Amino acid dipepetide frequency for Trabulsiella guamensis ATCC 49490

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.225AlaAla: 10.225 ± 0.123	1.04AlaCys: 1.04 ± 0.029	5.151AlaAsp: 5.151 ± 0.065	5.72AlaGlu: 5.72 ± 0.079	3.598AlaPhe: 3.598 ± 0.057	7.853AlaGly: 7.853 ± 0.113	1.8AlaHis: 1.8 ± 0.037	5.712AlaIle: 5.712 ± 0.072	3.815AlaLys: 3.815 ± 0.068	11.614AlaLeu: 11.614 ± 0.124	2.938AlaMet: 2.938 ± 0.047	3.043AlaAsn: 3.043 ± 0.054	3.634AlaPro: 3.634 ± 0.061	4.39AlaGln: 4.39 ± 0.067	5.581AlaArg: 5.581 ± 0.08	5.723AlaSer: 5.723 ± 0.075	5.214AlaThr: 5.214 ± 0.088	6.721AlaVal: 6.721 ± 0.071	1.613AlaTrp: 1.613 ± 0.044	1.924AlaTyr: 1.924 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.929CysAla: 0.929 ± 0.023	0.157CysCys: 0.157 ± 0.012	0.608CysAsp: 0.608 ± 0.023	0.59CysGlu: 0.59 ± 0.023	0.441CysPhe: 0.441 ± 0.017	1.014CysGly: 1.014 ± 0.029	0.308CysHis: 0.308 ± 0.018	0.531CysIle: 0.531 ± 0.021	0.325CysLys: 0.325 ± 0.014	0.98CysLeu: 0.98 ± 0.027	0.223CysMet: 0.223 ± 0.012	0.329CysAsn: 0.329 ± 0.016	0.498CysPro: 0.498 ± 0.02	0.467CysGln: 0.467 ± 0.022	0.643CysArg: 0.643 ± 0.023	0.626CysSer: 0.626 ± 0.023	0.497CysThr: 0.497 ± 0.02	0.725CysVal: 0.725 ± 0.024	0.182CysTrp: 0.182 ± 0.01	0.321CysTyr: 0.321 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	5.505AspAla: 5.505 ± 0.073	0.52AspCys: 0.52 ± 0.02	3.344AspAsp: 3.344 ± 0.063	3.532AspGlu: 3.532 ± 0.058	2.117AspPhe: 2.117 ± 0.044	4.177AspGly: 4.177 ± 0.074	1.009AspHis: 1.009 ± 0.025	3.542AspIle: 3.542 ± 0.058	2.463AspLys: 2.463 ± 0.045	4.714AspLeu: 4.714 ± 0.065	1.342AspMet: 1.342 ± 0.032	2.435AspAsn: 2.435 ± 0.054	2.298AspPro: 2.298 ± 0.048	1.59AspGln: 1.59 ± 0.037	2.678AspArg: 2.678 ± 0.045	2.98AspSer: 2.98 ± 0.051	2.787AspThr: 2.787 ± 0.062	4.089AspVal: 4.089 ± 0.058	0.831AspTrp: 0.831 ± 0.028	1.879AspTyr: 1.879 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	5.209GluAla: 5.209 ± 0.069	0.488GluCys: 0.488 ± 0.02	2.278GluAsp: 2.278 ± 0.046	3.27GluGlu: 3.27 ± 0.057	1.841GluPhe: 1.841 ± 0.041	3.613GluGly: 3.613 ± 0.049	1.388GluHis: 1.388 ± 0.034	3.317GluIle: 3.317 ± 0.048	3.281GluLys: 3.281 ± 0.054	5.802GluLeu: 5.802 ± 0.075	1.866GluMet: 1.866 ± 0.04	2.399GluAsn: 2.399 ± 0.037	2.093GluPro: 2.093 ± 0.041	3.331GluGln: 3.331 ± 0.056	3.523GluArg: 3.523 ± 0.062	2.982GluSer: 2.982 ± 0.053	3.087GluThr: 3.087 ± 0.047	3.627GluVal: 3.627 ± 0.06	0.796GluTrp: 0.796 ± 0.025	1.425GluTyr: 1.425 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.62PheAla: 3.62 ± 0.061	0.51PheCys: 0.51 ± 0.021	2.361PheAsp: 2.361 ± 0.045	1.754PheGlu: 1.754 ± 0.035	1.599PhePhe: 1.599 ± 0.048	3.131PheGly: 3.131 ± 0.051	0.778PheHis: 0.778 ± 0.022	2.468PheIle: 2.468 ± 0.045	1.193PheLys: 1.193 ± 0.034	3.277PheLeu: 3.277 ± 0.047	0.953PheMet: 0.953 ± 0.029	1.683PheAsn: 1.683 ± 0.031	1.521PhePro: 1.521 ± 0.034	1.105PheGln: 1.105 ± 0.029	1.931PheArg: 1.931 ± 0.044	3.041PheSer: 3.041 ± 0.047	2.515PheThr: 2.515 ± 0.044	2.475PheVal: 2.475 ± 0.043	0.667PheTrp: 0.667 ± 0.025	1.158PheTyr: 1.158 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.343GlyAla: 6.343 ± 0.092	0.966GlyCys: 0.966 ± 0.027	4.036GlyAsp: 4.036 ± 0.065	4.533GlyGlu: 4.533 ± 0.051	3.229GlyPhe: 3.229 ± 0.055	5.621GlyGly: 5.621 ± 0.075	1.608GlyHis: 1.608 ± 0.038	5.049GlyIle: 5.049 ± 0.066	4.035GlyLys: 4.035 ± 0.059	7.438GlyLeu: 7.438 ± 0.084	2.407GlyMet: 2.407 ± 0.043	3.147GlyAsn: 3.147 ± 0.098	1.993GlyPro: 1.993 ± 0.037	2.978GlyGln: 2.978 ± 0.046	3.789GlyArg: 3.789 ± 0.059	4.49GlySer: 4.49 ± 0.101	4.35GlyThr: 4.35 ± 0.112	5.884GlyVal: 5.884 ± 0.069	1.3GlyTrp: 1.3 ± 0.034	2.604GlyTyr: 2.604 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	1.91HisAla: 1.91 ± 0.036	0.329HisCys: 0.329 ± 0.017	1.249HisAsp: 1.249 ± 0.028	1.107HisGlu: 1.107 ± 0.028	1.052HisPhe: 1.052 ± 0.028	1.721HisGly: 1.721 ± 0.036	0.778HisHis: 0.778 ± 0.023	1.258HisIle: 1.258 ± 0.028	0.747HisLys: 0.747 ± 0.025	2.136HisLeu: 2.136 ± 0.038	0.526HisMet: 0.526 ± 0.02	0.852HisAsn: 0.852 ± 0.022	1.262HisPro: 1.262 ± 0.032	1.098HisGln: 1.098 ± 0.031	1.258HisArg: 1.258 ± 0.032	1.245HisSer: 1.245 ± 0.029	1.107HisThr: 1.107 ± 0.027	1.296HisVal: 1.296 ± 0.033	0.422HisTrp: 0.422 ± 0.016	0.892HisTyr: 0.892 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.355IleAla: 6.355 ± 0.066	0.641IleCys: 0.641 ± 0.022	3.616IleAsp: 3.616 ± 0.055	3.169IleGlu: 3.169 ± 0.05	1.966IlePhe: 1.966 ± 0.042	4.47IleGly: 4.47 ± 0.07	1.195IleHis: 1.195 ± 0.029	3.352IleIle: 3.352 ± 0.057	2.249IleLys: 2.249 ± 0.052	4.875IleLeu: 4.875 ± 0.061	1.209IleMet: 1.209 ± 0.032	2.76IleAsn: 2.76 ± 0.053	2.69IlePro: 2.69 ± 0.051	1.845IleGln: 1.845 ± 0.037	3.073IleArg: 3.073 ± 0.041	3.894IleSer: 3.894 ± 0.052	3.812IleThr: 3.812 ± 0.055	3.87IleVal: 3.87 ± 0.058	0.711IleTrp: 0.711 ± 0.022	1.562IleTyr: 1.562 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.291LysAla: 4.291 ± 0.065	0.281LysCys: 0.281 ± 0.015	2.053LysAsp: 2.053 ± 0.045	2.434LysGlu: 2.434 ± 0.047	1.082LysPhe: 1.082 ± 0.029	2.935LysGly: 2.935 ± 0.052	0.869LysHis: 0.869 ± 0.026	2.271LysIle: 2.271 ± 0.041	2.199LysLys: 2.199 ± 0.056	4.076LysLeu: 4.076 ± 0.065	1.214LysMet: 1.214 ± 0.029	1.742LysAsn: 1.742 ± 0.04	2.112LysPro: 2.112 ± 0.04	1.907LysGln: 1.907 ± 0.033	2.527LysArg: 2.527 ± 0.04	2.289LysSer: 2.289 ± 0.039	2.648LysThr: 2.648 ± 0.054	2.843LysVal: 2.843 ± 0.051	0.502LysTrp: 0.502 ± 0.02	1.128LysTyr: 1.128 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.002LeuAla: 11.002 ± 0.106	1.192LeuCys: 1.192 ± 0.029	5.364LeuAsp: 5.364 ± 0.071	5.371LeuGlu: 5.371 ± 0.07	4.13LeuPhe: 4.13 ± 0.066	7.115LeuGly: 7.115 ± 0.086	2.278LeuHis: 2.278 ± 0.042	5.672LeuIle: 5.672 ± 0.068	4.446LeuLys: 4.446 ± 0.058	11.614LeuLeu: 11.614 ± 0.14	2.889LeuMet: 2.889 ± 0.05	4.401LeuAsn: 4.401 ± 0.067	5.553LeuPro: 5.553 ± 0.08	4.039LeuGln: 4.039 ± 0.064	6.091LeuArg: 6.091 ± 0.065	7.409LeuSer: 7.409 ± 0.088	6.664LeuThr: 6.664 ± 0.092	7.029LeuVal: 7.029 ± 0.075	1.49LeuTrp: 1.49 ± 0.032	2.518LeuTyr: 2.518 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.875MetAla: 2.875 ± 0.043	0.195MetCys: 0.195 ± 0.012	1.211MetAsp: 1.211 ± 0.029	1.283MetGlu: 1.283 ± 0.031	0.849MetPhe: 0.849 ± 0.026	1.879MetGly: 1.879 ± 0.043	0.517MetHis: 0.517 ± 0.019	1.462MetIle: 1.462 ± 0.032	1.416MetLys: 1.416 ± 0.031	3.126MetLeu: 3.126 ± 0.047	0.931MetMet: 0.931 ± 0.028	1.061MetAsn: 1.061 ± 0.028	1.309MetPro: 1.309 ± 0.033	1.217MetGln: 1.217 ± 0.031	1.49MetArg: 1.49 ± 0.029	1.874MetSer: 1.874 ± 0.037	1.849MetThr: 1.849 ± 0.033	1.928MetVal: 1.928 ± 0.038	0.254MetTrp: 0.254 ± 0.013	0.524MetTyr: 0.524 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.781AsnAla: 3.781 ± 0.069	0.341AsnCys: 0.341 ± 0.017	2.198AsnAsp: 2.198 ± 0.044	1.957AsnGlu: 1.957 ± 0.036	1.275AsnPhe: 1.275 ± 0.03	3.404AsnGly: 3.404 ± 0.08	0.843AsnHis: 0.843 ± 0.025	2.402AsnIle: 2.402 ± 0.041	1.514AsnLys: 1.514 ± 0.036	3.531AsnLeu: 3.531 ± 0.055	0.925AsnMet: 0.925 ± 0.027	1.748AsnAsn: 1.748 ± 0.051	2.131AsnPro: 2.131 ± 0.035	1.563AsnGln: 1.563 ± 0.034	2.092AsnArg: 2.092 ± 0.038	2.213AsnSer: 2.213 ± 0.067	2.247AsnThr: 2.247 ± 0.061	2.701AsnVal: 2.701 ± 0.044	0.591AsnTrp: 0.591 ± 0.023	1.227AsnTyr: 1.227 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.539ProAla: 4.539 ± 0.067	0.381ProCys: 0.381 ± 0.017	2.962ProAsp: 2.962 ± 0.054	3.318ProGlu: 3.318 ± 0.047	1.77ProPhe: 1.77 ± 0.036	3.532ProGly: 3.532 ± 0.05	1.027ProHis: 1.027 ± 0.026	1.639ProIle: 1.639 ± 0.044	1.512ProLys: 1.512 ± 0.037	4.982ProLeu: 4.982 ± 0.072	1.042ProMet: 1.042 ± 0.029	1.22ProAsn: 1.22 ± 0.024	1.705ProPro: 1.705 ± 0.036	2.181ProGln: 2.181 ± 0.048	1.954ProArg: 1.954 ± 0.044	2.202ProSer: 2.202 ± 0.045	2.095ProThr: 2.095 ± 0.048	4.169ProVal: 4.169 ± 0.069	0.75ProTrp: 0.75 ± 0.024	1.14ProTyr: 1.14 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.487GlnAla: 4.487 ± 0.068	0.367GlnCys: 0.367 ± 0.018	1.868GlnAsp: 1.868 ± 0.032	2.193GlnGlu: 2.193 ± 0.048	1.497GlnPhe: 1.497 ± 0.033	2.989GlnGly: 2.989 ± 0.046	1.189GlnHis: 1.189 ± 0.031	2.268GlnIle: 2.268 ± 0.045	1.836GlnLys: 1.836 ± 0.04	4.902GlnLeu: 4.902 ± 0.068	1.187GlnMet: 1.187 ± 0.026	1.535GlnAsn: 1.535 ± 0.036	2.132GlnPro: 2.132 ± 0.047	3.265GlnGln: 3.265 ± 0.064	2.949GlnArg: 2.949 ± 0.057	2.341GlnSer: 2.341 ± 0.038	2.284GlnThr: 2.284 ± 0.043	2.949GlnVal: 2.949 ± 0.051	0.668GlnTrp: 0.668 ± 0.024	1.159GlnTyr: 1.159 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	4.504ArgAla: 4.504 ± 0.067	0.577ArgCys: 0.577 ± 0.021	3.186ArgAsp: 3.186 ± 0.05	3.755ArgGlu: 3.755 ± 0.064	2.559ArgPhe: 2.559 ± 0.044	3.473ArgGly: 3.473 ± 0.054	1.607ArgHis: 1.607 ± 0.034	3.374ArgIle: 3.374 ± 0.05	2.375ArgLys: 2.375 ± 0.043	6.369ArgLeu: 6.369 ± 0.089	1.594ArgMet: 1.594 ± 0.034	2.134ArgAsn: 2.134 ± 0.041	2.19ArgPro: 2.19 ± 0.044	3.044ArgGln: 3.044 ± 0.055	3.534ArgArg: 3.534 ± 0.059	2.766ArgSer: 2.766 ± 0.043	2.566ArgThr: 2.566 ± 0.041	3.851ArgVal: 3.851 ± 0.058	1.009ArgTrp: 1.009 ± 0.032	2.15ArgTyr: 2.15 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.739SerAla: 5.739 ± 0.077	0.578SerCys: 0.578 ± 0.026	3.218SerAsp: 3.218 ± 0.047	3.182SerGlu: 3.182 ± 0.045	2.27SerPhe: 2.27 ± 0.042	5.77SerGly: 5.77 ± 0.12	1.446SerHis: 1.446 ± 0.029	3.042SerIle: 3.042 ± 0.039	1.963SerLys: 1.963 ± 0.039	6.708SerLeu: 6.708 ± 0.076	1.529SerMet: 1.529 ± 0.032	2.027SerAsn: 2.027 ± 0.047	2.671SerPro: 2.671 ± 0.049	2.644SerGln: 2.644 ± 0.046	3.566SerArg: 3.566 ± 0.055	3.642SerSer: 3.642 ± 0.066	3.128SerThr: 3.128 ± 0.056	4.421SerVal: 4.421 ± 0.064	0.947SerTrp: 0.947 ± 0.028	1.627SerTyr: 1.627 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.493ThrAla: 5.493 ± 0.094	0.519ThrCys: 0.519 ± 0.019	3.036ThrAsp: 3.036 ± 0.064	2.739ThrGlu: 2.739 ± 0.048	2.072ThrPhe: 2.072 ± 0.044	5.195ThrGly: 5.195 ± 0.098	1.216ThrHis: 1.216 ± 0.03	3.132ThrIle: 3.132 ± 0.06	1.51ThrLys: 1.51 ± 0.035	7.601ThrLeu: 7.601 ± 0.097	1.178ThrMet: 1.178 ± 0.027	1.643ThrAsn: 1.643 ± 0.043	3.334ThrPro: 3.334 ± 0.063	2.27ThrGln: 2.27 ± 0.046	3.242ThrArg: 3.242 ± 0.05	3.103ThrSer: 3.103 ± 0.057	3.281ThrThr: 3.281 ± 0.082	4.377ThrVal: 4.377 ± 0.109	0.895ThrTrp: 0.895 ± 0.029	1.202ThrTyr: 1.202 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	7.05ValAla: 7.05 ± 0.07	0.733ValCys: 0.733 ± 0.027	3.839ValAsp: 3.839 ± 0.071	3.901ValGlu: 3.901 ± 0.058	2.538ValPhe: 2.538 ± 0.045	4.8ValGly: 4.8 ± 0.073	1.27ValHis: 1.27 ± 0.03	4.662ValIle: 4.662 ± 0.063	3.036ValLys: 3.036 ± 0.057	7.305ValLeu: 7.305 ± 0.081	2.246ValMet: 2.246 ± 0.035	2.951ValAsn: 2.951 ± 0.054	3.031ValPro: 3.031 ± 0.05	2.424ValGln: 2.424 ± 0.041	3.732ValArg: 3.732 ± 0.052	4.689ValSer: 4.689 ± 0.063	4.716ValThr: 4.716 ± 0.09	5.669ValVal: 5.669 ± 0.073	0.964ValTrp: 0.964 ± 0.025	1.761ValTyr: 1.761 ± 0.034	0.001ValXaa: 0.001 ± 0.001
Trp	1.018TrpAla: 1.018 ± 0.029	0.204TrpCys: 0.204 ± 0.012	0.671TrpAsp: 0.671 ± 0.025	0.624TrpGlu: 0.624 ± 0.021	0.715TrpPhe: 0.715 ± 0.023	0.89TrpGly: 0.89 ± 0.027	0.437TrpHis: 0.437 ± 0.018	0.762TrpIle: 0.762 ± 0.026	0.551TrpLys: 0.551 ± 0.02	2.301TrpLeu: 2.301 ± 0.048	0.455TrpMet: 0.455 ± 0.018	0.513TrpAsn: 0.513 ± 0.019	0.666TrpPro: 0.666 ± 0.025	1.169TrpGln: 1.169 ± 0.029	1.089TrpArg: 1.089 ± 0.034	0.884TrpSer: 0.884 ± 0.03	0.654TrpThr: 0.654 ± 0.026	0.976TrpVal: 0.976 ± 0.029	0.257TrpTrp: 0.257 ± 0.015	0.453TrpTyr: 0.453 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.435TyrAla: 2.435 ± 0.041	0.375TyrCys: 0.375 ± 0.014	1.583TyrAsp: 1.583 ± 0.035	1.187TyrGlu: 1.187 ± 0.029	1.138TyrPhe: 1.138 ± 0.029	2.217TyrGly: 2.217 ± 0.038	0.682TyrHis: 0.682 ± 0.023	1.4TyrIle: 1.4 ± 0.027	0.936TyrLys: 0.936 ± 0.032	2.92TyrLeu: 2.92 ± 0.051	0.593TyrMet: 0.593 ± 0.018	1.06TyrAsn: 1.06 ± 0.032	1.299TyrPro: 1.299 ± 0.033	1.538TyrGln: 1.538 ± 0.034	1.871TyrArg: 1.871 ± 0.034	1.723TyrSer: 1.723 ± 0.031	1.539TyrThr: 1.539 ± 0.041	1.715TyrVal: 1.715 ± 0.038	0.443TyrTrp: 0.443 ± 0.019	0.929TyrTyr: 0.929 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4729 proteins (1449508 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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