Amino acid dipepetide frequency for Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.531AlaAla: 3.531 ± 0.044
0.648AlaCys: 0.648 ± 0.016
2.648AlaAsp: 2.648 ± 0.03
2.93AlaGlu: 2.93 ± 0.043
2.172AlaPhe: 2.172 ± 0.028
2.893AlaGly: 2.893 ± 0.044
0.958AlaHis: 0.958 ± 0.018
3.779AlaIle: 3.779 ± 0.039
3.83AlaLys: 3.83 ± 0.044
4.786AlaLeu: 4.786 ± 0.048
1.09AlaMet: 1.09 ± 0.022
3.319AlaAsn: 3.319 ± 0.039
2.171AlaPro: 2.171 ± 0.039
1.768AlaGln: 1.768 ± 0.029
2.077AlaArg: 2.077 ± 0.033
4.828AlaSer: 4.828 ± 0.052
3.137AlaThr: 3.137 ± 0.041
2.849AlaVal: 2.849 ± 0.034
0.464AlaTrp: 0.464 ± 0.013
1.719AlaTyr: 1.719 ± 0.028
0.0AlaXaa: 0.0 ± 0.0
Cys
0.538CysAla: 0.538 ± 0.015
0.252CysCys: 0.252 ± 0.01
0.67CysAsp: 0.67 ± 0.017
0.6CysGlu: 0.6 ± 0.015
0.659CysPhe: 0.659 ± 0.016
0.833CysGly: 0.833 ± 0.019
0.288CysHis: 0.288 ± 0.01
0.944CysIle: 0.944 ± 0.021
0.694CysLys: 0.694 ± 0.015
1.202CysLeu: 1.202 ± 0.023
0.267CysMet: 0.267 ± 0.011
0.624CysAsn: 0.624 ± 0.015
0.463CysPro: 0.463 ± 0.015
0.386CysGln: 0.386 ± 0.012
0.43CysArg: 0.43 ± 0.012
0.957CysSer: 0.957 ± 0.019
0.57CysThr: 0.57 ± 0.015
0.663CysVal: 0.663 ± 0.016
0.151CysTrp: 0.151 ± 0.007
0.463CysTyr: 0.463 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
2.891AspAla: 2.891 ± 0.035
0.601AspCys: 0.601 ± 0.015
5.074AspAsp: 5.074 ± 0.083
5.475AspGlu: 5.475 ± 0.06
2.785AspPhe: 2.785 ± 0.03
2.855AspGly: 2.855 ± 0.033
1.157AspHis: 1.157 ± 0.022
4.679AspIle: 4.679 ± 0.043
4.238AspLys: 4.238 ± 0.041
5.797AspLeu: 5.797 ± 0.049
1.239AspMet: 1.239 ± 0.019
3.846AspAsn: 3.846 ± 0.045
2.4AspPro: 2.4 ± 0.032
1.93AspGln: 1.93 ± 0.024
2.03AspArg: 2.03 ± 0.026
5.41AspSer: 5.41 ± 0.055
3.016AspThr: 3.016 ± 0.036
3.261AspVal: 3.261 ± 0.037
0.607AspTrp: 0.607 ± 0.014
2.429AspTyr: 2.429 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
3.355GluAla: 3.355 ± 0.044
0.648GluCys: 0.648 ± 0.018
4.559GluAsp: 4.559 ± 0.053
5.924GluGlu: 5.924 ± 0.081
2.901GluPhe: 2.901 ± 0.032
2.749GluGly: 2.749 ± 0.036
1.206GluHis: 1.206 ± 0.021
4.696GluIle: 4.696 ± 0.043
5.04GluLys: 5.04 ± 0.061
6.242GluLeu: 6.242 ± 0.055
1.327GluMet: 1.327 ± 0.02
4.489GluAsn: 4.489 ± 0.044
2.017GluPro: 2.017 ± 0.03
2.42GluGln: 2.42 ± 0.034
2.622GluArg: 2.622 ± 0.037
5.566GluSer: 5.566 ± 0.053
3.495GluThr: 3.495 ± 0.035
3.379GluVal: 3.379 ± 0.038
0.619GluTrp: 0.619 ± 0.015
2.434GluTyr: 2.434 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
2.372PheAla: 2.372 ± 0.036
0.553PheCys: 0.553 ± 0.014
2.936PheAsp: 2.936 ± 0.031
2.855PheGlu: 2.855 ± 0.034
2.04PhePhe: 2.04 ± 0.033
2.813PheGly: 2.813 ± 0.043
0.992PheHis: 0.992 ± 0.017
3.208PheIle: 3.208 ± 0.041
3.282PheLys: 3.282 ± 0.038
3.892PheLeu: 3.892 ± 0.045
0.966PheMet: 0.966 ± 0.018
3.066PheAsn: 3.066 ± 0.035
1.73PhePro: 1.73 ± 0.023
1.723PheGln: 1.723 ± 0.023
1.629PheArg: 1.629 ± 0.025
3.626PheSer: 3.626 ± 0.038
2.402PheThr: 2.402 ± 0.026
2.513PheVal: 2.513 ± 0.036
0.514PheTrp: 0.514 ± 0.016
1.59PheTyr: 1.59 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
2.9GlyAla: 2.9 ± 0.05
0.712GlyCys: 0.712 ± 0.017
2.971GlyAsp: 2.971 ± 0.038
2.923GlyGlu: 2.923 ± 0.035
2.606GlyPhe: 2.606 ± 0.034
3.538GlyGly: 3.538 ± 0.063
1.084GlyHis: 1.084 ± 0.021
3.819GlyIle: 3.819 ± 0.037
3.611GlyLys: 3.611 ± 0.038
4.854GlyLeu: 4.854 ± 0.043
1.055GlyMet: 1.055 ± 0.021
3.117GlyAsn: 3.117 ± 0.037
1.628GlyPro: 1.628 ± 0.028
1.626GlyGln: 1.626 ± 0.029
2.039GlyArg: 2.039 ± 0.031
4.917GlySer: 4.917 ± 0.079
2.815GlyThr: 2.815 ± 0.04
3.107GlyVal: 3.107 ± 0.043
0.611GlyTrp: 0.611 ± 0.015
2.061GlyTyr: 2.061 ± 0.031
0.0GlyXaa: 0.0 ± 0.0
His
0.971HisAla: 0.971 ± 0.02
0.269HisCys: 0.269 ± 0.01
1.208HisAsp: 1.208 ± 0.021
1.378HisGlu: 1.378 ± 0.022
0.924HisPhe: 0.924 ± 0.015
1.103HisGly: 1.103 ± 0.021
0.648HisHis: 0.648 ± 0.022
1.439HisIle: 1.439 ± 0.022
1.417HisLys: 1.417 ± 0.022
2.012HisLeu: 2.012 ± 0.027
0.4HisMet: 0.4 ± 0.012
1.326HisAsn: 1.326 ± 0.022
1.058HisPro: 1.058 ± 0.019
0.92HisGln: 0.92 ± 0.024
0.89HisArg: 0.89 ± 0.018
1.79HisSer: 1.79 ± 0.029
1.05HisThr: 1.05 ± 0.021
1.034HisVal: 1.034 ± 0.019
0.227HisTrp: 0.227 ± 0.011
0.808HisTyr: 0.808 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
3.65IleAla: 3.65 ± 0.037
0.891IleCys: 0.891 ± 0.02
4.792IleAsp: 4.792 ± 0.042
4.522IleGlu: 4.522 ± 0.044
3.064IlePhe: 3.064 ± 0.043
3.604IleGly: 3.604 ± 0.044
1.509IleHis: 1.509 ± 0.022
4.952IleIle: 4.952 ± 0.051
4.985IleLys: 4.985 ± 0.048
6.414IleLeu: 6.414 ± 0.059
1.421IleMet: 1.421 ± 0.024
4.752IleAsn: 4.752 ± 0.053
3.479IlePro: 3.479 ± 0.037
2.485IleGln: 2.485 ± 0.031
2.827IleArg: 2.827 ± 0.031
6.444IleSer: 6.444 ± 0.055
3.781IleThr: 3.781 ± 0.041
3.806IleVal: 3.806 ± 0.035
0.738IleTrp: 0.738 ± 0.018
2.344IleTyr: 2.344 ± 0.031
0.0IleXaa: 0.0 ± 0.0
Lys
3.645LysAla: 3.645 ± 0.047
0.773LysCys: 0.773 ± 0.015
4.389LysAsp: 4.389 ± 0.046
5.132LysGlu: 5.132 ± 0.056
3.332LysPhe: 3.332 ± 0.039
3.055LysGly: 3.055 ± 0.039
1.574LysHis: 1.574 ± 0.024
4.949LysIle: 4.949 ± 0.042
6.21LysLys: 6.21 ± 0.067
7.448LysLeu: 7.448 ± 0.067
1.366LysMet: 1.366 ± 0.021
4.536LysAsn: 4.536 ± 0.041
3.076LysPro: 3.076 ± 0.04
2.952LysGln: 2.952 ± 0.032
3.406LysArg: 3.406 ± 0.035
6.409LysSer: 6.409 ± 0.058
3.773LysThr: 3.773 ± 0.037
4.003LysVal: 4.003 ± 0.04
0.767LysTrp: 0.767 ± 0.015
2.959LysTyr: 2.959 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
5.03LeuAla: 5.03 ± 0.04
1.162LeuCys: 1.162 ± 0.022
5.197LeuAsp: 5.197 ± 0.046
5.542LeuGlu: 5.542 ± 0.053
4.0LeuPhe: 4.0 ± 0.049
4.62LeuGly: 4.62 ± 0.047
1.91LeuHis: 1.91 ± 0.025
6.595LeuIle: 6.595 ± 0.067
7.016LeuLys: 7.016 ± 0.061
8.485LeuLeu: 8.485 ± 0.081
1.934LeuMet: 1.934 ± 0.027
6.227LeuAsn: 6.227 ± 0.064
4.214LeuPro: 4.214 ± 0.036
3.714LeuGln: 3.714 ± 0.046
3.874LeuArg: 3.874 ± 0.04
8.685LeuSer: 8.685 ± 0.07
5.018LeuThr: 5.018 ± 0.043
5.178LeuVal: 5.178 ± 0.046
0.819LeuTrp: 0.819 ± 0.017
2.991LeuTyr: 2.991 ± 0.035
0.0LeuXaa: 0.0 ± 0.0
Met
1.255MetAla: 1.255 ± 0.022
0.257MetCys: 0.257 ± 0.009
1.219MetAsp: 1.219 ± 0.022
1.119MetGlu: 1.119 ± 0.02
0.845MetPhe: 0.845 ± 0.02
1.192MetGly: 1.192 ± 0.024
0.364MetHis: 0.364 ± 0.012
1.318MetIle: 1.318 ± 0.025
1.535MetLys: 1.535 ± 0.024
1.667MetLeu: 1.667 ± 0.025
0.484MetMet: 0.484 ± 0.015
1.448MetAsn: 1.448 ± 0.022
0.827MetPro: 0.827 ± 0.021
0.652MetGln: 0.652 ± 0.014
0.715MetArg: 0.715 ± 0.016
2.155MetSer: 2.155 ± 0.029
1.105MetThr: 1.105 ± 0.021
1.171MetVal: 1.171 ± 0.021
0.16MetTrp: 0.16 ± 0.007
0.653MetTyr: 0.653 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
3.082AsnAla: 3.082 ± 0.033
0.698AsnCys: 0.698 ± 0.016
4.646AsnAsp: 4.646 ± 0.053
4.894AsnGlu: 4.894 ± 0.051
2.842AsnPhe: 2.842 ± 0.035
3.484AsnGly: 3.484 ± 0.044
1.38AsnHis: 1.38 ± 0.026
4.489AsnIle: 4.489 ± 0.048
4.865AsnLys: 4.865 ± 0.047
5.771AsnLeu: 5.771 ± 0.056
1.297AsnMet: 1.297 ± 0.022
5.19AsnAsn: 5.19 ± 0.066
2.717AsnPro: 2.717 ± 0.035
2.544AsnGln: 2.544 ± 0.039
2.342AsnArg: 2.342 ± 0.035
6.299AsnSer: 6.299 ± 0.069
3.516AsnThr: 3.516 ± 0.038
3.277AsnVal: 3.277 ± 0.035
0.647AsnTrp: 0.647 ± 0.015
2.602AsnTyr: 2.602 ± 0.035
0.0AsnXaa: 0.0 ± 0.0
Pro
2.047ProAla: 2.047 ± 0.031
0.343ProCys: 0.343 ± 0.012
2.246ProAsp: 2.246 ± 0.029
2.939ProGlu: 2.939 ± 0.042
1.852ProPhe: 1.852 ± 0.023
1.957ProGly: 1.957 ± 0.032
0.879ProHis: 0.879 ± 0.016
3.012ProIle: 3.012 ± 0.038
3.013ProLys: 3.013 ± 0.035
3.548ProLeu: 3.548 ± 0.038
0.793ProMet: 0.793 ± 0.017
2.728ProAsn: 2.728 ± 0.036
2.407ProPro: 2.407 ± 0.061
1.836ProGln: 1.836 ± 0.033
1.598ProArg: 1.598 ± 0.024
4.28ProSer: 4.28 ± 0.048
2.689ProThr: 2.689 ± 0.041
2.479ProVal: 2.479 ± 0.031
0.378ProTrp: 0.378 ± 0.011
1.418ProTyr: 1.418 ± 0.024
0.0ProXaa: 0.0 ± 0.0
Gln
2.021GlnAla: 2.021 ± 0.031
0.377GlnCys: 0.377 ± 0.011
2.064GlnAsp: 2.064 ± 0.028
2.555GlnGlu: 2.555 ± 0.03
1.743GlnPhe: 1.743 ± 0.026
1.771GlnGly: 1.771 ± 0.03
0.889GlnHis: 0.889 ± 0.023
2.463GlnIle: 2.463 ± 0.032
2.544GlnLys: 2.544 ± 0.032
3.678GlnLeu: 3.678 ± 0.037
0.801GlnMet: 0.801 ± 0.018
2.361GlnAsn: 2.361 ± 0.032
1.707GlnPro: 1.707 ± 0.034
2.714GlnGln: 2.714 ± 0.086
1.581GlnArg: 1.581 ± 0.027
3.203GlnSer: 3.203 ± 0.038
1.916GlnThr: 1.916 ± 0.027
1.974GlnVal: 1.974 ± 0.028
0.343GlnTrp: 0.343 ± 0.011
1.418GlnTyr: 1.418 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
1.937ArgAla: 1.937 ± 0.027
0.462ArgCys: 0.462 ± 0.013
2.257ArgAsp: 2.257 ± 0.03
2.433ArgGlu: 2.433 ± 0.036
1.869ArgPhe: 1.869 ± 0.026
1.931ArgGly: 1.931 ± 0.03
0.883ArgHis: 0.883 ± 0.018
2.761ArgIle: 2.761 ± 0.03
3.31ArgLys: 3.31 ± 0.037
3.839ArgLeu: 3.839 ± 0.044
0.831ArgMet: 0.831 ± 0.017
2.57ArgAsn: 2.57 ± 0.033
1.557ArgPro: 1.557 ± 0.027
1.558ArgGln: 1.558 ± 0.023
2.375ArgArg: 2.375 ± 0.035
3.543ArgSer: 3.543 ± 0.041
2.021ArgThr: 2.021 ± 0.032
2.092ArgVal: 2.092 ± 0.029
0.413ArgTrp: 0.413 ± 0.013
1.471ArgTyr: 1.471 ± 0.023
0.0ArgXaa: 0.0 ± 0.0
Ser
4.325SerAla: 4.325 ± 0.042
0.931SerCys: 0.931 ± 0.021
5.371SerAsp: 5.371 ± 0.065
5.13SerGlu: 5.13 ± 0.047
4.014SerPhe: 4.014 ± 0.041
4.837SerGly: 4.837 ± 0.07
1.928SerHis: 1.928 ± 0.027
6.763SerIle: 6.763 ± 0.053
7.07SerLys: 7.07 ± 0.068
8.295SerLeu: 8.295 ± 0.066
1.838SerMet: 1.838 ± 0.029
6.708SerAsn: 6.708 ± 0.073
3.882SerPro: 3.882 ± 0.052
3.508SerGln: 3.508 ± 0.041
3.66SerArg: 3.66 ± 0.038
10.62SerSer: 10.62 ± 0.144
5.69SerThr: 5.69 ± 0.057
4.704SerVal: 4.704 ± 0.047
0.816SerTrp: 0.816 ± 0.018
2.932SerTyr: 2.932 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
2.787ThrAla: 2.787 ± 0.032
0.622ThrCys: 0.622 ± 0.017
3.016ThrAsp: 3.016 ± 0.033
3.103ThrGlu: 3.103 ± 0.041
2.325ThrPhe: 2.325 ± 0.03
3.18ThrGly: 3.18 ± 0.047
1.121ThrHis: 1.121 ± 0.021
3.907ThrIle: 3.907 ± 0.036
4.077ThrLys: 4.077 ± 0.036
4.716ThrLeu: 4.716 ± 0.046
0.999ThrMet: 0.999 ± 0.017
3.769ThrAsn: 3.769 ± 0.042
2.856ThrPro: 2.856 ± 0.037
1.833ThrGln: 1.833 ± 0.025
2.127ThrArg: 2.127 ± 0.026
5.402ThrSer: 5.402 ± 0.059
3.558ThrThr: 3.558 ± 0.074
2.952ThrVal: 2.952 ± 0.039
0.528ThrTrp: 0.528 ± 0.013
1.874ThrTyr: 1.874 ± 0.026
0.0ThrXaa: 0.0 ± 0.0
Val
3.084ValAla: 3.084 ± 0.036
0.704ValCys: 0.704 ± 0.018
3.479ValAsp: 3.479 ± 0.034
3.408ValGlu: 3.408 ± 0.036
2.432ValPhe: 2.432 ± 0.029
2.998ValGly: 2.998 ± 0.036
1.088ValHis: 1.088 ± 0.019
3.649ValIle: 3.649 ± 0.038
3.77ValLys: 3.77 ± 0.042
5.033ValLeu: 5.033 ± 0.046
1.099ValMet: 1.099 ± 0.021
3.42ValAsn: 3.42 ± 0.032
2.541ValPro: 2.541 ± 0.033
1.755ValGln: 1.755 ± 0.023
2.036ValArg: 2.036 ± 0.025
4.994ValSer: 4.994 ± 0.047
2.948ValThr: 2.948 ± 0.037
3.326ValVal: 3.326 ± 0.041
0.545ValTrp: 0.545 ± 0.017
1.919ValTyr: 1.919 ± 0.027
0.0ValXaa: 0.0 ± 0.0
Trp
0.489TrpAla: 0.489 ± 0.012
0.221TrpCys: 0.221 ± 0.007
0.622TrpAsp: 0.622 ± 0.016
0.544TrpGlu: 0.544 ± 0.014
0.543TrpPhe: 0.543 ± 0.015
0.546TrpGly: 0.546 ± 0.016
0.195TrpHis: 0.195 ± 0.008
0.662TrpIle: 0.662 ± 0.016
0.771TrpLys: 0.771 ± 0.018
0.976TrpLeu: 0.976 ± 0.02
0.202TrpMet: 0.202 ± 0.008
0.658TrpAsn: 0.658 ± 0.015
0.286TrpPro: 0.286 ± 0.011
0.304TrpGln: 0.304 ± 0.011
0.455TrpArg: 0.455 ± 0.014
0.841TrpSer: 0.841 ± 0.017
0.482TrpThr: 0.482 ± 0.014
0.551TrpVal: 0.551 ± 0.014
0.157TrpTrp: 0.157 ± 0.007
0.408TrpTyr: 0.408 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.688TyrAla: 1.688 ± 0.027
0.528TyrCys: 0.528 ± 0.015
2.355TyrAsp: 2.355 ± 0.026
2.282TyrGlu: 2.282 ± 0.026
1.755TyrPhe: 1.755 ± 0.028
2.039TyrGly: 2.039 ± 0.031
0.822TyrHis: 0.822 ± 0.017
2.376TyrIle: 2.376 ± 0.033
2.478TyrLys: 2.478 ± 0.034
3.556TyrLeu: 3.556 ± 0.037
0.731TyrMet: 0.731 ± 0.016
2.425TyrAsn: 2.425 ± 0.032
1.423TyrPro: 1.423 ± 0.026
1.495TyrGln: 1.495 ± 0.024
1.397TyrArg: 1.397 ± 0.023
3.053TyrSer: 3.053 ± 0.035
1.771TyrThr: 1.771 ± 0.028
1.906TyrVal: 1.906 ± 0.031
0.413TyrTrp: 0.413 ± 0.01
1.53TyrTyr: 1.53 ± 0.022
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6284 proteins (3008975 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski