Amino acid dipepetide frequency for Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus) (Crinipellis roreri)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.782AlaAla: 6.782 ± 0.041	0.967AlaCys: 0.967 ± 0.011	3.584AlaAsp: 3.584 ± 0.024	4.449AlaGlu: 4.449 ± 0.029	3.2AlaPhe: 3.2 ± 0.023	4.804AlaGly: 4.804 ± 0.029	1.725AlaHis: 1.725 ± 0.016	4.176AlaIle: 4.176 ± 0.027	3.703AlaLys: 3.703 ± 0.028	7.598AlaLeu: 7.598 ± 0.039	1.768AlaMet: 1.768 ± 0.015	2.749AlaAsn: 2.749 ± 0.019	4.217AlaPro: 4.217 ± 0.035	3.016AlaGln: 3.016 ± 0.02	4.241AlaArg: 4.241 ± 0.026	6.834AlaSer: 6.834 ± 0.039	4.67AlaThr: 4.67 ± 0.029	4.803AlaVal: 4.803 ± 0.029	1.065AlaTrp: 1.065 ± 0.013	2.018AlaTyr: 2.018 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	0.89CysAla: 0.89 ± 0.012	0.243CysCys: 0.243 ± 0.007	0.642CysAsp: 0.642 ± 0.01	0.591CysGlu: 0.591 ± 0.011	0.559CysPhe: 0.559 ± 0.008	0.866CysGly: 0.866 ± 0.013	0.36CysHis: 0.36 ± 0.007	0.756CysIle: 0.756 ± 0.013	0.58CysLys: 0.58 ± 0.009	1.314CysLeu: 1.314 ± 0.015	0.259CysMet: 0.259 ± 0.006	0.466CysAsn: 0.466 ± 0.008	0.724CysPro: 0.724 ± 0.012	0.5CysGln: 0.5 ± 0.009	0.739CysArg: 0.739 ± 0.012	1.029CysSer: 1.029 ± 0.013	0.769CysThr: 0.769 ± 0.011	0.794CysVal: 0.794 ± 0.01	0.211CysTrp: 0.211 ± 0.005	0.381CysTyr: 0.381 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.183AspAla: 4.183 ± 0.024	0.643AspCys: 0.643 ± 0.011	4.045AspAsp: 4.045 ± 0.034	4.262AspGlu: 4.262 ± 0.031	2.184AspPhe: 2.184 ± 0.019	3.757AspGly: 3.757 ± 0.024	1.27AspHis: 1.27 ± 0.014	3.3AspIle: 3.3 ± 0.022	2.324AspLys: 2.324 ± 0.019	4.971AspLeu: 4.971 ± 0.033	1.23AspMet: 1.23 ± 0.014	1.903AspAsn: 1.903 ± 0.016	3.381AspPro: 3.381 ± 0.023	1.703AspGln: 1.703 ± 0.016	2.746AspArg: 2.746 ± 0.023	4.253AspSer: 4.253 ± 0.03	3.087AspThr: 3.087 ± 0.02	3.7AspVal: 3.7 ± 0.021	0.949AspTrp: 0.949 ± 0.011	1.524AspTyr: 1.524 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	4.714GluAla: 4.714 ± 0.028	0.674GluCys: 0.674 ± 0.009	4.082GluAsp: 4.082 ± 0.028	5.548GluGlu: 5.548 ± 0.043	2.024GluPhe: 2.024 ± 0.017	3.687GluGly: 3.687 ± 0.022	1.415GluHis: 1.415 ± 0.013	3.05GluIle: 3.05 ± 0.022	3.595GluLys: 3.595 ± 0.027	5.271GluLeu: 5.271 ± 0.035	1.422GluMet: 1.422 ± 0.014	2.162GluAsn: 2.162 ± 0.017	2.667GluPro: 2.667 ± 0.02	2.312GluGln: 2.312 ± 0.018	3.886GluArg: 3.886 ± 0.028	4.172GluSer: 4.172 ± 0.025	3.151GluThr: 3.151 ± 0.022	3.7GluVal: 3.7 ± 0.025	1.044GluTrp: 1.044 ± 0.014	1.755GluTyr: 1.755 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	2.913PheAla: 2.913 ± 0.023	0.593PheCys: 0.593 ± 0.009	2.353PheAsp: 2.353 ± 0.018	2.141PheGlu: 2.141 ± 0.017	1.81PhePhe: 1.81 ± 0.018	2.783PheGly: 2.783 ± 0.027	1.014PheHis: 1.014 ± 0.012	2.203PheIle: 2.203 ± 0.018	1.679PheLys: 1.679 ± 0.016	3.888PheLeu: 3.888 ± 0.024	0.85PheMet: 0.85 ± 0.01	1.623PheAsn: 1.623 ± 0.014	2.086PhePro: 2.086 ± 0.019	1.404PheGln: 1.404 ± 0.013	2.028PheArg: 2.028 ± 0.018	3.304PheSer: 3.304 ± 0.021	2.431PheThr: 2.431 ± 0.016	2.556PheVal: 2.556 ± 0.023	0.686PheTrp: 0.686 ± 0.011	1.131PheTyr: 1.131 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.435GlyAla: 4.435 ± 0.033	0.828GlyCys: 0.828 ± 0.012	3.252GlyAsp: 3.252 ± 0.023	3.3GlyGlu: 3.3 ± 0.022	2.623GlyPhe: 2.623 ± 0.02	5.134GlyGly: 5.134 ± 0.048	1.574GlyHis: 1.574 ± 0.014	3.489GlyIle: 3.489 ± 0.024	3.362GlyLys: 3.362 ± 0.023	5.698GlyLeu: 5.698 ± 0.028	1.46GlyMet: 1.46 ± 0.018	2.435GlyAsn: 2.435 ± 0.021	3.088GlyPro: 3.088 ± 0.025	2.241GlyGln: 2.241 ± 0.021	3.609GlyArg: 3.609 ± 0.024	5.524GlySer: 5.524 ± 0.034	3.857GlyThr: 3.857 ± 0.026	4.143GlyVal: 4.143 ± 0.024	1.113GlyTrp: 1.113 ± 0.013	2.1GlyTyr: 2.1 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.759HisAla: 1.759 ± 0.015	0.345HisCys: 0.345 ± 0.008	1.292HisAsp: 1.292 ± 0.015	1.265HisGlu: 1.265 ± 0.015	1.005HisPhe: 1.005 ± 0.013	1.557HisGly: 1.557 ± 0.015	0.868HisHis: 0.868 ± 0.015	1.429HisIle: 1.429 ± 0.014	0.947HisLys: 0.947 ± 0.013	2.514HisLeu: 2.514 ± 0.021	0.468HisMet: 0.468 ± 0.008	0.941HisAsn: 0.941 ± 0.01	1.924HisPro: 1.924 ± 0.018	0.969HisGln: 0.969 ± 0.013	1.552HisArg: 1.552 ± 0.019	2.158HisSer: 2.158 ± 0.019	1.435HisThr: 1.435 ± 0.016	1.557HisVal: 1.557 ± 0.015	0.356HisTrp: 0.356 ± 0.007	0.727HisTyr: 0.727 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.072IleAla: 4.072 ± 0.029	0.784IleCys: 0.784 ± 0.011	2.939IleAsp: 2.939 ± 0.022	2.908IleGlu: 2.908 ± 0.02	2.16IlePhe: 2.16 ± 0.02	3.169IleGly: 3.169 ± 0.027	1.445IleHis: 1.445 ± 0.015	2.913IleIle: 2.913 ± 0.025	2.317IleLys: 2.317 ± 0.017	5.102IleLeu: 5.102 ± 0.033	1.053IleMet: 1.053 ± 0.012	1.924IleAsn: 1.924 ± 0.019	3.608IlePro: 3.608 ± 0.021	2.035IleGln: 2.035 ± 0.017	2.993IleArg: 2.993 ± 0.023	4.396IleSer: 4.396 ± 0.025	3.166IleThr: 3.166 ± 0.021	3.432IleVal: 3.432 ± 0.026	0.807IleTrp: 0.807 ± 0.011	1.558IleTyr: 1.558 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.008LysAla: 4.008 ± 0.032	0.578LysCys: 0.578 ± 0.01	2.831LysAsp: 2.831 ± 0.018	3.687LysGlu: 3.687 ± 0.03	1.555LysPhe: 1.555 ± 0.016	3.099LysGly: 3.099 ± 0.024	1.164LysHis: 1.164 ± 0.014	2.285LysIle: 2.285 ± 0.02	3.46LysLys: 3.46 ± 0.036	4.323LysLeu: 4.323 ± 0.029	1.034LysMet: 1.034 ± 0.012	1.785LysAsn: 1.785 ± 0.015	2.714LysPro: 2.714 ± 0.023	1.805LysGln: 1.805 ± 0.015	3.345LysArg: 3.345 ± 0.029	3.477LysSer: 3.477 ± 0.024	2.676LysThr: 2.676 ± 0.022	2.864LysVal: 2.864 ± 0.02	0.768LysTrp: 0.768 ± 0.011	1.357LysTyr: 1.357 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.245LeuAla: 7.245 ± 0.037	1.305LeuCys: 1.305 ± 0.016	5.209LeuAsp: 5.209 ± 0.031	5.61LeuGlu: 5.61 ± 0.035	3.735LeuPhe: 3.735 ± 0.027	5.473LeuGly: 5.473 ± 0.029	2.5LeuHis: 2.5 ± 0.021	4.413LeuIle: 4.413 ± 0.028	4.572LeuLys: 4.572 ± 0.032	8.971LeuLeu: 8.971 ± 0.051	1.841LeuMet: 1.841 ± 0.015	3.501LeuAsn: 3.501 ± 0.021	6.182LeuPro: 6.182 ± 0.033	3.777LeuGln: 3.777 ± 0.023	5.664LeuArg: 5.664 ± 0.031	8.195LeuSer: 8.195 ± 0.039	5.233LeuThr: 5.233 ± 0.029	5.677LeuVal: 5.677 ± 0.032	1.316LeuTrp: 1.316 ± 0.015	2.602LeuTyr: 2.602 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.803MetAla: 1.803 ± 0.016	0.233MetCys: 0.233 ± 0.006	1.296MetAsp: 1.296 ± 0.015	1.284MetGlu: 1.284 ± 0.014	0.832MetPhe: 0.832 ± 0.01	1.307MetGly: 1.307 ± 0.017	0.503MetHis: 0.503 ± 0.008	1.066MetIle: 1.066 ± 0.012	1.149MetLys: 1.149 ± 0.014	1.897MetLeu: 1.897 ± 0.016	0.568MetMet: 0.568 ± 0.009	0.93MetAsn: 0.93 ± 0.011	1.25MetPro: 1.25 ± 0.012	0.795MetGln: 0.795 ± 0.011	1.112MetArg: 1.112 ± 0.012	2.01MetSer: 2.01 ± 0.016	1.344MetThr: 1.344 ± 0.013	1.275MetVal: 1.275 ± 0.014	0.27MetTrp: 0.27 ± 0.006	0.549MetTyr: 0.549 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.139AsnAla: 3.139 ± 0.023	0.455AsnCys: 0.455 ± 0.007	2.113AsnAsp: 2.113 ± 0.019	2.064AsnGlu: 2.064 ± 0.02	1.413AsnPhe: 1.413 ± 0.016	2.741AsnGly: 2.741 ± 0.023	0.941AsnHis: 0.941 ± 0.013	2.185AsnIle: 2.185 ± 0.02	1.531AsnLys: 1.531 ± 0.015	3.467AsnLeu: 3.467 ± 0.021	0.793AsnMet: 0.793 ± 0.012	1.638AsnAsn: 1.638 ± 0.018	2.551AsnPro: 2.551 ± 0.019	1.379AsnGln: 1.379 ± 0.015	1.934AsnArg: 1.934 ± 0.017	3.037AsnSer: 3.037 ± 0.021	2.431AsnThr: 2.431 ± 0.02	2.582AsnVal: 2.582 ± 0.019	0.558AsnTrp: 0.558 ± 0.009	1.037AsnTyr: 1.037 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.5ProAla: 4.5 ± 0.031	0.585ProCys: 0.585 ± 0.011	3.192ProAsp: 3.192 ± 0.023	3.797ProGlu: 3.797 ± 0.023	2.386ProPhe: 2.386 ± 0.021	3.587ProGly: 3.587 ± 0.03	1.477ProHis: 1.477 ± 0.015	2.966ProIle: 2.966 ± 0.018	2.734ProLys: 2.734 ± 0.02	5.194ProLeu: 5.194 ± 0.027	1.088ProMet: 1.088 ± 0.012	2.44ProAsn: 2.44 ± 0.02	5.932ProPro: 5.932 ± 0.065	2.423ProGln: 2.423 ± 0.023	3.265ProArg: 3.265 ± 0.026	6.829ProSer: 6.829 ± 0.046	4.368ProThr: 4.368 ± 0.031	3.683ProVal: 3.683 ± 0.025	0.724ProTrp: 0.724 ± 0.01	1.596ProTyr: 1.596 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.047GlnAla: 3.047 ± 0.023	0.509GlnCys: 0.509 ± 0.009	1.942GlnAsp: 1.942 ± 0.017	2.255GlnGlu: 2.255 ± 0.018	1.366GlnPhe: 1.366 ± 0.013	2.109GlnGly: 2.109 ± 0.021	1.042GlnHis: 1.042 ± 0.013	1.942GlnIle: 1.942 ± 0.018	1.876GlnLys: 1.876 ± 0.016	3.426GlnLeu: 3.426 ± 0.023	0.874GlnMet: 0.874 ± 0.011	1.5GlnAsn: 1.5 ± 0.015	2.307GlnPro: 2.307 ± 0.021	1.995GlnGln: 1.995 ± 0.03	2.394GlnArg: 2.394 ± 0.018	3.08GlnSer: 3.08 ± 0.025	2.338GlnThr: 2.338 ± 0.021	2.249GlnVal: 2.249 ± 0.018	0.612GlnTrp: 0.612 ± 0.01	1.145GlnTyr: 1.145 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.192ArgAla: 4.192 ± 0.023	0.769ArgCys: 0.769 ± 0.011	3.06ArgAsp: 3.06 ± 0.022	3.603ArgGlu: 3.603 ± 0.032	2.269ArgPhe: 2.269 ± 0.019	3.299ArgGly: 3.299 ± 0.023	1.496ArgHis: 1.496 ± 0.015	3.072ArgIle: 3.072 ± 0.02	3.337ArgLys: 3.337 ± 0.024	5.319ArgLeu: 5.319 ± 0.03	1.31ArgMet: 1.31 ± 0.014	2.25ArgAsn: 2.25 ± 0.02	3.31ArgPro: 3.31 ± 0.025	2.214ArgGln: 2.214 ± 0.018	4.646ArgArg: 4.646 ± 0.039	4.85ArgSer: 4.85 ± 0.037	3.319ArgThr: 3.319 ± 0.023	3.362ArgVal: 3.362 ± 0.023	0.958ArgTrp: 0.958 ± 0.011	1.643ArgTyr: 1.643 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.28SerAla: 6.28 ± 0.036	0.951SerCys: 0.951 ± 0.013	4.454SerAsp: 4.454 ± 0.026	4.293SerGlu: 4.293 ± 0.022	3.472SerPhe: 3.472 ± 0.022	5.525SerGly: 5.525 ± 0.035	2.11SerHis: 2.11 ± 0.018	4.352SerIle: 4.352 ± 0.027	3.7SerLys: 3.7 ± 0.031	7.998SerLeu: 7.998 ± 0.04	1.794SerMet: 1.794 ± 0.017	3.264SerAsn: 3.264 ± 0.022	6.148SerPro: 6.148 ± 0.048	3.313SerGln: 3.313 ± 0.026	5.034SerArg: 5.034 ± 0.037	10.318SerSer: 10.318 ± 0.062	6.219SerThr: 6.219 ± 0.038	4.966SerVal: 4.966 ± 0.029	1.179SerTrp: 1.179 ± 0.013	2.165SerTyr: 2.165 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	4.587ThrAla: 4.587 ± 0.025	0.757ThrCys: 0.757 ± 0.011	2.795ThrAsp: 2.795 ± 0.02	3.03ThrGlu: 3.03 ± 0.023	2.527ThrPhe: 2.527 ± 0.018	3.82ThrGly: 3.82 ± 0.028	1.43ThrHis: 1.43 ± 0.015	3.449ThrIle: 3.449 ± 0.024	2.629ThrLys: 2.629 ± 0.021	5.832ThrLeu: 5.832 ± 0.035	1.249ThrMet: 1.249 ± 0.013	2.205ThrAsn: 2.205 ± 0.016	4.574ThrPro: 4.574 ± 0.035	2.131ThrGln: 2.131 ± 0.016	3.269ThrArg: 3.269 ± 0.022	6.004ThrSer: 6.004 ± 0.037	4.376ThrThr: 4.376 ± 0.034	3.941ThrVal: 3.941 ± 0.026	0.857ThrTrp: 0.857 ± 0.011	1.677ThrTyr: 1.677 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	4.787ValAla: 4.787 ± 0.027	0.813ValCys: 0.813 ± 0.01	3.668ValAsp: 3.668 ± 0.022	3.853ValGlu: 3.853 ± 0.025	2.574ValPhe: 2.574 ± 0.019	3.74ValGly: 3.74 ± 0.025	1.546ValHis: 1.546 ± 0.015	3.363ValIle: 3.363 ± 0.026	3.097ValLys: 3.097 ± 0.024	6.018ValLeu: 6.018 ± 0.035	1.372ValMet: 1.372 ± 0.013	2.371ValAsn: 2.371 ± 0.02	3.782ValPro: 3.782 ± 0.025	2.39ValGln: 2.39 ± 0.02	3.169ValArg: 3.169 ± 0.026	4.732ValSer: 4.732 ± 0.029	3.648ValThr: 3.648 ± 0.025	4.44ValVal: 4.44 ± 0.031	0.927ValTrp: 0.927 ± 0.012	1.919ValTyr: 1.919 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.041TrpAla: 1.041 ± 0.012	0.231TrpCys: 0.231 ± 0.006	0.916TrpAsp: 0.916 ± 0.014	0.913TrpGlu: 0.913 ± 0.012	0.594TrpPhe: 0.594 ± 0.01	0.905TrpGly: 0.905 ± 0.012	0.357TrpHis: 0.357 ± 0.007	0.846TrpIle: 0.846 ± 0.01	1.008TrpLys: 1.008 ± 0.012	1.398TrpLeu: 1.398 ± 0.015	0.398TrpMet: 0.398 ± 0.007	0.7TrpAsn: 0.7 ± 0.011	0.615TrpPro: 0.615 ± 0.01	0.528TrpGln: 0.528 ± 0.008	1.012TrpArg: 1.012 ± 0.011	1.167TrpSer: 1.167 ± 0.012	0.915TrpThr: 0.915 ± 0.013	0.855TrpVal: 0.855 ± 0.011	0.314TrpTrp: 0.314 ± 0.007	0.439TrpTyr: 0.439 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.989TyrAla: 1.989 ± 0.017	0.411TyrCys: 0.411 ± 0.008	1.749TyrAsp: 1.749 ± 0.015	1.479TyrGlu: 1.479 ± 0.015	1.189TyrPhe: 1.189 ± 0.013	1.901TyrGly: 1.901 ± 0.019	0.829TyrHis: 0.829 ± 0.011	1.522TyrIle: 1.522 ± 0.015	1.214TyrLys: 1.214 ± 0.015	2.824TyrLeu: 2.824 ± 0.023	0.642TyrMet: 0.642 ± 0.009	1.201TyrAsn: 1.201 ± 0.014	1.709TyrPro: 1.709 ± 0.018	1.078TyrGln: 1.078 ± 0.013	1.644TyrArg: 1.644 ± 0.015	2.167TyrSer: 2.167 ± 0.018	1.706TyrThr: 1.706 ± 0.017	1.63TyrVal: 1.63 ± 0.015	0.437TyrTrp: 0.437 ± 0.008	0.917TyrTyr: 0.917 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 17976 proteins (7359806 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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