Escherichia coli O157:H7
Taxonomy: cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli
Average proteome isoelectric point is 6.51
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Virtual 2D-PAGE plot for 5064 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A0H3JGV4|A0A0H3JGV4_ECO57 ArsC family reductase OS=Escherichia coli O157:H7 OX=83334 GN=yffB PE=3 SV=1
MM1 pKa = 7.44PASAVGALGEE11 pKa = 3.99ASYY14 pKa = 9.98TVTANVTDD22 pKa = 3.6SAGNSNSASHH32 pKa = 6.17NVQVNTALPGVTINPVATDD51 pKa = 4.31DD52 pKa = 4.55IINAAEE58 pKa = 4.17SGNAQTISGQVTGAAAGDD76 pKa = 4.13TVTVTLGGKK85 pKa = 8.07TYY87 pKa = 9.61TATVQGNLSWSVDD100 pKa = 3.4VPAADD105 pKa = 3.36IQAIGNGNLTVNASVTNGVGNTGSGSRR132 pKa = 11.84DD133 pKa = 2.87ITIDD137 pKa = 3.15ANLPGLRR144 pKa = 11.84VDD146 pKa = 4.35TVAGDD151 pKa = 3.82DD152 pKa = 3.62VVNSIEE158 pKa = 4.1HH159 pKa = 5.69AQALVITGSSSGLAAGAALTVVINTVTYY187 pKa = 10.39AATVLADD194 pKa = 3.88GTWSVGVPAADD205 pKa = 3.51VSNWPAGTVNITVSGTNTAGTTSTITHH232 pKa = 7.3PVTVDD237 pKa = 3.69LAAVAISINTVSGDD251 pKa = 3.75DD252 pKa = 3.93VINAAEE258 pKa = 4.32KK259 pKa = 10.82GADD262 pKa = 3.54LTLSGSTSGVEE273 pKa = 3.95VGQTVTVTFGGKK285 pKa = 8.15TYY287 pKa = 9.2TATVAGDD294 pKa = 4.0GSWTTTVPAADD305 pKa = 4.09LSVLRR310 pKa = 11.84DD311 pKa = 3.12GDD313 pKa = 3.79ATVQASVSTINGNTASATHH332 pKa = 7.19AYY334 pKa = 10.04SVDD337 pKa = 3.01ATAPTLAINTIATDD351 pKa = 4.59DD352 pKa = 3.71ILNAAEE358 pKa = 4.72AGNPLTISGSSTAEE372 pKa = 3.58AGQTVTVTLNGVTYY386 pKa = 10.14SGSVQADD393 pKa = 3.91GSWSVSLPTADD404 pKa = 5.04LSNLTASQYY413 pKa = 9.36TVSASVSDD421 pKa = 3.78KK422 pKa = 11.25AGNPASANHH431 pKa = 6.08GLAVDD436 pKa = 3.97LTVPVLTINTVSGDD450 pKa = 4.12DD451 pKa = 3.78IINAAEE457 pKa = 4.25HH458 pKa = 5.75GQALVISGSSTGGEE472 pKa = 3.97AGDD475 pKa = 4.3VITVTLNSKK484 pKa = 9.07TYY486 pKa = 8.33TTMLDD491 pKa = 3.31ASGNWSVGVPAADD504 pKa = 3.56VTALGSGPQTITAAITDD521 pKa = 3.86AAGNSDD527 pKa = 3.71DD528 pKa = 4.08ASRR531 pKa = 11.84TVTVNLAAPTIGINTIATDD550 pKa = 3.91DD551 pKa = 4.12VIKK554 pKa = 10.14ATEE557 pKa = 4.24KK558 pKa = 11.03GADD561 pKa = 3.63LQITGTSNQPAGTTITVTLNGQNYY585 pKa = 7.47TATTDD590 pKa = 4.1SNGNWSATVPASAVSALGEE609 pKa = 3.94ANYY612 pKa = 9.58TVTANVTDD620 pKa = 3.59TAGNSNSASHH630 pKa = 6.21NVLVNSALPAVTINAVATDD649 pKa = 4.51DD650 pKa = 4.55IINAAEE656 pKa = 4.17SGNAQTISGQVTGAAQGDD674 pKa = 4.58TVTVTLGGNTYY685 pKa = 8.71TATVQSNLSWSVDD698 pKa = 3.37VPAADD703 pKa = 3.56IQALGNGDD711 pKa = 3.76LTVNASVTNGVGNTGSGSRR730 pKa = 11.84DD731 pKa = 2.87ITIDD735 pKa = 3.15ANLPGLRR742 pKa = 11.84VDD744 pKa = 4.35TVAGDD749 pKa = 3.81DD750 pKa = 3.91VINSIEE756 pKa = 4.21HH757 pKa = 5.23NQALVITGSSSGLTAGTALTVEE779 pKa = 4.73INNVTYY785 pKa = 10.43GATVLADD792 pKa = 3.95GTWSLGVPAVDD803 pKa = 3.7VSNWPAGTVNITVSGTNSAGTTSTITHH830 pKa = 7.3PVTVDD835 pKa = 3.49LAGVAITINTLSGDD849 pKa = 3.81DD850 pKa = 3.95VINAVEE856 pKa = 4.13KK857 pKa = 11.32GEE859 pKa = 4.14TLVVSGSTSGVEE871 pKa = 3.77AGQTVTVTFGGKK883 pKa = 9.83NYY885 pKa = 7.25TTTVEE890 pKa = 4.98ANGSWTVNVPPADD903 pKa = 3.78LAALPDD909 pKa = 3.86GAGNVQASVSNINGNSAQADD929 pKa = 3.73RR930 pKa = 11.84AYY932 pKa = 10.96SVDD935 pKa = 2.95ATAPLVTINTIASDD949 pKa = 4.42DD950 pKa = 3.62ILNVSEE956 pKa = 4.63AGAGITISGTTTAQAGQTLTVTLNNNTYY984 pKa = 8.26QTTVLADD991 pKa = 3.75GTWSVNVPAADD1002 pKa = 3.95LSGLTASSYY1011 pKa = 10.54TVTATVSDD1019 pKa = 3.9KK1020 pKa = 11.44AGNPASADD1028 pKa = 3.22HH1029 pKa = 6.69ALVVDD1034 pKa = 4.01ITAPDD1039 pKa = 3.49LTINTVAGDD1048 pKa = 4.2DD1049 pKa = 3.74IINAIEE1055 pKa = 4.28HH1056 pKa = 5.36GQALVVSGTSTGAAAGDD1073 pKa = 4.01VVTVTLNGKK1082 pKa = 9.7NYY1084 pKa = 7.54TTTLDD1089 pKa = 3.65ASGNWSVGIPAADD1102 pKa = 3.53VTALATGSQTITASLSDD1119 pKa = 3.33RR1120 pKa = 11.84AGNSDD1125 pKa = 3.71STTHH1129 pKa = 7.08DD1130 pKa = 3.3VTVDD1134 pKa = 3.33LSGPTLTINTVSGDD1148 pKa = 4.12DD1149 pKa = 3.97IINAAEE1155 pKa = 3.94IVVAQTISGQVTGTAVAGNTVIVTIGGNQYY1185 pKa = 10.84NATVQSDD1192 pKa = 3.96LSWSVSVPANVLQALGNGEE1211 pKa = 4.16LTISASLTNSANNTGTATHH1230 pKa = 7.39DD1231 pKa = 3.24IVIDD1235 pKa = 3.9ANLPGLRR1242 pKa = 11.84VDD1244 pKa = 4.35TVAGDD1249 pKa = 3.81DD1250 pKa = 3.91VINSIEE1256 pKa = 4.13HH1257 pKa = 4.93TQALVITGSSSGLAAGAALTVVINSVTYY1285 pKa = 10.15GATVLADD1292 pKa = 3.94GSWSVGVPVADD1303 pKa = 3.62VTNWPAGTVNIAVSGTNTAGTTTSISHH1330 pKa = 6.92PVTVDD1335 pKa = 3.68LAAVAITINTLSTDD1349 pKa = 3.69DD1350 pKa = 4.49VINAAEE1356 pKa = 4.55KK1357 pKa = 10.96GSDD1360 pKa = 3.53LQLSGTTSGVEE1371 pKa = 3.62AGQTITVIFGGKK1383 pKa = 9.63SYY1385 pKa = 7.66TTTVAADD1392 pKa = 3.74NTWGLTIPAVDD1403 pKa = 3.86VATLPDD1409 pKa = 3.53GAANVQASVSNVAGNSTQATHH1430 pKa = 7.16AYY1432 pKa = 9.9SVDD1435 pKa = 2.95ATAPSVTINTIATDD1449 pKa = 4.63DD1450 pKa = 3.71ILNAAEE1456 pKa = 4.72AGSALTISGTSTAEE1470 pKa = 3.61AGQTVTVTLNGVNYY1484 pKa = 10.02SGNVQADD1491 pKa = 4.15GSWSVSVPTGDD1502 pKa = 4.16LASLTASSYY1511 pKa = 9.46TVNASVSDD1519 pKa = 3.64KK1520 pKa = 11.09ARR1522 pKa = 11.84NSASATHH1529 pKa = 6.51NLTVDD1534 pKa = 3.98LAAPVVTINTVAGDD1548 pKa = 4.24DD1549 pKa = 4.02IINATEE1555 pKa = 4.14HH1556 pKa = 5.81GQAQIISGSATGATTGNTVSVTIGTTTYY1584 pKa = 7.97TTVLDD1589 pKa = 4.74ANGNWSIGVPASVISALAQGDD1610 pKa = 3.82VTITATVTDD1619 pKa = 3.81SAGNSGTASHH1629 pKa = 6.58TVTVALGAPVLAINTIAVDD1648 pKa = 4.37DD1649 pKa = 5.13IINAAEE1655 pKa = 4.3KK1656 pKa = 10.68GADD1659 pKa = 3.58LAITGTSNQPAGTQITVTLNGQNYY1683 pKa = 6.85TTTADD1688 pKa = 3.59ASGNWSVTVPASRR1701 pKa = 11.84VSALGEE1707 pKa = 3.63ATYY1710 pKa = 9.95TVTAAATDD1718 pKa = 3.59ADD1720 pKa = 4.53GNSGSASHH1728 pKa = 6.36NVQVNTALPGVTINVVATDD1747 pKa = 4.54DD1748 pKa = 4.23IINAAEE1754 pKa = 4.23AGVEE1758 pKa = 4.04QTISGQVTGAAAGDD1772 pKa = 4.13TVTVTLGGATYY1783 pKa = 8.64TATVQANLSWSVDD1796 pKa = 3.57VPASALQEE1804 pKa = 4.25LGNGEE1809 pKa = 4.28LTISASVTNSVGNTGNGTRR1828 pKa = 11.84EE1829 pKa = 3.61ITIDD1833 pKa = 3.35ANLPGLRR1840 pKa = 11.84VDD1842 pKa = 4.35TVAGDD1847 pKa = 3.66DD1848 pKa = 3.46VVNIIEE1854 pKa = 4.66HH1855 pKa = 5.45GQALVITGSSSGLAAGSNVTLTINGQTYY1883 pKa = 9.17VAAVLADD1890 pKa = 3.92GTWSVGVPAVDD1901 pKa = 3.75VSAWPAGSVTIAASGSTSAGNPVSVTHH1928 pKa = 6.62PVTVDD1933 pKa = 3.3LSAVAVSINAITADD1947 pKa = 3.76DD1948 pKa = 4.49VINAAEE1954 pKa = 4.35KK1955 pKa = 10.58GAALTLSGSTSGVEE1969 pKa = 3.77AGQTVTVTFGGKK1981 pKa = 7.95TYY1983 pKa = 10.71SATVAANGSWSTSVPAADD2001 pKa = 3.37MAALRR2006 pKa = 11.84DD2007 pKa = 3.8GDD2009 pKa = 4.11ASAQASVSNVNGNSATTTHH2028 pKa = 7.26AYY2030 pKa = 10.19SVDD2033 pKa = 3.09ASAPTVTINTIAGDD2047 pKa = 4.54DD2048 pKa = 3.61ILNAAEE2054 pKa = 4.67AGAALTITGSSTAEE2068 pKa = 3.71AGQTVTVTLNGTNYY2082 pKa = 9.7TGTVQTDD2089 pKa = 4.05GSWSVSVPSADD2100 pKa = 4.48LSTLTASNYY2109 pKa = 7.36TVNAAVSDD2117 pKa = 3.97KK2118 pKa = 10.97AGNPASVNHH2127 pKa = 6.46NLTVDD2132 pKa = 3.64TSVPVVTINTVAGDD2146 pKa = 3.83DD2147 pKa = 4.05VINATEE2153 pKa = 3.97HH2154 pKa = 5.77AQAQIISGSATGAATGSTVTVTIGTNTFTTVLDD2187 pKa = 4.14ASGNWSVGVPASVVSALANGTVTINASVTDD2217 pKa = 3.65AGGNSGSATHH2227 pKa = 5.86QVTVNTGLPTITFNAISGDD2246 pKa = 3.81NILNADD2252 pKa = 4.11EE2253 pKa = 5.07KK2254 pKa = 10.79GQPLTISGGSTGLATGAQVTVTLNGHH2280 pKa = 6.08NYY2282 pKa = 10.36SATTDD2287 pKa = 3.33ASGNWTLTVPVSDD2300 pKa = 5.21LAALGQANYY2309 pKa = 8.71TVSASATSAAGNTASSQANLLVDD2332 pKa = 3.63SGLPDD2337 pKa = 3.33VTINTVAGDD2346 pKa = 4.31DD2347 pKa = 4.03IINAAEE2353 pKa = 4.17AGADD2357 pKa = 3.48QTISGVVTRR2366 pKa = 11.84AAAGDD2371 pKa = 4.08TVTVTLGGNTYY2382 pKa = 8.71TATVQSNLSWSVSVPTADD2400 pKa = 4.63LQALGNGDD2408 pKa = 3.84LTITASVTNANGNTGSGTRR2427 pKa = 11.84DD2428 pKa = 2.82ITIDD2432 pKa = 3.3ANLPGLRR2439 pKa = 11.84VDD2441 pKa = 4.43TVAGDD2446 pKa = 4.49DD2447 pKa = 3.29IVNSIEE2453 pKa = 4.04HH2454 pKa = 5.74GQALVITGGSSGLNAGAVLTVTINSVAYY2482 pKa = 9.91SATVQADD2489 pKa = 3.91GSWSVGIPAANVSAWPAGPLTVEE2512 pKa = 3.95VDD2514 pKa = 4.0GQSSANNPVSVSHH2527 pKa = 7.3PFTVDD2532 pKa = 3.14LTAVAISINTVASDD2546 pKa = 3.82DD2547 pKa = 4.22VINAAEE2553 pKa = 4.47KK2554 pKa = 9.45GTNLTLSGSTSGIEE2568 pKa = 3.9SGQTVTVTFGGKK2580 pKa = 8.12TYY2582 pKa = 9.15TASVAANGSWSVNVPAADD2600 pKa = 3.91LATLPEE2606 pKa = 4.39GAANVQASVSSASGNSASATHH2627 pKa = 7.19AYY2629 pKa = 10.12SVDD2632 pKa = 3.09ASAPTLTINTIASDD2646 pKa = 4.7DD2647 pKa = 3.69ILNAAEE2653 pKa = 4.65AGSPLTISGTSTAEE2667 pKa = 3.72TGQTVTVTLNGATYY2681 pKa = 9.4TGTVQADD2688 pKa = 4.14GSWSVSVPTSALGALNASNYY2708 pKa = 7.71TVSATVNDD2716 pKa = 3.94KK2717 pKa = 11.19AGNPGSASHH2726 pKa = 6.53NLAVDD2731 pKa = 3.85TTAPVLTINTVAGDD2745 pKa = 4.32DD2746 pKa = 4.09IINDD2750 pKa = 3.8AEE2752 pKa = 4.25HH2753 pKa = 6.49AQALVISGTSSGGEE2767 pKa = 3.78AGDD2770 pKa = 3.64VVSVVLNGKK2779 pKa = 7.75TYY2781 pKa = 7.52TTTLDD2786 pKa = 3.47ASGNWSVGVPAADD2799 pKa = 3.56VTALGSGAQTITASVSDD2816 pKa = 3.7RR2817 pKa = 11.84AGNSDD2822 pKa = 3.58DD2823 pKa = 3.77ASRR2826 pKa = 11.84TVTVSLSAPVISINTIAGDD2845 pKa = 3.76DD2846 pKa = 4.09VINATEE2852 pKa = 4.27KK2853 pKa = 11.11GSDD2856 pKa = 3.43LALSGTSDD2864 pKa = 3.52QPAGTAITVTLNGQNYY2880 pKa = 9.92SATTDD2885 pKa = 3.23ASGNWSVTVPASAVSALGEE2904 pKa = 3.91ATYY2907 pKa = 11.09SVTASVTNAQGNSSTASHH2925 pKa = 5.96NVQVNTALPGITINPVATDD2944 pKa = 4.19DD2945 pKa = 4.85IINASEE2951 pKa = 4.22AGSAQTISGQVTGAAAGSTVTVEE2974 pKa = 4.56LGGKK2978 pKa = 7.88TYY2980 pKa = 9.63TATVQADD2987 pKa = 3.79LSWNVSVPAADD2998 pKa = 3.43WQALGNGEE3006 pKa = 4.29LTVNASVTNAVGNTGSGTRR3025 pKa = 11.84DD3026 pKa = 2.92ITIDD3030 pKa = 3.14ASLPGLRR3037 pKa = 11.84VDD3039 pKa = 4.43TVAGDD3044 pKa = 3.66DD3045 pKa = 3.46VVNIIEE3051 pKa = 4.3HH3052 pKa = 6.05AQAQVITGSSSGFAAGTALTVVINNQTYY3080 pKa = 10.36AATVLANGSWSVGVPATDD3098 pKa = 3.37VSNWPAGTLNITVSGANSAGTQTSITHH3125 pKa = 7.08PLTVDD3130 pKa = 3.79LTAVAISMNSITSDD3144 pKa = 3.5DD3145 pKa = 4.85AINAAEE3151 pKa = 4.55KK3152 pKa = 10.6GAALTLSGSTSGVEE3166 pKa = 3.77AGQTVTVTFGGKK3178 pKa = 8.19TYY3180 pKa = 7.32TTTVAANGSWSTTVPAADD3198 pKa = 3.89LAALRR3203 pKa = 11.84DD3204 pKa = 3.96GDD3206 pKa = 4.02ASAQVRR3212 pKa = 11.84VTNVNGNSATATHH3225 pKa = 7.16EE3226 pKa = 4.04YY3227 pKa = 10.45SVDD3230 pKa = 3.35SAAPTVTINTIASDD3244 pKa = 4.0NIINASEE3251 pKa = 3.81AAAGVTVSGTSTAQTGQTLTVTLNGTNYY3279 pKa = 7.82QTTVQTDD3286 pKa = 4.18GSWSLTLPASDD3297 pKa = 4.15LTALANNGYY3306 pKa = 7.64TLTATVSDD3314 pKa = 3.89LAGNLGSASKK3324 pKa = 10.77GVTVDD3329 pKa = 3.04TTAPVISFNTVAGDD3343 pKa = 3.64DD3344 pKa = 3.91VINNVEE3350 pKa = 4.63HH3351 pKa = 6.5IQAQIISGTATGAVAGDD3368 pKa = 3.53RR3369 pKa = 11.84LVVTIAGQQYY3379 pKa = 7.76VTSTDD3384 pKa = 3.21ASGNWSVGVPASVISGLADD3403 pKa = 3.3GTVTISATITDD3414 pKa = 3.91SAGNSSTQTHH3424 pKa = 5.27NVQVNTAAVSLSVSTISGDD3443 pKa = 3.64NLINAAEE3450 pKa = 4.43AGSALTLSGTGTNFATGTVVTVLLNGKK3477 pKa = 9.36GYY3479 pKa = 10.57SATIQSNGSWSVNVPAADD3497 pKa = 3.49VAALSDD3503 pKa = 3.68GTSYY3507 pKa = 10.22TVSASAQDD3515 pKa = 3.48SAGNGNSSTQTHH3527 pKa = 5.27NVQVNTAAVSLSVSTISGDD3546 pKa = 3.64NLINAAEE3553 pKa = 4.43AGSALTLSGTGTNFATGTVVTVLLNGKK3580 pKa = 9.36GYY3582 pKa = 10.57SATIQSNGSWSVNVPAADD3600 pKa = 3.49VAALSDD3606 pKa = 3.68GTSYY3610 pKa = 10.22TVSASAQDD3618 pKa = 3.59SAGNSATASRR3628 pKa = 11.84SVAVDD3633 pKa = 3.14LTAPVISINTVSTDD3647 pKa = 3.12DD3648 pKa = 3.8RR3649 pKa = 11.84LNAAEE3654 pKa = 3.97QQQPLTLNGSTSAEE3668 pKa = 4.03VGQTVTVTFGGKK3680 pKa = 8.15TYY3682 pKa = 9.55TATVAANGTWALNVPAVDD3700 pKa = 5.09LAALGQGAQTITASVNDD3717 pKa = 3.9RR3718 pKa = 11.84AGNPGQATHH3727 pKa = 7.23ALTVDD3732 pKa = 4.01TVAPTVTIATVAGDD3746 pKa = 4.4DD3747 pKa = 4.0IINNAEE3753 pKa = 3.86QLAGQTISGTTTAEE3767 pKa = 3.82VGQTVTVTFNGQTWSATVGSGGSWSVFIPAQQFAGLSDD3805 pKa = 3.79GSYY3808 pKa = 9.76TISATVSDD3816 pKa = 3.95QAGNPGSASRR3826 pKa = 11.84GVTLNGDD3833 pKa = 3.81VPTVTINTFAGDD3845 pKa = 3.88DD3846 pKa = 3.62VVNAAEE3852 pKa = 4.76HH3853 pKa = 6.25GSSLVISGTTTAPVGQTLTLTLNGKK3878 pKa = 7.73TYY3880 pKa = 7.33TTTVQTGGSWSYY3892 pKa = 9.75TLGSADD3898 pKa = 3.4VTALADD3904 pKa = 3.57GNAYY3908 pKa = 10.03VINASVSNAIGNTGSSNHH3926 pKa = 6.84TITVDD3931 pKa = 3.8LSAPAMGINIDD3942 pKa = 4.07SLQADD3947 pKa = 4.06TGLSASDD3954 pKa = 4.92FITSVSPVVVNGSLTAALASNEE3976 pKa = 4.05TAQISIDD3983 pKa = 4.41GGTTWTTLTVTGTTWRR3999 pKa = 11.84YY4000 pKa = 9.08NDD4002 pKa = 3.61SRR4004 pKa = 11.84TLTDD4008 pKa = 3.89GNYY4011 pKa = 9.54LYY4013 pKa = 10.1QVRR4016 pKa = 11.84VIDD4019 pKa = 3.57AAGNVGATDD4028 pKa = 3.64SQNVVIDD4035 pKa = 3.67TTAPDD4040 pKa = 3.93PAVKK4044 pKa = 9.61TIAISAITTDD4054 pKa = 3.57MGLITNDD4061 pKa = 3.33FVTSDD4066 pKa = 3.22TTLAVSGTLGATLSAGEE4083 pKa = 4.1FAQISLDD4090 pKa = 4.3GGVTWTTLTVVGTSWSYY4107 pKa = 12.16ADD4109 pKa = 3.83GHH4111 pKa = 5.91TLTDD4115 pKa = 3.66GTWNYY4120 pKa = 7.18TVRR4123 pKa = 11.84VVDD4126 pKa = 3.77LAGNVGQTATQNVVVDD4142 pKa = 4.14TTSPEE4147 pKa = 3.75AAKK4150 pKa = 10.61SITITGISDD4159 pKa = 3.47DD4160 pKa = 4.33TGTSSSDD4167 pKa = 3.5FITSDD4172 pKa = 2.79TTLTVRR4178 pKa = 11.84GVLGAALGANEE4189 pKa = 4.51FAQISTDD4196 pKa = 4.86NGATWVNVTVAADD4209 pKa = 3.63SLNWSYY4215 pKa = 11.97VDD4217 pKa = 5.47GRR4219 pKa = 11.84TLTNGTTTWQVRR4231 pKa = 11.84VVDD4234 pKa = 3.97LAGNVGATSSQSALIDD4250 pKa = 3.72TVNPAQVLTIASISTDD4266 pKa = 3.35TGSSATDD4273 pKa = 4.53FITSDD4278 pKa = 3.17TMLTLTGSLGAGLASGEE4295 pKa = 4.25VAQISLDD4302 pKa = 3.91SGATWTTLTTNGTQWTYY4319 pKa = 10.29TDD4321 pKa = 4.07SRR4323 pKa = 11.84TLTDD4327 pKa = 3.56GSYY4330 pKa = 9.49VYY4332 pKa = 9.26QVRR4335 pKa = 11.84VLDD4338 pKa = 3.99LAGNTGPVVSKK4349 pKa = 9.34TVVVDD4354 pKa = 4.5TINPTATPTIVSYY4367 pKa = 10.98TDD4369 pKa = 4.7DD4370 pKa = 3.3VGQRR4374 pKa = 11.84QGTLSSSQATDD4385 pKa = 3.09DD4386 pKa = 3.81TTPLLNGVLSAPLASGEE4403 pKa = 4.19VVYY4406 pKa = 10.08LYY4408 pKa = 10.98RR4409 pKa = 11.84NGLLLGAVTMVGALNWTYY4427 pKa = 11.25SDD4429 pKa = 3.68SGLVSGAYY4437 pKa = 8.26TYY4439 pKa = 10.34SARR4442 pKa = 11.84VVDD4445 pKa = 4.25LAGNITSSSDD4455 pKa = 3.26FVLTVDD4461 pKa = 3.64TSIPTTLAQITSQTTRR4477 pKa = 11.84DD4478 pKa = 3.54TTPIISGVITAALASGQYY4496 pKa = 9.97VEE4498 pKa = 5.26VVINGKK4504 pKa = 7.97TYY4506 pKa = 9.11TSEE4509 pKa = 3.92PGGAVVVDD4517 pKa = 4.5PAHH4520 pKa = 5.37NTWYY4524 pKa = 10.6VQLPDD4529 pKa = 3.5TDD4531 pKa = 4.29ALTVSATAYY4540 pKa = 8.73TVTAQVKK4547 pKa = 9.99SSAGNGNNANISNGTVTVNAAIDD4570 pKa = 3.9YY4571 pKa = 7.39TPTWTTASKK4580 pKa = 6.89TTAWGLTYY4588 pKa = 10.93GLDD4591 pKa = 3.58SHH4593 pKa = 6.98GMWTVLANQQVMQSTDD4609 pKa = 3.14PLTWSKK4615 pKa = 9.1TALTLYY4621 pKa = 10.65QSGNNYY4627 pKa = 7.66ATSSIADD4634 pKa = 3.54YY4635 pKa = 11.07DD4636 pKa = 4.26RR4637 pKa = 11.84NGTGDD4642 pKa = 3.91LFITRR4647 pKa = 11.84DD4648 pKa = 3.78DD4649 pKa = 4.0YY4650 pKa = 11.25GTGYY4654 pKa = 10.59INGFTNNGDD4663 pKa = 3.72GTFSSAIQVTVGTLTWYY4680 pKa = 10.71GSIVAFDD4687 pKa = 4.13KK4688 pKa = 11.49EE4689 pKa = 4.23GDD4691 pKa = 3.67GYY4693 pKa = 11.41LDD4695 pKa = 3.48FWIGDD4700 pKa = 3.47AGGPDD4705 pKa = 3.81SNTFLWNNAGTLVGNSTTSNSGGSATVGGAVTGYY4739 pKa = 10.93LSLNEE4744 pKa = 4.04GSGVDD4749 pKa = 3.93LNNDD4753 pKa = 2.79GRR4755 pKa = 11.84IDD4757 pKa = 4.34LVQHH4761 pKa = 6.43TYY4763 pKa = 11.15NLNNYY4768 pKa = 7.37YY4769 pKa = 9.35TLSSLINQGNGTFVWGQNTTNTFLSGAGSGAMSSSVSMTWADD4811 pKa = 3.44FDD4813 pKa = 5.13GDD4815 pKa = 3.43GDD4817 pKa = 3.81MDD4819 pKa = 4.6LFLPASQGRR4828 pKa = 11.84ANYY4831 pKa = 10.24GSLLFNTNGVLGCPVAVGATATTYY4855 pKa = 11.24ASQFSLAVDD4864 pKa = 3.85WNHH4867 pKa = 7.32DD4868 pKa = 3.25GLMDD4872 pKa = 3.98IARR4875 pKa = 11.84IAQTGQSYY4883 pKa = 10.48LYY4885 pKa = 9.6TNVSNASNWTQSALGGSQSGTTSGVAAMDD4914 pKa = 4.1YY4915 pKa = 10.77DD4916 pKa = 3.31WDD4918 pKa = 4.04GAVDD4922 pKa = 3.76VLVSKK4927 pKa = 10.93QSGSVFLSRR4936 pKa = 11.84NTNTVSYY4943 pKa = 8.17GTSLHH4948 pKa = 6.9LRR4950 pKa = 11.84ITDD4953 pKa = 3.67PNGINVYY4960 pKa = 10.12YY4961 pKa = 10.76GNTVKK4966 pKa = 10.68LYY4968 pKa = 9.76NSAGVLVATQIINPQSGMGVNDD4990 pKa = 3.8TSALVNFYY4998 pKa = 10.82GLNAGEE5004 pKa = 4.58TYY5006 pKa = 10.75NAVLIKK5012 pKa = 10.21STGTTASNIDD5022 pKa = 3.44QTVNTSWGGLQATDD5036 pKa = 3.18ATHH5039 pKa = 7.35AYY5041 pKa = 9.88DD5042 pKa = 4.68LSAEE5046 pKa = 4.42AGTASNNGKK5055 pKa = 9.69FVGTGYY5061 pKa = 10.92NDD5063 pKa = 3.4TFFATAGTDD5072 pKa = 3.25TYY5074 pKa = 10.75DD5075 pKa = 3.77GSGGWVYY5082 pKa = 11.38SSGTGTWLANGGMDD5096 pKa = 3.6VVDD5099 pKa = 5.1FRR5101 pKa = 11.84LSTVGVTANLSSTAAQATGFNTSTFTNIEE5130 pKa = 4.43GISGSNFNDD5139 pKa = 3.01ILTGSSGDD5147 pKa = 3.54NQLEE5151 pKa = 4.16GRR5153 pKa = 11.84GGNDD5157 pKa = 3.07TLNIGNGGHH5166 pKa = 6.71DD5167 pKa = 3.51TLLYY5171 pKa = 10.7KK5172 pKa = 10.81LLNASDD5178 pKa = 3.69ATGGNGSDD5186 pKa = 3.46VVNGFTVGTWEE5197 pKa = 4.2GTADD5201 pKa = 3.62TDD5203 pKa = 4.8RR5204 pKa = 11.84IDD5206 pKa = 4.52IRR5208 pKa = 11.84EE5209 pKa = 4.08LLQGSGYY5216 pKa = 8.74TGNGKK5221 pKa = 9.95ASYY5224 pKa = 9.92VNGVATLDD5232 pKa = 3.62AQAGNIGDD5240 pKa = 4.09FVKK5243 pKa = 9.69VTQSGSDD5250 pKa = 3.44TIVQIDD5256 pKa = 3.56RR5257 pKa = 11.84DD5258 pKa = 4.11GTGGTFATTNVVTLTGVHH5276 pKa = 6.37TDD5278 pKa = 3.89LATLLANHH5286 pKa = 6.15QLMVVV5291 pKa = 3.73
MM1 pKa = 7.44PASAVGALGEE11 pKa = 3.99ASYY14 pKa = 9.98TVTANVTDD22 pKa = 3.6SAGNSNSASHH32 pKa = 6.17NVQVNTALPGVTINPVATDD51 pKa = 4.31DD52 pKa = 4.55IINAAEE58 pKa = 4.17SGNAQTISGQVTGAAAGDD76 pKa = 4.13TVTVTLGGKK85 pKa = 8.07TYY87 pKa = 9.61TATVQGNLSWSVDD100 pKa = 3.4VPAADD105 pKa = 3.36IQAIGNGNLTVNASVTNGVGNTGSGSRR132 pKa = 11.84DD133 pKa = 2.87ITIDD137 pKa = 3.15ANLPGLRR144 pKa = 11.84VDD146 pKa = 4.35TVAGDD151 pKa = 3.82DD152 pKa = 3.62VVNSIEE158 pKa = 4.1HH159 pKa = 5.69AQALVITGSSSGLAAGAALTVVINTVTYY187 pKa = 10.39AATVLADD194 pKa = 3.88GTWSVGVPAADD205 pKa = 3.51VSNWPAGTVNITVSGTNTAGTTSTITHH232 pKa = 7.3PVTVDD237 pKa = 3.69LAAVAISINTVSGDD251 pKa = 3.75DD252 pKa = 3.93VINAAEE258 pKa = 4.32KK259 pKa = 10.82GADD262 pKa = 3.54LTLSGSTSGVEE273 pKa = 3.95VGQTVTVTFGGKK285 pKa = 8.15TYY287 pKa = 9.2TATVAGDD294 pKa = 4.0GSWTTTVPAADD305 pKa = 4.09LSVLRR310 pKa = 11.84DD311 pKa = 3.12GDD313 pKa = 3.79ATVQASVSTINGNTASATHH332 pKa = 7.19AYY334 pKa = 10.04SVDD337 pKa = 3.01ATAPTLAINTIATDD351 pKa = 4.59DD352 pKa = 3.71ILNAAEE358 pKa = 4.72AGNPLTISGSSTAEE372 pKa = 3.58AGQTVTVTLNGVTYY386 pKa = 10.14SGSVQADD393 pKa = 3.91GSWSVSLPTADD404 pKa = 5.04LSNLTASQYY413 pKa = 9.36TVSASVSDD421 pKa = 3.78KK422 pKa = 11.25AGNPASANHH431 pKa = 6.08GLAVDD436 pKa = 3.97LTVPVLTINTVSGDD450 pKa = 4.12DD451 pKa = 3.78IINAAEE457 pKa = 4.25HH458 pKa = 5.75GQALVISGSSTGGEE472 pKa = 3.97AGDD475 pKa = 4.3VITVTLNSKK484 pKa = 9.07TYY486 pKa = 8.33TTMLDD491 pKa = 3.31ASGNWSVGVPAADD504 pKa = 3.56VTALGSGPQTITAAITDD521 pKa = 3.86AAGNSDD527 pKa = 3.71DD528 pKa = 4.08ASRR531 pKa = 11.84TVTVNLAAPTIGINTIATDD550 pKa = 3.91DD551 pKa = 4.12VIKK554 pKa = 10.14ATEE557 pKa = 4.24KK558 pKa = 11.03GADD561 pKa = 3.63LQITGTSNQPAGTTITVTLNGQNYY585 pKa = 7.47TATTDD590 pKa = 4.1SNGNWSATVPASAVSALGEE609 pKa = 3.94ANYY612 pKa = 9.58TVTANVTDD620 pKa = 3.59TAGNSNSASHH630 pKa = 6.21NVLVNSALPAVTINAVATDD649 pKa = 4.51DD650 pKa = 4.55IINAAEE656 pKa = 4.17SGNAQTISGQVTGAAQGDD674 pKa = 4.58TVTVTLGGNTYY685 pKa = 8.71TATVQSNLSWSVDD698 pKa = 3.37VPAADD703 pKa = 3.56IQALGNGDD711 pKa = 3.76LTVNASVTNGVGNTGSGSRR730 pKa = 11.84DD731 pKa = 2.87ITIDD735 pKa = 3.15ANLPGLRR742 pKa = 11.84VDD744 pKa = 4.35TVAGDD749 pKa = 3.81DD750 pKa = 3.91VINSIEE756 pKa = 4.21HH757 pKa = 5.23NQALVITGSSSGLTAGTALTVEE779 pKa = 4.73INNVTYY785 pKa = 10.43GATVLADD792 pKa = 3.95GTWSLGVPAVDD803 pKa = 3.7VSNWPAGTVNITVSGTNSAGTTSTITHH830 pKa = 7.3PVTVDD835 pKa = 3.49LAGVAITINTLSGDD849 pKa = 3.81DD850 pKa = 3.95VINAVEE856 pKa = 4.13KK857 pKa = 11.32GEE859 pKa = 4.14TLVVSGSTSGVEE871 pKa = 3.77AGQTVTVTFGGKK883 pKa = 9.83NYY885 pKa = 7.25TTTVEE890 pKa = 4.98ANGSWTVNVPPADD903 pKa = 3.78LAALPDD909 pKa = 3.86GAGNVQASVSNINGNSAQADD929 pKa = 3.73RR930 pKa = 11.84AYY932 pKa = 10.96SVDD935 pKa = 2.95ATAPLVTINTIASDD949 pKa = 4.42DD950 pKa = 3.62ILNVSEE956 pKa = 4.63AGAGITISGTTTAQAGQTLTVTLNNNTYY984 pKa = 8.26QTTVLADD991 pKa = 3.75GTWSVNVPAADD1002 pKa = 3.95LSGLTASSYY1011 pKa = 10.54TVTATVSDD1019 pKa = 3.9KK1020 pKa = 11.44AGNPASADD1028 pKa = 3.22HH1029 pKa = 6.69ALVVDD1034 pKa = 4.01ITAPDD1039 pKa = 3.49LTINTVAGDD1048 pKa = 4.2DD1049 pKa = 3.74IINAIEE1055 pKa = 4.28HH1056 pKa = 5.36GQALVVSGTSTGAAAGDD1073 pKa = 4.01VVTVTLNGKK1082 pKa = 9.7NYY1084 pKa = 7.54TTTLDD1089 pKa = 3.65ASGNWSVGIPAADD1102 pKa = 3.53VTALATGSQTITASLSDD1119 pKa = 3.33RR1120 pKa = 11.84AGNSDD1125 pKa = 3.71STTHH1129 pKa = 7.08DD1130 pKa = 3.3VTVDD1134 pKa = 3.33LSGPTLTINTVSGDD1148 pKa = 4.12DD1149 pKa = 3.97IINAAEE1155 pKa = 3.94IVVAQTISGQVTGTAVAGNTVIVTIGGNQYY1185 pKa = 10.84NATVQSDD1192 pKa = 3.96LSWSVSVPANVLQALGNGEE1211 pKa = 4.16LTISASLTNSANNTGTATHH1230 pKa = 7.39DD1231 pKa = 3.24IVIDD1235 pKa = 3.9ANLPGLRR1242 pKa = 11.84VDD1244 pKa = 4.35TVAGDD1249 pKa = 3.81DD1250 pKa = 3.91VINSIEE1256 pKa = 4.13HH1257 pKa = 4.93TQALVITGSSSGLAAGAALTVVINSVTYY1285 pKa = 10.15GATVLADD1292 pKa = 3.94GSWSVGVPVADD1303 pKa = 3.62VTNWPAGTVNIAVSGTNTAGTTTSISHH1330 pKa = 6.92PVTVDD1335 pKa = 3.68LAAVAITINTLSTDD1349 pKa = 3.69DD1350 pKa = 4.49VINAAEE1356 pKa = 4.55KK1357 pKa = 10.96GSDD1360 pKa = 3.53LQLSGTTSGVEE1371 pKa = 3.62AGQTITVIFGGKK1383 pKa = 9.63SYY1385 pKa = 7.66TTTVAADD1392 pKa = 3.74NTWGLTIPAVDD1403 pKa = 3.86VATLPDD1409 pKa = 3.53GAANVQASVSNVAGNSTQATHH1430 pKa = 7.16AYY1432 pKa = 9.9SVDD1435 pKa = 2.95ATAPSVTINTIATDD1449 pKa = 4.63DD1450 pKa = 3.71ILNAAEE1456 pKa = 4.72AGSALTISGTSTAEE1470 pKa = 3.61AGQTVTVTLNGVNYY1484 pKa = 10.02SGNVQADD1491 pKa = 4.15GSWSVSVPTGDD1502 pKa = 4.16LASLTASSYY1511 pKa = 9.46TVNASVSDD1519 pKa = 3.64KK1520 pKa = 11.09ARR1522 pKa = 11.84NSASATHH1529 pKa = 6.51NLTVDD1534 pKa = 3.98LAAPVVTINTVAGDD1548 pKa = 4.24DD1549 pKa = 4.02IINATEE1555 pKa = 4.14HH1556 pKa = 5.81GQAQIISGSATGATTGNTVSVTIGTTTYY1584 pKa = 7.97TTVLDD1589 pKa = 4.74ANGNWSIGVPASVISALAQGDD1610 pKa = 3.82VTITATVTDD1619 pKa = 3.81SAGNSGTASHH1629 pKa = 6.58TVTVALGAPVLAINTIAVDD1648 pKa = 4.37DD1649 pKa = 5.13IINAAEE1655 pKa = 4.3KK1656 pKa = 10.68GADD1659 pKa = 3.58LAITGTSNQPAGTQITVTLNGQNYY1683 pKa = 6.85TTTADD1688 pKa = 3.59ASGNWSVTVPASRR1701 pKa = 11.84VSALGEE1707 pKa = 3.63ATYY1710 pKa = 9.95TVTAAATDD1718 pKa = 3.59ADD1720 pKa = 4.53GNSGSASHH1728 pKa = 6.36NVQVNTALPGVTINVVATDD1747 pKa = 4.54DD1748 pKa = 4.23IINAAEE1754 pKa = 4.23AGVEE1758 pKa = 4.04QTISGQVTGAAAGDD1772 pKa = 4.13TVTVTLGGATYY1783 pKa = 8.64TATVQANLSWSVDD1796 pKa = 3.57VPASALQEE1804 pKa = 4.25LGNGEE1809 pKa = 4.28LTISASVTNSVGNTGNGTRR1828 pKa = 11.84EE1829 pKa = 3.61ITIDD1833 pKa = 3.35ANLPGLRR1840 pKa = 11.84VDD1842 pKa = 4.35TVAGDD1847 pKa = 3.66DD1848 pKa = 3.46VVNIIEE1854 pKa = 4.66HH1855 pKa = 5.45GQALVITGSSSGLAAGSNVTLTINGQTYY1883 pKa = 9.17VAAVLADD1890 pKa = 3.92GTWSVGVPAVDD1901 pKa = 3.75VSAWPAGSVTIAASGSTSAGNPVSVTHH1928 pKa = 6.62PVTVDD1933 pKa = 3.3LSAVAVSINAITADD1947 pKa = 3.76DD1948 pKa = 4.49VINAAEE1954 pKa = 4.35KK1955 pKa = 10.58GAALTLSGSTSGVEE1969 pKa = 3.77AGQTVTVTFGGKK1981 pKa = 7.95TYY1983 pKa = 10.71SATVAANGSWSTSVPAADD2001 pKa = 3.37MAALRR2006 pKa = 11.84DD2007 pKa = 3.8GDD2009 pKa = 4.11ASAQASVSNVNGNSATTTHH2028 pKa = 7.26AYY2030 pKa = 10.19SVDD2033 pKa = 3.09ASAPTVTINTIAGDD2047 pKa = 4.54DD2048 pKa = 3.61ILNAAEE2054 pKa = 4.67AGAALTITGSSTAEE2068 pKa = 3.71AGQTVTVTLNGTNYY2082 pKa = 9.7TGTVQTDD2089 pKa = 4.05GSWSVSVPSADD2100 pKa = 4.48LSTLTASNYY2109 pKa = 7.36TVNAAVSDD2117 pKa = 3.97KK2118 pKa = 10.97AGNPASVNHH2127 pKa = 6.46NLTVDD2132 pKa = 3.64TSVPVVTINTVAGDD2146 pKa = 3.83DD2147 pKa = 4.05VINATEE2153 pKa = 3.97HH2154 pKa = 5.77AQAQIISGSATGAATGSTVTVTIGTNTFTTVLDD2187 pKa = 4.14ASGNWSVGVPASVVSALANGTVTINASVTDD2217 pKa = 3.65AGGNSGSATHH2227 pKa = 5.86QVTVNTGLPTITFNAISGDD2246 pKa = 3.81NILNADD2252 pKa = 4.11EE2253 pKa = 5.07KK2254 pKa = 10.79GQPLTISGGSTGLATGAQVTVTLNGHH2280 pKa = 6.08NYY2282 pKa = 10.36SATTDD2287 pKa = 3.33ASGNWTLTVPVSDD2300 pKa = 5.21LAALGQANYY2309 pKa = 8.71TVSASATSAAGNTASSQANLLVDD2332 pKa = 3.63SGLPDD2337 pKa = 3.33VTINTVAGDD2346 pKa = 4.31DD2347 pKa = 4.03IINAAEE2353 pKa = 4.17AGADD2357 pKa = 3.48QTISGVVTRR2366 pKa = 11.84AAAGDD2371 pKa = 4.08TVTVTLGGNTYY2382 pKa = 8.71TATVQSNLSWSVSVPTADD2400 pKa = 4.63LQALGNGDD2408 pKa = 3.84LTITASVTNANGNTGSGTRR2427 pKa = 11.84DD2428 pKa = 2.82ITIDD2432 pKa = 3.3ANLPGLRR2439 pKa = 11.84VDD2441 pKa = 4.43TVAGDD2446 pKa = 4.49DD2447 pKa = 3.29IVNSIEE2453 pKa = 4.04HH2454 pKa = 5.74GQALVITGGSSGLNAGAVLTVTINSVAYY2482 pKa = 9.91SATVQADD2489 pKa = 3.91GSWSVGIPAANVSAWPAGPLTVEE2512 pKa = 3.95VDD2514 pKa = 4.0GQSSANNPVSVSHH2527 pKa = 7.3PFTVDD2532 pKa = 3.14LTAVAISINTVASDD2546 pKa = 3.82DD2547 pKa = 4.22VINAAEE2553 pKa = 4.47KK2554 pKa = 9.45GTNLTLSGSTSGIEE2568 pKa = 3.9SGQTVTVTFGGKK2580 pKa = 8.12TYY2582 pKa = 9.15TASVAANGSWSVNVPAADD2600 pKa = 3.91LATLPEE2606 pKa = 4.39GAANVQASVSSASGNSASATHH2627 pKa = 7.19AYY2629 pKa = 10.12SVDD2632 pKa = 3.09ASAPTLTINTIASDD2646 pKa = 4.7DD2647 pKa = 3.69ILNAAEE2653 pKa = 4.65AGSPLTISGTSTAEE2667 pKa = 3.72TGQTVTVTLNGATYY2681 pKa = 9.4TGTVQADD2688 pKa = 4.14GSWSVSVPTSALGALNASNYY2708 pKa = 7.71TVSATVNDD2716 pKa = 3.94KK2717 pKa = 11.19AGNPGSASHH2726 pKa = 6.53NLAVDD2731 pKa = 3.85TTAPVLTINTVAGDD2745 pKa = 4.32DD2746 pKa = 4.09IINDD2750 pKa = 3.8AEE2752 pKa = 4.25HH2753 pKa = 6.49AQALVISGTSSGGEE2767 pKa = 3.78AGDD2770 pKa = 3.64VVSVVLNGKK2779 pKa = 7.75TYY2781 pKa = 7.52TTTLDD2786 pKa = 3.47ASGNWSVGVPAADD2799 pKa = 3.56VTALGSGAQTITASVSDD2816 pKa = 3.7RR2817 pKa = 11.84AGNSDD2822 pKa = 3.58DD2823 pKa = 3.77ASRR2826 pKa = 11.84TVTVSLSAPVISINTIAGDD2845 pKa = 3.76DD2846 pKa = 4.09VINATEE2852 pKa = 4.27KK2853 pKa = 11.11GSDD2856 pKa = 3.43LALSGTSDD2864 pKa = 3.52QPAGTAITVTLNGQNYY2880 pKa = 9.92SATTDD2885 pKa = 3.23ASGNWSVTVPASAVSALGEE2904 pKa = 3.91ATYY2907 pKa = 11.09SVTASVTNAQGNSSTASHH2925 pKa = 5.96NVQVNTALPGITINPVATDD2944 pKa = 4.19DD2945 pKa = 4.85IINASEE2951 pKa = 4.22AGSAQTISGQVTGAAAGSTVTVEE2974 pKa = 4.56LGGKK2978 pKa = 7.88TYY2980 pKa = 9.63TATVQADD2987 pKa = 3.79LSWNVSVPAADD2998 pKa = 3.43WQALGNGEE3006 pKa = 4.29LTVNASVTNAVGNTGSGTRR3025 pKa = 11.84DD3026 pKa = 2.92ITIDD3030 pKa = 3.14ASLPGLRR3037 pKa = 11.84VDD3039 pKa = 4.43TVAGDD3044 pKa = 3.66DD3045 pKa = 3.46VVNIIEE3051 pKa = 4.3HH3052 pKa = 6.05AQAQVITGSSSGFAAGTALTVVINNQTYY3080 pKa = 10.36AATVLANGSWSVGVPATDD3098 pKa = 3.37VSNWPAGTLNITVSGANSAGTQTSITHH3125 pKa = 7.08PLTVDD3130 pKa = 3.79LTAVAISMNSITSDD3144 pKa = 3.5DD3145 pKa = 4.85AINAAEE3151 pKa = 4.55KK3152 pKa = 10.6GAALTLSGSTSGVEE3166 pKa = 3.77AGQTVTVTFGGKK3178 pKa = 8.19TYY3180 pKa = 7.32TTTVAANGSWSTTVPAADD3198 pKa = 3.89LAALRR3203 pKa = 11.84DD3204 pKa = 3.96GDD3206 pKa = 4.02ASAQVRR3212 pKa = 11.84VTNVNGNSATATHH3225 pKa = 7.16EE3226 pKa = 4.04YY3227 pKa = 10.45SVDD3230 pKa = 3.35SAAPTVTINTIASDD3244 pKa = 4.0NIINASEE3251 pKa = 3.81AAAGVTVSGTSTAQTGQTLTVTLNGTNYY3279 pKa = 7.82QTTVQTDD3286 pKa = 4.18GSWSLTLPASDD3297 pKa = 4.15LTALANNGYY3306 pKa = 7.64TLTATVSDD3314 pKa = 3.89LAGNLGSASKK3324 pKa = 10.77GVTVDD3329 pKa = 3.04TTAPVISFNTVAGDD3343 pKa = 3.64DD3344 pKa = 3.91VINNVEE3350 pKa = 4.63HH3351 pKa = 6.5IQAQIISGTATGAVAGDD3368 pKa = 3.53RR3369 pKa = 11.84LVVTIAGQQYY3379 pKa = 7.76VTSTDD3384 pKa = 3.21ASGNWSVGVPASVISGLADD3403 pKa = 3.3GTVTISATITDD3414 pKa = 3.91SAGNSSTQTHH3424 pKa = 5.27NVQVNTAAVSLSVSTISGDD3443 pKa = 3.64NLINAAEE3450 pKa = 4.43AGSALTLSGTGTNFATGTVVTVLLNGKK3477 pKa = 9.36GYY3479 pKa = 10.57SATIQSNGSWSVNVPAADD3497 pKa = 3.49VAALSDD3503 pKa = 3.68GTSYY3507 pKa = 10.22TVSASAQDD3515 pKa = 3.48SAGNGNSSTQTHH3527 pKa = 5.27NVQVNTAAVSLSVSTISGDD3546 pKa = 3.64NLINAAEE3553 pKa = 4.43AGSALTLSGTGTNFATGTVVTVLLNGKK3580 pKa = 9.36GYY3582 pKa = 10.57SATIQSNGSWSVNVPAADD3600 pKa = 3.49VAALSDD3606 pKa = 3.68GTSYY3610 pKa = 10.22TVSASAQDD3618 pKa = 3.59SAGNSATASRR3628 pKa = 11.84SVAVDD3633 pKa = 3.14LTAPVISINTVSTDD3647 pKa = 3.12DD3648 pKa = 3.8RR3649 pKa = 11.84LNAAEE3654 pKa = 3.97QQQPLTLNGSTSAEE3668 pKa = 4.03VGQTVTVTFGGKK3680 pKa = 8.15TYY3682 pKa = 9.55TATVAANGTWALNVPAVDD3700 pKa = 5.09LAALGQGAQTITASVNDD3717 pKa = 3.9RR3718 pKa = 11.84AGNPGQATHH3727 pKa = 7.23ALTVDD3732 pKa = 4.01TVAPTVTIATVAGDD3746 pKa = 4.4DD3747 pKa = 4.0IINNAEE3753 pKa = 3.86QLAGQTISGTTTAEE3767 pKa = 3.82VGQTVTVTFNGQTWSATVGSGGSWSVFIPAQQFAGLSDD3805 pKa = 3.79GSYY3808 pKa = 9.76TISATVSDD3816 pKa = 3.95QAGNPGSASRR3826 pKa = 11.84GVTLNGDD3833 pKa = 3.81VPTVTINTFAGDD3845 pKa = 3.88DD3846 pKa = 3.62VVNAAEE3852 pKa = 4.76HH3853 pKa = 6.25GSSLVISGTTTAPVGQTLTLTLNGKK3878 pKa = 7.73TYY3880 pKa = 7.33TTTVQTGGSWSYY3892 pKa = 9.75TLGSADD3898 pKa = 3.4VTALADD3904 pKa = 3.57GNAYY3908 pKa = 10.03VINASVSNAIGNTGSSNHH3926 pKa = 6.84TITVDD3931 pKa = 3.8LSAPAMGINIDD3942 pKa = 4.07SLQADD3947 pKa = 4.06TGLSASDD3954 pKa = 4.92FITSVSPVVVNGSLTAALASNEE3976 pKa = 4.05TAQISIDD3983 pKa = 4.41GGTTWTTLTVTGTTWRR3999 pKa = 11.84YY4000 pKa = 9.08NDD4002 pKa = 3.61SRR4004 pKa = 11.84TLTDD4008 pKa = 3.89GNYY4011 pKa = 9.54LYY4013 pKa = 10.1QVRR4016 pKa = 11.84VIDD4019 pKa = 3.57AAGNVGATDD4028 pKa = 3.64SQNVVIDD4035 pKa = 3.67TTAPDD4040 pKa = 3.93PAVKK4044 pKa = 9.61TIAISAITTDD4054 pKa = 3.57MGLITNDD4061 pKa = 3.33FVTSDD4066 pKa = 3.22TTLAVSGTLGATLSAGEE4083 pKa = 4.1FAQISLDD4090 pKa = 4.3GGVTWTTLTVVGTSWSYY4107 pKa = 12.16ADD4109 pKa = 3.83GHH4111 pKa = 5.91TLTDD4115 pKa = 3.66GTWNYY4120 pKa = 7.18TVRR4123 pKa = 11.84VVDD4126 pKa = 3.77LAGNVGQTATQNVVVDD4142 pKa = 4.14TTSPEE4147 pKa = 3.75AAKK4150 pKa = 10.61SITITGISDD4159 pKa = 3.47DD4160 pKa = 4.33TGTSSSDD4167 pKa = 3.5FITSDD4172 pKa = 2.79TTLTVRR4178 pKa = 11.84GVLGAALGANEE4189 pKa = 4.51FAQISTDD4196 pKa = 4.86NGATWVNVTVAADD4209 pKa = 3.63SLNWSYY4215 pKa = 11.97VDD4217 pKa = 5.47GRR4219 pKa = 11.84TLTNGTTTWQVRR4231 pKa = 11.84VVDD4234 pKa = 3.97LAGNVGATSSQSALIDD4250 pKa = 3.72TVNPAQVLTIASISTDD4266 pKa = 3.35TGSSATDD4273 pKa = 4.53FITSDD4278 pKa = 3.17TMLTLTGSLGAGLASGEE4295 pKa = 4.25VAQISLDD4302 pKa = 3.91SGATWTTLTTNGTQWTYY4319 pKa = 10.29TDD4321 pKa = 4.07SRR4323 pKa = 11.84TLTDD4327 pKa = 3.56GSYY4330 pKa = 9.49VYY4332 pKa = 9.26QVRR4335 pKa = 11.84VLDD4338 pKa = 3.99LAGNTGPVVSKK4349 pKa = 9.34TVVVDD4354 pKa = 4.5TINPTATPTIVSYY4367 pKa = 10.98TDD4369 pKa = 4.7DD4370 pKa = 3.3VGQRR4374 pKa = 11.84QGTLSSSQATDD4385 pKa = 3.09DD4386 pKa = 3.81TTPLLNGVLSAPLASGEE4403 pKa = 4.19VVYY4406 pKa = 10.08LYY4408 pKa = 10.98RR4409 pKa = 11.84NGLLLGAVTMVGALNWTYY4427 pKa = 11.25SDD4429 pKa = 3.68SGLVSGAYY4437 pKa = 8.26TYY4439 pKa = 10.34SARR4442 pKa = 11.84VVDD4445 pKa = 4.25LAGNITSSSDD4455 pKa = 3.26FVLTVDD4461 pKa = 3.64TSIPTTLAQITSQTTRR4477 pKa = 11.84DD4478 pKa = 3.54TTPIISGVITAALASGQYY4496 pKa = 9.97VEE4498 pKa = 5.26VVINGKK4504 pKa = 7.97TYY4506 pKa = 9.11TSEE4509 pKa = 3.92PGGAVVVDD4517 pKa = 4.5PAHH4520 pKa = 5.37NTWYY4524 pKa = 10.6VQLPDD4529 pKa = 3.5TDD4531 pKa = 4.29ALTVSATAYY4540 pKa = 8.73TVTAQVKK4547 pKa = 9.99SSAGNGNNANISNGTVTVNAAIDD4570 pKa = 3.9YY4571 pKa = 7.39TPTWTTASKK4580 pKa = 6.89TTAWGLTYY4588 pKa = 10.93GLDD4591 pKa = 3.58SHH4593 pKa = 6.98GMWTVLANQQVMQSTDD4609 pKa = 3.14PLTWSKK4615 pKa = 9.1TALTLYY4621 pKa = 10.65QSGNNYY4627 pKa = 7.66ATSSIADD4634 pKa = 3.54YY4635 pKa = 11.07DD4636 pKa = 4.26RR4637 pKa = 11.84NGTGDD4642 pKa = 3.91LFITRR4647 pKa = 11.84DD4648 pKa = 3.78DD4649 pKa = 4.0YY4650 pKa = 11.25GTGYY4654 pKa = 10.59INGFTNNGDD4663 pKa = 3.72GTFSSAIQVTVGTLTWYY4680 pKa = 10.71GSIVAFDD4687 pKa = 4.13KK4688 pKa = 11.49EE4689 pKa = 4.23GDD4691 pKa = 3.67GYY4693 pKa = 11.41LDD4695 pKa = 3.48FWIGDD4700 pKa = 3.47AGGPDD4705 pKa = 3.81SNTFLWNNAGTLVGNSTTSNSGGSATVGGAVTGYY4739 pKa = 10.93LSLNEE4744 pKa = 4.04GSGVDD4749 pKa = 3.93LNNDD4753 pKa = 2.79GRR4755 pKa = 11.84IDD4757 pKa = 4.34LVQHH4761 pKa = 6.43TYY4763 pKa = 11.15NLNNYY4768 pKa = 7.37YY4769 pKa = 9.35TLSSLINQGNGTFVWGQNTTNTFLSGAGSGAMSSSVSMTWADD4811 pKa = 3.44FDD4813 pKa = 5.13GDD4815 pKa = 3.43GDD4817 pKa = 3.81MDD4819 pKa = 4.6LFLPASQGRR4828 pKa = 11.84ANYY4831 pKa = 10.24GSLLFNTNGVLGCPVAVGATATTYY4855 pKa = 11.24ASQFSLAVDD4864 pKa = 3.85WNHH4867 pKa = 7.32DD4868 pKa = 3.25GLMDD4872 pKa = 3.98IARR4875 pKa = 11.84IAQTGQSYY4883 pKa = 10.48LYY4885 pKa = 9.6TNVSNASNWTQSALGGSQSGTTSGVAAMDD4914 pKa = 4.1YY4915 pKa = 10.77DD4916 pKa = 3.31WDD4918 pKa = 4.04GAVDD4922 pKa = 3.76VLVSKK4927 pKa = 10.93QSGSVFLSRR4936 pKa = 11.84NTNTVSYY4943 pKa = 8.17GTSLHH4948 pKa = 6.9LRR4950 pKa = 11.84ITDD4953 pKa = 3.67PNGINVYY4960 pKa = 10.12YY4961 pKa = 10.76GNTVKK4966 pKa = 10.68LYY4968 pKa = 9.76NSAGVLVATQIINPQSGMGVNDD4990 pKa = 3.8TSALVNFYY4998 pKa = 10.82GLNAGEE5004 pKa = 4.58TYY5006 pKa = 10.75NAVLIKK5012 pKa = 10.21STGTTASNIDD5022 pKa = 3.44QTVNTSWGGLQATDD5036 pKa = 3.18ATHH5039 pKa = 7.35AYY5041 pKa = 9.88DD5042 pKa = 4.68LSAEE5046 pKa = 4.42AGTASNNGKK5055 pKa = 9.69FVGTGYY5061 pKa = 10.92NDD5063 pKa = 3.4TFFATAGTDD5072 pKa = 3.25TYY5074 pKa = 10.75DD5075 pKa = 3.77GSGGWVYY5082 pKa = 11.38SSGTGTWLANGGMDD5096 pKa = 3.6VVDD5099 pKa = 5.1FRR5101 pKa = 11.84LSTVGVTANLSSTAAQATGFNTSTFTNIEE5130 pKa = 4.43GISGSNFNDD5139 pKa = 3.01ILTGSSGDD5147 pKa = 3.54NQLEE5151 pKa = 4.16GRR5153 pKa = 11.84GGNDD5157 pKa = 3.07TLNIGNGGHH5166 pKa = 6.71DD5167 pKa = 3.51TLLYY5171 pKa = 10.7KK5172 pKa = 10.81LLNASDD5178 pKa = 3.69ATGGNGSDD5186 pKa = 3.46VVNGFTVGTWEE5197 pKa = 4.2GTADD5201 pKa = 3.62TDD5203 pKa = 4.8RR5204 pKa = 11.84IDD5206 pKa = 4.52IRR5208 pKa = 11.84EE5209 pKa = 4.08LLQGSGYY5216 pKa = 8.74TGNGKK5221 pKa = 9.95ASYY5224 pKa = 9.92VNGVATLDD5232 pKa = 3.62AQAGNIGDD5240 pKa = 4.09FVKK5243 pKa = 9.69VTQSGSDD5250 pKa = 3.44TIVQIDD5256 pKa = 3.56RR5257 pKa = 11.84DD5258 pKa = 4.11GTGGTFATTNVVTLTGVHH5276 pKa = 6.37TDD5278 pKa = 3.89LATLLANHH5286 pKa = 6.15QLMVVV5291 pKa = 3.73
Molecular weight: 525.83 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>sp|P0A7Z2|RPIA_ECO57 Ribose-5-phosphate isomerase A OS=Escherichia coli O157:H7 OX=83334 GN=rpiA PE=3 SV=1
MM1 pKa = 7.45KK2 pKa = 9.51RR3 pKa = 11.84TFQPSVLKK11 pKa = 10.6RR12 pKa = 11.84NRR14 pKa = 11.84SHH16 pKa = 7.16GFRR19 pKa = 11.84ARR21 pKa = 11.84MATKK25 pKa = 10.4NGRR28 pKa = 11.84QVLARR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84AKK37 pKa = 10.22GRR39 pKa = 11.84ARR41 pKa = 11.84LTVSKK46 pKa = 10.99
MM1 pKa = 7.45KK2 pKa = 9.51RR3 pKa = 11.84TFQPSVLKK11 pKa = 10.6RR12 pKa = 11.84NRR14 pKa = 11.84SHH16 pKa = 7.16GFRR19 pKa = 11.84ARR21 pKa = 11.84MATKK25 pKa = 10.4NGRR28 pKa = 11.84QVLARR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84AKK37 pKa = 10.22GRR39 pKa = 11.84ARR41 pKa = 11.84LTVSKK46 pKa = 10.99
Molecular weight: 5.38 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
 |
|---|
| ChTry ESI |
|
|---|
| ArgC ESI |
|
|---|
| LysN ESI |
|
|---|
| TryLysC ESI |
|
|---|
| Try MALDI |
|
|---|
| ChTry MALDI |
|
|---|
| ArgC MALDI |
|
|---|
| LysN MALDI |
|
|---|
| TryLysC MALDI |
|
|---|
| Try LTQ |
|
|---|
| ChTry LTQ |
|
|---|
| ArgC LTQ |
|
|---|
| LysN LTQ |
|
|---|
| TryLysC LTQ |
|
|---|
| Try MSlow |
|
|---|
| ChTry MSlow |
|
|---|
| ArgC MSlow |
|
|---|
| LysN MSlow |
|
|---|
| TryLysC MSlow |
|
|---|
| Try MShigh |
|
|---|
| ChTry MShigh |
|
|---|
| ArgC MShigh |
|
|---|
| LysN MShigh |
|
|---|
| TryLysC MShigh |
|
|---|
General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
1561664 |
14 |
5291 |
308.4 |
34.17 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
9.432 ± 0.048 | 1.147 ± 0.016 |
5.241 ± 0.03 | 5.856 ± 0.039 |
3.794 ± 0.029 | 7.339 ± 0.035 |
2.21 ± 0.018 | 5.908 ± 0.036 |
4.511 ± 0.033 | 10.396 ± 0.05 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
2.747 ± 0.021 | 4.076 ± 0.033 |
4.386 ± 0.024 | 4.449 ± 0.028 |
5.584 ± 0.035 | 6.004 ± 0.033 |
5.514 ± 0.044 | 6.999 ± 0.033 |
1.525 ± 0.016 | 2.881 ± 0.022 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |