: 1.13 ± 0.031	0.657AsnPhe: 0.657 ± 0.024	2.056AsnGly: 2.056 ± 0.048	0.481AsnHis: 0.481 ± 0.018	0.905AsnIle: 0.905 ± 0.03	0.461AsnLys: 0.461 ± 0.021	2.3AsnLeu: 2.3 ± 0.049	0.437AsnMet: 0.437 ± 0.017	0.657AsnAsn: 0.657 ± 0.025	1.748AsnPro: 1.748 ± 0.043	0.833AsnGln: 0.833 ± 0.026	1.593AsnArg: 1.593 ± 0.039	1.16AsnSer: 1.16 ± 0.029	1.27AsnThr: 1.27 ± 0.036	1.724AsnVal: 1.724 ± 0.039	0.397AsnTrp: 0.397 ± 0.018	0.584AsnTyr: 0.584 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.236ProAla: 6.236 ± 0.069	0.279ProCys: 0.279 ± 0.016	3.843ProAsp: 3.843 ± 0.061	3.966ProGlu: 3.966 ± 0.062	1.548ProPhe: 1.548 ± 0.035	5.279ProGly: 5.279 ± 0.069	1.078ProHis: 1.078 ± 0.032	2.06ProIle: 2.06 ± 0.038	1.182ProLys: 1.182 ± 0.03	4.678ProLeu: 4.678 ± 0.064	1.071ProMet: 1.071 ± 0.033	1.195ProAsn: 1.195 ± 0.027	2.539ProPro: 2.539 ± 0.062	1.568ProGln: 1.568 ± 0.04	3.266ProArg: 3.266 ± 0.053	3.628ProSer: 3.628 ± 0.056	4.144ProThr: 4.144 ± 0.096	4.678ProVal: 4.678 ± 0.069	0.887ProTrp: 0.887 ± 0.03	1.045ProTyr: 1.045 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.853GlnAla: 3.853 ± 0.064	0.167GlnCys: 0.167 ± 0.011	1.353GlnAsp: 1.353 ± 0.036	1.496GlnGlu: 1.496 ± 0.038	0.947GlnPhe: 0.947 ± 0.027	2.304GlnGly: 2.304 ± 0.049	0.644GlnHis: 0.644 ± 0.02	1.462GlnIle: 1.462 ± 0.035	0.635GlnLys: 0.635 ± 0.026	3.576GlnLeu: 3.576 ± 0.062	0.618GlnMet: 0.618 ± 0.025	0.614GlnAsn: 0.614 ± 0.022	1.867GlnPro: 1.867 ± 0.04	1.314GlnGln: 1.314 ± 0.037	2.551GlnArg: 2.551 ± 0.051	1.657GlnSer: 1.657 ± 0.034	1.588GlnThr: 1.588 ± 0.036	2.874GlnVal: 2.874 ± 0.043	0.581GlnTrp: 0.581 ± 0.023	0.562GlnTyr: 0.562 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.887ArgAla: 7.887 ± 0.1	0.562ArgCys: 0.562 ± 0.022	4.206ArgAsp: 4.206 ± 0.058	4.074ArgGlu: 4.074 ± 0.061	2.516ArgPhe: 2.516 ± 0.047	5.185ArgGly: 5.185 ± 0.07	1.69ArgHis: 1.69 ± 0.037	3.525ArgIle: 3.525 ± 0.057	1.613ArgLys: 1.613 ± 0.038	7.878ArgLeu: 7.878 ± 0.106	1.676ArgMet: 1.676 ± 0.036	1.667ArgAsn: 1.667 ± 0.038	3.844ArgPro: 3.844 ± 0.056	2.495ArgGln: 2.495 ± 0.049	6.629ArgArg: 6.629 ± 0.097	4.262ArgSer: 4.262 ± 0.067	3.914ArgThr: 3.914 ± 0.061	5.654ArgVal: 5.654 ± 0.063	1.313ArgTrp: 1.313 ± 0.037	1.716ArgTyr: 1.716 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.755SerAla: 6.755 ± 0.084	0.411SerCys: 0.411 ± 0.019	3.422SerAsp: 3.422 ± 0.052	3.175SerGlu: 3.175 ± 0.054	1.892SerPhe: 1.892 ± 0.044	5.925SerGly: 5.925 ± 0.073	1.085SerHis: 1.085 ± 0.029	2.541SerIle: 2.541 ± 0.046	1.322SerLys: 1.322 ± 0.033	5.814SerLeu: 5.814 ± 0.08	1.342SerMet: 1.342 ± 0.035	1.291SerAsn: 1.291 ± 0.037	3.238SerPro: 3.238 ± 0.056	1.669SerGln: 1.669 ± 0.039	4.007SerArg: 4.007 ± 0.063	3.641SerSer: 3.641 ± 0.065	3.787SerThr: 3.787 ± 0.056	4.859SerVal: 4.859 ± 0.061	1.005SerTrp: 1.005 ± 0.031	1.337SerTyr: 1.337 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.341ThrAla: 7.341 ± 0.1	0.442ThrCys: 0.442 ± 0.02	3.532ThrAsp: 3.532 ± 0.055	3.052ThrGlu: 3.052 ± 0.056	1.967ThrPhe: 1.967 ± 0.046	5.76ThrGly: 5.76 ± 0.08	1.211ThrHis: 1.211 ± 0.034	2.695ThrIle: 2.695 ± 0.058	1.264ThrLys: 1.264 ± 0.028	6.186ThrLeu: 6.186 ± 0.079	1.182ThrMet: 1.182 ± 0.032	1.409ThrAsn: 1.409 ± 0.035	4.351ThrPro: 4.351 ± 0.083	1.776ThrGln: 1.776 ± 0.04	4.085ThrArg: 4.085 ± 0.059	3.719ThrSer: 3.719 ± 0.062	4.029ThrThr: 4.029 ± 0.075	5.698ThrVal: 5.698 ± 0.079	1.033ThrTrp: 1.033 ± 0.03	1.303ThrTyr: 1.303 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	11.397ValAla: 11.397 ± 0.132	0.661ValCys: 0.661 ± 0.024	5.803ValAsp: 5.803 ± 0.068	5.317ValGlu: 5.317 ± 0.08	2.64ValPhe: 2.64 ± 0.052	7.606ValGly: 7.606 ± 0.092	1.544ValHis: 1.544 ± 0.037	3.744ValIle: 3.744 ± 0.06	1.819ValLys: 1.819 ± 0.042	8.81ValLeu: 8.81 ± 0.107	1.61ValMet: 1.61 ± 0.037	1.932ValAsn: 1.932 ± 0.041	4.36ValPro: 4.36 ± 0.062	2.069ValGln: 2.069 ± 0.04	5.573ValArg: 5.573 ± 0.08	5.207ValSer: 5.207 ± 0.073	5.948ValThr: 5.948 ± 0.082	8.394ValVal: 8.394 ± 0.108	1.181ValTrp: 1.181 ± 0.034	1.371ValTyr: 1.371 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.806TrpAla: 1.806 ± 0.042	0.159TrpCys: 0.159 ± 0.013	0.814TrpAsp: 0.814 ± 0.028	0.758TrpGlu: 0.758 ± 0.027	0.626TrpPhe: 0.626 ± 0.022	1.173TrpGly: 1.173 ± 0.032	0.38TrpHis: 0.38 ± 0.019	0.621TrpIle: 0.621 ± 0.025	0.382TrpLys: 0.382 ± 0.018	1.976TrpLeu: 1.976 ± 0.046	0.337TrpMet: 0.337 ± 0.016	0.418TrpAsn: 0.418 ± 0.017	0.819TrpPro: 0.819 ± 0.024	0.627TrpGln: 0.627 ± 0.025	1.353TrpArg: 1.353 ± 0.039	0.999TrpSer: 0.999 ± 0.029	0.953TrpThr: 0.953 ± 0.029	1.311TrpVal: 1.311 ± 0.033	0.371TrpTrp: 0.371 ± 0.018	0.325TrpTyr: 0.325 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.246TyrAla: 2.246 ± 0.044	0.171TyrCys: 0.171 ± 0.012	1.236TyrAsp: 1.236 ± 0.029	1.117TyrGlu: 1.117 ± 0.028	0.727TyrPhe: 0.727 ± 0.025	1.781TyrGly: 1.781 ± 0.043	0.392TyrHis: 0.392 ± 0.019	0.605TyrIle: 0.605 ± 0.024	0.393TyrLys: 0.393 ± 0.018	2.322TyrLeu: 2.322 ± 0.045	0.279TyrMet: 0.279 ± 0.016	0.467TyrAsn: 0.467 ± 0.021	1.078TyrPro: 1.078 ± 0.035	0.687TyrGln: 0.687 ± 0.026	1.74TyrArg: 1.74 ± 0.038	1.178TyrSer: 1.178 ± 0.03	1.102TyrThr: 1.102 ± 0.039	1.639TyrVal: 1.639 ± 0.04	0.352TyrTrp: 0.352 ± 0.018	0.454TyrTyr: 0.454 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3715 proteins (1232246 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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