Amino acid dipepetide frequency for Tatumella ptyseos ATCC 33301

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.856AlaAla: 9.856 ± 0.149
1.107AlaCys: 1.107 ± 0.036
5.08AlaAsp: 5.08 ± 0.076
6.079AlaGlu: 6.079 ± 0.095
3.267AlaPhe: 3.267 ± 0.054
8.779AlaGly: 8.779 ± 0.138
1.643AlaHis: 1.643 ± 0.043
5.677AlaIle: 5.677 ± 0.089
3.16AlaLys: 3.16 ± 0.07
11.305AlaLeu: 11.305 ± 0.119
2.721AlaMet: 2.721 ± 0.051
2.544AlaAsn: 2.544 ± 0.056
3.583AlaPro: 3.583 ± 0.076
3.673AlaGln: 3.673 ± 0.065
5.721AlaArg: 5.721 ± 0.088
5.61AlaSer: 5.61 ± 0.074
4.798AlaThr: 4.798 ± 0.074
6.463AlaVal: 6.463 ± 0.097
1.297AlaTrp: 1.297 ± 0.039
1.953AlaTyr: 1.953 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
0.912CysAla: 0.912 ± 0.03
0.229CysCys: 0.229 ± 0.015
0.563CysAsp: 0.563 ± 0.022
0.59CysGlu: 0.59 ± 0.026
0.504CysPhe: 0.504 ± 0.023
1.158CysGly: 1.158 ± 0.031
0.365CysHis: 0.365 ± 0.022
0.578CysIle: 0.578 ± 0.025
0.277CysLys: 0.277 ± 0.018
1.208CysLeu: 1.208 ± 0.039
0.214CysMet: 0.214 ± 0.013
0.311CysAsn: 0.311 ± 0.015
0.495CysPro: 0.495 ± 0.024
0.563CysGln: 0.563 ± 0.026
0.75CysArg: 0.75 ± 0.03
0.698CysSer: 0.698 ± 0.03
0.489CysThr: 0.489 ± 0.02
0.651CysVal: 0.651 ± 0.027
0.217CysTrp: 0.217 ± 0.014
0.375CysTyr: 0.375 ± 0.021
0.0CysXaa: 0.0 ± 0.0
Asp
4.615AspAla: 4.615 ± 0.081
0.501AspCys: 0.501 ± 0.025
2.789AspAsp: 2.789 ± 0.059
3.187AspGlu: 3.187 ± 0.062
2.181AspPhe: 2.181 ± 0.052
3.535AspGly: 3.535 ± 0.075
1.132AspHis: 1.132 ± 0.034
3.672AspIle: 3.672 ± 0.067
2.421AspLys: 2.421 ± 0.054
4.613AspLeu: 4.613 ± 0.083
1.272AspMet: 1.272 ± 0.039
2.248AspAsn: 2.248 ± 0.053
2.532AspPro: 2.532 ± 0.048
1.96AspGln: 1.96 ± 0.047
2.604AspArg: 2.604 ± 0.059
3.06AspSer: 3.06 ± 0.054
2.759AspThr: 2.759 ± 0.057
3.467AspVal: 3.467 ± 0.071
0.766AspTrp: 0.766 ± 0.027
1.881AspTyr: 1.881 ± 0.041
0.0AspXaa: 0.0 ± 0.0
Glu
5.075GluAla: 5.075 ± 0.08
0.509GluCys: 0.509 ± 0.023
2.472GluAsp: 2.472 ± 0.064
3.207GluGlu: 3.207 ± 0.078
1.839GluPhe: 1.839 ± 0.04
3.52GluGly: 3.52 ± 0.064
1.411GluHis: 1.411 ± 0.036
3.37GluIle: 3.37 ± 0.066
3.167GluLys: 3.167 ± 0.063
5.695GluLeu: 5.695 ± 0.091
1.618GluMet: 1.618 ± 0.041
2.352GluAsn: 2.352 ± 0.045
1.959GluPro: 1.959 ± 0.049
3.472GluGln: 3.472 ± 0.085
3.304GluArg: 3.304 ± 0.073
3.077GluSer: 3.077 ± 0.059
3.004GluThr: 3.004 ± 0.063
3.544GluVal: 3.544 ± 0.069
0.736GluTrp: 0.736 ± 0.027
1.447GluTyr: 1.447 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
3.177PheAla: 3.177 ± 0.057
0.576PheCys: 0.576 ± 0.022
2.138PheAsp: 2.138 ± 0.052
1.626PheGlu: 1.626 ± 0.039
1.681PhePhe: 1.681 ± 0.051
3.06PheGly: 3.06 ± 0.064
0.811PheHis: 0.811 ± 0.033
2.721PheIle: 2.721 ± 0.056
1.108PheLys: 1.108 ± 0.035
3.418PheLeu: 3.418 ± 0.071
0.999PheMet: 0.999 ± 0.033
1.593PheAsn: 1.593 ± 0.045
1.66PhePro: 1.66 ± 0.05
1.039PheGln: 1.039 ± 0.032
2.315PheArg: 2.315 ± 0.049
3.576PheSer: 3.576 ± 0.06
2.534PheThr: 2.534 ± 0.051
2.279PheVal: 2.279 ± 0.05
0.586PheTrp: 0.586 ± 0.025
1.266PheTyr: 1.266 ± 0.038
0.0PheXaa: 0.0 ± 0.0
Gly
6.031GlyAla: 6.031 ± 0.1
1.03GlyCys: 1.03 ± 0.027
3.657GlyAsp: 3.657 ± 0.063
4.489GlyGlu: 4.489 ± 0.075
3.236GlyPhe: 3.236 ± 0.067
5.488GlyGly: 5.488 ± 0.099
1.846GlyHis: 1.846 ± 0.042
5.181GlyIle: 5.181 ± 0.082
3.982GlyLys: 3.982 ± 0.068
7.672GlyLeu: 7.672 ± 0.094
2.391GlyMet: 2.391 ± 0.048
2.848GlyAsn: 2.848 ± 0.068
2.267GlyPro: 2.267 ± 0.054
3.245GlyGln: 3.245 ± 0.067
4.003GlyArg: 4.003 ± 0.063
4.651GlySer: 4.651 ± 0.085
3.946GlyThr: 3.946 ± 0.079
5.437GlyVal: 5.437 ± 0.072
1.276GlyTrp: 1.276 ± 0.035
2.735GlyTyr: 2.735 ± 0.06
0.0GlyXaa: 0.0 ± 0.0
His
1.812HisAla: 1.812 ± 0.04
0.396HisCys: 0.396 ± 0.022
1.127HisAsp: 1.127 ± 0.033
1.037HisGlu: 1.037 ± 0.032
1.029HisPhe: 1.029 ± 0.03
1.704HisGly: 1.704 ± 0.042
0.798HisHis: 0.798 ± 0.032
1.28HisIle: 1.28 ± 0.039
0.721HisLys: 0.721 ± 0.025
2.394HisLeu: 2.394 ± 0.048
0.587HisMet: 0.587 ± 0.023
0.799HisAsn: 0.799 ± 0.028
1.52HisPro: 1.52 ± 0.044
1.416HisGln: 1.416 ± 0.043
1.383HisArg: 1.383 ± 0.042
1.383HisSer: 1.383 ± 0.035
1.132HisThr: 1.132 ± 0.033
1.154HisVal: 1.154 ± 0.034
0.543HisTrp: 0.543 ± 0.026
0.926HisTyr: 0.926 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
6.15IleAla: 6.15 ± 0.095
0.675IleCys: 0.675 ± 0.027
3.415IleAsp: 3.415 ± 0.062
3.148IleGlu: 3.148 ± 0.058
2.22IlePhe: 2.22 ± 0.055
4.406IleGly: 4.406 ± 0.073
1.191IleHis: 1.191 ± 0.04
3.613IleIle: 3.613 ± 0.078
2.116IleLys: 2.116 ± 0.051
5.357IleLeu: 5.357 ± 0.083
1.275IleMet: 1.275 ± 0.042
2.558IleAsn: 2.558 ± 0.057
2.852IlePro: 2.852 ± 0.05
1.708IleGln: 1.708 ± 0.041
3.575IleArg: 3.575 ± 0.053
4.478IleSer: 4.478 ± 0.069
3.943IleThr: 3.943 ± 0.067
3.541IleVal: 3.541 ± 0.06
0.605IleTrp: 0.605 ± 0.026
1.557IleTyr: 1.557 ± 0.04
0.0IleXaa: 0.0 ± 0.0
Lys
3.75LysAla: 3.75 ± 0.081
0.243LysCys: 0.243 ± 0.017
1.977LysAsp: 1.977 ± 0.055
2.191LysGlu: 2.191 ± 0.053
1.078LysPhe: 1.078 ± 0.033
2.72LysGly: 2.72 ± 0.059
0.818LysHis: 0.818 ± 0.032
2.463LysIle: 2.463 ± 0.054
2.342LysLys: 2.342 ± 0.054
3.765LysLeu: 3.765 ± 0.066
1.169LysMet: 1.169 ± 0.039
1.759LysAsn: 1.759 ± 0.05
1.867LysPro: 1.867 ± 0.043
1.916LysGln: 1.916 ± 0.041
2.233LysArg: 2.233 ± 0.048
2.326LysSer: 2.326 ± 0.05
2.515LysThr: 2.515 ± 0.04
2.713LysVal: 2.713 ± 0.06
0.387LysTrp: 0.387 ± 0.022
1.146LysTyr: 1.146 ± 0.037
0.0LysXaa: 0.0 ± 0.0
Leu
10.801LeuAla: 10.801 ± 0.133
1.338LeuCys: 1.338 ± 0.039
5.037LeuAsp: 5.037 ± 0.082
5.102LeuGlu: 5.102 ± 0.089
4.34LeuPhe: 4.34 ± 0.074
6.784LeuGly: 6.784 ± 0.098
2.341LeuHis: 2.341 ± 0.054
5.997LeuIle: 5.997 ± 0.089
4.402LeuLys: 4.402 ± 0.084
12.378LeuLeu: 12.378 ± 0.164
2.902LeuMet: 2.902 ± 0.055
4.188LeuAsn: 4.188 ± 0.067
6.183LeuPro: 6.183 ± 0.094
4.939LeuGln: 4.939 ± 0.079
6.367LeuArg: 6.367 ± 0.094
8.642LeuSer: 8.642 ± 0.114
6.847LeuThr: 6.847 ± 0.094
6.717LeuVal: 6.717 ± 0.097
1.374LeuTrp: 1.374 ± 0.046
2.637LeuTyr: 2.637 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
2.767MetAla: 2.767 ± 0.047
0.171MetCys: 0.171 ± 0.013
1.183MetAsp: 1.183 ± 0.037
1.161MetGlu: 1.161 ± 0.041
0.795MetPhe: 0.795 ± 0.028
1.785MetGly: 1.785 ± 0.042
0.499MetHis: 0.499 ± 0.023
1.539MetIle: 1.539 ± 0.038
1.347MetLys: 1.347 ± 0.039
2.916MetLeu: 2.916 ± 0.056
0.878MetMet: 0.878 ± 0.028
1.047MetAsn: 1.047 ± 0.033
1.265MetPro: 1.265 ± 0.041
1.225MetGln: 1.225 ± 0.028
1.367MetArg: 1.367 ± 0.037
1.934MetSer: 1.934 ± 0.042
1.893MetThr: 1.893 ± 0.045
1.755MetVal: 1.755 ± 0.042
0.205MetTrp: 0.205 ± 0.015
0.51MetTyr: 0.51 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.224AsnAla: 3.224 ± 0.068
0.325AsnCys: 0.325 ± 0.02
2.026AsnAsp: 2.026 ± 0.052
1.714AsnGlu: 1.714 ± 0.049
1.299AsnPhe: 1.299 ± 0.037
2.79AsnGly: 2.79 ± 0.059
0.781AsnHis: 0.781 ± 0.025
2.404AsnIle: 2.404 ± 0.056
1.512AsnLys: 1.512 ± 0.044
3.219AsnLeu: 3.219 ± 0.061
0.843AsnMet: 0.843 ± 0.026
1.578AsnAsn: 1.578 ± 0.049
1.971AsnPro: 1.971 ± 0.045
1.531AsnGln: 1.531 ± 0.042
1.962AsnArg: 1.962 ± 0.043
2.146AsnSer: 2.146 ± 0.054
2.184AsnThr: 2.184 ± 0.056
2.225AsnVal: 2.225 ± 0.051
0.486AsnTrp: 0.486 ± 0.023
1.176AsnTyr: 1.176 ± 0.032
0.0AsnXaa: 0.0 ± 0.0
Pro
5.362ProAla: 5.362 ± 0.088
0.422ProCys: 0.422 ± 0.022
2.912ProAsp: 2.912 ± 0.053
3.852ProGlu: 3.852 ± 0.066
1.813ProPhe: 1.813 ± 0.045
4.07ProGly: 4.07 ± 0.066
1.069ProHis: 1.069 ± 0.034
1.456ProIle: 1.456 ± 0.044
1.309ProLys: 1.309 ± 0.039
5.223ProLeu: 5.223 ± 0.074
1.075ProMet: 1.075 ± 0.033
1.008ProAsn: 1.008 ± 0.035
1.857ProPro: 1.857 ± 0.05
2.328ProGln: 2.328 ± 0.053
2.074ProArg: 2.074 ± 0.054
2.357ProSer: 2.357 ± 0.052
1.789ProThr: 1.789 ± 0.046
4.565ProVal: 4.565 ± 0.078
0.714ProTrp: 0.714 ± 0.026
1.206ProTyr: 1.206 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
4.767GlnAla: 4.767 ± 0.089
0.44GlnCys: 0.44 ± 0.025
1.875GlnAsp: 1.875 ± 0.044
2.22GlnGlu: 2.22 ± 0.047
1.444GlnPhe: 1.444 ± 0.037
3.43GlnGly: 3.43 ± 0.071
1.326GlnHis: 1.326 ± 0.037
2.23GlnIle: 2.23 ± 0.048
1.779GlnLys: 1.779 ± 0.043
5.356GlnLeu: 5.356 ± 0.088
1.183GlnMet: 1.183 ± 0.034
1.387GlnAsn: 1.387 ± 0.038
2.356GlnPro: 2.356 ± 0.056
4.164GlnGln: 4.164 ± 0.118
3.199GlnArg: 3.199 ± 0.058
2.704GlnSer: 2.704 ± 0.061
2.28GlnThr: 2.28 ± 0.057
3.142GlnVal: 3.142 ± 0.066
0.783GlnTrp: 0.783 ± 0.031
1.258GlnTyr: 1.258 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
4.407ArgAla: 4.407 ± 0.067
0.611ArgCys: 0.611 ± 0.024
3.007ArgAsp: 3.007 ± 0.061
3.911ArgGlu: 3.911 ± 0.065
2.596ArgPhe: 2.596 ± 0.055
3.613ArgGly: 3.613 ± 0.06
1.796ArgHis: 1.796 ± 0.04
3.503ArgIle: 3.503 ± 0.06
2.507ArgLys: 2.507 ± 0.053
6.669ArgLeu: 6.669 ± 0.114
1.516ArgMet: 1.516 ± 0.041
2.043ArgAsn: 2.043 ± 0.044
2.401ArgPro: 2.401 ± 0.057
4.036ArgGln: 4.036 ± 0.076
3.694ArgArg: 3.694 ± 0.077
2.914ArgSer: 2.914 ± 0.056
2.671ArgThr: 2.671 ± 0.061
3.695ArgVal: 3.695 ± 0.062
0.976ArgTrp: 0.976 ± 0.029
2.312ArgTyr: 2.312 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
6.47SerAla: 6.47 ± 0.095
0.643SerCys: 0.643 ± 0.028
3.574SerAsp: 3.574 ± 0.058
3.546SerGlu: 3.546 ± 0.063
2.444SerPhe: 2.444 ± 0.054
6.116SerGly: 6.116 ± 0.101
1.606SerHis: 1.606 ± 0.039
2.86SerIle: 2.86 ± 0.064
1.888SerLys: 1.888 ± 0.044
7.788SerLeu: 7.788 ± 0.086
1.53SerMet: 1.53 ± 0.04
1.7SerAsn: 1.7 ± 0.049
3.12SerPro: 3.12 ± 0.053
2.906SerGln: 2.906 ± 0.062
3.937SerArg: 3.937 ± 0.061
4.071SerSer: 4.071 ± 0.092
3.016SerThr: 3.016 ± 0.064
4.866SerVal: 4.866 ± 0.077
0.939SerTrp: 0.939 ± 0.035
1.752SerTyr: 1.752 ± 0.042
0.0SerXaa: 0.0 ± 0.0
Thr
5.366ThrAla: 5.366 ± 0.085
0.522ThrCys: 0.522 ± 0.025
3.03ThrAsp: 3.03 ± 0.059
3.026ThrGlu: 3.026 ± 0.06
2.053ThrPhe: 2.053 ± 0.052
5.349ThrGly: 5.349 ± 0.088
1.254ThrHis: 1.254 ± 0.032
2.702ThrIle: 2.702 ± 0.066
1.279ThrLys: 1.279 ± 0.033
7.768ThrLeu: 7.768 ± 0.102
0.995ThrMet: 0.995 ± 0.032
1.395ThrAsn: 1.395 ± 0.036
3.345ThrPro: 3.345 ± 0.057
1.957ThrGln: 1.957 ± 0.049
3.456ThrArg: 3.456 ± 0.062
3.109ThrSer: 3.109 ± 0.07
3.078ThrThr: 3.078 ± 0.066
4.013ThrVal: 4.013 ± 0.074
0.665ThrTrp: 0.665 ± 0.027
1.281ThrTyr: 1.281 ± 0.037
0.0ThrXaa: 0.0 ± 0.0
Val
6.63ValAla: 6.63 ± 0.088
0.803ValCys: 0.803 ± 0.032
3.204ValAsp: 3.204 ± 0.06
3.013ValGlu: 3.013 ± 0.057
2.53ValPhe: 2.53 ± 0.055
4.084ValGly: 4.084 ± 0.067
1.216ValHis: 1.216 ± 0.039
4.982ValIle: 4.982 ± 0.067
2.687ValLys: 2.687 ± 0.056
7.131ValLeu: 7.131 ± 0.088
2.078ValMet: 2.078 ± 0.05
2.6ValAsn: 2.6 ± 0.056
3.089ValPro: 3.089 ± 0.055
2.185ValGln: 2.185 ± 0.047
3.855ValArg: 3.855 ± 0.065
5.308ValSer: 5.308 ± 0.076
4.642ValThr: 4.642 ± 0.072
5.0ValVal: 5.0 ± 0.078
0.914ValTrp: 0.914 ± 0.032
1.626ValTyr: 1.626 ± 0.039
0.0ValXaa: 0.0 ± 0.0
Trp
0.832TrpAla: 0.832 ± 0.029
0.184TrpCys: 0.184 ± 0.016
0.576TrpAsp: 0.576 ± 0.025
0.502TrpGlu: 0.502 ± 0.023
0.656TrpPhe: 0.656 ± 0.025
0.844TrpGly: 0.844 ± 0.032
0.448TrpHis: 0.448 ± 0.022
0.763TrpIle: 0.763 ± 0.026
0.528TrpLys: 0.528 ± 0.023
2.216TrpLeu: 2.216 ± 0.049
0.394TrpMet: 0.394 ± 0.019
0.467TrpAsn: 0.467 ± 0.023
0.658TrpPro: 0.658 ± 0.027
1.248TrpGln: 1.248 ± 0.039
0.97TrpArg: 0.97 ± 0.035
0.796TrpSer: 0.796 ± 0.032
0.551TrpThr: 0.551 ± 0.023
0.85TrpVal: 0.85 ± 0.028
0.217TrpTrp: 0.217 ± 0.016
0.415TrpTyr: 0.415 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.313TyrAla: 2.313 ± 0.052
0.42TyrCys: 0.42 ± 0.02
1.555TyrAsp: 1.555 ± 0.044
1.177TyrGlu: 1.177 ± 0.035
1.158TyrPhe: 1.158 ± 0.036
2.178TyrGly: 2.178 ± 0.057
0.79TyrHis: 0.79 ± 0.027
1.389TyrIle: 1.389 ± 0.042
0.845TyrLys: 0.845 ± 0.03
3.223TyrLeu: 3.223 ± 0.054
0.602TyrMet: 0.602 ± 0.025
0.973TyrAsn: 0.973 ± 0.036
1.481TyrPro: 1.481 ± 0.04
1.813TyrGln: 1.813 ± 0.051
2.11TyrArg: 2.11 ± 0.049
1.93TyrSer: 1.93 ± 0.05
1.57TyrThr: 1.57 ± 0.053
1.504TyrVal: 1.504 ± 0.041
0.426TyrTrp: 0.426 ± 0.02
0.904TyrTyr: 0.904 ± 0.035
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3337 proteins (1003587 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski