Amino acid dipepetide frequency for Thika virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.144AlaAla: 3.144 ± 0.0
0.349AlaCys: 0.349 ± 0.0
1.397AlaAsp: 1.397 ± 0.0
3.493AlaGlu: 3.493 ± 0.0
2.794AlaPhe: 2.794 ± 0.0
1.746AlaGly: 1.746 ± 0.0
1.397AlaHis: 1.397 ± 0.0
7.335AlaIle: 7.335 ± 0.0
3.493AlaLys: 3.493 ± 0.0
3.842AlaLeu: 3.842 ± 0.0
2.445AlaMet: 2.445 ± 0.0
3.842AlaAsn: 3.842 ± 0.0
2.445AlaPro: 2.445 ± 0.0
3.144AlaGln: 3.144 ± 0.0
2.445AlaArg: 2.445 ± 0.0
2.794AlaSer: 2.794 ± 0.0
3.493AlaThr: 3.493 ± 0.0
2.445AlaVal: 2.445 ± 0.0
0.699AlaTrp: 0.699 ± 0.0
0.349AlaTyr: 0.349 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.699CysAla: 0.699 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.699CysAsp: 0.699 ± 0.0
0.349CysGlu: 0.349 ± 0.0
0.349CysPhe: 0.349 ± 0.0
1.397CysGly: 1.397 ± 0.0
0.349CysHis: 0.349 ± 0.0
1.746CysIle: 1.746 ± 0.0
1.746CysLys: 1.746 ± 0.0
0.699CysLeu: 0.699 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.349CysAsn: 0.349 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.349CysGln: 0.349 ± 0.0
0.349CysArg: 0.349 ± 0.0
0.699CysSer: 0.699 ± 0.0
0.699CysThr: 0.699 ± 0.0
0.699CysVal: 0.699 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.349CysTyr: 0.349 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.445AspAla: 2.445 ± 0.0
1.048AspCys: 1.048 ± 0.0
3.842AspAsp: 3.842 ± 0.0
2.794AspGlu: 2.794 ± 0.0
2.794AspPhe: 2.794 ± 0.0
2.445AspGly: 2.445 ± 0.0
1.746AspHis: 1.746 ± 0.0
6.287AspIle: 6.287 ± 0.0
3.144AspLys: 3.144 ± 0.0
5.938AspLeu: 5.938 ± 0.0
2.096AspMet: 2.096 ± 0.0
2.096AspAsn: 2.096 ± 0.0
2.445AspPro: 2.445 ± 0.0
2.096AspGln: 2.096 ± 0.0
1.746AspArg: 1.746 ± 0.0
3.493AspSer: 3.493 ± 0.0
3.144AspThr: 3.144 ± 0.0
3.493AspVal: 3.493 ± 0.0
0.0AspTrp: 0.0 ± 0.0
3.493AspTyr: 3.493 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.794GluAla: 2.794 ± 0.0
1.048GluCys: 1.048 ± 0.0
3.493GluAsp: 3.493 ± 0.0
3.842GluGlu: 3.842 ± 0.0
2.794GluPhe: 2.794 ± 0.0
3.842GluGly: 3.842 ± 0.0
1.048GluHis: 1.048 ± 0.0
2.445GluIle: 2.445 ± 0.0
2.794GluLys: 2.794 ± 0.0
4.541GluLeu: 4.541 ± 0.0
2.096GluMet: 2.096 ± 0.0
1.048GluAsn: 1.048 ± 0.0
3.493GluPro: 3.493 ± 0.0
3.144GluGln: 3.144 ± 0.0
2.096GluArg: 2.096 ± 0.0
3.144GluSer: 3.144 ± 0.0
2.445GluThr: 2.445 ± 0.0
3.842GluVal: 3.842 ± 0.0
1.746GluTrp: 1.746 ± 0.0
3.144GluTyr: 3.144 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.746PheAla: 1.746 ± 0.0
1.048PheCys: 1.048 ± 0.0
2.445PheAsp: 2.445 ± 0.0
1.746PheGlu: 1.746 ± 0.0
1.746PhePhe: 1.746 ± 0.0
2.096PheGly: 2.096 ± 0.0
0.0PheHis: 0.0 ± 0.0
4.191PheIle: 4.191 ± 0.0
2.445PheLys: 2.445 ± 0.0
2.794PheLeu: 2.794 ± 0.0
1.048PheMet: 1.048 ± 0.0
3.144PheAsn: 3.144 ± 0.0
2.445PhePro: 2.445 ± 0.0
1.048PheGln: 1.048 ± 0.0
1.397PheArg: 1.397 ± 0.0
4.541PheSer: 4.541 ± 0.0
3.493PheThr: 3.493 ± 0.0
1.746PheVal: 1.746 ± 0.0
0.349PheTrp: 0.349 ± 0.0
1.048PheTyr: 1.048 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.493GlyAla: 3.493 ± 0.0
0.349GlyCys: 0.349 ± 0.0
3.493GlyAsp: 3.493 ± 0.0
2.794GlyGlu: 2.794 ± 0.0
1.397GlyPhe: 1.397 ± 0.0
1.746GlyGly: 1.746 ± 0.0
0.699GlyHis: 0.699 ± 0.0
5.239GlyIle: 5.239 ± 0.0
2.096GlyLys: 2.096 ± 0.0
2.794GlyLeu: 2.794 ± 0.0
2.096GlyMet: 2.096 ± 0.0
4.541GlyAsn: 4.541 ± 0.0
1.048GlyPro: 1.048 ± 0.0
2.445GlyGln: 2.445 ± 0.0
1.397GlyArg: 1.397 ± 0.0
2.445GlySer: 2.445 ± 0.0
3.493GlyThr: 3.493 ± 0.0
2.794GlyVal: 2.794 ± 0.0
0.349GlyTrp: 0.349 ± 0.0
2.794GlyTyr: 2.794 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.048HisAla: 1.048 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.096HisAsp: 2.096 ± 0.0
1.746HisGlu: 1.746 ± 0.0
1.048HisPhe: 1.048 ± 0.0
0.699HisGly: 0.699 ± 0.0
0.699HisHis: 0.699 ± 0.0
2.445HisIle: 2.445 ± 0.0
1.746HisLys: 1.746 ± 0.0
1.746HisLeu: 1.746 ± 0.0
0.699HisMet: 0.699 ± 0.0
1.746HisAsn: 1.746 ± 0.0
0.699HisPro: 0.699 ± 0.0
1.397HisGln: 1.397 ± 0.0
1.048HisArg: 1.048 ± 0.0
0.699HisSer: 0.699 ± 0.0
1.746HisThr: 1.746 ± 0.0
3.144HisVal: 3.144 ± 0.0
0.699HisTrp: 0.699 ± 0.0
0.349HisTyr: 0.349 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.287IleAla: 6.287 ± 0.0
0.699IleCys: 0.699 ± 0.0
4.541IleAsp: 4.541 ± 0.0
7.335IleGlu: 7.335 ± 0.0
2.445IlePhe: 2.445 ± 0.0
4.89IleGly: 4.89 ± 0.0
2.794IleHis: 2.794 ± 0.0
4.89IleIle: 4.89 ± 0.0
6.986IleLys: 6.986 ± 0.0
3.493IleLeu: 3.493 ± 0.0
3.493IleMet: 3.493 ± 0.0
7.335IleAsn: 7.335 ± 0.0
3.144IlePro: 3.144 ± 0.0
3.493IleGln: 3.493 ± 0.0
2.445IleArg: 2.445 ± 0.0
5.589IleSer: 5.589 ± 0.0
8.034IleThr: 8.034 ± 0.0
3.842IleVal: 3.842 ± 0.0
0.699IleTrp: 0.699 ± 0.0
6.636IleTyr: 6.636 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.493LysAla: 3.493 ± 0.0
0.0LysCys: 0.0 ± 0.0
4.191LysAsp: 4.191 ± 0.0
4.191LysGlu: 4.191 ± 0.0
3.144LysPhe: 3.144 ± 0.0
0.699LysGly: 0.699 ± 0.0
2.096LysHis: 2.096 ± 0.0
6.986LysIle: 6.986 ± 0.0
4.89LysLys: 4.89 ± 0.0
6.986LysLeu: 6.986 ± 0.0
2.096LysMet: 2.096 ± 0.0
2.445LysAsn: 2.445 ± 0.0
2.794LysPro: 2.794 ± 0.0
3.144LysGln: 3.144 ± 0.0
3.842LysArg: 3.842 ± 0.0
3.842LysSer: 3.842 ± 0.0
4.541LysThr: 4.541 ± 0.0
3.493LysVal: 3.493 ± 0.0
0.0LysTrp: 0.0 ± 0.0
3.842LysTyr: 3.842 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.541LeuAla: 4.541 ± 0.0
0.699LeuCys: 0.699 ± 0.0
2.794LeuAsp: 2.794 ± 0.0
4.191LeuGlu: 4.191 ± 0.0
4.541LeuPhe: 4.541 ± 0.0
1.397LeuGly: 1.397 ± 0.0
2.096LeuHis: 2.096 ± 0.0
4.191LeuIle: 4.191 ± 0.0
3.144LeuLys: 3.144 ± 0.0
6.287LeuLeu: 6.287 ± 0.0
2.096LeuMet: 2.096 ± 0.0
3.842LeuAsn: 3.842 ± 0.0
3.842LeuPro: 3.842 ± 0.0
2.445LeuGln: 2.445 ± 0.0
2.096LeuArg: 2.096 ± 0.0
8.034LeuSer: 8.034 ± 0.0
6.287LeuThr: 6.287 ± 0.0
5.239LeuVal: 5.239 ± 0.0
0.699LeuTrp: 0.699 ± 0.0
4.541LeuTyr: 4.541 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.699MetAla: 0.699 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.794MetAsp: 2.794 ± 0.0
1.746MetGlu: 1.746 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.397MetGly: 1.397 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.445MetIle: 2.445 ± 0.0
2.096MetLys: 2.096 ± 0.0
2.445MetLeu: 2.445 ± 0.0
0.349MetMet: 0.349 ± 0.0
1.048MetAsn: 1.048 ± 0.0
1.397MetPro: 1.397 ± 0.0
1.048MetGln: 1.048 ± 0.0
1.048MetArg: 1.048 ± 0.0
2.794MetSer: 2.794 ± 0.0
2.445MetThr: 2.445 ± 0.0
1.048MetVal: 1.048 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.096MetTyr: 2.096 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.746AsnAla: 1.746 ± 0.0
0.349AsnCys: 0.349 ± 0.0
3.144AsnAsp: 3.144 ± 0.0
2.445AsnGlu: 2.445 ± 0.0
2.445AsnPhe: 2.445 ± 0.0
4.191AsnGly: 4.191 ± 0.0
2.096AsnHis: 2.096 ± 0.0
7.684AsnIle: 7.684 ± 0.0
3.842AsnLys: 3.842 ± 0.0
5.589AsnLeu: 5.589 ± 0.0
1.048AsnMet: 1.048 ± 0.0
7.335AsnAsn: 7.335 ± 0.0
4.89AsnPro: 4.89 ± 0.0
2.794AsnGln: 2.794 ± 0.0
2.096AsnArg: 2.096 ± 0.0
4.541AsnSer: 4.541 ± 0.0
4.191AsnThr: 4.191 ± 0.0
3.493AsnVal: 3.493 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
1.746AsnTyr: 1.746 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.746ProAla: 1.746 ± 0.0
0.699ProCys: 0.699 ± 0.0
3.493ProAsp: 3.493 ± 0.0
2.794ProGlu: 2.794 ± 0.0
1.048ProPhe: 1.048 ± 0.0
1.397ProGly: 1.397 ± 0.0
1.746ProHis: 1.746 ± 0.0
2.794ProIle: 2.794 ± 0.0
2.096ProLys: 2.096 ± 0.0
4.191ProLeu: 4.191 ± 0.0
0.699ProMet: 0.699 ± 0.0
2.794ProAsn: 2.794 ± 0.0
0.349ProPro: 0.349 ± 0.0
1.397ProGln: 1.397 ± 0.0
1.048ProArg: 1.048 ± 0.0
3.493ProSer: 3.493 ± 0.0
4.89ProThr: 4.89 ± 0.0
2.794ProVal: 2.794 ± 0.0
1.048ProTrp: 1.048 ± 0.0
3.144ProTyr: 3.144 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.493GlnAla: 3.493 ± 0.0
0.349GlnCys: 0.349 ± 0.0
1.746GlnAsp: 1.746 ± 0.0
1.746GlnGlu: 1.746 ± 0.0
2.794GlnPhe: 2.794 ± 0.0
2.096GlnGly: 2.096 ± 0.0
0.699GlnHis: 0.699 ± 0.0
2.445GlnIle: 2.445 ± 0.0
2.445GlnLys: 2.445 ± 0.0
2.794GlnLeu: 2.794 ± 0.0
0.349GlnMet: 0.349 ± 0.0
2.096GlnAsn: 2.096 ± 0.0
2.794GlnPro: 2.794 ± 0.0
2.794GlnGln: 2.794 ± 0.0
1.397GlnArg: 1.397 ± 0.0
2.096GlnSer: 2.096 ± 0.0
3.842GlnThr: 3.842 ± 0.0
2.096GlnVal: 2.096 ± 0.0
1.048GlnTrp: 1.048 ± 0.0
2.794GlnTyr: 2.794 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.746ArgAla: 1.746 ± 0.0
1.746ArgCys: 1.746 ± 0.0
2.445ArgAsp: 2.445 ± 0.0
2.096ArgGlu: 2.096 ± 0.0
1.048ArgPhe: 1.048 ± 0.0
1.397ArgGly: 1.397 ± 0.0
0.699ArgHis: 0.699 ± 0.0
3.144ArgIle: 3.144 ± 0.0
3.144ArgLys: 3.144 ± 0.0
1.746ArgLeu: 1.746 ± 0.0
0.349ArgMet: 0.349 ± 0.0
2.794ArgAsn: 2.794 ± 0.0
2.794ArgPro: 2.794 ± 0.0
2.445ArgGln: 2.445 ± 0.0
1.048ArgArg: 1.048 ± 0.0
3.144ArgSer: 3.144 ± 0.0
2.794ArgThr: 2.794 ± 0.0
1.746ArgVal: 1.746 ± 0.0
0.349ArgTrp: 0.349 ± 0.0
1.746ArgTyr: 1.746 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.239SerAla: 5.239 ± 0.0
0.349SerCys: 0.349 ± 0.0
3.144SerAsp: 3.144 ± 0.0
3.144SerGlu: 3.144 ± 0.0
3.493SerPhe: 3.493 ± 0.0
4.541SerGly: 4.541 ± 0.0
1.048SerHis: 1.048 ± 0.0
5.589SerIle: 5.589 ± 0.0
5.589SerLys: 5.589 ± 0.0
3.842SerLeu: 3.842 ± 0.0
1.397SerMet: 1.397 ± 0.0
7.684SerAsn: 7.684 ± 0.0
2.096SerPro: 2.096 ± 0.0
1.746SerGln: 1.746 ± 0.0
2.096SerArg: 2.096 ± 0.0
4.541SerSer: 4.541 ± 0.0
5.589SerThr: 5.589 ± 0.0
4.89SerVal: 4.89 ± 0.0
1.048SerTrp: 1.048 ± 0.0
2.096SerTyr: 2.096 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.794ThrAla: 2.794 ± 0.0
0.699ThrCys: 0.699 ± 0.0
3.842ThrAsp: 3.842 ± 0.0
3.144ThrGlu: 3.144 ± 0.0
2.096ThrPhe: 2.096 ± 0.0
5.239ThrGly: 5.239 ± 0.0
3.493ThrHis: 3.493 ± 0.0
7.335ThrIle: 7.335 ± 0.0
6.287ThrLys: 6.287 ± 0.0
4.89ThrLeu: 4.89 ± 0.0
2.445ThrMet: 2.445 ± 0.0
5.239ThrAsn: 5.239 ± 0.0
3.144ThrPro: 3.144 ± 0.0
2.445ThrGln: 2.445 ± 0.0
3.842ThrArg: 3.842 ± 0.0
5.938ThrSer: 5.938 ± 0.0
8.732ThrThr: 8.732 ± 0.0
4.191ThrVal: 4.191 ± 0.0
0.699ThrTrp: 0.699 ± 0.0
3.144ThrTyr: 3.144 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.144ValAla: 3.144 ± 0.0
0.349ValCys: 0.349 ± 0.0
2.445ValAsp: 2.445 ± 0.0
2.794ValGlu: 2.794 ± 0.0
2.445ValPhe: 2.445 ± 0.0
2.794ValGly: 2.794 ± 0.0
0.699ValHis: 0.699 ± 0.0
4.89ValIle: 4.89 ± 0.0
4.191ValLys: 4.191 ± 0.0
4.541ValLeu: 4.541 ± 0.0
1.397ValMet: 1.397 ± 0.0
3.144ValAsn: 3.144 ± 0.0
1.746ValPro: 1.746 ± 0.0
1.746ValGln: 1.746 ± 0.0
4.191ValArg: 4.191 ± 0.0
3.493ValSer: 3.493 ± 0.0
6.287ValThr: 6.287 ± 0.0
3.493ValVal: 3.493 ± 0.0
1.048ValTrp: 1.048 ± 0.0
2.096ValTyr: 2.096 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.699TrpCys: 0.699 ± 0.0
2.794TrpAsp: 2.794 ± 0.0
0.349TrpGlu: 0.349 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.397TrpIle: 1.397 ± 0.0
0.699TrpLys: 0.699 ± 0.0
0.349TrpLeu: 0.349 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.699TrpAsn: 0.699 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.048TrpArg: 1.048 ± 0.0
0.699TrpSer: 0.699 ± 0.0
1.048TrpThr: 1.048 ± 0.0
0.349TrpVal: 0.349 ± 0.0
0.349TrpTrp: 0.349 ± 0.0
0.699TrpTyr: 0.699 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.794TyrAla: 2.794 ± 0.0
1.048TyrCys: 1.048 ± 0.0
1.746TyrAsp: 1.746 ± 0.0
2.096TyrGlu: 2.096 ± 0.0
2.096TyrPhe: 2.096 ± 0.0
3.493TyrGly: 3.493 ± 0.0
2.096TyrHis: 2.096 ± 0.0
5.589TyrIle: 5.589 ± 0.0
3.842TyrLys: 3.842 ± 0.0
3.493TyrLeu: 3.493 ± 0.0
0.349TyrMet: 0.349 ± 0.0
2.445TyrAsn: 2.445 ± 0.0
2.096TyrPro: 2.096 ± 0.0
2.794TyrGln: 2.794 ± 0.0
1.746TyrArg: 1.746 ± 0.0
3.144TyrSer: 3.144 ± 0.0
2.794TyrThr: 2.794 ± 0.0
2.096TyrVal: 2.096 ± 0.0
0.349TyrTrp: 0.349 ± 0.0
2.096TyrTyr: 2.096 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2864 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski