Amino acid dipepetide frequency for Colius striatus (Speckled mousebird)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.66AlaAla: 5.66 ± 0.068	1.291AlaCys: 1.291 ± 0.021	2.971AlaAsp: 2.971 ± 0.034	4.615AlaGlu: 4.615 ± 0.048	2.577AlaPhe: 2.577 ± 0.035	3.782AlaGly: 3.782 ± 0.048	1.367AlaHis: 1.367 ± 0.022	3.108AlaIle: 3.108 ± 0.038	3.786AlaLys: 3.786 ± 0.047	6.451AlaLeu: 6.451 ± 0.062	1.542AlaMet: 1.542 ± 0.024	2.295AlaAsn: 2.295 ± 0.028	2.818AlaPro: 2.818 ± 0.04	2.755AlaGln: 2.755 ± 0.037	2.909AlaArg: 2.909 ± 0.037	5.134AlaSer: 5.134 ± 0.054	3.378AlaThr: 3.378 ± 0.036	4.817AlaVal: 4.817 ± 0.046	0.68AlaTrp: 0.68 ± 0.018	1.644AlaTyr: 1.644 ± 0.03	0.0AlaXaa: 0.0 ± 0.0
Cys	1.179CysAla: 1.179 ± 0.025	0.65CysCys: 0.65 ± 0.021	1.023CysAsp: 1.023 ± 0.024	1.283CysGlu: 1.283 ± 0.024	0.905CysPhe: 0.905 ± 0.019	1.418CysGly: 1.418 ± 0.029	0.651CysHis: 0.651 ± 0.017	1.171CysIle: 1.171 ± 0.023	1.346CysLys: 1.346 ± 0.024	2.144CysLeu: 2.144 ± 0.035	0.436CysMet: 0.436 ± 0.012	0.931CysAsn: 0.931 ± 0.021	1.234CysPro: 1.234 ± 0.032	1.079CysGln: 1.079 ± 0.025	1.175CysArg: 1.175 ± 0.023	1.969CysSer: 1.969 ± 0.035	1.189CysThr: 1.189 ± 0.023	1.346CysVal: 1.346 ± 0.032	0.283CysTrp: 0.283 ± 0.011	0.675CysTyr: 0.675 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	2.87AspAla: 2.87 ± 0.034	1.107AspCys: 1.107 ± 0.022	2.882AspAsp: 2.882 ± 0.039	3.697AspGlu: 3.697 ± 0.042	2.275AspPhe: 2.275 ± 0.029	3.262AspGly: 3.262 ± 0.049	1.159AspHis: 1.159 ± 0.019	2.961AspIle: 2.961 ± 0.037	2.827AspLys: 2.827 ± 0.033	5.06AspLeu: 5.06 ± 0.046	1.181AspMet: 1.181 ± 0.022	1.986AspAsn: 1.986 ± 0.032	2.627AspPro: 2.627 ± 0.035	1.865AspGln: 1.865 ± 0.024	2.377AspArg: 2.377 ± 0.031	4.15AspSer: 4.15 ± 0.041	2.568AspThr: 2.568 ± 0.037	3.308AspVal: 3.308 ± 0.048	0.647AspTrp: 0.647 ± 0.017	1.704AspTyr: 1.704 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	4.741GluAla: 4.741 ± 0.053	1.301GluCys: 1.301 ± 0.032	4.466GluAsp: 4.466 ± 0.047	7.925GluGlu: 7.925 ± 0.113	2.268GluPhe: 2.268 ± 0.024	3.898GluGly: 3.898 ± 0.042	1.618GluHis: 1.618 ± 0.023	3.55GluIle: 3.55 ± 0.038	5.805GluLys: 5.805 ± 0.077	6.383GluLeu: 6.383 ± 0.072	1.797GluMet: 1.797 ± 0.028	3.477GluAsn: 3.477 ± 0.038	2.556GluPro: 2.556 ± 0.035	3.299GluGln: 3.299 ± 0.045	4.075GluArg: 4.075 ± 0.068	4.573GluSer: 4.573 ± 0.052	3.517GluThr: 3.517 ± 0.042	4.267GluVal: 4.267 ± 0.045	0.746GluTrp: 0.746 ± 0.016	1.856GluTyr: 1.856 ± 0.028	0.001GluXaa: 0.001 ± 0.001
Phe	2.169PheAla: 2.169 ± 0.028	0.999PheCys: 0.999 ± 0.022	1.87PheAsp: 1.87 ± 0.028	2.194PheGlu: 2.194 ± 0.028	1.836PhePhe: 1.836 ± 0.03	2.301PheGly: 2.301 ± 0.035	1.119PheHis: 1.119 ± 0.021	2.121PheIle: 2.121 ± 0.039	2.084PheLys: 2.084 ± 0.027	4.266PheLeu: 4.266 ± 0.043	0.82PheMet: 0.82 ± 0.019	1.565PheAsn: 1.565 ± 0.025	1.957PhePro: 1.957 ± 0.029	1.872PheGln: 1.872 ± 0.025	1.896PheArg: 1.896 ± 0.03	3.505PheSer: 3.505 ± 0.036	2.235PheThr: 2.235 ± 0.033	2.448PheVal: 2.448 ± 0.028	0.538PheTrp: 0.538 ± 0.015	1.367PheTyr: 1.367 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	3.367GlyAla: 3.367 ± 0.046	1.196GlyCys: 1.196 ± 0.023	2.918GlyAsp: 2.918 ± 0.041	3.712GlyGlu: 3.712 ± 0.057	2.457GlyPhe: 2.457 ± 0.035	3.78GlyGly: 3.78 ± 0.068	1.51GlyHis: 1.51 ± 0.027	3.051GlyIle: 3.051 ± 0.041	4.146GlyLys: 4.146 ± 0.054	5.161GlyLeu: 5.161 ± 0.06	1.395GlyMet: 1.395 ± 0.03	2.613GlyAsn: 2.613 ± 0.031	2.676GlyPro: 2.676 ± 0.08	2.51GlyGln: 2.51 ± 0.034	3.072GlyArg: 3.072 ± 0.036	5.021GlySer: 5.021 ± 0.051	3.416GlyThr: 3.416 ± 0.037	3.442GlyVal: 3.442 ± 0.044	0.76GlyTrp: 0.76 ± 0.02	1.866GlyTyr: 1.866 ± 0.032	0.001GlyXaa: 0.001 ± 0.001
His	1.299HisAla: 1.299 ± 0.021	0.717HisCys: 0.717 ± 0.016	0.935HisAsp: 0.935 ± 0.019	1.389HisGlu: 1.389 ± 0.026	1.127HisPhe: 1.127 ± 0.021	1.513HisGly: 1.513 ± 0.025	0.901HisHis: 0.901 ± 0.024	1.379HisIle: 1.379 ± 0.023	1.4HisLys: 1.4 ± 0.027	2.89HisLeu: 2.89 ± 0.033	0.592HisMet: 0.592 ± 0.015	0.988HisAsn: 0.988 ± 0.018	1.453HisPro: 1.453 ± 0.024	1.188HisGln: 1.188 ± 0.026	1.473HisArg: 1.473 ± 0.02	2.227HisSer: 2.227 ± 0.032	1.351HisThr: 1.351 ± 0.027	1.532HisVal: 1.532 ± 0.022	0.357HisTrp: 0.357 ± 0.012	0.88HisTyr: 0.88 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	3.0IleAla: 3.0 ± 0.037	1.237IleCys: 1.237 ± 0.024	2.406IleAsp: 2.406 ± 0.037	2.903IleGlu: 2.903 ± 0.034	2.252IlePhe: 2.252 ± 0.039	2.515IleGly: 2.515 ± 0.032	1.404IleHis: 1.404 ± 0.024	2.823IleIle: 2.823 ± 0.04	3.052IleLys: 3.052 ± 0.03	5.055IleLeu: 5.055 ± 0.05	1.088IleMet: 1.088 ± 0.023	2.207IleAsn: 2.207 ± 0.03	2.909IlePro: 2.909 ± 0.038	2.484IleGln: 2.484 ± 0.033	2.549IleArg: 2.549 ± 0.032	4.139IleSer: 4.139 ± 0.038	2.921IleThr: 2.921 ± 0.038	2.965IleVal: 2.965 ± 0.034	0.6IleTrp: 0.6 ± 0.016	1.645IleTyr: 1.645 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	4.256LysAla: 4.256 ± 0.044	1.219LysCys: 1.219 ± 0.024	3.565LysAsp: 3.565 ± 0.047	5.878LysGlu: 5.878 ± 0.073	1.915LysPhe: 1.915 ± 0.027	3.594LysGly: 3.594 ± 0.065	1.614LysHis: 1.614 ± 0.03	3.253LysIle: 3.253 ± 0.039	5.427LysLys: 5.427 ± 0.081	5.821LysLeu: 5.821 ± 0.051	1.608LysMet: 1.608 ± 0.025	2.781LysAsn: 2.781 ± 0.038	3.086LysPro: 3.086 ± 0.043	3.064LysGln: 3.064 ± 0.041	3.534LysArg: 3.534 ± 0.044	4.424LysSer: 4.424 ± 0.05	3.44LysThr: 3.44 ± 0.039	3.804LysVal: 3.804 ± 0.038	0.699LysTrp: 0.699 ± 0.016	1.915LysTyr: 1.915 ± 0.026	0.001LysXaa: 0.001 ± 0.0
Leu	6.193LeuAla: 6.193 ± 0.056	2.212LeuCys: 2.212 ± 0.034	4.837LeuAsp: 4.837 ± 0.048	7.052LeuGlu: 7.052 ± 0.078	3.647LeuPhe: 3.647 ± 0.045	5.231LeuGly: 5.231 ± 0.054	2.711LeuHis: 2.711 ± 0.035	4.399LeuIle: 4.399 ± 0.05	6.43LeuLys: 6.43 ± 0.063	10.122LeuLeu: 10.122 ± 0.093	2.045LeuMet: 2.045 ± 0.026	3.906LeuAsn: 3.906 ± 0.045	5.353LeuPro: 5.353 ± 0.055	5.686LeuGln: 5.686 ± 0.066	5.154LeuArg: 5.154 ± 0.05	7.938LeuSer: 7.938 ± 0.061	5.081LeuThr: 5.081 ± 0.045	5.52LeuVal: 5.52 ± 0.056	1.107LeuTrp: 1.107 ± 0.02	2.813LeuTyr: 2.813 ± 0.035	0.001LeuXaa: 0.001 ± 0.001
Met	1.639MetAla: 1.639 ± 0.024	0.433MetCys: 0.433 ± 0.012	1.337MetAsp: 1.337 ± 0.022	1.956MetGlu: 1.956 ± 0.028	0.844MetPhe: 0.844 ± 0.017	1.253MetGly: 1.253 ± 0.026	0.536MetHis: 0.536 ± 0.014	0.991MetIle: 0.991 ± 0.018	1.662MetLys: 1.662 ± 0.027	2.067MetLeu: 2.067 ± 0.029	0.625MetMet: 0.625 ± 0.018	1.01MetAsn: 1.01 ± 0.019	1.035MetPro: 1.035 ± 0.022	1.09MetGln: 1.09 ± 0.022	1.077MetArg: 1.077 ± 0.018	1.593MetSer: 1.593 ± 0.021	1.167MetThr: 1.167 ± 0.021	1.467MetVal: 1.467 ± 0.023	0.253MetTrp: 0.253 ± 0.009	0.67MetTyr: 0.67 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.346AsnAla: 2.346 ± 0.032	0.956AsnCys: 0.956 ± 0.021	1.749AsnAsp: 1.749 ± 0.027	2.622AsnGlu: 2.622 ± 0.032	1.651AsnPhe: 1.651 ± 0.025	2.741AsnGly: 2.741 ± 0.043	1.006AsnHis: 1.006 ± 0.021	2.505AsnIle: 2.505 ± 0.031	2.676AsnLys: 2.676 ± 0.035	4.134AsnLeu: 4.134 ± 0.041	1.03AsnMet: 1.03 ± 0.019	1.873AsnAsn: 1.873 ± 0.029	2.298AsnPro: 2.298 ± 0.034	1.732AsnGln: 1.732 ± 0.028	1.996AsnArg: 1.996 ± 0.027	3.489AsnSer: 3.489 ± 0.041	2.272AsnThr: 2.272 ± 0.031	2.575AsnVal: 2.575 ± 0.033	0.537AsnTrp: 0.537 ± 0.015	1.315AsnTyr: 1.315 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	3.501ProAla: 3.501 ± 0.044	1.024ProCys: 1.024 ± 0.033	2.672ProAsp: 2.672 ± 0.028	3.873ProGlu: 3.873 ± 0.045	1.936ProPhe: 1.936 ± 0.03	3.548ProGly: 3.548 ± 0.104	1.246ProHis: 1.246 ± 0.024	1.974ProIle: 1.974 ± 0.028	2.806ProLys: 2.806 ± 0.037	4.651ProLeu: 4.651 ± 0.045	0.932ProMet: 0.932 ± 0.021	1.915ProAsn: 1.915 ± 0.024	3.99ProPro: 3.99 ± 0.073	2.333ProGln: 2.333 ± 0.041	2.411ProArg: 2.411 ± 0.031	4.914ProSer: 4.914 ± 0.057	2.657ProThr: 2.657 ± 0.035	3.68ProVal: 3.68 ± 0.044	0.579ProTrp: 0.579 ± 0.018	1.458ProTyr: 1.458 ± 0.024	0.001ProXaa: 0.001 ± 0.0
Gln	3.065GlnAla: 3.065 ± 0.038	0.956GlnCys: 0.956 ± 0.022	2.282GlnAsp: 2.282 ± 0.027	3.71GlnGlu: 3.71 ± 0.054	1.456GlnPhe: 1.456 ± 0.026	2.476GlnGly: 2.476 ± 0.044	1.337GlnHis: 1.337 ± 0.024	2.245GlnIle: 2.245 ± 0.031	3.234GlnLys: 3.234 ± 0.043	4.754GlnLeu: 4.754 ± 0.052	1.17GlnMet: 1.17 ± 0.023	2.046GlnAsn: 2.046 ± 0.033	2.354GlnPro: 2.354 ± 0.04	3.13GlnGln: 3.13 ± 0.068	2.711GlnArg: 2.711 ± 0.036	3.209GlnSer: 3.209 ± 0.043	2.407GlnThr: 2.407 ± 0.035	2.791GlnVal: 2.791 ± 0.034	0.54GlnTrp: 0.54 ± 0.015	1.335GlnTyr: 1.335 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	3.067ArgAla: 3.067 ± 0.035	1.06ArgCys: 1.06 ± 0.024	2.623ArgAsp: 2.623 ± 0.034	3.724ArgGlu: 3.724 ± 0.051	1.926ArgPhe: 1.926 ± 0.029	2.8ArgGly: 2.8 ± 0.039	1.425ArgHis: 1.425 ± 0.025	2.565ArgIle: 2.565 ± 0.031	4.072ArgLys: 4.072 ± 0.049	4.755ArgLeu: 4.755 ± 0.045	1.175ArgMet: 1.175 ± 0.019	2.236ArgAsn: 2.236 ± 0.03	2.368ArgPro: 2.368 ± 0.036	2.495ArgGln: 2.495 ± 0.036	3.625ArgArg: 3.625 ± 0.047	3.838ArgSer: 3.838 ± 0.052	2.663ArgThr: 2.663 ± 0.031	2.925ArgVal: 2.925 ± 0.034	0.627ArgTrp: 0.627 ± 0.015	1.586ArgTyr: 1.586 ± 0.024	0.001ArgXaa: 0.001 ± 0.001
Ser	5.053SerAla: 5.053 ± 0.054	1.862SerCys: 1.862 ± 0.033	4.05SerAsp: 4.05 ± 0.05	5.156SerGlu: 5.156 ± 0.059	3.227SerPhe: 3.227 ± 0.033	4.854SerGly: 4.854 ± 0.045	2.039SerHis: 2.039 ± 0.029	3.68SerIle: 3.68 ± 0.041	4.605SerLys: 4.605 ± 0.05	8.048SerLeu: 8.048 ± 0.068	1.68SerMet: 1.68 ± 0.027	3.165SerAsn: 3.165 ± 0.04	5.076SerPro: 5.076 ± 0.058	3.724SerGln: 3.724 ± 0.044	3.972SerArg: 3.972 ± 0.049	9.257SerSer: 9.257 ± 0.12	4.622SerThr: 4.622 ± 0.045	5.094SerVal: 5.094 ± 0.05	0.964SerTrp: 0.964 ± 0.019	2.282SerTyr: 2.282 ± 0.031	0.002SerXaa: 0.002 ± 0.001
Thr	3.816ThrAla: 3.816 ± 0.038	1.305ThrCys: 1.305 ± 0.031	2.723ThrAsp: 2.723 ± 0.031	3.788ThrGlu: 3.788 ± 0.041	2.228ThrPhe: 2.228 ± 0.033	3.398ThrGly: 3.398 ± 0.037	1.231ThrHis: 1.231 ± 0.027	2.668ThrIle: 2.668 ± 0.034	2.976ThrLys: 2.976 ± 0.034	5.17ThrLeu: 5.17 ± 0.053	1.123ThrMet: 1.123 ± 0.02	1.996ThrAsn: 1.996 ± 0.026	3.11ThrPro: 3.11 ± 0.044	2.145ThrGln: 2.145 ± 0.03	2.31ThrArg: 2.31 ± 0.031	4.719ThrSer: 4.719 ± 0.056	3.005ThrThr: 3.005 ± 0.045	4.173ThrVal: 4.173 ± 0.05	0.669ThrTrp: 0.669 ± 0.017	1.56ThrTyr: 1.56 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	4.099ValAla: 4.099 ± 0.043	1.54ValCys: 1.54 ± 0.031	3.064ValAsp: 3.064 ± 0.036	4.023ValGlu: 4.023 ± 0.047	2.703ValPhe: 2.703 ± 0.038	3.302ValGly: 3.302 ± 0.045	1.58ValHis: 1.58 ± 0.023	3.399ValIle: 3.399 ± 0.037	3.881ValLys: 3.881 ± 0.041	6.301ValLeu: 6.301 ± 0.054	1.423ValMet: 1.423 ± 0.024	2.591ValAsn: 2.591 ± 0.036	3.39ValPro: 3.39 ± 0.042	2.84ValGln: 2.84 ± 0.032	2.891ValArg: 2.891 ± 0.033	5.027ValSer: 5.027 ± 0.047	3.925ValThr: 3.925 ± 0.042	4.23ValVal: 4.23 ± 0.044	0.743ValTrp: 0.743 ± 0.019	1.877ValTyr: 1.877 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	0.688TrpAla: 0.688 ± 0.018	0.24TrpCys: 0.24 ± 0.01	0.657TrpAsp: 0.657 ± 0.017	0.767TrpGlu: 0.767 ± 0.019	0.471TrpPhe: 0.471 ± 0.012	0.637TrpGly: 0.637 ± 0.019	0.315TrpHis: 0.315 ± 0.01	0.649TrpIle: 0.649 ± 0.014	0.911TrpLys: 0.911 ± 0.02	1.215TrpLeu: 1.215 ± 0.023	0.336TrpMet: 0.336 ± 0.012	0.607TrpAsn: 0.607 ± 0.018	0.449TrpPro: 0.449 ± 0.013	0.555TrpGln: 0.555 ± 0.013	0.664TrpArg: 0.664 ± 0.018	0.86TrpSer: 0.86 ± 0.019	0.64TrpThr: 0.64 ± 0.015	0.687TrpVal: 0.687 ± 0.015	0.195TrpTrp: 0.195 ± 0.008	0.385TrpTyr: 0.385 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.574TyrAla: 1.574 ± 0.027	0.781TyrCys: 0.781 ± 0.018	1.483TyrAsp: 1.483 ± 0.025	1.852TyrGlu: 1.852 ± 0.027	1.46TyrPhe: 1.46 ± 0.024	1.766TyrGly: 1.766 ± 0.028	0.821TyrHis: 0.821 ± 0.017	1.661TyrIle: 1.661 ± 0.028	1.771TyrLys: 1.771 ± 0.028	2.989TyrLeu: 2.989 ± 0.039	0.709TyrMet: 0.709 ± 0.017	1.314TyrAsn: 1.314 ± 0.024	1.36TyrPro: 1.36 ± 0.025	1.364TyrGln: 1.364 ± 0.026	1.689TyrArg: 1.689 ± 0.03	2.425TyrSer: 2.425 ± 0.032	1.656TyrThr: 1.656 ± 0.032	1.757TyrVal: 1.757 ± 0.028	0.405TyrTrp: 0.405 ± 0.012	1.115TyrTyr: 1.115 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.069XaaXaa: 0.069 ± 0.023

Statistics based on 7080 proteins (2899743 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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