Amino acid dipepetide frequency for Elaphomyces granulatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.627AlaAla: 7.627 ± 0.057
0.943AlaCys: 0.943 ± 0.018
3.94AlaAsp: 3.94 ± 0.034
4.765AlaGlu: 4.765 ± 0.045
2.985AlaPhe: 2.985 ± 0.034
5.071AlaGly: 5.071 ± 0.043
1.602AlaHis: 1.602 ± 0.024
4.288AlaIle: 4.288 ± 0.039
3.677AlaLys: 3.677 ± 0.039
7.449AlaLeu: 7.449 ± 0.062
1.686AlaMet: 1.686 ± 0.024
2.793AlaAsn: 2.793 ± 0.029
3.977AlaPro: 3.977 ± 0.046
2.905AlaGln: 2.905 ± 0.028
4.733AlaArg: 4.733 ± 0.041
6.924AlaSer: 6.924 ± 0.047
4.723AlaThr: 4.723 ± 0.041
5.136AlaVal: 5.136 ± 0.042
0.97AlaTrp: 0.97 ± 0.022
1.972AlaTyr: 1.972 ± 0.028
0.001AlaXaa: 0.001 ± 0.001
Cys
0.796CysAla: 0.796 ± 0.015
0.237CysCys: 0.237 ± 0.008
0.637CysAsp: 0.637 ± 0.016
0.646CysGlu: 0.646 ± 0.016
0.525CysPhe: 0.525 ± 0.013
0.893CysGly: 0.893 ± 0.017
0.352CysHis: 0.352 ± 0.009
0.683CysIle: 0.683 ± 0.015
0.522CysLys: 0.522 ± 0.013
1.307CysLeu: 1.307 ± 0.023
0.243CysMet: 0.243 ± 0.008
0.416CysAsn: 0.416 ± 0.011
0.65CysPro: 0.65 ± 0.015
0.487CysGln: 0.487 ± 0.012
0.798CysArg: 0.798 ± 0.017
0.941CysSer: 0.941 ± 0.018
0.615CysThr: 0.615 ± 0.014
0.743CysVal: 0.743 ± 0.015
0.209CysTrp: 0.209 ± 0.008
0.354CysTyr: 0.354 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
4.208AspAla: 4.208 ± 0.041
0.66AspCys: 0.66 ± 0.013
4.352AspAsp: 4.352 ± 0.055
4.446AspGlu: 4.446 ± 0.048
2.229AspPhe: 2.229 ± 0.022
4.067AspGly: 4.067 ± 0.041
1.387AspHis: 1.387 ± 0.023
3.427AspIle: 3.427 ± 0.035
2.268AspLys: 2.268 ± 0.027
5.33AspLeu: 5.33 ± 0.038
1.179AspMet: 1.179 ± 0.019
2.008AspAsn: 2.008 ± 0.022
3.437AspPro: 3.437 ± 0.036
1.952AspGln: 1.952 ± 0.025
3.366AspArg: 3.366 ± 0.044
4.397AspSer: 4.397 ± 0.043
2.87AspThr: 2.87 ± 0.029
3.644AspVal: 3.644 ± 0.033
0.822AspTrp: 0.822 ± 0.015
1.543AspTyr: 1.543 ± 0.023
0.001AspXaa: 0.001 ± 0.0
Glu
5.09GluAla: 5.09 ± 0.048
0.623GluCys: 0.623 ± 0.014
4.206GluAsp: 4.206 ± 0.045
5.538GluGlu: 5.538 ± 0.068
2.053GluPhe: 2.053 ± 0.023
3.594GluGly: 3.594 ± 0.035
1.338GluHis: 1.338 ± 0.02
3.396GluIle: 3.396 ± 0.036
3.873GluLys: 3.873 ± 0.047
5.409GluLeu: 5.409 ± 0.048
1.454GluMet: 1.454 ± 0.022
2.517GluAsn: 2.517 ± 0.027
2.678GluPro: 2.678 ± 0.037
2.481GluGln: 2.481 ± 0.034
4.254GluArg: 4.254 ± 0.048
4.538GluSer: 4.538 ± 0.041
3.496GluThr: 3.496 ± 0.032
3.525GluVal: 3.525 ± 0.034
0.887GluTrp: 0.887 ± 0.018
1.654GluTyr: 1.654 ± 0.02
0.001GluXaa: 0.001 ± 0.0
Phe
2.811PheAla: 2.811 ± 0.029
0.59PheCys: 0.59 ± 0.013
2.326PheAsp: 2.326 ± 0.027
2.173PheGlu: 2.173 ± 0.028
1.622PhePhe: 1.622 ± 0.023
2.715PheGly: 2.715 ± 0.034
0.942PheHis: 0.942 ± 0.014
1.878PheIle: 1.878 ± 0.027
1.535PheLys: 1.535 ± 0.022
3.72PheLeu: 3.72 ± 0.036
0.732PheMet: 0.732 ± 0.015
1.458PheAsn: 1.458 ± 0.022
2.058PhePro: 2.058 ± 0.026
1.485PheGln: 1.485 ± 0.023
2.189PheArg: 2.189 ± 0.027
3.217PheSer: 3.217 ± 0.029
2.064PheThr: 2.064 ± 0.026
2.299PheVal: 2.299 ± 0.032
0.564PheTrp: 0.564 ± 0.014
1.091PheTyr: 1.091 ± 0.02
0.0PheXaa: 0.0 ± 0.0
Gly
4.511GlyAla: 4.511 ± 0.037
0.803GlyCys: 0.803 ± 0.015
3.697GlyAsp: 3.697 ± 0.037
3.617GlyGlu: 3.617 ± 0.037
2.669GlyPhe: 2.669 ± 0.031
5.23GlyGly: 5.23 ± 0.054
1.672GlyHis: 1.672 ± 0.024
3.661GlyIle: 3.661 ± 0.039
3.438GlyLys: 3.438 ± 0.041
5.889GlyLeu: 5.889 ± 0.051
1.438GlyMet: 1.438 ± 0.022
2.58GlyAsn: 2.58 ± 0.031
3.29GlyPro: 3.29 ± 0.042
2.463GlyGln: 2.463 ± 0.025
4.266GlyArg: 4.266 ± 0.039
5.678GlySer: 5.678 ± 0.048
3.691GlyThr: 3.691 ± 0.032
4.07GlyVal: 4.07 ± 0.037
1.021GlyTrp: 1.021 ± 0.018
2.012GlyTyr: 2.012 ± 0.028
0.002GlyXaa: 0.002 ± 0.001
His
1.679HisAla: 1.679 ± 0.025
0.33HisCys: 0.33 ± 0.011
1.332HisAsp: 1.332 ± 0.021
1.319HisGlu: 1.319 ± 0.019
0.943HisPhe: 0.943 ± 0.017
1.652HisGly: 1.652 ± 0.022
0.9HisHis: 0.9 ± 0.018
1.271HisIle: 1.271 ± 0.018
0.868HisLys: 0.868 ± 0.015
2.366HisLeu: 2.366 ± 0.026
0.433HisMet: 0.433 ± 0.01
0.823HisAsn: 0.823 ± 0.015
1.78HisPro: 1.78 ± 0.021
1.075HisGln: 1.075 ± 0.023
1.69HisArg: 1.69 ± 0.022
1.988HisSer: 1.988 ± 0.028
1.227HisThr: 1.227 ± 0.022
1.408HisVal: 1.408 ± 0.022
0.326HisTrp: 0.326 ± 0.011
0.686HisTyr: 0.686 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
4.08IleAla: 4.08 ± 0.04
0.79IleCys: 0.79 ± 0.014
3.079IleAsp: 3.079 ± 0.035
3.102IleGlu: 3.102 ± 0.029
2.158IlePhe: 2.158 ± 0.03
3.207IleGly: 3.207 ± 0.04
1.313IleHis: 1.313 ± 0.019
2.71IleIle: 2.71 ± 0.029
2.326IleLys: 2.326 ± 0.026
5.041IleLeu: 5.041 ± 0.042
1.004IleMet: 1.004 ± 0.017
1.923IleAsn: 1.923 ± 0.026
3.269IlePro: 3.269 ± 0.033
2.042IleGln: 2.042 ± 0.024
3.193IleArg: 3.193 ± 0.031
4.46IleSer: 4.46 ± 0.034
2.839IleThr: 2.839 ± 0.026
3.231IleVal: 3.231 ± 0.037
0.727IleTrp: 0.727 ± 0.015
1.495IleTyr: 1.495 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
3.971LysAla: 3.971 ± 0.044
0.501LysCys: 0.501 ± 0.012
2.762LysAsp: 2.762 ± 0.031
3.491LysGlu: 3.491 ± 0.046
1.496LysPhe: 1.496 ± 0.021
2.932LysGly: 2.932 ± 0.03
1.092LysHis: 1.092 ± 0.018
2.489LysIle: 2.489 ± 0.03
3.163LysLys: 3.163 ± 0.05
4.287LysLeu: 4.287 ± 0.045
1.068LysMet: 1.068 ± 0.021
1.796LysAsn: 1.796 ± 0.021
2.597LysPro: 2.597 ± 0.03
1.91LysGln: 1.91 ± 0.027
3.693LysArg: 3.693 ± 0.04
3.602LysSer: 3.602 ± 0.029
2.724LysThr: 2.724 ± 0.032
2.751LysVal: 2.751 ± 0.028
0.645LysTrp: 0.645 ± 0.013
1.369LysTyr: 1.369 ± 0.021
0.0LysXaa: 0.0 ± 0.0
Leu
7.31LeuAla: 7.31 ± 0.057
1.222LeuCys: 1.222 ± 0.021
5.536LeuAsp: 5.536 ± 0.047
5.897LeuGlu: 5.897 ± 0.052
3.418LeuPhe: 3.418 ± 0.035
5.882LeuGly: 5.882 ± 0.05
2.307LeuHis: 2.307 ± 0.026
4.244LeuIle: 4.244 ± 0.043
4.525LeuLys: 4.525 ± 0.037
8.914LeuLeu: 8.914 ± 0.074
1.712LeuMet: 1.712 ± 0.023
3.41LeuAsn: 3.41 ± 0.03
5.682LeuPro: 5.682 ± 0.044
4.235LeuGln: 4.235 ± 0.044
6.295LeuArg: 6.295 ± 0.048
8.069LeuSer: 8.069 ± 0.056
4.956LeuThr: 4.956 ± 0.039
5.45LeuVal: 5.45 ± 0.05
1.175LeuTrp: 1.175 ± 0.021
2.44LeuTyr: 2.44 ± 0.034
0.001LeuXaa: 0.001 ± 0.001
Met
1.981MetAla: 1.981 ± 0.024
0.22MetCys: 0.22 ± 0.008
1.197MetAsp: 1.197 ± 0.02
1.318MetGlu: 1.318 ± 0.019
0.707MetPhe: 0.707 ± 0.015
1.302MetGly: 1.302 ± 0.021
0.435MetHis: 0.435 ± 0.012
1.012MetIle: 1.012 ± 0.016
0.999MetLys: 0.999 ± 0.02
1.824MetLeu: 1.824 ± 0.025
0.526MetMet: 0.526 ± 0.013
0.784MetAsn: 0.784 ± 0.015
1.1MetPro: 1.1 ± 0.018
0.822MetGln: 0.822 ± 0.015
1.213MetArg: 1.213 ± 0.019
1.755MetSer: 1.755 ± 0.025
1.213MetThr: 1.213 ± 0.019
1.235MetVal: 1.235 ± 0.02
0.251MetTrp: 0.251 ± 0.008
0.532MetTyr: 0.532 ± 0.017
0.001MetXaa: 0.001 ± 0.0
Asn
2.959AsnAla: 2.959 ± 0.03
0.469AsnCys: 0.469 ± 0.011
2.11AsnAsp: 2.11 ± 0.024
2.137AsnGlu: 2.137 ± 0.024
1.407AsnPhe: 1.407 ± 0.018
2.96AsnGly: 2.96 ± 0.033
0.888AsnHis: 0.888 ± 0.019
2.231AsnIle: 2.231 ± 0.029
1.567AsnLys: 1.567 ± 0.024
3.544AsnLeu: 3.544 ± 0.036
0.799AsnMet: 0.799 ± 0.014
1.649AsnAsn: 1.649 ± 0.029
2.557AsnPro: 2.557 ± 0.028
1.394AsnGln: 1.394 ± 0.022
2.225AsnArg: 2.225 ± 0.025
3.018AsnSer: 3.018 ± 0.03
2.103AsnThr: 2.103 ± 0.024
2.421AsnVal: 2.421 ± 0.028
0.519AsnTrp: 0.519 ± 0.013
1.051AsnTyr: 1.051 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
4.518ProAla: 4.518 ± 0.052
0.523ProCys: 0.523 ± 0.014
3.255ProAsp: 3.255 ± 0.036
3.698ProGlu: 3.698 ± 0.04
2.135ProPhe: 2.135 ± 0.026
3.764ProGly: 3.764 ± 0.044
1.33ProHis: 1.33 ± 0.021
2.67ProIle: 2.67 ± 0.027
2.556ProLys: 2.556 ± 0.033
5.024ProLeu: 5.024 ± 0.041
0.98ProMet: 0.98 ± 0.016
2.309ProAsn: 2.309 ± 0.027
5.43ProPro: 5.43 ± 0.094
2.489ProGln: 2.489 ± 0.04
3.535ProArg: 3.535 ± 0.042
6.501ProSer: 6.501 ± 0.078
3.829ProThr: 3.829 ± 0.041
3.53ProVal: 3.53 ± 0.04
0.67ProTrp: 0.67 ± 0.015
1.479ProTyr: 1.479 ± 0.023
0.002ProXaa: 0.002 ± 0.001
Gln
3.14GlnAla: 3.14 ± 0.029
0.439GlnCys: 0.439 ± 0.011
2.053GlnAsp: 2.053 ± 0.025
2.531GlnGlu: 2.531 ± 0.034
1.345GlnPhe: 1.345 ± 0.022
2.481GlnGly: 2.481 ± 0.033
1.075GlnHis: 1.075 ± 0.021
2.018GlnIle: 2.018 ± 0.023
2.079GlnLys: 2.079 ± 0.021
3.639GlnLeu: 3.639 ± 0.042
0.865GlnMet: 0.865 ± 0.016
1.659GlnAsn: 1.659 ± 0.024
2.475GlnPro: 2.475 ± 0.042
2.619GlnGln: 2.619 ± 0.077
2.907GlnArg: 2.907 ± 0.027
3.342GlnSer: 3.342 ± 0.043
2.322GlnThr: 2.322 ± 0.023
2.182GlnVal: 2.182 ± 0.024
0.531GlnTrp: 0.531 ± 0.012
1.098GlnTyr: 1.098 ± 0.019
0.001GlnXaa: 0.001 ± 0.001
Arg
4.61ArgAla: 4.61 ± 0.043
0.761ArgCys: 0.761 ± 0.017
3.646ArgAsp: 3.646 ± 0.042
4.203ArgGlu: 4.203 ± 0.043
2.322ArgPhe: 2.322 ± 0.03
3.836ArgGly: 3.836 ± 0.041
1.69ArgHis: 1.69 ± 0.024
3.223ArgIle: 3.223 ± 0.035
3.779ArgLys: 3.779 ± 0.036
6.069ArgLeu: 6.069 ± 0.045
1.325ArgMet: 1.325 ± 0.019
2.486ArgAsn: 2.486 ± 0.03
3.707ArgPro: 3.707 ± 0.043
2.834ArgGln: 2.834 ± 0.029
5.645ArgArg: 5.645 ± 0.06
5.323ArgSer: 5.323 ± 0.048
3.413ArgThr: 3.413 ± 0.036
3.523ArgVal: 3.523 ± 0.028
0.909ArgTrp: 0.909 ± 0.015
1.733ArgTyr: 1.733 ± 0.022
0.0ArgXaa: 0.0 ± 0.0
Ser
6.298SerAla: 6.298 ± 0.049
0.867SerCys: 0.867 ± 0.015
4.388SerAsp: 4.388 ± 0.04
4.34SerGlu: 4.34 ± 0.04
3.205SerPhe: 3.205 ± 0.031
5.606SerGly: 5.606 ± 0.053
2.109SerHis: 2.109 ± 0.026
4.367SerIle: 4.367 ± 0.042
3.935SerLys: 3.935 ± 0.041
7.929SerLeu: 7.929 ± 0.054
1.703SerMet: 1.703 ± 0.022
3.388SerAsn: 3.388 ± 0.039
5.992SerPro: 5.992 ± 0.081
3.567SerGln: 3.567 ± 0.035
5.656SerArg: 5.656 ± 0.05
9.708SerSer: 9.708 ± 0.097
5.706SerThr: 5.706 ± 0.052
4.816SerVal: 4.816 ± 0.039
1.078SerTrp: 1.078 ± 0.019
2.066SerTyr: 2.066 ± 0.022
0.001SerXaa: 0.001 ± 0.0
Thr
4.823ThrAla: 4.823 ± 0.041
0.699ThrCys: 0.699 ± 0.014
2.867ThrAsp: 2.867 ± 0.027
3.081ThrGlu: 3.081 ± 0.03
2.18ThrPhe: 2.18 ± 0.025
3.96ThrGly: 3.96 ± 0.038
1.204ThrHis: 1.204 ± 0.02
3.078ThrIle: 3.078 ± 0.035
2.513ThrLys: 2.513 ± 0.031
5.363ThrLeu: 5.363 ± 0.047
1.115ThrMet: 1.115 ± 0.016
2.034ThrAsn: 2.034 ± 0.024
4.058ThrPro: 4.058 ± 0.053
1.998ThrGln: 1.998 ± 0.026
3.195ThrArg: 3.195 ± 0.029
5.378ThrSer: 5.378 ± 0.041
