Amino acid dipepetide frequency for Trematomus pennellii polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.151AlaAla: 14.151 ± 4.811
1.179AlaCys: 1.179 ± 0.814
4.127AlaAsp: 4.127 ± 1.45
7.665AlaGlu: 7.665 ± 3.282
2.358AlaPhe: 2.358 ± 0.456
7.075AlaGly: 7.075 ± 4.315
2.948AlaHis: 2.948 ± 1.067
4.717AlaIle: 4.717 ± 1.376
5.896AlaLys: 5.896 ± 1.027
5.896AlaLeu: 5.896 ± 2.879
2.948AlaMet: 2.948 ± 1.466
1.179AlaAsn: 1.179 ± 0.814
4.127AlaPro: 4.127 ± 0.915
0.59AlaGln: 0.59 ± 0.464
4.717AlaArg: 4.717 ± 1.376
7.665AlaSer: 7.665 ± 1.849
8.255AlaThr: 8.255 ± 1.709
8.255AlaVal: 8.255 ± 3.126
0.59AlaTrp: 0.59 ± 0.788
1.179AlaTyr: 1.179 ± 0.45
0.0AlaXaa: 0.0 ± 0.0
Cys
2.358CysAla: 2.358 ± 1.628
1.179CysCys: 1.179 ± 5.633
1.769CysAsp: 1.769 ± 1.221
0.0CysGlu: 0.0 ± 0.0
1.769CysPhe: 1.769 ± 2.672
0.0CysGly: 0.0 ± 0.0
1.179CysHis: 1.179 ± 0.814
0.0CysIle: 0.0 ± 0.0
0.59CysLys: 0.59 ± 0.407
1.179CysLeu: 1.179 ± 0.814
0.59CysMet: 0.59 ± 2.817
0.0CysAsn: 0.0 ± 0.0
2.358CysPro: 2.358 ± 2.638
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.59CysSer: 0.59 ± 2.817
1.769CysThr: 1.769 ± 1.221
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.59CysTyr: 0.59 ± 0.788
0.0CysXaa: 0.0 ± 0.0
Asp
5.896AspAla: 5.896 ± 1.558
0.59AspCys: 0.59 ± 0.407
4.717AspAsp: 4.717 ± 1.273
6.486AspGlu: 6.486 ± 1.943
2.948AspPhe: 2.948 ± 1.466
2.948AspGly: 2.948 ± 0.713
0.59AspHis: 0.59 ± 0.407
5.307AspIle: 5.307 ± 2.003
2.948AspLys: 2.948 ± 1.067
4.127AspLeu: 4.127 ± 5.182
0.59AspMet: 0.59 ± 0.407
3.538AspAsn: 3.538 ± 1.818
2.358AspPro: 2.358 ± 1.628
1.769AspGln: 1.769 ± 0.818
2.948AspArg: 2.948 ± 1.466
3.538AspSer: 3.538 ± 1.736
2.948AspThr: 2.948 ± 0.513
5.896AspVal: 5.896 ± 2.045
0.0AspTrp: 0.0 ± 0.0
2.948AspTyr: 2.948 ± 1.066
0.0AspXaa: 0.0 ± 0.0
Glu
3.538GluAla: 3.538 ± 0.62
0.59GluCys: 0.59 ± 0.407
5.896GluAsp: 5.896 ± 2.045
5.896GluGlu: 5.896 ± 2.51
2.948GluPhe: 2.948 ± 2.77
3.538GluGly: 3.538 ± 0.866
1.769GluHis: 1.769 ± 0.818
1.769GluIle: 1.769 ± 0.818
6.486GluLys: 6.486 ± 2.446
4.717GluLeu: 4.717 ± 1.376
0.59GluMet: 0.59 ± 0.407
2.948GluAsn: 2.948 ± 1.236
2.948GluPro: 2.948 ± 0.713
4.127GluGln: 4.127 ± 0.832
3.538GluArg: 3.538 ± 1.349
3.538GluSer: 3.538 ± 1.443
3.538GluThr: 3.538 ± 2.372
7.665GluVal: 7.665 ± 2.84
1.769GluTrp: 1.769 ± 1.392
1.769GluTyr: 1.769 ± 0.721
0.0GluXaa: 0.0 ± 0.0
Phe
1.179PheAla: 1.179 ± 0.814
1.769PheCys: 1.769 ± 2.746
2.948PheAsp: 2.948 ± 1.368
3.538PheGlu: 3.538 ± 1.637
0.59PhePhe: 0.59 ± 0.407
4.127PheGly: 4.127 ± 0.855
0.59PheHis: 0.59 ± 0.464
1.769PheIle: 1.769 ± 1.221
3.538PheLys: 3.538 ± 0.62
3.538PheLeu: 3.538 ± 2.377
1.179PheMet: 1.179 ± 0.814
2.358PheAsn: 2.358 ± 1.031
1.769PhePro: 1.769 ± 0.764
2.358PheGln: 2.358 ± 2.168
1.769PheArg: 1.769 ± 0.721
1.179PheSer: 1.179 ± 0.45
3.538PheThr: 3.538 ± 2.582
0.59PheVal: 0.59 ± 0.464
0.0PheTrp: 0.0 ± 0.0
0.59PheTyr: 0.59 ± 0.464
0.0PheXaa: 0.0 ± 0.0
Gly
7.075GlyAla: 7.075 ± 2.405
1.179GlyCys: 1.179 ± 2.715
4.127GlyAsp: 4.127 ± 1.101
4.717GlyGlu: 4.717 ± 1.196
5.307GlyPhe: 5.307 ± 1.469
7.665GlyGly: 7.665 ± 2.582
0.59GlyHis: 0.59 ± 0.788
4.717GlyIle: 4.717 ± 1.736
3.538GlyLys: 3.538 ± 2.593
6.486GlyLeu: 6.486 ± 1.28
1.769GlyMet: 1.769 ± 1.007
1.179GlyAsn: 1.179 ± 0.814
5.896GlyPro: 5.896 ± 2.738
1.769GlyGln: 1.769 ± 2.746
2.948GlyArg: 2.948 ± 1.702
4.717GlySer: 4.717 ± 2.958
2.948GlyThr: 2.948 ± 1.236
4.127GlyVal: 4.127 ± 1.939
1.179GlyTrp: 1.179 ± 0.814
2.948GlyTyr: 2.948 ± 2.831
0.0GlyXaa: 0.0 ± 0.0
His
1.769HisAla: 1.769 ± 0.721
0.0HisCys: 0.0 ± 0.0
1.179HisAsp: 1.179 ± 1.575
0.59HisGlu: 0.59 ± 0.464
0.59HisPhe: 0.59 ± 0.407
0.59HisGly: 0.59 ± 0.464
0.0HisHis: 0.0 ± 0.0
0.59HisIle: 0.59 ± 0.788
0.59HisLys: 0.59 ± 0.407
1.179HisLeu: 1.179 ± 0.45
0.0HisMet: 0.0 ± 0.0
0.59HisAsn: 0.59 ± 0.407
1.769HisPro: 1.769 ± 1.392
2.948HisGln: 2.948 ± 1.236
1.179HisArg: 1.179 ± 0.928
2.358HisSer: 2.358 ± 1.363
1.179HisThr: 1.179 ± 0.814
1.769HisVal: 1.769 ± 5.562
1.179HisTrp: 1.179 ± 0.45
1.179HisTyr: 1.179 ± 0.928
0.0HisXaa: 0.0 ± 0.0
Ile
3.538IleAla: 3.538 ± 1.349
0.0IleCys: 0.0 ± 0.0
1.769IleAsp: 1.769 ± 0.721
4.127IleGlu: 4.127 ± 0.832
0.59IlePhe: 0.59 ± 0.407
3.538IleGly: 3.538 ± 2.158
1.179IleHis: 1.179 ± 0.45
0.59IleIle: 0.59 ± 0.407
2.948IleLys: 2.948 ± 1.066
1.179IleLeu: 1.179 ± 0.45
0.59IleMet: 0.59 ± 0.464
0.59IleAsn: 0.59 ± 0.464
5.896IlePro: 5.896 ± 1.468
1.179IleGln: 1.179 ± 0.45
2.358IleArg: 2.358 ± 1.252
1.769IleSer: 1.769 ± 0.49
1.179IleThr: 1.179 ± 0.814
2.358IleVal: 2.358 ± 1.552
1.769IleTrp: 1.769 ± 0.49
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.307LysAla: 5.307 ± 1.235
0.59LysCys: 0.59 ± 0.407
4.127LysAsp: 4.127 ± 0.832
4.127LysGlu: 4.127 ± 1.793
1.179LysPhe: 1.179 ± 0.45
4.717LysGly: 4.717 ± 2.406
1.769LysHis: 1.769 ± 0.818
1.769LysIle: 1.769 ± 2.363
5.896LysLys: 5.896 ± 2.045
4.127LysLeu: 4.127 ± 1.701
3.538LysMet: 3.538 ± 0.749
1.179LysAsn: 1.179 ± 0.928
1.179LysPro: 1.179 ± 0.776
1.179LysGln: 1.179 ± 0.661
4.717LysArg: 4.717 ± 2.866
3.538LysSer: 3.538 ± 1.067
0.59LysThr: 0.59 ± 0.407
4.127LysVal: 4.127 ± 1.793
1.179LysTrp: 1.179 ± 0.45
1.179LysTyr: 1.179 ± 0.661
0.0LysXaa: 0.0 ± 0.0
Leu
7.075LeuAla: 7.075 ± 2.698
0.59LeuCys: 0.59 ± 0.407
5.896LeuAsp: 5.896 ± 1.397
5.307LeuGlu: 5.307 ± 2.003
5.896LeuPhe: 5.896 ± 1.316
4.127LeuGly: 4.127 ± 0.855
0.0LeuHis: 0.0 ± 0.0
2.948LeuIle: 2.948 ± 0.513
2.358LeuLys: 2.358 ± 0.899
8.255LeuLeu: 8.255 ± 3.092
3.538LeuMet: 3.538 ± 2.706
4.717LeuAsn: 4.717 ± 4.356
4.127LeuPro: 4.127 ± 1.17
2.948LeuGln: 2.948 ± 2.859
5.307LeuArg: 5.307 ± 2.09
5.896LeuSer: 5.896 ± 1.027
5.307LeuThr: 5.307 ± 2.414
2.948LeuVal: 2.948 ± 1.067
1.769LeuTrp: 1.769 ± 1.221
1.179LeuTyr: 1.179 ± 0.661
0.0LeuXaa: 0.0 ± 0.0
Met
4.717MetAla: 4.717 ± 0.983
1.179MetCys: 1.179 ± 0.661
3.538MetAsp: 3.538 ± 1.982
2.948MetGlu: 2.948 ± 2.831
0.59MetPhe: 0.59 ± 0.788
2.358MetGly: 2.358 ± 1.252
0.0MetHis: 0.0 ± 0.0
1.769MetIle: 1.769 ± 0.721
1.179MetLys: 1.179 ± 0.661
2.948MetLeu: 2.948 ± 1.066
1.179MetMet: 1.179 ± 0.661
0.59MetAsn: 0.59 ± 0.788
1.769MetPro: 1.769 ± 2.363
0.59MetGln: 0.59 ± 0.407
1.179MetArg: 1.179 ± 0.814
1.769MetSer: 1.769 ± 2.672
1.179MetThr: 1.179 ± 0.776
0.59MetVal: 0.59 ± 0.407
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.717AsnAla: 4.717 ± 0.983
0.59AsnCys: 0.59 ± 0.407
2.358AsnAsp: 2.358 ± 1.252
0.0AsnGlu: 0.0 ± 0.0
0.59AsnPhe: 0.59 ± 0.407
3.538AsnGly: 3.538 ± 0.979
0.0AsnHis: 0.0 ± 0.0
1.179AsnIle: 1.179 ± 0.928
4.717AsnLys: 4.717 ± 2.117
1.769AsnLeu: 1.769 ± 0.721
2.358AsnMet: 2.358 ± 1.628
1.179AsnAsn: 1.179 ± 0.661
1.769AsnPro: 1.769 ± 1.493
2.358AsnGln: 2.358 ± 0.688
0.59AsnArg: 0.59 ± 0.407
3.538AsnSer: 3.538 ± 1.982
2.948AsnThr: 2.948 ± 0.513
2.948AsnVal: 2.948 ± 2.831
0.0AsnTrp: 0.0 ± 0.0
0.59AsnTyr: 0.59 ± 0.407
0.0AsnXaa: 0.0 ± 0.0
Pro
3.538ProAla: 3.538 ± 0.866
1.179ProCys: 1.179 ± 0.814
3.538ProAsp: 3.538 ± 1.861
3.538ProGlu: 3.538 ± 1.043
4.717ProPhe: 4.717 ± 1.843
3.538ProGly: 3.538 ± 1.528
0.59ProHis: 0.59 ± 0.788
1.179ProIle: 1.179 ± 0.928
1.769ProLys: 1.769 ± 1.221
2.358ProLeu: 2.358 ± 1.321
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
7.075ProPro: 7.075 ± 5.223
4.127ProGln: 4.127 ± 2.707
4.717ProArg: 4.717 ± 1.685
2.358ProSer: 2.358 ± 1.321
1.179ProThr: 1.179 ± 2.907
5.896ProVal: 5.896 ± 2.198
1.769ProTrp: 1.769 ± 2.746
1.769ProTyr: 1.769 ± 0.764
0.0ProXaa: 0.0 ± 0.0
Gln
4.127GlnAla: 4.127 ± 1.677
1.179GlnCys: 1.179 ± 0.814
2.948GlnAsp: 2.948 ± 1.232
0.59GlnGlu: 0.59 ± 0.407
2.358GlnPhe: 2.358 ± 2.799
4.127GlnGly: 4.127 ± 1.17
0.0GlnHis: 0.0 ± 0.0
0.59GlnIle: 0.59 ± 0.407
1.179GlnLys: 1.179 ± 0.45
4.717GlnLeu: 4.717 ± 1.707
1.179GlnMet: 1.179 ± 1.575
1.179GlnAsn: 1.179 ± 0.814
2.948GlnPro: 2.948 ± 6.057
2.358GlnGln: 2.358 ± 1.321
1.769GlnArg: 1.769 ± 1.007
2.358GlnSer: 2.358 ± 0.456
2.948GlnThr: 2.948 ± 1.067
1.769GlnVal: 1.769 ± 0.721
0.59GlnTrp: 0.59 ± 0.788
1.179GlnTyr: 1.179 ± 0.661
0.0GlnXaa: 0.0 ± 0.0
Arg
4.127ArgAla: 4.127 ± 1.563
1.179ArgCys: 1.179 ± 2.715
1.769ArgAsp: 1.769 ± 0.818
5.307ArgGlu: 5.307 ± 2.112
1.179ArgPhe: 1.179 ± 0.814
3.538ArgGly: 3.538 ± 0.866
4.127ArgHis: 4.127 ± 2.705
2.948ArgIle: 2.948 ± 0.513
4.127ArgLys: 4.127 ± 2.064
5.896ArgLeu: 5.896 ± 2.472
0.59ArgMet: 0.59 ± 0.407
1.769ArgAsn: 1.769 ± 0.721
0.0ArgPro: 0.0 ± 0.0
1.179ArgGln: 1.179 ± 0.661
5.896ArgArg: 5.896 ± 2.879
1.769ArgSer: 1.769 ± 1.392
1.179ArgThr: 1.179 ± 0.928
1.769ArgVal: 1.769 ± 0.49
1.179ArgTrp: 1.179 ± 1.575
3.538ArgTyr: 3.538 ± 0.62
0.0ArgXaa: 0.0 ± 0.0
Ser
6.486SerAla: 6.486 ± 1.994
1.179SerCys: 1.179 ± 2.715
3.538SerAsp: 3.538 ± 1.861
3.538SerGlu: 3.538 ± 2.377
1.769SerPhe: 1.769 ± 0.721
6.486SerGly: 6.486 ± 3.674
0.59SerHis: 0.59 ± 0.407
0.0SerIle: 0.0 ± 0.0
4.127SerLys: 4.127 ± 0.915
3.538SerLeu: 3.538 ± 2.606
2.358SerMet: 2.358 ± 1.3
4.717SerAsn: 4.717 ± 0.913
1.769SerPro: 1.769 ± 0.764
2.948SerGln: 2.948 ± 1.066
1.179SerArg: 1.179 ± 0.928
8.844SerSer: 8.844 ± 5.02
4.127SerThr: 4.127 ± 0.855
5.307SerVal: 5.307 ± 2.24
1.769SerTrp: 1.769 ± 1.007
1.179SerTyr: 1.179 ± 0.776
0.0SerXaa: 0.0 ± 0.0
Thr
7.075ThrAla: 7.075 ± 3.565
0.59ThrCys: 0.59 ± 0.407
3.538ThrAsp: 3.538 ± 1.443
5.896ThrGlu: 5.896 ± 2.638
1.179ThrPhe: 1.179 ± 0.45
5.307ThrGly: 5.307 ± 3.286
0.0ThrHis: 0.0 ± 0.0
0.59ThrIle: 0.59 ± 0.788
0.0ThrLys: 0.0 ± 0.0
3.538ThrLeu: 3.538 ± 1.396
2.358ThrMet: 2.358 ± 1.264
4.127ThrAsn: 4.127 ± 1.563
2.948ThrPro: 2.948 ± 1.466
2.358ThrGln: 2.358 ± 0.456
2.358ThrArg: 2.358 ± 0.688
4.717ThrSer: 4.717 ± 2.383
4.127ThrThr: 4.127 ± 0.915
2.948ThrVal: 2.948 ± 0.513
0.59ThrTrp: 0.59 ± 0.407
0.59ThrTyr: 0.59 ± 0.407
0.0ThrXaa: 0.0 ± 0.0
Val
7.075ValAla: 7.075 ± 1.307
1.179ValCys: 1.179 ± 0.814
4.127ValAsp: 4.127 ± 5.163
3.538ValGlu: 3.538 ± 1.043
1.179ValPhe: 1.179 ± 0.45
5.307ValGly: 5.307 ± 3.128
2.948ValHis: 2.948 ± 2.694
2.358ValIle: 2.358 ± 0.899
3.538ValLys: 3.538 ± 2.627
8.844ValLeu: 8.844 ± 1.841
2.358ValMet: 2.358 ± 2.168
2.948ValAsn: 2.948 ± 0.513
2.358ValPro: 2.358 ± 0.899
2.948ValGln: 2.948 ± 1.066
1.179ValArg: 1.179 ± 0.45
4.717ValSer: 4.717 ± 0.913
4.127ValThr: 4.127 ± 0.832
5.896ValVal: 5.896 ± 1.468
1.179ValTrp: 1.179 ± 0.814
1.179ValTyr: 1.179 ± 0.814
0.0ValXaa: 0.0 ± 0.0
Trp
0.59TrpAla: 0.59 ± 0.788
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.179TrpGlu: 1.179 ± 0.776
0.0TrpPhe: 0.0 ± 0.0
1.769TrpGly: 1.769 ± 2.746
0.0TrpHis: 0.0 ± 0.0
1.179TrpIle: 1.179 ± 0.45
0.59TrpLys: 0.59 ± 0.407
2.358TrpLeu: 2.358 ± 0.688
0.59TrpMet: 0.59 ± 0.788
1.179TrpAsn: 1.179 ± 0.814
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.358TrpArg: 2.358 ± 1.252
0.59TrpSer: 0.59 ± 0.407
0.59TrpThr: 0.59 ± 0.407
2.358TrpVal: 2.358 ± 1.031
0.0TrpTrp: 0.0 ± 0.0
1.179TrpTyr: 1.179 ± 0.776
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.179TyrAla: 1.179 ± 0.814
0.0TyrCys: 0.0 ± 0.0
1.179TyrAsp: 1.179 ± 0.45
0.59TyrGlu: 0.59 ± 0.788
1.179TyrPhe: 1.179 ± 0.661
0.59TyrGly: 0.59 ± 0.407
2.358TyrHis: 2.358 ± 1.252
1.179TyrIle: 1.179 ± 0.814
0.0TyrLys: 0.0 ± 0.0
3.538TyrLeu: 3.538 ± 0.979
1.179TyrMet: 1.179 ± 0.661
1.769TyrAsn: 1.769 ± 1.396
1.769TyrPro: 1.769 ± 0.721
2.358TyrGln: 2.358 ± 2.991
2.358TyrArg: 2.358 ± 0.899
0.59TyrSer: 0.59 ± 0.788
1.179TyrThr: 1.179 ± 0.45
1.769TyrVal: 1.769 ± 1.396
0.0TyrTrp: 0.0 ± 0.0
1.179TyrTyr: 1.179 ± 0.661
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1697 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski