Amino acid dipepetide frequency for Taibaiella chishuiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.393AlaAla: 9.393 ± 0.11	0.983AlaCys: 0.983 ± 0.024	4.56AlaAsp: 4.56 ± 0.061	4.136AlaGlu: 4.136 ± 0.056	3.868AlaPhe: 3.868 ± 0.056	8.042AlaGly: 8.042 ± 0.097	1.586AlaHis: 1.586 ± 0.034	5.347AlaIle: 5.347 ± 0.063	3.63AlaLys: 3.63 ± 0.061	8.771AlaLeu: 8.771 ± 0.103	2.101AlaMet: 2.101 ± 0.035	3.584AlaAsn: 3.584 ± 0.064	3.491AlaPro: 3.491 ± 0.068	3.714AlaGln: 3.714 ± 0.046	3.76AlaArg: 3.76 ± 0.057	4.746AlaSer: 4.746 ± 0.055	5.651AlaThr: 5.651 ± 0.095	5.478AlaVal: 5.478 ± 0.067	0.974AlaTrp: 0.974 ± 0.026	3.48AlaTyr: 3.48 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.773CysAla: 0.773 ± 0.023	0.228CysCys: 0.228 ± 0.013	0.544CysAsp: 0.544 ± 0.026	0.389CysGlu: 0.389 ± 0.014	0.494CysPhe: 0.494 ± 0.016	0.879CysGly: 0.879 ± 0.024	0.189CysHis: 0.189 ± 0.01	0.738CysIle: 0.738 ± 0.023	0.455CysLys: 0.455 ± 0.018	0.939CysLeu: 0.939 ± 0.026	0.266CysMet: 0.266 ± 0.013	0.559CysAsn: 0.559 ± 0.018	0.488CysPro: 0.488 ± 0.019	0.264CysGln: 0.264 ± 0.016	0.505CysArg: 0.505 ± 0.017	0.781CysSer: 0.781 ± 0.027	0.684CysThr: 0.684 ± 0.024	0.55CysVal: 0.55 ± 0.02	0.125CysTrp: 0.125 ± 0.008	0.42CysTyr: 0.42 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.289AspAla: 4.289 ± 0.052	0.49AspCys: 0.49 ± 0.018	2.404AspAsp: 2.404 ± 0.049	2.863AspGlu: 2.863 ± 0.043	2.703AspPhe: 2.703 ± 0.044	3.73AspGly: 3.73 ± 0.058	1.006AspHis: 1.006 ± 0.027	3.702AspIle: 3.702 ± 0.046	3.365AspLys: 3.365 ± 0.058	4.634AspLeu: 4.634 ± 0.068	1.283AspMet: 1.283 ± 0.026	2.643AspAsn: 2.643 ± 0.04	2.214AspPro: 2.214 ± 0.039	1.811AspGln: 1.811 ± 0.033	2.549AspArg: 2.549 ± 0.043	3.011AspSer: 3.011 ± 0.06	3.361AspThr: 3.361 ± 0.064	2.993AspVal: 2.993 ± 0.04	0.757AspTrp: 0.757 ± 0.023	2.44AspTyr: 2.44 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.822GluAla: 4.822 ± 0.073	0.309GluCys: 0.309 ± 0.014	2.563GluAsp: 2.563 ± 0.052	3.428GluGlu: 3.428 ± 0.059	1.797GluPhe: 1.797 ± 0.037	3.351GluGly: 3.351 ± 0.046	1.286GluHis: 1.286 ± 0.033	3.292GluIle: 3.292 ± 0.046	3.461GluLys: 3.461 ± 0.058	5.372GluLeu: 5.372 ± 0.076	1.315GluMet: 1.315 ± 0.03	2.322GluAsn: 2.322 ± 0.045	1.672GluPro: 1.672 ± 0.029	3.262GluGln: 3.262 ± 0.057	2.722GluArg: 2.722 ± 0.046	2.508GluSer: 2.508 ± 0.041	2.771GluThr: 2.771 ± 0.048	3.221GluVal: 3.221 ± 0.05	0.579GluTrp: 0.579 ± 0.019	1.801GluTyr: 1.801 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.567PheAla: 3.567 ± 0.057	0.523PheCys: 0.523 ± 0.019	2.686PheAsp: 2.686 ± 0.042	2.384PheGlu: 2.384 ± 0.039	2.261PhePhe: 2.261 ± 0.047	3.102PheGly: 3.102 ± 0.044	0.829PheHis: 0.829 ± 0.024	2.937PheIle: 2.937 ± 0.05	2.375PheLys: 2.375 ± 0.04	4.177PheLeu: 4.177 ± 0.061	1.02PheMet: 1.02 ± 0.027	2.522PheAsn: 2.522 ± 0.049	1.843PhePro: 1.843 ± 0.036	1.323PheGln: 1.323 ± 0.031	2.37PheArg: 2.37 ± 0.039	3.424PheSer: 3.424 ± 0.047	3.01PheThr: 3.01 ± 0.047	2.725PheVal: 2.725 ± 0.044	0.534PheTrp: 0.534 ± 0.018	1.979PheTyr: 1.979 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	6.015GlyAla: 6.015 ± 0.085	0.951GlyCys: 0.951 ± 0.035	3.532GlyAsp: 3.532 ± 0.05	2.917GlyGlu: 2.917 ± 0.047	3.457GlyPhe: 3.457 ± 0.054	5.529GlyGly: 5.529 ± 0.101	1.316GlyHis: 1.316 ± 0.028	5.426GlyIle: 5.426 ± 0.063	4.632GlyLys: 4.632 ± 0.063	6.737GlyLeu: 6.737 ± 0.075	1.972GlyMet: 1.972 ± 0.034	4.339GlyAsn: 4.339 ± 0.087	1.965GlyPro: 1.965 ± 0.037	2.742GlyGln: 2.742 ± 0.044	3.282GlyArg: 3.282 ± 0.054	4.887GlySer: 4.887 ± 0.083	5.092GlyThr: 5.092 ± 0.093	4.319GlyVal: 4.319 ± 0.049	0.995GlyTrp: 0.995 ± 0.024	3.196GlyTyr: 3.196 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.472HisAla: 1.472 ± 0.028	0.246HisCys: 0.246 ± 0.013	0.876HisAsp: 0.876 ± 0.024	0.889HisGlu: 0.889 ± 0.026	1.169HisPhe: 1.169 ± 0.026	1.088HisGly: 1.088 ± 0.027	0.54HisHis: 0.54 ± 0.019	1.503HisIle: 1.503 ± 0.032	1.076HisLys: 1.076 ± 0.029	1.877HisLeu: 1.877 ± 0.042	0.436HisMet: 0.436 ± 0.017	0.989HisAsn: 0.989 ± 0.026	1.044HisPro: 1.044 ± 0.024	0.71HisGln: 0.71 ± 0.022	0.897HisArg: 0.897 ± 0.023	1.075HisSer: 1.075 ± 0.023	1.338HisThr: 1.338 ± 0.03	0.98HisVal: 0.98 ± 0.027	0.263HisTrp: 0.263 ± 0.012	1.0HisTyr: 1.0 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.87IleAla: 5.87 ± 0.063	0.775IleCys: 0.775 ± 0.024	3.732IleAsp: 3.732 ± 0.053	3.388IleGlu: 3.388 ± 0.06	2.507IlePhe: 2.507 ± 0.044	4.45IleGly: 4.45 ± 0.059	1.268IleHis: 1.268 ± 0.028	3.735IleIle: 3.735 ± 0.062	3.452IleLys: 3.452 ± 0.057	5.314IleLeu: 5.314 ± 0.065	1.168IleMet: 1.168 ± 0.028	3.305IleAsn: 3.305 ± 0.051	2.999IlePro: 2.999 ± 0.045	2.127IleGln: 2.127 ± 0.038	3.646IleArg: 3.646 ± 0.054	4.189IleSer: 4.189 ± 0.052	4.366IleThr: 4.366 ± 0.057	3.915IleVal: 3.915 ± 0.051	0.629IleTrp: 0.629 ± 0.021	2.338IleTyr: 2.338 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.946LysAla: 4.946 ± 0.072	0.301LysCys: 0.301 ± 0.013	3.362LysAsp: 3.362 ± 0.052	3.841LysGlu: 3.841 ± 0.066	1.738LysPhe: 1.738 ± 0.039	3.874LysGly: 3.874 ± 0.054	1.081LysHis: 1.081 ± 0.025	3.763LysIle: 3.763 ± 0.053	4.117LysLys: 4.117 ± 0.071	4.753LysLeu: 4.753 ± 0.061	1.608LysMet: 1.608 ± 0.029	2.748LysAsn: 2.748 ± 0.042	2.247LysPro: 2.247 ± 0.038	2.496LysGln: 2.496 ± 0.042	2.428LysArg: 2.428 ± 0.04	2.855LysSer: 2.855 ± 0.047	3.447LysThr: 3.447 ± 0.048	3.55LysVal: 3.55 ± 0.046	0.578LysTrp: 0.578 ± 0.02	2.052LysTyr: 2.052 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	7.828LeuAla: 7.828 ± 0.086	1.102LeuCys: 1.102 ± 0.023	4.892LeuAsp: 4.892 ± 0.058	5.067LeuGlu: 5.067 ± 0.073	4.551LeuPhe: 4.551 ± 0.065	5.936LeuGly: 5.936 ± 0.065	2.015LeuHis: 2.015 ± 0.04	5.204LeuIle: 5.204 ± 0.063	5.814LeuLys: 5.814 ± 0.074	10.982LeuLeu: 10.982 ± 0.126	2.202LeuMet: 2.202 ± 0.039	4.671LeuAsn: 4.671 ± 0.064	4.767LeuPro: 4.767 ± 0.062	4.897LeuGln: 4.897 ± 0.062	4.577LeuArg: 4.577 ± 0.061	6.906LeuSer: 6.906 ± 0.07	5.076LeuThr: 5.076 ± 0.061	6.072LeuVal: 6.072 ± 0.058	1.062LeuTrp: 1.062 ± 0.027	3.646LeuTyr: 3.646 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.062MetAla: 2.062 ± 0.036	0.145MetCys: 0.145 ± 0.01	1.247MetAsp: 1.247 ± 0.027	1.325MetGlu: 1.325 ± 0.031	0.776MetPhe: 0.776 ± 0.022	1.499MetGly: 1.499 ± 0.031	0.511MetHis: 0.511 ± 0.016	1.495MetIle: 1.495 ± 0.028	1.833MetLys: 1.833 ± 0.034	2.312MetLeu: 2.312 ± 0.046	0.648MetMet: 0.648 ± 0.019	1.223MetAsn: 1.223 ± 0.026	1.313MetPro: 1.313 ± 0.029	1.237MetGln: 1.237 ± 0.029	1.078MetArg: 1.078 ± 0.027	1.384MetSer: 1.384 ± 0.03	1.248MetThr: 1.248 ± 0.025	1.372MetVal: 1.372 ± 0.029	0.16MetTrp: 0.16 ± 0.01	0.711MetTyr: 0.711 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.139AsnAla: 4.139 ± 0.065	0.548AsnCys: 0.548 ± 0.025	2.4AsnAsp: 2.4 ± 0.047	2.321AsnGlu: 2.321 ± 0.038	2.192AsnPhe: 2.192 ± 0.039	4.156AsnGly: 4.156 ± 0.076	0.785AsnHis: 0.785 ± 0.023	3.479AsnIle: 3.479 ± 0.056	2.716AsnLys: 2.716 ± 0.05	4.275AsnLeu: 4.275 ± 0.065	1.134AsnMet: 1.134 ± 0.025	3.072AsnAsn: 3.072 ± 0.063	2.685AsnPro: 2.685 ± 0.054	1.668AsnGln: 1.668 ± 0.035	2.421AsnArg: 2.421 ± 0.04	2.811AsnSer: 2.811 ± 0.059	3.51AsnThr: 3.51 ± 0.076	2.705AsnVal: 2.705 ± 0.046	0.681AsnTrp: 0.681 ± 0.021	2.214AsnTyr: 2.214 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	4.939ProAla: 4.939 ± 0.073	0.373ProCys: 0.373 ± 0.015	2.756ProAsp: 2.756 ± 0.044	2.985ProGlu: 2.985 ± 0.043	1.984ProPhe: 1.984 ± 0.035	4.147ProGly: 4.147 ± 0.064	0.68ProHis: 0.68 ± 0.02	1.791ProIle: 1.791 ± 0.035	1.645ProLys: 1.645 ± 0.036	3.794ProLeu: 3.794 ± 0.053	0.907ProMet: 0.907 ± 0.024	1.856ProAsn: 1.856 ± 0.043	1.509ProPro: 1.509 ± 0.039	1.598ProGln: 1.598 ± 0.032	1.36ProArg: 1.36 ± 0.028	2.069ProSer: 2.069 ± 0.038	1.917ProThr: 1.917 ± 0.047	4.214ProVal: 4.214 ± 0.061	0.386ProTrp: 0.386 ± 0.015	1.719ProTyr: 1.719 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.573GlnAla: 3.573 ± 0.047	0.291GlnCys: 0.291 ± 0.013	1.981GlnAsp: 1.981 ± 0.035	2.41GlnGlu: 2.41 ± 0.045	1.627GlnPhe: 1.627 ± 0.033	2.499GlnGly: 2.499 ± 0.039	1.061GlnHis: 1.061 ± 0.024	2.103GlnIle: 2.103 ± 0.035	2.296GlnLys: 2.296 ± 0.039	4.543GlnLeu: 4.543 ± 0.056	0.982GlnMet: 0.982 ± 0.026	1.679GlnAsn: 1.679 ± 0.037	2.02GlnPro: 2.02 ± 0.034	3.004GlnGln: 3.004 ± 0.063	1.943GlnArg: 1.943 ± 0.04	2.233GlnSer: 2.233 ± 0.038	2.119GlnThr: 2.119 ± 0.04	2.988GlnVal: 2.988 ± 0.045	0.556GlnTrp: 0.556 ± 0.016	1.854GlnTyr: 1.854 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.964ArgAla: 2.964 ± 0.044	0.371ArgCys: 0.371 ± 0.016	2.354ArgAsp: 2.354 ± 0.036	2.658ArgGlu: 2.658 ± 0.05	2.466ArgPhe: 2.466 ± 0.041	2.305ArgGly: 2.305 ± 0.038	1.003ArgHis: 1.003 ± 0.029	3.579ArgIle: 3.579 ± 0.052	3.245ArgLys: 3.245 ± 0.048	4.743ArgLeu: 4.743 ± 0.06	1.406ArgMet: 1.406 ± 0.027	2.593ArgAsn: 2.593 ± 0.041	1.708ArgPro: 1.708 ± 0.035	2.266ArgGln: 2.266 ± 0.041	2.145ArgArg: 2.145 ± 0.045	2.698ArgSer: 2.698 ± 0.053	2.386ArgThr: 2.386 ± 0.041	2.788ArgVal: 2.788 ± 0.042	0.588ArgTrp: 0.588 ± 0.02	2.338ArgTyr: 2.338 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.933SerAla: 4.933 ± 0.057	0.717SerCys: 0.717 ± 0.019	3.004SerAsp: 3.004 ± 0.043	2.568SerGlu: 2.568 ± 0.044	3.408SerPhe: 3.408 ± 0.051	5.697SerGly: 5.697 ± 0.086	0.945SerHis: 0.945 ± 0.023	3.844SerIle: 3.844 ± 0.047	2.851SerLys: 2.851 ± 0.053	6.257SerLeu: 6.257 ± 0.063	1.363SerMet: 1.363 ± 0.029	2.946SerAsn: 2.946 ± 0.056	2.512SerPro: 2.512 ± 0.044	1.779SerGln: 1.779 ± 0.032	2.812SerArg: 2.812 ± 0.043	3.564SerSer: 3.564 ± 0.061	3.34SerThr: 3.34 ± 0.062	4.027SerVal: 4.027 ± 0.062	0.798SerTrp: 0.798 ± 0.024	2.689SerTyr: 2.689 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	6.195ThrAla: 6.195 ± 0.088	0.594ThrCys: 0.594 ± 0.018	3.403ThrAsp: 3.403 ± 0.048	2.932ThrGlu: 2.932 ± 0.046	2.736ThrPhe: 2.736 ± 0.047	6.096ThrGly: 6.096 ± 0.097	1.01ThrHis: 1.01 ± 0.023	3.894ThrIle: 3.894 ± 0.054	2.208ThrLys: 2.208 ± 0.043	6.141ThrLeu: 6.141 ± 0.068	1.075ThrMet: 1.075 ± 0.025	2.513ThrAsn: 2.513 ± 0.051	3.101ThrPro: 3.101 ± 0.053	1.999ThrGln: 1.999 ± 0.04	2.497ThrArg: 2.497 ± 0.038	3.294ThrSer: 3.294 ± 0.056	4.2ThrThr: 4.2 ± 0.089	4.561ThrVal: 4.561 ± 0.074	0.757ThrTrp: 0.757 ± 0.026	2.599ThrTyr: 2.599 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.493ValAla: 5.493 ± 0.069	0.727ValCys: 0.727 ± 0.023	2.98ValAsp: 2.98 ± 0.043	2.71ValGlu: 2.71 ± 0.045	3.09ValPhe: 3.09 ± 0.05	3.351ValGly: 3.351 ± 0.049	1.214ValHis: 1.214 ± 0.025	4.114ValIle: 4.114 ± 0.061	3.715ValLys: 3.715 ± 0.046	6.45ValLeu: 6.45 ± 0.072	1.529ValMet: 1.529 ± 0.037	3.255ValAsn: 3.255 ± 0.05	2.881ValPro: 2.881 ± 0.046	2.567ValGln: 2.567 ± 0.044	2.702ValArg: 2.702 ± 0.044	4.379ValSer: 4.379 ± 0.049	4.55ValThr: 4.55 ± 0.084	4.253ValVal: 4.253 ± 0.06	0.706ValTrp: 0.706 ± 0.023	2.875ValTyr: 2.875 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.814TrpAla: 0.814 ± 0.023	0.122TrpCys: 0.122 ± 0.008	0.682TrpAsp: 0.682 ± 0.022	0.611TrpGlu: 0.611 ± 0.018	0.536TrpPhe: 0.536 ± 0.019	0.763TrpGly: 0.763 ± 0.023	0.288TrpHis: 0.288 ± 0.013	0.77TrpIle: 0.77 ± 0.021	0.715TrpLys: 0.715 ± 0.024	1.251TrpLeu: 1.251 ± 0.032	0.343TrpMet: 0.343 ± 0.016	0.676TrpAsn: 0.676 ± 0.021	0.316TrpPro: 0.316 ± 0.013	0.694TrpGln: 0.694 ± 0.02	0.511TrpArg: 0.511 ± 0.018	0.707TrpSer: 0.707 ± 0.02	0.71TrpThr: 0.71 ± 0.027	0.675TrpVal: 0.675 ± 0.021	0.176TrpTrp: 0.176 ± 0.01	0.523TrpTyr: 0.523 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.21TyrAla: 3.21 ± 0.05	0.473TyrCys: 0.473 ± 0.018	2.286TyrAsp: 2.286 ± 0.044	2.033TyrGlu: 2.033 ± 0.037	2.233TyrPhe: 2.233 ± 0.034	2.806TyrGly: 2.806 ± 0.052	0.853TyrHis: 0.853 ± 0.019	2.457TyrIle: 2.457 ± 0.035	2.183TyrLys: 2.183 ± 0.043	3.945TyrLeu: 3.945 ± 0.054	0.821TyrMet: 0.821 ± 0.023	2.418TyrAsn: 2.418 ± 0.042	1.855TyrPro: 1.855 ± 0.037	1.606TyrGln: 1.606 ± 0.03	2.397TyrArg: 2.397 ± 0.044	2.534TyrSer: 2.534 ± 0.041	3.029TyrThr: 3.029 ± 0.055	2.155TyrVal: 2.155 ± 0.043	0.58TyrTrp: 0.58 ± 0.016	2.106TyrTyr: 2.106 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4946 proteins (1698191 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---