Human papillomavirus type 88

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 5

Average proteome isoelectric point is 6.3

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A8R8N1|A8R8N1_9PAPI Replication protein E1 OS=Human papillomavirus type 88 OX=337054 GN=E1 PE=3 SV=1
MM1 pKa = 7.45IGKK4 pKa = 9.12EE5 pKa = 3.69PSINDD10 pKa = 3.58LEE12 pKa = 4.63IKK14 pKa = 10.57LEE16 pKa = 4.07EE17 pKa = 4.35HH18 pKa = 6.23VLPANLLSNEE28 pKa = 4.07VLSSDD33 pKa = 4.04EE34 pKa = 3.96EE35 pKa = 4.38TQEE38 pKa = 3.96EE39 pKa = 4.81EE40 pKa = 3.9EE41 pKa = 4.56RR42 pKa = 11.84EE43 pKa = 4.03PFQIDD48 pKa = 3.52TSCAFCEE55 pKa = 3.87AGVRR59 pKa = 11.84VFVLASPAGIRR70 pKa = 11.84TLQQLLLAEE79 pKa = 4.82ISISCPGCSRR89 pKa = 11.84NNFRR93 pKa = 11.84HH94 pKa = 5.91GRR96 pKa = 11.84PQQ98 pKa = 2.92

Molecular weight: 10.9 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A8R8N4|A8R8N4_9PAPI E4 protein OS=Human papillomavirus type 88 OX=337054 GN=E4 PE=4 SV=1
MM1 pKa = 7.49ARR3 pKa = 11.84MEE5 pKa = 4.24TQEE8 pKa = 4.06TLTEE12 pKa = 4.05RR13 pKa = 11.84FVALQDD19 pKa = 4.49AILNLIEE26 pKa = 5.42RR27 pKa = 11.84GEE29 pKa = 4.14TDD31 pKa = 3.72LRR33 pKa = 11.84SQIQYY38 pKa = 9.21WEE40 pKa = 4.3LVRR43 pKa = 11.84KK44 pKa = 8.35EE45 pKa = 4.0QVILYY50 pKa = 6.74YY51 pKa = 10.56ARR53 pKa = 11.84KK54 pKa = 9.58SGYY57 pKa = 9.69NRR59 pKa = 11.84LGLQPTPAPAVSEE72 pKa = 4.39YY73 pKa = 10.31NAKK76 pKa = 9.73QAIHH80 pKa = 6.27LQLMLKK86 pKa = 10.16SLEE89 pKa = 3.9KK90 pKa = 10.84SKK92 pKa = 10.38FAKK95 pKa = 10.28EE96 pKa = 3.82PWSLTDD102 pKa = 4.63ASAEE106 pKa = 4.05LVNTPPRR113 pKa = 11.84DD114 pKa = 3.68CFKK117 pKa = 11.04KK118 pKa = 10.54GGFTVTVYY126 pKa = 10.67FDD128 pKa = 3.53NDD130 pKa = 3.57RR131 pKa = 11.84EE132 pKa = 4.19NSFPYY137 pKa = 8.68TQWEE141 pKa = 4.23HH142 pKa = 7.75IYY144 pKa = 10.83YY145 pKa = 9.87QDD147 pKa = 5.37QNEE150 pKa = 4.18QWHH153 pKa = 5.97KK154 pKa = 10.31VPGGVDD160 pKa = 3.51HH161 pKa = 7.16NGLYY165 pKa = 10.33YY166 pKa = 10.66DD167 pKa = 4.5EE168 pKa = 5.65EE169 pKa = 4.44NTNEE173 pKa = 3.71RR174 pKa = 11.84VYY176 pKa = 10.98FLLFEE181 pKa = 4.94PEE183 pKa = 4.06SQKK186 pKa = 11.07YY187 pKa = 9.76GSSGQWTVHH196 pKa = 5.21YY197 pKa = 10.91KK198 pKa = 8.78NTTVSASATSSSRR211 pKa = 11.84RR212 pKa = 11.84SSPISTKK219 pKa = 10.08TDD221 pKa = 3.54FDD223 pKa = 3.61ATTAGNTTTSAPQRR237 pKa = 11.84SPRR240 pKa = 11.84KK241 pKa = 8.79RR242 pKa = 11.84LQEE245 pKa = 4.18AVSSTTSPPAHH256 pKa = 6.78NLRR259 pKa = 11.84SPGRR263 pKa = 11.84GRR265 pKa = 11.84GEE267 pKa = 4.13GEE269 pKa = 3.77RR270 pKa = 11.84TSGAKK275 pKa = 9.35RR276 pKa = 11.84RR277 pKa = 11.84RR278 pKa = 11.84TATDD282 pKa = 3.21GNTLGEE288 pKa = 4.54SVPSPSQVGSRR299 pKa = 11.84HH300 pKa = 5.66RR301 pKa = 11.84APEE304 pKa = 3.74RR305 pKa = 11.84SGLSRR310 pKa = 11.84LGRR313 pKa = 11.84LQADD317 pKa = 3.04AWDD320 pKa = 4.26PPLIIIKK327 pKa = 10.59GPANTLKK334 pKa = 10.47CWRR337 pKa = 11.84NRR339 pKa = 11.84MKK341 pKa = 10.82KK342 pKa = 9.84NSSSNLVCSSVWRR355 pKa = 11.84WIDD358 pKa = 3.21STTHH362 pKa = 5.49EE363 pKa = 4.27NSRR366 pKa = 11.84MLVAFQNTAEE376 pKa = 4.22RR377 pKa = 11.84TRR379 pKa = 11.84FLNSVTLPKK388 pKa = 10.03GTTYY392 pKa = 11.46AFGYY396 pKa = 10.35LDD398 pKa = 3.51SLL400 pKa = 4.27

Molecular weight: 45.26 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2472

98

607

353.1

39.83

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.866 ± 0.382

2.225 ± 0.837

6.189 ± 0.514

6.756 ± 0.761

4.854 ± 0.535

5.663 ± 0.636

1.861 ± 0.086

5.461 ± 1.071

4.733 ± 0.685

9.223 ± 0.781

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.659 ± 0.318

5.299 ± 0.5

6.675 ± 1.207

3.883 ± 0.688

6.23 ± 0.757

7.241 ± 0.761

6.472 ± 0.836

5.542 ± 0.503

1.173 ± 0.281

2.994 ± 0.361
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski