Amino acid dipepetide frequency for Hortaea thailandica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.649AlaAla: 10.649 ± 0.078	1.053AlaCys: 1.053 ± 0.021	4.732AlaAsp: 4.732 ± 0.04	6.106AlaGlu: 6.106 ± 0.049	3.261AlaPhe: 3.261 ± 0.028	7.042AlaGly: 7.042 ± 0.05	1.97AlaHis: 1.97 ± 0.021	3.862AlaIle: 3.862 ± 0.034	4.443AlaLys: 4.443 ± 0.043	8.148AlaLeu: 8.148 ± 0.047	2.169AlaMet: 2.169 ± 0.022	3.145AlaAsn: 3.145 ± 0.027	5.537AlaPro: 5.537 ± 0.051	4.062AlaGln: 4.062 ± 0.037	5.557AlaArg: 5.557 ± 0.036	7.97AlaSer: 7.97 ± 0.058	5.835AlaThr: 5.835 ± 0.039	5.835AlaVal: 5.835 ± 0.038	1.19AlaTrp: 1.19 ± 0.019	2.342AlaTyr: 2.342 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.911CysAla: 0.911 ± 0.015	0.202CysCys: 0.202 ± 0.008	0.582CysAsp: 0.582 ± 0.013	0.597CysGlu: 0.597 ± 0.013	0.48CysPhe: 0.48 ± 0.011	0.87CysGly: 0.87 ± 0.017	0.272CysHis: 0.272 ± 0.008	0.564CysIle: 0.564 ± 0.013	0.447CysLys: 0.447 ± 0.011	1.121CysLeu: 1.121 ± 0.021	0.245CysMet: 0.245 ± 0.008	0.379CysAsn: 0.379 ± 0.01	0.582CysPro: 0.582 ± 0.015	0.394CysGln: 0.394 ± 0.009	0.66CysArg: 0.66 ± 0.014	0.764CysSer: 0.764 ± 0.016	0.629CysThr: 0.629 ± 0.013	0.741CysVal: 0.741 ± 0.013	0.184CysTrp: 0.184 ± 0.006	0.329CysTyr: 0.329 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.302AspAla: 5.302 ± 0.034	0.603AspCys: 0.603 ± 0.012	4.493AspAsp: 4.493 ± 0.042	4.833AspGlu: 4.833 ± 0.048	2.266AspPhe: 2.266 ± 0.023	4.487AspGly: 4.487 ± 0.034	1.203AspHis: 1.203 ± 0.016	2.542AspIle: 2.542 ± 0.025	2.136AspLys: 2.136 ± 0.023	4.956AspLeu: 4.956 ± 0.034	1.318AspMet: 1.318 ± 0.019	1.688AspAsn: 1.688 ± 0.021	3.221AspPro: 3.221 ± 0.031	1.993AspGln: 1.993 ± 0.025	3.181AspArg: 3.181 ± 0.034	3.956AspSer: 3.956 ± 0.037	2.946AspThr: 2.946 ± 0.028	3.901AspVal: 3.901 ± 0.031	0.893AspTrp: 0.893 ± 0.017	1.607AspTyr: 1.607 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	6.169GluAla: 6.169 ± 0.047	0.558GluCys: 0.558 ± 0.012	4.579GluAsp: 4.579 ± 0.045	5.91GluGlu: 5.91 ± 0.072	1.632GluPhe: 1.632 ± 0.02	4.748GluGly: 4.748 ± 0.043	1.506GluHis: 1.506 ± 0.021	2.538GluIle: 2.538 ± 0.026	3.636GluLys: 3.636 ± 0.045	5.153GluLeu: 5.153 ± 0.047	1.564GluMet: 1.564 ± 0.02	1.916GluAsn: 1.916 ± 0.021	2.872GluPro: 2.872 ± 0.029	3.023GluGln: 3.023 ± 0.031	4.606GluArg: 4.606 ± 0.046	4.034GluSer: 4.034 ± 0.038	3.496GluThr: 3.496 ± 0.029	3.94GluVal: 3.94 ± 0.033	0.835GluTrp: 0.835 ± 0.015	1.577GluTyr: 1.577 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.221PheAla: 3.221 ± 0.03	0.499PheCys: 0.499 ± 0.012	2.135PheAsp: 2.135 ± 0.02	2.084PheGlu: 2.084 ± 0.025	1.387PhePhe: 1.387 ± 0.02	2.863PheGly: 2.863 ± 0.031	0.81PheHis: 0.81 ± 0.014	1.44PheIle: 1.44 ± 0.024	1.314PheLys: 1.314 ± 0.018	3.022PheLeu: 3.022 ± 0.034	0.719PheMet: 0.719 ± 0.013	1.274PheAsn: 1.274 ± 0.019	1.703PhePro: 1.703 ± 0.022	1.26PheGln: 1.26 ± 0.017	1.806PheArg: 1.806 ± 0.021	2.564PheSer: 2.564 ± 0.029	2.093PheThr: 2.093 ± 0.017	2.209PheVal: 2.209 ± 0.024	0.585PheTrp: 0.585 ± 0.012	1.006PheTyr: 1.006 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	6.183GlyAla: 6.183 ± 0.044	0.824GlyCys: 0.824 ± 0.015	3.902GlyAsp: 3.902 ± 0.033	4.415GlyGlu: 4.415 ± 0.04	2.775GlyPhe: 2.775 ± 0.03	7.49GlyGly: 7.49 ± 0.088	1.744GlyHis: 1.744 ± 0.024	3.139GlyIle: 3.139 ± 0.027	3.757GlyLys: 3.757 ± 0.036	6.289GlyLeu: 6.289 ± 0.04	1.965GlyMet: 1.965 ± 0.023	2.532GlyAsn: 2.532 ± 0.03	3.383GlyPro: 3.383 ± 0.032	2.939GlyGln: 2.939 ± 0.029	4.677GlyArg: 4.677 ± 0.043	6.14GlySer: 6.14 ± 0.062	4.129GlyThr: 4.129 ± 0.03	4.767GlyVal: 4.767 ± 0.037	1.231GlyTrp: 1.231 ± 0.018	2.136GlyTyr: 2.136 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.188HisAla: 2.188 ± 0.024	0.304HisCys: 0.304 ± 0.008	1.368HisAsp: 1.368 ± 0.019	1.422HisGlu: 1.422 ± 0.019	0.912HisPhe: 0.912 ± 0.015	1.797HisGly: 1.797 ± 0.022	0.888HisHis: 0.888 ± 0.017	1.007HisIle: 1.007 ± 0.016	0.875HisLys: 0.875 ± 0.018	2.231HisLeu: 2.231 ± 0.023	0.463HisMet: 0.463 ± 0.009	0.813HisAsn: 0.813 ± 0.014	1.688HisPro: 1.688 ± 0.018	1.049HisGln: 1.049 ± 0.017	1.5HisArg: 1.5 ± 0.02	1.745HisSer: 1.745 ± 0.021	1.3HisThr: 1.3 ± 0.018	1.464HisVal: 1.464 ± 0.018	0.344HisTrp: 0.344 ± 0.009	0.672HisTyr: 0.672 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.927IleAla: 3.927 ± 0.03	0.6IleCys: 0.6 ± 0.012	2.577IleAsp: 2.577 ± 0.023	2.538IleGlu: 2.538 ± 0.025	1.591IlePhe: 1.591 ± 0.02	2.886IleGly: 2.886 ± 0.03	0.982IleHis: 0.982 ± 0.016	1.857IleIle: 1.857 ± 0.025	1.794IleLys: 1.794 ± 0.021	3.612IleLeu: 3.612 ± 0.035	0.899IleMet: 0.899 ± 0.014	1.481IleAsn: 1.481 ± 0.019	2.457IlePro: 2.457 ± 0.024	1.543IleGln: 1.543 ± 0.018	2.37IleArg: 2.37 ± 0.026	3.061IleSer: 3.061 ± 0.03	2.502IleThr: 2.502 ± 0.027	2.665IleVal: 2.665 ± 0.024	0.589IleTrp: 0.589 ± 0.012	1.172IleTyr: 1.172 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.571LysAla: 4.571 ± 0.038	0.419LysCys: 0.419 ± 0.01	2.681LysAsp: 2.681 ± 0.031	3.258LysGlu: 3.258 ± 0.038	1.183LysPhe: 1.183 ± 0.019	3.234LysGly: 3.234 ± 0.032	1.174LysHis: 1.174 ± 0.018	1.801LysIle: 1.801 ± 0.025	3.238LysLys: 3.238 ± 0.048	3.794LysLeu: 3.794 ± 0.038	1.031LysMet: 1.031 ± 0.017	1.425LysAsn: 1.425 ± 0.019	2.803LysPro: 2.803 ± 0.036	2.099LysGln: 2.099 ± 0.025	3.731LysArg: 3.731 ± 0.034	3.151LysSer: 3.151 ± 0.031	2.733LysThr: 2.733 ± 0.029	2.739LysVal: 2.739 ± 0.032	0.608LysTrp: 0.608 ± 0.012	1.195LysTyr: 1.195 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.234LeuAla: 8.234 ± 0.049	1.078LeuCys: 1.078 ± 0.017	5.013LeuAsp: 5.013 ± 0.041	5.374LeuGlu: 5.374 ± 0.043	2.952LeuPhe: 2.952 ± 0.028	5.848LeuGly: 5.848 ± 0.038	2.211LeuHis: 2.211 ± 0.021	3.283LeuIle: 3.283 ± 0.029	3.933LeuLys: 3.933 ± 0.033	7.966LeuLeu: 7.966 ± 0.056	1.705LeuMet: 1.705 ± 0.021	2.856LeuAsn: 2.856 ± 0.032	5.658LeuPro: 5.658 ± 0.045	3.979LeuGln: 3.979 ± 0.037	5.737LeuArg: 5.737 ± 0.042	6.661LeuSer: 6.661 ± 0.043	4.829LeuThr: 4.829 ± 0.031	4.964LeuVal: 4.964 ± 0.034	1.098LeuTrp: 1.098 ± 0.017	2.204LeuTyr: 2.204 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.351MetAla: 2.351 ± 0.023	0.23MetCys: 0.23 ± 0.008	1.275MetAsp: 1.275 ± 0.019	1.33MetGlu: 1.33 ± 0.018	0.693MetPhe: 0.693 ± 0.012	1.57MetGly: 1.57 ± 0.022	0.519MetHis: 0.519 ± 0.011	0.846MetIle: 0.846 ± 0.016	1.001MetLys: 1.001 ± 0.015	1.967MetLeu: 1.967 ± 0.022	0.597MetMet: 0.597 ± 0.012	0.795MetAsn: 0.795 ± 0.016	1.508MetPro: 1.508 ± 0.02	1.071MetGln: 1.071 ± 0.017	1.367MetArg: 1.367 ± 0.02	1.863MetSer: 1.863 ± 0.02	1.266MetThr: 1.266 ± 0.016	1.249MetVal: 1.249 ± 0.019	0.245MetTrp: 0.245 ± 0.008	0.515MetTyr: 0.515 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.287AsnAla: 3.287 ± 0.029	0.349AsnCys: 0.349 ± 0.01	1.928AsnAsp: 1.928 ± 0.025	1.942AsnGlu: 1.942 ± 0.02	1.232AsnPhe: 1.232 ± 0.017	3.084AsnGly: 3.084 ± 0.037	0.777AsnHis: 0.777 ± 0.014	1.656AsnIle: 1.656 ± 0.022	1.358AsnLys: 1.358 ± 0.021	2.876AsnLeu: 2.876 ± 0.031	0.762AsnMet: 0.762 ± 0.014	1.348AsnAsn: 1.348 ± 0.023	2.246AsnPro: 2.246 ± 0.025	1.211AsnGln: 1.211 ± 0.021	1.733AsnArg: 1.733 ± 0.02	2.37AsnSer: 2.37 ± 0.026	2.156AsnThr: 2.156 ± 0.024	2.27AsnVal: 2.27 ± 0.025	0.469AsnTrp: 0.469 ± 0.011	0.962AsnTyr: 0.962 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	6.065ProAla: 6.065 ± 0.049	0.438ProCys: 0.438 ± 0.011	3.19ProAsp: 3.19 ± 0.029	3.781ProGlu: 3.781 ± 0.032	1.899ProPhe: 1.899 ± 0.02	4.004ProGly: 4.004 ± 0.035	1.415ProHis: 1.415 ± 0.019	2.192ProIle: 2.192 ± 0.024	2.668ProLys: 2.668 ± 0.03	4.622ProLeu: 4.622 ± 0.036	1.133ProMet: 1.133 ± 0.019	2.153ProAsn: 2.153 ± 0.024	5.891ProPro: 5.891 ± 0.085	2.908ProGln: 2.908 ± 0.037	3.423ProArg: 3.423 ± 0.032	6.19ProSer: 6.19 ± 0.052	4.34ProThr: 4.34 ± 0.05	3.391ProVal: 3.391 ± 0.033	0.686ProTrp: 0.686 ± 0.013	1.522ProTyr: 1.522 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.204GlnAla: 4.204 ± 0.03	0.415GlnCys: 0.415 ± 0.011	2.259GlnAsp: 2.259 ± 0.023	2.59GlnGlu: 2.59 ± 0.026	1.082GlnPhe: 1.082 ± 0.016	2.716GlnGly: 2.716 ± 0.027	1.364GlnHis: 1.364 ± 0.02	1.67GlnIle: 1.67 ± 0.021	2.064GlnLys: 2.064 ± 0.025	3.514GlnLeu: 3.514 ± 0.031	0.998GlnMet: 0.998 ± 0.016	1.486GlnAsn: 1.486 ± 0.019	3.054GlnPro: 3.054 ± 0.039	3.555GlnGln: 3.555 ± 0.057	3.074GlnArg: 3.074 ± 0.031	3.322GlnSer: 3.322 ± 0.039	2.661GlnThr: 2.661 ± 0.026	2.183GlnVal: 2.183 ± 0.021	0.584GlnTrp: 0.584 ± 0.013	1.23GlnTyr: 1.23 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.247ArgAla: 5.247 ± 0.041	0.645ArgCys: 0.645 ± 0.012	3.421ArgAsp: 3.421 ± 0.036	4.288ArgGlu: 4.288 ± 0.044	2.05ArgPhe: 2.05 ± 0.023	4.094ArgGly: 4.094 ± 0.038	1.636ArgHis: 1.636 ± 0.019	2.509ArgIle: 2.509 ± 0.024	3.709ArgLys: 3.709 ± 0.041	5.415ArgLeu: 5.415 ± 0.041	1.435ArgMet: 1.435 ± 0.019	2.145ArgAsn: 2.145 ± 0.02	3.726ArgPro: 3.726 ± 0.033	3.048ArgGln: 3.048 ± 0.024	5.54ArgArg: 5.54 ± 0.056	4.906ArgSer: 4.906 ± 0.047	3.464ArgThr: 3.464 ± 0.03	3.36ArgVal: 3.36 ± 0.029	0.902ArgTrp: 0.902 ± 0.013	1.608ArgTyr: 1.608 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.451SerAla: 7.451 ± 0.059	0.721SerCys: 0.721 ± 0.012	4.204SerAsp: 4.204 ± 0.038	4.234SerGlu: 4.234 ± 0.037	2.619SerPhe: 2.619 ± 0.027	6.022SerGly: 6.022 ± 0.046	1.772SerHis: 1.772 ± 0.023	3.295SerIle: 3.295 ± 0.029	3.486SerLys: 3.486 ± 0.034	6.525SerLeu: 6.525 ± 0.049	1.743SerMet: 1.743 ± 0.021	2.826SerAsn: 2.826 ± 0.028	5.469SerPro: 5.469 ± 0.055	3.281SerGln: 3.281 ± 0.031	4.842SerArg: 4.842 ± 0.045	8.395SerSer: 8.395 ± 0.096	5.665SerThr: 5.665 ± 0.055	4.35SerVal: 4.35 ± 0.036	0.983SerTrp: 0.983 ± 0.016	1.956SerTyr: 1.956 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.096ThrAla: 6.096 ± 0.041	0.681ThrCys: 0.681 ± 0.012	2.922ThrAsp: 2.922 ± 0.028	3.106ThrGlu: 3.106 ± 0.024	2.192ThrPhe: 2.192 ± 0.023	4.335ThrGly: 4.335 ± 0.039	1.337ThrHis: 1.337 ± 0.017	2.667ThrIle: 2.667 ± 0.028	2.449ThrLys: 2.449 ± 0.023	5.282ThrLeu: 5.282 ± 0.037	1.211ThrMet: 1.211 ± 0.015	2.09ThrAsn: 2.09 ± 0.025	4.598ThrPro: 4.598 ± 0.044	2.299ThrGln: 2.299 ± 0.025	3.146ThrArg: 3.146 ± 0.028	5.507ThrSer: 5.507 ± 0.047	4.66ThrThr: 4.66 ± 0.056	3.606ThrVal: 3.606 ± 0.036	0.783ThrTrp: 0.783 ± 0.013	1.621ThrTyr: 1.621 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.463ValAla: 5.463 ± 0.044	0.761ValCys: 0.761 ± 0.013	3.746ValAsp: 3.746 ± 0.03	4.099ValGlu: 4.099 ± 0.037	2.216ValPhe: 2.216 ± 0.023	4.327ValGly: 4.327 ± 0.037	1.348ValHis: 1.348 ± 0.019	2.43ValIle: 2.43 ± 0.027	2.895ValLys: 2.895 ± 0.028	5.315ValLeu: 5.315 ± 0.041	1.372ValMet: 1.372 ± 0.018	2.085ValAsn: 2.085 ± 0.024	3.507ValPro: 3.507 ± 0.032	2.543ValGln: 2.543 ± 0.028	3.65ValArg: 3.65 ± 0.029	4.354ValSer: 4.354 ± 0.036	3.365ValThr: 3.365 ± 0.03	4.214ValVal: 4.214 ± 0.036	0.855ValTrp: 0.855 ± 0.014	1.638ValTyr: 1.638 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.072TrpAla: 1.072 ± 0.018	0.183TrpCys: 0.183 ± 0.005	0.815TrpAsp: 0.815 ± 0.015	0.813TrpGlu: 0.813 ± 0.013	0.484TrpPhe: 0.484 ± 0.01	0.837TrpGly: 0.837 ± 0.017	0.377TrpHis: 0.377 ± 0.01	0.639TrpIle: 0.639 ± 0.014	0.674TrpLys: 0.674 ± 0.012	1.312TrpLeu: 1.312 ± 0.019	0.359TrpMet: 0.359 ± 0.009	0.532TrpAsn: 0.532 ± 0.011	0.604TrpPro: 0.604 ± 0.012	0.66TrpGln: 0.66 ± 0.012	1.023TrpArg: 1.023 ± 0.015	1.005TrpSer: 1.005 ± 0.016	0.887TrpThr: 0.887 ± 0.017	0.777TrpVal: 0.777 ± 0.014	0.251TrpTrp: 0.251 ± 0.008	0.412TrpTyr: 0.412 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.314TyrAla: 2.314 ± 0.024	0.39TyrCys: 0.39 ± 0.01	1.701TyrAsp: 1.701 ± 0.021	1.573TyrGlu: 1.573 ± 0.02	1.085TyrPhe: 1.085 ± 0.017	2.164TyrGly: 2.164 ± 0.031	0.722TyrHis: 0.722 ± 0.014	1.168TyrIle: 1.168 ± 0.018	0.993TyrLys: 0.993 ± 0.018	2.465TyrLeu: 2.465 ± 0.023	0.573TyrMet: 0.573 ± 0.011	1.046TyrAsn: 1.046 ± 0.015	1.405TyrPro: 1.405 ± 0.02	1.105TyrGln: 1.105 ± 0.017	1.524TyrArg: 1.524 ± 0.02	1.88TyrSer: 1.88 ± 0.021	1.634TyrThr: 1.634 ± 0.022	1.558TyrVal: 1.558 ± 0.018	0.406TyrTrp: 0.406 ± 0.01	0.934TyrTyr: 0.934 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8771 proteins (4524954 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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