Amino acid dipepetide frequency for Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.629AlaAla: 4.629 ± 0.064	0.769AlaCys: 0.769 ± 0.019	3.128AlaAsp: 3.128 ± 0.039	3.687AlaGlu: 3.687 ± 0.045	2.501AlaPhe: 2.501 ± 0.034	3.442AlaGly: 3.442 ± 0.046	1.25AlaHis: 1.25 ± 0.026	3.754AlaIle: 3.754 ± 0.048	4.341AlaLys: 4.341 ± 0.048	6.06AlaLeu: 6.06 ± 0.065	1.416AlaMet: 1.416 ± 0.026	3.013AlaAsn: 3.013 ± 0.032	2.565AlaPro: 2.565 ± 0.045	2.617AlaGln: 2.617 ± 0.038	2.968AlaArg: 2.968 ± 0.037	5.184AlaSer: 5.184 ± 0.058	3.705AlaThr: 3.705 ± 0.047	3.828AlaVal: 3.828 ± 0.042	0.568AlaTrp: 0.568 ± 0.015	1.817AlaTyr: 1.817 ± 0.029	0.001AlaXaa: 0.001 ± 0.001
Cys	0.707CysAla: 0.707 ± 0.019	0.296CysCys: 0.296 ± 0.012	0.728CysAsp: 0.728 ± 0.019	0.679CysGlu: 0.679 ± 0.019	0.666CysPhe: 0.666 ± 0.018	0.914CysGly: 0.914 ± 0.022	0.336CysHis: 0.336 ± 0.013	0.871CysIle: 0.871 ± 0.018	0.761CysLys: 0.761 ± 0.02	1.323CysLeu: 1.323 ± 0.025	0.279CysMet: 0.279 ± 0.011	0.593CysAsn: 0.593 ± 0.016	0.534CysPro: 0.534 ± 0.015	0.503CysGln: 0.503 ± 0.016	0.584CysArg: 0.584 ± 0.014	1.07CysSer: 1.07 ± 0.02	0.611CysThr: 0.611 ± 0.018	0.847CysVal: 0.847 ± 0.02	0.162CysTrp: 0.162 ± 0.008	0.502CysTyr: 0.502 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.314AspAla: 3.314 ± 0.042	0.723AspCys: 0.723 ± 0.018	4.723AspAsp: 4.723 ± 0.067	5.503AspGlu: 5.503 ± 0.064	2.741AspPhe: 2.741 ± 0.035	3.142AspGly: 3.142 ± 0.044	1.209AspHis: 1.209 ± 0.023	3.62AspIle: 3.62 ± 0.045	3.473AspLys: 3.473 ± 0.039	5.888AspLeu: 5.888 ± 0.051	1.181AspMet: 1.181 ± 0.023	2.649AspAsn: 2.649 ± 0.036	2.575AspPro: 2.575 ± 0.037	2.188AspGln: 2.188 ± 0.031	2.473AspArg: 2.473 ± 0.033	4.863AspSer: 4.863 ± 0.053	2.843AspThr: 2.843 ± 0.032	3.803AspVal: 3.803 ± 0.041	0.663AspTrp: 0.663 ± 0.016	2.153AspTyr: 2.153 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	4.102GluAla: 4.102 ± 0.05	0.677GluCys: 0.677 ± 0.018	4.623GluAsp: 4.623 ± 0.053	6.468GluGlu: 6.468 ± 0.081	2.752GluPhe: 2.752 ± 0.034	3.082GluGly: 3.082 ± 0.038	1.319GluHis: 1.319 ± 0.024	4.096GluIle: 4.096 ± 0.046	5.072GluLys: 5.072 ± 0.06	6.753GluLeu: 6.753 ± 0.068	1.516GluMet: 1.516 ± 0.027	3.662GluAsn: 3.662 ± 0.042	2.388GluPro: 2.388 ± 0.041	2.935GluGln: 2.935 ± 0.034	3.378GluArg: 3.378 ± 0.04	5.248GluSer: 5.248 ± 0.057	3.692GluThr: 3.692 ± 0.043	3.936GluVal: 3.936 ± 0.047	0.701GluTrp: 0.701 ± 0.019	2.187GluTyr: 2.187 ± 0.026	0.001GluXaa: 0.001 ± 0.001
Phe	2.639PheAla: 2.639 ± 0.035	0.571PheCys: 0.571 ± 0.016	2.751PheAsp: 2.751 ± 0.034	2.87PheGlu: 2.87 ± 0.036	1.979PhePhe: 1.979 ± 0.035	2.631PheGly: 2.631 ± 0.05	1.015PheHis: 1.015 ± 0.02	2.573PheIle: 2.573 ± 0.037	2.85PheLys: 2.85 ± 0.036	4.051PheLeu: 4.051 ± 0.047	0.94PheMet: 0.94 ± 0.021	2.269PheAsn: 2.269 ± 0.034	1.768PhePro: 1.768 ± 0.03	1.84PheGln: 1.84 ± 0.025	1.71PheArg: 1.71 ± 0.025	3.389PheSer: 3.389 ± 0.041	2.448PheThr: 2.448 ± 0.035	2.648PheVal: 2.648 ± 0.033	0.503PheTrp: 0.503 ± 0.016	1.55PheTyr: 1.55 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	3.259GlyAla: 3.259 ± 0.046	0.789GlyCys: 0.789 ± 0.018	2.968GlyAsp: 2.968 ± 0.039	3.238GlyGlu: 3.238 ± 0.043	2.512GlyPhe: 2.512 ± 0.033	3.514GlyGly: 3.514 ± 0.057	1.213GlyHis: 1.213 ± 0.025	3.339GlyIle: 3.339 ± 0.039	3.787GlyLys: 3.787 ± 0.042	5.009GlyLeu: 5.009 ± 0.055	1.06GlyMet: 1.06 ± 0.021	2.695GlyAsn: 2.695 ± 0.039	1.873GlyPro: 1.873 ± 0.026	1.967GlyGln: 1.967 ± 0.038	2.47GlyArg: 2.47 ± 0.039	5.183GlySer: 5.183 ± 0.06	3.079GlyThr: 3.079 ± 0.043	3.393GlyVal: 3.393 ± 0.044	0.632GlyTrp: 0.632 ± 0.016	1.887GlyTyr: 1.887 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	1.115HisAla: 1.115 ± 0.022	0.331HisCys: 0.331 ± 0.012	1.229HisAsp: 1.229 ± 0.025	1.37HisGlu: 1.37 ± 0.025	0.982HisPhe: 0.982 ± 0.02	1.276HisGly: 1.276 ± 0.023	0.656HisHis: 0.656 ± 0.021	1.27HisIle: 1.27 ± 0.022	1.266HisLys: 1.266 ± 0.024	2.194HisLeu: 2.194 ± 0.031	0.454HisMet: 0.454 ± 0.013	1.003HisAsn: 1.003 ± 0.02	1.076HisPro: 1.076 ± 0.024	0.918HisGln: 0.918 ± 0.02	1.168HisArg: 1.168 ± 0.018	1.815HisSer: 1.815 ± 0.028	1.036HisThr: 1.036 ± 0.021	1.225HisVal: 1.225 ± 0.022	0.264HisTrp: 0.264 ± 0.01	0.832HisTyr: 0.832 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	3.775IleAla: 3.775 ± 0.042	0.878IleCys: 0.878 ± 0.022	3.856IleAsp: 3.856 ± 0.048	3.815IleGlu: 3.815 ± 0.048	2.547IlePhe: 2.547 ± 0.035	3.056IleGly: 3.056 ± 0.038	1.228IleHis: 1.228 ± 0.026	3.391IleIle: 3.391 ± 0.043	3.877IleLys: 3.877 ± 0.046	5.537IleLeu: 5.537 ± 0.056	1.222IleMet: 1.222 ± 0.023	2.939IleAsn: 2.939 ± 0.036	3.024IlePro: 3.024 ± 0.035	2.193IleGln: 2.193 ± 0.03	2.744IleArg: 2.744 ± 0.035	5.048IleSer: 5.048 ± 0.048	3.307IleThr: 3.307 ± 0.04	3.712IleVal: 3.712 ± 0.043	0.66IleTrp: 0.66 ± 0.016	1.931IleTyr: 1.931 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.84LysAla: 3.84 ± 0.04	0.808LysCys: 0.808 ± 0.02	4.038LysAsp: 4.038 ± 0.048	4.938LysGlu: 4.938 ± 0.057	2.898LysPhe: 2.898 ± 0.036	3.033LysGly: 3.033 ± 0.04	1.408LysHis: 1.408 ± 0.026	4.106LysIle: 4.106 ± 0.05	5.839LysLys: 5.839 ± 0.077	6.912LysLeu: 6.912 ± 0.068	1.51LysMet: 1.51 ± 0.026	3.671LysAsn: 3.671 ± 0.04	2.876LysPro: 2.876 ± 0.046	2.775LysGln: 2.775 ± 0.037	4.04LysArg: 4.04 ± 0.049	5.252LysSer: 5.252 ± 0.049	3.601LysThr: 3.601 ± 0.035	4.208LysVal: 4.208 ± 0.046	0.767LysTrp: 0.767 ± 0.017	2.369LysTyr: 2.369 ± 0.03	0.002LysXaa: 0.002 ± 0.001
Leu	6.085LeuAla: 6.085 ± 0.052	1.368LeuCys: 1.368 ± 0.028	5.498LeuAsp: 5.498 ± 0.056	6.483LeuGlu: 6.483 ± 0.065	4.002LeuPhe: 4.002 ± 0.056	4.818LeuGly: 4.818 ± 0.055	2.122LeuHis: 2.122 ± 0.032	5.45LeuIle: 5.45 ± 0.062	7.309LeuLys: 7.309 ± 0.06	9.806LeuLeu: 9.806 ± 0.102	2.069LeuMet: 2.069 ± 0.027	5.049LeuAsn: 5.049 ± 0.049	4.685LeuPro: 4.685 ± 0.052	4.638LeuGln: 4.638 ± 0.056	5.081LeuArg: 5.081 ± 0.05	8.099LeuSer: 8.099 ± 0.065	5.284LeuThr: 5.284 ± 0.053	5.571LeuVal: 5.571 ± 0.052	0.981LeuTrp: 0.981 ± 0.019	3.081LeuTyr: 3.081 ± 0.042	0.002LeuXaa: 0.002 ± 0.001
Met	1.542MetAla: 1.542 ± 0.025	0.276MetCys: 0.276 ± 0.011	1.283MetAsp: 1.283 ± 0.024	1.318MetGlu: 1.318 ± 0.025	0.853MetPhe: 0.853 ± 0.02	1.265MetGly: 1.265 ± 0.025	0.362MetHis: 0.362 ± 0.012	1.306MetIle: 1.306 ± 0.021	1.453MetLys: 1.453 ± 0.026	1.906MetLeu: 1.906 ± 0.032	0.553MetMet: 0.553 ± 0.015	1.186MetAsn: 1.186 ± 0.022	0.852MetPro: 0.852 ± 0.02	0.744MetGln: 0.744 ± 0.019	1.003MetArg: 1.003 ± 0.018	2.112MetSer: 2.112 ± 0.029	1.215MetThr: 1.215 ± 0.021	1.305MetVal: 1.305 ± 0.023	0.194MetTrp: 0.194 ± 0.009	0.569MetTyr: 0.569 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.138AsnAla: 3.138 ± 0.037	0.64AsnCys: 0.64 ± 0.017	3.284AsnAsp: 3.284 ± 0.044	3.619AsnGlu: 3.619 ± 0.045	2.184AsnPhe: 2.184 ± 0.029	3.29AsnGly: 3.29 ± 0.039	1.092AsnHis: 1.092 ± 0.023	2.849AsnIle: 2.849 ± 0.033	3.218AsnLys: 3.218 ± 0.044	4.691AsnLeu: 4.691 ± 0.042	1.073AsnMet: 1.073 ± 0.021	2.751AsnAsn: 2.751 ± 0.041	2.229AsnPro: 2.229 ± 0.034	1.812AsnGln: 1.812 ± 0.031	2.17AsnArg: 2.17 ± 0.034	4.386AsnSer: 4.386 ± 0.05	2.603AsnThr: 2.603 ± 0.039	3.255AsnVal: 3.255 ± 0.039	0.601AsnTrp: 0.601 ± 0.016	1.771AsnTyr: 1.771 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	2.675ProAla: 2.675 ± 0.041	0.394ProCys: 0.394 ± 0.014	2.233ProAsp: 2.233 ± 0.029	3.158ProGlu: 3.158 ± 0.043	1.891ProPhe: 1.891 ± 0.033	2.132ProGly: 2.132 ± 0.033	0.944ProHis: 0.944 ± 0.021	2.546ProIle: 2.546 ± 0.033	2.791ProLys: 2.791 ± 0.04	4.172ProLeu: 4.172 ± 0.039	0.878ProMet: 0.878 ± 0.021	2.14ProAsn: 2.14 ± 0.032	2.405ProPro: 2.405 ± 0.064	2.111ProGln: 2.111 ± 0.031	1.983ProArg: 1.983 ± 0.034	4.162ProSer: 4.162 ± 0.055	2.702ProThr: 2.702 ± 0.043	2.941ProVal: 2.941 ± 0.038	0.463ProTrp: 0.463 ± 0.014	1.355ProTyr: 1.355 ± 0.024	0.001ProXaa: 0.001 ± 0.001
Gln	2.441GlnAla: 2.441 ± 0.038	0.479GlnCys: 0.479 ± 0.015	2.38GlnAsp: 2.38 ± 0.027	3.115GlnGlu: 3.115 ± 0.042	1.768GlnPhe: 1.768 ± 0.029	1.949GlnGly: 1.949 ± 0.031	0.902GlnHis: 0.902 ± 0.021	2.331GlnIle: 2.331 ± 0.031	2.595GlnLys: 2.595 ± 0.04	4.404GlnLeu: 4.404 ± 0.044	0.909GlnMet: 0.909 ± 0.022	2.069GlnAsn: 2.069 ± 0.035	1.802GlnPro: 1.802 ± 0.033	2.838GlnGln: 2.838 ± 0.092	2.332GlnArg: 2.332 ± 0.035	3.121GlnSer: 3.121 ± 0.041	2.063GlnThr: 2.063 ± 0.028	2.437GlnVal: 2.437 ± 0.032	0.489GlnTrp: 0.489 ± 0.015	1.392GlnTyr: 1.392 ± 0.024	0.001GlnXaa: 0.001 ± 0.001
Arg	2.806ArgAla: 2.806 ± 0.037	0.682ArgCys: 0.682 ± 0.016	2.849ArgAsp: 2.849 ± 0.034	3.232ArgGlu: 3.232 ± 0.037	2.097ArgPhe: 2.097 ± 0.031	2.417ArgGly: 2.417 ± 0.038	1.112ArgHis: 1.112 ± 0.018	2.926ArgIle: 2.926 ± 0.039	3.793ArgLys: 3.793 ± 0.049	4.851ArgLeu: 4.851 ± 0.048	1.014ArgMet: 1.014 ± 0.023	2.553ArgAsn: 2.553 ± 0.034	1.958ArgPro: 1.958 ± 0.027	2.063ArgGln: 2.063 ± 0.033	3.355ArgArg: 3.355 ± 0.044	4.103ArgSer: 4.103 ± 0.05	2.525ArgThr: 2.525 ± 0.033	2.737ArgVal: 2.737 ± 0.035	0.551ArgTrp: 0.551 ± 0.015	1.674ArgTyr: 1.674 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	4.964SerAla: 4.964 ± 0.055	1.018SerCys: 1.018 ± 0.025	4.635SerAsp: 4.635 ± 0.054	4.943SerGlu: 4.943 ± 0.047	3.631SerPhe: 3.631 ± 0.042	4.811SerGly: 4.811 ± 0.055	1.907SerHis: 1.907 ± 0.027	4.944SerIle: 4.944 ± 0.05	5.872SerLys: 5.872 ± 0.05	8.356SerLeu: 8.356 ± 0.071	1.904SerMet: 1.904 ± 0.031	4.474SerAsn: 4.474 ± 0.05	3.826SerPro: 3.826 ± 0.051	3.603SerGln: 3.603 ± 0.041	4.218SerArg: 4.218 ± 0.045	9.733SerSer: 9.733 ± 0.159	5.422SerThr: 5.422 ± 0.081	4.88SerVal: 4.88 ± 0.053	0.864SerTrp: 0.864 ± 0.018	2.466SerTyr: 2.466 ± 0.037	0.001SerXaa: 0.001 ± 0.001
Thr	3.611ThrAla: 3.611 ± 0.044	0.678ThrCys: 0.678 ± 0.018	2.896ThrAsp: 2.896 ± 0.031	3.22ThrGlu: 3.22 ± 0.042	2.356ThrPhe: 2.356 ± 0.032	3.284ThrGly: 3.284 ± 0.047	1.128ThrHis: 1.128 ± 0.024	3.305ThrIle: 3.305 ± 0.037	3.622ThrLys: 3.622 ± 0.037	5.366ThrLeu: 5.366 ± 0.05	1.156ThrMet: 1.156 ± 0.025	2.75ThrAsn: 2.75 ± 0.039	2.908ThrPro: 2.908 ± 0.041	1.972ThrGln: 1.972 ± 0.033	2.543ThrArg: 2.543 ± 0.031	5.113ThrSer: 5.113 ± 0.079	3.731ThrThr: 3.731 ± 0.08	3.663ThrVal: 3.663 ± 0.049	0.588ThrTrp: 0.588 ± 0.014	1.62ThrTyr: 1.62 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	4.081ValAla: 4.081 ± 0.047	0.822ValCys: 0.822 ± 0.018	3.768ValAsp: 3.768 ± 0.044	4.213ValGlu: 4.213 ± 0.04	2.6ValPhe: 2.6 ± 0.035	3.269ValGly: 3.269 ± 0.042	1.209ValHis: 1.209 ± 0.025	3.602ValIle: 3.602 ± 0.036	4.084ValLys: 4.084 ± 0.047	5.879ValLeu: 5.879 ± 0.053	1.214ValMet: 1.214 ± 0.021	2.875ValAsn: 2.875 ± 0.034	3.078ValPro: 3.078 ± 0.038	2.229ValGln: 2.229 ± 0.029	2.89ValArg: 2.89 ± 0.035	5.143ValSer: 5.143 ± 0.056	3.456ValThr: 3.456 ± 0.039	4.211ValVal: 4.211 ± 0.051	0.635ValTrp: 0.635 ± 0.017	1.941ValTyr: 1.941 ± 0.029	0.002ValXaa: 0.002 ± 0.001
Trp	0.586TrpAla: 0.586 ± 0.016	0.244TrpCys: 0.244 ± 0.009	0.728TrpAsp: 0.728 ± 0.017	0.648TrpGlu: 0.648 ± 0.018	0.529TrpPhe: 0.529 ± 0.015	0.584TrpGly: 0.584 ± 0.016	0.24TrpHis: 0.24 ± 0.011	0.619TrpIle: 0.619 ± 0.019	0.826TrpLys: 0.826 ± 0.021	1.055TrpLeu: 1.055 ± 0.024	0.225TrpMet: 0.225 ± 0.01	0.634TrpAsn: 0.634 ± 0.017	0.327TrpPro: 0.327 ± 0.013	0.431TrpGln: 0.431 ± 0.015	0.584TrpArg: 0.584 ± 0.019	0.898TrpSer: 0.898 ± 0.018	0.551TrpThr: 0.551 ± 0.017	0.574TrpVal: 0.574 ± 0.013	0.16TrpTrp: 0.16 ± 0.008	0.397TrpTyr: 0.397 ± 0.013	0.001TrpXaa: 0.001 ± 0.001
Tyr	1.932TyrAla: 1.932 ± 0.032	0.525TyrCys: 0.525 ± 0.017	2.131TyrAsp: 2.131 ± 0.029	2.07TyrGlu: 2.07 ± 0.032	1.507TyrPhe: 1.507 ± 0.028	1.957TyrGly: 1.957 ± 0.037	0.825TyrHis: 0.825 ± 0.02	1.841TyrIle: 1.841 ± 0.027	2.063TyrLys: 2.063 ± 0.029	3.267TyrLeu: 3.267 ± 0.041	0.721TyrMet: 0.721 ± 0.019	1.678TyrAsn: 1.678 ± 0.028	1.327TyrPro: 1.327 ± 0.024	1.44TyrGln: 1.44 ± 0.026	1.602TyrArg: 1.602 ± 0.026	2.547TyrSer: 2.547 ± 0.034	1.633TyrThr: 1.633 ± 0.026	2.031TyrVal: 2.031 ± 0.033	0.395TyrTrp: 0.395 ± 0.015	1.326TyrTyr: 1.326 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.024XaaXaa: 0.024 ± 0.012

Statistics based on 4966 proteins (2412323 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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