Amino acid dipepetide frequency for Tortoise microvirus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.614AlaAla: 4.614 ± 2.054
1.73AlaCys: 1.73 ± 0.816
1.153AlaAsp: 1.153 ± 0.796
5.19AlaGlu: 5.19 ± 2.845
4.614AlaPhe: 4.614 ± 1.493
4.614AlaGly: 4.614 ± 1.529
1.153AlaHis: 1.153 ± 0.8
0.577AlaIle: 0.577 ± 0.521
2.884AlaLys: 2.884 ± 1.587
6.92AlaLeu: 6.92 ± 3.189
1.73AlaMet: 1.73 ± 0.731
4.037AlaAsn: 4.037 ± 2.217
4.614AlaPro: 4.614 ± 1.275
5.767AlaGln: 5.767 ± 3.818
5.19AlaArg: 5.19 ± 1.376
6.92AlaSer: 6.92 ± 2.76
3.46AlaThr: 3.46 ± 1.327
5.767AlaVal: 5.767 ± 1.427
0.577AlaTrp: 0.577 ± 0.596
1.73AlaTyr: 1.73 ± 0.778
0.0AlaXaa: 0.0 ± 0.0
Cys
0.577CysAla: 0.577 ± 0.596
0.577CysCys: 0.577 ± 0.789
1.153CysAsp: 1.153 ± 0.779
0.0CysGlu: 0.0 ± 0.0
1.73CysPhe: 1.73 ± 2.06
0.577CysGly: 0.577 ± 0.596
0.0CysHis: 0.0 ± 0.0
1.153CysIle: 1.153 ± 1.578
1.153CysLys: 1.153 ± 1.192
1.153CysLeu: 1.153 ± 0.838
0.577CysMet: 0.577 ± 0.596
0.577CysAsn: 0.577 ± 0.886
0.577CysPro: 0.577 ± 0.789
0.0CysGln: 0.0 ± 0.0
1.73CysArg: 1.73 ± 1.146
0.577CysSer: 0.577 ± 0.784
1.153CysThr: 1.153 ± 1.192
1.153CysVal: 1.153 ± 0.97
0.0CysTrp: 0.0 ± 0.0
1.153CysTyr: 1.153 ± 0.827
0.0CysXaa: 0.0 ± 0.0
Asp
5.767AspAla: 5.767 ± 2.61
0.577AspCys: 0.577 ± 0.596
5.19AspAsp: 5.19 ± 2.494
1.153AspGlu: 1.153 ± 0.906
6.92AspPhe: 6.92 ± 1.917
2.307AspGly: 2.307 ± 1.729
0.0AspHis: 0.0 ± 0.0
5.767AspIle: 5.767 ± 1.134
4.614AspLys: 4.614 ± 1.913
8.651AspLeu: 8.651 ± 3.098
3.46AspMet: 3.46 ± 1.128
2.884AspAsn: 2.884 ± 1.189
0.577AspPro: 0.577 ± 0.789
0.577AspGln: 0.577 ± 0.693
1.73AspArg: 1.73 ± 0.736
5.19AspSer: 5.19 ± 1.509
3.46AspThr: 3.46 ± 1.367
3.46AspVal: 3.46 ± 2.178
1.153AspTrp: 1.153 ± 0.628
4.037AspTyr: 4.037 ± 1.134
0.0AspXaa: 0.0 ± 0.0
Glu
1.153GluAla: 1.153 ± 0.796
0.0GluCys: 0.0 ± 0.0
1.153GluAsp: 1.153 ± 1.042
3.46GluGlu: 3.46 ± 1.576
2.307GluPhe: 2.307 ± 1.034
2.307GluGly: 2.307 ± 1.009
0.577GluHis: 0.577 ± 0.789
1.73GluIle: 1.73 ± 1.154
4.037GluLys: 4.037 ± 2.376
8.074GluLeu: 8.074 ± 3.602
0.577GluMet: 0.577 ± 0.521
1.73GluAsn: 1.73 ± 0.945
1.153GluPro: 1.153 ± 0.796
2.307GluGln: 2.307 ± 1.231
3.46GluArg: 3.46 ± 1.228
8.651GluSer: 8.651 ± 3.353
2.884GluThr: 2.884 ± 0.946
2.307GluVal: 2.307 ± 1.109
0.577GluTrp: 0.577 ± 0.428
1.73GluTyr: 1.73 ± 1.393
0.0GluXaa: 0.0 ± 0.0
Phe
3.46PheAla: 3.46 ± 1.07
1.153PheCys: 1.153 ± 1.192
2.884PheAsp: 2.884 ± 0.63
2.884PheGlu: 2.884 ± 1.189
3.46PhePhe: 3.46 ± 0.932
3.46PheGly: 3.46 ± 0.932
0.577PheHis: 0.577 ± 0.789
1.73PheIle: 1.73 ± 1.393
2.884PheLys: 2.884 ± 1.319
2.884PheLeu: 2.884 ± 0.63
1.73PheMet: 1.73 ± 1.131
7.497PheAsn: 7.497 ± 2.671
2.307PhePro: 2.307 ± 1.05
0.577PheGln: 0.577 ± 0.784
4.614PheArg: 4.614 ± 1.399
8.074PheSer: 8.074 ± 2.44
2.884PheThr: 2.884 ± 1.484
0.0PheVal: 0.0 ± 0.0
0.577PheTrp: 0.577 ± 0.428
0.577PheTyr: 0.577 ± 0.428
0.0PheXaa: 0.0 ± 0.0
Gly
5.767GlyAla: 5.767 ± 1.861
0.0GlyCys: 0.0 ± 0.0
5.767GlyAsp: 5.767 ± 2.046
0.577GlyGlu: 0.577 ± 0.596
2.307GlyPhe: 2.307 ± 0.607
4.614GlyGly: 4.614 ± 1.482
2.307GlyHis: 2.307 ± 1.145
6.92GlyIle: 6.92 ± 1.611
2.884GlyLys: 2.884 ± 1.48
8.651GlyLeu: 8.651 ± 2.578
2.307GlyMet: 2.307 ± 1.449
1.153GlyAsn: 1.153 ± 0.746
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
1.73GlyArg: 1.73 ± 1.265
9.227GlySer: 9.227 ± 3.204
2.884GlyThr: 2.884 ± 1.035
1.153GlyVal: 1.153 ± 0.627
0.0GlyTrp: 0.0 ± 0.0
4.614GlyTyr: 4.614 ± 1.971
0.0GlyXaa: 0.0 ± 0.0
His
1.73HisAla: 1.73 ± 0.778
0.0HisCys: 0.0 ± 0.0
1.153HisAsp: 1.153 ± 1.179
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.307HisGly: 2.307 ± 0.934
0.0HisHis: 0.0 ± 0.0
0.577HisIle: 0.577 ± 0.596
0.0HisLys: 0.0 ± 0.0
2.307HisLeu: 2.307 ± 1.236
0.577HisMet: 0.577 ± 0.784
0.577HisAsn: 0.577 ± 0.784
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.577HisArg: 0.577 ± 0.428
0.0HisSer: 0.0 ± 0.0
1.153HisThr: 1.153 ± 1.578
0.577HisVal: 0.577 ± 0.596
0.0HisTrp: 0.0 ± 0.0
1.153HisTyr: 1.153 ± 0.628
0.0HisXaa: 0.0 ± 0.0
Ile
4.037IleAla: 4.037 ± 1.774
0.577IleCys: 0.577 ± 0.789
2.307IleAsp: 2.307 ± 1.05
4.614IleGlu: 4.614 ± 3.185
1.153IlePhe: 1.153 ± 0.857
2.884IleGly: 2.884 ± 1.075
1.153IleHis: 1.153 ± 0.857
0.577IleIle: 0.577 ± 0.428
2.307IleLys: 2.307 ± 1.135
4.614IleLeu: 4.614 ± 1.62
1.153IleMet: 1.153 ± 0.857
4.037IleAsn: 4.037 ± 1.556
6.344IlePro: 6.344 ± 2.828
1.73IleGln: 1.73 ± 0.751
3.46IleArg: 3.46 ± 1.56
2.884IleSer: 2.884 ± 0.969
2.884IleThr: 2.884 ± 0.783
3.46IleVal: 3.46 ± 1.739
0.0IleTrp: 0.0 ± 0.0
2.884IleTyr: 2.884 ± 0.743
0.0IleXaa: 0.0 ± 0.0
Lys
6.344LysAla: 6.344 ± 3.29
0.0LysCys: 0.0 ± 0.0
2.307LysAsp: 2.307 ± 1.378
2.307LysGlu: 2.307 ± 1.198
1.153LysPhe: 1.153 ± 1.192
4.037LysGly: 4.037 ± 1.023
0.0LysHis: 0.0 ± 0.0
2.307LysIle: 2.307 ± 1.391
1.153LysLys: 1.153 ± 0.962
2.884LysLeu: 2.884 ± 0.705
3.46LysMet: 3.46 ± 0.71
3.46LysAsn: 3.46 ± 1.68
0.577LysPro: 0.577 ± 0.886
1.73LysGln: 1.73 ± 1.25
2.884LysArg: 2.884 ± 1.909
1.73LysSer: 1.73 ± 1.411
2.884LysThr: 2.884 ± 1.398
0.577LysVal: 0.577 ± 0.784
0.0LysTrp: 0.0 ± 0.0
2.307LysTyr: 2.307 ± 1.914
0.0LysXaa: 0.0 ± 0.0
Leu
5.19LeuAla: 5.19 ± 0.975
1.73LeuCys: 1.73 ± 1.2
7.497LeuAsp: 7.497 ± 2.103
6.344LeuGlu: 6.344 ± 2.968
4.614LeuPhe: 4.614 ± 1.455
5.19LeuGly: 5.19 ± 1.634
0.577LeuHis: 0.577 ± 0.784
5.19LeuIle: 5.19 ± 1.271
2.884LeuLys: 2.884 ± 1.406
3.46LeuLeu: 3.46 ± 1.104
1.153LeuMet: 1.153 ± 0.857
3.46LeuAsn: 3.46 ± 2.099
4.614LeuPro: 4.614 ± 2.886
5.19LeuGln: 5.19 ± 1.428
4.037LeuArg: 4.037 ± 2.046
9.804LeuSer: 9.804 ± 2.024
3.46LeuThr: 3.46 ± 1.511
3.46LeuVal: 3.46 ± 1.925
1.153LeuTrp: 1.153 ± 0.857
5.19LeuTyr: 5.19 ± 3.098
0.0LeuXaa: 0.0 ± 0.0
Met
3.46MetAla: 3.46 ± 1.82
0.577MetCys: 0.577 ± 0.784
3.46MetAsp: 3.46 ± 1.518
0.0MetGlu: 0.0 ± 0.0
1.73MetPhe: 1.73 ± 0.751
2.307MetGly: 2.307 ± 0.679
0.0MetHis: 0.0 ± 0.0
1.73MetIle: 1.73 ± 0.894
1.153MetLys: 1.153 ± 0.838
1.153MetLeu: 1.153 ± 0.779
1.153MetMet: 1.153 ± 0.484
2.884MetAsn: 2.884 ± 1.909
1.153MetPro: 1.153 ± 0.779
0.0MetGln: 0.0 ± 0.0
0.577MetArg: 0.577 ± 0.596
2.884MetSer: 2.884 ± 1.234
1.73MetThr: 1.73 ± 1.081
0.577MetVal: 0.577 ± 0.784
0.0MetTrp: 0.0 ± 0.0
3.46MetTyr: 3.46 ± 1.503
0.0MetXaa: 0.0 ± 0.0
Asn
5.767AsnAla: 5.767 ± 2.355
1.153AsnCys: 1.153 ± 0.746
4.037AsnAsp: 4.037 ± 1.776
2.884AsnGlu: 2.884 ± 1.359
4.037AsnPhe: 4.037 ± 1.017
1.73AsnGly: 1.73 ± 0.46
0.0AsnHis: 0.0 ± 0.0
1.153AsnIle: 1.153 ± 0.627
1.153AsnLys: 1.153 ± 0.857
3.46AsnLeu: 3.46 ± 0.739
1.73AsnMet: 1.73 ± 1.563
3.46AsnAsn: 3.46 ± 0.932
2.307AsnPro: 2.307 ± 1.008
1.73AsnGln: 1.73 ± 0.751
5.19AsnArg: 5.19 ± 2.649
4.037AsnSer: 4.037 ± 1.961
2.884AsnThr: 2.884 ± 0.957
5.19AsnVal: 5.19 ± 1.541
0.577AsnTrp: 0.577 ± 0.789
4.037AsnTyr: 4.037 ± 1.717
0.0AsnXaa: 0.0 ± 0.0
Pro
1.73ProAla: 1.73 ± 0.46
0.577ProCys: 0.577 ± 0.596
3.46ProAsp: 3.46 ± 2.053
2.307ProGlu: 2.307 ± 2.033
1.73ProPhe: 1.73 ± 0.894
1.153ProGly: 1.153 ± 0.627
0.577ProHis: 0.577 ± 0.596
6.344ProIle: 6.344 ± 2.605
1.153ProLys: 1.153 ± 0.962
2.884ProLeu: 2.884 ± 1.207
1.73ProMet: 1.73 ± 0.816
1.153ProAsn: 1.153 ± 0.627
0.577ProPro: 0.577 ± 0.596
1.73ProGln: 1.73 ± 1.285
1.73ProArg: 1.73 ± 0.926
7.497ProSer: 7.497 ± 2.022
1.73ProThr: 1.73 ± 1.285
4.037ProVal: 4.037 ± 1.409
0.0ProTrp: 0.0 ± 0.0
3.46ProTyr: 3.46 ± 2.188
0.0ProXaa: 0.0 ± 0.0
Gln
1.153GlnAla: 1.153 ± 0.779
1.153GlnCys: 1.153 ± 0.746
2.307GlnAsp: 2.307 ± 1.604
1.73GlnGlu: 1.73 ± 0.91
3.46GlnPhe: 3.46 ± 2.422
2.884GlnGly: 2.884 ± 0.733
0.0GlnHis: 0.0 ± 0.0
2.307GlnIle: 2.307 ± 0.757
0.577GlnLys: 0.577 ± 0.521
1.153GlnLeu: 1.153 ± 0.953
1.153GlnMet: 1.153 ± 1.042
1.153GlnAsn: 1.153 ± 0.627
1.73GlnPro: 1.73 ± 0.894
2.307GlnGln: 2.307 ± 2.084
4.614GlnArg: 4.614 ± 1.386
2.307GlnSer: 2.307 ± 1.123
1.153GlnThr: 1.153 ± 0.857
1.153GlnVal: 1.153 ± 0.8
0.577GlnTrp: 0.577 ± 0.521
1.73GlnTyr: 1.73 ± 0.91
0.0GlnXaa: 0.0 ± 0.0
Arg
2.884ArgAla: 2.884 ± 1.189
1.153ArgCys: 1.153 ± 0.97
4.614ArgAsp: 4.614 ± 1.103
4.614ArgGlu: 4.614 ± 1.47
1.153ArgPhe: 1.153 ± 0.796
2.307ArgGly: 2.307 ± 1.492
0.577ArgHis: 0.577 ± 0.596
2.884ArgIle: 2.884 ± 1.389
4.614ArgLys: 4.614 ± 2.891
5.767ArgLeu: 5.767 ± 1.535
1.73ArgMet: 1.73 ± 0.898
1.153ArgAsn: 1.153 ± 0.628
5.19ArgPro: 5.19 ± 2.681
2.307ArgGln: 2.307 ± 1.402
2.884ArgArg: 2.884 ± 1.779
7.497ArgSer: 7.497 ± 3.362
1.153ArgThr: 1.153 ± 0.862
2.307ArgVal: 2.307 ± 1.008
0.0ArgTrp: 0.0 ± 0.0
3.46ArgTyr: 3.46 ± 1.342
0.0ArgXaa: 0.0 ± 0.0
Ser
9.804SerAla: 9.804 ± 2.782
1.73SerCys: 1.73 ± 1.788
6.92SerAsp: 6.92 ± 2.269
4.037SerGlu: 4.037 ± 1.828
5.767SerPhe: 5.767 ± 1.191
11.534SerGly: 11.534 ± 2.805
1.73SerHis: 1.73 ± 0.46
4.614SerIle: 4.614 ± 1.216
1.73SerLys: 1.73 ± 0.915
6.344SerLeu: 6.344 ± 1.945
1.73SerMet: 1.73 ± 0.573
5.19SerAsn: 5.19 ± 2.192
4.614SerPro: 4.614 ± 1.327
4.037SerGln: 4.037 ± 1.05
3.46SerArg: 3.46 ± 1.367
12.687SerSer: 12.687 ± 4.348
6.92SerThr: 6.92 ± 2.395
6.92SerVal: 6.92 ± 2.131
0.577SerTrp: 0.577 ± 0.428
4.037SerTyr: 4.037 ± 1.687
0.0SerXaa: 0.0 ± 0.0
Thr
3.46ThrAla: 3.46 ± 0.682
0.0ThrCys: 0.0 ± 0.0
2.307ThrAsp: 2.307 ± 1.713
2.307ThrGlu: 2.307 ± 0.934
4.037ThrPhe: 4.037 ± 2.134
4.037ThrGly: 4.037 ± 1.318
1.153ThrHis: 1.153 ± 0.953
3.46ThrIle: 3.46 ± 0.959
2.884ThrLys: 2.884 ± 0.783
4.614ThrLeu: 4.614 ± 1.682
1.153ThrMet: 1.153 ± 0.707
2.884ThrAsn: 2.884 ± 0.974
1.153ThrPro: 1.153 ± 0.779
1.153ThrGln: 1.153 ± 0.484
3.46ThrArg: 3.46 ± 0.864
4.037ThrSer: 4.037 ± 1.83
1.153ThrThr: 1.153 ± 0.8
3.46ThrVal: 3.46 ± 1.222
0.577ThrTrp: 0.577 ± 0.428
1.153ThrTyr: 1.153 ± 1.192
0.0ThrXaa: 0.0 ± 0.0
Val
3.46ValAla: 3.46 ± 0.921
0.577ValCys: 0.577 ± 0.886
4.614ValAsp: 4.614 ± 1.359
2.884ValGlu: 2.884 ± 1.839
1.73ValPhe: 1.73 ± 0.926
1.73ValGly: 1.73 ± 0.751
1.153ValHis: 1.153 ± 0.746
1.153ValIle: 1.153 ± 0.8
2.884ValLys: 2.884 ± 1.721
5.19ValLeu: 5.19 ± 2.007
1.153ValMet: 1.153 ± 1.179
4.614ValAsn: 4.614 ± 1.482
5.19ValPro: 5.19 ± 1.872
0.577ValGln: 0.577 ± 0.886
2.884ValArg: 2.884 ± 0.976
6.344ValSer: 6.344 ± 1.731
0.577ValThr: 0.577 ± 0.596
1.153ValVal: 1.153 ± 0.838
0.0ValTrp: 0.0 ± 0.0
1.73ValTyr: 1.73 ± 1.081
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.577TrpCys: 0.577 ± 0.789
0.577TrpAsp: 0.577 ± 0.521
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.577TrpIle: 0.577 ± 0.428
0.0TrpLys: 0.0 ± 0.0
0.577TrpLeu: 0.577 ± 0.428
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.577TrpPro: 0.577 ± 0.428
1.153TrpGln: 1.153 ± 0.627
0.577TrpArg: 0.577 ± 0.596
0.577TrpSer: 0.577 ± 0.521
0.577TrpThr: 0.577 ± 0.428
0.577TrpVal: 0.577 ± 0.428
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.884TyrAla: 2.884 ± 1.328
1.73TyrCys: 1.73 ± 1.499
4.614TyrAsp: 4.614 ± 2.197
2.884TyrGlu: 2.884 ± 0.92
2.307TyrPhe: 2.307 ± 1.401
2.884TyrGly: 2.884 ± 1.389
1.153TyrHis: 1.153 ± 0.962
2.307TyrIle: 2.307 ± 1.253
1.153TyrLys: 1.153 ± 0.779
3.46TyrLeu: 3.46 ± 2.292
1.153TyrMet: 1.153 ± 0.857
4.614TyrAsn: 4.614 ± 1.554
2.307TyrPro: 2.307 ± 1.294
1.73TyrGln: 1.73 ± 0.894
3.46TyrArg: 3.46 ± 1.74
4.037TyrSer: 4.037 ± 1.755
3.46TyrThr: 3.46 ± 1.57
2.307TyrVal: 2.307 ± 1.594
0.0TyrTrp: 0.0 ± 0.0
2.307TyrTyr: 2.307 ± 1.123
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1735 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski