Amino acid dipepetide frequency for Gorilla gorilla gorilla (Western lowland gorilla)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.617AlaAla: 6.617 ± 0.033	1.378AlaCys: 1.378 ± 0.01	2.896AlaAsp: 2.896 ± 0.014	4.787AlaGlu: 4.787 ± 0.021	2.633AlaPhe: 2.633 ± 0.015	4.672AlaGly: 4.672 ± 0.022	1.547AlaHis: 1.547 ± 0.01	2.781AlaIle: 2.781 ± 0.012	3.468AlaLys: 3.468 ± 0.021	7.05AlaLeu: 7.05 ± 0.031	1.5AlaMet: 1.5 ± 0.009	2.007AlaAsn: 2.007 ± 0.01	4.11AlaPro: 4.11 ± 0.022	3.259AlaGln: 3.259 ± 0.015	3.589AlaArg: 3.589 ± 0.018	5.678AlaSer: 5.678 ± 0.019	3.612AlaThr: 3.612 ± 0.016	4.661AlaVal: 4.661 ± 0.018	0.805AlaTrp: 0.805 ± 0.007	1.519AlaTyr: 1.519 ± 0.009	0.003AlaXaa: 0.003 ± 0.0
Cys	1.22CysAla: 1.22 ± 0.01	0.668CysCys: 0.668 ± 0.01	1.009CysAsp: 1.009 ± 0.009	1.321CysGlu: 1.321 ± 0.014	0.844CysPhe: 0.844 ± 0.007	1.769CysGly: 1.769 ± 0.019	0.68CysHis: 0.68 ± 0.006	0.973CysIle: 0.973 ± 0.009	1.181CysLys: 1.181 ± 0.009	2.215CysLeu: 2.215 ± 0.013	0.428CysMet: 0.428 ± 0.004	0.824CysAsn: 0.824 ± 0.009	1.372CysPro: 1.372 ± 0.013	1.088CysGln: 1.088 ± 0.01	1.285CysArg: 1.285 ± 0.009	2.001CysSer: 2.001 ± 0.014	1.101CysThr: 1.101 ± 0.01	1.287CysVal: 1.287 ± 0.01	0.305CysTrp: 0.305 ± 0.004	0.578CysTyr: 0.578 ± 0.006	0.001CysXaa: 0.001 ± 0.0
Asp	2.875AspAla: 2.875 ± 0.013	1.062AspCys: 1.062 ± 0.009	2.629AspAsp: 2.629 ± 0.013	3.47AspGlu: 3.47 ± 0.017	2.115AspPhe: 2.115 ± 0.012	3.328AspGly: 3.328 ± 0.02	1.133AspHis: 1.133 ± 0.008	2.615AspIle: 2.615 ± 0.014	2.569AspLys: 2.569 ± 0.013	4.999AspLeu: 4.999 ± 0.016	1.13AspMet: 1.13 ± 0.008	1.689AspAsn: 1.689 ± 0.01	2.888AspPro: 2.888 ± 0.014	1.839AspGln: 1.839 ± 0.009	2.42AspArg: 2.42 ± 0.012	4.16AspSer: 4.16 ± 0.018	2.467AspThr: 2.467 ± 0.012	3.099AspVal: 3.099 ± 0.017	0.624AspTrp: 0.624 ± 0.007	1.487AspTyr: 1.487 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	5.287GluAla: 5.287 ± 0.023	1.515GluCys: 1.515 ± 0.023	4.491GluAsp: 4.491 ± 0.017	8.071GluGlu: 8.071 ± 0.043	2.073GluPhe: 2.073 ± 0.011	4.215GluGly: 4.215 ± 0.02	1.536GluHis: 1.536 ± 0.008	3.224GluIle: 3.224 ± 0.02	5.545GluLys: 5.545 ± 0.031	6.521GluLeu: 6.521 ± 0.026	1.706GluMet: 1.706 ± 0.012	3.226GluAsn: 3.226 ± 0.016	3.241GluPro: 3.241 ± 0.019	3.161GluGln: 3.161 ± 0.018	4.025GluArg: 4.025 ± 0.018	4.385GluSer: 4.385 ± 0.021	3.43GluThr: 3.43 ± 0.017	4.202GluVal: 4.202 ± 0.022	0.716GluTrp: 0.716 ± 0.006	1.627GluTyr: 1.627 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	1.948PheAla: 1.948 ± 0.011	0.926PheCys: 0.926 ± 0.008	1.67PheAsp: 1.67 ± 0.01	2.029PheGlu: 2.029 ± 0.01	1.592PhePhe: 1.592 ± 0.009	2.178PheGly: 2.178 ± 0.013	1.05PheHis: 1.05 ± 0.007	1.834PheIle: 1.834 ± 0.012	1.823PheLys: 1.823 ± 0.01	4.052PheLeu: 4.052 ± 0.017	0.773PheMet: 0.773 ± 0.006	1.348PheAsn: 1.348 ± 0.01	1.998PhePro: 1.998 ± 0.013	1.81PheGln: 1.81 ± 0.01	1.977PheArg: 1.977 ± 0.011	3.42PheSer: 3.42 ± 0.015	2.046PheThr: 2.046 ± 0.012	2.133PheVal: 2.133 ± 0.01	0.493PheTrp: 0.493 ± 0.005	1.154PheTyr: 1.154 ± 0.007	0.001PheXaa: 0.001 ± 0.0
Gly	4.413GlyAla: 4.413 ± 0.024	1.28GlyCys: 1.28 ± 0.01	3.144GlyAsp: 3.144 ± 0.017	4.217GlyGlu: 4.217 ± 0.025	2.392GlyPhe: 2.392 ± 0.016	4.954GlyGly: 4.954 ± 0.028	1.684GlyHis: 1.684 ± 0.011	2.772GlyIle: 2.772 ± 0.013	3.898GlyLys: 3.898 ± 0.018	5.861GlyLeu: 5.861 ± 0.023	1.335GlyMet: 1.335 ± 0.009	2.371GlyAsn: 2.371 ± 0.013	4.215GlyPro: 4.215 ± 0.042	2.785GlyGln: 2.785 ± 0.017	3.722GlyArg: 3.722 ± 0.019	5.743GlySer: 5.743 ± 0.025	3.556GlyThr: 3.556 ± 0.016	3.544GlyVal: 3.544 ± 0.015	0.803GlyTrp: 0.803 ± 0.008	1.737GlyTyr: 1.737 ± 0.011	0.002GlyXaa: 0.002 ± 0.0
His	1.317HisAla: 1.317 ± 0.009	0.747HisCys: 0.747 ± 0.007	0.892HisAsp: 0.892 ± 0.006	1.342HisGlu: 1.342 ± 0.008	1.09HisPhe: 1.09 ± 0.008	1.555HisGly: 1.555 ± 0.013	0.908HisHis: 0.908 ± 0.009	1.257HisIle: 1.257 ± 0.008	1.293HisLys: 1.293 ± 0.01	2.953HisLeu: 2.953 ± 0.016	0.592HisMet: 0.592 ± 0.005	0.87HisAsn: 0.87 ± 0.007	1.644HisPro: 1.644 ± 0.011	1.379HisGln: 1.379 ± 0.012	1.59HisArg: 1.59 ± 0.009	2.313HisSer: 2.313 ± 0.013	1.569HisThr: 1.569 ± 0.013	1.49HisVal: 1.49 ± 0.008	0.353HisTrp: 0.353 ± 0.004	0.808HisTyr: 0.808 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.594IleAla: 2.594 ± 0.012	1.091IleCys: 1.091 ± 0.009	2.028IleAsp: 2.028 ± 0.011	2.635IleGlu: 2.635 ± 0.017	1.904IlePhe: 1.904 ± 0.012	2.211IleGly: 2.211 ± 0.011	1.406IleHis: 1.406 ± 0.011	2.43IleIle: 2.43 ± 0.013	2.681IleLys: 2.681 ± 0.019	4.592IleLeu: 4.592 ± 0.018	1.011IleMet: 1.011 ± 0.007	1.862IleAsn: 1.862 ± 0.011	2.63IlePro: 2.63 ± 0.011	2.332IleGln: 2.332 ± 0.014	2.373IleArg: 2.373 ± 0.013	3.744IleSer: 3.744 ± 0.017	2.603IleThr: 2.603 ± 0.021	2.505IleVal: 2.505 ± 0.015	0.511IleTrp: 0.511 ± 0.005	1.39IleTyr: 1.39 ± 0.009	0.001IleXaa: 0.001 ± 0.0
Lys	4.074LysAla: 4.074 ± 0.02	1.201LysCys: 1.201 ± 0.012	3.196LysAsp: 3.196 ± 0.018	5.242LysGlu: 5.242 ± 0.026	1.76LysPhe: 1.76 ± 0.009	3.304LysGly: 3.304 ± 0.022	1.427LysHis: 1.427 ± 0.011	2.852LysIle: 2.852 ± 0.016	4.804LysLys: 4.804 ± 0.024	5.248LysLeu: 5.248 ± 0.024	1.464LysMet: 1.464 ± 0.012	2.438LysAsn: 2.438 ± 0.011	3.177LysPro: 3.177 ± 0.022	2.649LysGln: 2.649 ± 0.016	3.335LysArg: 3.335 ± 0.016	3.932LysSer: 3.932 ± 0.021	3.153LysThr: 3.153 ± 0.016	3.518LysVal: 3.518 ± 0.022	0.622LysTrp: 0.622 ± 0.007	1.599LysTyr: 1.599 ± 0.013	0.001LysXaa: 0.001 ± 0.0
Leu	6.724LeuAla: 6.724 ± 0.029	2.201LeuCys: 2.201 ± 0.015	4.717LeuAsp: 4.717 ± 0.018	7.27LeuGlu: 7.27 ± 0.031	3.354LeuPhe: 3.354 ± 0.017	5.853LeuGly: 5.853 ± 0.022	2.734LeuHis: 2.734 ± 0.013	3.916LeuIle: 3.916 ± 0.016	5.883LeuLys: 5.883 ± 0.025	10.748LeuLeu: 10.748 ± 0.044	2.025LeuMet: 2.025 ± 0.012	3.512LeuAsn: 3.512 ± 0.014	5.974LeuPro: 5.974 ± 0.027	5.835LeuGln: 5.835 ± 0.026	5.864LeuArg: 5.864 ± 0.021	7.931LeuSer: 7.931 ± 0.022	5.115LeuThr: 5.115 ± 0.02	5.477LeuVal: 5.477 ± 0.019	1.146LeuTrp: 1.146 ± 0.008	2.535LeuTyr: 2.535 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	1.92MetAla: 1.92 ± 0.01	0.404MetCys: 0.404 ± 0.005	1.263MetAsp: 1.263 ± 0.007	1.894MetGlu: 1.894 ± 0.012	0.731MetPhe: 0.731 ± 0.007	1.328MetGly: 1.328 ± 0.011	0.473MetHis: 0.473 ± 0.005	0.854MetIle: 0.854 ± 0.006	1.474MetLys: 1.474 ± 0.009	1.994MetLeu: 1.994 ± 0.01	0.574MetMet: 0.574 ± 0.006	0.919MetAsn: 0.919 ± 0.008	1.121MetPro: 1.121 ± 0.011	0.934MetGln: 0.934 ± 0.008	1.055MetArg: 1.055 ± 0.007	1.564MetSer: 1.564 ± 0.009	1.136MetThr: 1.136 ± 0.009	1.386MetVal: 1.386 ± 0.009	0.245MetTrp: 0.245 ± 0.004	0.568MetTyr: 0.568 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.063AsnAla: 2.063 ± 0.011	0.841AsnCys: 0.841 ± 0.007	1.526AsnAsp: 1.526 ± 0.008	2.276AsnGlu: 2.276 ± 0.012	1.479AsnPhe: 1.479 ± 0.01	2.435AsnGly: 2.435 ± 0.017	0.963AsnHis: 0.963 ± 0.007	2.152AsnIle: 2.152 ± 0.011	2.252AsnLys: 2.252 ± 0.013	3.785AsnLeu: 3.785 ± 0.015	0.918AsnMet: 0.918 ± 0.005	1.549AsnAsn: 1.549 ± 0.01	2.172AsnPro: 2.172 ± 0.013	1.677AsnGln: 1.677 ± 0.01	1.844AsnArg: 1.844 ± 0.01	3.132AsnSer: 3.132 ± 0.017	1.971AsnThr: 1.971 ± 0.01	2.204AsnVal: 2.204 ± 0.011	0.455AsnTrp: 0.455 ± 0.005	1.14AsnTyr: 1.14 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.768ProAla: 4.768 ± 0.027	1.143ProCys: 1.143 ± 0.011	2.79ProAsp: 2.79 ± 0.016	4.449ProGlu: 4.449 ± 0.02	1.905ProPhe: 1.905 ± 0.011	5.242ProGly: 5.242 ± 0.054	1.438ProHis: 1.438 ± 0.009	1.926ProIle: 1.926 ± 0.013	2.803ProLys: 2.803 ± 0.021	5.199ProLeu: 5.199 ± 0.02	1.05ProMet: 1.05 ± 0.007	1.818ProAsn: 1.818 ± 0.011	5.964ProPro: 5.964 ± 0.044	2.831ProGln: 2.831 ± 0.017	3.335ProArg: 3.335 ± 0.018	5.642ProSer: 5.642 ± 0.029	3.091ProThr: 3.091 ± 0.018	3.782ProVal: 3.782 ± 0.015	0.707ProTrp: 0.707 ± 0.007	1.545ProTyr: 1.545 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	3.551GlnAla: 3.551 ± 0.017	0.959GlnCys: 0.959 ± 0.009	2.345GlnAsp: 2.345 ± 0.012	3.992GlnGlu: 3.992 ± 0.021	1.386GlnPhe: 1.386 ± 0.008	2.855GlnGly: 2.855 ± 0.016	1.313GlnHis: 1.313 ± 0.01	2.003GlnIle: 2.003 ± 0.01	3.028GlnLys: 3.028 ± 0.018	4.748GlnLeu: 4.748 ± 0.022	1.126GlnMet: 1.126 ± 0.008	1.876GlnAsn: 1.876 ± 0.01	2.813GlnPro: 2.813 ± 0.018	3.108GlnGln: 3.108 ± 0.027	2.982GlnArg: 2.982 ± 0.015	3.129GlnSer: 3.129 ± 0.015	2.305GlnThr: 2.305 ± 0.012	2.825GlnVal: 2.825 ± 0.013	0.553GlnTrp: 0.553 ± 0.005	1.153GlnTyr: 1.153 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.767ArgAla: 3.767 ± 0.018	1.219ArgCys: 1.219 ± 0.012	2.75ArgAsp: 2.75 ± 0.012	3.985ArgGlu: 3.985 ± 0.018	1.842ArgPhe: 1.842 ± 0.009	3.6ArgGly: 3.6 ± 0.024	1.549ArgHis: 1.549 ± 0.011	2.457ArgIle: 2.457 ± 0.013	3.694ArgLys: 3.694 ± 0.016	5.384ArgLeu: 5.384 ± 0.022	1.215ArgMet: 1.215 ± 0.007	2.142ArgAsn: 2.142 ± 0.011	3.185ArgPro: 3.185 ± 0.016	2.612ArgGln: 2.612 ± 0.012	4.269ArgArg: 4.269 ± 0.022	4.213ArgSer: 4.213 ± 0.025	2.81ArgThr: 2.81 ± 0.012	3.153ArgVal: 3.153 ± 0.017	0.713ArgTrp: 0.713 ± 0.007	1.434ArgTyr: 1.434 ± 0.009	0.001ArgXaa: 0.001 ± 0.0
Ser	5.248SerAla: 5.248 ± 0.018	1.859SerCys: 1.859 ± 0.013	3.881SerAsp: 3.881 ± 0.021	5.195SerGlu: 5.195 ± 0.021	3.043SerPhe: 3.043 ± 0.013	5.579SerGly: 5.579 ± 0.028	2.135SerHis: 2.135 ± 0.014	3.219SerIle: 3.219 ± 0.014	4.094SerLys: 4.094 ± 0.019	8.179SerLeu: 8.179 ± 0.025	1.624SerMet: 1.624 ± 0.009	2.707SerAsn: 2.707 ± 0.012	5.921SerPro: 5.921 ± 0.035	3.882SerGln: 3.882 ± 0.015	4.522SerArg: 4.522 ± 0.024	9.275SerSer: 9.275 ± 0.046	4.42SerThr: 4.42 ± 0.02	4.817SerVal: 4.817 ± 0.017	1.089SerTrp: 1.089 ± 0.008	2.078SerTyr: 2.078 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	3.745ThrAla: 3.745 ± 0.016	1.307ThrCys: 1.307 ± 0.011	2.469ThrAsp: 2.469 ± 0.013	3.558ThrGlu: 3.558 ± 0.018	2.083ThrPhe: 2.083 ± 0.011	3.589ThrGly: 3.589 ± 0.019	1.343ThrHis: 1.343 ± 0.008	2.407ThrIle: 2.407 ± 0.015	2.699ThrLys: 2.699 ± 0.018	5.296ThrLeu: 5.296 ± 0.017	1.119ThrMet: 1.119 ± 0.007	1.761ThrAsn: 1.761 ± 0.01	3.582ThrPro: 3.582 ± 0.019	2.308ThrGln: 2.308 ± 0.012	2.454ThrArg: 2.454 ± 0.012	4.603ThrSer: 4.603 ± 0.021	3.035ThrThr: 3.035 ± 0.019	3.833ThrVal: 3.833 ± 0.022	0.71ThrTrp: 0.71 ± 0.008	1.42ThrTyr: 1.42 ± 0.008	0.001ThrXaa: 0.001 ± 0.0
Val	4.258ValAla: 4.258 ± 0.017	1.423ValCys: 1.423 ± 0.009	2.961ValAsp: 2.961 ± 0.015	3.898ValGlu: 3.898 ± 0.021	2.373ValPhe: 2.373 ± 0.011	3.372ValGly: 3.372 ± 0.015	1.575ValHis: 1.575 ± 0.01	2.925ValIle: 2.925 ± 0.017	3.434ValLys: 3.434 ± 0.023	6.129ValLeu: 6.129 ± 0.02	1.325ValMet: 1.325 ± 0.008	2.269ValAsn: 2.269 ± 0.012	3.597ValPro: 3.597 ± 0.019	2.73ValGln: 2.73 ± 0.013	3.014ValArg: 3.014 ± 0.013	4.837ValSer: 4.837 ± 0.018	3.755ValThr: 3.755 ± 0.027	3.962ValVal: 3.962 ± 0.02	0.718ValTrp: 0.718 ± 0.006	1.603ValTyr: 1.603 ± 0.009	0.001ValXaa: 0.001 ± 0.0
Trp	0.8TrpAla: 0.8 ± 0.007	0.249TrpCys: 0.249 ± 0.003	0.652TrpAsp: 0.652 ± 0.007	0.834TrpGlu: 0.834 ± 0.006	0.444TrpPhe: 0.444 ± 0.005	0.738TrpGly: 0.738 ± 0.007	0.315TrpHis: 0.315 ± 0.004	0.546TrpIle: 0.546 ± 0.006	0.83TrpLys: 0.83 ± 0.007	1.225TrpLeu: 1.225 ± 0.01	0.322TrpMet: 0.322 ± 0.004	0.54TrpAsn: 0.54 ± 0.005	0.542TrpPro: 0.542 ± 0.005	0.548TrpGln: 0.548 ± 0.005	0.73TrpArg: 0.73 ± 0.006	0.89TrpSer: 0.89 ± 0.007	0.679TrpThr: 0.679 ± 0.007	0.709TrpVal: 0.709 ± 0.006	0.203TrpTrp: 0.203 ± 0.003	0.34TrpTyr: 0.34 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.378TyrAla: 1.378 ± 0.008	0.676TyrCys: 0.676 ± 0.007	1.289TyrAsp: 1.289 ± 0.009	1.736TyrGlu: 1.736 ± 0.01	1.21TyrPhe: 1.21 ± 0.008	1.652TyrGly: 1.652 ± 0.01	0.75TyrHis: 0.75 ± 0.006	1.389TyrIle: 1.389 ± 0.01	1.542TyrLys: 1.542 ± 0.018	2.639TyrLeu: 2.639 ± 0.013	0.599TyrMet: 0.599 ± 0.006	1.104TyrAsn: 1.104 ± 0.008	1.282TyrPro: 1.282 ± 0.009	1.283TyrGln: 1.283 ± 0.008	1.612TyrArg: 1.612 ± 0.011	2.176TyrSer: 2.176 ± 0.011	1.467TyrThr: 1.467 ± 0.01	1.568TyrVal: 1.568 ± 0.011	0.365TyrTrp: 0.365 ± 0.006	0.934TyrTyr: 0.934 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.294XaaXaa: 0.294 ± 0.041

Statistics based on 44727 proteins (23270229 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---