3.908ThrThr: 3.908 ± 0.041
3.715ThrVal: 3.715 ± 0.036
0.735ThrTrp: 0.735 ± 0.016
1.468ThrTyr: 1.468 ± 0.021
0.001ThrXaa: 0.001 ± 0.0
Val
4.853ValAla: 4.853 ± 0.042
0.786ValCys: 0.786 ± 0.017
3.769ValAsp: 3.769 ± 0.037
3.941ValGlu: 3.941 ± 0.038
2.411ValPhe: 2.411 ± 0.03
3.792ValGly: 3.792 ± 0.037
1.376ValHis: 1.376 ± 0.022
3.167ValIle: 3.167 ± 0.035
2.863ValLys: 2.863 ± 0.03
5.57ValLeu: 5.57 ± 0.046
1.255ValMet: 1.255 ± 0.017
2.343ValAsn: 2.343 ± 0.027
3.448ValPro: 3.448 ± 0.036
2.359ValGln: 2.359 ± 0.027
3.514ValArg: 3.514 ± 0.03
4.827ValSer: 4.827 ± 0.039
3.438ValThr: 3.438 ± 0.036
4.155ValVal: 4.155 ± 0.042
0.784ValTrp: 0.784 ± 0.016
1.606ValTyr: 1.606 ± 0.022
0.0ValXaa: 0.0 ± 0.0
Trp
0.974TrpAla: 0.974 ± 0.019
0.188TrpCys: 0.188 ± 0.007
0.846TrpAsp: 0.846 ± 0.016
0.821TrpGlu: 0.821 ± 0.015
0.483TrpPhe: 0.483 ± 0.011
0.841TrpGly: 0.841 ± 0.02
0.326TrpHis: 0.326 ± 0.01
0.739TrpIle: 0.739 ± 0.016
0.789TrpLys: 0.789 ± 0.014
1.285TrpLeu: 1.285 ± 0.019
0.339TrpMet: 0.339 ± 0.009
0.603TrpAsn: 0.603 ± 0.013
0.544TrpPro: 0.544 ± 0.014
0.516TrpGln: 0.516 ± 0.012
0.957TrpArg: 0.957 ± 0.018
0.987TrpSer: 0.987 ± 0.017
0.793TrpThr: 0.793 ± 0.015
0.799TrpVal: 0.799 ± 0.018
0.25TrpTrp: 0.25 ± 0.009
0.369TrpTyr: 0.369 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.924TyrAla: 1.924 ± 0.024
0.403TyrCys: 0.403 ± 0.012
1.596TyrAsp: 1.596 ± 0.021
1.543TyrGlu: 1.543 ± 0.023
1.178TyrPhe: 1.178 ± 0.021
1.912TyrGly: 1.912 ± 0.027
0.759TyrHis: 0.759 ± 0.015
1.435TyrIle: 1.435 ± 0.02
1.064TyrLys: 1.064 ± 0.021
2.717TyrLeu: 2.717 ± 0.03
0.565TyrMet: 0.565 ± 0.014
1.032TyrAsn: 1.032 ± 0.015
1.5TyrPro: 1.5 ± 0.024
1.166TyrGln: 1.166 ± 0.021
1.711TyrArg: 1.711 ± 0.023
2.07TyrSer: 2.07 ± 0.027
1.443TyrThr: 1.443 ± 0.02
1.622TyrVal: 1.622 ± 0.021
0.376TyrTrp: 0.376 ± 0.011
0.884TyrTyr: 0.884 ± 0.017
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.001
0.001XaaCys: 0.001 ± 0.0
0.001XaaAsp: 0.001 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.001XaaGly: 0.001 ± 0.001
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.001XaaLeu: 0.001 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.002XaaPro: 0.002 ± 0.001
0.001XaaGln: 0.001 ± 0.001
0.001XaaArg: 0.001 ± 0.0
0.002XaaSer: 0.002 ± 0.001
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.089XaaXaa: 0.089 ± 0.021
Statistics based on 7169 proteins (3610934 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski