Amino acid dipepetide frequency for Kwoniella dejecticola CBS 10117

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.5AlaAla: 7.5 ± 0.068	0.813AlaCys: 0.813 ± 0.014	3.76AlaAsp: 3.76 ± 0.027	5.056AlaGlu: 5.056 ± 0.044	2.743AlaPhe: 2.743 ± 0.027	5.723AlaGly: 5.723 ± 0.038	1.699AlaHis: 1.699 ± 0.023	4.113AlaIle: 4.113 ± 0.036	4.242AlaLys: 4.242 ± 0.038	7.148AlaLeu: 7.148 ± 0.049	1.707AlaMet: 1.707 ± 0.021	2.963AlaAsn: 2.963 ± 0.032	4.628AlaPro: 4.628 ± 0.058	3.556AlaGln: 3.556 ± 0.036	4.331AlaArg: 4.331 ± 0.034	7.949AlaSer: 7.949 ± 0.062	4.679AlaThr: 4.679 ± 0.044	4.465AlaVal: 4.465 ± 0.034	1.0AlaTrp: 1.0 ± 0.018	2.012AlaTyr: 2.012 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.689CysAla: 0.689 ± 0.014	0.169CysCys: 0.169 ± 0.007	0.508CysAsp: 0.508 ± 0.013	0.51CysGlu: 0.51 ± 0.012	0.414CysPhe: 0.414 ± 0.011	0.75CysGly: 0.75 ± 0.019	0.257CysHis: 0.257 ± 0.008	0.567CysIle: 0.567 ± 0.012	0.434CysLys: 0.434 ± 0.011	1.045CysLeu: 1.045 ± 0.017	0.21CysMet: 0.21 ± 0.006	0.319CysAsn: 0.319 ± 0.009	0.547CysPro: 0.547 ± 0.013	0.379CysGln: 0.379 ± 0.01	0.517CysArg: 0.517 ± 0.011	0.719CysSer: 0.719 ± 0.015	0.57CysThr: 0.57 ± 0.013	0.614CysVal: 0.614 ± 0.014	0.168CysTrp: 0.168 ± 0.007	0.296CysTyr: 0.296 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.016AspAla: 4.016 ± 0.03	0.501AspCys: 0.501 ± 0.011	4.364AspAsp: 4.364 ± 0.042	5.081AspGlu: 5.081 ± 0.051	1.862AspPhe: 1.862 ± 0.024	4.094AspGly: 4.094 ± 0.028	1.353AspHis: 1.353 ± 0.021	2.98AspIle: 2.98 ± 0.028	2.676AspLys: 2.676 ± 0.028	5.212AspLeu: 5.212 ± 0.044	1.177AspMet: 1.177 ± 0.016	1.898AspAsn: 1.898 ± 0.021	3.353AspPro: 3.353 ± 0.032	2.238AspGln: 2.238 ± 0.022	3.072AspArg: 3.072 ± 0.035	3.98AspSer: 3.98 ± 0.029	2.879AspThr: 2.879 ± 0.029	3.451AspVal: 3.451 ± 0.033	0.881AspTrp: 0.881 ± 0.015	1.446AspTyr: 1.446 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	4.843GluAla: 4.843 ± 0.042	0.54GluCys: 0.54 ± 0.012	4.752GluAsp: 4.752 ± 0.046	6.444GluGlu: 6.444 ± 0.067	1.626GluPhe: 1.626 ± 0.019	4.661GluGly: 4.661 ± 0.039	1.287GluHis: 1.287 ± 0.02	3.301GluIle: 3.301 ± 0.028	4.064GluLys: 4.064 ± 0.046	4.907GluLeu: 4.907 ± 0.046	1.514GluMet: 1.514 ± 0.021	2.421GluAsn: 2.421 ± 0.028	2.423GluPro: 2.423 ± 0.027	2.389GluGln: 2.389 ± 0.025	4.006GluArg: 4.006 ± 0.039	4.327GluSer: 4.327 ± 0.03	3.13GluThr: 3.13 ± 0.029	3.715GluVal: 3.715 ± 0.038	0.939GluTrp: 0.939 ± 0.015	1.649GluTyr: 1.649 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.739PheAla: 2.739 ± 0.029	0.429PheCys: 0.429 ± 0.011	2.132PheAsp: 2.132 ± 0.021	1.923PheGlu: 1.923 ± 0.023	1.356PhePhe: 1.356 ± 0.021	2.744PheGly: 2.744 ± 0.038	0.763PheHis: 0.763 ± 0.015	1.647PheIle: 1.647 ± 0.024	1.458PheLys: 1.458 ± 0.019	2.963PheLeu: 2.963 ± 0.035	0.673PheMet: 0.673 ± 0.013	1.306PheAsn: 1.306 ± 0.017	1.817PhePro: 1.817 ± 0.023	1.129PheGln: 1.129 ± 0.017	1.635PheArg: 1.635 ± 0.02	2.814PheSer: 2.814 ± 0.027	1.977PheThr: 1.977 ± 0.02	2.059PheVal: 2.059 ± 0.027	0.525PheTrp: 0.525 ± 0.014	0.922PheTyr: 0.922 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.769GlyAla: 4.769 ± 0.039	0.764GlyCys: 0.764 ± 0.017	3.679GlyAsp: 3.679 ± 0.029	4.256GlyGlu: 4.256 ± 0.035	2.497GlyPhe: 2.497 ± 0.029	6.756GlyGly: 6.756 ± 0.08	1.678GlyHis: 1.678 ± 0.024	3.637GlyIle: 3.637 ± 0.037	4.179GlyLys: 4.179 ± 0.033	6.269GlyLeu: 6.269 ± 0.043	1.793GlyMet: 1.793 ± 0.026	2.85GlyAsn: 2.85 ± 0.028	3.355GlyPro: 3.355 ± 0.035	2.946GlyGln: 2.946 ± 0.032	4.027GlyArg: 4.027 ± 0.034	6.52GlySer: 6.52 ± 0.054	3.964GlyThr: 3.964 ± 0.036	4.325GlyVal: 4.325 ± 0.04	1.302GlyTrp: 1.302 ± 0.017	2.176GlyTyr: 2.176 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	1.685HisAla: 1.685 ± 0.022	0.234HisCys: 0.234 ± 0.008	1.243HisAsp: 1.243 ± 0.016	1.25HisGlu: 1.25 ± 0.018	0.815HisPhe: 0.815 ± 0.013	1.548HisGly: 1.548 ± 0.023	0.927HisHis: 0.927 ± 0.021	1.163HisIle: 1.163 ± 0.015	0.922HisLys: 0.922 ± 0.016	2.402HisLeu: 2.402 ± 0.026	0.401HisMet: 0.401 ± 0.01	0.857HisAsn: 0.857 ± 0.014	1.93HisPro: 1.93 ± 0.023	1.113HisGln: 1.113 ± 0.019	1.414HisArg: 1.414 ± 0.022	2.119HisSer: 2.119 ± 0.023	1.425HisThr: 1.425 ± 0.021	1.242HisVal: 1.242 ± 0.016	0.293HisTrp: 0.293 ± 0.008	0.604HisTyr: 0.604 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.117IleAla: 4.117 ± 0.036	0.635IleCys: 0.635 ± 0.014	3.084IleAsp: 3.084 ± 0.029	2.977IleGlu: 2.977 ± 0.027	1.803IlePhe: 1.803 ± 0.021	3.439IleGly: 3.439 ± 0.041	1.242IleHis: 1.242 ± 0.016	2.657IleIle: 2.657 ± 0.032	2.539IleLys: 2.539 ± 0.028	4.52IleLeu: 4.52 ± 0.045	0.968IleMet: 0.968 ± 0.015	1.95IleAsn: 1.95 ± 0.025	3.784IlePro: 3.784 ± 0.033	1.887IleGln: 1.887 ± 0.02	2.854IleArg: 2.854 ± 0.027	4.514IleSer: 4.514 ± 0.042	2.938IleThr: 2.938 ± 0.025	2.997IleVal: 2.997 ± 0.027	0.727IleTrp: 0.727 ± 0.014	1.333IleTyr: 1.333 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.555LysAla: 4.555 ± 0.041	0.417LysCys: 0.417 ± 0.011	3.062LysAsp: 3.062 ± 0.03	3.916LysGlu: 3.916 ± 0.037	1.328LysPhe: 1.328 ± 0.018	3.769LysGly: 3.769 ± 0.035	1.082LysHis: 1.082 ± 0.017	2.531LysIle: 2.531 ± 0.03	3.873LysLys: 3.873 ± 0.05	3.982LysLeu: 3.982 ± 0.033	1.068LysMet: 1.068 ± 0.016	1.786LysAsn: 1.786 ± 0.022	2.792LysPro: 2.792 ± 0.03	1.827LysGln: 1.827 ± 0.022	3.645LysArg: 3.645 ± 0.03	4.127LysSer: 4.127 ± 0.035	2.82LysThr: 2.82 ± 0.025	3.031LysVal: 3.031 ± 0.03	0.727LysTrp: 0.727 ± 0.011	1.299LysTyr: 1.299 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.172LeuAla: 7.172 ± 0.05	0.93LeuCys: 0.93 ± 0.016	5.005LeuAsp: 5.005 ± 0.04	5.143LeuGlu: 5.143 ± 0.046	3.017LeuPhe: 3.017 ± 0.032	5.917LeuGly: 5.917 ± 0.041	2.052LeuHis: 2.052 ± 0.02	4.282LeuIle: 4.282 ± 0.039	4.334LeuLys: 4.334 ± 0.04	7.993LeuLeu: 7.993 ± 0.067	1.609LeuMet: 1.609 ± 0.019	3.371LeuAsn: 3.371 ± 0.027	6.359LeuPro: 6.359 ± 0.047	3.274LeuGln: 3.274 ± 0.033	5.031LeuArg: 5.031 ± 0.04	8.083LeuSer: 8.083 ± 0.05	4.998LeuThr: 4.998 ± 0.037	4.864LeuVal: 4.864 ± 0.04	1.016LeuTrp: 1.016 ± 0.017	2.098LeuTyr: 2.098 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	1.7MetAla: 1.7 ± 0.021	0.188MetCys: 0.188 ± 0.006	1.213MetAsp: 1.213 ± 0.019	1.143MetGlu: 1.143 ± 0.016	0.662MetPhe: 0.662 ± 0.014	1.556MetGly: 1.556 ± 0.026	0.358MetHis: 0.358 ± 0.01	1.083MetIle: 1.083 ± 0.017	0.986MetLys: 0.986 ± 0.018	1.592MetLeu: 1.592 ± 0.02	0.575MetMet: 0.575 ± 0.013	0.8MetAsn: 0.8 ± 0.012	1.226MetPro: 1.226 ± 0.019	0.716MetGln: 0.716 ± 0.014	1.171MetArg: 1.171 ± 0.016	2.168MetSer: 2.168 ± 0.024	1.361MetThr: 1.361 ± 0.015	1.134MetVal: 1.134 ± 0.015	0.226MetTrp: 0.226 ± 0.008	0.481MetTyr: 0.481 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.285AsnAla: 3.285 ± 0.028	0.334AsnCys: 0.334 ± 0.011	2.167AsnAsp: 2.167 ± 0.023	2.22AsnGlu: 2.22 ± 0.024	1.182AsnPhe: 1.182 ± 0.016	3.56AsnGly: 3.56 ± 0.036	0.938AsnHis: 0.938 ± 0.015	1.877AsnIle: 1.877 ± 0.025	1.759AsnLys: 1.759 ± 0.023	3.382AsnLeu: 3.382 ± 0.033	0.736AsnMet: 0.736 ± 0.014	1.697AsnAsn: 1.697 ± 0.025	2.704AsnPro: 2.704 ± 0.029	1.608AsnGln: 1.608 ± 0.017	1.932AsnArg: 1.932 ± 0.02	3.166AsnSer: 3.166 ± 0.033	2.474AsnThr: 2.474 ± 0.029	2.26AsnVal: 2.26 ± 0.023	0.478AsnTrp: 0.478 ± 0.013	0.936AsnTyr: 0.936 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.169ProAla: 5.169 ± 0.054	0.393ProCys: 0.393 ± 0.011	3.03ProAsp: 3.03 ± 0.031	3.497ProGlu: 3.497 ± 0.032	2.116ProPhe: 2.116 ± 0.024	3.592ProGly: 3.592 ± 0.036	1.564ProHis: 1.564 ± 0.022	3.315ProIle: 3.315 ± 0.032	2.864ProLys: 2.864 ± 0.032	5.323ProLeu: 5.323 ± 0.036	1.024ProMet: 1.024 ± 0.019	2.58ProAsn: 2.58 ± 0.029	6.423ProPro: 6.423 ± 0.089	2.597ProGln: 2.597 ± 0.038	3.201ProArg: 3.201 ± 0.037	8.263ProSer: 8.263 ± 0.081	4.867ProThr: 4.867 ± 0.046	3.295ProVal: 3.295 ± 0.035	0.6ProTrp: 0.6 ± 0.013	1.574ProTyr: 1.574 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.754GlnAla: 3.754 ± 0.033	0.355GlnCys: 0.355 ± 0.01	2.059GlnAsp: 2.059 ± 0.023	2.271GlnGlu: 2.271 ± 0.028	1.084GlnPhe: 1.084 ± 0.018	2.672GlnGly: 2.672 ± 0.027	1.089GlnHis: 1.089 ± 0.02	1.984GlnIle: 1.984 ± 0.023	1.765GlnLys: 1.765 ± 0.02	3.225GlnLeu: 3.225 ± 0.028	0.869GlnMet: 0.869 ± 0.015	1.677GlnAsn: 1.677 ± 0.022	2.819GlnPro: 2.819 ± 0.036	2.584GlnGln: 2.584 ± 0.083	2.281GlnArg: 2.281 ± 0.021	3.647GlnSer: 3.647 ± 0.036	2.394GlnThr: 2.394 ± 0.028	2.157GlnVal: 2.157 ± 0.025	0.507GlnTrp: 0.507 ± 0.01	1.098GlnTyr: 1.098 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.136ArgAla: 4.136 ± 0.037	0.541ArgCys: 0.541 ± 0.012	3.137ArgAsp: 3.137 ± 0.033	3.658ArgGlu: 3.658 ± 0.033	1.822ArgPhe: 1.822 ± 0.022	3.613ArgGly: 3.613 ± 0.035	1.359ArgHis: 1.359 ± 0.02	2.827ArgIle: 2.827 ± 0.028	3.48ArgLys: 3.48 ± 0.031	4.944ArgLeu: 4.944 ± 0.035	1.239ArgMet: 1.239 ± 0.018	2.14ArgAsn: 2.14 ± 0.024	3.556ArgPro: 3.556 ± 0.039	2.409ArgGln: 2.409 ± 0.026	4.748ArgArg: 4.748 ± 0.05	5.357ArgSer: 5.357 ± 0.051	3.059ArgThr: 3.059 ± 0.026	2.878ArgVal: 2.878 ± 0.029	0.831ArgTrp: 0.831 ± 0.016	1.575ArgTyr: 1.575 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.899SerAla: 7.899 ± 0.059	0.7SerCys: 0.7 ± 0.016	4.537SerAsp: 4.537 ± 0.038	4.45SerGlu: 4.45 ± 0.037	2.988SerPhe: 2.988 ± 0.029	6.376SerGly: 6.376 ± 0.048	2.239SerHis: 2.239 ± 0.027	4.612SerIle: 4.612 ± 0.039	4.326SerLys: 4.326 ± 0.038	7.666SerLeu: 7.666 ± 0.047	1.69SerMet: 1.69 ± 0.022	3.804SerAsn: 3.804 ± 0.033	6.861SerPro: 6.861 ± 0.076	3.62SerGln: 3.62 ± 0.032	5.296SerArg: 5.296 ± 0.055	12.955SerSer: 12.955 ± 0.132	7.435SerThr: 7.435 ± 0.071	4.512SerVal: 4.512 ± 0.035	1.027SerTrp: 1.027 ± 0.017	2.123SerTyr: 2.123 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	4.961ThrAla: 4.961 ± 0.049	0.608ThrCys: 0.608 ± 0.015	2.786ThrAsp: 2.786 ± 0.029	2.888ThrGlu: 2.888 ± 0.028	2.187ThrPhe: 2.187 ± 0.026	4.099ThrGly: 4.099 ± 0.037	1.425ThrHis: 1.425 ± 0.019	3.257ThrIle: 3.257 ± 0.031	2.667ThrLys: 2.667 ± 0.025	5.319ThrLeu: 5.319 ± 0.036	1.043ThrMet: 1.043 ± 0.016	2.361ThrAsn: 2.361 ± 0.027	5.213ThrPro: 5.213 ± 0.052	2.27ThrGln: 2.27 ± 0.027	2.946ThrArg: 2.946 ± 0.028	7.0ThrSer: 7.0 ± 0.063	4.316ThrThr: 4.316 ± 0.045	3.177ThrVal: 3.177 ± 0.026	0.734ThrTrp: 0.734 ± 0.014	1.628ThrTyr: 1.628 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.163ValAla: 4.163 ± 0.039	0.625ValCys: 0.625 ± 0.013	3.543ValAsp: 3.543 ± 0.031	3.907ValGlu: 3.907 ± 0.044	2.0ValPhe: 2.0 ± 0.026	3.986ValGly: 3.986 ± 0.037	1.264ValHis: 1.264 ± 0.018	3.059ValIle: 3.059 ± 0.029	3.125ValLys: 3.125 ± 0.034	4.99ValLeu: 4.99 ± 0.035	1.169ValMet: 1.169 ± 0.016	2.259ValAsn: 2.259 ± 0.024	3.427ValPro: 3.427 ± 0.031	2.191ValGln: 2.191 ± 0.025	2.96ValArg: 2.96 ± 0.027	4.344ValSer: 4.344 ± 0.035	3.07ValThr: 3.07 ± 0.028	3.64ValVal: 3.64 ± 0.035	0.801ValTrp: 0.801 ± 0.014	1.493ValTyr: 1.493 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.958TrpAla: 0.958 ± 0.019	0.182TrpCys: 0.182 ± 0.007	0.862TrpAsp: 0.862 ± 0.016	0.873TrpGlu: 0.873 ± 0.016	0.472TrpPhe: 0.472 ± 0.012	0.915TrpGly: 0.915 ± 0.016	0.274TrpHis: 0.274 ± 0.007	0.731TrpIle: 0.731 ± 0.014	0.819TrpLys: 0.819 ± 0.014	1.188TrpLeu: 1.188 ± 0.016	0.34TrpMet: 0.34 ± 0.01	0.578TrpAsn: 0.578 ± 0.013	0.498TrpPro: 0.498 ± 0.012	0.488TrpGln: 0.488 ± 0.011	0.85TrpArg: 0.85 ± 0.014	1.07TrpSer: 1.07 ± 0.019	0.867TrpThr: 0.867 ± 0.017	0.788TrpVal: 0.788 ± 0.015	0.294TrpTrp: 0.294 ± 0.008	0.403TrpTyr: 0.403 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.978TyrAla: 1.978 ± 0.025	0.325TyrCys: 0.325 ± 0.01	1.59TyrAsp: 1.59 ± 0.022	1.475TyrGlu: 1.475 ± 0.022	1.036TyrPhe: 1.036 ± 0.018	1.97TyrGly: 1.97 ± 0.024	0.737TyrHis: 0.737 ± 0.014	1.342TyrIle: 1.342 ± 0.019	1.125TyrLys: 1.125 ± 0.017	2.479TyrLeu: 2.479 ± 0.025	0.536TyrMet: 0.536 ± 0.012	1.08TyrAsn: 1.08 ± 0.018	1.571TyrPro: 1.571 ± 0.024	1.073TyrGln: 1.073 ± 0.016	1.391TyrArg: 1.391 ± 0.017	1.992TyrSer: 1.992 ± 0.023	1.66TyrThr: 1.66 ± 0.019	1.411TyrVal: 1.411 ± 0.019	0.374TyrTrp: 0.374 ± 0.011	0.758TyrTyr: 0.758 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8600 proteins (4400537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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