Amino acid dipepetide frequency for Morchella conica CCBAS932

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.238AlaAla: 9.238 ± 0.083	0.982AlaCys: 0.982 ± 0.019	3.774AlaAsp: 3.774 ± 0.031	5.339AlaGlu: 5.339 ± 0.051	2.766AlaPhe: 2.766 ± 0.026	5.904AlaGly: 5.904 ± 0.039	1.72AlaHis: 1.72 ± 0.017	3.932AlaIle: 3.932 ± 0.033	3.999AlaLys: 3.999 ± 0.035	7.372AlaLeu: 7.372 ± 0.054	1.799AlaMet: 1.799 ± 0.02	2.571AlaAsn: 2.571 ± 0.025	5.012AlaPro: 5.012 ± 0.05	2.904AlaGln: 2.904 ± 0.035	4.667AlaArg: 4.667 ± 0.034	6.449AlaSer: 6.449 ± 0.043	5.081AlaThr: 5.081 ± 0.039	5.446AlaVal: 5.446 ± 0.046	1.02AlaTrp: 1.02 ± 0.017	1.929AlaTyr: 1.929 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.953CysAla: 0.953 ± 0.015	0.284CysCys: 0.284 ± 0.009	0.618CysAsp: 0.618 ± 0.013	0.667CysGlu: 0.667 ± 0.012	0.557CysPhe: 0.557 ± 0.012	1.043CysGly: 1.043 ± 0.019	0.329CysHis: 0.329 ± 0.009	0.685CysIle: 0.685 ± 0.013	0.571CysLys: 0.571 ± 0.012	1.223CysLeu: 1.223 ± 0.018	0.319CysMet: 0.319 ± 0.008	0.451CysAsn: 0.451 ± 0.011	0.649CysPro: 0.649 ± 0.013	0.397CysGln: 0.397 ± 0.01	0.756CysArg: 0.756 ± 0.013	0.934CysSer: 0.934 ± 0.016	0.75CysThr: 0.75 ± 0.014	0.87CysVal: 0.87 ± 0.016	0.194CysTrp: 0.194 ± 0.006	0.376CysTyr: 0.376 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.059AspAla: 4.059 ± 0.029	0.613AspCys: 0.613 ± 0.014	4.06AspAsp: 4.06 ± 0.048	4.504AspGlu: 4.504 ± 0.048	2.016AspPhe: 2.016 ± 0.021	3.911AspGly: 3.911 ± 0.034	1.12AspHis: 1.12 ± 0.017	3.143AspIle: 3.143 ± 0.026	2.347AspLys: 2.347 ± 0.023	4.551AspLeu: 4.551 ± 0.033	1.248AspMet: 1.248 ± 0.018	1.856AspAsn: 1.856 ± 0.024	2.995AspPro: 2.995 ± 0.025	1.531AspGln: 1.531 ± 0.019	2.793AspArg: 2.793 ± 0.029	3.859AspSer: 3.859 ± 0.034	2.882AspThr: 2.882 ± 0.026	3.467AspVal: 3.467 ± 0.027	0.778AspTrp: 0.778 ± 0.015	1.56AspTyr: 1.56 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.322GluAla: 5.322 ± 0.048	0.729GluCys: 0.729 ± 0.013	4.448GluAsp: 4.448 ± 0.046	7.045GluGlu: 7.045 ± 0.081	2.091GluPhe: 2.091 ± 0.02	4.54GluGly: 4.54 ± 0.037	1.301GluHis: 1.301 ± 0.016	3.407GluIle: 3.407 ± 0.029	4.441GluLys: 4.441 ± 0.043	5.375GluLeu: 5.375 ± 0.04	1.698GluMet: 1.698 ± 0.019	2.498GluAsn: 2.498 ± 0.026	2.558GluPro: 2.558 ± 0.026	2.217GluGln: 2.217 ± 0.026	4.527GluArg: 4.527 ± 0.048	4.284GluSer: 4.284 ± 0.04	3.548GluThr: 3.548 ± 0.032	4.102GluVal: 4.102 ± 0.033	0.944GluTrp: 0.944 ± 0.013	1.85GluTyr: 1.85 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	2.667PheAla: 2.667 ± 0.026	0.584PheCys: 0.584 ± 0.012	2.063PheAsp: 2.063 ± 0.022	2.185PheGlu: 2.185 ± 0.021	1.702PhePhe: 1.702 ± 0.027	2.722PheGly: 2.722 ± 0.031	0.854PheHis: 0.854 ± 0.014	1.787PheIle: 1.787 ± 0.025	1.579PheLys: 1.579 ± 0.02	3.473PheLeu: 3.473 ± 0.032	0.787PheMet: 0.787 ± 0.015	1.385PheAsn: 1.385 ± 0.018	1.936PhePro: 1.936 ± 0.02	1.232PheGln: 1.232 ± 0.019	1.925PheArg: 1.925 ± 0.02	3.015PheSer: 3.015 ± 0.028	2.228PheThr: 2.228 ± 0.023	2.321PheVal: 2.321 ± 0.022	0.549PheTrp: 0.549 ± 0.013	1.095PheTyr: 1.095 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.532GlyAla: 5.532 ± 0.045	0.912GlyCys: 0.912 ± 0.017	3.71GlyAsp: 3.71 ± 0.034	4.452GlyGlu: 4.452 ± 0.04	2.755GlyPhe: 2.755 ± 0.024	7.53GlyGly: 7.53 ± 0.08	1.568GlyHis: 1.568 ± 0.024	3.537GlyIle: 3.537 ± 0.031	3.833GlyLys: 3.833 ± 0.028	5.678GlyLeu: 5.678 ± 0.038	1.777GlyMet: 1.777 ± 0.021	2.665GlyAsn: 2.665 ± 0.027	3.047GlyPro: 3.047 ± 0.033	2.128GlyGln: 2.128 ± 0.024	4.491GlyArg: 4.491 ± 0.036	5.71GlySer: 5.71 ± 0.048	4.003GlyThr: 4.003 ± 0.037	4.883GlyVal: 4.883 ± 0.038	1.174GlyTrp: 1.174 ± 0.018	2.163GlyTyr: 2.163 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.657HisAla: 1.657 ± 0.019	0.321HisCys: 0.321 ± 0.008	1.142HisAsp: 1.142 ± 0.015	1.235HisGlu: 1.235 ± 0.017	0.856HisPhe: 0.856 ± 0.015	1.569HisGly: 1.569 ± 0.022	1.016HisHis: 1.016 ± 0.02	1.282HisIle: 1.282 ± 0.018	0.984HisLys: 0.984 ± 0.016	2.25HisLeu: 2.25 ± 0.025	0.471HisMet: 0.471 ± 0.01	0.877HisAsn: 0.877 ± 0.015	1.777HisPro: 1.777 ± 0.026	1.009HisGln: 1.009 ± 0.019	1.519HisArg: 1.519 ± 0.019	1.904HisSer: 1.904 ± 0.023	1.406HisThr: 1.406 ± 0.016	1.287HisVal: 1.287 ± 0.017	0.304HisTrp: 0.304 ± 0.008	0.708HisTyr: 0.708 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.0IleAla: 4.0 ± 0.032	0.758IleCys: 0.758 ± 0.013	2.818IleAsp: 2.818 ± 0.027	3.14IleGlu: 3.14 ± 0.026	1.976IlePhe: 1.976 ± 0.023	3.111IleGly: 3.111 ± 0.029	1.247IleHis: 1.247 ± 0.019	2.674IleIle: 2.674 ± 0.028	2.499IleLys: 2.499 ± 0.026	4.549IleLeu: 4.549 ± 0.035	1.052IleMet: 1.052 ± 0.016	1.955IleAsn: 1.955 ± 0.018	3.176IlePro: 3.176 ± 0.025	1.764IleGln: 1.764 ± 0.019	2.775IleArg: 2.775 ± 0.02	4.09IleSer: 4.09 ± 0.031	3.197IleThr: 3.197 ± 0.029	3.165IleVal: 3.165 ± 0.029	0.657IleTrp: 0.657 ± 0.013	1.448IleTyr: 1.448 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.27LysAla: 4.27 ± 0.041	0.566LysCys: 0.566 ± 0.013	2.854LysAsp: 2.854 ± 0.029	4.131LysGlu: 4.131 ± 0.042	1.509LysPhe: 1.509 ± 0.019	3.343LysGly: 3.343 ± 0.027	1.136LysHis: 1.136 ± 0.017	2.623LysIle: 2.623 ± 0.025	4.237LysLys: 4.237 ± 0.047	4.182LysLeu: 4.182 ± 0.033	1.176LysMet: 1.176 ± 0.017	2.043LysAsn: 2.043 ± 0.02	2.715LysPro: 2.715 ± 0.026	1.745LysGln: 1.745 ± 0.02	3.775LysArg: 3.775 ± 0.033	3.621LysSer: 3.621 ± 0.032	3.07LysThr: 3.07 ± 0.026	3.082LysVal: 3.082 ± 0.024	0.704LysTrp: 0.704 ± 0.013	1.44LysTyr: 1.44 ± 0.017	0.001LysXaa: 0.001 ± 0.0
Leu	6.977LeuAla: 6.977 ± 0.046	1.228LeuCys: 1.228 ± 0.018	4.652LeuAsp: 4.652 ± 0.034	5.838LeuGlu: 5.838 ± 0.044	3.316LeuPhe: 3.316 ± 0.028	5.746LeuGly: 5.746 ± 0.042	2.297LeuHis: 2.297 ± 0.024	3.928LeuIle: 3.928 ± 0.029	4.569LeuLys: 4.569 ± 0.035	8.61LeuLeu: 8.61 ± 0.07	1.806LeuMet: 1.806 ± 0.022	3.037LeuAsn: 3.037 ± 0.026	5.415LeuPro: 5.415 ± 0.038	3.443LeuGln: 3.443 ± 0.032	5.485LeuArg: 5.485 ± 0.043	7.086LeuSer: 7.086 ± 0.04	4.878LeuThr: 4.878 ± 0.038	5.281LeuVal: 5.281 ± 0.045	1.148LeuTrp: 1.148 ± 0.022	2.355LeuTyr: 2.355 ± 0.025	0.001LeuXaa: 0.001 ± 0.0
Met	2.018MetAla: 2.018 ± 0.02	0.264MetCys: 0.264 ± 0.008	1.256MetAsp: 1.256 ± 0.016	1.51MetGlu: 1.51 ± 0.019	0.808MetPhe: 0.808 ± 0.014	1.632MetGly: 1.632 ± 0.022	0.464MetHis: 0.464 ± 0.01	1.038MetIle: 1.038 ± 0.016	1.158MetLys: 1.158 ± 0.016	1.82MetLeu: 1.82 ± 0.02	0.618MetMet: 0.618 ± 0.011	0.853MetAsn: 0.853 ± 0.017	1.198MetPro: 1.198 ± 0.018	0.78MetGln: 0.78 ± 0.016	1.325MetArg: 1.325 ± 0.019	1.921MetSer: 1.921 ± 0.024	1.245MetThr: 1.245 ± 0.016	1.419MetVal: 1.419 ± 0.018	0.295MetTrp: 0.295 ± 0.008	0.553MetTyr: 0.553 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.789AsnAla: 2.789 ± 0.027	0.465AsnCys: 0.465 ± 0.013	1.891AsnAsp: 1.891 ± 0.02	2.071AsnGlu: 2.071 ± 0.023	1.35AsnPhe: 1.35 ± 0.019	2.876AsnGly: 2.876 ± 0.031	0.913AsnHis: 0.913 ± 0.015	2.189AsnIle: 2.189 ± 0.02	1.69AsnLys: 1.69 ± 0.02	3.169AsnLeu: 3.169 ± 0.028	0.847AsnMet: 0.847 ± 0.014	1.7AsnAsn: 1.7 ± 0.025	2.498AsnPro: 2.498 ± 0.024	1.26AsnGln: 1.26 ± 0.019	2.015AsnArg: 2.015 ± 0.023	3.044AsnSer: 3.044 ± 0.03	2.452AsnThr: 2.452 ± 0.027	2.224AsnVal: 2.224 ± 0.024	0.515AsnTrp: 0.515 ± 0.01	1.097AsnTyr: 1.097 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	5.268ProAla: 5.268 ± 0.046	0.494ProCys: 0.494 ± 0.013	2.743ProAsp: 2.743 ± 0.024	3.781ProGlu: 3.781 ± 0.034	1.879ProPhe: 1.879 ± 0.02	3.831ProGly: 3.831 ± 0.038	1.498ProHis: 1.498 ± 0.021	2.702ProIle: 2.702 ± 0.031	2.807ProLys: 2.807 ± 0.031	4.823ProLeu: 4.823 ± 0.04	1.079ProMet: 1.079 ± 0.015	2.137ProAsn: 2.137 ± 0.024	6.481ProPro: 6.481 ± 0.086	2.446ProGln: 2.446 ± 0.037	3.359ProArg: 3.359 ± 0.029	5.727ProSer: 5.727 ± 0.048	4.549ProThr: 4.549 ± 0.038	3.6ProVal: 3.6 ± 0.031	0.622ProTrp: 0.622 ± 0.012	1.462ProTyr: 1.462 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	2.852GlnAla: 2.852 ± 0.032	0.405GlnCys: 0.405 ± 0.01	1.657GlnAsp: 1.657 ± 0.021	2.286GlnGlu: 2.286 ± 0.024	1.156GlnPhe: 1.156 ± 0.016	2.102GlnGly: 2.102 ± 0.024	1.004GlnHis: 1.004 ± 0.019	1.755GlnIle: 1.755 ± 0.018	2.007GlnLys: 2.007 ± 0.022	3.13GlnLeu: 3.13 ± 0.029	0.831GlnMet: 0.831 ± 0.014	1.497GlnAsn: 1.497 ± 0.02	2.138GlnPro: 2.138 ± 0.035	2.947GlnGln: 2.947 ± 0.113	2.448GlnArg: 2.448 ± 0.024	2.654GlnSer: 2.654 ± 0.03	2.036GlnThr: 2.036 ± 0.02	1.922GlnVal: 1.922 ± 0.024	0.467GlnTrp: 0.467 ± 0.011	1.059GlnTyr: 1.059 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.62ArgAla: 4.62 ± 0.038	0.789ArgCys: 0.789 ± 0.016	3.142ArgAsp: 3.142 ± 0.031	4.261ArgGlu: 4.261 ± 0.037	2.141ArgPhe: 2.141 ± 0.022	4.309ArgGly: 4.309 ± 0.038	1.416ArgHis: 1.416 ± 0.018	3.023ArgIle: 3.023 ± 0.026	3.784ArgLys: 3.784 ± 0.033	5.157ArgLeu: 5.157 ± 0.035	1.428ArgMet: 1.428 ± 0.017	2.363ArgAsn: 2.363 ± 0.022	3.279ArgPro: 3.279 ± 0.034	2.236ArgGln: 2.236 ± 0.024	5.295ArgArg: 5.295 ± 0.056	4.642ArgSer: 4.642 ± 0.041	3.325ArgThr: 3.325 ± 0.025	3.599ArgVal: 3.599 ± 0.027	0.895ArgTrp: 0.895 ± 0.015	1.678ArgTyr: 1.678 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.29SerAla: 6.29 ± 0.044	0.936SerCys: 0.936 ± 0.014	3.833SerAsp: 3.833 ± 0.038	4.199SerGlu: 4.199 ± 0.033	2.94SerPhe: 2.94 ± 0.028	5.695SerGly: 5.695 ± 0.042	1.832SerHis: 1.832 ± 0.024	3.972SerIle: 3.972 ± 0.028	3.672SerLys: 3.672 ± 0.029	6.92SerLeu: 6.92 ± 0.044	1.66SerMet: 1.66 ± 0.02	2.942SerAsn: 2.942 ± 0.027	5.815SerPro: 5.815 ± 0.06	2.78SerGln: 2.78 ± 0.032	4.831SerArg: 4.831 ± 0.04	8.951SerSer: 8.951 ± 0.083	5.927SerThr: 5.927 ± 0.04	4.593SerVal: 4.593 ± 0.038	0.985SerTrp: 0.985 ± 0.014	2.11SerTyr: 2.11 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.418ThrAla: 5.418 ± 0.04	0.763ThrCys: 0.763 ± 0.014	2.674ThrAsp: 2.674 ± 0.027	3.23ThrGlu: 3.23 ± 0.031	2.191ThrPhe: 2.191 ± 0.024	4.177ThrGly: 4.177 ± 0.041	1.437ThrHis: 1.437 ± 0.019	3.217ThrIle: 3.217 ± 0.033	2.76ThrLys: 2.76 ± 0.028	5.412ThrLeu: 5.412 ± 0.036	1.154ThrMet: 1.154 ± 0.017	2.201ThrAsn: 2.201 ± 0.025	5.113ThrPro: 5.113 ± 0.049	1.942ThrGln: 1.942 ± 0.023	3.216ThrArg: 3.216 ± 0.028	5.442ThrSer: 5.442 ± 0.041	5.262ThrThr: 5.262 ± 0.064	3.774ThrVal: 3.774 ± 0.037	0.782ThrTrp: 0.782 ± 0.013	1.671ThrTyr: 1.671 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.017ValAla: 5.017 ± 0.04	0.871ValCys: 0.871 ± 0.015	3.563ValAsp: 3.563 ± 0.031	4.563ValGlu: 4.563 ± 0.038	2.41ValPhe: 2.41 ± 0.025	4.44ValGly: 4.44 ± 0.038	1.347ValHis: 1.347 ± 0.02	2.93ValIle: 2.93 ± 0.034	3.282ValLys: 3.282 ± 0.031	5.58ValLeu: 5.58 ± 0.04	1.416ValMet: 1.416 ± 0.018	2.25ValAsn: 2.25 ± 0.023	3.511ValPro: 3.511 ± 0.032	2.121ValGln: 2.121 ± 0.022	3.614ValArg: 3.614 ± 0.03	4.483ValSer: 4.483 ± 0.031	3.478ValThr: 3.478 ± 0.036	4.859ValVal: 4.859 ± 0.04	0.91ValTrp: 0.91 ± 0.015	1.735ValTyr: 1.735 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.02TrpAla: 1.02 ± 0.016	0.209TrpCys: 0.209 ± 0.007	0.813TrpAsp: 0.813 ± 0.014	0.908TrpGlu: 0.908 ± 0.016	0.5TrpPhe: 0.5 ± 0.011	1.026TrpGly: 1.026 ± 0.015	0.302TrpHis: 0.302 ± 0.008	0.706TrpIle: 0.706 ± 0.014	0.79TrpLys: 0.79 ± 0.014	1.205TrpLeu: 1.205 ± 0.015	0.379TrpMet: 0.379 ± 0.01	0.575TrpAsn: 0.575 ± 0.011	0.505TrpPro: 0.505 ± 0.011	0.43TrpGln: 0.43 ± 0.01	0.958TrpArg: 0.958 ± 0.016	0.969TrpSer: 0.969 ± 0.018	0.768TrpThr: 0.768 ± 0.015	0.886TrpVal: 0.886 ± 0.015	0.288TrpTrp: 0.288 ± 0.01	0.398TrpTyr: 0.398 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.936TyrAla: 1.936 ± 0.021	0.449TyrCys: 0.449 ± 0.01	1.581TyrAsp: 1.581 ± 0.019	1.58TyrGlu: 1.58 ± 0.02	1.172TyrPhe: 1.172 ± 0.019	2.039TyrGly: 2.039 ± 0.025	0.775TyrHis: 0.775 ± 0.012	1.523TyrIle: 1.523 ± 0.018	1.213TyrLys: 1.213 ± 0.017	2.618TyrLeu: 2.618 ± 0.028	0.627TyrMet: 0.627 ± 0.012	1.197TyrAsn: 1.197 ± 0.015	1.47TyrPro: 1.47 ± 0.019	1.044TyrGln: 1.044 ± 0.016	1.61TyrArg: 1.61 ± 0.018	2.097TyrSer: 2.097 ± 0.021	1.754TyrThr: 1.754 ± 0.021	1.6TyrVal: 1.6 ± 0.019	0.404TyrTrp: 0.404 ± 0.01	0.967TyrTyr: 0.967 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.024XaaXaa: 0.024 ± 0.009

Statistics based on 11578 proteins (4742244 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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