Amino acid dipepetide frequency for Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.979AlaAla: 8.979 ± 0.063	1.087AlaCys: 1.087 ± 0.017	4.347AlaAsp: 4.347 ± 0.032	5.282AlaGlu: 5.282 ± 0.053	3.179AlaPhe: 3.179 ± 0.03	5.779AlaGly: 5.779 ± 0.036	1.796AlaHis: 1.796 ± 0.018	4.229AlaIle: 4.229 ± 0.032	3.93AlaLys: 3.93 ± 0.034	7.872AlaLeu: 7.872 ± 0.048	1.939AlaMet: 1.939 ± 0.02	2.94AlaAsn: 2.94 ± 0.025	4.656AlaPro: 4.656 ± 0.043	3.436AlaGln: 3.436 ± 0.029	5.111AlaArg: 5.111 ± 0.032	7.363AlaSer: 7.363 ± 0.048	5.244AlaThr: 5.244 ± 0.034	5.56AlaVal: 5.56 ± 0.038	1.155AlaTrp: 1.155 ± 0.018	2.175AlaTyr: 2.175 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.967CysAla: 0.967 ± 0.014	0.263CysCys: 0.263 ± 0.008	0.684CysAsp: 0.684 ± 0.011	0.613CysGlu: 0.613 ± 0.012	0.551CysPhe: 0.551 ± 0.011	0.951CysGly: 0.951 ± 0.016	0.346CysHis: 0.346 ± 0.009	0.696CysIle: 0.696 ± 0.013	0.508CysLys: 0.508 ± 0.011	1.387CysLeu: 1.387 ± 0.018	0.277CysMet: 0.277 ± 0.008	0.446CysAsn: 0.446 ± 0.01	0.701CysPro: 0.701 ± 0.014	0.471CysGln: 0.471 ± 0.011	0.853CysArg: 0.853 ± 0.015	0.999CysSer: 0.999 ± 0.015	0.697CysThr: 0.697 ± 0.013	0.831CysVal: 0.831 ± 0.015	0.207CysTrp: 0.207 ± 0.007	0.36CysTyr: 0.36 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.641AspAla: 4.641 ± 0.038	0.644AspCys: 0.644 ± 0.013	3.821AspAsp: 3.821 ± 0.044	4.301AspGlu: 4.301 ± 0.04	2.144AspPhe: 2.144 ± 0.021	3.905AspGly: 3.905 ± 0.031	1.267AspHis: 1.267 ± 0.017	3.002AspIle: 3.002 ± 0.025	2.209AspLys: 2.209 ± 0.024	5.105AspLeu: 5.105 ± 0.036	1.204AspMet: 1.204 ± 0.018	1.806AspAsn: 1.806 ± 0.021	3.371AspPro: 3.371 ± 0.026	1.91AspGln: 1.91 ± 0.021	3.186AspArg: 3.186 ± 0.029	4.119AspSer: 4.119 ± 0.032	2.862AspThr: 2.862 ± 0.025	3.618AspVal: 3.618 ± 0.025	0.849AspTrp: 0.849 ± 0.014	1.614AspTyr: 1.614 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.27GluAla: 5.27 ± 0.043	0.626GluCys: 0.626 ± 0.012	4.049GluAsp: 4.049 ± 0.04	5.444GluGlu: 5.444 ± 0.06	1.928GluPhe: 1.928 ± 0.022	3.657GluGly: 3.657 ± 0.028	1.385GluHis: 1.385 ± 0.018	3.113GluIle: 3.113 ± 0.029	3.596GluLys: 3.596 ± 0.034	5.245GluLeu: 5.245 ± 0.045	1.434GluMet: 1.434 ± 0.02	2.292GluAsn: 2.292 ± 0.024	2.831GluPro: 2.831 ± 0.058	2.555GluGln: 2.555 ± 0.028	4.071GluArg: 4.071 ± 0.04	4.388GluSer: 4.388 ± 0.037	3.517GluThr: 3.517 ± 0.032	3.531GluVal: 3.531 ± 0.027	0.864GluTrp: 0.864 ± 0.015	1.695GluTyr: 1.695 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.075PheAla: 3.075 ± 0.028	0.588PheCys: 0.588 ± 0.012	2.227PheAsp: 2.227 ± 0.024	2.09PheGlu: 2.09 ± 0.024	1.679PhePhe: 1.679 ± 0.024	2.746PheGly: 2.746 ± 0.035	0.936PheHis: 0.936 ± 0.014	1.804PheIle: 1.804 ± 0.021	1.417PheLys: 1.417 ± 0.018	3.644PheLeu: 3.644 ± 0.028	0.772PheMet: 0.772 ± 0.013	1.384PheAsn: 1.384 ± 0.016	2.019PhePro: 2.019 ± 0.024	1.407PheGln: 1.407 ± 0.022	2.065PheArg: 2.065 ± 0.024	3.073PheSer: 3.073 ± 0.026	2.075PheThr: 2.075 ± 0.022	2.412PheVal: 2.412 ± 0.025	0.646PheTrp: 0.646 ± 0.013	1.136PheTyr: 1.136 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.241GlyAla: 5.241 ± 0.04	0.906GlyCys: 0.906 ± 0.015	3.504GlyAsp: 3.504 ± 0.032	3.567GlyGlu: 3.567 ± 0.029	2.733GlyPhe: 2.733 ± 0.028	5.258GlyGly: 5.258 ± 0.051	1.67GlyHis: 1.67 ± 0.02	3.474GlyIle: 3.474 ± 0.033	3.307GlyLys: 3.307 ± 0.03	6.138GlyLeu: 6.138 ± 0.042	1.533GlyMet: 1.533 ± 0.018	2.4GlyAsn: 2.4 ± 0.025	3.341GlyPro: 3.341 ± 0.029	2.606GlyGln: 2.606 ± 0.027	4.151GlyArg: 4.151 ± 0.031	5.621GlySer: 5.621 ± 0.041	3.887GlyThr: 3.887 ± 0.03	4.365GlyVal: 4.365 ± 0.035	1.161GlyTrp: 1.161 ± 0.018	2.127GlyTyr: 2.127 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.872HisAla: 1.872 ± 0.02	0.342HisCys: 0.342 ± 0.008	1.308HisAsp: 1.308 ± 0.015	1.294HisGlu: 1.294 ± 0.018	0.931HisPhe: 0.931 ± 0.014	1.74HisGly: 1.74 ± 0.022	0.867HisHis: 0.867 ± 0.018	1.21HisIle: 1.21 ± 0.017	0.855HisLys: 0.855 ± 0.013	2.347HisLeu: 2.347 ± 0.025	0.482HisMet: 0.482 ± 0.01	0.836HisAsn: 0.836 ± 0.015	1.738HisPro: 1.738 ± 0.018	1.01HisGln: 1.01 ± 0.016	1.66HisArg: 1.66 ± 0.021	1.936HisSer: 1.936 ± 0.023	1.28HisThr: 1.28 ± 0.018	1.403HisVal: 1.403 ± 0.016	0.349HisTrp: 0.349 ± 0.009	0.716HisTyr: 0.716 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.228IleAla: 4.228 ± 0.032	0.787IleCys: 0.787 ± 0.013	2.825IleAsp: 2.825 ± 0.028	2.836IleGlu: 2.836 ± 0.028	1.995IlePhe: 1.995 ± 0.021	3.127IleGly: 3.127 ± 0.028	1.229IleHis: 1.229 ± 0.014	2.54IleIle: 2.54 ± 0.03	2.063IleLys: 2.063 ± 0.025	4.766IleLeu: 4.766 ± 0.034	0.967IleMet: 0.967 ± 0.015	1.765IleAsn: 1.765 ± 0.02	3.157IlePro: 3.157 ± 0.026	1.908IleGln: 1.908 ± 0.022	2.945IleArg: 2.945 ± 0.024	3.893IleSer: 3.893 ± 0.03	2.759IleThr: 2.759 ± 0.025	3.219IleVal: 3.219 ± 0.03	0.719IleTrp: 0.719 ± 0.013	1.477IleTyr: 1.477 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.055LysAla: 4.055 ± 0.037	0.498LysCys: 0.498 ± 0.011	2.645LysAsp: 2.645 ± 0.027	3.303LysGlu: 3.303 ± 0.034	1.38LysPhe: 1.38 ± 0.019	2.851LysGly: 2.851 ± 0.027	1.101LysHis: 1.101 ± 0.016	2.19LysIle: 2.19 ± 0.024	3.1LysLys: 3.1 ± 0.04	3.969LysLeu: 3.969 ± 0.032	0.934LysMet: 0.934 ± 0.014	1.679LysAsn: 1.679 ± 0.019	2.615LysPro: 2.615 ± 0.031	1.837LysGln: 1.837 ± 0.021	3.395LysArg: 3.395 ± 0.031	3.339LysSer: 3.339 ± 0.032	2.633LysThr: 2.633 ± 0.026	2.746LysVal: 2.746 ± 0.027	0.627LysTrp: 0.627 ± 0.012	1.383LysTyr: 1.383 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.052LeuAla: 8.052 ± 0.045	1.293LeuCys: 1.293 ± 0.021	5.18LeuAsp: 5.18 ± 0.034	5.556LeuGlu: 5.556 ± 0.049	3.399LeuPhe: 3.399 ± 0.032	5.958LeuGly: 5.958 ± 0.037	2.327LeuHis: 2.327 ± 0.024	4.093LeuIle: 4.093 ± 0.037	4.116LeuLys: 4.116 ± 0.038	8.786LeuLeu: 8.786 ± 0.07	1.814LeuMet: 1.814 ± 0.019	3.213LeuAsn: 3.213 ± 0.025	5.586LeuPro: 5.586 ± 0.041	3.956LeuGln: 3.956 ± 0.038	6.12LeuArg: 6.12 ± 0.042	7.771LeuSer: 7.771 ± 0.046	4.944LeuThr: 4.944 ± 0.04	5.574LeuVal: 5.574 ± 0.037	1.228LeuTrp: 1.228 ± 0.017	2.455LeuTyr: 2.455 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.137MetAla: 2.137 ± 0.02	0.244MetCys: 0.244 ± 0.007	1.205MetAsp: 1.205 ± 0.016	1.284MetGlu: 1.284 ± 0.018	0.719MetPhe: 0.719 ± 0.014	1.385MetGly: 1.385 ± 0.018	0.462MetHis: 0.462 ± 0.01	1.022MetIle: 1.022 ± 0.016	0.98MetLys: 0.98 ± 0.014	1.863MetLeu: 1.863 ± 0.024	0.562MetMet: 0.562 ± 0.012	0.787MetAsn: 0.787 ± 0.015	1.174MetPro: 1.174 ± 0.019	0.864MetGln: 0.864 ± 0.014	1.285MetArg: 1.285 ± 0.017	1.806MetSer: 1.806 ± 0.021	1.3MetThr: 1.3 ± 0.017	1.328MetVal: 1.328 ± 0.016	0.254MetTrp: 0.254 ± 0.007	0.526MetTyr: 0.526 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.154AsnAla: 3.154 ± 0.032	0.467AsnCys: 0.467 ± 0.011	1.893AsnAsp: 1.893 ± 0.019	2.0AsnGlu: 2.0 ± 0.019	1.334AsnPhe: 1.334 ± 0.018	2.91AsnGly: 2.91 ± 0.023	0.867AsnHis: 0.867 ± 0.014	1.971AsnIle: 1.971 ± 0.024	1.452AsnLys: 1.452 ± 0.021	3.236AsnLeu: 3.236 ± 0.027	0.794AsnMet: 0.794 ± 0.013	1.395AsnAsn: 1.395 ± 0.019	2.439AsnPro: 2.439 ± 0.023	1.341AsnGln: 1.341 ± 0.018	2.009AsnArg: 2.009 ± 0.02	2.654AsnSer: 2.654 ± 0.027	2.055AsnThr: 2.055 ± 0.024	2.3AsnVal: 2.3 ± 0.026	0.546AsnTrp: 0.546 ± 0.01	1.046AsnTyr: 1.046 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.244ProAla: 5.244 ± 0.045	0.59ProCys: 0.59 ± 0.012	3.206ProAsp: 3.206 ± 0.028	3.842ProGlu: 3.842 ± 0.037	2.109ProPhe: 2.109 ± 0.025	3.889ProGly: 3.889 ± 0.035	1.371ProHis: 1.371 ± 0.02	2.487ProIle: 2.487 ± 0.026	2.484ProLys: 2.484 ± 0.026	4.848ProLeu: 4.848 ± 0.036	1.016ProMet: 1.016 ± 0.019	2.119ProAsn: 2.119 ± 0.026	4.902ProPro: 4.902 ± 0.063	2.43ProGln: 2.43 ± 0.03	3.516ProArg: 3.516 ± 0.032	6.34ProSer: 6.34 ± 0.056	3.858ProThr: 3.858 ± 0.034	3.717ProVal: 3.717 ± 0.038	0.771ProTrp: 0.771 ± 0.012	1.54ProTyr: 1.54 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.471GlnAla: 3.471 ± 0.034	0.479GlnCys: 0.479 ± 0.01	1.968GlnAsp: 1.968 ± 0.021	2.455GlnGlu: 2.455 ± 0.024	1.322GlnPhe: 1.322 ± 0.019	2.423GlnGly: 2.423 ± 0.028	1.057GlnHis: 1.057 ± 0.018	1.937GlnIle: 1.937 ± 0.021	1.995GlnLys: 1.995 ± 0.026	3.582GlnLeu: 3.582 ± 0.029	0.903GlnMet: 0.903 ± 0.014	1.546GlnAsn: 1.546 ± 0.019	2.556GlnPro: 2.556 ± 0.031	2.329GlnGln: 2.329 ± 0.042	2.79GlnArg: 2.79 ± 0.026	3.36GlnSer: 3.36 ± 0.032	2.373GlnThr: 2.373 ± 0.023	2.24GlnVal: 2.24 ± 0.023	0.588GlnTrp: 0.588 ± 0.011	1.139GlnTyr: 1.139 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.866ArgAla: 4.866 ± 0.034	0.771ArgCys: 0.771 ± 0.016	3.379ArgAsp: 3.379 ± 0.033	4.022ArgGlu: 4.022 ± 0.043	2.279ArgPhe: 2.279 ± 0.023	3.688ArgGly: 3.688 ± 0.039	1.631ArgHis: 1.631 ± 0.022	3.038ArgIle: 3.038 ± 0.027	3.514ArgLys: 3.514 ± 0.032	5.877ArgLeu: 5.877 ± 0.041	1.365ArgMet: 1.365 ± 0.017	2.297ArgAsn: 2.297 ± 0.023	3.604ArgPro: 3.604 ± 0.037	2.768ArgGln: 2.768 ± 0.027	5.384ArgArg: 5.384 ± 0.049	5.117ArgSer: 5.117 ± 0.038	3.451ArgThr: 3.451 ± 0.027	3.564ArgVal: 3.564 ± 0.029	0.969ArgTrp: 0.969 ± 0.013	1.741ArgTyr: 1.741 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.929SerAla: 6.929 ± 0.051	0.948SerCys: 0.948 ± 0.015	4.252SerAsp: 4.252 ± 0.035	4.237SerGlu: 4.237 ± 0.036	3.082SerPhe: 3.082 ± 0.027	5.576SerGly: 5.576 ± 0.035	2.034SerHis: 2.034 ± 0.024	4.064SerIle: 4.064 ± 0.035	3.643SerLys: 3.643 ± 0.03	7.623SerLeu: 7.623 ± 0.048	1.698SerMet: 1.698 ± 0.021	2.983SerAsn: 2.983 ± 0.031	5.578SerPro: 5.578 ± 0.052	3.493SerGln: 3.493 ± 0.032	5.316SerArg: 5.316 ± 0.039	9.086SerSer: 9.086 ± 0.08	5.636SerThr: 5.636 ± 0.048	4.845SerVal: 4.845 ± 0.032	1.127SerTrp: 1.127 ± 0.017	2.078SerTyr: 2.078 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.257ThrAla: 5.257 ± 0.038	0.768ThrCys: 0.768 ± 0.013	2.886ThrAsp: 2.886 ± 0.026	3.129ThrGlu: 3.129 ± 0.029	2.2ThrPhe: 2.2 ± 0.023	4.196ThrGly: 4.196 ± 0.036	1.276ThrHis: 1.276 ± 0.016	3.042ThrIle: 3.042 ± 0.028	2.455ThrLys: 2.455 ± 0.022	5.241ThrLeu: 5.241 ± 0.038	1.189ThrMet: 1.189 ± 0.015	2.025ThrAsn: 2.025 ± 0.025	4.195ThrPro: 4.195 ± 0.038	2.065ThrGln: 2.065 ± 0.02	3.124ThrArg: 3.124 ± 0.027	5.294ThrSer: 5.294 ± 0.042	4.114ThrThr: 4.114 ± 0.056	3.96ThrVal: 3.96 ± 0.03	0.842ThrTrp: 0.842 ± 0.015	1.606ThrTyr: 1.606 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.296ValAla: 5.296 ± 0.038	0.895ValCys: 0.895 ± 0.015	3.727ValAsp: 3.727 ± 0.03	3.855ValGlu: 3.855 ± 0.032	2.496ValPhe: 2.496 ± 0.024	3.979ValGly: 3.979 ± 0.032	1.442ValHis: 1.442 ± 0.017	3.068ValIle: 3.068 ± 0.028	2.787ValLys: 2.787 ± 0.026	5.74ValLeu: 5.74 ± 0.04	1.32ValMet: 1.32 ± 0.016	2.231ValAsn: 2.231 ± 0.021	3.663ValPro: 3.663 ± 0.031	2.451ValGln: 2.451 ± 0.021	3.636ValArg: 3.636 ± 0.029	4.929ValSer: 4.929 ± 0.034	3.622ValThr: 3.622 ± 0.037	4.257ValVal: 4.257 ± 0.036	0.863ValTrp: 0.863 ± 0.014	1.796ValTyr: 1.796 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.115TrpAla: 1.115 ± 0.016	0.187TrpCys: 0.187 ± 0.006	0.881TrpAsp: 0.881 ± 0.016	0.822TrpGlu: 0.822 ± 0.013	0.537TrpPhe: 0.537 ± 0.012	0.916TrpGly: 0.916 ± 0.016	0.35TrpHis: 0.35 ± 0.009	0.758TrpIle: 0.758 ± 0.012	0.791TrpLys: 0.791 ± 0.014	1.38TrpLeu: 1.38 ± 0.018	0.373TrpMet: 0.373 ± 0.008	0.621TrpAsn: 0.621 ± 0.012	0.593TrpPro: 0.593 ± 0.011	0.569TrpGln: 0.569 ± 0.012	0.996TrpArg: 0.996 ± 0.017	1.057TrpSer: 1.057 ± 0.015	0.945TrpThr: 0.945 ± 0.015	0.881TrpVal: 0.881 ± 0.014	0.272TrpTrp: 0.272 ± 0.009	0.433TrpTyr: 0.433 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.21TyrAla: 2.21 ± 0.021	0.427TyrCys: 0.427 ± 0.011	1.591TyrAsp: 1.591 ± 0.019	1.561TyrGlu: 1.561 ± 0.018	1.195TyrPhe: 1.195 ± 0.017	2.056TyrGly: 2.056 ± 0.025	0.762TyrHis: 0.762 ± 0.013	1.467TyrIle: 1.467 ± 0.017	1.077TyrLys: 1.077 ± 0.016	2.773TyrLeu: 2.773 ± 0.028	0.609TyrMet: 0.609 ± 0.013	1.098TyrAsn: 1.098 ± 0.016	1.559TyrPro: 1.559 ± 0.021	1.107TyrGln: 1.107 ± 0.014	1.712TyrArg: 1.712 ± 0.021	2.085TyrSer: 2.085 ± 0.019	1.613TyrThr: 1.613 ± 0.021	1.701TyrVal: 1.701 ± 0.021	0.441TyrTrp: 0.441 ± 0.008	0.961TyrTyr: 0.961 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9647 proteins (4742919 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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