Amino acid dipepetide frequency for Tortoise microvirus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
1.809AlaCys: 1.809 ± 1.6
7.238AlaAsp: 7.238 ± 1.794
1.206AlaGlu: 1.206 ± 0.697
1.809AlaPhe: 1.809 ± 0.74
4.825AlaGly: 4.825 ± 1.717
0.0AlaHis: 0.0 ± 0.0
2.413AlaIle: 2.413 ± 1.35
3.619AlaLys: 3.619 ± 1.808
5.428AlaLeu: 5.428 ± 2.624
1.206AlaMet: 1.206 ± 1.36
4.825AlaAsn: 4.825 ± 1.032
6.031AlaPro: 6.031 ± 2.099
3.619AlaGln: 3.619 ± 1.891
5.428AlaArg: 5.428 ± 2.105
7.238AlaSer: 7.238 ± 2.792
1.809AlaThr: 1.809 ± 0.766
3.016AlaVal: 3.016 ± 1.238
1.206AlaTrp: 1.206 ± 1.055
4.222AlaTyr: 4.222 ± 1.856
0.0AlaXaa: 0.0 ± 0.0
Cys
1.809CysAla: 1.809 ± 1.246
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.603CysGly: 0.603 ± 0.533
0.603CysHis: 0.603 ± 0.533
2.413CysIle: 2.413 ± 1.751
0.0CysLys: 0.0 ± 0.0
1.206CysLeu: 1.206 ± 0.706
0.603CysMet: 0.603 ± 0.413
1.206CysAsn: 1.206 ± 0.848
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.206CysArg: 1.206 ± 1.067
1.206CysSer: 1.206 ± 1.067
0.603CysThr: 0.603 ± 0.413
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.603CysTyr: 0.603 ± 0.73
0.0CysXaa: 0.0 ± 0.0
Asp
4.825AspAla: 4.825 ± 1.636
1.206AspCys: 1.206 ± 1.46
3.016AspAsp: 3.016 ± 1.677
1.206AspGlu: 1.206 ± 0.827
4.222AspPhe: 4.222 ± 1.254
1.809AspGly: 1.809 ± 0.898
0.603AspHis: 0.603 ± 0.413
7.238AspIle: 7.238 ± 1.6
4.222AspLys: 4.222 ± 1.962
6.031AspLeu: 6.031 ± 1.598
3.016AspMet: 3.016 ± 1.251
5.428AspAsn: 5.428 ± 0.817
1.809AspPro: 1.809 ± 1.432
1.809AspGln: 1.809 ± 0.746
2.413AspArg: 2.413 ± 1.282
4.825AspSer: 4.825 ± 1.986
3.016AspThr: 3.016 ± 1.016
3.619AspVal: 3.619 ± 1.206
0.603AspTrp: 0.603 ± 0.533
4.222AspTyr: 4.222 ± 1.107
0.0AspXaa: 0.0 ± 0.0
Glu
1.809GluAla: 1.809 ± 1.212
0.603GluCys: 0.603 ± 0.773
2.413GluAsp: 2.413 ± 0.994
2.413GluGlu: 2.413 ± 1.717
3.016GluPhe: 3.016 ± 1.446
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
0.603GluIle: 0.603 ± 0.527
2.413GluLys: 2.413 ± 1.198
4.825GluLeu: 4.825 ± 1.437
2.413GluMet: 2.413 ± 1.706
1.809GluAsn: 1.809 ± 0.673
1.809GluPro: 1.809 ± 1.24
1.809GluGln: 1.809 ± 0.937
3.016GluArg: 3.016 ± 1.362
2.413GluSer: 2.413 ± 0.719
4.222GluThr: 4.222 ± 1.797
1.809GluVal: 1.809 ± 0.936
0.603GluTrp: 0.603 ± 0.533
3.619GluTyr: 3.619 ± 1.422
0.0GluXaa: 0.0 ± 0.0
Phe
3.016PheAla: 3.016 ± 0.885
1.206PheCys: 1.206 ± 0.706
2.413PheAsp: 2.413 ± 0.585
3.016PheGlu: 3.016 ± 1.816
3.016PhePhe: 3.016 ± 1.394
6.031PheGly: 6.031 ± 2.172
0.603PheHis: 0.603 ± 0.773
1.809PheIle: 1.809 ± 0.942
1.809PheLys: 1.809 ± 1.128
1.809PheLeu: 1.809 ± 1.206
3.619PheMet: 3.619 ± 1.556
2.413PheAsn: 2.413 ± 0.757
1.206PhePro: 1.206 ± 0.827
1.206PheGln: 1.206 ± 1.393
2.413PheArg: 2.413 ± 0.849
6.031PheSer: 6.031 ± 2.505
3.016PheThr: 3.016 ± 1.408
2.413PheVal: 2.413 ± 1.091
1.206PheTrp: 1.206 ± 0.827
0.603PheTyr: 0.603 ± 0.73
0.0PheXaa: 0.0 ± 0.0
Gly
6.031GlyAla: 6.031 ± 1.666
0.603GlyCys: 0.603 ± 0.533
1.809GlyAsp: 1.809 ± 1.215
1.809GlyGlu: 1.809 ± 0.854
3.016GlyPhe: 3.016 ± 1.381
6.031GlyGly: 6.031 ± 1.611
0.603GlyHis: 0.603 ± 0.413
4.222GlyIle: 4.222 ± 1.422
0.0GlyLys: 0.0 ± 0.0
6.634GlyLeu: 6.634 ± 1.743
0.0GlyMet: 0.0 ± 0.0
1.809GlyAsn: 1.809 ± 0.746
1.206GlyPro: 1.206 ± 0.827
1.206GlyGln: 1.206 ± 0.495
4.825GlyArg: 4.825 ± 1.36
9.65GlySer: 9.65 ± 2.747
4.825GlyThr: 4.825 ± 2.104
6.031GlyVal: 6.031 ± 1.989
0.603GlyTrp: 0.603 ± 0.413
3.619GlyTyr: 3.619 ± 1.082
0.0GlyXaa: 0.0 ± 0.0
His
1.206HisAla: 1.206 ± 0.752
0.0HisCys: 0.0 ± 0.0
1.206HisAsp: 1.206 ± 0.827
0.0HisGlu: 0.0 ± 0.0
2.413HisPhe: 2.413 ± 1.751
0.0HisGly: 0.0 ± 0.0
0.603HisHis: 0.603 ± 1.271
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.206HisLeu: 1.206 ± 1.237
0.0HisMet: 0.0 ± 0.0
1.206HisAsn: 1.206 ± 0.495
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.809HisArg: 1.809 ± 1.206
1.206HisSer: 1.206 ± 1.393
0.603HisThr: 0.603 ± 0.73
1.206HisVal: 1.206 ± 0.848
1.809HisTrp: 1.809 ± 1.24
1.206HisTyr: 1.206 ± 0.495
0.0HisXaa: 0.0 ± 0.0
Ile
4.222IleAla: 4.222 ± 1.287
0.603IleCys: 0.603 ± 0.73
3.619IleAsp: 3.619 ± 1.573
3.619IleGlu: 3.619 ± 1.599
2.413IlePhe: 2.413 ± 1.099
4.825IleGly: 4.825 ± 1.132
0.603IleHis: 0.603 ± 0.73
2.413IleIle: 2.413 ± 1.018
1.809IleLys: 1.809 ± 1.246
2.413IleLeu: 2.413 ± 1.415
1.206IleMet: 1.206 ± 0.724
1.809IleAsn: 1.809 ± 0.742
2.413IlePro: 2.413 ± 1.264
5.428IleGln: 5.428 ± 1.869
4.825IleArg: 4.825 ± 1.491
7.841IleSer: 7.841 ± 3.359
3.619IleThr: 3.619 ± 1.823
2.413IleVal: 2.413 ± 1.425
0.0IleTrp: 0.0 ± 0.0
1.206IleTyr: 1.206 ± 0.496
0.0IleXaa: 0.0 ± 0.0
Lys
4.825LysAla: 4.825 ± 2.153
0.0LysCys: 0.0 ± 0.0
2.413LysAsp: 2.413 ± 1.669
3.016LysGlu: 3.016 ± 2.617
3.016LysPhe: 3.016 ± 1.394
0.603LysGly: 0.603 ± 1.271
1.206LysHis: 1.206 ± 0.706
2.413LysIle: 2.413 ± 0.585
1.809LysLys: 1.809 ± 0.673
4.222LysLeu: 4.222 ± 0.64
1.206LysMet: 1.206 ± 1.343
1.809LysAsn: 1.809 ± 1.123
1.206LysPro: 1.206 ± 0.827
3.016LysGln: 3.016 ± 1.403
4.222LysArg: 4.222 ± 2.686
4.222LysSer: 4.222 ± 1.662
5.428LysThr: 5.428 ± 2.586
4.222LysVal: 4.222 ± 0.966
0.603LysTrp: 0.603 ± 1.271
2.413LysTyr: 2.413 ± 0.899
0.0LysXaa: 0.0 ± 0.0
Leu
4.222LeuAla: 4.222 ± 1.49
0.0LeuCys: 0.0 ± 0.0
6.031LeuAsp: 6.031 ± 1.684
4.222LeuGlu: 4.222 ± 1.351
4.825LeuPhe: 4.825 ± 1.58
6.634LeuGly: 6.634 ± 2.262
1.809LeuHis: 1.809 ± 0.689
4.825LeuIle: 4.825 ± 1.197
10.253LeuLys: 10.253 ± 2.099
4.222LeuLeu: 4.222 ± 1.842
2.413LeuMet: 2.413 ± 1.277
5.428LeuAsn: 5.428 ± 1.575
4.825LeuPro: 4.825 ± 2.093
1.809LeuGln: 1.809 ± 1.22
6.031LeuArg: 6.031 ± 1.563
9.047LeuSer: 9.047 ± 3.257
4.222LeuThr: 4.222 ± 1.327
3.016LeuVal: 3.016 ± 0.641
0.603LeuTrp: 0.603 ± 0.413
3.016LeuTyr: 3.016 ± 1.49
0.0LeuXaa: 0.0 ± 0.0
Met
3.619MetAla: 3.619 ± 0.965
0.603MetCys: 0.603 ± 0.533
3.016MetAsp: 3.016 ± 1.016
0.0MetGlu: 0.0 ± 0.0
1.206MetPhe: 1.206 ± 0.706
0.603MetGly: 0.603 ± 0.527
0.0MetHis: 0.0 ± 0.0
0.603MetIle: 0.603 ± 0.413
3.016MetLys: 3.016 ± 2.187
3.016MetLeu: 3.016 ± 1.538
0.0MetMet: 0.0 ± 0.0
1.206MetAsn: 1.206 ± 0.496
1.206MetPro: 1.206 ± 1.085
0.603MetGln: 0.603 ± 0.533
1.809MetArg: 1.809 ± 1.391
3.016MetSer: 3.016 ± 1.225
1.206MetThr: 1.206 ± 0.827
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.206MetTyr: 1.206 ± 0.986
0.0MetXaa: 0.0 ± 0.0
Asn
4.222AsnAla: 4.222 ± 1.287
1.206AsnCys: 1.206 ± 0.495
3.016AsnAsp: 3.016 ± 1.009
0.603AsnGlu: 0.603 ± 0.527
2.413AsnPhe: 2.413 ± 0.821
4.825AsnGly: 4.825 ± 1.19
0.603AsnHis: 0.603 ± 0.695
2.413AsnIle: 2.413 ± 0.893
2.413AsnLys: 2.413 ± 0.893
6.031AsnLeu: 6.031 ± 2.041
0.0AsnMet: 0.0 ± 0.0
3.016AsnAsn: 3.016 ± 1.407
2.413AsnPro: 2.413 ± 1.256
1.206AsnGln: 1.206 ± 0.68
1.809AsnArg: 1.809 ± 0.937
3.619AsnSer: 3.619 ± 1.346
3.619AsnThr: 3.619 ± 1.872
3.619AsnVal: 3.619 ± 0.932
0.603AsnTrp: 0.603 ± 0.533
3.016AsnTyr: 3.016 ± 1.562
0.0AsnXaa: 0.0 ± 0.0
Pro
3.016ProAla: 3.016 ± 1.373
0.0ProCys: 0.0 ± 0.0
3.016ProAsp: 3.016 ± 1.135
3.619ProGlu: 3.619 ± 1.872
3.619ProPhe: 3.619 ± 1.479
0.603ProGly: 0.603 ± 0.413
1.206ProHis: 1.206 ± 0.986
0.603ProIle: 0.603 ± 0.413
1.206ProLys: 1.206 ± 1.237
3.619ProLeu: 3.619 ± 0.965
1.809ProMet: 1.809 ± 1.468
2.413ProAsn: 2.413 ± 0.911
1.809ProPro: 1.809 ± 0.74
0.0ProGln: 0.0 ± 0.0
1.206ProArg: 1.206 ± 0.827
4.222ProSer: 4.222 ± 2.343
2.413ProThr: 2.413 ± 0.849
3.619ProVal: 3.619 ± 1.96
1.206ProTrp: 1.206 ± 0.752
3.619ProTyr: 3.619 ± 0.876
0.0ProXaa: 0.0 ± 0.0
Gln
2.413GlnAla: 2.413 ± 2.109
0.0GlnCys: 0.0 ± 0.0
3.016GlnAsp: 3.016 ± 1.062
1.809GlnGlu: 1.809 ± 0.746
2.413GlnPhe: 2.413 ± 0.585
1.809GlnGly: 1.809 ± 0.986
0.603GlnHis: 0.603 ± 1.271
3.619GlnIle: 3.619 ± 1.873
4.825GlnLys: 4.825 ± 3.244
3.016GlnLeu: 3.016 ± 1.588
1.206GlnMet: 1.206 ± 0.697
1.206GlnAsn: 1.206 ± 1.334
1.206GlnPro: 1.206 ± 0.827
1.809GlnGln: 1.809 ± 1.115
1.809GlnArg: 1.809 ± 0.493
4.825GlnSer: 4.825 ± 1.225
3.016GlnThr: 3.016 ± 2.067
0.603GlnVal: 0.603 ± 0.413
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.222ArgAla: 4.222 ± 1.352
1.206ArgCys: 1.206 ± 0.848
3.016ArgAsp: 3.016 ± 1.294
6.031ArgGlu: 6.031 ± 2.309
1.809ArgPhe: 1.809 ± 0.898
2.413ArgGly: 2.413 ± 1.449
1.206ArgHis: 1.206 ± 0.495
4.222ArgIle: 4.222 ± 1.437
2.413ArgLys: 2.413 ± 1.436
4.825ArgLeu: 4.825 ± 1.124
1.809ArgMet: 1.809 ± 1.128
3.016ArgAsn: 3.016 ± 1.13
1.809ArgPro: 1.809 ± 1.6
0.603ArgGln: 0.603 ± 0.413
4.222ArgArg: 4.222 ± 1.925
3.016ArgSer: 3.016 ± 1.887
3.619ArgThr: 3.619 ± 0.804
3.619ArgVal: 3.619 ± 1.705
0.603ArgTrp: 0.603 ± 0.413
3.619ArgTyr: 3.619 ± 1.273
0.0ArgXaa: 0.0 ± 0.0
Ser
9.65SerAla: 9.65 ± 1.92
0.603SerCys: 0.603 ± 1.271
11.46SerAsp: 11.46 ± 3.19
1.206SerGlu: 1.206 ± 0.68
3.016SerPhe: 3.016 ± 0.953
9.65SerGly: 9.65 ± 2.901
1.809SerHis: 1.809 ± 1.284
9.047SerIle: 9.047 ± 4.547
4.825SerLys: 4.825 ± 1.318
12.063SerLeu: 12.063 ± 2.088
1.206SerMet: 1.206 ± 1.334
3.016SerAsn: 3.016 ± 1.403
5.428SerPro: 5.428 ± 1.59
4.825SerGln: 4.825 ± 2.334
2.413SerArg: 2.413 ± 0.585
8.444SerSer: 8.444 ± 1.853
3.619SerThr: 3.619 ± 1.399
6.031SerVal: 6.031 ± 1.928
0.603SerTrp: 0.603 ± 0.533
6.031SerTyr: 6.031 ± 1.92
0.0SerXaa: 0.0 ± 0.0
Thr
3.016ThrAla: 3.016 ± 1.081
1.206ThrCys: 1.206 ± 0.495
1.206ThrAsp: 1.206 ± 0.68
3.016ThrGlu: 3.016 ± 1.081
1.809ThrPhe: 1.809 ± 0.74
4.825ThrGly: 4.825 ± 1.132
1.206ThrHis: 1.206 ± 0.68
1.809ThrIle: 1.809 ± 2.552
0.603ThrLys: 0.603 ± 0.533
6.634ThrLeu: 6.634 ± 1.587
0.603ThrMet: 0.603 ± 0.413
3.619ThrAsn: 3.619 ± 1.087
1.809ThrPro: 1.809 ± 0.898
3.619ThrGln: 3.619 ± 1.506
3.016ThrArg: 3.016 ± 0.641
10.856ThrSer: 10.856 ± 2.431
3.016ThrThr: 3.016 ± 1.361
1.809ThrVal: 1.809 ± 0.74
0.0ThrTrp: 0.0 ± 0.0
1.809ThrTyr: 1.809 ± 0.689
0.0ThrXaa: 0.0 ± 0.0
Val
3.016ValAla: 3.016 ± 2.615
1.206ValCys: 1.206 ± 0.495
3.016ValAsp: 3.016 ± 1.244
1.809ValGlu: 1.809 ± 1.49
1.206ValPhe: 1.206 ± 1.237
1.206ValGly: 1.206 ± 0.697
0.0ValHis: 0.0 ± 0.0
2.413ValIle: 2.413 ± 0.821
3.016ValLys: 3.016 ± 1.189
3.619ValLeu: 3.619 ± 1.521
1.206ValMet: 1.206 ± 0.496
1.206ValAsn: 1.206 ± 0.496
3.619ValPro: 3.619 ± 1.354
2.413ValGln: 2.413 ± 0.751
3.016ValArg: 3.016 ± 1.562
9.047ValSer: 9.047 ± 3.188
2.413ValThr: 2.413 ± 0.682
1.809ValVal: 1.809 ± 1.751
0.603ValTrp: 0.603 ± 0.413
4.222ValTyr: 4.222 ± 1.62
0.0ValXaa: 0.0 ± 0.0
Trp
0.603TrpAla: 0.603 ± 0.413
0.0TrpCys: 0.0 ± 0.0
1.206TrpAsp: 1.206 ± 0.697
0.603TrpGlu: 0.603 ± 0.533
1.206TrpPhe: 1.206 ± 0.827
1.206TrpGly: 1.206 ± 0.827
0.603TrpHis: 0.603 ± 0.533
0.603TrpIle: 0.603 ± 1.271
0.603TrpLys: 0.603 ± 0.533
1.206TrpLeu: 1.206 ± 0.752
0.0TrpMet: 0.0 ± 0.0
1.206TrpAsn: 1.206 ± 0.495
0.0TrpPro: 0.0 ± 0.0
1.206TrpGln: 1.206 ± 0.496
0.603TrpArg: 0.603 ± 0.413
0.603TrpSer: 0.603 ± 0.533
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.603TrpTyr: 0.603 ± 0.413
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.206TyrAla: 1.206 ± 0.706
0.0TyrCys: 0.0 ± 0.0
3.619TyrAsp: 3.619 ± 1.127
2.413TyrGlu: 2.413 ± 1.01
2.413TyrPhe: 2.413 ± 1.264
6.031TyrGly: 6.031 ± 2.78
1.809TyrHis: 1.809 ± 1.215
3.619TyrIle: 3.619 ± 0.847
3.016TyrLys: 3.016 ± 0.953
5.428TyrLeu: 5.428 ± 2.156
1.809TyrMet: 1.809 ± 0.942
3.016TyrAsn: 3.016 ± 1.135
3.016TyrPro: 3.016 ± 1.234
3.016TyrGln: 3.016 ± 1.197
1.206TyrArg: 1.206 ± 0.848
3.619TyrSer: 3.619 ± 1.528
1.206TyrThr: 1.206 ± 1.46
1.206TyrVal: 1.206 ± 0.495
1.206TyrTrp: 1.206 ± 1.067
1.206TyrTyr: 1.206 ± 0.906
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1659 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski