Amino acid dipepetide frequency for Cladophialophora carrionii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.657AlaAla: 9.657 ± 0.054	1.048AlaCys: 1.048 ± 0.015	4.585AlaAsp: 4.585 ± 0.029	5.461AlaGlu: 5.461 ± 0.044	3.181AlaPhe: 3.181 ± 0.026	6.223AlaGly: 6.223 ± 0.039	1.933AlaHis: 1.933 ± 0.019	4.163AlaIle: 4.163 ± 0.03	4.138AlaLys: 4.138 ± 0.034	7.846AlaLeu: 7.846 ± 0.051	2.009AlaMet: 2.009 ± 0.022	2.993AlaAsn: 2.993 ± 0.024	4.976AlaPro: 4.976 ± 0.048	3.798AlaGln: 3.798 ± 0.03	5.51AlaArg: 5.51 ± 0.04	7.486AlaSer: 7.486 ± 0.046	5.666AlaThr: 5.666 ± 0.04	5.646AlaVal: 5.646 ± 0.035	1.184AlaTrp: 1.184 ± 0.016	2.196AlaTyr: 2.196 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.956CysAla: 0.956 ± 0.016	0.229CysCys: 0.229 ± 0.007	0.612CysAsp: 0.612 ± 0.011	0.558CysGlu: 0.558 ± 0.012	0.509CysPhe: 0.509 ± 0.011	0.86CysGly: 0.86 ± 0.016	0.324CysHis: 0.324 ± 0.009	0.627CysIle: 0.627 ± 0.011	0.456CysLys: 0.456 ± 0.01	1.21CysLeu: 1.21 ± 0.016	0.247CysMet: 0.247 ± 0.007	0.374CysAsn: 0.374 ± 0.008	0.63CysPro: 0.63 ± 0.012	0.422CysGln: 0.422 ± 0.009	0.746CysArg: 0.746 ± 0.013	0.82CysSer: 0.82 ± 0.015	0.645CysThr: 0.645 ± 0.011	0.765CysVal: 0.765 ± 0.014	0.206CysTrp: 0.206 ± 0.007	0.339CysTyr: 0.339 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.975AspAla: 4.975 ± 0.031	0.595AspCys: 0.595 ± 0.013	4.45AspAsp: 4.45 ± 0.044	4.633AspGlu: 4.633 ± 0.041	2.218AspPhe: 2.218 ± 0.02	4.152AspGly: 4.152 ± 0.031	1.361AspHis: 1.361 ± 0.017	2.82AspIle: 2.82 ± 0.025	2.344AspLys: 2.344 ± 0.022	5.149AspLeu: 5.149 ± 0.037	1.275AspMet: 1.275 ± 0.016	1.772AspAsn: 1.772 ± 0.019	3.48AspPro: 3.48 ± 0.028	2.027AspGln: 2.027 ± 0.023	3.268AspArg: 3.268 ± 0.028	3.951AspSer: 3.951 ± 0.028	3.057AspThr: 3.057 ± 0.027	3.891AspVal: 3.891 ± 0.034	0.886AspTrp: 0.886 ± 0.012	1.516AspTyr: 1.516 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.553GluAla: 5.553 ± 0.043	0.575GluCys: 0.575 ± 0.011	4.284GluAsp: 4.284 ± 0.034	5.249GluGlu: 5.249 ± 0.052	1.822GluPhe: 1.822 ± 0.019	3.768GluGly: 3.768 ± 0.029	1.496GluHis: 1.496 ± 0.019	2.871GluIle: 2.871 ± 0.024	3.584GluLys: 3.584 ± 0.034	5.065GluLeu: 5.065 ± 0.036	1.437GluMet: 1.437 ± 0.017	2.079GluAsn: 2.079 ± 0.018	2.827GluPro: 2.827 ± 0.032	2.674GluGln: 2.674 ± 0.029	4.049GluArg: 4.049 ± 0.034	4.138GluSer: 4.138 ± 0.031	3.413GluThr: 3.413 ± 0.03	3.65GluVal: 3.65 ± 0.026	0.86GluTrp: 0.86 ± 0.014	1.573GluTyr: 1.573 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.1PheAla: 3.1 ± 0.028	0.526PheCys: 0.526 ± 0.01	2.298PheAsp: 2.298 ± 0.022	2.121PheGlu: 2.121 ± 0.021	1.559PhePhe: 1.559 ± 0.018	2.817PheGly: 2.817 ± 0.031	0.874PheHis: 0.874 ± 0.013	1.627PheIle: 1.627 ± 0.019	1.394PheLys: 1.394 ± 0.017	3.374PheLeu: 3.374 ± 0.028	0.75PheMet: 0.75 ± 0.012	1.32PheAsn: 1.32 ± 0.016	1.913PhePro: 1.913 ± 0.02	1.365PheGln: 1.365 ± 0.017	1.964PheArg: 1.964 ± 0.022	2.821PheSer: 2.821 ± 0.024	2.035PheThr: 2.035 ± 0.018	2.399PheVal: 2.399 ± 0.023	0.616PheTrp: 0.616 ± 0.011	1.04PheTyr: 1.04 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.505GlyAla: 5.505 ± 0.035	0.803GlyCys: 0.803 ± 0.015	3.694GlyAsp: 3.694 ± 0.03	3.689GlyGlu: 3.689 ± 0.027	2.758GlyPhe: 2.758 ± 0.029	6.02GlyGly: 6.02 ± 0.06	1.797GlyHis: 1.797 ± 0.021	3.321GlyIle: 3.321 ± 0.029	3.323GlyLys: 3.323 ± 0.026	6.112GlyLeu: 6.112 ± 0.039	1.671GlyMet: 1.671 ± 0.018	2.386GlyAsn: 2.386 ± 0.025	3.552GlyPro: 3.552 ± 0.035	2.731GlyGln: 2.731 ± 0.026	4.426GlyArg: 4.426 ± 0.031	5.586GlySer: 5.586 ± 0.035	4.139GlyThr: 4.139 ± 0.033	4.485GlyVal: 4.485 ± 0.032	1.157GlyTrp: 1.157 ± 0.017	2.077GlyTyr: 2.077 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.094HisAla: 2.094 ± 0.022	0.307HisCys: 0.307 ± 0.009	1.501HisAsp: 1.501 ± 0.019	1.45HisGlu: 1.45 ± 0.02	0.944HisPhe: 0.944 ± 0.015	1.889HisGly: 1.889 ± 0.019	0.921HisHis: 0.921 ± 0.018	1.17HisIle: 1.17 ± 0.014	0.935HisLys: 0.935 ± 0.013	2.266HisLeu: 2.266 ± 0.022	0.487HisMet: 0.487 ± 0.009	0.829HisAsn: 0.829 ± 0.014	1.738HisPro: 1.738 ± 0.018	1.042HisGln: 1.042 ± 0.015	1.598HisArg: 1.598 ± 0.02	1.854HisSer: 1.854 ± 0.022	1.306HisThr: 1.306 ± 0.015	1.571HisVal: 1.571 ± 0.019	0.344HisTrp: 0.344 ± 0.008	0.68HisTyr: 0.68 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.072IleAla: 4.072 ± 0.028	0.704IleCys: 0.704 ± 0.013	2.746IleAsp: 2.746 ± 0.022	2.65IleGlu: 2.65 ± 0.022	1.817IlePhe: 1.817 ± 0.022	3.023IleGly: 3.023 ± 0.029	1.139IleHis: 1.139 ± 0.015	2.245IleIle: 2.245 ± 0.023	2.001IleLys: 2.001 ± 0.023	4.382IleLeu: 4.382 ± 0.032	0.933IleMet: 0.933 ± 0.014	1.657IleAsn: 1.657 ± 0.019	2.915IlePro: 2.915 ± 0.024	1.794IleGln: 1.794 ± 0.018	2.683IleArg: 2.683 ± 0.025	3.586IleSer: 3.586 ± 0.031	2.68IleThr: 2.68 ± 0.024	3.039IleVal: 3.039 ± 0.027	0.694IleTrp: 0.694 ± 0.01	1.312IleTyr: 1.312 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.222LysAla: 4.222 ± 0.037	0.467LysCys: 0.467 ± 0.01	2.774LysAsp: 2.774 ± 0.025	3.217LysGlu: 3.217 ± 0.032	1.39LysPhe: 1.39 ± 0.014	2.863LysGly: 2.863 ± 0.029	1.185LysHis: 1.185 ± 0.015	2.163LysIle: 2.163 ± 0.023	3.108LysLys: 3.108 ± 0.047	3.876LysLeu: 3.876 ± 0.035	0.993LysMet: 0.993 ± 0.015	1.577LysAsn: 1.577 ± 0.021	2.719LysPro: 2.719 ± 0.025	1.911LysGln: 1.911 ± 0.023	3.422LysArg: 3.422 ± 0.033	3.347LysSer: 3.347 ± 0.031	2.708LysThr: 2.708 ± 0.023	2.81LysVal: 2.81 ± 0.026	0.653LysTrp: 0.653 ± 0.011	1.333LysTyr: 1.333 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.065LeuAla: 8.065 ± 0.035	1.187LeuCys: 1.187 ± 0.017	5.184LeuAsp: 5.184 ± 0.036	5.424LeuGlu: 5.424 ± 0.041	3.199LeuPhe: 3.199 ± 0.028	5.929LeuGly: 5.929 ± 0.037	2.238LeuHis: 2.238 ± 0.022	3.698LeuIle: 3.698 ± 0.028	4.108LeuLys: 4.108 ± 0.034	8.185LeuLeu: 8.185 ± 0.051	1.768LeuMet: 1.768 ± 0.018	3.063LeuAsn: 3.063 ± 0.027	5.552LeuPro: 5.552 ± 0.038	3.839LeuGln: 3.839 ± 0.028	5.871LeuArg: 5.871 ± 0.042	7.105LeuSer: 7.105 ± 0.045	4.888LeuThr: 4.888 ± 0.03	5.448LeuVal: 5.448 ± 0.038	1.192LeuTrp: 1.192 ± 0.015	2.273LeuTyr: 2.273 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.314MetAla: 2.314 ± 0.02	0.247MetCys: 0.247 ± 0.008	1.207MetAsp: 1.207 ± 0.017	1.151MetGlu: 1.151 ± 0.016	0.717MetPhe: 0.717 ± 0.011	1.437MetGly: 1.437 ± 0.02	0.508MetHis: 0.508 ± 0.01	0.932MetIle: 0.932 ± 0.015	0.941MetLys: 0.941 ± 0.014	1.868MetLeu: 1.868 ± 0.017	0.545MetMet: 0.545 ± 0.011	0.755MetAsn: 0.755 ± 0.014	1.33MetPro: 1.33 ± 0.016	0.882MetGln: 0.882 ± 0.013	1.264MetArg: 1.264 ± 0.016	1.887MetSer: 1.887 ± 0.022	1.323MetThr: 1.323 ± 0.017	1.284MetVal: 1.284 ± 0.015	0.254MetTrp: 0.254 ± 0.006	0.519MetTyr: 0.519 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.173AsnAla: 3.173 ± 0.025	0.376AsnCys: 0.376 ± 0.009	1.904AsnAsp: 1.904 ± 0.019	1.893AsnGlu: 1.893 ± 0.022	1.269AsnPhe: 1.269 ± 0.016	2.907AsnGly: 2.907 ± 0.03	0.855AsnHis: 0.855 ± 0.013	1.843AsnIle: 1.843 ± 0.018	1.424AsnLys: 1.424 ± 0.018	3.091AsnLeu: 3.091 ± 0.026	0.762AsnMet: 0.762 ± 0.013	1.35AsnAsn: 1.35 ± 0.025	2.371AsnPro: 2.371 ± 0.021	1.279AsnGln: 1.279 ± 0.017	1.879AsnArg: 1.879 ± 0.02	2.467AsnSer: 2.467 ± 0.023	2.075AsnThr: 2.075 ± 0.021	2.307AsnVal: 2.307 ± 0.022	0.51AsnTrp: 0.51 ± 0.01	0.952AsnTyr: 0.952 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.727ProAla: 5.727 ± 0.046	0.497ProCys: 0.497 ± 0.011	3.363ProAsp: 3.363 ± 0.027	3.814ProGlu: 3.814 ± 0.034	2.062ProPhe: 2.062 ± 0.024	4.174ProGly: 4.174 ± 0.034	1.402ProHis: 1.402 ± 0.018	2.416ProIle: 2.416 ± 0.024	2.585ProLys: 2.585 ± 0.029	4.815ProLeu: 4.815 ± 0.034	1.101ProMet: 1.101 ± 0.015	2.108ProAsn: 2.108 ± 0.02	5.588ProPro: 5.588 ± 0.072	2.693ProGln: 2.693 ± 0.027	3.696ProArg: 3.696 ± 0.033	6.155ProSer: 6.155 ± 0.048	4.199ProThr: 4.199 ± 0.037	3.744ProVal: 3.744 ± 0.028	0.738ProTrp: 0.738 ± 0.013	1.503ProTyr: 1.503 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.811GlnAla: 3.811 ± 0.028	0.419GlnCys: 0.419 ± 0.01	2.187GlnAsp: 2.187 ± 0.021	2.488GlnGlu: 2.488 ± 0.026	1.28GlnPhe: 1.28 ± 0.016	2.56GlnGly: 2.56 ± 0.025	1.217GlnHis: 1.217 ± 0.016	1.9GlnIle: 1.9 ± 0.019	2.025GlnLys: 2.025 ± 0.025	3.447GlnLeu: 3.447 ± 0.028	0.9GlnMet: 0.9 ± 0.015	1.533GlnAsn: 1.533 ± 0.02	2.772GlnPro: 2.772 ± 0.035	2.594GlnGln: 2.594 ± 0.038	2.834GlnArg: 2.834 ± 0.026	3.315GlnSer: 3.315 ± 0.03	2.436GlnThr: 2.436 ± 0.02	2.23GlnVal: 2.23 ± 0.02	0.565GlnTrp: 0.565 ± 0.011	1.191GlnTyr: 1.191 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.096ArgAla: 5.096 ± 0.036	0.684ArgCys: 0.684 ± 0.013	3.576ArgAsp: 3.576 ± 0.032	3.907ArgGlu: 3.907 ± 0.04	2.056ArgPhe: 2.056 ± 0.019	3.856ArgGly: 3.856 ± 0.034	1.763ArgHis: 1.763 ± 0.017	2.787ArgIle: 2.787 ± 0.026	3.571ArgLys: 3.571 ± 0.031	5.701ArgLeu: 5.701 ± 0.037	1.351ArgMet: 1.351 ± 0.019	2.217ArgAsn: 2.217 ± 0.021	3.933ArgPro: 3.933 ± 0.034	2.894ArgGln: 2.894 ± 0.027	5.567ArgArg: 5.567 ± 0.046	5.006ArgSer: 5.006 ± 0.039	3.54ArgThr: 3.54 ± 0.027	3.456ArgVal: 3.456 ± 0.027	0.951ArgTrp: 0.951 ± 0.015	1.694ArgTyr: 1.694 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.918SerAla: 6.918 ± 0.039	0.817SerCys: 0.817 ± 0.014	4.145SerAsp: 4.145 ± 0.034	3.995SerGlu: 3.995 ± 0.032	2.832SerPhe: 2.832 ± 0.023	5.47SerGly: 5.47 ± 0.036	1.967SerHis: 1.967 ± 0.021	3.737SerIle: 3.737 ± 0.03	3.539SerLys: 3.539 ± 0.029	7.005SerLeu: 7.005 ± 0.043	1.693SerMet: 1.693 ± 0.017	2.81SerAsn: 2.81 ± 0.024	5.781SerPro: 5.781 ± 0.054	3.373SerGln: 3.373 ± 0.031	5.23SerArg: 5.23 ± 0.043	8.791SerSer: 8.791 ± 0.088	5.85SerThr: 5.85 ± 0.052	4.529SerVal: 4.529 ± 0.037	1.088SerTrp: 1.088 ± 0.015	1.951SerTyr: 1.951 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.599ThrAla: 5.599 ± 0.039	0.685ThrCys: 0.685 ± 0.014	2.96ThrAsp: 2.96 ± 0.024	3.083ThrGlu: 3.083 ± 0.024	2.219ThrPhe: 2.219 ± 0.022	4.271ThrGly: 4.271 ± 0.034	1.338ThrHis: 1.338 ± 0.015	2.961ThrIle: 2.961 ± 0.027	2.571ThrLys: 2.571 ± 0.023	5.194ThrLeu: 5.194 ± 0.029	1.198ThrMet: 1.198 ± 0.016	2.103ThrAsn: 2.103 ± 0.022	4.47ThrPro: 4.47 ± 0.039	2.194ThrGln: 2.194 ± 0.022	3.328ThrArg: 3.328 ± 0.027	5.625ThrSer: 5.625 ± 0.05	4.658ThrThr: 4.658 ± 0.049	3.819ThrVal: 3.819 ± 0.032	0.837ThrTrp: 0.837 ± 0.013	1.567ThrTyr: 1.567 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.553ValAla: 5.553 ± 0.034	0.792ValCys: 0.792 ± 0.014	3.883ValAsp: 3.883 ± 0.029	3.917ValGlu: 3.917 ± 0.03	2.398ValPhe: 2.398 ± 0.024	4.106ValGly: 4.106 ± 0.032	1.474ValHis: 1.474 ± 0.019	2.775ValIle: 2.775 ± 0.025	2.888ValLys: 2.888 ± 0.029	5.672ValLeu: 5.672 ± 0.039	1.316ValMet: 1.316 ± 0.016	2.159ValAsn: 2.159 ± 0.021	3.742ValPro: 3.742 ± 0.029	2.493ValGln: 2.493 ± 0.023	3.683ValArg: 3.683 ± 0.031	4.631ValSer: 4.631 ± 0.033	3.54ValThr: 3.54 ± 0.033	4.458ValVal: 4.458 ± 0.034	0.873ValTrp: 0.873 ± 0.014	1.635ValTyr: 1.635 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.11TrpAla: 1.11 ± 0.013	0.192TrpCys: 0.192 ± 0.006	0.836TrpAsp: 0.836 ± 0.015	0.813TrpGlu: 0.813 ± 0.012	0.535TrpPhe: 0.535 ± 0.01	0.868TrpGly: 0.868 ± 0.014	0.377TrpHis: 0.377 ± 0.009	0.743TrpIle: 0.743 ± 0.013	0.764TrpLys: 0.764 ± 0.013	1.364TrpLeu: 1.364 ± 0.019	0.357TrpMet: 0.357 ± 0.009	0.564TrpAsn: 0.564 ± 0.011	0.615TrpPro: 0.615 ± 0.011	0.589TrpGln: 0.589 ± 0.01	0.999TrpArg: 0.999 ± 0.014	1.059TrpSer: 1.059 ± 0.016	0.967TrpThr: 0.967 ± 0.015	0.843TrpVal: 0.843 ± 0.015	0.276TrpTrp: 0.276 ± 0.007	0.438TrpTyr: 0.438 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.199TyrAla: 2.199 ± 0.022	0.384TyrCys: 0.384 ± 0.01	1.631TyrAsp: 1.631 ± 0.021	1.452TyrGlu: 1.452 ± 0.02	1.148TyrPhe: 1.148 ± 0.016	2.039TyrGly: 2.039 ± 0.021	0.756TyrHis: 0.756 ± 0.012	1.272TyrIle: 1.272 ± 0.016	1.037TyrLys: 1.037 ± 0.015	2.591TyrLeu: 2.591 ± 0.023	0.574TyrMet: 0.574 ± 0.011	1.041TyrAsn: 1.041 ± 0.013	1.476TyrPro: 1.476 ± 0.018	1.111TyrGln: 1.111 ± 0.016	1.591TyrArg: 1.591 ± 0.019	1.893TyrSer: 1.893 ± 0.02	1.557TyrThr: 1.557 ± 0.02	1.613TyrVal: 1.613 ± 0.017	0.424TyrTrp: 0.424 ± 0.01	0.848TyrTyr: 0.848 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11181 proteins (5263867 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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