Amino acid dipepetide frequency for Tamlana carrageenivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.259AlaAla: 4.259 ± 0.089	0.674AlaCys: 0.674 ± 0.029	3.365AlaAsp: 3.365 ± 0.062	4.12AlaGlu: 4.12 ± 0.074	3.488AlaPhe: 3.488 ± 0.047	3.956AlaGly: 3.956 ± 0.08	1.288AlaHis: 1.288 ± 0.037	5.325AlaIle: 5.325 ± 0.078	4.993AlaLys: 4.993 ± 0.07	6.633AlaLeu: 6.633 ± 0.079	1.494AlaMet: 1.494 ± 0.04	3.516AlaAsn: 3.516 ± 0.06	1.981AlaPro: 1.981 ± 0.053	2.532AlaGln: 2.532 ± 0.05	2.025AlaArg: 2.025 ± 0.047	4.431AlaSer: 4.431 ± 0.083	3.745AlaThr: 3.745 ± 0.098	4.233AlaVal: 4.233 ± 0.064	0.679AlaTrp: 0.679 ± 0.027	2.645AlaTyr: 2.645 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.49CysAla: 0.49 ± 0.027	0.118CysCys: 0.118 ± 0.01	0.496CysAsp: 0.496 ± 0.022	0.501CysGlu: 0.501 ± 0.024	0.447CysPhe: 0.447 ± 0.019	0.6CysGly: 0.6 ± 0.026	0.222CysHis: 0.222 ± 0.018	0.613CysIle: 0.613 ± 0.025	0.553CysLys: 0.553 ± 0.023	0.677CysLeu: 0.677 ± 0.027	0.186CysMet: 0.186 ± 0.013	0.417CysAsn: 0.417 ± 0.022	0.31CysPro: 0.31 ± 0.02	0.237CysGln: 0.237 ± 0.013	0.211CysArg: 0.211 ± 0.014	0.579CysSer: 0.579 ± 0.027	0.445CysThr: 0.445 ± 0.024	0.485CysVal: 0.485 ± 0.022	0.101CysTrp: 0.101 ± 0.015	0.348CysTyr: 0.348 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.047AspAla: 4.047 ± 0.072	0.447AspCys: 0.447 ± 0.022	3.155AspAsp: 3.155 ± 0.059	3.649AspGlu: 3.649 ± 0.058	3.707AspPhe: 3.707 ± 0.066	3.646AspGly: 3.646 ± 0.077	1.015AspHis: 1.015 ± 0.033	4.606AspIle: 4.606 ± 0.069	4.151AspLys: 4.151 ± 0.07	5.499AspLeu: 5.499 ± 0.08	1.218AspMet: 1.218 ± 0.037	3.041AspAsn: 3.041 ± 0.055	1.712AspPro: 1.712 ± 0.05	1.499AspGln: 1.499 ± 0.038	1.937AspArg: 1.937 ± 0.045	3.139AspSer: 3.139 ± 0.055	2.766AspThr: 2.766 ± 0.053	3.874AspVal: 3.874 ± 0.06	0.785AspTrp: 0.785 ± 0.03	2.931AspTyr: 2.931 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	5.066GluAla: 5.066 ± 0.072	0.332GluCys: 0.332 ± 0.021	3.753GluAsp: 3.753 ± 0.055	4.249GluGlu: 4.249 ± 0.067	2.881GluPhe: 2.881 ± 0.054	3.702GluGly: 3.702 ± 0.058	1.287GluHis: 1.287 ± 0.037	5.093GluIle: 5.093 ± 0.085	5.249GluLys: 5.249 ± 0.087	5.825GluLeu: 5.825 ± 0.079	1.344GluMet: 1.344 ± 0.034	4.658GluAsn: 4.658 ± 0.065	1.655GluPro: 1.655 ± 0.04	2.28GluGln: 2.28 ± 0.049	2.428GluArg: 2.428 ± 0.054	3.545GluSer: 3.545 ± 0.056	3.901GluThr: 3.901 ± 0.063	4.512GluVal: 4.512 ± 0.066	0.541GluTrp: 0.541 ± 0.023	2.193GluTyr: 2.193 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	2.793PheAla: 2.793 ± 0.052	0.465PheCys: 0.465 ± 0.02	3.202PheAsp: 3.202 ± 0.06	3.401PheGlu: 3.401 ± 0.063	2.449PhePhe: 2.449 ± 0.058	3.429PheGly: 3.429 ± 0.06	0.859PheHis: 0.859 ± 0.027	3.85PheIle: 3.85 ± 0.068	4.151PheLys: 4.151 ± 0.074	4.595PheLeu: 4.595 ± 0.081	1.1PheMet: 1.1 ± 0.03	3.382PheAsn: 3.382 ± 0.067	1.692PhePro: 1.692 ± 0.036	1.546PheGln: 1.546 ± 0.037	1.556PheArg: 1.556 ± 0.037	3.903PheSer: 3.903 ± 0.069	2.918PheThr: 2.918 ± 0.059	2.971PheVal: 2.971 ± 0.052	0.603PheTrp: 0.603 ± 0.025	2.06PheTyr: 2.06 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.256GlyAla: 4.256 ± 0.072	0.606GlyCys: 0.606 ± 0.042	3.553GlyAsp: 3.553 ± 0.058	3.549GlyGlu: 3.549 ± 0.059	3.558GlyPhe: 3.558 ± 0.063	4.528GlyGly: 4.528 ± 0.096	1.237GlyHis: 1.237 ± 0.035	4.98GlyIle: 4.98 ± 0.084	4.784GlyLys: 4.784 ± 0.077	5.679GlyLeu: 5.679 ± 0.078	1.546GlyMet: 1.546 ± 0.046	3.391GlyAsn: 3.391 ± 0.063	1.308GlyPro: 1.308 ± 0.04	1.91GlyGln: 1.91 ± 0.056	2.181GlyArg: 2.181 ± 0.046	3.931GlySer: 3.931 ± 0.083	3.854GlyThr: 3.854 ± 0.086	4.735GlyVal: 4.735 ± 0.075	0.788GlyTrp: 0.788 ± 0.029	2.857GlyTyr: 2.857 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.172HisAla: 1.172 ± 0.032	0.178HisCys: 0.178 ± 0.012	1.024HisAsp: 1.024 ± 0.034	1.141HisGlu: 1.141 ± 0.033	1.227HisPhe: 1.227 ± 0.04	1.225HisGly: 1.225 ± 0.031	0.515HisHis: 0.515 ± 0.025	1.667HisIle: 1.667 ± 0.044	1.311HisLys: 1.311 ± 0.036	1.97HisLeu: 1.97 ± 0.047	0.358HisMet: 0.358 ± 0.017	1.071HisAsn: 1.071 ± 0.028	0.865HisPro: 0.865 ± 0.027	0.802HisGln: 0.802 ± 0.03	0.659HisArg: 0.659 ± 0.025	1.082HisSer: 1.082 ± 0.034	1.046HisThr: 1.046 ± 0.031	1.156HisVal: 1.156 ± 0.032	0.253HisTrp: 0.253 ± 0.015	0.944HisTyr: 0.944 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.311IleAla: 5.311 ± 0.079	0.63IleCys: 0.63 ± 0.024	4.896IleAsp: 4.896 ± 0.067	5.455IleGlu: 5.455 ± 0.083	3.32IlePhe: 3.32 ± 0.07	4.898IleGly: 4.898 ± 0.083	1.41IleHis: 1.41 ± 0.039	5.937IleIle: 5.937 ± 0.09	6.176IleLys: 6.176 ± 0.081	6.511IleLeu: 6.511 ± 0.107	1.463IleMet: 1.463 ± 0.038	4.801IleAsn: 4.801 ± 0.072	3.128IlePro: 3.128 ± 0.051	2.567IleGln: 2.567 ± 0.051	2.532IleArg: 2.532 ± 0.056	5.601IleSer: 5.601 ± 0.077	4.825IleThr: 4.825 ± 0.08	4.479IleVal: 4.479 ± 0.068	0.703IleTrp: 0.703 ± 0.026	2.754IleTyr: 2.754 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	5.545LysAla: 5.545 ± 0.071	0.359LysCys: 0.359 ± 0.018	4.493LysAsp: 4.493 ± 0.065	5.491LysGlu: 5.491 ± 0.083	2.952LysPhe: 2.952 ± 0.061	4.771LysGly: 4.771 ± 0.066	1.736LysHis: 1.736 ± 0.043	6.014LysIle: 6.014 ± 0.08	6.599LysLys: 6.599 ± 0.111	6.822LysLeu: 6.822 ± 0.094	1.906LysMet: 1.906 ± 0.044	5.366LysAsn: 5.366 ± 0.083	2.563LysPro: 2.563 ± 0.055	3.005LysGln: 3.005 ± 0.067	3.14LysArg: 3.14 ± 0.058	4.911LysSer: 4.911 ± 0.07	5.029LysThr: 5.029 ± 0.071	4.7LysVal: 4.7 ± 0.076	0.805LysTrp: 0.805 ± 0.031	2.977LysTyr: 2.977 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	5.668LeuAla: 5.668 ± 0.082	0.759LeuCys: 0.759 ± 0.025	5.143LeuAsp: 5.143 ± 0.073	6.267LeuGlu: 6.267 ± 0.08	4.714LeuPhe: 4.714 ± 0.074	5.702LeuGly: 5.702 ± 0.073	1.617LeuHis: 1.617 ± 0.04	6.698LeuIle: 6.698 ± 0.079	8.32LeuLys: 8.32 ± 0.104	8.203LeuLeu: 8.203 ± 0.114	1.94LeuMet: 1.94 ± 0.044	5.994LeuAsn: 5.994 ± 0.087	3.385LeuPro: 3.385 ± 0.057	3.129LeuGln: 3.129 ± 0.052	3.164LeuArg: 3.164 ± 0.054	6.561LeuSer: 6.561 ± 0.087	5.091LeuThr: 5.091 ± 0.067	5.425LeuVal: 5.425 ± 0.074	0.827LeuTrp: 0.827 ± 0.03	3.145LeuTyr: 3.145 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	1.698MetAla: 1.698 ± 0.049	0.151MetCys: 0.151 ± 0.011	1.076MetAsp: 1.076 ± 0.031	1.21MetGlu: 1.21 ± 0.035	0.928MetPhe: 0.928 ± 0.029	1.314MetGly: 1.314 ± 0.035	0.416MetHis: 0.416 ± 0.018	1.461MetIle: 1.461 ± 0.035	1.976MetLys: 1.976 ± 0.045	1.911MetLeu: 1.911 ± 0.044	0.546MetMet: 0.546 ± 0.022	1.205MetAsn: 1.205 ± 0.032	0.875MetPro: 0.875 ± 0.026	0.81MetGln: 0.81 ± 0.028	0.866MetArg: 0.866 ± 0.028	1.412MetSer: 1.412 ± 0.037	1.238MetThr: 1.238 ± 0.034	1.372MetVal: 1.372 ± 0.034	0.166MetTrp: 0.166 ± 0.011	0.698MetTyr: 0.698 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.919AsnAla: 3.919 ± 0.063	0.472AsnCys: 0.472 ± 0.023	3.289AsnAsp: 3.289 ± 0.056	3.521AsnGlu: 3.521 ± 0.061	2.911AsnPhe: 2.911 ± 0.062	3.932AsnGly: 3.932 ± 0.079	1.352AsnHis: 1.352 ± 0.04	4.863AsnIle: 4.863 ± 0.07	4.643AsnLys: 4.643 ± 0.077	5.471AsnLeu: 5.471 ± 0.08	1.291AsnMet: 1.291 ± 0.032	4.0AsnAsn: 4.0 ± 0.081	2.714AsnPro: 2.714 ± 0.052	2.407AsnGln: 2.407 ± 0.052	2.324AsnArg: 2.324 ± 0.045	3.833AsnSer: 3.833 ± 0.065	3.874AsnThr: 3.874 ± 0.071	3.367AsnVal: 3.367 ± 0.069	0.788AsnTrp: 0.788 ± 0.025	2.973AsnTyr: 2.973 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	1.824ProAla: 1.824 ± 0.044	0.243ProCys: 0.243 ± 0.015	1.967ProAsp: 1.967 ± 0.049	3.0ProGlu: 3.0 ± 0.053	1.872ProPhe: 1.872 ± 0.048	1.863ProGly: 1.863 ± 0.048	0.666ProHis: 0.666 ± 0.03	2.618ProIle: 2.618 ± 0.049	2.697ProLys: 2.697 ± 0.048	2.999ProLeu: 2.999 ± 0.053	0.731ProMet: 0.731 ± 0.029	2.284ProAsn: 2.284 ± 0.054	0.756ProPro: 0.756 ± 0.029	1.086ProGln: 1.086 ± 0.028	0.916ProArg: 0.916 ± 0.028	2.169ProSer: 2.169 ± 0.054	1.913ProThr: 1.913 ± 0.053	2.25ProVal: 2.25 ± 0.049	0.346ProTrp: 0.346 ± 0.017	1.407ProTyr: 1.407 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.246GlnAla: 2.246 ± 0.048	0.197GlnCys: 0.197 ± 0.014	1.806GlnAsp: 1.806 ± 0.041	2.213GlnGlu: 2.213 ± 0.048	1.687GlnPhe: 1.687 ± 0.042	1.939GlnGly: 1.939 ± 0.042	0.655GlnHis: 0.655 ± 0.025	2.748GlnIle: 2.748 ± 0.046	2.79GlnLys: 2.79 ± 0.059	3.46GlnLeu: 3.46 ± 0.066	0.735GlnMet: 0.735 ± 0.025	2.161GlnAsn: 2.161 ± 0.046	1.167GlnPro: 1.167 ± 0.042	1.341GlnGln: 1.341 ± 0.041	1.282GlnArg: 1.282 ± 0.038	1.955GlnSer: 1.955 ± 0.037	1.866GlnThr: 1.866 ± 0.045	2.126GlnVal: 2.126 ± 0.048	0.392GlnTrp: 0.392 ± 0.018	1.426GlnTyr: 1.426 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.15ArgAla: 2.15 ± 0.053	0.213ArgCys: 0.213 ± 0.013	1.882ArgAsp: 1.882 ± 0.045	2.08ArgGlu: 2.08 ± 0.051	1.898ArgPhe: 1.898 ± 0.045	2.052ArgGly: 2.052 ± 0.048	0.698ArgHis: 0.698 ± 0.027	2.793ArgIle: 2.793 ± 0.058	2.741ArgLys: 2.741 ± 0.054	3.38ArgLeu: 3.38 ± 0.071	0.795ArgMet: 0.795 ± 0.027	2.016ArgAsn: 2.016 ± 0.042	1.115ArgPro: 1.115 ± 0.035	1.161ArgGln: 1.161 ± 0.03	1.467ArgArg: 1.467 ± 0.041	2.005ArgSer: 2.005 ± 0.048	1.815ArgThr: 1.815 ± 0.04	2.175ArgVal: 2.175 ± 0.051	0.461ArgTrp: 0.461 ± 0.019	1.606ArgTyr: 1.606 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	3.868SerAla: 3.868 ± 0.083	0.7SerCys: 0.7 ± 0.033	3.646SerAsp: 3.646 ± 0.059	4.233SerGlu: 4.233 ± 0.057	3.571SerPhe: 3.571 ± 0.056	4.622SerGly: 4.622 ± 0.093	1.211SerHis: 1.211 ± 0.033	4.992SerIle: 4.992 ± 0.074	5.216SerLys: 5.216 ± 0.078	5.811SerLeu: 5.811 ± 0.07	1.276SerMet: 1.276 ± 0.032	3.985SerAsn: 3.985 ± 0.079	1.94SerPro: 1.94 ± 0.042	2.157SerGln: 2.157 ± 0.047	2.115SerArg: 2.115 ± 0.047	4.153SerSer: 4.153 ± 0.068	3.541SerThr: 3.541 ± 0.069	4.005SerVal: 4.005 ± 0.054	0.766SerTrp: 0.766 ± 0.029	2.77SerTyr: 2.77 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	3.782ThrAla: 3.782 ± 0.082	0.445ThrCys: 0.445 ± 0.025	3.273ThrAsp: 3.273 ± 0.064	3.373ThrGlu: 3.373 ± 0.06	2.972ThrPhe: 2.972 ± 0.053	4.001ThrGly: 4.001 ± 0.082	1.132ThrHis: 1.132 ± 0.032	4.738ThrIle: 4.738 ± 0.081	3.955ThrLys: 3.955 ± 0.058	5.503ThrLeu: 5.503 ± 0.072	1.056ThrMet: 1.056 ± 0.029	3.494ThrAsn: 3.494 ± 0.066	2.566ThrPro: 2.566 ± 0.062	1.872ThrGln: 1.872 ± 0.047	1.721ThrArg: 1.721 ± 0.044	3.783ThrSer: 3.783 ± 0.066	3.595ThrThr: 3.595 ± 0.083	3.73ThrVal: 3.73 ± 0.075	0.613ThrTrp: 0.613 ± 0.024	2.489ThrTyr: 2.489 ± 0.056	0.0ThrXaa: 0.0 ± 0.0
Val	4.101ValAla: 4.101 ± 0.069	0.588ValCys: 0.588 ± 0.026	3.715ValAsp: 3.715 ± 0.063	3.996ValGlu: 3.996 ± 0.061	3.382ValPhe: 3.382 ± 0.052	3.796ValGly: 3.796 ± 0.072	1.125ValHis: 1.125 ± 0.028	4.966ValIle: 4.966 ± 0.076	4.744ValLys: 4.744 ± 0.077	6.108ValLeu: 6.108 ± 0.081	1.283ValMet: 1.283 ± 0.039	3.688ValAsn: 3.688 ± 0.059	2.105ValPro: 2.105 ± 0.044	1.759ValGln: 1.759 ± 0.037	1.998ValArg: 1.998 ± 0.049	4.517ValSer: 4.517 ± 0.071	3.565ValThr: 3.565 ± 0.078	4.403ValVal: 4.403 ± 0.071	0.615ValTrp: 0.615 ± 0.028	2.487ValTyr: 2.487 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.644TrpAla: 0.644 ± 0.028	0.111TrpCys: 0.111 ± 0.009	0.704TrpAsp: 0.704 ± 0.026	0.718TrpGlu: 0.718 ± 0.03	0.531TrpPhe: 0.531 ± 0.024	0.692TrpGly: 0.692 ± 0.029	0.289TrpHis: 0.289 ± 0.015	0.7TrpIle: 0.7 ± 0.029	0.792TrpLys: 0.792 ± 0.03	0.987TrpLeu: 0.987 ± 0.032	0.321TrpMet: 0.321 ± 0.018	0.683TrpAsn: 0.683 ± 0.025	0.251TrpPro: 0.251 ± 0.015	0.477TrpGln: 0.477 ± 0.023	0.384TrpArg: 0.384 ± 0.018	0.647TrpSer: 0.647 ± 0.03	0.632TrpThr: 0.632 ± 0.026	0.652TrpVal: 0.652 ± 0.026	0.155TrpTrp: 0.155 ± 0.012	0.499TrpTyr: 0.499 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.542TyrAla: 2.542 ± 0.05	0.349TyrCys: 0.349 ± 0.016	2.387TyrAsp: 2.387 ± 0.048	2.327TyrGlu: 2.327 ± 0.046	2.429TyrPhe: 2.429 ± 0.053	2.562TyrGly: 2.562 ± 0.051	0.936TyrHis: 0.936 ± 0.031	2.736TyrIle: 2.736 ± 0.046	3.343TyrLys: 3.343 ± 0.058	3.707TyrLeu: 3.707 ± 0.057	0.738TyrMet: 0.738 ± 0.029	2.792TyrAsn: 2.792 ± 0.055	1.52TyrPro: 1.52 ± 0.04	1.614TyrGln: 1.614 ± 0.038	1.595TyrArg: 1.595 ± 0.038	2.422TyrSer: 2.422 ± 0.055	2.435TyrThr: 2.435 ± 0.058	2.292TyrVal: 2.292 ± 0.049	0.481TyrTrp: 0.481 ± 0.021	1.844TyrTyr: 1.844 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3310 proteins (1129353 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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