Amino acid dipepetide frequency for Fusarium flagelliforme

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.357AlaAla: 8.357 ± 0.067	1.096AlaCys: 1.096 ± 0.016	4.191AlaAsp: 4.191 ± 0.027	5.086AlaGlu: 5.086 ± 0.048	3.099AlaPhe: 3.099 ± 0.024	5.48AlaGly: 5.48 ± 0.036	1.661AlaHis: 1.661 ± 0.015	4.408AlaIle: 4.408 ± 0.027	4.234AlaLys: 4.234 ± 0.035	7.431AlaLeu: 7.431 ± 0.04	2.0AlaMet: 2.0 ± 0.019	2.939AlaAsn: 2.939 ± 0.021	4.768AlaPro: 4.768 ± 0.044	3.301AlaGln: 3.301 ± 0.029	4.459AlaArg: 4.459 ± 0.03	6.914AlaSer: 6.914 ± 0.04	5.254AlaThr: 5.254 ± 0.033	5.212AlaVal: 5.212 ± 0.035	1.188AlaTrp: 1.188 ± 0.015	2.118AlaTyr: 2.118 ± 0.02	0.001AlaXaa: 0.001 ± 0.0
Cys	0.933CysAla: 0.933 ± 0.015	0.25CysCys: 0.25 ± 0.008	0.713CysAsp: 0.713 ± 0.011	0.639CysGlu: 0.639 ± 0.011	0.573CysPhe: 0.573 ± 0.01	0.952CysGly: 0.952 ± 0.015	0.33CysHis: 0.33 ± 0.007	0.756CysIle: 0.756 ± 0.012	0.585CysLys: 0.585 ± 0.01	1.248CysLeu: 1.248 ± 0.016	0.28CysMet: 0.28 ± 0.007	0.47CysAsn: 0.47 ± 0.009	0.672CysPro: 0.672 ± 0.013	0.488CysGln: 0.488 ± 0.01	0.723CysArg: 0.723 ± 0.011	0.903CysSer: 0.903 ± 0.012	0.73CysThr: 0.73 ± 0.014	0.823CysVal: 0.823 ± 0.015	0.225CysTrp: 0.225 ± 0.006	0.384CysTyr: 0.384 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.689AspAla: 4.689 ± 0.029	0.696AspCys: 0.696 ± 0.012	4.639AspAsp: 4.639 ± 0.039	4.78AspGlu: 4.78 ± 0.036	2.334AspPhe: 2.334 ± 0.022	4.12AspGly: 4.12 ± 0.029	1.32AspHis: 1.32 ± 0.015	3.245AspIle: 3.245 ± 0.023	2.815AspLys: 2.815 ± 0.024	5.132AspLeu: 5.132 ± 0.033	1.397AspMet: 1.397 ± 0.016	2.134AspAsn: 2.134 ± 0.021	3.325AspPro: 3.325 ± 0.028	2.0AspGln: 2.0 ± 0.019	3.015AspArg: 3.015 ± 0.029	4.297AspSer: 4.297 ± 0.032	3.134AspThr: 3.134 ± 0.026	3.732AspVal: 3.732 ± 0.024	0.979AspTrp: 0.979 ± 0.013	1.667AspTyr: 1.667 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.56GluAla: 5.56 ± 0.048	0.677GluCys: 0.677 ± 0.012	4.439GluAsp: 4.439 ± 0.035	5.598GluGlu: 5.598 ± 0.057	2.03GluPhe: 2.03 ± 0.017	3.765GluGly: 3.765 ± 0.027	1.45GluHis: 1.45 ± 0.017	3.118GluIle: 3.118 ± 0.023	3.866GluLys: 3.866 ± 0.037	5.173GluLeu: 5.173 ± 0.034	1.506GluMet: 1.506 ± 0.016	2.425GluAsn: 2.425 ± 0.02	3.095GluPro: 3.095 ± 0.037	2.488GluGln: 2.488 ± 0.021	3.75GluArg: 3.75 ± 0.034	4.394GluSer: 4.394 ± 0.031	3.892GluThr: 3.892 ± 0.029	3.633GluVal: 3.633 ± 0.027	0.941GluTrp: 0.941 ± 0.013	1.735GluTyr: 1.735 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.976PheAla: 2.976 ± 0.024	0.586PheCys: 0.586 ± 0.009	2.344PheAsp: 2.344 ± 0.019	2.246PheGlu: 2.246 ± 0.022	1.649PhePhe: 1.649 ± 0.02	2.863PheGly: 2.863 ± 0.027	0.929PheHis: 0.929 ± 0.013	1.929PheIle: 1.929 ± 0.021	1.692PheLys: 1.692 ± 0.017	3.386PheLeu: 3.386 ± 0.027	0.847PheMet: 0.847 ± 0.012	1.548PheAsn: 1.548 ± 0.016	1.878PhePro: 1.878 ± 0.019	1.42PheGln: 1.42 ± 0.016	1.885PheArg: 1.885 ± 0.02	2.91PheSer: 2.91 ± 0.025	2.246PheThr: 2.246 ± 0.019	2.41PheVal: 2.41 ± 0.019	0.692PheTrp: 0.692 ± 0.011	1.138PheTyr: 1.138 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.05GlyAla: 5.05 ± 0.04	0.887GlyCys: 0.887 ± 0.013	3.752GlyAsp: 3.752 ± 0.032	3.562GlyGlu: 3.562 ± 0.024	2.819GlyPhe: 2.819 ± 0.025	5.402GlyGly: 5.402 ± 0.05	1.686GlyHis: 1.686 ± 0.017	3.601GlyIle: 3.601 ± 0.026	3.506GlyLys: 3.506 ± 0.032	5.986GlyLeu: 5.986 ± 0.039	1.584GlyMet: 1.584 ± 0.017	2.699GlyAsn: 2.699 ± 0.027	3.276GlyPro: 3.276 ± 0.031	2.598GlyGln: 2.598 ± 0.023	3.895GlyArg: 3.895 ± 0.03	5.603GlySer: 5.603 ± 0.045	4.006GlyThr: 4.006 ± 0.047	4.177GlyVal: 4.177 ± 0.03	1.2GlyTrp: 1.2 ± 0.015	2.174GlyTyr: 2.174 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.705HisAla: 1.705 ± 0.016	0.327HisCys: 0.327 ± 0.007	1.428HisAsp: 1.428 ± 0.018	1.405HisGlu: 1.405 ± 0.014	0.92HisPhe: 0.92 ± 0.011	1.699HisGly: 1.699 ± 0.018	0.836HisHis: 0.836 ± 0.018	1.237HisIle: 1.237 ± 0.014	0.993HisLys: 0.993 ± 0.014	2.175HisLeu: 2.175 ± 0.021	0.526HisMet: 0.526 ± 0.01	0.888HisAsn: 0.888 ± 0.012	1.521HisPro: 1.521 ± 0.019	1.014HisGln: 1.014 ± 0.014	1.459HisArg: 1.459 ± 0.018	1.712HisSer: 1.712 ± 0.016	1.198HisThr: 1.198 ± 0.014	1.411HisVal: 1.411 ± 0.015	0.367HisTrp: 0.367 ± 0.007	0.727HisTyr: 0.727 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.282IleAla: 4.282 ± 0.029	0.766IleCys: 0.766 ± 0.012	3.025IleAsp: 3.025 ± 0.023	3.075IleGlu: 3.075 ± 0.025	2.036IlePhe: 2.036 ± 0.021	3.246IleGly: 3.246 ± 0.027	1.198IleHis: 1.198 ± 0.014	2.704IleIle: 2.704 ± 0.028	2.425IleLys: 2.425 ± 0.022	4.536IleLeu: 4.536 ± 0.031	1.099IleMet: 1.099 ± 0.014	1.94IleAsn: 1.94 ± 0.019	3.054IlePro: 3.054 ± 0.025	1.963IleGln: 1.963 ± 0.02	2.79IleArg: 2.79 ± 0.024	3.88IleSer: 3.88 ± 0.023	3.037IleThr: 3.037 ± 0.038	3.282IleVal: 3.282 ± 0.026	0.823IleTrp: 0.823 ± 0.014	1.452IleTyr: 1.452 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.48LysAla: 4.48 ± 0.031	0.562LysCys: 0.562 ± 0.012	3.188LysAsp: 3.188 ± 0.023	3.584LysGlu: 3.584 ± 0.031	1.565LysPhe: 1.565 ± 0.017	3.164LysGly: 3.164 ± 0.025	1.208LysHis: 1.208 ± 0.016	2.391LysIle: 2.391 ± 0.022	3.611LysLys: 3.611 ± 0.039	4.194LysLeu: 4.194 ± 0.032	1.094LysMet: 1.094 ± 0.012	1.947LysAsn: 1.947 ± 0.021	2.969LysPro: 2.969 ± 0.031	1.978LysGln: 1.978 ± 0.02	3.355LysArg: 3.355 ± 0.029	3.647LysSer: 3.647 ± 0.03	3.146LysThr: 3.146 ± 0.026	2.974LysVal: 2.974 ± 0.024	0.743LysTrp: 0.743 ± 0.01	1.441LysTyr: 1.441 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.43LeuAla: 7.43 ± 0.038	1.22LeuCys: 1.22 ± 0.015	5.179LeuAsp: 5.179 ± 0.034	5.53LeuGlu: 5.53 ± 0.042	3.303LeuPhe: 3.303 ± 0.024	5.711LeuGly: 5.711 ± 0.035	2.1LeuHis: 2.1 ± 0.021	4.045LeuIle: 4.045 ± 0.028	4.302LeuLys: 4.302 ± 0.032	7.825LeuLeu: 7.825 ± 0.053	1.813LeuMet: 1.813 ± 0.017	3.252LeuAsn: 3.252 ± 0.021	5.239LeuPro: 5.239 ± 0.033	3.679LeuGln: 3.679 ± 0.029	5.324LeuArg: 5.324 ± 0.034	7.007LeuSer: 7.007 ± 0.042	4.752LeuThr: 4.752 ± 0.029	5.31LeuVal: 5.31 ± 0.034	1.252LeuTrp: 1.252 ± 0.015	2.349LeuTyr: 2.349 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.296MetAla: 2.296 ± 0.02	0.25MetCys: 0.25 ± 0.007	1.318MetAsp: 1.318 ± 0.015	1.323MetGlu: 1.323 ± 0.015	0.787MetPhe: 0.787 ± 0.012	1.529MetGly: 1.529 ± 0.015	0.491MetHis: 0.491 ± 0.008	1.054MetIle: 1.054 ± 0.015	1.117MetLys: 1.117 ± 0.015	1.818MetLeu: 1.818 ± 0.017	0.638MetMet: 0.638 ± 0.01	0.86MetAsn: 0.86 ± 0.013	1.343MetPro: 1.343 ± 0.016	0.836MetGln: 0.836 ± 0.012	1.239MetArg: 1.239 ± 0.014	2.003MetSer: 2.003 ± 0.018	1.383MetThr: 1.383 ± 0.016	1.346MetVal: 1.346 ± 0.016	0.278MetTrp: 0.278 ± 0.007	0.545MetTyr: 0.545 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.13AsnAla: 3.13 ± 0.022	0.48AsnCys: 0.48 ± 0.01	2.217AsnAsp: 2.217 ± 0.022	2.188AsnGlu: 2.188 ± 0.02	1.429AsnPhe: 1.429 ± 0.015	3.051AsnGly: 3.051 ± 0.028	0.893AsnHis: 0.893 ± 0.011	2.118AsnIle: 2.118 ± 0.02	1.84AsnLys: 1.84 ± 0.019	3.292AsnLeu: 3.292 ± 0.025	0.931AsnMet: 0.931 ± 0.012	1.687AsnAsn: 1.687 ± 0.024	2.446AsnPro: 2.446 ± 0.02	1.416AsnGln: 1.416 ± 0.018	1.981AsnArg: 1.981 ± 0.02	2.859AsnSer: 2.859 ± 0.022	2.307AsnThr: 2.307 ± 0.02	2.383AsnVal: 2.383 ± 0.023	0.624AsnTrp: 0.624 ± 0.01	1.101AsnTyr: 1.101 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.966ProAla: 4.966 ± 0.047	0.531ProCys: 0.531 ± 0.009	3.316ProAsp: 3.316 ± 0.026	4.11ProGlu: 4.11 ± 0.032	2.044ProPhe: 2.044 ± 0.017	3.939ProGly: 3.939 ± 0.064	1.24ProHis: 1.24 ± 0.017	2.578ProIle: 2.578 ± 0.021	2.899ProLys: 2.899 ± 0.028	4.455ProLeu: 4.455 ± 0.03	1.133ProMet: 1.133 ± 0.015	2.23ProAsn: 2.23 ± 0.019	4.704ProPro: 4.704 ± 0.066	2.487ProGln: 2.487 ± 0.028	3.21ProArg: 3.21 ± 0.03	5.658ProSer: 5.658 ± 0.045	3.943ProThr: 3.943 ± 0.035	3.589ProVal: 3.589 ± 0.031	0.775ProTrp: 0.775 ± 0.012	1.521ProTyr: 1.521 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.445GlnAla: 3.445 ± 0.027	0.462GlnCys: 0.462 ± 0.009	2.311GlnAsp: 2.311 ± 0.02	2.544GlnGlu: 2.544 ± 0.027	1.278GlnPhe: 1.278 ± 0.015	2.51GlnGly: 2.51 ± 0.024	1.048GlnHis: 1.048 ± 0.016	1.87GlnIle: 1.87 ± 0.016	2.01GlnLys: 2.01 ± 0.017	3.343GlnLeu: 3.343 ± 0.025	0.902GlnMet: 0.902 ± 0.013	1.607GlnAsn: 1.607 ± 0.017	2.569GlnPro: 2.569 ± 0.034	2.423GlnGln: 2.423 ± 0.042	2.483GlnArg: 2.483 ± 0.025	3.053GlnSer: 3.053 ± 0.027	2.348GlnThr: 2.348 ± 0.023	2.253GlnVal: 2.253 ± 0.019	0.601GlnTrp: 0.601 ± 0.008	1.167GlnTyr: 1.167 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.264ArgAla: 4.264 ± 0.031	0.706ArgCys: 0.706 ± 0.012	3.442ArgAsp: 3.442 ± 0.03	3.595ArgGlu: 3.595 ± 0.031	2.083ArgPhe: 2.083 ± 0.016	3.503ArgGly: 3.503 ± 0.028	1.501ArgHis: 1.501 ± 0.016	2.808ArgIle: 2.808 ± 0.024	3.319ArgLys: 3.319 ± 0.031	5.151ArgLeu: 5.151 ± 0.038	1.298ArgMet: 1.298 ± 0.015	2.259ArgAsn: 2.259 ± 0.02	3.368ArgPro: 3.368 ± 0.027	2.513ArgGln: 2.513 ± 0.024	4.662ArgArg: 4.662 ± 0.043	4.469ArgSer: 4.469 ± 0.036	3.116ArgThr: 3.116 ± 0.026	3.185ArgVal: 3.185 ± 0.021	0.918ArgTrp: 0.918 ± 0.014	1.67ArgTyr: 1.67 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.13SerAla: 6.13 ± 0.034	0.894SerCys: 0.894 ± 0.013	4.449SerAsp: 4.449 ± 0.034	4.32SerGlu: 4.32 ± 0.031	3.056SerPhe: 3.056 ± 0.022	5.361SerGly: 5.361 ± 0.039	1.893SerHis: 1.893 ± 0.019	4.115SerIle: 4.115 ± 0.026	3.874SerLys: 3.874 ± 0.028	6.884SerLeu: 6.884 ± 0.04	1.76SerMet: 1.76 ± 0.017	3.071SerAsn: 3.071 ± 0.026	5.157SerPro: 5.157 ± 0.042	3.301SerGln: 3.301 ± 0.026	4.703SerArg: 4.703 ± 0.038	8.036SerSer: 8.036 ± 0.059	5.504SerThr: 5.504 ± 0.048	4.506SerVal: 4.506 ± 0.03	1.191SerTrp: 1.191 ± 0.014	2.14SerTyr: 2.14 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.104ThrAla: 5.104 ± 0.034	0.788ThrCys: 0.788 ± 0.012	3.053ThrAsp: 3.053 ± 0.023	3.444ThrGlu: 3.444 ± 0.033	2.291ThrPhe: 2.291 ± 0.019	4.186ThrGly: 4.186 ± 0.037	1.247ThrHis: 1.247 ± 0.015	3.33ThrIle: 3.33 ± 0.047	2.94ThrLys: 2.94 ± 0.023	5.186ThrLeu: 5.186 ± 0.035	1.254ThrMet: 1.254 ± 0.014	2.244ThrAsn: 2.244 ± 0.02	4.246ThrPro: 4.246 ± 0.043	2.176ThrGln: 2.176 ± 0.02	3.115ThrArg: 3.115 ± 0.026	5.309ThrSer: 5.309 ± 0.04	4.614ThrThr: 4.614 ± 0.073	3.889ThrVal: 3.889 ± 0.062	0.917ThrTrp: 0.917 ± 0.013	1.675ThrTyr: 1.675 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.119ValAla: 5.119 ± 0.035	0.849ValCys: 0.849 ± 0.015	3.735ValAsp: 3.735 ± 0.028	3.975ValGlu: 3.975 ± 0.029	2.484ValPhe: 2.484 ± 0.024	3.89ValGly: 3.89 ± 0.031	1.36ValHis: 1.36 ± 0.016	3.058ValIle: 3.058 ± 0.031	3.087ValLys: 3.087 ± 0.024	5.394ValLeu: 5.394 ± 0.036	1.351ValMet: 1.351 ± 0.015	2.277ValAsn: 2.277 ± 0.02	3.56ValPro: 3.56 ± 0.032	2.382ValGln: 2.382 ± 0.021	3.232ValArg: 3.232 ± 0.024	4.555ValSer: 4.555 ± 0.031	3.743ValThr: 3.743 ± 0.054	4.237ValVal: 4.237 ± 0.036	0.888ValTrp: 0.888 ± 0.012	1.761ValTyr: 1.761 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.171TrpAla: 1.171 ± 0.016	0.21TrpCys: 0.21 ± 0.006	0.969TrpAsp: 0.969 ± 0.014	0.906TrpGlu: 0.906 ± 0.012	0.594TrpPhe: 0.594 ± 0.009	0.985TrpGly: 0.985 ± 0.014	0.379TrpHis: 0.379 ± 0.007	0.834TrpIle: 0.834 ± 0.012	0.884TrpLys: 0.884 ± 0.012	1.415TrpLeu: 1.415 ± 0.016	0.386TrpMet: 0.386 ± 0.008	0.684TrpAsn: 0.684 ± 0.011	0.649TrpPro: 0.649 ± 0.011	0.611TrpGln: 0.611 ± 0.009	0.916TrpArg: 0.916 ± 0.013	1.115TrpSer: 1.115 ± 0.012	0.986TrpThr: 0.986 ± 0.015	0.926TrpVal: 0.926 ± 0.014	0.29TrpTrp: 0.29 ± 0.008	0.474TrpTyr: 0.474 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.113TyrAla: 2.113 ± 0.021	0.441TyrCys: 0.441 ± 0.008	1.739TyrAsp: 1.739 ± 0.018	1.625TyrGlu: 1.625 ± 0.015	1.203TyrPhe: 1.203 ± 0.016	2.104TyrGly: 2.104 ± 0.024	0.779TyrHis: 0.779 ± 0.01	1.416TyrIle: 1.416 ± 0.015	1.245TyrLys: 1.245 ± 0.016	2.598TyrLeu: 2.598 ± 0.021	0.656TyrMet: 0.656 ± 0.01	1.211TyrAsn: 1.211 ± 0.017	1.487TyrPro: 1.487 ± 0.019	1.152TyrGln: 1.152 ± 0.013	1.634TyrArg: 1.634 ± 0.016	2.02TyrSer: 2.02 ± 0.018	1.666TyrThr: 1.666 ± 0.021	1.658TyrVal: 1.658 ± 0.021	0.491TyrTrp: 0.491 ± 0.009	0.946TyrTyr: 0.946 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.006XaaXaa: 0.006 ± 0.003

Statistics based on 13039 proteins (6531987 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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