Amino acid dipepetide frequency for Fomitiporia mediterranea (strain MF3/22) (Grapevine white-rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.234AlaAla: 7.234 ± 0.355
1.311AlaCys: 1.311 ± 0.116
4.068AlaAsp: 4.068 ± 0.176
4.421AlaGlu: 4.421 ± 0.218
3.5AlaPhe: 3.5 ± 0.172
4.612AlaGly: 4.612 ± 0.188
2.003AlaHis: 2.003 ± 0.125
4.897AlaIle: 4.897 ± 0.251
3.66AlaLys: 3.66 ± 0.246
8.452AlaLeu: 8.452 ± 0.362
1.756AlaMet: 1.756 ± 0.107
2.931AlaAsn: 2.931 ± 0.164
3.679AlaPro: 3.679 ± 0.213
3.023AlaGln: 3.023 ± 0.149
4.786AlaArg: 4.786 ± 0.179
6.727AlaSer: 6.727 ± 0.254
4.86AlaThr: 4.86 ± 0.194
5.453AlaVal: 5.453 ± 0.226
0.81AlaTrp: 0.81 ± 0.075
1.941AlaTyr: 1.941 ± 0.105
0.0AlaXaa: 0.0 ± 0.0
Cys
1.336CysAla: 1.336 ± 0.104
0.501CysCys: 0.501 ± 0.083
0.773CysAsp: 0.773 ± 0.071
0.618CysGlu: 0.618 ± 0.06
0.544CysPhe: 0.544 ± 0.062
0.971CysGly: 0.971 ± 0.076
0.464CysHis: 0.464 ± 0.059
0.853CysIle: 0.853 ± 0.073
0.859CysLys: 0.859 ± 0.088
1.305CysLeu: 1.305 ± 0.095
0.408CysMet: 0.408 ± 0.047
0.705CysAsn: 0.705 ± 0.068
1.063CysPro: 1.063 ± 0.118
0.42CysGln: 0.42 ± 0.047
0.934CysArg: 0.934 ± 0.09
1.057CysSer: 1.057 ± 0.102
0.995CysThr: 0.995 ± 0.092
0.872CysVal: 0.872 ± 0.072
0.278CysTrp: 0.278 ± 0.04
0.396CysTyr: 0.396 ± 0.053
0.0CysXaa: 0.0 ± 0.0
Asp
4.371AspAla: 4.371 ± 0.219
0.674AspCys: 0.674 ± 0.065
3.456AspAsp: 3.456 ± 0.155
4.866AspGlu: 4.866 ± 0.261
2.016AspPhe: 2.016 ± 0.095
4.198AspGly: 4.198 ± 0.194
1.181AspHis: 1.181 ± 0.091
3.011AspIle: 3.011 ± 0.134
2.813AspLys: 2.813 ± 0.149
5.75AspLeu: 5.75 ± 0.265
1.119AspMet: 1.119 ± 0.089
1.911AspAsn: 1.911 ± 0.12
2.832AspPro: 2.832 ± 0.152
1.54AspGln: 1.54 ± 0.115
3.308AspArg: 3.308 ± 0.2
4.291AspSer: 4.291 ± 0.186
3.363AspThr: 3.363 ± 0.146
3.394AspVal: 3.394 ± 0.16
0.866AspTrp: 0.866 ± 0.086
1.397AspTyr: 1.397 ± 0.091
0.0AspXaa: 0.0 ± 0.0
Glu
5.509GluAla: 5.509 ± 0.221
0.965GluCys: 0.965 ± 0.082
5.008GluAsp: 5.008 ± 0.257
5.707GluGlu: 5.707 ± 0.244
1.966GluPhe: 1.966 ± 0.115
4.347GluGly: 4.347 ± 0.226
1.744GluHis: 1.744 ± 0.114
2.986GluIle: 2.986 ± 0.149
3.802GluLys: 3.802 ± 0.307
6.449GluLeu: 6.449 ± 0.272
1.274GluMet: 1.274 ± 0.092
2.133GluAsn: 2.133 ± 0.111
2.3GluPro: 2.3 ± 0.121
2.665GluGln: 2.665 ± 0.165
4.538GluArg: 4.538 ± 0.198
3.852GluSer: 3.852 ± 0.19
3.234GluThr: 3.234 ± 0.15
3.469GluVal: 3.469 ± 0.149
0.909GluTrp: 0.909 ± 0.075
1.552GluTyr: 1.552 ± 0.1
0.0GluXaa: 0.0 ± 0.0
Phe
2.986PheAla: 2.986 ± 0.159
0.649PheCys: 0.649 ± 0.063
2.479PheAsp: 2.479 ± 0.134
2.634PheGlu: 2.634 ± 0.18
1.496PhePhe: 1.496 ± 0.126
2.275PheGly: 2.275 ± 0.135
1.057PheHis: 1.057 ± 0.076
1.793PheIle: 1.793 ± 0.119
1.88PheLys: 1.88 ± 0.136
3.431PheLeu: 3.431 ± 0.169
0.563PheMet: 0.563 ± 0.061
1.682PheAsn: 1.682 ± 0.11
1.861PhePro: 1.861 ± 0.131
1.101PheGln: 1.101 ± 0.077
2.152PheArg: 2.152 ± 0.112
3.234PheSer: 3.234 ± 0.182
2.059PheThr: 2.059 ± 0.125
2.38PheVal: 2.38 ± 0.127
0.526PheTrp: 0.526 ± 0.062
1.082PheTyr: 1.082 ± 0.1
0.0PheXaa: 0.0 ± 0.0
Gly
4.13GlyAla: 4.13 ± 0.18
0.816GlyCys: 0.816 ± 0.075
2.788GlyAsp: 2.788 ± 0.119
3.413GlyGlu: 3.413 ± 0.186
2.17GlyPhe: 2.17 ± 0.126
3.802GlyGly: 3.802 ± 0.249
2.424GlyHis: 2.424 ± 0.203
3.11GlyIle: 3.11 ± 0.125
2.974GlyLys: 2.974 ± 0.145
5.187GlyLeu: 5.187 ± 0.185
1.329GlyMet: 1.329 ± 0.088
2.275GlyAsn: 2.275 ± 0.116
3.011GlyPro: 3.011 ± 0.141
2.306GlyGln: 2.306 ± 0.167
3.889GlyArg: 3.889 ± 0.178
5.577GlySer: 5.577 ± 0.209
3.734GlyThr: 3.734 ± 0.151
3.357GlyVal: 3.357 ± 0.154
1.107GlyTrp: 1.107 ± 0.087
1.595GlyTyr: 1.595 ± 0.12
0.0GlyXaa: 0.0 ± 0.0
His
2.22HisAla: 2.22 ± 0.121
0.655HisCys: 0.655 ± 0.064
1.255HisAsp: 1.255 ± 0.091
1.298HisGlu: 1.298 ± 0.097
0.909HisPhe: 0.909 ± 0.068
1.923HisGly: 1.923 ± 0.134
1.187HisHis: 1.187 ± 0.15
1.521HisIle: 1.521 ± 0.094
1.131HisLys: 1.131 ± 0.104
2.374HisLeu: 2.374 ± 0.134
0.445HisMet: 0.445 ± 0.05
1.082HisAsn: 1.082 ± 0.074
2.343HisPro: 2.343 ± 0.239
0.662HisGln: 0.662 ± 0.063
2.189HisArg: 2.189 ± 0.16
2.523HisSer: 2.523 ± 0.15
2.053HisThr: 2.053 ± 0.123
1.36HisVal: 1.36 ± 0.1
0.346HisTrp: 0.346 ± 0.043
0.884HisTyr: 0.884 ± 0.09
0.0HisXaa: 0.0 ± 0.0
Ile
3.963IleAla: 3.963 ± 0.182
0.884IleCys: 0.884 ± 0.082
2.702IleAsp: 2.702 ± 0.12
3.061IleGlu: 3.061 ± 0.167
1.849IlePhe: 1.849 ± 0.136
3.159IleGly: 3.159 ± 0.148
1.441IleHis: 1.441 ± 0.104
2.745IleIle: 2.745 ± 0.177
2.343IleLys: 2.343 ± 0.15
4.847IleLeu: 4.847 ± 0.204
0.971IleMet: 0.971 ± 0.077
2.096IleAsn: 2.096 ± 0.134
2.801IlePro: 2.801 ± 0.133
1.793IleGln: 1.793 ± 0.109
3.227IleArg: 3.227 ± 0.148
3.926IleSer: 3.926 ± 0.148
2.56IleThr: 2.56 ± 0.15
3.852IleVal: 3.852 ± 0.184
0.748IleTrp: 0.748 ± 0.073
1.23IleTyr: 1.23 ± 0.091
0.0IleXaa: 0.0 ± 0.0
Lys
3.586LysAla: 3.586 ± 0.165
0.662LysCys: 0.662 ± 0.07
2.702LysAsp: 2.702 ± 0.17
4.353LysGlu: 4.353 ± 0.393
1.175LysPhe: 1.175 ± 0.082
2.733LysGly: 2.733 ± 0.154
1.484LysHis: 1.484 ± 0.108
2.096LysIle: 2.096 ± 0.106
3.061LysLys: 3.061 ± 0.2
4.551LysLeu: 4.551 ± 0.215
0.983LysMet: 0.983 ± 0.072
1.756LysAsn: 1.756 ± 0.099
2.065LysPro: 2.065 ± 0.124
1.756LysGln: 1.756 ± 0.101
3.734LysArg: 3.734 ± 0.165
3.104LysSer: 3.104 ± 0.153
2.387LysThr: 2.387 ± 0.109
2.999LysVal: 2.999 ± 0.191
0.501LysTrp: 0.501 ± 0.06
1.62LysTyr: 1.62 ± 0.119
0.0LysXaa: 0.0 ± 0.0
Leu
8.656LeuAla: 8.656 ± 0.281
1.558LeuCys: 1.558 ± 0.114
6.461LeuAsp: 6.461 ± 0.286
6.226LeuGlu: 6.226 ± 0.386
3.673LeuPhe: 3.673 ± 0.196
5.058LeuGly: 5.058 ± 0.187
2.745LeuHis: 2.745 ± 0.167
4.105LeuIle: 4.105 ± 0.175
4.161LeuLys: 4.161 ± 0.193
9.287LeuLeu: 9.287 ± 0.315
1.632LeuMet: 1.632 ± 0.105
3.92LeuAsn: 3.92 ± 0.182
5.336LeuPro: 5.336 ± 0.221
4.625LeuGln: 4.625 ± 0.192
6.325LeuArg: 6.325 ± 0.248
8.285LeuSer: 8.285 ± 0.243
5.274LeuThr: 5.274 ± 0.209
5.119LeuVal: 5.119 ± 0.236
1.342LeuTrp: 1.342 ± 0.094
2.696LeuTyr: 2.696 ± 0.129
0.0LeuXaa: 0.0 ± 0.0
Met
1.249MetAla: 1.249 ± 0.087
0.334MetCys: 0.334 ± 0.043
1.379MetAsp: 1.379 ± 0.09
1.107MetGlu: 1.107 ± 0.068
0.637MetPhe: 0.637 ± 0.063
0.946MetGly: 0.946 ± 0.094
0.575MetHis: 0.575 ± 0.063
0.927MetIle: 0.927 ± 0.084
0.94MetLys: 0.94 ± 0.077
1.805MetLeu: 1.805 ± 0.122
0.458MetMet: 0.458 ± 0.064
0.853MetAsn: 0.853 ± 0.07
1.199MetPro: 1.199 ± 0.104
1.039MetGln: 1.039 ± 0.091
1.41MetArg: 1.41 ± 0.07
1.923MetSer: 1.923 ± 0.123
1.02MetThr: 1.02 ± 0.096
1.255MetVal: 1.255 ± 0.088
0.229MetTrp: 0.229 ± 0.037
0.742MetTyr: 0.742 ± 0.071
0.0MetXaa: 0.0 ± 0.0
Asn
3.66AsnAla: 3.66 ± 0.175
0.6AsnCys: 0.6 ± 0.059
1.781AsnAsp: 1.781 ± 0.111
2.362AsnGlu: 2.362 ± 0.125
1.36AsnPhe: 1.36 ± 0.109
2.486AsnGly: 2.486 ± 0.163
1.002AsnHis: 1.002 ± 0.08
2.275AsnIle: 2.275 ± 0.123
1.657AsnLys: 1.657 ± 0.136
4.143AsnLeu: 4.143 ± 0.254
0.767AsnMet: 0.767 ± 0.07
2.275AsnAsn: 2.275 ± 0.186
1.75AsnPro: 1.75 ± 0.13
1.434AsnGln: 1.434 ± 0.103
2.288AsnArg: 2.288 ± 0.121
3.357AsnSer: 3.357 ± 0.166
2.337AsnThr: 2.337 ± 0.158
2.393AsnVal: 2.393 ± 0.111
0.482AsnTrp: 0.482 ± 0.052
1.131AsnTyr: 1.131 ± 0.1
0.0AsnXaa: 0.0 ± 0.0
Pro
3.53ProAla: 3.53 ± 0.185
0.575ProCys: 0.575 ± 0.07
3.512ProAsp: 3.512 ± 0.18
3.895ProGlu: 3.895 ± 0.165
2.646ProPhe: 2.646 ± 0.139
2.844ProGly: 2.844 ± 0.144
1.187ProHis: 1.187 ± 0.095
2.127ProIle: 2.127 ± 0.14
2.226ProLys: 2.226 ± 0.114
4.309ProLeu: 4.309 ± 0.195
0.927ProMet: 0.927 ± 0.082
2.51ProAsn: 2.51 ± 0.162
3.963ProPro: 3.963 ± 0.28
1.935ProGln: 1.935 ± 0.122
3.221ProArg: 3.221 ± 0.175
5.725ProSer: 5.725 ± 0.332
3.642ProThr: 3.642 ± 0.172
3.679ProVal: 3.679 ± 0.15
0.501ProTrp: 0.501 ± 0.067
1.521ProTyr: 1.521 ± 0.115
0.0ProXaa: 0.0 ± 0.0
Gln
3.456GlnAla: 3.456 ± 0.188
0.606GlnCys: 0.606 ± 0.072
1.546GlnAsp: 1.546 ± 0.103
1.867GlnGlu: 1.867 ± 0.112
1.206GlnPhe: 1.206 ± 0.091
2.077GlnGly: 2.077 ± 0.116
1.422GlnHis: 1.422 ± 0.123
1.824GlnIle: 1.824 ± 0.115
1.638GlnLys: 1.638 ± 0.114
3.901GlnLeu: 3.901 ± 0.161
0.717GlnMet: 0.717 ± 0.071
1.583GlnAsn: 1.583 ± 0.093
2.065GlnPro: 2.065 ± 0.142
2.059GlnGln: 2.059 ± 0.193
2.226GlnArg: 2.226 ± 0.133
3.314GlnSer: 3.314 ± 0.164
2.64GlnThr: 2.64 ± 0.191
1.966GlnVal: 1.966 ± 0.114
0.501GlnTrp: 0.501 ± 0.063
1.162GlnTyr: 1.162 ± 0.098
0.0GlnXaa: 0.0 ± 0.0
Arg
5.583ArgAla: 5.583 ± 0.248
0.822ArgCys: 0.822 ± 0.07
3.129ArgAsp: 3.129 ± 0.148
3.988ArgGlu: 3.988 ± 0.192
3.079ArgPhe: 3.079 ± 0.251
3.388ArgGly: 3.388 ± 0.181
1.682ArgHis: 1.682 ± 0.111
3.054ArgIle: 3.054 ± 0.176
3.116ArgLys: 3.116 ± 0.158
5.249ArgLeu: 5.249 ± 0.2
1.317ArgMet: 1.317 ± 0.087
2.244ArgAsn: 2.244 ± 0.113
3.537ArgPro: 3.537 ± 0.172
2.572ArgGln: 2.572 ± 0.118
5.305ArgArg: 5.305 ± 0.245
6.146ArgSer: 6.146 ± 0.308
4.007ArgThr: 4.007 ± 0.16
3.419ArgVal: 3.419 ± 0.158
1.002ArgTrp: 1.002 ± 0.087
1.948ArgTyr: 1.948 ± 0.137
0.0ArgXaa: 0.0 ± 0.0
Ser
6.467SerAla: 6.467 ± 0.251
0.983SerCys: 0.983 ± 0.082
4.575SerAsp: 4.575 ± 0.166
4.47SerGlu: 4.47 ± 0.196
2.9SerPhe: 2.9 ± 0.157
4.977SerGly: 4.977 ± 0.182
2.263SerHis: 2.263 ± 0.142
4.353SerIle: 4.353 ± 0.158
3.506SerLys: 3.506 ± 0.158
9.083SerLeu: 9.083 ± 0.319
1.923SerMet: 1.923 ± 0.114
3.394SerAsn: 3.394 ± 0.155
5.268SerPro: 5.268 ± 0.282
3.017SerGln: 3.017 ± 0.163
5.163SerArg: 5.163 ± 0.205
9.849SerSer: 9.849 ± 0.412
6.14SerThr: 6.14 ± 0.239
5.466SerVal: 5.466 ± 0.215
0.779SerTrp: 0.779 ± 0.075
1.805SerTyr: 1.805 ± 0.113
0.0SerXaa: 0.0 ± 0.0
Thr
4.538ThrAla: 4.538 ± 0.199
0.884ThrCys: 0.884 ± 0.087
2.968ThrAsp: 2.968 ± 0.131
3.357ThrGlu: 3.357 ± 0.147
2.115ThrPhe: 2.115 ± 0.127
3.24ThrGly: 3.24 ± 0.152
1.57ThrHis: 1.57 ± 0.112
3.122ThrIle: 3.122 ± 0.157
2.405ThrLys: 2.405 ± 0.126
6.436ThrLeu: 6.436 ± 0.226
1.249ThrMet: 1.249 ± 0.084
2.448ThrAsn: 2.448 ± 0.134
4.013ThrPro: 4.013 ± 0.208
2.084ThrGln: 2.084 ± 0.117
4.007ThrArg: 4.007 ± 0.207
5.552ThrSer: 5.552 ± 0.207
4.526ThrThr: 4.526 ± 0.224
3.87ThrVal: 3.87 ± 0.158
0.847ThrTrp: 0.847 ± 0.073
1.224ThrTyr: 1.224 ± 0.096
0.0ThrXaa: 0.0 ± 0.0
Val
4.631ValAla: 4.631 ± 0.18
0.971ValCys: 0.971 ± 0.072
3.388ValAsp: 3.388 ± 0.152
4.334ValGlu: 4.334 ± 0.21
2.523ValPhe: 2.523 ± 0.133
3.561ValGly: 3.561 ± 0.164
1.929ValHis: 1.929 ± 0.103
3.135ValIle: 3.135 ± 0.157
2.943ValLys: 2.943 ± 0.16
5.917ValLeu: 5.917 ± 0.206
1.274ValMet: 1.274 ± 0.091
2.238ValAsn: 2.238 ± 0.105
3.506ValPro: 3.506 ± 0.167
2.424ValGln: 2.424 ± 0.123
3.376ValArg: 3.376 ± 0.169
4.773ValSer: 4.773 ± 0.181
3.098ValThr: 3.098 ± 0.148
4.433ValVal: 4.433 ± 0.182
0.927ValTrp: 0.927 ± 0.094
1.744ValTyr: 1.744 ± 0.108
0.0ValXaa: 0.0 ± 0.0
Trp
0.934TrpAla: 0.934 ± 0.083
0.284TrpCys: 0.284 ± 0.044
0.872TrpAsp: 0.872 ± 0.087
0.748TrpGlu: 0.748 ± 0.061
0.569TrpPhe: 0.569 ± 0.088
0.699TrpGly: 0.699 ± 0.067
0.266TrpHis: 0.266 ± 0.041
0.736TrpIle: 0.736 ± 0.069
0.791TrpLys: 0.791 ± 0.085
1.218TrpLeu: 1.218 ± 0.106
0.334TrpMet: 0.334 ± 0.051
0.396TrpAsn: 0.396 ± 0.053
0.569TrpPro: 0.569 ± 0.073
0.464TrpGln: 0.464 ± 0.054
0.921TrpArg: 0.921 ± 0.093
1.082TrpSer: 1.082 ± 0.095
0.897TrpThr: 0.897 ± 0.078
0.921TrpVal: 0.921 ± 0.078
0.408TrpTrp: 0.408 ± 0.054
0.458TrpTyr: 0.458 ± 0.059
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.084TyrAla: 2.084 ± 0.126
0.618TyrCys: 0.618 ± 0.072
1.509TyrAsp: 1.509 ± 0.096
1.682TyrGlu: 1.682 ± 0.105
0.989TyrPhe: 0.989 ± 0.083
1.7TyrGly: 1.7 ± 0.116
0.736TyrHis: 0.736 ± 0.086
1.527TyrIle: 1.527 ± 0.109
1.397TyrLys: 1.397 ± 0.102
2.788TyrLeu: 2.788 ± 0.188
0.581TyrMet: 0.581 ± 0.055
1.107TyrAsn: 1.107 ± 0.082
1.317TyrPro: 1.317 ± 0.097
0.859TyrGln: 0.859 ± 0.077
1.595TyrArg: 1.595 ± 0.104
2.084TyrSer: 2.084 ± 0.117
1.632TyrThr: 1.632 ± 0.096
1.465TyrVal: 1.465 ± 0.089
0.458TyrTrp: 0.458 ± 0.056
1.033TyrTyr: 1.033 ± 0.088
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 531 proteins (161738 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski