Amino acid dipepetide frequency for Colletotrichum incanum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.178AlaAla: 10.178 ± 0.059	1.151AlaCys: 1.151 ± 0.014	4.473AlaAsp: 4.473 ± 0.027	5.222AlaGlu: 5.222 ± 0.04	3.263AlaPhe: 3.263 ± 0.025	6.149AlaGly: 6.149 ± 0.039	1.789AlaHis: 1.789 ± 0.018	4.276AlaIle: 4.276 ± 0.034	4.193AlaLys: 4.193 ± 0.033	7.82AlaLeu: 7.82 ± 0.046	2.052AlaMet: 2.052 ± 0.018	3.142AlaAsn: 3.142 ± 0.021	5.104AlaPro: 5.104 ± 0.046	3.404AlaGln: 3.404 ± 0.03	4.956AlaArg: 4.956 ± 0.035	7.544AlaSer: 7.544 ± 0.044	5.578AlaThr: 5.578 ± 0.039	5.806AlaVal: 5.806 ± 0.034	1.278AlaTrp: 1.278 ± 0.016	2.205AlaTyr: 2.205 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.966CysAla: 0.966 ± 0.014	0.269CysCys: 0.269 ± 0.008	0.702CysAsp: 0.702 ± 0.013	0.594CysGlu: 0.594 ± 0.01	0.562CysPhe: 0.562 ± 0.01	0.991CysGly: 0.991 ± 0.016	0.325CysHis: 0.325 ± 0.007	0.717CysIle: 0.717 ± 0.011	0.528CysLys: 0.528 ± 0.01	1.254CysLeu: 1.254 ± 0.013	0.266CysMet: 0.266 ± 0.005	0.475CysAsn: 0.475 ± 0.008	0.699CysPro: 0.699 ± 0.014	0.464CysGln: 0.464 ± 0.009	0.813CysArg: 0.813 ± 0.012	0.969CysSer: 0.969 ± 0.013	0.719CysThr: 0.719 ± 0.013	0.817CysVal: 0.817 ± 0.015	0.22CysTrp: 0.22 ± 0.005	0.349CysTyr: 0.349 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.877AspAla: 4.877 ± 0.03	0.651AspCys: 0.651 ± 0.012	4.23AspAsp: 4.23 ± 0.037	4.29AspGlu: 4.29 ± 0.033	2.27AspPhe: 2.27 ± 0.018	4.209AspGly: 4.209 ± 0.029	1.212AspHis: 1.212 ± 0.013	2.872AspIle: 2.872 ± 0.021	2.412AspLys: 2.412 ± 0.023	4.901AspLeu: 4.901 ± 0.03	1.245AspMet: 1.245 ± 0.014	1.917AspAsn: 1.917 ± 0.017	3.227AspPro: 3.227 ± 0.024	1.774AspGln: 1.774 ± 0.02	2.958AspArg: 2.958 ± 0.03	3.879AspSer: 3.879 ± 0.029	2.872AspThr: 2.872 ± 0.021	3.793AspVal: 3.793 ± 0.026	0.922AspTrp: 0.922 ± 0.014	1.54AspTyr: 1.54 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.534GluAla: 5.534 ± 0.039	0.594GluCys: 0.594 ± 0.01	4.017GluAsp: 4.017 ± 0.033	5.066GluGlu: 5.066 ± 0.048	1.871GluPhe: 1.871 ± 0.019	3.675GluGly: 3.675 ± 0.026	1.345GluHis: 1.345 ± 0.016	2.8GluIle: 2.8 ± 0.025	3.606GluLys: 3.606 ± 0.032	4.911GluLeu: 4.911 ± 0.031	1.38GluMet: 1.38 ± 0.016	2.192GluAsn: 2.192 ± 0.018	2.843GluPro: 2.843 ± 0.043	2.256GluGln: 2.256 ± 0.02	3.702GluArg: 3.702 ± 0.029	3.998GluSer: 3.998 ± 0.026	3.507GluThr: 3.507 ± 0.029	3.561GluVal: 3.561 ± 0.027	0.872GluTrp: 0.872 ± 0.013	1.552GluTyr: 1.552 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.19PheAla: 3.19 ± 0.025	0.586PheCys: 0.586 ± 0.01	2.304PheAsp: 2.304 ± 0.02	2.096PheGlu: 2.096 ± 0.023	1.732PhePhe: 1.732 ± 0.02	2.978PheGly: 2.978 ± 0.027	0.903PheHis: 0.903 ± 0.012	1.823PheIle: 1.823 ± 0.019	1.533PheLys: 1.533 ± 0.016	3.491PheLeu: 3.491 ± 0.03	0.782PheMet: 0.782 ± 0.012	1.513PheAsn: 1.513 ± 0.016	1.988PhePro: 1.988 ± 0.019	1.364PheGln: 1.364 ± 0.016	1.959PheArg: 1.959 ± 0.017	3.043PheSer: 3.043 ± 0.023	2.207PheThr: 2.207 ± 0.022	2.493PheVal: 2.493 ± 0.021	0.669PheTrp: 0.669 ± 0.01	1.122PheTyr: 1.122 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.678GlyAla: 5.678 ± 0.037	0.933GlyCys: 0.933 ± 0.015	3.66GlyAsp: 3.66 ± 0.03	3.514GlyGlu: 3.514 ± 0.026	2.913GlyPhe: 2.913 ± 0.027	6.176GlyGly: 6.176 ± 0.062	1.734GlyHis: 1.734 ± 0.018	3.558GlyIle: 3.558 ± 0.025	3.423GlyLys: 3.423 ± 0.027	6.202GlyLeu: 6.202 ± 0.031	1.582GlyMet: 1.582 ± 0.017	2.675GlyAsn: 2.675 ± 0.025	3.493GlyPro: 3.493 ± 0.028	2.599GlyGln: 2.599 ± 0.02	4.195GlyArg: 4.195 ± 0.03	5.752GlySer: 5.752 ± 0.038	4.143GlyThr: 4.143 ± 0.05	4.536GlyVal: 4.536 ± 0.033	1.223GlyTrp: 1.223 ± 0.017	2.124GlyTyr: 2.124 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.836HisAla: 1.836 ± 0.018	0.359HisCys: 0.359 ± 0.008	1.282HisAsp: 1.282 ± 0.013	1.268HisGlu: 1.268 ± 0.016	0.923HisPhe: 0.923 ± 0.012	1.701HisGly: 1.701 ± 0.019	0.909HisHis: 0.909 ± 0.016	1.149HisIle: 1.149 ± 0.013	0.916HisLys: 0.916 ± 0.012	2.207HisLeu: 2.207 ± 0.02	0.488HisMet: 0.488 ± 0.009	0.859HisAsn: 0.859 ± 0.011	1.667HisPro: 1.667 ± 0.017	1.022HisGln: 1.022 ± 0.016	1.548HisArg: 1.548 ± 0.019	1.773HisSer: 1.773 ± 0.02	1.251HisThr: 1.251 ± 0.017	1.465HisVal: 1.465 ± 0.018	0.352HisTrp: 0.352 ± 0.009	0.676HisTyr: 0.676 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.208IleAla: 4.208 ± 0.031	0.719IleCys: 0.719 ± 0.011	2.744IleAsp: 2.744 ± 0.022	2.726IleGlu: 2.726 ± 0.023	1.946IlePhe: 1.946 ± 0.02	3.223IleGly: 3.223 ± 0.029	1.157IleHis: 1.157 ± 0.013	2.465IleIle: 2.465 ± 0.025	2.151IleLys: 2.151 ± 0.02	4.366IleLeu: 4.366 ± 0.032	1.039IleMet: 1.039 ± 0.013	1.781IleAsn: 1.781 ± 0.017	2.956IlePro: 2.956 ± 0.024	1.81IleGln: 1.81 ± 0.019	2.719IleArg: 2.719 ± 0.022	3.664IleSer: 3.664 ± 0.026	2.825IleThr: 2.825 ± 0.026	3.207IleVal: 3.207 ± 0.024	0.74IleTrp: 0.74 ± 0.011	1.332IleTyr: 1.332 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.354LysAla: 4.354 ± 0.033	0.516LysCys: 0.516 ± 0.01	2.766LysAsp: 2.766 ± 0.024	3.245LysGlu: 3.245 ± 0.031	1.453LysPhe: 1.453 ± 0.017	3.009LysGly: 3.009 ± 0.028	1.104LysHis: 1.104 ± 0.013	2.195LysIle: 2.195 ± 0.022	3.34LysLys: 3.34 ± 0.042	4.025LysLeu: 4.025 ± 0.029	1.053LysMet: 1.053 ± 0.015	1.777LysAsn: 1.777 ± 0.019	2.797LysPro: 2.797 ± 0.024	1.792LysGln: 1.792 ± 0.019	3.245LysArg: 3.245 ± 0.029	3.418LysSer: 3.418 ± 0.026	2.97LysThr: 2.97 ± 0.022	2.844LysVal: 2.844 ± 0.025	0.693LysTrp: 0.693 ± 0.011	1.307LysTyr: 1.307 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.067LeuAla: 8.067 ± 0.037	1.209LeuCys: 1.209 ± 0.015	4.978LeuAsp: 4.978 ± 0.032	5.246LeuGlu: 5.246 ± 0.035	3.362LeuPhe: 3.362 ± 0.029	6.097LeuGly: 6.097 ± 0.038	2.169LeuHis: 2.169 ± 0.021	3.787LeuIle: 3.787 ± 0.028	4.034LeuLys: 4.034 ± 0.03	8.251LeuLeu: 8.251 ± 0.052	1.744LeuMet: 1.744 ± 0.019	3.078LeuAsn: 3.078 ± 0.026	5.617LeuPro: 5.617 ± 0.04	3.68LeuGln: 3.68 ± 0.031	5.762LeuArg: 5.762 ± 0.038	7.074LeuSer: 7.074 ± 0.039	4.927LeuThr: 4.927 ± 0.034	5.572LeuVal: 5.572 ± 0.036	1.259LeuTrp: 1.259 ± 0.016	2.282LeuTyr: 2.282 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.335MetAla: 2.335 ± 0.02	0.236MetCys: 0.236 ± 0.007	1.202MetAsp: 1.202 ± 0.015	1.223MetGlu: 1.223 ± 0.014	0.772MetPhe: 0.772 ± 0.01	1.466MetGly: 1.466 ± 0.017	0.462MetHis: 0.462 ± 0.009	0.957MetIle: 0.957 ± 0.013	1.007MetLys: 1.007 ± 0.013	1.819MetLeu: 1.819 ± 0.019	0.591MetMet: 0.591 ± 0.009	0.781MetAsn: 0.781 ± 0.012	1.315MetPro: 1.315 ± 0.014	0.813MetGln: 0.813 ± 0.011	1.275MetArg: 1.275 ± 0.015	1.86MetSer: 1.86 ± 0.018	1.339MetThr: 1.339 ± 0.014	1.331MetVal: 1.331 ± 0.014	0.279MetTrp: 0.279 ± 0.007	0.516MetTyr: 0.516 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.19AsnAla: 3.19 ± 0.025	0.471AsnCys: 0.471 ± 0.009	1.968AsnAsp: 1.968 ± 0.017	1.957AsnGlu: 1.957 ± 0.015	1.445AsnPhe: 1.445 ± 0.017	3.142AsnGly: 3.142 ± 0.027	0.87AsnHis: 0.87 ± 0.014	2.011AsnIle: 2.011 ± 0.019	1.612AsnLys: 1.612 ± 0.016	3.279AsnLeu: 3.279 ± 0.024	0.863AsnMet: 0.863 ± 0.012	1.582AsnAsn: 1.582 ± 0.025	2.464AsnPro: 2.464 ± 0.021	1.355AsnGln: 1.355 ± 0.016	1.93AsnArg: 1.93 ± 0.019	2.695AsnSer: 2.695 ± 0.025	2.215AsnThr: 2.215 ± 0.02	2.317AsnVal: 2.317 ± 0.022	0.578AsnTrp: 0.578 ± 0.01	1.054AsnTyr: 1.054 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.673ProAla: 5.673 ± 0.053	0.555ProCys: 0.555 ± 0.009	3.172ProAsp: 3.172 ± 0.025	3.846ProGlu: 3.846 ± 0.039	2.11ProPhe: 2.11 ± 0.019	4.05ProGly: 4.05 ± 0.035	1.309ProHis: 1.309 ± 0.016	2.538ProIle: 2.538 ± 0.02	2.756ProLys: 2.756 ± 0.025	4.779ProLeu: 4.779 ± 0.032	1.082ProMet: 1.082 ± 0.014	2.259ProAsn: 2.259 ± 0.022	5.35ProPro: 5.35 ± 0.068	2.489ProGln: 2.489 ± 0.027	3.575ProArg: 3.575 ± 0.029	5.9ProSer: 5.9 ± 0.04	4.179ProThr: 4.179 ± 0.04	3.734ProVal: 3.734 ± 0.031	0.791ProTrp: 0.791 ± 0.014	1.464ProTyr: 1.464 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.485GlnAla: 3.485 ± 0.027	0.473GlnCys: 0.473 ± 0.009	1.986GlnAsp: 1.986 ± 0.018	2.234GlnGlu: 2.234 ± 0.024	1.254GlnPhe: 1.254 ± 0.017	2.406GlnGly: 2.406 ± 0.021	1.11GlnHis: 1.11 ± 0.016	1.784GlnIle: 1.784 ± 0.018	1.893GlnLys: 1.893 ± 0.018	3.386GlnLeu: 3.386 ± 0.027	0.883GlnMet: 0.883 ± 0.014	1.487GlnAsn: 1.487 ± 0.016	2.627GlnPro: 2.627 ± 0.029	2.597GlnGln: 2.597 ± 0.049	2.612GlnArg: 2.612 ± 0.025	2.933GlnSer: 2.933 ± 0.024	2.36GlnThr: 2.36 ± 0.025	2.146GlnVal: 2.146 ± 0.02	0.579GlnTrp: 0.579 ± 0.009	1.123GlnTyr: 1.123 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.701ArgAla: 4.701 ± 0.035	0.772ArgCys: 0.772 ± 0.011	3.361ArgAsp: 3.361 ± 0.027	3.607ArgGlu: 3.607 ± 0.029	2.133ArgPhe: 2.133 ± 0.023	3.758ArgGly: 3.758 ± 0.029	1.632ArgHis: 1.632 ± 0.02	2.786ArgIle: 2.786 ± 0.021	3.358ArgLys: 3.358 ± 0.027	5.492ArgLeu: 5.492 ± 0.038	1.265ArgMet: 1.265 ± 0.015	2.257ArgAsn: 2.257 ± 0.022	3.693ArgPro: 3.693 ± 0.032	2.666ArgGln: 2.666 ± 0.023	5.192ArgArg: 5.192 ± 0.046	4.703ArgSer: 4.703 ± 0.034	3.325ArgThr: 3.325 ± 0.024	3.396ArgVal: 3.396 ± 0.029	0.975ArgTrp: 0.975 ± 0.015	1.605ArgTyr: 1.605 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.722SerAla: 6.722 ± 0.039	0.937SerCys: 0.937 ± 0.013	4.065SerAsp: 4.065 ± 0.031	3.893SerGlu: 3.893 ± 0.03	3.091SerPhe: 3.091 ± 0.024	5.566SerGly: 5.566 ± 0.039	1.89SerHis: 1.89 ± 0.02	3.843SerIle: 3.843 ± 0.028	3.599SerLys: 3.599 ± 0.029	7.055SerLeu: 7.055 ± 0.036	1.669SerMet: 1.669 ± 0.018	2.951SerAsn: 2.951 ± 0.022	5.459SerPro: 5.459 ± 0.042	3.217SerGln: 3.217 ± 0.028	4.969SerArg: 4.969 ± 0.04	8.395SerSer: 8.395 ± 0.065	5.53SerThr: 5.53 ± 0.053	4.674SerVal: 4.674 ± 0.032	1.177SerTrp: 1.177 ± 0.012	2.042SerTyr: 2.042 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.556ThrAla: 5.556 ± 0.038	0.783ThrCys: 0.783 ± 0.012	2.85ThrAsp: 2.85 ± 0.022	3.112ThrGlu: 3.112 ± 0.025	2.28ThrPhe: 2.28 ± 0.02	4.289ThrGly: 4.289 ± 0.042	1.257ThrHis: 1.257 ± 0.015	3.121ThrIle: 3.121 ± 0.035	2.7ThrLys: 2.7 ± 0.025	5.201ThrLeu: 5.201 ± 0.038	1.303ThrMet: 1.303 ± 0.013	2.209ThrAsn: 2.209 ± 0.022	4.428ThrPro: 4.428 ± 0.042	2.102ThrGln: 2.102 ± 0.021	3.181ThrArg: 3.181 ± 0.022	5.389ThrSer: 5.389 ± 0.052	4.581ThrThr: 4.581 ± 0.061	3.934ThrVal: 3.934 ± 0.048	0.913ThrTrp: 0.913 ± 0.013	1.663ThrTyr: 1.663 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.67ValAla: 5.67 ± 0.035	0.85ValCys: 0.85 ± 0.012	3.713ValAsp: 3.713 ± 0.026	3.824ValGlu: 3.824 ± 0.026	2.622ValPhe: 2.622 ± 0.023	4.165ValGly: 4.165 ± 0.033	1.345ValHis: 1.345 ± 0.017	2.997ValIle: 2.997 ± 0.031	2.946ValLys: 2.946 ± 0.023	5.766ValLeu: 5.766 ± 0.04	1.341ValMet: 1.341 ± 0.014	2.26ValAsn: 2.26 ± 0.02	3.764ValPro: 3.764 ± 0.031	2.317ValGln: 2.317 ± 0.02	3.511ValArg: 3.511 ± 0.029	4.713ValSer: 4.713 ± 0.031	3.759ValThr: 3.759 ± 0.039	4.628ValVal: 4.628 ± 0.042	0.938ValTrp: 0.938 ± 0.012	1.735ValTyr: 1.735 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.233TrpAla: 1.233 ± 0.014	0.21TrpCys: 0.21 ± 0.006	0.93TrpAsp: 0.93 ± 0.013	0.858TrpGlu: 0.858 ± 0.013	0.588TrpPhe: 0.588 ± 0.011	0.975TrpGly: 0.975 ± 0.013	0.391TrpHis: 0.391 ± 0.008	0.765TrpIle: 0.765 ± 0.012	0.823TrpLys: 0.823 ± 0.012	1.402TrpLeu: 1.402 ± 0.015	0.374TrpMet: 0.374 ± 0.009	0.677TrpAsn: 0.677 ± 0.011	0.675TrpPro: 0.675 ± 0.011	0.595TrpGln: 0.595 ± 0.01	0.976TrpArg: 0.976 ± 0.014	1.081TrpSer: 1.081 ± 0.013	0.973TrpThr: 0.973 ± 0.014	0.943TrpVal: 0.943 ± 0.014	0.306TrpTrp: 0.306 ± 0.007	0.458TrpTyr: 0.458 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.132TyrAla: 2.132 ± 0.017	0.425TyrCys: 0.425 ± 0.009	1.65TyrAsp: 1.65 ± 0.019	1.459TyrGlu: 1.459 ± 0.015	1.186TyrPhe: 1.186 ± 0.015	2.089TyrGly: 2.089 ± 0.022	0.738TyrHis: 0.738 ± 0.011	1.333TyrIle: 1.333 ± 0.016	1.073TyrLys: 1.073 ± 0.014	2.584TyrLeu: 2.584 ± 0.023	0.578TyrMet: 0.578 ± 0.009	1.123TyrAsn: 1.123 ± 0.013	1.446TyrPro: 1.446 ± 0.018	1.044TyrGln: 1.044 ± 0.014	1.602TyrArg: 1.602 ± 0.016	1.96TyrSer: 1.96 ± 0.018	1.593TyrThr: 1.593 ± 0.019	1.665TyrVal: 1.665 ± 0.018	0.469TyrTrp: 0.469 ± 0.009	0.898TyrTyr: 0.898 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 12795 proteins (6394483 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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