Human adenovirus D37

Taxonomy: Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus D

Average proteome isoelectric point is 6.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 36 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|B2VQE5|B2VQE5_9ADEN Hexon-interlacing protein OS=Human adenovirus D37 OX=52275 GN=pIX PE=2 SV=1
MM1 pKa = 7.48RR2 pKa = 11.84HH3 pKa = 5.92LRR5 pKa = 11.84LLSSTVPINMAALLLEE21 pKa = 5.34DD22 pKa = 3.96YY23 pKa = 11.04VSTVLEE29 pKa = 4.79DD30 pKa = 3.82EE31 pKa = 4.6LHH33 pKa = 6.57PSPFEE38 pKa = 4.82LGPTLQDD45 pKa = 3.63LYY47 pKa = 11.36DD48 pKa = 4.71LEE50 pKa = 5.3VDD52 pKa = 4.74AHH54 pKa = 7.26DD55 pKa = 5.62DD56 pKa = 3.91DD57 pKa = 5.34PNEE60 pKa = 3.98EE61 pKa = 4.1AVNLIFPEE69 pKa = 4.1SLILQADD76 pKa = 3.89IASEE80 pKa = 4.06AVPTPLHH87 pKa = 6.23TPTLSPIPEE96 pKa = 4.36LEE98 pKa = 4.34EE99 pKa = 4.11EE100 pKa = 4.64DD101 pKa = 4.64EE102 pKa = 4.71LDD104 pKa = 3.55LRR106 pKa = 11.84CYY108 pKa = 10.79EE109 pKa = 4.21EE110 pKa = 5.23GFPPSDD116 pKa = 3.76SEE118 pKa = 5.05DD119 pKa = 3.71EE120 pKa = 4.11QGEE123 pKa = 3.98QSMALISEE131 pKa = 4.56YY132 pKa = 10.4ACVVVEE138 pKa = 3.99EE139 pKa = 5.02HH140 pKa = 6.62FVLDD144 pKa = 3.73NPEE147 pKa = 4.07VPGQGCRR154 pKa = 11.84SCQYY158 pKa = 10.69HH159 pKa = 6.7RR160 pKa = 11.84DD161 pKa = 3.48KK162 pKa = 11.45TGDD165 pKa = 3.55TNASCALCYY174 pKa = 9.23MKK176 pKa = 10.83KK177 pKa = 9.86NFSFIYY183 pKa = 10.29SPVSEE188 pKa = 5.06DD189 pKa = 3.15EE190 pKa = 4.38SSPSEE195 pKa = 4.19EE196 pKa = 4.03NHH198 pKa = 6.28PCPPEE203 pKa = 4.29LSGEE207 pKa = 4.35TPLQVHH213 pKa = 6.61KK214 pKa = 7.82PTPVRR219 pKa = 11.84PSGEE223 pKa = 3.32RR224 pKa = 11.84RR225 pKa = 11.84AAVEE229 pKa = 4.11KK230 pKa = 10.82IEE232 pKa = 5.54DD233 pKa = 4.22LLHH236 pKa = 7.54DD237 pKa = 4.08MGGDD241 pKa = 3.59EE242 pKa = 5.63PLDD245 pKa = 3.88LSLKK249 pKa = 10.14RR250 pKa = 11.84PRR252 pKa = 11.84NN253 pKa = 3.53

Molecular weight: 28.21 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|B2VQF5|B2VQF5_9ADEN Isoform of Q3S8A5 Pre-protein VI OS=Human adenovirus D37 OX=52275 GN=L3 PE=2 SV=1
MM1 pKa = 7.77ALTCRR6 pKa = 11.84LRR8 pKa = 11.84IPVPNYY14 pKa = 8.76RR15 pKa = 11.84GRR17 pKa = 11.84SRR19 pKa = 11.84RR20 pKa = 11.84RR21 pKa = 11.84RR22 pKa = 11.84GMAGSGLNRR31 pKa = 11.84RR32 pKa = 11.84RR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84AMRR38 pKa = 11.84RR39 pKa = 11.84RR40 pKa = 11.84LSGGFLPALIPIIAAAIGTIPGIASVALQASQRR73 pKa = 11.84RR74 pKa = 3.83

Molecular weight: 8.19 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

14

22

36

11222

65

1091

311.7

35.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.129 ± 0.357

1.987 ± 0.294

5.168 ± 0.333

6.363 ± 0.501

3.85 ± 0.251

6.193 ± 0.287

2.62 ± 0.239

3.885 ± 0.217

4.01 ± 0.381

9.562 ± 0.387

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.736 ± 0.24

4.429 ± 0.388

6.648 ± 0.356

4.331 ± 0.257

7.361 ± 0.588

6.505 ± 0.321

5.944 ± 0.464

6.523 ± 0.294

1.39 ± 0.117

3.368 ± 0.257
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski