Amino acid dipepetide frequency for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.651AlaAla: 8.651 ± 0.119	0.993AlaCys: 0.993 ± 0.024	4.093AlaAsp: 4.093 ± 0.057	5.035AlaGlu: 5.035 ± 0.058	2.645AlaPhe: 2.645 ± 0.038	5.225AlaGly: 5.225 ± 0.073	1.778AlaHis: 1.778 ± 0.031	3.68AlaIle: 3.68 ± 0.044	4.098AlaLys: 4.098 ± 0.051	7.656AlaLeu: 7.656 ± 0.075	1.661AlaMet: 1.661 ± 0.027	2.756AlaAsn: 2.756 ± 0.037	3.961AlaPro: 3.961 ± 0.063	3.245AlaGln: 3.245 ± 0.055	4.664AlaArg: 4.664 ± 0.065	6.006AlaSer: 6.006 ± 0.067	4.354AlaThr: 4.354 ± 0.047	5.328AlaVal: 5.328 ± 0.062	0.726AlaTrp: 0.726 ± 0.019	2.143AlaTyr: 2.143 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	1.016CysAla: 1.016 ± 0.023	0.281CysCys: 0.281 ± 0.012	0.728CysAsp: 0.728 ± 0.021	0.698CysGlu: 0.698 ± 0.018	0.582CysPhe: 0.582 ± 0.018	1.039CysGly: 1.039 ± 0.023	0.35CysHis: 0.35 ± 0.013	0.819CysIle: 0.819 ± 0.021	0.679CysLys: 0.679 ± 0.02	1.287CysLeu: 1.287 ± 0.026	0.32CysMet: 0.32 ± 0.013	0.551CysAsn: 0.551 ± 0.016	0.562CysPro: 0.562 ± 0.019	0.465CysGln: 0.465 ± 0.015	0.753CysArg: 0.753 ± 0.016	1.128CysSer: 1.128 ± 0.023	0.693CysThr: 0.693 ± 0.021	0.955CysVal: 0.955 ± 0.023	0.176CysTrp: 0.176 ± 0.007	0.489CysTyr: 0.489 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.418AspAla: 4.418 ± 0.051	0.683AspCys: 0.683 ± 0.018	4.066AspAsp: 4.066 ± 0.074	4.735AspGlu: 4.735 ± 0.058	2.359AspPhe: 2.359 ± 0.032	3.494AspGly: 3.494 ± 0.051	1.12AspHis: 1.12 ± 0.021	3.394AspIle: 3.394 ± 0.045	2.771AspLys: 2.771 ± 0.05	5.295AspLeu: 5.295 ± 0.052	1.294AspMet: 1.294 ± 0.023	2.132AspAsn: 2.132 ± 0.035	2.712AspPro: 2.712 ± 0.034	1.745AspGln: 1.745 ± 0.029	2.664AspArg: 2.664 ± 0.032	4.281AspSer: 4.281 ± 0.054	2.898AspThr: 2.898 ± 0.037	3.783AspVal: 3.783 ± 0.045	0.673AspTrp: 0.673 ± 0.019	2.033AspTyr: 2.033 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	4.73GluAla: 4.73 ± 0.06	0.721GluCys: 0.721 ± 0.02	4.215GluAsp: 4.215 ± 0.053	5.736GluGlu: 5.736 ± 0.07	2.546GluPhe: 2.546 ± 0.033	3.285GluGly: 3.285 ± 0.042	1.704GluHis: 1.704 ± 0.028	3.115GluIle: 3.115 ± 0.041	3.953GluLys: 3.953 ± 0.05	7.36GluLeu: 7.36 ± 0.068	1.365GluMet: 1.365 ± 0.025	2.792GluAsn: 2.792 ± 0.036	2.496GluPro: 2.496 ± 0.035	3.261GluGln: 3.261 ± 0.038	4.14GluArg: 4.14 ± 0.052	4.28GluSer: 4.28 ± 0.049	3.261GluThr: 3.261 ± 0.041	3.89GluVal: 3.89 ± 0.043	0.699GluTrp: 0.699 ± 0.017	2.244GluTyr: 2.244 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	2.738PheAla: 2.738 ± 0.038	0.557PheCys: 0.557 ± 0.017	2.36PheAsp: 2.36 ± 0.033	2.524PheGlu: 2.524 ± 0.035	1.665PhePhe: 1.665 ± 0.033	2.568PheGly: 2.568 ± 0.047	0.998PheHis: 0.998 ± 0.023	2.108PheIle: 2.108 ± 0.039	2.175PheLys: 2.175 ± 0.034	3.801PheLeu: 3.801 ± 0.051	0.895PheMet: 0.895 ± 0.024	1.802PheAsn: 1.802 ± 0.031	1.679PhePro: 1.679 ± 0.032	1.724PheGln: 1.724 ± 0.028	2.012PheArg: 2.012 ± 0.031	3.086PheSer: 3.086 ± 0.042	2.146PheThr: 2.146 ± 0.033	2.627PheVal: 2.627 ± 0.037	0.483PheTrp: 0.483 ± 0.017	1.442PheTyr: 1.442 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	4.952GlyAla: 4.952 ± 0.068	0.871GlyCys: 0.871 ± 0.018	3.198GlyAsp: 3.198 ± 0.037	3.47GlyGlu: 3.47 ± 0.044	2.33GlyPhe: 2.33 ± 0.033	4.439GlyGly: 4.439 ± 0.075	1.461GlyHis: 1.461 ± 0.03	3.179GlyIle: 3.179 ± 0.041	3.419GlyLys: 3.419 ± 0.046	5.311GlyLeu: 5.311 ± 0.055	1.254GlyMet: 1.254 ± 0.027	2.371GlyAsn: 2.371 ± 0.033	2.325GlyPro: 2.325 ± 0.035	2.144GlyGln: 2.144 ± 0.038	3.405GlyArg: 3.405 ± 0.045	5.301GlySer: 5.301 ± 0.06	3.511GlyThr: 3.511 ± 0.046	3.884GlyVal: 3.884 ± 0.05	0.712GlyTrp: 0.712 ± 0.021	1.971GlyTyr: 1.971 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	1.715HisAla: 1.715 ± 0.031	0.349HisCys: 0.349 ± 0.013	1.278HisAsp: 1.278 ± 0.028	1.45HisGlu: 1.45 ± 0.029	0.995HisPhe: 0.995 ± 0.019	1.592HisGly: 1.592 ± 0.029	0.714HisHis: 0.714 ± 0.022	1.331HisIle: 1.331 ± 0.025	1.142HisLys: 1.142 ± 0.024	2.353HisLeu: 2.353 ± 0.036	0.607HisMet: 0.607 ± 0.018	0.922HisAsn: 0.922 ± 0.019	1.208HisPro: 1.208 ± 0.025	0.904HisGln: 0.904 ± 0.023	1.383HisArg: 1.383 ± 0.024	1.953HisSer: 1.953 ± 0.03	1.282HisThr: 1.282 ± 0.023	1.584HisVal: 1.584 ± 0.026	0.29HisTrp: 0.29 ± 0.01	0.829HisTyr: 0.829 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	3.55IleAla: 3.55 ± 0.042	0.788IleCys: 0.788 ± 0.02	3.004IleAsp: 3.004 ± 0.041	3.166IleGlu: 3.166 ± 0.045	2.086IlePhe: 2.086 ± 0.041	2.723IleGly: 2.723 ± 0.036	1.146IleHis: 1.146 ± 0.023	2.68IleIle: 2.68 ± 0.044	2.903IleLys: 2.903 ± 0.036	4.915IleLeu: 4.915 ± 0.064	1.135IleMet: 1.135 ± 0.022	2.299IleAsn: 2.299 ± 0.036	2.69IlePro: 2.69 ± 0.038	1.952IleGln: 1.952 ± 0.034	2.688IleArg: 2.688 ± 0.039	4.253IleSer: 4.253 ± 0.055	2.855IleThr: 2.855 ± 0.043	3.249IleVal: 3.249 ± 0.042	0.602IleTrp: 0.602 ± 0.018	1.718IleTyr: 1.718 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.783LysAla: 3.783 ± 0.049	0.664LysCys: 0.664 ± 0.018	3.083LysAsp: 3.083 ± 0.052	3.748LysGlu: 3.748 ± 0.049	2.234LysPhe: 2.234 ± 0.033	2.595LysGly: 2.595 ± 0.037	1.432LysHis: 1.432 ± 0.028	2.894LysIle: 2.894 ± 0.037	4.255LysLys: 4.255 ± 0.058	6.103LysLeu: 6.103 ± 0.059	1.273LysMet: 1.273 ± 0.027	2.539LysAsn: 2.539 ± 0.04	2.569LysPro: 2.569 ± 0.044	2.498LysGln: 2.498 ± 0.036	3.778LysArg: 3.778 ± 0.048	3.904LysSer: 3.904 ± 0.057	3.005LysThr: 3.005 ± 0.041	3.547LysVal: 3.547 ± 0.041	0.657LysTrp: 0.657 ± 0.018	2.077LysTyr: 2.077 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	7.727LeuAla: 7.727 ± 0.074	1.479LeuCys: 1.479 ± 0.03	5.65LeuAsp: 5.65 ± 0.059	6.683LeuGlu: 6.683 ± 0.073	3.997LeuPhe: 3.997 ± 0.054	5.4LeuGly: 5.4 ± 0.056	2.506LeuHis: 2.506 ± 0.035	4.355LeuIle: 4.355 ± 0.056	5.882LeuLys: 5.882 ± 0.059	10.738LeuLeu: 10.738 ± 0.101	1.992LeuMet: 1.992 ± 0.031	4.2LeuAsn: 4.2 ± 0.053	5.175LeuPro: 5.175 ± 0.048	4.974LeuGln: 4.974 ± 0.059	6.169LeuArg: 6.169 ± 0.06	7.852LeuSer: 7.852 ± 0.062	5.01LeuThr: 5.01 ± 0.053	6.35LeuVal: 6.35 ± 0.069	1.048LeuTrp: 1.048 ± 0.024	3.109LeuTyr: 3.109 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	1.762MetAla: 1.762 ± 0.031	0.322MetCys: 0.322 ± 0.013	1.311MetAsp: 1.311 ± 0.023	1.359MetGlu: 1.359 ± 0.025	0.824MetPhe: 0.824 ± 0.021	1.266MetGly: 1.266 ± 0.024	0.495MetHis: 0.495 ± 0.015	1.015MetIle: 1.015 ± 0.024	1.282MetLys: 1.282 ± 0.025	2.274MetLeu: 2.274 ± 0.033	0.518MetMet: 0.518 ± 0.017	0.971MetAsn: 0.971 ± 0.022	0.998MetPro: 0.998 ± 0.025	0.924MetGln: 0.924 ± 0.019	1.222MetArg: 1.222 ± 0.024	1.966MetSer: 1.966 ± 0.028	1.109MetThr: 1.109 ± 0.021	1.381MetVal: 1.381 ± 0.03	0.218MetTrp: 0.218 ± 0.011	0.635MetTyr: 0.635 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.865AsnAla: 2.865 ± 0.035	0.584AsnCys: 0.584 ± 0.017	2.274AsnAsp: 2.274 ± 0.031	2.547AsnGlu: 2.547 ± 0.033	1.72AsnPhe: 1.72 ± 0.028	2.663AsnGly: 2.663 ± 0.04	0.856AsnHis: 0.856 ± 0.022	2.481AsnIle: 2.481 ± 0.047	2.459AsnLys: 2.459 ± 0.033	3.726AsnLeu: 3.726 ± 0.045	1.052AsnMet: 1.052 ± 0.02	1.966AsnAsn: 1.966 ± 0.041	1.992AsnPro: 1.992 ± 0.032	1.388AsnGln: 1.388 ± 0.026	2.005AsnArg: 2.005 ± 0.03	3.439AsnSer: 3.439 ± 0.045	2.353AsnThr: 2.353 ± 0.037	2.706AsnVal: 2.706 ± 0.036	0.504AsnTrp: 0.504 ± 0.019	1.488AsnTyr: 1.488 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	4.406ProAla: 4.406 ± 0.07	0.476ProCys: 0.476 ± 0.02	2.543ProAsp: 2.543 ± 0.036	3.455ProGlu: 3.455 ± 0.041	1.775ProPhe: 1.775 ± 0.026	2.794ProGly: 2.794 ± 0.039	1.154ProHis: 1.154 ± 0.023	2.179ProIle: 2.179 ± 0.032	2.371ProLys: 2.371 ± 0.041	4.549ProLeu: 4.549 ± 0.049	0.948ProMet: 0.948 ± 0.021	1.739ProAsn: 1.739 ± 0.03	3.164ProPro: 3.164 ± 0.076	2.211ProGln: 2.211 ± 0.046	2.633ProArg: 2.633 ± 0.042	4.167ProSer: 4.167 ± 0.067	2.831ProThr: 2.831 ± 0.04	3.368ProVal: 3.368 ± 0.046	0.478ProTrp: 0.478 ± 0.014	1.388ProTyr: 1.388 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.039GlnAla: 3.039 ± 0.045	0.543GlnCys: 0.543 ± 0.016	2.156GlnAsp: 2.156 ± 0.035	2.829GlnGlu: 2.829 ± 0.04	1.631GlnPhe: 1.631 ± 0.029	2.162GlnGly: 2.162 ± 0.038	1.158GlnHis: 1.158 ± 0.031	1.893GlnIle: 1.893 ± 0.029	2.296GlnLys: 2.296 ± 0.035	5.145GlnLeu: 5.145 ± 0.054	0.914GlnMet: 0.914 ± 0.021	1.579GlnAsn: 1.579 ± 0.027	2.09GlnPro: 2.09 ± 0.046	3.195GlnGln: 3.195 ± 0.154	2.795GlnArg: 2.795 ± 0.038	2.821GlnSer: 2.821 ± 0.044	1.975GlnThr: 1.975 ± 0.034	2.472GlnVal: 2.472 ± 0.034	0.493GlnTrp: 0.493 ± 0.015	1.421GlnTyr: 1.421 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	4.632ArgAla: 4.632 ± 0.064	0.821ArgCys: 0.821 ± 0.022	3.09ArgAsp: 3.09 ± 0.042	3.867ArgGlu: 3.867 ± 0.044	2.226ArgPhe: 2.226 ± 0.032	3.249ArgGly: 3.249 ± 0.05	1.419ArgHis: 1.419 ± 0.024	2.941ArgIle: 2.941 ± 0.039	3.614ArgLys: 3.614 ± 0.042	5.749ArgLeu: 5.749 ± 0.053	1.254ArgMet: 1.254 ± 0.025	2.342ArgAsn: 2.342 ± 0.035	2.527ArgPro: 2.527 ± 0.039	2.507ArgGln: 2.507 ± 0.034	4.556ArgArg: 4.556 ± 0.065	4.283ArgSer: 4.283 ± 0.05	3.002ArgThr: 3.002 ± 0.041	3.384ArgVal: 3.384 ± 0.046	0.719ArgTrp: 0.719 ± 0.017	2.014ArgTyr: 2.014 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	6.235SerAla: 6.235 ± 0.065	0.99SerCys: 0.99 ± 0.024	4.23SerAsp: 4.23 ± 0.055	4.5SerGlu: 4.5 ± 0.055	3.084SerPhe: 3.084 ± 0.042	5.046SerGly: 5.046 ± 0.056	1.748SerHis: 1.748 ± 0.028	4.093SerIle: 4.093 ± 0.049	4.524SerLys: 4.524 ± 0.045	7.511SerLeu: 7.511 ± 0.069	1.807SerMet: 1.807 ± 0.031	3.362SerAsn: 3.362 ± 0.049	4.022SerPro: 4.022 ± 0.065	3.122SerGln: 3.122 ± 0.048	4.201SerArg: 4.201 ± 0.047	8.099SerSer: 8.099 ± 0.106	4.9SerThr: 4.9 ± 0.07	5.038SerVal: 5.038 ± 0.061	0.826SerTrp: 0.826 ± 0.019	2.316SerTyr: 2.316 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	4.354ThrAla: 4.354 ± 0.047	0.719ThrCys: 0.719 ± 0.019	2.728ThrAsp: 2.728 ± 0.034	3.153ThrGlu: 3.153 ± 0.039	2.107ThrPhe: 2.107 ± 0.035	3.588ThrGly: 3.588 ± 0.055	1.223ThrHis: 1.223 ± 0.022	2.833ThrIle: 2.833 ± 0.042	2.96ThrLys: 2.96 ± 0.037	5.385ThrLeu: 5.385 ± 0.052	1.184ThrMet: 1.184 ± 0.022	2.189ThrAsn: 2.189 ± 0.03	3.148ThrPro: 3.148 ± 0.056	1.975ThrGln: 1.975 ± 0.035	2.85ThrArg: 2.85 ± 0.034	4.541ThrSer: 4.541 ± 0.067	3.382ThrThr: 3.382 ± 0.127	3.837ThrVal: 3.837 ± 0.052	0.621ThrTrp: 0.621 ± 0.019	1.63ThrTyr: 1.63 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	5.176ValAla: 5.176 ± 0.058	0.943ValCys: 0.943 ± 0.021	3.833ValAsp: 3.833 ± 0.048	4.126ValGlu: 4.126 ± 0.044	2.675ValPhe: 2.675 ± 0.038	3.708ValGly: 3.708 ± 0.049	1.515ValHis: 1.515 ± 0.027	3.157ValIle: 3.157 ± 0.039	3.375ValLys: 3.375 ± 0.045	6.656ValLeu: 6.656 ± 0.058	1.302ValMet: 1.302 ± 0.027	2.492ValAsn: 2.492 ± 0.033	3.567ValPro: 3.567 ± 0.055	2.538ValGln: 2.538 ± 0.032	3.756ValArg: 3.756 ± 0.051	5.034ValSer: 5.034 ± 0.051	3.593ValThr: 3.593 ± 0.062	4.732ValVal: 4.732 ± 0.057	0.716ValTrp: 0.716 ± 0.019	2.029ValTyr: 2.029 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	0.756TrpAla: 0.756 ± 0.019	0.271TrpCys: 0.271 ± 0.011	0.723TrpAsp: 0.723 ± 0.021	0.682TrpGlu: 0.682 ± 0.017	0.494TrpPhe: 0.494 ± 0.018	0.598TrpGly: 0.598 ± 0.019	0.281TrpHis: 0.281 ± 0.011	0.532TrpIle: 0.532 ± 0.017	0.714TrpLys: 0.714 ± 0.018	1.154TrpLeu: 1.154 ± 0.025	0.257TrpMet: 0.257 ± 0.011	0.565TrpAsn: 0.565 ± 0.016	0.387TrpPro: 0.387 ± 0.013	0.475TrpGln: 0.475 ± 0.014	0.743TrpArg: 0.743 ± 0.02	0.837TrpSer: 0.837 ± 0.018	0.56TrpThr: 0.56 ± 0.017	0.608TrpVal: 0.608 ± 0.015	0.181TrpTrp: 0.181 ± 0.01	0.406TrpTyr: 0.406 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.195TyrAla: 2.195 ± 0.033	0.516TyrCys: 0.516 ± 0.014	1.988TyrAsp: 1.988 ± 0.034	2.031TyrGlu: 2.031 ± 0.032	1.42TyrPhe: 1.42 ± 0.025	2.073TyrGly: 2.073 ± 0.034	0.823TyrHis: 0.823 ± 0.02	1.723TyrIle: 1.723 ± 0.034	1.763TyrLys: 1.763 ± 0.031	3.325TyrLeu: 3.325 ± 0.046	0.821TyrMet: 0.821 ± 0.021	1.498TyrAsn: 1.498 ± 0.027	1.358TyrPro: 1.358 ± 0.028	1.36TyrGln: 1.36 ± 0.026	1.778TyrArg: 1.778 ± 0.029	2.427TyrSer: 2.427 ± 0.036	1.682TyrThr: 1.682 ± 0.029	2.2TyrVal: 2.2 ± 0.033	0.402TyrTrp: 0.402 ± 0.013	1.336TyrTyr: 1.336 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4760 proteins (2330700 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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