Dibothriocephalus latus (Fish tapeworm) (Diphyllobothrium latum)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda; Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Dibothriocephalus

Average proteome isoelectric point is 6.63

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 19927 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A3P7LJM4|A0A3P7LJM4_DIBLA Mediator of RNA polymerase II transcription subunit 8 OS=Dibothriocephalus latus OX=60516 GN=MED8 PE=3 SV=1
MM1 pKa = 7.94DD2 pKa = 3.13VTEE5 pKa = 4.39TVEE8 pKa = 3.73ITSPVLQVNDD18 pKa = 3.77TQTSKK23 pKa = 10.99LVPPQGSVTTSVPSTFLPDD42 pKa = 4.06DD43 pKa = 4.7LGSTTPMMPTEE54 pKa = 4.52DD55 pKa = 3.38SAVTVTEE62 pKa = 4.16TVPVSTMEE70 pKa = 4.18SLSTEE75 pKa = 4.26SEE77 pKa = 4.61TVASIPNVTSEE88 pKa = 3.99IPRR91 pKa = 11.84VSDD94 pKa = 3.01IVVTIPSTEE103 pKa = 4.16AYY105 pKa = 8.8VSSVATEE112 pKa = 4.59TIPSTEE118 pKa = 4.18EE119 pKa = 3.61LATAPLSTSEE129 pKa = 4.43IPDD132 pKa = 3.69TNMSAMQTPSVPTVISTAMPEE153 pKa = 4.62LIGSTATTTTAGTTTDD169 pKa = 3.32VPEE172 pKa = 5.31PDD174 pKa = 3.71LAMTTDD180 pKa = 3.25TAVPVISTGPQTGQTDD196 pKa = 4.12PPTVTTASTPRR207 pKa = 11.84LEE209 pKa = 4.75VSTLPPSVIISEE221 pKa = 4.42SGGTTFPVDD230 pKa = 3.42PFNTTRR236 pKa = 11.84SPDD239 pKa = 3.37VAGATTPKK247 pKa = 9.21STSPGLPGYY256 pKa = 10.26VLLGSAGMPDD266 pKa = 2.78WRR268 pKa = 11.84LYY270 pKa = 11.16LIMVSVIALALIMIMLIGWIITCVCMRR297 pKa = 11.84VSSSCLFYY305 pKa = 11.08YY306 pKa = 10.07YY307 pKa = 9.56ISHH310 pKa = 6.46SGYY313 pKa = 10.07IKK315 pKa = 10.53VSAIGGGAEE324 pKa = 3.77

Molecular weight: 33.61 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A3P7MPL3|A0A3P7MPL3_DIBLA PKD_channel domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS13546 PE=3 SV=1
MM1 pKa = 8.19RR2 pKa = 11.84ITRR5 pKa = 11.84IPQRR9 pKa = 11.84KK10 pKa = 8.35FLPKK14 pKa = 10.23NPLLRR19 pKa = 11.84IHH21 pKa = 5.89QLQRR25 pKa = 11.84TKK27 pKa = 10.8SRR29 pKa = 11.84RR30 pKa = 11.84QLRR33 pKa = 11.84TKK35 pKa = 10.24RR36 pKa = 11.84IPVRR40 pKa = 11.84KK41 pKa = 8.49FQSKK45 pKa = 10.06HH46 pKa = 5.4PSLSIHH52 pKa = 5.23QLQRR56 pKa = 11.84AKK58 pKa = 10.85LL59 pKa = 3.62

Molecular weight: 7.26 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19927

0

19927

4139272

29

3531

207.7

23.1

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.542 ± 0.018

2.133 ± 0.012

5.276 ± 0.018

6.217 ± 0.023

4.253 ± 0.017

5.434 ± 0.019

2.33 ± 0.011

4.821 ± 0.017

4.949 ± 0.02

10.127 ± 0.027

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.353 ± 0.014

3.892 ± 0.011

5.659 ± 0.019

3.98 ± 0.015

5.965 ± 0.016

8.506 ± 0.026

5.834 ± 0.014

6.424 ± 0.016

1.107 ± 0.006

2.737 ± 0.011
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski