Bos taurus papillomavirus 4 (Bovine papillomavirus 4)

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Xipapillomavirus; Xipapillomavirus 1

Average proteome isoelectric point is 7.04

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P08352|VE8_BPV4 Uncharacterized protein E8 OS=Bos taurus papillomavirus 4 OX=10562 PE=4 SV=1
MM1 pKa = 7.63KK2 pKa = 9.93GQNVTLQDD10 pKa = 3.25IAIEE14 pKa = 4.24LEE16 pKa = 4.3DD17 pKa = 4.44TISPINLHH25 pKa = 6.07CEE27 pKa = 4.02EE28 pKa = 4.83EE29 pKa = 4.44IEE31 pKa = 4.28TEE33 pKa = 4.69EE34 pKa = 4.45VDD36 pKa = 3.83TPNPFAITATCYY48 pKa = 10.59ACEE51 pKa = 3.88QVLRR55 pKa = 11.84LAVVTSTEE63 pKa = 4.71GIHH66 pKa = 6.57QLQQLLFDD74 pKa = 5.02NLFLLCAACSKK85 pKa = 10.58QVFCNRR91 pKa = 11.84RR92 pKa = 11.84PEE94 pKa = 4.16RR95 pKa = 11.84NGPP98 pKa = 3.49

Molecular weight: 10.99 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P08346|VE3_BPV4 Probable protein E3 OS=Bos taurus papillomavirus 4 OX=10562 GN=E3 PE=4 SV=1
MM1 pKa = 6.96YY2 pKa = 10.19LCLEE6 pKa = 4.29SLQKK10 pKa = 10.58SEE12 pKa = 4.92FANQRR17 pKa = 11.84WSLVDD22 pKa = 3.14TSIEE26 pKa = 4.16TFKK29 pKa = 11.23APPEE33 pKa = 3.98NTLKK37 pKa = 10.77KK38 pKa = 9.91RR39 pKa = 11.84GQHH42 pKa = 3.92VTVIYY47 pKa = 9.9DD48 pKa = 3.56QNAMNSMVYY57 pKa = 8.48TLWKK61 pKa = 8.63EE62 pKa = 3.91VYY64 pKa = 10.01YY65 pKa = 10.94VDD67 pKa = 5.17EE68 pKa = 4.57TEE70 pKa = 4.27TWHH73 pKa = 6.09KK74 pKa = 9.6TSSDD78 pKa = 3.38LDD80 pKa = 3.71YY81 pKa = 11.71DD82 pKa = 4.2GIFYY86 pKa = 10.2IDD88 pKa = 3.42NQGNKK93 pKa = 8.64IYY95 pKa = 10.66YY96 pKa = 10.65VNFQDD101 pKa = 5.78DD102 pKa = 3.48AALYY106 pKa = 9.36SNSGMGQVHH115 pKa = 6.57FEE117 pKa = 4.41SKK119 pKa = 10.53VLSPSVTSSLRR130 pKa = 11.84VGSTGGQRR138 pKa = 11.84GTQTGDD144 pKa = 2.82HH145 pKa = 6.16ARR147 pKa = 11.84GRR149 pKa = 11.84SRR151 pKa = 11.84PSPRR155 pKa = 11.84SSRR158 pKa = 11.84DD159 pKa = 2.95ARR161 pKa = 11.84GRR163 pKa = 11.84QQRR166 pKa = 11.84AQSSSRR172 pKa = 11.84SRR174 pKa = 11.84SRR176 pKa = 11.84SRR178 pKa = 11.84SRR180 pKa = 11.84SPTKK184 pKa = 10.42GPHH187 pKa = 5.18SSGRR191 pKa = 11.84DD192 pKa = 3.18TRR194 pKa = 11.84LPSPGRR200 pKa = 11.84PPGGRR205 pKa = 11.84RR206 pKa = 11.84RR207 pKa = 11.84GTPEE211 pKa = 3.79RR212 pKa = 11.84EE213 pKa = 4.05RR214 pKa = 11.84CPGTPTPPTPDD225 pKa = 3.02QVGGRR230 pKa = 11.84SSTPKK235 pKa = 9.6RR236 pKa = 11.84QASSRR241 pKa = 11.84LAQLIDD247 pKa = 3.43AAYY250 pKa = 9.68DD251 pKa = 3.66PPVLLLQGAANTLKK265 pKa = 10.47CFRR268 pKa = 11.84RR269 pKa = 11.84RR270 pKa = 11.84ATQAHH275 pKa = 5.24PHH277 pKa = 6.58KK278 pKa = 9.05FLCMSTSWTWVSKK291 pKa = 9.41TSPLKK296 pKa = 10.3SGHH299 pKa = 6.3RR300 pKa = 11.84MLIAFSNSEE309 pKa = 3.65QRR311 pKa = 11.84NCFLASVRR319 pKa = 11.84LPKK322 pKa = 10.5GVSAVKK328 pKa = 10.33GALDD332 pKa = 3.52GLL334 pKa = 4.31

Molecular weight: 37.16 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11

0

11

2416

48

608

219.6

24.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.96 ± 0.502

2.649 ± 0.545

5.877 ± 0.468

5.422 ± 0.619

4.636 ± 0.574

6.25 ± 0.701

2.152 ± 0.178

4.346 ± 0.589

5.132 ± 0.586

8.982 ± 1.186

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.945 ± 0.207

4.222 ± 0.469

6.333 ± 0.737

4.967 ± 0.34

6.581 ± 0.933

7.326 ± 0.978

6.705 ± 0.419

5.712 ± 0.415

1.697 ± 0.277

3.104 ± 0.466
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski