Amino acid dipepetide frequency for Cucumis melo (Muskmelon)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.019AlaAla: 6.019 ± 0.033	1.21AlaCys: 1.21 ± 0.011	2.977AlaAsp: 2.977 ± 0.017	3.974AlaGlu: 3.974 ± 0.019	2.785AlaPhe: 2.785 ± 0.017	3.84AlaGly: 3.84 ± 0.023	1.267AlaHis: 1.267 ± 0.012	3.941AlaIle: 3.941 ± 0.021	3.733AlaLys: 3.733 ± 0.02	6.531AlaLeu: 6.531 ± 0.029	1.731AlaMet: 1.731 ± 0.013	2.581AlaAsn: 2.581 ± 0.016	2.626AlaPro: 2.626 ± 0.02	1.965AlaGln: 1.965 ± 0.014	3.166AlaArg: 3.166 ± 0.019	5.855AlaSer: 5.855 ± 0.028	3.5AlaThr: 3.5 ± 0.018	4.66AlaVal: 4.66 ± 0.023	0.738AlaTrp: 0.738 ± 0.008	1.747AlaTyr: 1.747 ± 0.013	0.001AlaXaa: 0.001 ± 0.0
Cys	0.955CysAla: 0.955 ± 0.01	0.52CysCys: 0.52 ± 0.008	0.864CysAsp: 0.864 ± 0.01	0.913CysGlu: 0.913 ± 0.01	0.904CysPhe: 0.904 ± 0.01	1.388CysGly: 1.388 ± 0.014	0.46CysHis: 0.46 ± 0.006	1.059CysIle: 1.059 ± 0.011	1.14CysLys: 1.14 ± 0.012	1.86CysLeu: 1.86 ± 0.014	0.421CysMet: 0.421 ± 0.006	0.867CysAsn: 0.867 ± 0.009	0.889CysPro: 0.889 ± 0.012	0.589CysGln: 0.589 ± 0.007	1.046CysArg: 1.046 ± 0.01	1.941CysSer: 1.941 ± 0.015	0.836CysThr: 0.836 ± 0.009	1.02CysVal: 1.02 ± 0.01	0.239CysTrp: 0.239 ± 0.005	0.537CysTyr: 0.537 ± 0.007	0.001CysXaa: 0.001 ± 0.0
Asp	3.364AspAla: 3.364 ± 0.02	0.968AspCys: 0.968 ± 0.01	3.663AspAsp: 3.663 ± 0.024	4.071AspGlu: 4.071 ± 0.021	2.4AspPhe: 2.4 ± 0.015	3.808AspGly: 3.808 ± 0.022	1.283AspHis: 1.283 ± 0.012	3.118AspIle: 3.118 ± 0.017	2.641AspLys: 2.641 ± 0.017	5.11AspLeu: 5.11 ± 0.025	1.272AspMet: 1.272 ± 0.01	2.142AspAsn: 2.142 ± 0.015	2.561AspPro: 2.561 ± 0.015	1.797AspGln: 1.797 ± 0.013	2.469AspArg: 2.469 ± 0.018	4.472AspSer: 4.472 ± 0.024	2.146AspThr: 2.146 ± 0.015	3.63AspVal: 3.63 ± 0.018	0.712AspTrp: 0.712 ± 0.009	1.553AspTyr: 1.553 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	4.665GluAla: 4.665 ± 0.021	0.909GluCys: 0.909 ± 0.01	3.995GluAsp: 3.995 ± 0.021	6.245GluGlu: 6.245 ± 0.04	2.442GluPhe: 2.442 ± 0.016	3.611GluGly: 3.611 ± 0.02	1.248GluHis: 1.248 ± 0.013	3.864GluIle: 3.864 ± 0.018	4.827GluLys: 4.827 ± 0.024	6.002GluLeu: 6.002 ± 0.032	1.812GluMet: 1.812 ± 0.014	3.297GluAsn: 3.297 ± 0.02	2.06GluPro: 2.06 ± 0.015	2.109GluGln: 2.109 ± 0.016	3.456GluArg: 3.456 ± 0.022	4.655GluSer: 4.655 ± 0.023	3.088GluThr: 3.088 ± 0.018	4.196GluVal: 4.196 ± 0.024	0.729GluTrp: 0.729 ± 0.009	1.622GluTyr: 1.622 ± 0.013	0.002GluXaa: 0.002 ± 0.0
