Bat circovirus POA/2012/I

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; unclassified Circovirus

Average proteome isoelectric point is 8.01

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0A0YSD4|A0A0A0YSD4_9CIRC Capsid OS=Bat circovirus POA/2012/I OX=1572236 GN=Cap PE=4 SV=1
MM1 pKa = 7.32TLFTKK6 pKa = 10.43VCFTLNNYY14 pKa = 7.57TEE16 pKa = 4.19EE17 pKa = 4.18EE18 pKa = 4.04EE19 pKa = 4.82KK20 pKa = 10.99KK21 pKa = 10.64FLEE24 pKa = 3.97WDD26 pKa = 2.8QWKK29 pKa = 9.98YY30 pKa = 11.05VIIGRR35 pKa = 11.84EE36 pKa = 4.12VGEE39 pKa = 4.35SGTPHH44 pKa = 5.64LQGYY48 pKa = 9.5GEE50 pKa = 4.11LTGRR54 pKa = 11.84KK55 pKa = 9.48RR56 pKa = 11.84MTTLKK61 pKa = 10.7KK62 pKa = 10.44FDD64 pKa = 4.71GKK66 pKa = 10.72AHH68 pKa = 6.56WEE70 pKa = 4.07PLKK73 pKa = 10.17STPEE77 pKa = 3.68AASAYY82 pKa = 9.35CKK84 pKa = 10.22KK85 pKa = 10.52DD86 pKa = 2.97GQFQEE91 pKa = 4.35RR92 pKa = 11.84GVMSSSKK99 pKa = 9.89PVKK102 pKa = 10.31KK103 pKa = 10.31EE104 pKa = 3.45MKK106 pKa = 9.42EE107 pKa = 3.83WIDD110 pKa = 3.49VVKK113 pKa = 10.56NGNMRR118 pKa = 11.84KK119 pKa = 9.62LLDD122 pKa = 3.99SPPNLSTCKK131 pKa = 10.36LMEE134 pKa = 4.1KK135 pKa = 9.49WLTYY139 pKa = 10.23LEE141 pKa = 4.42PVRR144 pKa = 11.84KK145 pKa = 9.35EE146 pKa = 3.91KK147 pKa = 9.38PTVTWLWGASGTGKK161 pKa = 10.61SKK163 pKa = 9.87MAQEE167 pKa = 4.12LAGDD171 pKa = 3.66DD172 pKa = 4.77VYY174 pKa = 11.23WKK176 pKa = 10.61DD177 pKa = 4.26GEE179 pKa = 4.43KK180 pKa = 9.38WWDD183 pKa = 3.58GYY185 pKa = 11.07DD186 pKa = 3.04RR187 pKa = 11.84HH188 pKa = 6.36EE189 pKa = 4.71SVIIDD194 pKa = 4.07DD195 pKa = 4.43FRR197 pKa = 11.84ASNMKK202 pKa = 10.02FNYY205 pKa = 9.92LLRR208 pKa = 11.84LLDD211 pKa = 4.44RR212 pKa = 11.84YY213 pKa = 9.98PMRR216 pKa = 11.84VEE218 pKa = 3.94VKK220 pKa = 10.2GGYY223 pKa = 9.19RR224 pKa = 11.84QMNSKK229 pKa = 10.74NIFITTILYY238 pKa = 8.87PDD240 pKa = 3.8KK241 pKa = 11.0VYY243 pKa = 10.77QLEE246 pKa = 4.45DD247 pKa = 3.7EE248 pKa = 5.17PIKK251 pKa = 10.85QLMRR255 pKa = 11.84RR256 pKa = 11.84IDD258 pKa = 4.66KK259 pKa = 10.56IIEE262 pKa = 4.29CNEE265 pKa = 3.92KK266 pKa = 10.78NLLSQDD272 pKa = 3.96DD273 pKa = 4.3EE274 pKa = 4.51MNEE277 pKa = 3.84

Molecular weight: 32.62 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0A0YSD4|A0A0A0YSD4_9CIRC Capsid OS=Bat circovirus POA/2012/I OX=1572236 GN=Cap PE=4 SV=1
MM1 pKa = 6.57VRR3 pKa = 11.84RR4 pKa = 11.84YY5 pKa = 9.7RR6 pKa = 11.84GPRR9 pKa = 11.84TFIRR13 pKa = 11.84RR14 pKa = 11.84RR15 pKa = 11.84RR16 pKa = 11.84FLRR19 pKa = 11.84KK20 pKa = 8.33SRR22 pKa = 11.84RR23 pKa = 11.84YY24 pKa = 8.87RR25 pKa = 11.84RR26 pKa = 11.84KK27 pKa = 9.61HH28 pKa = 5.46RR29 pKa = 11.84RR30 pKa = 11.84GTNDD34 pKa = 2.46GVRR37 pKa = 11.84YY38 pKa = 9.29FKK40 pKa = 10.67LRR42 pKa = 11.84RR43 pKa = 11.84SIEE46 pKa = 3.83ITDD49 pKa = 3.39VGGGNEE55 pKa = 4.16FTDD58 pKa = 3.97NPSTASDD65 pKa = 3.39WASVSTLFTHH75 pKa = 6.14YY76 pKa = 9.65RR77 pKa = 11.84VKK79 pKa = 10.93AMSIRR84 pKa = 11.84YY85 pKa = 8.68VPRR88 pKa = 11.84FNVNQIASQGSFRR101 pKa = 11.84PLAITHH107 pKa = 6.69DD108 pKa = 4.23VNATTGSLSFNAMIARR124 pKa = 11.84EE125 pKa = 3.99NTRR128 pKa = 11.84ILDD131 pKa = 3.48ASKK134 pKa = 10.43PFTYY138 pKa = 9.38YY139 pKa = 10.62RR140 pKa = 11.84KK141 pKa = 8.82MRR143 pKa = 11.84GIQTQVQTLHH153 pKa = 6.68PGPWYY158 pKa = 9.03RR159 pKa = 11.84TAQPVSTQRR168 pKa = 11.84FFAQTEE174 pKa = 4.11APNTISILGGGVLTLYY190 pKa = 10.2IAAKK194 pKa = 10.58NRR196 pKa = 11.84MM197 pKa = 3.76

Molecular weight: 22.81 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

474

197

277

237.0

27.71

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.641 ± 1.391

0.844 ± 0.476

5.063 ± 1.138

6.329 ± 2.426

4.008 ± 0.889

6.54 ± 0.033

1.477 ± 0.312

5.063 ± 0.58

8.228 ± 2.638

7.173 ± 1.183

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.586 ± 0.592

4.641 ± 0.245

4.219 ± 0.197

3.586 ± 0.268

9.072 ± 3.188

5.907 ± 0.677

7.384 ± 1.276

5.274 ± 0.175

2.532 ± 0.856

4.43 ± 0.078
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski