Amino acid dipepetide frequency for Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) (Verticillium wilt)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.894AlaAla: 11.894 ± 0.09	1.182AlaCys: 1.182 ± 0.02	5.058AlaAsp: 5.058 ± 0.034	5.653AlaGlu: 5.653 ± 0.039	3.284AlaPhe: 3.284 ± 0.03	6.873AlaGly: 6.873 ± 0.052	2.052AlaHis: 2.052 ± 0.021	4.12AlaIle: 4.12 ± 0.035	4.237AlaLys: 4.237 ± 0.036	8.386AlaLeu: 8.386 ± 0.05	2.201AlaMet: 2.201 ± 0.023	3.099AlaAsn: 3.099 ± 0.028	5.933AlaPro: 5.933 ± 0.052	3.794AlaGln: 3.794 ± 0.04	5.859AlaArg: 5.859 ± 0.039	8.05AlaSer: 8.05 ± 0.047	5.842AlaThr: 5.842 ± 0.037	6.134AlaVal: 6.134 ± 0.041	1.337AlaTrp: 1.337 ± 0.018	2.176AlaTyr: 2.176 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.008CysAla: 1.008 ± 0.018	0.257CysCys: 0.257 ± 0.01	0.679CysAsp: 0.679 ± 0.013	0.581CysGlu: 0.581 ± 0.012	0.509CysPhe: 0.509 ± 0.01	0.979CysGly: 0.979 ± 0.024	0.348CysHis: 0.348 ± 0.009	0.634CysIle: 0.634 ± 0.013	0.468CysLys: 0.468 ± 0.013	1.207CysLeu: 1.207 ± 0.019	0.263CysMet: 0.263 ± 0.008	0.419CysAsn: 0.419 ± 0.011	0.676CysPro: 0.676 ± 0.015	0.442CysGln: 0.442 ± 0.011	0.803CysArg: 0.803 ± 0.015	0.865CysSer: 0.865 ± 0.015	0.694CysThr: 0.694 ± 0.016	0.803CysVal: 0.803 ± 0.022	0.19CysTrp: 0.19 ± 0.007	0.32CysTyr: 0.32 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.7AspAla: 5.7 ± 0.04	0.625AspCys: 0.625 ± 0.014	4.983AspAsp: 4.983 ± 0.052	4.686AspGlu: 4.686 ± 0.041	2.215AspPhe: 2.215 ± 0.023	4.529AspGly: 4.529 ± 0.038	1.297AspHis: 1.297 ± 0.016	2.746AspIle: 2.746 ± 0.024	2.419AspLys: 2.419 ± 0.022	5.06AspLeu: 5.06 ± 0.038	1.364AspMet: 1.364 ± 0.016	1.823AspAsn: 1.823 ± 0.022	3.331AspPro: 3.331 ± 0.029	1.869AspGln: 1.869 ± 0.021	3.219AspArg: 3.219 ± 0.032	3.92AspSer: 3.92 ± 0.034	2.936AspThr: 2.936 ± 0.026	3.962AspVal: 3.962 ± 0.032	0.905AspTrp: 0.905 ± 0.013	1.514AspTyr: 1.514 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	6.097GluAla: 6.097 ± 0.043	0.588GluCys: 0.588 ± 0.012	4.203GluAsp: 4.203 ± 0.039	4.984GluGlu: 4.984 ± 0.059	1.753GluPhe: 1.753 ± 0.02	3.836GluGly: 3.836 ± 0.03	1.365GluHis: 1.365 ± 0.022	2.563GluIle: 2.563 ± 0.026	3.237GluLys: 3.237 ± 0.032	4.972GluLeu: 4.972 ± 0.036	1.382GluMet: 1.382 ± 0.019	1.95GluAsn: 1.95 ± 0.022	3.019GluPro: 3.019 ± 0.056	2.362GluGln: 2.362 ± 0.024	3.924GluArg: 3.924 ± 0.035	3.894GluSer: 3.894 ± 0.032	3.521GluThr: 3.521 ± 0.033	3.554GluVal: 3.554 ± 0.03	0.8GluTrp: 0.8 ± 0.013	1.5GluTyr: 1.5 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.253PheAla: 3.253 ± 0.03	0.539PheCys: 0.539 ± 0.012	2.326PheAsp: 2.326 ± 0.023	2.075PheGlu: 2.075 ± 0.021	1.579PhePhe: 1.579 ± 0.024	2.878PheGly: 2.878 ± 0.03	0.854PheHis: 0.854 ± 0.013	1.616PheIle: 1.616 ± 0.02	1.366PheLys: 1.366 ± 0.018	3.25PheLeu: 3.25 ± 0.031	0.759PheMet: 0.759 ± 0.012	1.325PheAsn: 1.325 ± 0.019	1.826PhePro: 1.826 ± 0.019	1.301PheGln: 1.301 ± 0.015	1.947PheArg: 1.947 ± 0.021	2.686PheSer: 2.686 ± 0.024	2.035PheThr: 2.035 ± 0.024	2.414PheVal: 2.414 ± 0.027	0.631PheTrp: 0.631 ± 0.013	0.987PheTyr: 0.987 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	6.293GlyAla: 6.293 ± 0.048	0.896GlyCys: 0.896 ± 0.017	3.981GlyAsp: 3.981 ± 0.034	3.65GlyGlu: 3.65 ± 0.028	2.817GlyPhe: 2.817 ± 0.033	6.615GlyGly: 6.615 ± 0.068	1.854GlyHis: 1.854 ± 0.022	3.306GlyIle: 3.306 ± 0.031	3.275GlyLys: 3.275 ± 0.034	6.253GlyLeu: 6.253 ± 0.036	1.617GlyMet: 1.617 ± 0.021	2.535GlyAsn: 2.535 ± 0.032	3.746GlyPro: 3.746 ± 0.037	2.758GlyGln: 2.758 ± 0.033	4.652GlyArg: 4.652 ± 0.036	5.812GlySer: 5.812 ± 0.041	4.136GlyThr: 4.136 ± 0.035	4.599GlyVal: 4.599 ± 0.041	1.177GlyTrp: 1.177 ± 0.019	1.991GlyTyr: 1.991 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.159HisAla: 2.159 ± 0.023	0.328HisCys: 0.328 ± 0.009	1.474HisAsp: 1.474 ± 0.018	1.352HisGlu: 1.352 ± 0.015	0.889HisPhe: 0.889 ± 0.012	1.907HisGly: 1.907 ± 0.024	0.907HisHis: 0.907 ± 0.016	1.122HisIle: 1.122 ± 0.016	0.876HisLys: 0.876 ± 0.014	2.222HisLeu: 2.222 ± 0.023	0.534HisMet: 0.534 ± 0.011	0.804HisAsn: 0.804 ± 0.013	1.637HisPro: 1.637 ± 0.02	1.057HisGln: 1.057 ± 0.019	1.633HisArg: 1.633 ± 0.023	1.686HisSer: 1.686 ± 0.023	1.242HisThr: 1.242 ± 0.015	1.591HisVal: 1.591 ± 0.017	0.343HisTrp: 0.343 ± 0.008	0.653HisTyr: 0.653 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.034IleAla: 4.034 ± 0.032	0.656IleCys: 0.656 ± 0.016	2.712IleAsp: 2.712 ± 0.023	2.592IleGlu: 2.592 ± 0.025	1.752IlePhe: 1.752 ± 0.021	2.956IleGly: 2.956 ± 0.033	1.078IleHis: 1.078 ± 0.016	2.199IleIle: 2.199 ± 0.028	1.919IleLys: 1.919 ± 0.023	4.015IleLeu: 4.015 ± 0.038	0.989IleMet: 0.989 ± 0.016	1.599IleAsn: 1.599 ± 0.018	2.652IlePro: 2.652 ± 0.03	1.629IleGln: 1.629 ± 0.019	2.642IleArg: 2.642 ± 0.025	3.266IleSer: 3.266 ± 0.025	2.55IleThr: 2.55 ± 0.027	3.041IleVal: 3.041 ± 0.028	0.663IleTrp: 0.663 ± 0.013	1.173IleTyr: 1.173 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.445LysAla: 4.445 ± 0.041	0.455LysCys: 0.455 ± 0.01	2.6LysAsp: 2.6 ± 0.027	2.917LysGlu: 2.917 ± 0.031	1.314LysPhe: 1.314 ± 0.016	2.872LysGly: 2.872 ± 0.031	1.059LysHis: 1.059 ± 0.016	1.947LysIle: 1.947 ± 0.022	3.205LysLys: 3.205 ± 0.069	3.736LysLeu: 3.736 ± 0.037	0.948LysMet: 0.948 ± 0.014	1.559LysAsn: 1.559 ± 0.018	2.664LysPro: 2.664 ± 0.026	1.711LysGln: 1.711 ± 0.021	3.223LysArg: 3.223 ± 0.03	3.104LysSer: 3.104 ± 0.032	2.844LysThr: 2.844 ± 0.027	2.659LysVal: 2.659 ± 0.025	0.609LysTrp: 0.609 ± 0.011	1.177LysTyr: 1.177 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.616LeuAla: 8.616 ± 0.046	1.135LeuCys: 1.135 ± 0.016	5.17LeuAsp: 5.17 ± 0.039	5.22LeuGlu: 5.22 ± 0.04	3.156LeuPhe: 3.156 ± 0.032	6.019LeuGly: 6.019 ± 0.039	2.207LeuHis: 2.207 ± 0.024	3.508LeuIle: 3.508 ± 0.034	3.766LeuLys: 3.766 ± 0.035	8.083LeuLeu: 8.083 ± 0.056	1.746LeuMet: 1.746 ± 0.019	2.84LeuAsn: 2.84 ± 0.024	5.552LeuPro: 5.552 ± 0.04	3.625LeuGln: 3.625 ± 0.029	5.909LeuArg: 5.909 ± 0.037	6.745LeuSer: 6.745 ± 0.041	4.878LeuThr: 4.878 ± 0.035	5.57LeuVal: 5.57 ± 0.038	1.177LeuTrp: 1.177 ± 0.015	2.138LeuTyr: 2.138 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.496MetAla: 2.496 ± 0.024	0.24MetCys: 0.24 ± 0.007	1.254MetAsp: 1.254 ± 0.016	1.173MetGlu: 1.173 ± 0.017	0.723MetPhe: 0.723 ± 0.012	1.508MetGly: 1.508 ± 0.019	0.498MetHis: 0.498 ± 0.009	0.907MetIle: 0.907 ± 0.014	0.948MetLys: 0.948 ± 0.012	1.815MetLeu: 1.815 ± 0.021	0.586MetMet: 0.586 ± 0.011	0.754MetAsn: 0.754 ± 0.012	1.372MetPro: 1.372 ± 0.019	0.814MetGln: 0.814 ± 0.017	1.337MetArg: 1.337 ± 0.019	1.84MetSer: 1.84 ± 0.017	1.382MetThr: 1.382 ± 0.017	1.326MetVal: 1.326 ± 0.016	0.261MetTrp: 0.261 ± 0.008	0.508MetTyr: 0.508 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.094AsnAla: 3.094 ± 0.027	0.413AsnCys: 0.413 ± 0.011	1.927AsnAsp: 1.927 ± 0.02	1.826AsnGlu: 1.826 ± 0.019	1.247AsnPhe: 1.247 ± 0.014	2.949AsnGly: 2.949 ± 0.031	0.797AsnHis: 0.797 ± 0.013	1.748AsnIle: 1.748 ± 0.02	1.448AsnLys: 1.448 ± 0.019	2.989AsnLeu: 2.989 ± 0.026	0.812AsnMet: 0.812 ± 0.013	1.373AsnAsn: 1.373 ± 0.025	2.294AsnPro: 2.294 ± 0.021	1.177AsnGln: 1.177 ± 0.017	1.854AsnArg: 1.854 ± 0.021	2.341AsnSer: 2.341 ± 0.024	2.03AsnThr: 2.03 ± 0.023	2.244AsnVal: 2.244 ± 0.023	0.512AsnTrp: 0.512 ± 0.011	0.924AsnTyr: 0.924 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	6.422ProAla: 6.422 ± 0.059	0.572ProCys: 0.572 ± 0.016	3.359ProAsp: 3.359 ± 0.03	3.844ProGlu: 3.844 ± 0.04	2.009ProPhe: 2.009 ± 0.02	4.364ProGly: 4.364 ± 0.04	1.372ProHis: 1.372 ± 0.019	2.303ProIle: 2.303 ± 0.025	2.546ProLys: 2.546 ± 0.027	4.863ProLeu: 4.863 ± 0.034	1.126ProMet: 1.126 ± 0.017	2.021ProAsn: 2.021 ± 0.023	5.51ProPro: 5.51 ± 0.068	2.526ProGln: 2.526 ± 0.035	3.809ProArg: 3.809 ± 0.034	6.053ProSer: 6.053 ± 0.058	4.109ProThr: 4.109 ± 0.037	3.866ProVal: 3.866 ± 0.037	0.771ProTrp: 0.771 ± 0.013	1.413ProTyr: 1.413 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.85GlnAla: 3.85 ± 0.034	0.442GlnCys: 0.442 ± 0.011	2.109GlnAsp: 2.109 ± 0.023	2.179GlnGlu: 2.179 ± 0.022	1.163GlnPhe: 1.163 ± 0.017	2.602GlnGly: 2.602 ± 0.032	1.187GlnHis: 1.187 ± 0.022	1.663GlnIle: 1.663 ± 0.017	1.813GlnLys: 1.813 ± 0.022	3.303GlnLeu: 3.303 ± 0.031	0.877GlnMet: 0.877 ± 0.015	1.357GlnAsn: 1.357 ± 0.019	2.691GlnPro: 2.691 ± 0.031	2.932GlnGln: 2.932 ± 0.073	2.692GlnArg: 2.692 ± 0.022	2.919GlnSer: 2.919 ± 0.03	2.332GlnThr: 2.332 ± 0.022	2.208GlnVal: 2.208 ± 0.022	0.566GlnTrp: 0.566 ± 0.01	1.084GlnTyr: 1.084 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.517ArgAla: 5.517 ± 0.033	0.771ArgCys: 0.771 ± 0.014	3.728ArgAsp: 3.728 ± 0.037	3.795ArgGlu: 3.795 ± 0.033	2.147ArgPhe: 2.147 ± 0.02	4.149ArgGly: 4.149 ± 0.037	1.793ArgHis: 1.793 ± 0.02	2.747ArgIle: 2.747 ± 0.023	3.26ArgLys: 3.26 ± 0.031	5.566ArgLeu: 5.566 ± 0.036	1.372ArgMet: 1.372 ± 0.019	2.174ArgAsn: 2.174 ± 0.019	3.966ArgPro: 3.966 ± 0.032	2.849ArgGln: 2.849 ± 0.027	5.735ArgArg: 5.735 ± 0.055	4.83ArgSer: 4.83 ± 0.045	3.47ArgThr: 3.47 ± 0.024	3.501ArgVal: 3.501 ± 0.024	0.996ArgTrp: 0.996 ± 0.014	1.593ArgTyr: 1.593 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.048SerAla: 7.048 ± 0.044	0.858SerCys: 0.858 ± 0.013	4.163SerAsp: 4.163 ± 0.033	3.792SerGlu: 3.792 ± 0.03	2.862SerPhe: 2.862 ± 0.025	5.568SerGly: 5.568 ± 0.041	1.912SerHis: 1.912 ± 0.022	3.504SerIle: 3.504 ± 0.033	3.291SerLys: 3.291 ± 0.034	6.785SerLeu: 6.785 ± 0.043	1.673SerMet: 1.673 ± 0.02	2.693SerAsn: 2.693 ± 0.027	5.489SerPro: 5.489 ± 0.055	3.097SerGln: 3.097 ± 0.031	5.11SerArg: 5.11 ± 0.045	8.333SerSer: 8.333 ± 0.078	5.293SerThr: 5.293 ± 0.042	4.472SerVal: 4.472 ± 0.03	1.112SerTrp: 1.112 ± 0.016	1.87SerTyr: 1.87 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.843ThrAla: 5.843 ± 0.037	0.768ThrCys: 0.768 ± 0.023	2.932ThrAsp: 2.932 ± 0.024	3.019ThrGlu: 3.019 ± 0.029	2.119ThrPhe: 2.119 ± 0.02	4.234ThrGly: 4.234 ± 0.037	1.309ThrHis: 1.309 ± 0.017	2.86ThrIle: 2.86 ± 0.023	2.497ThrLys: 2.497 ± 0.028	5.145ThrLeu: 5.145 ± 0.034	1.218ThrMet: 1.218 ± 0.015	2.006ThrAsn: 2.006 ± 0.019	4.588ThrPro: 4.588 ± 0.043	2.12ThrGln: 2.12 ± 0.021	3.376ThrArg: 3.376 ± 0.03	5.207ThrSer: 5.207 ± 0.039	4.455ThrThr: 4.455 ± 0.045	3.754ThrVal: 3.754 ± 0.033	0.893ThrTrp: 0.893 ± 0.013	1.491ThrTyr: 1.491 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.007ValAla: 6.007 ± 0.042	0.849ValCys: 0.849 ± 0.018	3.913ValAsp: 3.913 ± 0.03	3.918ValGlu: 3.918 ± 0.034	2.469ValPhe: 2.469 ± 0.026	4.157ValGly: 4.157 ± 0.038	1.424ValHis: 1.424 ± 0.019	2.753ValIle: 2.753 ± 0.026	2.782ValLys: 2.782 ± 0.029	5.696ValLeu: 5.696 ± 0.043	1.343ValMet: 1.343 ± 0.018	2.105ValAsn: 2.105 ± 0.024	3.872ValPro: 3.872 ± 0.035	2.335ValGln: 2.335 ± 0.023	3.694ValArg: 3.694 ± 0.027	4.563ValSer: 4.563 ± 0.032	3.695ValThr: 3.695 ± 0.031	4.511ValVal: 4.511 ± 0.033	0.905ValTrp: 0.905 ± 0.015	1.641ValTyr: 1.641 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.247TrpAla: 1.247 ± 0.018	0.204TrpCys: 0.204 ± 0.006	0.909TrpAsp: 0.909 ± 0.015	0.802TrpGlu: 0.802 ± 0.014	0.553TrpPhe: 0.553 ± 0.012	0.963TrpGly: 0.963 ± 0.017	0.389TrpHis: 0.389 ± 0.01	0.682TrpIle: 0.682 ± 0.013	0.72TrpLys: 0.72 ± 0.011	1.336TrpLeu: 1.336 ± 0.02	0.364TrpMet: 0.364 ± 0.009	0.59TrpAsn: 0.59 ± 0.011	0.664TrpPro: 0.664 ± 0.011	0.596TrpGln: 0.596 ± 0.012	0.988TrpArg: 0.988 ± 0.014	1.043TrpSer: 1.043 ± 0.013	0.936TrpThr: 0.936 ± 0.014	0.875TrpVal: 0.875 ± 0.014	0.281TrpTrp: 0.281 ± 0.008	0.413TrpTyr: 0.413 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.141TyrAla: 2.141 ± 0.019	0.368TyrCys: 0.368 ± 0.01	1.625TyrAsp: 1.625 ± 0.02	1.447TyrGlu: 1.447 ± 0.019	1.086TyrPhe: 1.086 ± 0.017	2.006TyrGly: 2.006 ± 0.025	0.713TyrHis: 0.713 ± 0.013	1.192TyrIle: 1.192 ± 0.016	0.974TyrLys: 0.974 ± 0.017	2.38TyrLeu: 2.38 ± 0.023	0.565TyrMet: 0.565 ± 0.01	0.972TyrAsn: 0.972 ± 0.013	1.376TyrPro: 1.376 ± 0.021	0.974TyrGln: 0.974 ± 0.016	1.553TyrArg: 1.553 ± 0.017	1.766TyrSer: 1.766 ± 0.019	1.457TyrThr: 1.457 ± 0.019	1.548TyrVal: 1.548 ± 0.017	0.425TyrTrp: 0.425 ± 0.011	0.798TyrTyr: 0.798 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10530 proteins (4983248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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