Phe	2.432PheAla: 2.432 ± 0.017	0.945PheCys: 0.945 ± 0.009	2.444PheAsp: 2.444 ± 0.015	2.421PheGlu: 2.421 ± 0.016	2.126PhePhe: 2.126 ± 0.02	3.108PheGly: 3.108 ± 0.023	1.189PheHis: 1.189 ± 0.011	2.226PheIle: 2.226 ± 0.016	2.183PheLys: 2.183 ± 0.014	4.538PheLeu: 4.538 ± 0.028	0.923PheMet: 0.923 ± 0.009	1.912PheAsn: 1.912 ± 0.015	2.211PhePro: 2.211 ± 0.015	1.633PheGln: 1.633 ± 0.013	2.125PheArg: 2.125 ± 0.015	4.403PheSer: 4.403 ± 0.02	2.018PheThr: 2.018 ± 0.016	2.809PheVal: 2.809 ± 0.019	0.583PheTrp: 0.583 ± 0.007	1.286PheTyr: 1.286 ± 0.012	0.004PheXaa: 0.004 ± 0.001
Gly	3.653GlyAla: 3.653 ± 0.024	1.307GlyCys: 1.307 ± 0.013	3.333GlyAsp: 3.333 ± 0.016	3.613GlyGlu: 3.613 ± 0.02	3.155GlyPhe: 3.155 ± 0.024	5.194GlyGly: 5.194 ± 0.047	1.502GlyHis: 1.502 ± 0.013	3.703GlyIle: 3.703 ± 0.019	4.054GlyLys: 4.054 ± 0.022	5.804GlyLeu: 5.804 ± 0.026	1.457GlyMet: 1.457 ± 0.013	3.112GlyAsn: 3.112 ± 0.019	2.272GlyPro: 2.272 ± 0.017	1.977GlyGln: 1.977 ± 0.016	3.624GlyArg: 3.624 ± 0.021	5.942GlySer: 5.942 ± 0.027	3.109GlyThr: 3.109 ± 0.017	4.058GlyVal: 4.058 ± 0.02	0.885GlyTrp: 0.885 ± 0.01	2.044GlyTyr: 2.044 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.333HisAla: 1.333 ± 0.012	0.521HisCys: 0.521 ± 0.007	1.162HisAsp: 1.162 ± 0.01	1.292HisGlu: 1.292 ± 0.011	1.144HisPhe: 1.144 ± 0.011	1.712HisGly: 1.712 ± 0.011	1.011HisHis: 1.011 ± 0.015	1.26HisIle: 1.26 ± 0.012	1.2HisLys: 1.2 ± 0.01	2.518HisLeu: 2.518 ± 0.015	0.531HisMet: 0.531 ± 0.007	1.039HisAsn: 1.039 ± 0.01	1.413HisPro: 1.413 ± 0.011	1.057HisGln: 1.057 ± 0.011	1.377HisArg: 1.377 ± 0.012	2.121HisSer: 2.121 ± 0.016	0.969HisThr: 0.969 ± 0.01	1.489HisVal: 1.489 ± 0.011	0.298HisTrp: 0.298 ± 0.005	0.731HisTyr: 0.731 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.619IleAla: 3.619 ± 0.019	1.14IleCys: 1.14 ± 0.011	3.047IleAsp: 3.047 ± 0.019	3.373IleGlu: 3.373 ± 0.019	2.467IlePhe: 2.467 ± 0.017	3.491IleGly: 3.491 ± 0.019	1.388IleHis: 1.388 ± 0.012	2.956IleIle: 2.956 ± 0.017	2.995IleLys: 2.995 ± 0.016	5.562IleLeu: 5.562 ± 0.026	1.153IleMet: 1.153 ± 0.011	2.317IleAsn: 2.317 ± 0.015	3.024IlePro: 3.024 ± 0.02	2.092IleGln: 2.092 ± 0.015	2.712IleArg: 2.712 ± 0.015	5.399IleSer: 5.399 ± 0.024	2.611IleThr: 2.611 ± 0.016	3.563IleVal: 3.563 ± 0.018	0.718IleTrp: 0.718 ± 0.009	1.523IleTyr: 1.523 ± 0.013	0.001IleXaa: 0.001 ± 0.0
Lys	3.946LysAla: 3.946 ± 0.021	0.977LysCys: 0.977 ± 0.011	3.265LysAsp: 3.265 ± 0.019	4.616LysGlu: 4.616 ± 0.026	2.346LysPhe: 2.346 ± 0.015	3.465LysGly: 3.465 ± 0.02	1.353LysHis: 1.353 ± 0.013	3.315LysIle: 3.315 ± 0.019	4.729LysLys: 4.729 ± 0.031	6.099LysLeu: 6.099 ± 0.027	1.542LysMet: 1.542 ± 0.011	2.827LysAsn: 2.827 ± 0.015	2.692LysPro: 2.692 ± 0.017	2.301LysGln: 2.301 ± 0.015	3.621LysArg: 3.621 ± 0.019	4.811LysSer: 4.811 ± 0.029	2.874LysThr: 2.874 ± 0.018	3.843LysVal: 3.843 ± 0.02	0.83LysTrp: 0.83 ± 0.01	1.685LysTyr: 1.685 ± 0.013	0.008LysXaa: 0.008 ± 0.001
Leu	6.34LeuAla: 6.34 ± 0.023	1.864LeuCys: 1.864 ± 0.015	5.099LeuAsp: 5.099 ± 0.024	6.414LeuGlu: 6.414 ± 0.033	4.016LeuPhe: 4.016 ± 0.025	5.684LeuGly: 5.684 ± 0.028	2.722LeuHis: 2.722 ± 0.018	4.855LeuIle: 4.855 ± 0.025	6.339LeuLys: 6.339 ± 0.028	10.152LeuLeu: 10.152 ± 0.043	2.138LeuMet: 2.138 ± 0.015	4.171LeuAsn: 4.171 ± 0.02	5.198LeuPro: 5.198 ± 0.022	4.384LeuGln: 4.384 ± 0.019	5.371LeuArg: 5.371 ± 0.021	8.795LeuSer: 8.795 ± 0.039	4.393LeuThr: 4.393 ± 0.022	6.114LeuVal: 6.114 ± 0.026	1.166LeuTrp: 1.166 ± 0.011	2.522LeuTyr: 2.522 ± 0.017	0.003LeuXaa: 0.003 ± 0.001
Met	2.101MetAla: 2.101 ± 0.016	0.305MetCys: 0.305 ± 0.005	1.437MetAsp: 1.437 ± 0.01	2.04MetGlu: 2.04 ± 0.013	0.854MetPhe: 0.854 ± 0.009	1.592MetGly: 1.592 ± 0.013	0.505MetHis: 0.505 ± 0.006	1.21MetIle: 1.21 ± 0.012	1.699MetLys: 1.699 ± 0.013	2.093MetLeu: 2.093 ± 0.014	0.65MetMet: 0.65 ± 0.009	1.047MetAsn: 1.047 ± 0.01	0.997MetPro: 0.997 ± 0.011	0.876MetGln: 0.876 ± 0.009	1.162MetArg: 1.162 ± 0.011	1.694MetSer: 1.694 ± 0.014	1.024MetThr: 1.024 ± 0.01	1.606MetVal: 1.606 ± 0.012	0.251MetTrp: 0.251 ± 0.005	0.583MetTyr: 0.583 ± 0.009	0.001MetXaa: 0.001 ± 0.0
Asn	2.681AsnAla: 2.681 ± 0.017	0.899AsnCys: 0.899 ± 0.01	2.247AsnAsp: 2.247 ± 0.015	2.733AsnGlu: 2.733 ± 0.017	2.153AsnPhe: 2.153 ± 0.016	3.372AsnGly: 3.372 ± 0.021	1.208AsnHis: 1.208 ± 0.012	2.622AsnIle: 2.622 ± 0.019	2.409AsnLys: 2.409 ± 0.017	4.712AsnLeu: 4.712 ± 0.027	1.056AsnMet: 1.056 ± 0.01	2.57AsnAsn: 2.57 ± 0.023	2.392AsnPro: 2.392 ± 0.016	1.759AsnGln: 1.759 ± 0.013	2.119AsnArg: 2.119 ± 0.014	4.297AsnSer: 4.297 ± 0.02	1.927AsnThr: 1.927 ± 0.014	2.876AsnVal: 2.876 ± 0.018	0.6AsnTrp: 0.6 ± 0.008	1.362AsnTyr: 1.362 ± 0.012	0.001AsnXaa: 0.001 ± 0.0
Pro	2.721ProAla: 2.721 ± 0.02	0.758ProCys: 0.758 ± 0.009	2.409ProAsp: 2.409 ± 0.016	2.954ProGlu: 2.954 ± 0.017	2.106ProPhe: 2.106 ± 0.017	2.507ProGly: 2.507 ± 0.017	1.116ProHis: 1.116 ± 0.011	2.51ProIle: 2.51 ± 0.015	2.73ProLys: 2.73 ± 0.017	4.406ProLeu: 4.406 ± 0.022	0.948ProMet: 0.948 ± 0.01	2.379ProAsn: 2.379 ± 0.016	3.915ProPro: 3.915 ± 0.049	1.773ProGln: 1.773 ± 0.017	2.29ProArg: 2.29 ± 0.017	5.364ProSer: 5.364 ± 0.028	2.685ProThr: 2.685 ± 0.014	2.937ProVal: 2.937 ± 0.017	0.591ProTrp: 0.591 ± 0.008	1.267ProTyr: 1.267 ± 0.012	0.002ProXaa: 0.002 ± 0.001
Gln	2.263GlnAla: 2.263 ± 0.017	0.573GlnCys: 0.573 ± 0.007	1.662GlnAsp: 1.662 ± 0.013	2.324GlnGlu: 2.324 ± 0.017	1.446GlnPhe: 1.446 ± 0.013	1.973GlnGly: 1.973 ± 0.017	0.906GlnHis: 0.906 ± 0.01	2.129GlnIle: 2.129 ± 0.014	2.367GlnLys: 2.367 ± 0.015	3.72GlnLeu: 3.72 ± 0.022	0.979GlnMet: 0.979 ± 0.01	1.851GlnAsn: 1.851 ± 0.013	1.75GlnPro: 1.75 ± 0.014	1.985GlnGln: 1.985 ± 0.028	2.099GlnArg: 2.099 ± 0.015	3.005GlnSer: 3.005 ± 0.018	1.739GlnThr: 1.739 ± 0.015	2.27GlnVal: 2.27 ± 0.015	0.457GlnTrp: 0.457 ± 0.007	0.947GlnTyr: 0.947 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.123ArgAla: 3.123 ± 0.017	0.952ArgCys: 0.952 ± 0.01	2.655ArgAsp: 2.655 ± 0.018	3.339ArgGlu: 3.339 ± 0.02	2.28ArgPhe: 2.28 ± 0.012	3.143ArgGly: 3.143 ± 0.019	1.289ArgHis: 1.289 ± 0.01	2.938ArgIle: 2.938 ± 0.016	3.865ArgLys: 3.865 ± 0.02	5.023ArgLeu: 5.023 ± 0.024	1.311ArgMet: 1.311 ± 0.011	2.568ArgAsn: 2.568 ± 0.015	2.278ArgPro: 2.278 ± 0.016	1.848ArgGln: 1.848 ± 0.013	4.012ArgArg: 4.012 ± 0.028	4.491ArgSer: 4.491 ± 0.027	2.504ArgThr: 2.504 ± 0.014	3.117ArgVal: 3.117 ± 0.018	0.742ArgTrp: 0.742 ± 0.009	1.439ArgTyr: 1.439 ± 0.011	0.002ArgXaa: 0.002 ± 0.0
Ser	5.265SerAla: 5.265 ± 0.026	1.751SerCys: 1.751 ± 0.014	4.575SerAsp: 4.575 ± 0.025	4.959SerGlu: 4.959 ± 0.025	4.232SerPhe: 4.232 ± 0.023	5.808SerGly: 5.808 ± 0.031	2.156SerHis: 2.156 ± 0.014	4.957SerIle: 4.957 ± 0.023	5.187SerLys: 5.187 ± 0.026	8.936SerLeu: 8.936 ± 0.034	2.156SerMet: 2.156 ± 0.014	4.424SerAsn: 4.424 ± 0.023	4.727SerPro: 4.727 ± 0.028	3.156SerGln: 3.156 ± 0.02	4.635SerArg: 4.635 ± 0.026	12.063SerSer: 12.063 ± 0.054	4.964SerThr: 4.964 ± 0.022	5.322SerVal: 5.322 ± 0.02	1.167SerTrp: 1.167 ± 0.012	2.393SerTyr: 2.393 ± 0.016	0.003SerXaa: 0.003 ± 0.001
Thr	3.321ThrAla: 3.321 ± 0.018	0.877ThrCys: 0.877 ± 0.009	2.304ThrAsp: 2.304 ± 0.014	2.745ThrGlu: 2.745 ± 0.015	2.119ThrPhe: 2.119 ± 0.016	3.086ThrGly: 3.086 ± 0.019	1.053ThrHis: 1.053 ± 0.01	2.835ThrIle: 2.835 ± 0.016	2.683ThrLys: 2.683 ± 0.019	4.593ThrLeu: 4.593 ± 0.021	1.146ThrMet: 1.146 ± 0.01	2.212ThrAsn: 2.212 ± 0.013	2.581ThrPro: 2.581 ± 0.017	1.499ThrGln: 1.499 ± 0.013	2.278ThrArg: 2.278 ± 0.014	4.73ThrSer: 4.73 ± 0.022	3.021ThrThr: 3.021 ± 0.02	3.271ThrVal: 3.271 ± 0.018	0.604ThrTrp: 0.604 ± 0.009	1.349ThrTyr: 1.349 ± 0.011	0.001ThrXaa: 0.001 ± 0.0
Val	4.573ValAla: 4.573 ± 0.021	1.111ValCys: 1.111 ± 0.01	3.83ValAsp: 3.83 ± 0.019	4.461ValGlu: 4.461 ± 0.022	2.696ValPhe: 2.696 ± 0.019	4.153ValGly: 4.153 ± 0.021	1.521ValHis: 1.521 ± 0.012	3.402ValIle: 3.402 ± 0.021	3.85ValLys: 3.85 ± 0.021	6.143ValLeu: 6.143 ± 0.028	1.466ValMet: 1.466 ± 0.011	2.624ValAsn: 2.624 ± 0.016	3.057ValPro: 3.057 ± 0.018	2.28ValGln: 2.28 ± 0.015	3.045ValArg: 3.045 ± 0.015	5.44ValSer: 5.44 ± 0.027	3.016ValThr: 3.016 ± 0.018	4.813ValVal: 4.813 ± 0.022	0.74ValTrp: 0.74 ± 0.009	1.865ValTyr: 1.865 ± 0.014	0.002ValXaa: 0.002 ± 0.0
Trp	0.741TrpAla: 0.741 ± 0.008	0.229TrpCys: 0.229 ± 0.004	0.678TrpAsp: 0.678 ± 0.009	0.754TrpGlu: 0.754 ± 0.008	0.553TrpPhe: 0.553 ± 0.007	0.729TrpGly: 0.729 ± 0.009	0.281TrpHis: 0.281 ± 0.005	0.745TrpIle: 0.745 ± 0.01	0.963TrpLys: 0.963 ± 0.011	1.206TrpLeu: 1.206 ± 0.011	0.342TrpMet: 0.342 ± 0.006	0.729TrpAsn: 0.729 ± 0.009	0.5TrpPro: 0.5 ± 0.006	0.424TrpGln: 0.424 ± 0.007	0.83TrpArg: 0.83 ± 0.01	0.997TrpSer: 0.997 ± 0.009	0.642TrpThr: 0.642 ± 0.009	0.767TrpVal: 0.767 ± 0.007	0.236TrpTrp: 0.236 ± 0.005	0.334TrpTyr: 0.334 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.73TyrAla: 1.73 ± 0.014	0.631TyrCys: 0.631 ± 0.007	1.534TyrAsp: 1.534 ± 0.014	1.589TyrGlu: 1.589 ± 0.012	1.29TyrPhe: 1.29 ± 0.012	2.135TyrGly: 2.135 ± 0.017	0.72TyrHis: 0.72 ± 0.009	1.503TyrIle: 1.503 ± 0.012	1.546TyrLys: 1.546 ± 0.013	2.73TyrLeu: 2.73 ± 0.018	0.69TyrMet: 0.69 ± 0.009	1.326TyrAsn: 1.326 ± 0.012	1.223TyrPro: 1.223 ± 0.011	0.943TyrGln: 0.943 ± 0.01	1.482TyrArg: 1.482 ± 0.012	2.361TyrSer: 2.361 ± 0.015	1.241TyrThr: 1.241 ± 0.011	1.726TyrVal: 1.726 ± 0.013	0.39TyrTrp: 0.39 ± 0.006	0.95TyrTyr: 0.95 ± 0.011	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.005XaaPhe: 0.005 ± 0.001	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.008XaaLys: 0.008 ± 0.001	0.003XaaLeu: 0.003 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.012XaaXaa: 0.012 ± 0.003

Statistics based on 25056 proteins (11448345 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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