Amino acid dipepetide frequency for Fibularhizoctonia sp. CBS 109695

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.079AlaAla: 10.079 ± 0.051	1.429AlaCys: 1.429 ± 0.012	4.543AlaAsp: 4.543 ± 0.024	4.995AlaGlu: 4.995 ± 0.027	3.498AlaPhe: 3.498 ± 0.02	6.362AlaGly: 6.362 ± 0.035	2.491AlaHis: 2.491 ± 0.016	4.573AlaIle: 4.573 ± 0.024	3.84AlaLys: 3.84 ± 0.022	9.261AlaLeu: 9.261 ± 0.033	2.102AlaMet: 2.102 ± 0.015	2.924AlaAsn: 2.924 ± 0.017	5.685AlaPro: 5.685 ± 0.035	3.699AlaGln: 3.699 ± 0.022	5.885AlaArg: 5.885 ± 0.029	7.81AlaSer: 7.81 ± 0.035	5.497AlaThr: 5.497 ± 0.026	6.018AlaVal: 6.018 ± 0.027	1.346AlaTrp: 1.346 ± 0.012	2.411AlaTyr: 2.411 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.375CysAla: 1.375 ± 0.012	0.317CysCys: 0.317 ± 0.006	0.759CysAsp: 0.759 ± 0.009	0.652CysGlu: 0.652 ± 0.009	0.584CysPhe: 0.584 ± 0.008	1.128CysGly: 1.128 ± 0.01	0.44CysHis: 0.44 ± 0.007	0.845CysIle: 0.845 ± 0.01	0.571CysLys: 0.571 ± 0.008	1.454CysLeu: 1.454 ± 0.013	0.374CysMet: 0.374 ± 0.006	0.503CysAsn: 0.503 ± 0.008	0.917CysPro: 0.917 ± 0.012	0.533CysGln: 0.533 ± 0.008	0.969CysArg: 0.969 ± 0.009	1.236CysSer: 1.236 ± 0.014	1.0CysThr: 1.0 ± 0.012	0.937CysVal: 0.937 ± 0.011	0.246CysTrp: 0.246 ± 0.004	0.384CysTyr: 0.384 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	5.071AspAla: 5.071 ± 0.021	0.685AspCys: 0.685 ± 0.009	3.698AspAsp: 3.698 ± 0.023	3.782AspGlu: 3.782 ± 0.023	1.95AspPhe: 1.95 ± 0.015	4.098AspGly: 4.098 ± 0.027	1.346AspHis: 1.346 ± 0.012	3.104AspIle: 3.104 ± 0.018	2.003AspLys: 2.003 ± 0.015	4.805AspLeu: 4.805 ± 0.026	1.237AspMet: 1.237 ± 0.011	1.611AspAsn: 1.611 ± 0.014	3.091AspPro: 3.091 ± 0.017	1.562AspGln: 1.562 ± 0.013	2.797AspArg: 2.797 ± 0.018	3.823AspSer: 3.823 ± 0.021	3.0AspThr: 3.0 ± 0.017	3.722AspVal: 3.722 ± 0.02	0.918AspTrp: 0.918 ± 0.009	1.324AspTyr: 1.324 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.091GluAla: 5.091 ± 0.031	0.78GluCys: 0.78 ± 0.01	3.71GluAsp: 3.71 ± 0.023	4.471GluGlu: 4.471 ± 0.032	1.652GluPhe: 1.652 ± 0.013	3.677GluGly: 3.677 ± 0.022	1.553GluHis: 1.553 ± 0.014	2.713GluIle: 2.713 ± 0.019	2.704GluLys: 2.704 ± 0.018	4.892GluLeu: 4.892 ± 0.026	1.342GluMet: 1.342 ± 0.013	1.74GluAsn: 1.74 ± 0.015	2.443GluPro: 2.443 ± 0.018	2.047GluGln: 2.047 ± 0.018	3.745GluArg: 3.745 ± 0.028	3.636GluSer: 3.636 ± 0.019	2.805GluThr: 2.805 ± 0.016	3.334GluVal: 3.334 ± 0.02	0.932GluTrp: 0.932 ± 0.01	1.401GluTyr: 1.401 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	3.275PheAla: 3.275 ± 0.018	0.59PheCys: 0.59 ± 0.007	2.075PheAsp: 2.075 ± 0.016	2.007PheGlu: 2.007 ± 0.015	1.56PhePhe: 1.56 ± 0.014	2.603PheGly: 2.603 ± 0.02	0.928PheHis: 0.928 ± 0.01	1.824PheIle: 1.824 ± 0.015	1.475PheLys: 1.475 ± 0.012	3.49PheLeu: 3.49 ± 0.02	0.754PheMet: 0.754 ± 0.009	1.356PheAsn: 1.356 ± 0.012	1.978PhePro: 1.978 ± 0.014	1.239PheGln: 1.239 ± 0.01	1.946PheArg: 1.946 ± 0.014	3.015PheSer: 3.015 ± 0.018	2.153PheThr: 2.153 ± 0.013	2.381PheVal: 2.381 ± 0.017	0.626PheTrp: 0.626 ± 0.008	0.958PheTyr: 0.958 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	5.908GlyAla: 5.908 ± 0.032	1.101GlyCys: 1.101 ± 0.012	3.549GlyAsp: 3.549 ± 0.02	3.486GlyGlu: 3.486 ± 0.021	2.45GlyPhe: 2.45 ± 0.016	5.659GlyGly: 5.659 ± 0.039	1.883GlyHis: 1.883 ± 0.016	3.207GlyIle: 3.207 ± 0.018	3.261GlyLys: 3.261 ± 0.02	5.923GlyLeu: 5.923 ± 0.024	1.598GlyMet: 1.598 ± 0.014	2.29GlyAsn: 2.29 ± 0.018	3.468GlyPro: 3.468 ± 0.022	2.387GlyGln: 2.387 ± 0.017	4.315GlyArg: 4.315 ± 0.026	5.591GlySer: 5.591 ± 0.03	4.079GlyThr: 4.079 ± 0.023	4.386GlyVal: 4.386 ± 0.025	1.19GlyTrp: 1.19 ± 0.012	1.8GlyTyr: 1.8 ± 0.014	0.0GlyXaa: 0.0 ± 0.0
His	2.45HisAla: 2.45 ± 0.018	0.486HisCys: 0.486 ± 0.007	1.319HisAsp: 1.319 ± 0.012	1.3HisGlu: 1.3 ± 0.013	1.057HisPhe: 1.057 ± 0.012	1.753HisGly: 1.753 ± 0.014	0.956HisHis: 0.956 ± 0.01	1.554HisIle: 1.554 ± 0.014	0.929HisLys: 0.929 ± 0.01	2.773HisLeu: 2.773 ± 0.018	0.586HisMet: 0.586 ± 0.007	0.889HisAsn: 0.889 ± 0.009	2.204HisPro: 2.204 ± 0.016	0.96HisGln: 0.96 ± 0.011	1.841HisArg: 1.841 ± 0.014	2.172HisSer: 2.172 ± 0.015	1.704HisThr: 1.704 ± 0.015	1.665HisVal: 1.665 ± 0.013	0.407HisTrp: 0.407 ± 0.006	0.709HisTyr: 0.709 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.615IleAla: 4.615 ± 0.024	0.873IleCys: 0.873 ± 0.009	2.673IleAsp: 2.673 ± 0.017	2.518IleGlu: 2.518 ± 0.016	2.007IlePhe: 2.007 ± 0.016	3.08IleGly: 3.08 ± 0.018	1.356IleHis: 1.356 ± 0.013	2.673IleIle: 2.673 ± 0.019	1.939IleLys: 1.939 ± 0.015	4.667IleLeu: 4.667 ± 0.024	1.075IleMet: 1.075 ± 0.01	1.671IleAsn: 1.671 ± 0.013	3.121IlePro: 3.121 ± 0.018	1.8IleGln: 1.8 ± 0.014	2.847IleArg: 2.847 ± 0.02	4.116IleSer: 4.116 ± 0.022	3.067IleThr: 3.067 ± 0.019	3.32IleVal: 3.32 ± 0.019	0.831IleTrp: 0.831 ± 0.012	1.341IleTyr: 1.341 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.012LysAla: 4.012 ± 0.024	0.582LysCys: 0.582 ± 0.009	2.234LysAsp: 2.234 ± 0.018	2.586LysGlu: 2.586 ± 0.021	1.284LysPhe: 1.284 ± 0.012	2.745LysGly: 2.745 ± 0.018	1.157LysHis: 1.157 ± 0.01	2.039LysIle: 2.039 ± 0.015	2.502LysLys: 2.502 ± 0.024	3.769LysLeu: 3.769 ± 0.021	0.905LysMet: 0.905 ± 0.009	1.32LysAsn: 1.32 ± 0.01	2.218LysPro: 2.218 ± 0.017	1.525LysGln: 1.525 ± 0.014	2.958LysArg: 2.958 ± 0.021	3.073LysSer: 3.073 ± 0.02	2.416LysThr: 2.416 ± 0.017	2.457LysVal: 2.457 ± 0.017	0.646LysTrp: 0.646 ± 0.007	1.215LysTyr: 1.215 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	9.222LeuAla: 9.222 ± 0.037	1.487LeuCys: 1.487 ± 0.013	5.006LeuAsp: 5.006 ± 0.023	5.088LeuGlu: 5.088 ± 0.027	3.343LeuPhe: 3.343 ± 0.019	6.029LeuGly: 6.029 ± 0.027	2.72LeuHis: 2.72 ± 0.018	3.959LeuIle: 3.959 ± 0.017	3.826LeuLys: 3.826 ± 0.023	8.825LeuLeu: 8.825 ± 0.036	1.835LeuMet: 1.835 ± 0.013	2.959LeuAsn: 2.959 ± 0.018	6.192LeuPro: 6.192 ± 0.026	3.743LeuGln: 3.743 ± 0.022	5.994LeuArg: 5.994 ± 0.029	7.856LeuSer: 7.856 ± 0.033	5.239LeuThr: 5.239 ± 0.025	5.81LeuVal: 5.81 ± 0.028	1.331LeuTrp: 1.331 ± 0.013	2.52LeuTyr: 2.52 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	2.075MetAla: 2.075 ± 0.015	0.342MetCys: 0.342 ± 0.005	1.239MetAsp: 1.239 ± 0.011	1.165MetGlu: 1.165 ± 0.01	0.767MetPhe: 0.767 ± 0.009	1.448MetGly: 1.448 ± 0.012	0.666MetHis: 0.666 ± 0.009	0.957MetIle: 0.957 ± 0.012	0.923MetLys: 0.923 ± 0.01	1.993MetLeu: 1.993 ± 0.013	0.538MetMet: 0.538 ± 0.008	0.703MetAsn: 0.703 ± 0.008	1.379MetPro: 1.379 ± 0.011	0.924MetGln: 0.924 ± 0.01	1.37MetArg: 1.37 ± 0.012	2.01MetSer: 2.01 ± 0.015	1.28MetThr: 1.28 ± 0.011	1.302MetVal: 1.302 ± 0.011	0.318MetTrp: 0.318 ± 0.006	0.59MetTyr: 0.59 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.103AsnAla: 3.103 ± 0.02	0.463AsnCys: 0.463 ± 0.006	1.612AsnAsp: 1.612 ± 0.014	1.564AsnGlu: 1.564 ± 0.013	1.224AsnPhe: 1.224 ± 0.012	2.485AsnGly: 2.485 ± 0.019	0.872AsnHis: 0.872 ± 0.01	2.084AsnIle: 2.084 ± 0.013	1.168AsnLys: 1.168 ± 0.01	3.118AsnLeu: 3.118 ± 0.02	0.787AsnMet: 0.787 ± 0.009	1.229AsnAsn: 1.229 ± 0.013	2.145AsnPro: 2.145 ± 0.016	1.077AsnGln: 1.077 ± 0.012	1.651AsnArg: 1.651 ± 0.014	2.524AsnSer: 2.524 ± 0.016	2.208AsnThr: 2.208 ± 0.015	2.216AsnVal: 2.216 ± 0.018	0.476AsnTrp: 0.476 ± 0.007	0.889AsnTyr: 0.889 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	6.125ProAla: 6.125 ± 0.034	0.708ProCys: 0.708 ± 0.007	3.127ProAsp: 3.127 ± 0.019	3.306ProGlu: 3.306 ± 0.017	2.15ProPhe: 2.15 ± 0.017	3.819ProGly: 3.819 ± 0.022	1.719ProHis: 1.719 ± 0.015	2.79ProIle: 2.79 ± 0.016	2.263ProLys: 2.263 ± 0.016	5.363ProLeu: 5.363 ± 0.025	1.164ProMet: 1.164 ± 0.011	2.07ProAsn: 2.07 ± 0.016	5.774ProPro: 5.774 ± 0.052	2.249ProGln: 2.249 ± 0.021	3.66ProArg: 3.66 ± 0.023	6.536ProSer: 6.536 ± 0.034	4.287ProThr: 4.287 ± 0.024	3.643ProVal: 3.643 ± 0.024	0.76ProTrp: 0.76 ± 0.009	1.466ProTyr: 1.466 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	3.424GlnAla: 3.424 ± 0.02	0.616GlnCys: 0.616 ± 0.009	1.832GlnAsp: 1.832 ± 0.015	2.055GlnGlu: 2.055 ± 0.019	1.229GlnPhe: 1.229 ± 0.012	2.304GlnGly: 2.304 ± 0.017	1.153GlnHis: 1.153 ± 0.01	1.748GlnIle: 1.748 ± 0.013	1.508GlnLys: 1.508 ± 0.013	3.509GlnLeu: 3.509 ± 0.021	0.883GlnMet: 0.883 ± 0.01	1.22GlnAsn: 1.22 ± 0.012	2.286GlnPro: 2.286 ± 0.019	1.888GlnGln: 1.888 ± 0.03	2.447GlnArg: 2.447 ± 0.017	2.88GlnSer: 2.88 ± 0.018	2.172GlnThr: 2.172 ± 0.016	2.088GlnVal: 2.088 ± 0.017	0.626GlnTrp: 0.626 ± 0.008	1.036GlnTyr: 1.036 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	5.872ArgAla: 5.872 ± 0.026	0.992ArgCys: 0.992 ± 0.009	3.159ArgAsp: 3.159 ± 0.02	3.556ArgGlu: 3.556 ± 0.024	2.013ArgPhe: 2.013 ± 0.014	3.908ArgGly: 3.908 ± 0.022	1.745ArgHis: 1.745 ± 0.016	3.038ArgIle: 3.038 ± 0.018	2.927ArgLys: 2.927 ± 0.019	5.658ArgLeu: 5.658 ± 0.026	1.435ArgMet: 1.435 ± 0.012	1.942ArgAsn: 1.942 ± 0.012	3.661ArgPro: 3.661 ± 0.023	2.337ArgGln: 2.337 ± 0.018	5.102ArgArg: 5.102 ± 0.034	4.841ArgSer: 4.841 ± 0.028	3.617ArgThr: 3.617 ± 0.022	3.874ArgVal: 3.874 ± 0.019	1.072ArgTrp: 1.072 ± 0.01	1.572ArgTyr: 1.572 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	7.583SerAla: 7.583 ± 0.029	1.165SerCys: 1.165 ± 0.012	4.125SerAsp: 4.125 ± 0.022	3.802SerGlu: 3.802 ± 0.022	3.035SerPhe: 3.035 ± 0.018	5.557SerGly: 5.557 ± 0.026	2.146SerHis: 2.146 ± 0.014	4.069SerIle: 4.069 ± 0.021	3.211SerLys: 3.211 ± 0.019	7.595SerLeu: 7.595 ± 0.028	1.728SerMet: 1.728 ± 0.013	2.75SerAsn: 2.75 ± 0.018	5.918SerPro: 5.918 ± 0.033	2.977SerGln: 2.977 ± 0.021	5.072SerArg: 5.072 ± 0.028	8.867SerSer: 8.867 ± 0.047	5.87SerThr: 5.87 ± 0.027	4.89SerVal: 4.89 ± 0.024	1.174SerTrp: 1.174 ± 0.011	1.991SerTyr: 1.991 ± 0.014	0.0SerXaa: 0.0 ± 0.0
Thr	5.631ThrAla: 5.631 ± 0.03	0.942ThrCys: 0.942 ± 0.009	2.803ThrAsp: 2.803 ± 0.018	2.666ThrGlu: 2.666 ± 0.018	2.325ThrPhe: 2.325 ± 0.015	4.138ThrGly: 4.138 ± 0.023	1.644ThrHis: 1.644 ± 0.012	3.154ThrIle: 3.154 ± 0.022	2.216ThrLys: 2.216 ± 0.014	5.882ThrLeu: 5.882 ± 0.028	1.269ThrMet: 1.269 ± 0.012	1.969ThrAsn: 1.969 ± 0.014	4.388ThrPro: 4.388 ± 0.023	2.039ThrGln: 2.039 ± 0.015	3.529ThrArg: 3.529 ± 0.019	5.712ThrSer: 5.712 ± 0.028	4.186ThrThr: 4.186 ± 0.026	3.946ThrVal: 3.946 ± 0.024	0.89ThrTrp: 0.89 ± 0.009	1.564ThrTyr: 1.564 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	5.886ValAla: 5.886 ± 0.03	0.976ValCys: 0.976 ± 0.01	3.672ValAsp: 3.672 ± 0.022	3.534ValGlu: 3.534 ± 0.02	2.478ValPhe: 2.478 ± 0.02	3.939ValGly: 3.939 ± 0.023	1.776ValHis: 1.776 ± 0.013	3.097ValIle: 3.097 ± 0.018	2.661ValLys: 2.661 ± 0.016	6.074ValLeu: 6.074 ± 0.028	1.359ValMet: 1.359 ± 0.012	2.113ValAsn: 2.113 ± 0.016	3.837ValPro: 3.837 ± 0.021	2.376ValGln: 2.376 ± 0.015	3.58ValArg: 3.58 ± 0.021	4.678ValSer: 4.678 ± 0.024	3.631ValThr: 3.631 ± 0.019	4.469ValVal: 4.469 ± 0.022	1.029ValTrp: 1.029 ± 0.01	1.845ValTyr: 1.845 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.331TrpAla: 1.331 ± 0.011	0.239TrpCys: 0.239 ± 0.005	0.989TrpAsp: 0.989 ± 0.013	0.831TrpGlu: 0.831 ± 0.009	0.551TrpPhe: 0.551 ± 0.007	0.979TrpGly: 0.979 ± 0.011	0.408TrpHis: 0.408 ± 0.007	0.779TrpIle: 0.779 ± 0.01	0.748TrpLys: 0.748 ± 0.009	1.456TrpLeu: 1.456 ± 0.012	0.424TrpMet: 0.424 ± 0.007	0.61TrpAsn: 0.61 ± 0.009	0.743TrpPro: 0.743 ± 0.009	0.549TrpGln: 0.549 ± 0.007	1.076TrpArg: 1.076 ± 0.012	1.17TrpSer: 1.17 ± 0.011	0.962TrpThr: 0.962 ± 0.01	0.982TrpVal: 0.982 ± 0.009	0.309TrpTrp: 0.309 ± 0.006	0.403TrpTyr: 0.403 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.323TyrAla: 2.323 ± 0.017	0.452TyrCys: 0.452 ± 0.007	1.499TyrAsp: 1.499 ± 0.013	1.307TyrGlu: 1.307 ± 0.011	1.074TyrPhe: 1.074 ± 0.012	1.821TyrGly: 1.821 ± 0.014	0.757TyrHis: 0.757 ± 0.01	1.382TyrIle: 1.382 ± 0.013	0.968TyrLys: 0.968 ± 0.009	2.475TyrLeu: 2.475 ± 0.016	0.594TyrMet: 0.594 ± 0.009	1.028TyrAsn: 1.028 ± 0.01	1.53TyrPro: 1.53 ± 0.014	0.994TyrGln: 0.994 ± 0.011	1.538TyrArg: 1.538 ± 0.013	1.975TyrSer: 1.975 ± 0.016	1.722TyrThr: 1.722 ± 0.015	1.569TyrVal: 1.569 ± 0.012	0.411TyrTrp: 0.411 ± 0.006	0.858TyrTyr: 0.858 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 31941 proteins (10750530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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