Amino acid dipepetide frequency for Torque teno virus 24

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.54AlaAla: 16.54 ± 9.832
2.068AlaCys: 2.068 ± 1.547
0.689AlaAsp: 0.689 ± 0.405
1.378AlaGlu: 1.378 ± 0.81
1.378AlaPhe: 1.378 ± 0.81
8.959AlaGly: 8.959 ± 3.797
0.689AlaHis: 0.689 ± 0.694
1.378AlaIle: 1.378 ± 0.81
0.689AlaLys: 0.689 ± 0.694
6.892AlaLeu: 6.892 ± 2.987
0.0AlaMet: 0.0 ± 0.0
2.068AlaAsn: 2.068 ± 1.215
4.824AlaPro: 4.824 ± 1.466
2.068AlaGln: 2.068 ± 0.721
6.203AlaArg: 6.203 ± 1.66
4.135AlaSer: 4.135 ± 1.201
4.824AlaThr: 4.824 ± 2.272
2.757AlaVal: 2.757 ± 1.169
1.378AlaTrp: 1.378 ± 0.628
3.446AlaTyr: 3.446 ± 0.816
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.757CysAsp: 2.757 ± 1.169
0.0CysGlu: 0.0 ± 0.0
0.689CysPhe: 0.689 ± 0.405
5.513CysGly: 5.513 ± 2.337
1.378CysHis: 1.378 ± 0.652
1.378CysIle: 1.378 ± 0.81
2.068CysLys: 2.068 ± 0.796
0.0CysLeu: 0.0 ± 0.0
0.689CysMet: 0.689 ± 0.405
0.0CysAsn: 0.0 ± 0.0
1.378CysPro: 1.378 ± 0.81
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.689CysSer: 0.689 ± 0.405
0.689CysThr: 0.689 ± 0.405
0.689CysVal: 0.689 ± 0.405
0.689CysTrp: 0.689 ± 0.405
0.689CysTyr: 0.689 ± 0.405
0.0CysXaa: 0.0 ± 0.0
Asp
7.581AspAla: 7.581 ± 3.88
0.0AspCys: 0.0 ± 0.0
0.689AspAsp: 0.689 ± 0.405
6.203AspGlu: 6.203 ± 2.654
4.824AspPhe: 4.824 ± 0.499
5.513AspGly: 5.513 ± 3.157
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
1.378AspLys: 1.378 ± 0.652
8.27AspLeu: 8.27 ± 1.083
0.689AspMet: 0.689 ± 0.812
1.378AspAsn: 1.378 ± 0.652
1.378AspPro: 1.378 ± 0.652
2.757AspGln: 2.757 ± 1.169
2.757AspArg: 2.757 ± 1.096
2.068AspSer: 2.068 ± 1.416
2.068AspThr: 2.068 ± 0.569
0.689AspVal: 0.689 ± 0.405
0.689AspTrp: 0.689 ± 0.405
1.378AspTyr: 1.378 ± 0.81
0.0AspXaa: 0.0 ± 0.0
Glu
1.378GluAla: 1.378 ± 0.628
0.689GluCys: 0.689 ± 0.812
6.203GluAsp: 6.203 ± 0.744
4.135GluGlu: 4.135 ± 0.541
0.0GluPhe: 0.0 ± 0.0
0.689GluGly: 0.689 ± 0.812
0.689GluHis: 0.689 ± 0.405
0.689GluIle: 0.689 ± 0.405
1.378GluLys: 1.378 ± 0.652
2.068GluLeu: 2.068 ± 1.215
0.689GluMet: 0.689 ± 0.812
4.135GluAsn: 4.135 ± 0.541
3.446GluPro: 3.446 ± 2.433
6.203GluGln: 6.203 ± 1.069
2.068GluArg: 2.068 ± 1.547
1.378GluSer: 1.378 ± 0.652
3.446GluThr: 3.446 ± 0.816
2.757GluVal: 2.757 ± 1.169
0.689GluTrp: 0.689 ± 0.405
1.378GluTyr: 1.378 ± 0.628
0.0GluXaa: 0.0 ± 0.0
Phe
6.892PheAla: 6.892 ± 1.632
2.757PheCys: 2.757 ± 1.169
0.0PheAsp: 0.0 ± 0.0
2.068PheGlu: 2.068 ± 0.796
0.689PhePhe: 0.689 ± 0.405
2.757PheGly: 2.757 ± 1.62
2.068PheHis: 2.068 ± 1.215
4.824PheIle: 4.824 ± 0.499
4.135PheLys: 4.135 ± 1.883
1.378PheLeu: 1.378 ± 0.652
1.378PheMet: 1.378 ± 0.81
0.0PheAsn: 0.0 ± 0.0
2.068PhePro: 2.068 ± 0.721
2.757PheGln: 2.757 ± 1.62
2.757PheArg: 2.757 ± 1.169
1.378PheSer: 1.378 ± 0.81
1.378PheThr: 1.378 ± 0.628
0.0PheVal: 0.0 ± 0.0
0.689PheTrp: 0.689 ± 0.405
2.068PheTyr: 2.068 ± 1.215
0.0PheXaa: 0.0 ± 0.0
Gly
4.135GlyAla: 4.135 ± 2.663
2.068GlyCys: 2.068 ± 1.547
11.716GlyAsp: 11.716 ± 7.758
0.689GlyGlu: 0.689 ± 0.694
2.068GlyPhe: 2.068 ± 0.569
13.094GlyGly: 13.094 ± 6.985
2.068GlyHis: 2.068 ± 1.215
2.068GlyIle: 2.068 ± 1.215
2.068GlyLys: 2.068 ± 0.796
2.757GlyLeu: 2.757 ± 1.096
2.068GlyMet: 2.068 ± 1.215
4.824GlyAsn: 4.824 ± 0.499
6.203GlyPro: 6.203 ± 1.975
0.0GlyGln: 0.0 ± 0.0
6.203GlyArg: 6.203 ± 1.327
5.513GlySer: 5.513 ± 2.043
2.068GlyThr: 2.068 ± 0.721
1.378GlyVal: 1.378 ± 0.81
0.0GlyTrp: 0.0 ± 0.0
1.378GlyTyr: 1.378 ± 0.81
0.0GlyXaa: 0.0 ± 0.0
His
2.068HisAla: 2.068 ± 1.547
0.0HisCys: 0.0 ± 0.0
0.689HisAsp: 0.689 ± 0.405
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.068HisGly: 2.068 ± 0.721
0.0HisHis: 0.0 ± 0.0
0.689HisIle: 0.689 ± 0.405
1.378HisLys: 1.378 ± 0.81
3.446HisLeu: 3.446 ± 1.548
0.0HisMet: 0.0 ± 0.0
0.689HisAsn: 0.689 ± 0.405
2.068HisPro: 2.068 ± 0.796
2.068HisGln: 2.068 ± 0.721
2.068HisArg: 2.068 ± 0.569
0.689HisSer: 0.689 ± 0.405
2.757HisThr: 2.757 ± 1.62
0.689HisVal: 0.689 ± 0.694
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.689IleAla: 0.689 ± 0.405
1.378IleCys: 1.378 ± 0.81
0.689IleAsp: 0.689 ± 0.812
0.689IleGlu: 0.689 ± 0.405
0.689IlePhe: 0.689 ± 0.405
1.378IleGly: 1.378 ± 0.81
2.068IleHis: 2.068 ± 0.796
2.068IleIle: 2.068 ± 0.796
1.378IleLys: 1.378 ± 0.81
2.757IleLeu: 2.757 ± 1.169
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.068IlePro: 2.068 ± 1.215
0.689IleGln: 0.689 ± 0.405
2.757IleArg: 2.757 ± 1.096
1.378IleSer: 1.378 ± 0.81
2.068IleThr: 2.068 ± 1.215
2.068IleVal: 2.068 ± 0.796
2.757IleTrp: 2.757 ± 1.169
2.068IleTyr: 2.068 ± 1.215
0.0IleXaa: 0.0 ± 0.0
Lys
2.068LysAla: 2.068 ± 0.569
0.689LysCys: 0.689 ± 0.405
1.378LysAsp: 1.378 ± 0.81
0.689LysGlu: 0.689 ± 0.812
1.378LysPhe: 1.378 ± 0.81
0.0LysGly: 0.0 ± 0.0
0.0LysHis: 0.0 ± 0.0
0.689LysIle: 0.689 ± 0.405
6.892LysLys: 6.892 ± 3.014
4.135LysLeu: 4.135 ± 0.914
1.378LysMet: 1.378 ± 0.81
1.378LysAsn: 1.378 ± 0.81
6.203LysPro: 6.203 ± 1.555
0.689LysGln: 0.689 ± 0.405
4.135LysArg: 4.135 ± 0.888
0.689LysSer: 0.689 ± 0.812
4.135LysThr: 4.135 ± 1.442
2.068LysVal: 2.068 ± 1.26
2.068LysTrp: 2.068 ± 1.215
3.446LysTyr: 3.446 ± 1.448
0.0LysXaa: 0.0 ± 0.0
Leu
5.513LeuAla: 5.513 ± 0.729
0.689LeuCys: 0.689 ± 0.405
2.068LeuAsp: 2.068 ± 0.796
4.135LeuGlu: 4.135 ± 0.541
3.446LeuPhe: 3.446 ± 1.548
5.513LeuGly: 5.513 ± 0.723
2.757LeuHis: 2.757 ± 1.169
0.0LeuIle: 0.0 ± 0.0
2.757LeuLys: 2.757 ± 1.62
5.513LeuLeu: 5.513 ± 1.062
0.689LeuMet: 0.689 ± 0.405
1.378LeuAsn: 1.378 ± 0.81
4.135LeuPro: 4.135 ± 2.663
10.338LeuGln: 10.338 ± 0.907
4.824LeuArg: 4.824 ± 0.905
6.892LeuSer: 6.892 ± 2.141
5.513LeuThr: 5.513 ± 0.701
4.135LeuVal: 4.135 ± 1.664
0.689LeuTrp: 0.689 ± 0.405
1.378LeuTyr: 1.378 ± 0.652
0.0LeuXaa: 0.0 ± 0.0
Met
0.689MetAla: 0.689 ± 0.405
1.378MetCys: 1.378 ± 0.81
0.0MetAsp: 0.0 ± 0.0
0.689MetGlu: 0.689 ± 0.405
1.378MetPhe: 1.378 ± 0.652
0.689MetGly: 0.689 ± 0.405
1.378MetHis: 1.378 ± 0.81
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.378MetLeu: 1.378 ± 1.623
1.378MetMet: 1.378 ± 0.81
0.689MetAsn: 0.689 ± 0.405
1.378MetPro: 1.378 ± 0.628
1.378MetGln: 1.378 ± 0.81
0.0MetArg: 0.0 ± 0.0
2.068MetSer: 2.068 ± 1.547
0.689MetThr: 0.689 ± 0.405
2.068MetVal: 2.068 ± 1.215
0.0MetTrp: 0.0 ± 0.0
0.689MetTyr: 0.689 ± 0.405
0.0MetXaa: 0.0 ± 0.0
Asn
2.068AsnAla: 2.068 ± 0.796
1.378AsnCys: 1.378 ± 0.81
0.689AsnAsp: 0.689 ± 0.405
0.0AsnGlu: 0.0 ± 0.0
2.068AsnPhe: 2.068 ± 0.796
1.378AsnGly: 1.378 ± 0.81
0.689AsnHis: 0.689 ± 0.694
1.378AsnIle: 1.378 ± 0.81
3.446AsnLys: 3.446 ± 1.448
4.135AsnLeu: 4.135 ± 0.541
0.689AsnMet: 0.689 ± 0.405
3.446AsnAsn: 3.446 ± 2.025
6.892AsnPro: 6.892 ± 1.443
0.0AsnGln: 0.0 ± 0.0
1.378AsnArg: 1.378 ± 0.652
2.068AsnSer: 2.068 ± 0.721
2.757AsnThr: 2.757 ± 1.62
2.757AsnVal: 2.757 ± 2.056
2.068AsnTrp: 2.068 ± 1.547
0.689AsnTyr: 0.689 ± 0.405
0.0AsnXaa: 0.0 ± 0.0
Pro
5.513ProAla: 5.513 ± 2.427
2.068ProCys: 2.068 ± 1.215
2.757ProAsp: 2.757 ± 0.971
4.135ProGlu: 4.135 ± 0.541
2.757ProPhe: 2.757 ± 1.62
8.27ProGly: 8.27 ± 4.175
0.689ProHis: 0.689 ± 0.405
4.135ProIle: 4.135 ± 1.533
1.378ProLys: 1.378 ± 0.628
8.959ProLeu: 8.959 ± 0.959
2.068ProMet: 2.068 ± 1.031
2.757ProAsn: 2.757 ± 1.62
19.986ProPro: 19.986 ± 9.649
3.446ProGln: 3.446 ± 0.58
11.716ProArg: 11.716 ± 3.337
4.135ProSer: 4.135 ± 1.442
5.513ProThr: 5.513 ± 2.897
2.068ProVal: 2.068 ± 1.215
3.446ProTrp: 3.446 ± 2.275
0.689ProTyr: 0.689 ± 0.405
0.0ProXaa: 0.0 ± 0.0
Gln
3.446GlnAla: 3.446 ± 0.816
0.689GlnCys: 0.689 ± 0.405
0.689GlnAsp: 0.689 ± 0.405
4.135GlnGlu: 4.135 ± 2.43
0.689GlnPhe: 0.689 ± 0.405
2.757GlnGly: 2.757 ± 1.169
0.0GlnHis: 0.0 ± 0.0
1.378GlnIle: 1.378 ± 0.81
3.446GlnLys: 3.446 ± 1.301
4.135GlnLeu: 4.135 ± 1.664
1.378GlnMet: 1.378 ± 1.26
1.378GlnAsn: 1.378 ± 0.628
0.689GlnPro: 0.689 ± 0.812
5.513GlnGln: 5.513 ± 0.723
6.203GlnArg: 6.203 ± 2.993
5.513GlnSer: 5.513 ± 1.701
3.446GlnThr: 3.446 ± 1.314
3.446GlnVal: 3.446 ± 2.025
1.378GlnTrp: 1.378 ± 0.81
0.689GlnTyr: 0.689 ± 0.405
0.0GlnXaa: 0.0 ± 0.0
Arg
7.581ArgAla: 7.581 ± 2.59
0.0ArgCys: 0.0 ± 0.0
2.068ArgAsp: 2.068 ± 0.721
8.27ArgGlu: 8.27 ± 3.084
4.135ArgPhe: 4.135 ± 1.201
6.203ArgGly: 6.203 ± 2.389
0.0ArgHis: 0.0 ± 0.0
1.378ArgIle: 1.378 ± 0.81
3.446ArgLys: 3.446 ± 2.049
3.446ArgLeu: 3.446 ± 1.375
0.0ArgMet: 0.0 ± 0.0
5.513ArgAsn: 5.513 ± 0.701
13.094ArgPro: 13.094 ± 2.912
2.757ArgGln: 2.757 ± 0.971
27.567ArgArg: 27.567 ± 8.964
3.446ArgSer: 3.446 ± 1.449
6.203ArgThr: 6.203 ± 2.292
2.757ArgVal: 2.757 ± 1.304
4.135ArgTrp: 4.135 ± 2.43
2.757ArgTyr: 2.757 ± 1.62
0.0ArgXaa: 0.0 ± 0.0
Ser
3.446SerAla: 3.446 ± 1.301
0.689SerCys: 0.689 ± 0.405
6.203SerAsp: 6.203 ± 4.749
0.689SerGlu: 0.689 ± 0.405
5.513SerPhe: 5.513 ± 0.723
2.757SerGly: 2.757 ± 1.253
2.068SerHis: 2.068 ± 1.547
4.135SerIle: 4.135 ± 0.541
2.068SerLys: 2.068 ± 1.416
4.135SerLeu: 4.135 ± 1.442
0.0SerMet: 0.0 ± 0.0
0.0SerAsn: 0.0 ± 0.0
8.959SerPro: 8.959 ± 2.509
2.068SerGln: 2.068 ± 0.721
3.446SerArg: 3.446 ± 3.019
9.649SerSer: 9.649 ± 8.251
5.513SerThr: 5.513 ± 2.016
0.689SerVal: 0.689 ± 0.405
0.0SerTrp: 0.0 ± 0.0
3.446SerTyr: 3.446 ± 1.301
0.0SerXaa: 0.0 ± 0.0
Thr
1.378ThrAla: 1.378 ± 0.628
1.378ThrCys: 1.378 ± 0.628
3.446ThrAsp: 3.446 ± 1.301
4.135ThrGlu: 4.135 ± 2.357
6.203ThrPhe: 6.203 ± 1.069
2.757ThrGly: 2.757 ± 0.407
2.757ThrHis: 2.757 ± 1.304
1.378ThrIle: 1.378 ± 0.81
2.068ThrLys: 2.068 ± 1.215
1.378ThrLeu: 1.378 ± 0.652
2.068ThrMet: 2.068 ± 0.667
7.581ThrAsn: 7.581 ± 1.792
3.446ThrPro: 3.446 ± 2.232
4.135ThrGln: 4.135 ± 2.43
7.581ThrArg: 7.581 ± 1.496
2.068ThrSer: 2.068 ± 0.721
5.513ThrThr: 5.513 ± 1.678
1.378ThrVal: 1.378 ± 0.81
1.378ThrTrp: 1.378 ± 0.81
2.757ThrTyr: 2.757 ± 0.407
0.0ThrXaa: 0.0 ± 0.0
Val
0.689ValAla: 0.689 ± 0.812
1.378ValCys: 1.378 ± 0.81
2.757ValAsp: 2.757 ± 1.169
0.689ValGlu: 0.689 ± 0.405
1.378ValPhe: 1.378 ± 0.81
0.689ValGly: 0.689 ± 0.694
0.689ValHis: 0.689 ± 0.694
1.378ValIle: 1.378 ± 0.81
0.0ValLys: 0.0 ± 0.0
2.757ValLeu: 2.757 ± 1.62
1.378ValMet: 1.378 ± 0.81
0.689ValAsn: 0.689 ± 0.405
3.446ValPro: 3.446 ± 2.025
2.757ValGln: 2.757 ± 0.971
5.513ValArg: 5.513 ± 0.729
4.824ValSer: 4.824 ± 1.466
2.068ValThr: 2.068 ± 0.721
1.378ValVal: 1.378 ± 0.81
0.0ValTrp: 0.0 ± 0.0
0.689ValTyr: 0.689 ± 0.694
0.0ValXaa: 0.0 ± 0.0
Trp
0.689TrpAla: 0.689 ± 0.812
0.0TrpCys: 0.0 ± 0.0
2.068TrpAsp: 2.068 ± 0.796
1.378TrpGlu: 1.378 ± 0.628
2.068TrpPhe: 2.068 ± 1.215
0.689TrpGly: 0.689 ± 0.405
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.757TrpLeu: 2.757 ± 1.169
0.689TrpMet: 0.689 ± 0.694
0.0TrpAsn: 0.0 ± 0.0
2.757TrpPro: 2.757 ± 1.169
1.378TrpGln: 1.378 ± 0.81
4.824TrpArg: 4.824 ± 0.499
3.446TrpSer: 3.446 ± 2.025
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.068TrpTrp: 2.068 ± 1.215
0.689TrpTyr: 0.689 ± 0.405
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.757TyrAsp: 2.757 ± 1.169
0.0TyrGlu: 0.0 ± 0.0
0.689TyrPhe: 0.689 ± 0.405
0.689TyrGly: 0.689 ± 0.405
1.378TyrHis: 1.378 ± 0.81
0.689TyrIle: 0.689 ± 0.405
4.135TyrLys: 4.135 ± 1.664
2.068TyrLeu: 2.068 ± 0.796
0.0TyrMet: 0.0 ± 0.0
2.068TyrAsn: 2.068 ± 1.215
2.757TyrPro: 2.757 ± 1.096
0.0TyrGln: 0.0 ± 0.0
2.757TyrArg: 2.757 ± 0.971
3.446TyrSer: 3.446 ± 1.301
4.135TyrThr: 4.135 ± 1.822
1.378TyrVal: 1.378 ± 0.81
1.378TyrTrp: 1.378 ± 0.628
0.689TyrTyr: 0.689 ± 0.405
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1452 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski